40957-83-3 | Glycitein

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$14.00	$10.00
5mg	98%	in stock	$35.00	$25.00
500mg	98% by HPLC	in stock	$2,989.00	$2,092.00
1000mg	98% by HPLC	in stock	$4,749.00	$3,324.00

Description

• Catalog Number: AI50006
• Chemical Name: Glycitein
• CAS Number: 40957-83-3
• Molecular Formula: C16H12O5
• Molecular Weight: 284.2635
• MDL Number: MFCD00016679
• SMILES: COc1cc2c(cc1O)occ(c2=O)c1ccc(cc1)O

Computed Properties

• Complexity: 424
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 21
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 2.4

Literature

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• Genistein and other soya isoflavones are potent ligands for transthyretin in serum and cerebrospinal fluid.

  The British journal of nutrition 20060601

• Development and validation of a RP-HPLC method for quantification of isoflavone aglycones in hydrolyzed soy dry extracts.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060519

• Antioxidant activity of isoflavones and their major metabolites using different in vitro assays.

  Journal of agricultural and food chemistry 20060419

• Prostatic fluid concentrations of isoflavonoids in soy consumers are sufficient to inhibit growth of benign and malignant prostatic epithelial cells in vitro.

  The Prostate 20060401

• Thermal degradation kinetics of isoflavone aglycones from soy and red clover.

  Molecular nutrition & food research 20060401

• Isoflavones inhibit nicotine C-oxidation catalyzed by human CYP2A6.

  Journal of clinical pharmacology 20060301

• Determination of isoflavones in dietary supplements containing soy, Red Clover and kudzu: extraction followed by basic or acid hydrolysis.

  Journal of chromatography. A 20060224

• Distribution profiles of isoflavone isomers in black bean kojis prepared with various filamentous fungi.

  Journal of agricultural and food chemistry 20060222

• Soybean isoflavones alter parvalbumin in hippocampus of mid-aged normal female, ovariectomized female, and normal male rats.

  Acta pharmacologica Sinica 20060101

• Oncogenicity evaluations of chemopreventive soy components in p53((+/-)) (p53 knockout) mice.

  International journal of toxicology 20060101

• Phytoestrogen content of foods consumed in Canada, including isoflavones, lignans, and coumestan.

  Nutrition and cancer 20060101

• Analysis of isoflavones in foods and dietary supplements.

  Journal of AOAC International 20060101

• An accurate and reproducible method for the quantitative analysis of isoflavones and their metabolites in rat plasma using liquid chromatography/mass spectrometry combined with photodiode array detection.

  Journal of AOAC International 20060101

• Identification of estrogen-regulated genes by microarray analysis of the uterus of immature rats exposed to endocrine disrupting chemicals.

  Reproductive biology and endocrinology : RB&E 20060101

• Transcriptome changes in the phenylpropanoid pathway of Glycine max in response to Pseudomonas syringae infection.

  BMC plant biology 20060101

• Estimated intakes of isoflavones and coumestrol in Korean population.

  International journal of food sciences and nutrition 20060101

• Phytoestrogen exposure, polymorphisms in COMT, CYP19, ESR1, and SHBG genes, and their associations with prostate cancer risk.

  Nutrition and cancer 20060101

• Isoflavones modulate the glucuronidation of estradiol in human liver microsomes.

  Carcinogenesis 20051201

• [Preparation of soybean isoflavone aglycones by reversed-phase high performance liquid chromatography from Semen Sojae Praeparatum].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20051201

• Metabolism of glycitein (7,4'-dihydroxy-6-methoxy-isoflavone) by human gut microflora.

  Journal of agricultural and food chemistry 20051102

• Identifying 6,7,4'-trihydroxyisoflavone as a potent tyrosinase inhibitor.

  Bioscience, biotechnology, and biochemistry 20051001

• Isoflavone contents in germinated soybean seeds.

  Plant foods for human nutrition (Dordrecht, Netherlands) 20050901

• Determination of isoflavones in soy bits by fast column high-performance liquid chromatography coupled with UV-visible diode-array detection.

  Journal of chromatography. A 20050819

• Supercritical fluid extraction of isoflavones from biological samples with ultra-fast high-performance liquid chromatography/mass spectrometry.

