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Vinpocetine reduces lipopolysaccharide-induced inflammatory pain and neutrophil recruitment in mice by targeting oxidative stress, cytokines and NF-κB.
Chemico-biological interactions 20150725
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Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Bioorganic & medicinal chemistry 20121115
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Vinpocetine suppresses pathological vascular remodeling by inhibiting vascular smooth muscle cell proliferation and migration.
The Journal of pharmacology and experimental therapeutics 20121101
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Vinpocetine inhibits breast cancer cells growth in vitro and in vivo.
Apoptosis : an international journal on programmed cell death 20121001
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Various phosphodiesterase activities in different regions of the heart alter the cardiac effects of nitric oxide.
Journal of cardiovascular pharmacology 20120901
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Early alcohol exposure disrupts visual cortex plasticity in mice.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20120801
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Nano-advantage in enhanced drug delivery with biodegradable nanoparticles: contribution of reduced clearance.
Drug metabolism and disposition: the biological fate of chemicals 20120701
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[Comment on the paper by A. Valikovics et al. 'The effect of vinpocetin on cognitive function' published in the issue 3-4 of this year].
Ideggyogyaszati szemle 20120530
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Chemical evolution of autotaxin inhibitors.
Chemical reviews 20120509
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The facilitating effect of prucalopride on cholinergic neurotransmission in pig gastric circular muscle is regulated by phosphodiesterase 4.
Neuropharmacology 20120401
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[The observation on curative effect of 90 cases of sudden hearing loss].
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20120401
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Chiral separation of vinpocetine using cyclodextrin-modified micellar electrokinetic chromatography.
Chirality 20120301
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Visualising neuroinflammation in post-stroke patients: a comparative PET study with the TSPO molecular imaging biomarkers [11C]PK11195 and [11C]vinpocetine.
Current radiopharmaceuticals 20120101
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Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery.
Journal of drug delivery 20120101
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Clinical utility of adjunctive retigabine in partial onset seizures in adults.
Therapeutics and clinical risk management 20120101
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Psychiatric symptoms of patients with primary mitochondrial DNA disorders.
Behavioral and brain functions : BBF 20120101
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Expression of calmodulin and myosin light chain kinase during larval settlement of the Barnacle Balanus amphitrite.
PloS one 20120101
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Role Ca(2+) in mechanisms of the red blood cells microrheological changes.
Advances in experimental medicine and biology 20120101
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Hesperetin, a Selective Phosphodiesterase 4 Inhibitor, Effectively Suppresses Ovalbumin-Induced Airway Hyperresponsiveness without Influencing Xylazine/Ketamine-Induced Anesthesia.
Evidence-based complementary and alternative medicine : eCAM 20120101
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Vinpocetine inhibits oligodendroglial precursor cell differentiation.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
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Acute administration of vinpocetine, a phosphodiesterase type 1 inhibitor, ameliorates hyperactivity in a mice model of fetal alcohol spectrum disorder.
Drug and alcohol dependence 20111201
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cGMP Signaling, Phosphodiesterases and Major Depressive Disorder.
Current neuropharmacology 20111201
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Effect of pentoxifylline and vinpocetine on the healing of ischemic colon anastomosis: an experimental study.
Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES 20111101
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Vinpocetine inhibits glutamate release induced by the convulsive agent 4-aminopyridine more potently than several antiepileptic drugs.
Epilepsy research 20111001
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Influence of admixed citric acid and physiological variables on the vinpocetine release from sodium alginate compressed matrix tablets.
Drug development and industrial pharmacy 20110801
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Enhanced oral bioavailability of vinpocetine through mechanochemical salt formation: physico-chemical characterization and in vivo studies.
Pharmaceutical research 20110801
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Age and disease related changes in the translocator protein (TSPO) system in the human brain: positron emission tomography measurements with [11C]vinpocetine.
NeuroImage 20110601
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Oxidative stress in a model of toxic demyelination in rat brain: the effect of piracetam and vinpocetine.
Neurochemical research 20110601
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Regulatory mechanism of duodenal bicarbonate secretion: Roles of endogenous prostaglandins and nitric oxide.
