4046-02-0 | Ferulic acid ethyl ester

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$7.00	$5.00
10g	98%	in stock	$9.00	$6.00
25g	98%	in stock	$20.00	$14.00
100g	95%	in stock	$70.00	$49.00

Description

• Catalog Number: AB67631
• Chemical Name: Ferulic acid ethyl ester
• CAS Number: 4046-02-0
• Molecular Formula: C12H14O4
• Molecular Weight: 222.2372
• MDL Number: MFCD00009190
• SMILES: CCOC(=O)C=Cc1ccc(c(c1)OC)O
• NSC Number: 14879

Computed Properties

• Complexity: 249
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 5
• XLogP3: 2.2

Literature

• Biological activity evaluation and structure-activity relationships analysis of ferulic acid and caffeic acid derivatives for anticancer.

  Bioorganic & medicinal chemistry letters 20121001

• Hydroxycinnamic acid ethyl esters as precursors to ethylphenols in wine.

  Journal of agricultural and food chemistry 20120307

• Taste-guided fractionation and instrumental analysis of hydrophobic compounds in sake.

  Bioscience, biotechnology, and biochemistry 20120101

• Synthesis of ethyl ferulate in organic medium using celite-immobilized lipase.

  Bioresource technology 20110201

• Identification of curcumin derivatives as human glyoxalase I inhibitors: A combination of biological evaluation, molecular docking, 3D-QSAR and molecular dynamics simulation studies.

  Bioorganic & medicinal chemistry 20110201

• Two new cytotoxic labdane diterpenes from the rhizomes of Hedychium coronarium.

  Bioorganic & medicinal chemistry letters 20101215

• Therapeutic potential of dietary polyphenols against brain ageing and neurodegenerative disorders.

  Advances in experimental medicine and biology 20100101

• 1,3-Diferuloyl-sn-glycerol from the biocatalytic transesterification of ethyl 4-hydroxy-3-methoxy cinnamic acid (ethyl ferulate) and soybean oil.

  Biotechnology letters 20090601

• Dual response surface-optimized process for feruloylated diacylglycerols by selective lipase-catalyzed transesterification in solvent free system.

  Bioresource technology 20090601

• New insights into the antioxidant activity of hydroxycinnamic acids: Synthesis and physicochemical characterization of novel halogenated derivatives.

  European journal of medicinal chemistry 20090501

• Ferulate-coniferyl alcohol cross-coupled products formed by radical coupling reactions.

  Planta 20090401

• Protective effect of ferulic acid ethyl ester against oxidative stress mediated by UVB irradiation in human epidermal melanocytes.

  Free radical research 20090401

• Peroxidase-catalyzed oligomerization of ferulic acid esters.

  Journal of agricultural and food chemistry 20081112

• Caffeic acid phenethyl ester and its related compounds limit the functional alterations of the isolated mouse brain and liver mitochondria submitted to in vitro anoxia-reoxygenation: relationship to their antioxidant activities.

  Biochimica et biophysica acta 20080401

• Redox regulation of cellular stress response by ferulic acid ethyl ester in human dermal fibroblasts: role of vitagenes.

  Clinics in dermatology 20080101

• A novel recombinant ethyl ferulate esterase from Burkholderia multivorans.

  Journal of applied microbiology 20071101

• Screening and analysis of an antineoplastic compound in Rhizoma Chuanxiong by means of in vitro metabolism and HPLC-MS.

  Analytical and bioanalytical chemistry 20060901

• In vivo protective effects of ferulic acid ethyl ester against amyloid-beta peptide 1-42-induced oxidative stress.

  Journal of neuroscience research 20060801

• Enzymatic synthesis of cinnamic acid derivatives.

  Biotechnology letters 20060401

• In vivo protection of synaptosomes by ferulic acid ethyl ester (FAEE) from oxidative stress mediated by 2,2-azobis(2-amidino-propane)dihydrochloride (AAPH) or Fe(2+)/H(2)O(2): insight into mechanisms of neuroprotection and relevance to oxidative stress-related neurodegenerative disorders.

  Neurochemistry international 20060301

• Characterization of enzymatically synthesized diferulate.

  Annals of the New York Academy of Sciences 20050601

• Ferulic acid ethyl ester protects neurons against amyloid beta- peptide(1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity.

  Journal of neurochemistry 20050201

• Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress.

  Antioxidants & redox signaling 20041001

• Protective effects of the lipophilic redox conjugate tocopheryl succinyl-ethyl ferulate on HIV replication.

  FEBS letters 19971124