  Journal of separation science 20050801

• Quantitative determination and structural characterization of isoflavones in nutrition supplements by liquid chromatography-mass spectrometry.

  Journal of chromatography. A 20050729

• Evaluation of isoflavone aglycon and glycoside distribution in soy plants and soybeans by fast column high-performance liquid chromatography coupled with a diode-array detector.

  Journal of agricultural and food chemistry 20050727

• The transgenic Arabidopsis plant system, pER8-GFP, as a powerful tool in searching for natural product estrogen-agonists/antagonists.

  Journal of natural products 20050701

• Optimization of conditions for the enzymatic hydrolysis of phytoestrogen conjugates in urine and plasma.

  Analytical biochemistry 20050615

• Experimental determination of octanol-water partition coefficients of quercetin and related flavonoids.

  Journal of agricultural and food chemistry 20050601

• Bioavailability of isoflavone phytoestrogens in postmenopausal women consuming soya milk fermented with probiotic bifidobacteria.

  The British journal of nutrition 20050601

• Daidzein-rich isoflavone-aglycones for menopausal symptoms.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20050401

• Expression profiling of the estrogen responsive genes in response to phytoestrogens using a customized DNA microarray.

  FEBS letters 20050314

• Absorption and metabolism of genistein and its five isoflavone analogs in the human intestinal Caco-2 model.

  Cancer chemotherapy and pharmacology 20050201

• Phytoestrogen exposure correlation with plasma estradiol in postmenopausal women in European Prospective Investigation of Cancer and Nutrition-Norfolk may involve diet-gene interactions.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050101

• A randomized, placebo-controlled trial on the effects of soy protein containing isoflavones on quality of life in postmenopausal women.

  Menopause (New York, N.Y.) 20050101

• Pharmacokinetics of isoflavones, daidzein and genistein, after ingestion of soy beverage compared with soy extract capsules in postmenopausal Thai women.

  BMC clinical pharmacology 20050101

• Soy isoflavone glycitein protects against beta amyloid-induced toxicity and oxidative stress in transgenic Caenorhabditis elegans.

  BMC neuroscience 20050101

• In vitro effects of soy phytoestrogens on rat L6 skeletal muscle cells.

  Journal of medicinal food 20050101

• Phytoestrogens: end of a tale?

  Annals of medicine 20050101

• Quality, labeling accuracy, and cost comparison of purified soy isoflavonoid products.

  Journal of alternative and complementary medicine (New York, N.Y.) 20041201

• Soy isoflavones suppress invasiveness of breast cancer cells by the inhibition of NF-kappaB/AP-1-dependent and -independent pathways.

  International journal of oncology 20041101

• Cumulative dietary energy intake determines the onset of puberty in female rats.

  Environmental health perspectives 20041101

• Impact of the phytoestrogen content of laboratory animal feed on the gene expression profile of the reproductive system in the immature female rat.

  Environmental health perspectives 20041101

• Potential beneficial metabolic interactions between tamoxifen and isoflavones via cytochrome P450-mediated pathways in female rat liver microsomes.

  Pharmaceutical research 20041101

• Decreased bone resorption with soy isoflavone supplementation in postmenopausal women.

  Journal of women's health (2002) 20041101

• Biotransformation of soy isoflavone-glycosides in laying hens: intestinal absorption and preferential accumulation into egg yolk of equol, a more estrogenic metabolite of daidzein.

  Biochimica et biophysica acta 20040924

• Effects of a diet rich in phytoestrogens on prostate-specific antigen and sex hormones in men diagnosed with prostate cancer.

  Urology 20040901

• Synthesis of phytoestrogenic isoflavonoid disulfates.

  Steroids 20040901

• Plant lignans in soy-based health supplements.

  Journal of agricultural and food chemistry 20040630

• Reproductive toxicity assessment of chronic dietary exposure to soy isoflavones in male rats.

  Reproductive toxicology (Elmsford, N.Y.) 20040601

• Isolation of 8-hydroxyglycitein and 6-hydroxydaidzein from soybean miso.

  Bioscience, biotechnology, and biochemistry 20040601

• LC/UV/ESI-MS analysis of isoflavones in Edamame and Tofu soybeans.