Pharmacology & therapeutics 20110401
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Preventive effect of piracetam and vinpocetine on hypoxia-reoxygenation induced injury in primary hippocampal culture.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110401
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[Interdisciplinary approach to vestibular system impairment].
Ideggyogyaszati szemle 20110330
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Multidisciplinary approach on characterizing a mechanochemically activated composite of vinpocetine and crospovidone.
Journal of pharmaceutical sciences 20110301
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Conserved expression and functions of PDE4 in rodent and human heart.
Basic research in cardiology 20110301
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Decreased cGMP level contributes to increased contraction in arteries from hypertensive rats: role of phosphodiesterase 1.
Hypertension (Dallas, Tex. : 1979) 20110301
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S-Petasin, the Main Sesquiterpene of Petasites formosanus, Inhibits Phosphodiesterase Activity and Suppresses Ovalbumin-Induced Airway Hyperresponsiveness.
Evidence-based complementary and alternative medicine : eCAM 20110101
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Novel sugar esters proniosomes for transdermal delivery of vinpocetine: preclinical and clinical studies.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110101
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Therapeutic utility of phosphodiesterase type I inhibitors in neurological conditions.
Frontiers in neuroscience 20110101
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Hyperbaric oxygen therapy in idiopathic sudden sensorineural hearing loss (ISSNHL) in association with combined treatment.
Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 20110101
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Identification of cytosolic phosphodiesterases in the erythrocyte: a possible role for PDE5.
Medical science monitor : international medical journal of experimental and clinical research 20110101
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[The use of vinpotropile in brain ischemia].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101
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Preparation and in vitro/in vivo evaluation of vinpocetine elementary osmotic pump system.
Advances in pharmacological sciences 20110101
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Reversing brain damage in former NFL players: implications for traumatic brain injury and substance abuse rehabilitation.
Journal of psychoactive drugs 20110101
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[Endothelium-protective effects of vinpocetine, pentoxifylline and enalapril in patients with chronic brain ischemia].
Eksperimental'naia i klinicheskaia farmakologiia 20110101
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Role of vinpocetine in cerebrovascular diseases.
Pharmacological reports : PR 20110101
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Red blood cell aggregation changes are depended on its initial value: Effect of long-term drug treatment and short-term cell incubation with drug.
Clinical hemorheology and microcirculation 20110101
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Effect of five common anticonvulsant drugs on naloxone-precipitated morphine withdrawal in mice.
Research in pharmaceutical sciences 20110101
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In situ formation of nanocrystals from a self-microemulsifying drug delivery system to enhance oral bioavailability of fenofibrate.
International journal of nanomedicine 20110101
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Pentoxifylline sensitizes human cervical tumor cells to cisplatin-induced apoptosis by suppressing NF-kappa B and decreased cell senescence.
BMC cancer 20110101
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Hesperetin-7,3'-O-dimethylether selectively inhibits phosphodiesterase 4 and effectively suppresses ovalbumin-induced airway hyperresponsiveness with a high therapeutic ratio.
Journal of biomedical science 20110101
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Omeprazole does not change the oral bioavailability or pharmacokinetics of vinpocetine in rats.
Pharmacological reports : PR 20110101
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Macro- and microrheological parameters of blood in patients with cerebral and peripheral atherosclerosis: the molecular change mechanisms after pentoxifylline treatment.
Clinical hemorheology and microcirculation 20110101
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Fabrication, appraisal, and transdermal permeation of sildenafil citrate-loaded nanostructured lipid carriers versus solid lipid nanoparticles.
International journal of nanomedicine 20110101
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[Potentials of the neuroprotective treatment of polymodal action in acute and early rehabilitation period of stroke].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101
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Separation of vinca alkaloid enantiomers by capillary electrophoresis applying cyclodextrin derivatives and characterization of cyclodextrin complexes by nuclear magnetic resonance spectroscopy.
Journal of pharmaceutical and biomedical analysis 20101215
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Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Bioorganic & medicinal chemistry letters 20101101
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Preparation and characterization of vinpocetine loaded nanostructured lipid carriers (NLC) for improved oral bioavailability.
