4008-48-4 | 8-Hydroxy-5-nitroquinoline

Packsize	Purity	Availability	Price	Discounted Price
100mg	97%	in stock	$8.00	$5.00
1g	97%	in stock	$10.00	$7.00
5g	97%	in stock	$12.00	$8.00
25g	97%	in stock	$25.00	$17.00
500g	97%	in stock	$386.00	$270.00

Description

• Catalog Number: AF56320
• Chemical Name: 8-Hydroxy-5-nitroquinoline
• CAS Number: 4008-48-4
• Molecular Formula: C9H6N2O3
• Molecular Weight: 190.15554000000003
• MDL Number: MFCD00006791
• SMILES: O=N(=O)c1ccc(c2c1cccn2)O

Computed Properties

• Complexity: 229
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• XLogP3: 2.1

Literature

• Experimental and theoretical quantum chemical investigations of 8-hydroxy-5-nitroquinoline.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121001

• Synthesis and characterization of 8-hydroxyquinoline complexes of tin(IV) and their application in organic light emitting diode.

  Journal of fluorescence 20120901

• Substituted oxines inhibit endothelial cell proliferation and angiogenesis.

  Organic & biomolecular chemistry 20120421

• Cox-2 gene overexpression in ureteral stump urothelial carcinoma following nephrectomy for renal cell carcinoma: a case report.

  Journal of medical case reports 20120101

• Nitroxoline (8-hydroxy-5-nitroquinoline) is more a potent anti-cancer agent than clioquinol (5-chloro-7-iodo-8-quinoline).

  Cancer letters 20111215

• Novel mechanism of cathepsin B inhibition by antibiotic nitroxoline and related compounds.

  ChemMedChem 20110801

• Electrochemistry of the antibacterial and antifungal drug nitroxoline and its determination in bulk form, pharmaceutical formulation and human blood.

  Bioelectrochemistry (Amsterdam, Netherlands) 20110201

• Synergistic inhibition of endothelial cell proliferation, tube formation, and sprouting by cyclosporin A and itraconazole.

  PloS one 20110101

• Redox-based inactivation of cysteine cathepsins by compounds containing the 4-aminophenol moiety.

  PloS one 20110101

• Effect of nitroxoline on angiogenesis and growth of human bladder cancer.

  Journal of the National Cancer Institute 20101215

• Thermodynamic investigations of nitroxoline sublimation by simultaneous DSC-FTIR method and isothermal TG analysis.

  Journal of pharmaceutical sciences 20100101

• Evaluation of a Rapid Differentiation Test for Mycobacterium Tuberculosis from other Mycobacteria by Selective Inhibition with p-nitrobenzoic Acid using MGIT 960.

  Journal of laboratory physicians 20100101

• [Species composition and antibiotic resistance of lactobacillus in infants].

  Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20100101

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Powder diffraction study of the hydrogen bonds in nitroxoline and its hydrochloride.

  Acta crystallographica. Section C, Crystal structure communications 20020101

• [Is nitroxoline an allergen?].

  Therapie 20020101

• In vitro activity of the chelating agents nitroxoline and oxine against Mycobacterium bovis BCG.

  International journal of antimicrobial agents 20011201