  Journal of agricultural and food chemistry 20040519

• Differential effects of isoflavones and lignans on invasiveness of MDA-MB-231 breast cancer cells in vitro.

  Cancer letters 20040510

• Identification and concentration of soy phytoestrogens in commercial dog foods.

  American journal of veterinary research 20040501

• Phytoestrogen concentrations in serum and spot urine as biomarkers for dietary phytoestrogen intake and their relation to breast cancer risk in European prospective investigation of cancer and nutrition-norfolk.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040501

• Evaluation of the preventive effect of isoflavone extract on bone loss in ovariectomized rats.

  Bioscience, biotechnology, and biochemistry 20040501

• Isoflavones found in Korean soybean paste as 3-hydroxy-3-methylglutaryl Coenzyme A reductase inhibitors.

  Bioscience, biotechnology, and biochemistry 20040501

• Influence of soya-based infant formula consumption on isoflavone and gut microflora metabolite concentrations in urine and on faecal microflora composition and metabolic activity in infants and children.

  The British journal of nutrition 20040401

• Dietary exposure estimates of isoflavones from the 1998 UK Total Diet Study.

  Food additives and contaminants 20040401

• Recombinant human estrogen, androgen and progesterone receptors for detection of potential endocrine disruptors.

  Analytical and bioanalytical chemistry 20040201

• Interactions of phytoestrogens with estrogen receptors alpha and beta (III). Estrogenic activities of soy isoflavone aglycones and their metabolites isolated from human urine.

  Biological & pharmaceutical bulletin 20040201

• Cytotoxic effects of some animal and vegetable extracts and some chemicals on liver and colon carcinoma and myosarcoma.

  Saudi medical journal 20040201

• Isoflavones inhibit 3-hydroxy-3-methylglutaryl coenzyme A reductase in vitro.

  Bioscience, biotechnology, and biochemistry 20040201

• Simultaneous determination of isoflavones and bisphenol A in rat serum by high-performance liquid chromatography coupled with coulometric array detection.

  Bioscience, biotechnology, and biochemistry 20040101

• Soybean: feed quality and safety. Part 1: biologically active components. A review.

  Acta veterinaria Hungarica 20040101

• Reports: plasma and dietary phytoestrogens and risk of premalignant lesions of the cervix.

  Nutrition and cancer 20040101

• Soy and isoflavone intake are associated with reduced risk of ovarian cancer in southeast china.

  Nutrition and cancer 20040101

• Isoflavonoids in the Rutaceae family: 1. Fortunella obovata, Murraya paniculata and four Citrus species.

  Phytochemical analysis : PCA 20040101

• Analysis of isoflavone contents in vegetable soybeans.

  Plant foods for human nutrition (Dordrecht, Netherlands) 20040101

• Metabolism of the soy isoflavones daidzein, genistein and glycitein in human subjects. Identification of new metabolites having an intact isoflavonoid skeleton.

  The Journal of steroid biochemistry and molecular biology 20031201

• The influence of dietary isoflavone on the uterotrophic response in juvenile rats.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20031101

• Determination of isoflavones in red clover and related species by high-performance liquid chromatography combined with ultraviolet and mass spectrometric detection.

  Journal of chromatography. A 20031024

• Soy protein with or without isoflavones, soy germ and soy germ extract, and daidzein lessen plasma cholesterol levels in golden Syrian hamsters.

  Experimental biology and medicine (Maywood, N.J.) 20031001

• Serum isoflavones and soya food intake in Japanese, Thai and American end-stage renal disease patients on chronic haemodialysis.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030901

• Stability and bioaccessibility of isoflavones from soy bread during in vitro digestion.

  Journal of agricultural and food chemistry 20030730

• Effect of soy-derived isoflavones on hot flushes, endometrial thickness, and the pulsatility index of the uterine and cerebral arteries.

  Fertility and sterility 20030501

• Quantification of isoflavones and lignans in urine using gas chromatography/mass spectrometry.

  Analytical biochemistry 20030401

• Lactofen induces isoflavone accumulation and glyceollin elicitation competency in soybean.

  Phytochemistry 20030301

• Comparison of hormonal activity (estrogen, androgen and progestin) of standardized plant extracts for large scale use in hormone replacement therapy.