International journal of pharmaceutics 20100715
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Determination of vinpocetine and its primary metabolite, apovincaminic acid, in rat plasma by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100715
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Antinociceptive effect of vinpocetine--a comprehensive survey.
Ideggyogyaszati szemle 20100530
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Phosphodiesterase type 1 inhibition improves learning in rats exposed to alcohol during the third trimester equivalent of human gestation.
Neuroscience letters 20100412
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Recent advances in adjunctive therapy for epilepsy: focus on sodium channel blockers as third-generation antiepileptic drugs.
Drugs of today (Barcelona, Spain : 1998) 20100401
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Prostaglandin EP receptor subtypes involved in regulating HCO(3)(-) secretion from gastroduodenal mucosa.
Current pharmaceutical design 20100101
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Effects of rolipram on U46619-induced contraction and cyclic nucleotide content in the porcine coronary artery.
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20100101
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[Possibilities of preventive treatment of Alzheimer's disease: results of the 3-year open prospective comparative study on efficacy and safety of the course therapy with cerebrolysin and cavinton in elderly patients with the syndrome of mild cognitive impairment].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
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Sensitization of cervix cancer cells to Adriamycin by Pentoxifylline induces an increase in apoptosis and decrease senescence.
Molecular cancer 20100101
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[Approaches to the therapy of neurological presentations in diabetes mellitus].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
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[Electrophoresis of vasoactive drugs in the treatment and rehabilitation of patients with cerebral ischemic diseases].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
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Crosstalk between adenylyl cyclase signaling pathway and Ca2+ regulatory mechanism under red blood cell microrheological changes.
Clinical hemorheology and microcirculation 20100101
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[Chronic disorders of cerebral blood circulation: possibilities of the use of cavinton].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
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Solid State Characterization of Domperidone: Hydroxypropyl-β-Cyclodextrin Inclusion Complex.
Indian journal of pharmaceutical sciences 20100101
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Recent advances in management of bladder overactivity.
F1000 medicine reports 20100101
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Preparation and in vitro/in vivo characterization of porous sublingual tablets containing ternary kneaded solid system of vinpocetine with î-cyclodextrin and hydroxy Acid.
Scientia pharmaceutica 20100101
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[Efficacy of vinpotropile in the therapy of initial signs of cerebrovascular pathology].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
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[Vinpotropil in the treatment of dyscirculatory encephalopathy with cognitive impairment without dementia].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
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[Efficacy of cavinton in the treatment of patients with chronic blood flow insufficiency. Russian multicenter clinical-epidemiological program 'CALIPSO'].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
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[Polymorphic effects of cavinton: experimental and clinical evidence].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
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[The use of cavinton and cerebrolusin in the preventive therapy of Alzheimer's disease].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
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Optimized preparation of vinpocetine proliposomes by a novel method and in vivo evaluation of its pharmacokinetics in New Zealand rabbits.
Journal of controlled release : official journal of the Controlled Release Society 20091116
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A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel.
Analytical biochemistry 20091101
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Calcium-dependent phosphodiesterase 1C inhibits renin release from isolated juxtaglomerular cells.
American journal of physiology. Regulatory, integrative and comparative physiology 20091101
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Effects of various selective phosphodiesterase inhibitors on relaxation and cyclic nucleotide contents in porcine iris sphincter.
The Journal of veterinary medical science 20091101
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The flavonoid dioclein is a selective inhibitor of cyclic nucleotide phosphodiesterase type 1 (PDE1) and a cGMP-dependent protein kinase (PKG) vasorelaxant in human vascular tissue.
European journal of pharmacology 20091012
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Amelioration of intracerebroventricular streptozotocin induced cognitive dysfunction and oxidative stress by vinpocetine -- a PDE1 inhibitor.
European journal of pharmacology 20091012
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Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Nature chemical biology 20091001
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[Significance of phosphodiesterase isoenzymes in the control of human detrusor smooth muscle function. An immunohistochemical and functional study].
Der Urologe. Ausg. A 20090701
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Effects of phosphodiesterase inhibitors on contraction induced by endothelin-1 of isolated human prostatic tissue.
