4071-88-9 | Ethyl (trimethylsilyl)acetate

Packsize	Purity	Availability	Price	Discounted Price
10g	98%	in stock	$11.00	$8.00
15g	98%	in stock	$13.00	$10.00
25g	98%	in stock	$17.00	$12.00

Description

• Catalog Number: AF57401
• Chemical Name: Ethyl (trimethylsilyl)acetate
• CAS Number: 4071-88-9
• Molecular Formula: C7H16O2Si
• Molecular Weight: 160.2862
• MDL Number: MFCD00009172
• SMILES: CCOC(=O)C[Si](C)(C)C

Computed Properties

• Complexity: 115
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4

Upstream Synthesis Route

Ethyl 2-(trimethylsilyl)acetate is a versatile compound widely used in chemical synthesis for its unique properties and reactivity. As a trimethylsilyl derivative of acetate, this compound serves as a valuable building block in organic reactions, providing a means to introduce acetyl functionality while also offering protection for sensitive functional groups.In chemical synthesis, Ethyl 2-(trimethylsilyl)acetate can be employed as a precursor for the introduction of an acetyl group into organic molecules. This acetylation process is commonly utilized in the modification of natural products, pharmaceuticals, and complex organic compounds to alter their properties or enhance their activities. Furthermore, the trimethylsilyl group serves as a temporary protecting group for reactive functional groups such as alcohols and amines, allowing for selective manipulation of specific sites within a molecule without affecting other parts of the structure. By strategically incorporating Ethyl 2-(trimethylsilyl)acetate into synthetic schemes, chemists can streamline multi-step reactions, control regioselectivity, and improve overall yields, making it an indispensable tool in modern organic synthesis strategies.

Literature

• 1-Phenyl-5-{[2-(trimethyl-sil-yl)eth-yl]sulfon-yl}-1H-tetra-zole.

  Acta crystallographica. Section E, Structure reports online 20110901