  The Journal of steroid biochemistry and molecular biology 20030201

• Isoflavone, glyphosate, and aminomethylphosphonic acid levels in seeds of glyphosate-treated, glyphosate-resistant soybean.

  Journal of agricultural and food chemistry 20030101

• A simple synthesis of 7,4'-dihydroxy-6-methoxyisoflavone, glycitein, the third soybean isoflavone.

  Journal of natural products 20030101

• Determination of isoflavones in ready-to-feed soy-based infant formula.

  Journal of AOAC International 20030101

• Quantification of isoflavones and lignans in serum using isotope dilution liquid chromatography/tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20030101

• Effects of isoflavones (soy phyto-estrogens) on serum lipids: a meta-analysis of randomized controlled trials.

  Nutrition journal 20030101

• Stabilities of daidzin, glycitin, genistin, and generation of derivatives during heating.

  Journal of agricultural and food chemistry 20021204

• Liquid chromatographic-photodiode array mass spectrometric analysis of dietary phytoestrogens from human urine and blood.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020925

• Oxidative metabolism and genotoxic potential of major isoflavone phytoestrogens.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020925

• Potassium fertilization effects on isoflavone concentrations in soybean [Glycine max (L.) Merr.].

  Journal of agricultural and food chemistry 20020605

• Potent antimutagenic and their anti-lipid peroxidative effect of kaikasaponin III and tectorigenin from the flower of Pueraria thunbergiana.

  Archives of pharmacal research 20020601

• Characterization of isoflavones and their conjugates in female rat urine using LC/MS/MS.

  Journal of agricultural and food chemistry 20020424

• Isoflavone aglycon and glucoconjugate content of high- and low-soy U.K. foods used in nutritional studies.

  Journal of agricultural and food chemistry 20020313

• Effects of naturally occurring isoflavones on prostaglandin E2 production.

  Planta medica 20020201

• Soy milk with a high glycitein content does not reduce low-density lipoprotein cholesterolemia in type II hypercholesterolemic patients.

  Annals of nutrition & metabolism 20020101

• A comparative study of growth-inhibitory effects of isoflavones and their metabolites on human breast and prostate cancer cell lines.

  Nutrition and cancer 20020101

• Different mechanisms of soy isoflavones in cell cycle regulation and inhibition of invasion.

  Anticancer research 20020101

• Effect of polyphenols on calcium content and alkaline phosphatase activity in rat femoral tissues in vitro.

  Biological & pharmaceutical bulletin 20011201

• Tectorigenin, an isoflavone of Pueraria thunbergiana Benth., induces differentiation and apoptosis in human promyelocytic leukemia HL-60 cells.

  Biological & pharmaceutical bulletin 20011001

• Separation and purification of isoflavones from a crude soybean extract by high-speed counter-current chromatography.

  Journal of chromatography. A 20010914

• Quantitative analysis of the principle soy isoflavones genistein, daidzein and glycitein, and their primary conjugated metabolites in human plasma and urine using reversed-phase high-performance liquid chromatography with ultraviolet detection.

  Journal of chromatography. B, Biomedical sciences and applications 20010905

• Effects of phytoestrogens on acetylcholine- and isoprenaline-induced vasodilation in rat aorta.

  Japanese journal of pharmacology 20010901

• Optimization of a yeast estrogen screen and its applicability to study the release of estrogenic isoflavones from a soygerm powder.

  Environmental health perspectives 20010701

• [Studies on chemical constituents of Maackia amurensis Rupr. et. Maxim].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20010601

• Glycitein effect on suppressing the proliferation and stimulating the differentiation of osteoblastic MC3T3-E1 cells.

  Bioscience, biotechnology, and biochemistry 20010501

• Suppression effect of soy isoflavones on nitric oxide production in RAW 264.7 macrophages.

  Journal of agricultural and food chemistry 20010401

• [Daily intake of isoflavones based on the market basket method].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20010401

• Determination of isoflavones in soy and selected foods containing soy by extraction, saponification, and liquid chromatography: collaborative study.

  Journal of AOAC International 20010101

• Characterisation of soy isoflavones and screening for novel malonyl glycosides using high-performance liquid chromatography-electrospray ionisation-mass spectrometry.

  Phytochemical analysis : PCA 20010101