Urology 20090601
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Comparison of self-microemulsifying drug delivery system versus solid dispersion technology used in the improvement of dissolution rate and bioavailability of vinpocetine.
Yao xue xue bao = Acta pharmaceutica Sinica 20090601
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Preparation and evaluation of self-microemulsifying drug delivery system containing vinpocetine.
Drug development and industrial pharmacy 20090501
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Characterization of phosphodiesterase 1 in human malignant melanoma cell lines.
Anticancer research 20090401
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Characterization of phenytoin, carbamazepine, vinpocetine and clorgyline simultaneous effects on sodium channels and catecholamine metabolism in rat striatal nerve endings.
Neurochemical research 20090301
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Effect of parenteral or oral vinpocetine on the hemorheological parameters of patients with chronic cerebrovascular diseases.
Phytomedicine : international journal of phytotherapy and phytopharmacology 20090301
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Effects of phosphodiesterase inhibitors on the contractile responses of isolated human seminal vesicle tissue to adrenergic stimulation.
The journal of sexual medicine 20090201
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Selective phosphodiesterase inhibitors: a promising target for cognition enhancement.
Psychopharmacology 20090101
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A novel PDE2A reporter cell line: characterization of the cellular activity of PDE inhibitors.
Molecular pharmaceutics 20090101
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Examination of a pre-exercise, high energy supplement on exercise performance.
Journal of the International Society of Sports Nutrition 20090101
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[Efficacy of dynamic magnetic therapy in the complex treatment of cognitive disturbances in patients with chronic cerebrovascular insufficiency].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101
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Neuroprotective effects of vinpocetine and its major metabolite cis-apovincaminic acid on NMDA-induced neurotoxicity in a rat entorhinal cortex lesion model.
CNS neuroscience & therapeutics 20090101
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Prediction and validation of a mechanism to control the threshold for inhibitory synaptic plasticity.
Molecular systems biology 20090101
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Phosphodiesterase inhibition increases CREB phosphorylation and restores orientation selectivity in a model of fetal alcohol spectrum disorders.
PloS one 20090101
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[Effect of cavinton forte on the cerebral hemodynamic and autoregulation mechanisms of cerebral blood flow in patients with chronic cerebral ischemia].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101
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[Cavinton in the complex treatment of patients with chronic cerebrovascular insufficiency].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101
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[A multicenter program on assessment of efficacy and safety of a new therapeutic scheme for patients with chronic cerebrovascular insufficiency].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101
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[Selective trabeculoplasty in combination with vasoactive agents in the complex treatment of primary open-angle glaucoma].
Vestnik oftalmologii 20090101
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[Membrane and functional effects of vinpocetine and tocopherol in rats with experimental cerebral ischemia].
Biomeditsinskaia khimiia 20090101
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[Cavinton in the treatment of cochleovestibular disorders of vascular genesis].
Vestnik otorinolaringologii 20090101
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[The new scheme of cavinton application to the treatment of chronic neurosensory loss of hearing].
Vestnik otorinolaringologii 20090101
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[The use of cavinton in the therapy of cognitive disorders in patients with discirculatory encephalopathy].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101
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[Positron-emission tomography in the diagnosis of middle cerebral artery lesions].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101
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Effects of Vinpocetine on mitochondrial function and neuroprotection in primary cortical neurons.
Neurochemistry international 20081201
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Development and validation of an adsorptive stripping voltammetric method for the quantification of vincamine in its formulations and human serum using a Nujol-based carbon paste electrode.
Chemical & pharmaceutical bulletin 20081201
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ABCD of the phosphodiesterase family: interaction and differential activity in COPD.
International journal of chronic obstructive pulmonary disease 20081201
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Comparison of acute, chronic and post-treatment effects of carbamazepine and vinpocetine on hearing loss and seizures induced by 4-aminopyridine.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20081101
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Neuropharmacology.
Indian journal of pharmacology 20081001
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Phosphodiesterase isozymes involved in regulation of formula secretion in isolated mouse stomach in vitro.
The Journal of pharmacology and experimental therapeutics 20080901
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Muscarinic receptor M1 and phosphodiesterase 1 are key determinants in pulmonary vascular dysfunction following perinatal hypoxia in mice.
American journal of physiology. Lung cellular and molecular physiology 20080701
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Bi-layered self-emulsifying pellets prepared by co-extrusion and spheronization: influence of formulation variables and preliminary study on the in vivo absorption.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080601
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Optimized preparation of in situ forming microparticles for the parenteral delivery of vinpocetine.
Chemical & pharmaceutical bulletin 20080601
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Reversal of tolerance to nitroglycerin with vinpocetine: a role of calcitonin gene-related peptide.
International journal of cardiology 20080425
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Molecular pharmacology of adipocyte-secreted autotaxin.
Chemico-biological interactions 20080327
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Percutaneous permeation enhancement by terpenes: mechanistic view.
The AAPS journal 20080301
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Synthesis and evaluation of 2'-hydroxyethyl trans-apovincaminate derivatives as antioxidant and cognitive enhancer agents.
Journal of medicinal chemistry 20080214
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Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Journal of medicinal chemistry 20080124
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Vinpocetine for acute ischaemic stroke.
The Cochrane database of systematic reviews 20080123
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Functional neuroimaging in multiple sclerosis with radiolabelled glia markers: preliminary comparative PET studies with [11C]vinpocetine and [11C]PK11195 in patients.
Journal of the neurological sciences 20080115
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Changes at the focus of experimental ischemic stroke treated with neuroprotective agents.
Neuroscience and behavioral physiology 20080101
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Self-microemulsifying drug delivery system (SMEDDS) of vinpocetine: formulation development and in vivo assessment.
Biological & pharmaceutical bulletin 20080101
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Mitigation of nociception via transganglionic degenerative atrophy: possible mechanism of vinpocetine-induced blockade of retrograde axoplasmic transport.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 20080101
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[Diagnostics and treatment tactics for chronic cerebrovascular disorders with the use of single photon emission computed tomography].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101
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Multimodal therapy for chronic tinnitus.
The international tinnitus journal 20080101
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[The use of vinpotropile in chronic brain ishemia].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101
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In vitro antioxidant properties of pentoxifylline and vinpocetine in a rheological model.
Clinical hemorheology and microcirculation 20080101
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[Effect of vasoactive drugs on visual functions and ocular hemodynamics in patients with primary open-angle glaucoma].
Vestnik oftalmologii 20080101
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[Cavinton administration in hypertensive encephalopathy].
Terapevticheskii arkhiv 20080101
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[The results of clinical study of cavinton efficacy inpatients with chronic brain ischemia].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101
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Development and Validation of RP-HPLC Method for Simultaneous Estimation of Atorvastatin Calcium and Fenofibrate in Tablet Dosage Forms.
Indian journal of pharmaceutical sciences 20080101
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Effects of carbamazepine, phenytoin, valproic acid, oxcarbazepine, lamotrigine, topiramate and vinpocetine on the presynaptic Ca2+ channel-mediated release of [3H]glutamate: comparison with the Na+ channel-mediated release.
Neuropharmacology 20071201
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Vinpocetine ameliorates acute hepatic damage caused by administration of carbon tetrachloride in rats.
Acta biologica Hungarica 20071201
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Phosphodiesterase isozymes involved in regulation of HCO3- secretion in isolated mouse duodenum in vitro.
Biochemical pharmacology 20071115
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Application of a novel approach to prepare biodegradable polylactic-co-glycolic acid microspheres: surface liquid spraying.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20071101
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Characterization of inhibitors of phosphodiesterase 1C on a human cellular system.
The FEBS journal 20070901
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Cyclodextrin multicomponent complexation and controlled release delivery strategies to optimize the oral bioavailability of vinpocetine.
Journal of pharmaceutical sciences 20070801
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In vitro and in vivo studies on the complexes of vinpocetine with hydroxypropyl-beta-cyclodextrin.
Archives of pharmacal research 20070801
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[Investigation of the effect of vinpocetine on cerebral blood flow and cognitive functions].
Ideggyogyaszati szemle 20070730
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[The role of vinpocetine in the treatment of cerebrovascular diseases based in human studies].
Orvosi hetilap 20070722
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Functional responses of isolated human seminal vesicle tissue to selective phosphodiesterase inhibitors.
Urology 20070701
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Broad spectrum neuroprotection profile of phosphodiesterase inhibitors as related to modulation of cell-cycle elements and caspase-3 activation.
Neuroscience letters 20070517
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Exogenous nitric oxide stimulated collagen type I expression and TGF-beta1 production in keloid fibroblasts by a cGMP-dependent manner.
Nitric oxide : biology and chemistry 20070301
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Effects of carbamazepine, phenytoin, lamotrigine, oxcarbazepine, topiramate and vinpocetine on Na+ channel-mediated release of [3H]glutamate in hippocampal nerve endings.
Neuropharmacology 20070201
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Acute and chronic effects of carbamazepine, phenytoin, valproate and vinpocetine on BAEP parameters and threshold in the guinea pig.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20070201
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[About cavinton therapy of the patients with brain vascular diseases].
Voenno-meditsinskii zhurnal 20070201
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Inhibitory effects of different antioxidants on hyaluronan depolymerization.
Carbohydrate research 20070115
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Effects of phosphodiesterase (PDE) inhibitors on human ether-a-go-go related gene (hERG) channel activity.
Journal of applied toxicology : JAT 20070101
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In vivo selective binding of (R)-[11C]rolipram to phosphodiesterase-4 provides the basis for studying intracellular cAMP signaling in the myocardium and other peripheral tissues.
Nuclear medicine and biology 20070101
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Effect of vinpocetine on retrograde axoplasmic transport.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 20070101
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Hemorheological efficiency of drugs, targeting on intracellular phosphodiesterase activity: in vitro study.
Clinical hemorheology and microcirculation 20070101
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[Effect of vasoactive agents on visual functions and ocular blood flow in patients with early manifestations of age-related macular degeneration].
Vestnik oftalmologii 20070101
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[Pharmacophysiotherapy in combined treatment of neurosensory hypoacusis in the presence of circulatory disorders in the vertebral arteries].
Vestnik otorinolaringologii 20070101
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[The state of cerebral blood flow in hypertensive crises and possibilities of its correction].
Kardiologiia 20070101
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[The use of the combined drug vinpotropil at early stages of cerebrovascular insufficiency].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20070101
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[The use of cavinton in patients with lacunar stroke developed against the background of diabetes mellitus and arterial hypertension].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20070101
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[Vinpotropile in the treatment of cerebral vascular diseases].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20070101
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[Implication of vinpotropile in the treatment of patients with cerebral stroke].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20070101
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Modulation of visceral nociception, inflammation and gastric mucosal injury by cinnarizine.
Drug target insights 20070101
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[Retrospective analysis of the effect of vinpocetine infusion in ophthalmologic disorders].
Orvosi hetilap 20061210
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Additive effects of antiepileptic drugs and pentylenetetrazole on hearing.
Neuroscience letters 20061009
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Tumoral calcinosis: Clinical and biochemical aspects of a patient treated with vinpocetine.
European journal of internal medicine 20061001
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[Plant metabolites as nootropics and cognitives].
Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20060901
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Solid lipid nanoparticles for enhancing vinpocetine's oral bioavailability.
Journal of controlled release : official journal of the Controlled Release Society 20060810
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Single and combined effects of carbamazepine and vinpocetine on depolarization-induced changes in Na+, Ca2+ and glutamate release in hippocampal isolated nerve endings.
Neurochemistry international 20060701
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Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
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Inhibition of phosphodiesterase 1 augments the pulmonary vasodilator response to inhaled nitric oxide in awake lambs with acute pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology 20060401
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New HPLC-MS method for quantitative determination of apovincaminic acid in human plasma.
Journal of separation science 20060201
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Determination of apovincaminic acid in human plasma by high-performance liquid chromatography using solid-phase extraction and ultraviolet detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060118
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Restoration of neuronal plasticity by a phosphodiesterase type 1 inhibitor in a model of fetal alcohol exposure.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20060118
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[The safe use of cavinton forte in discirculatory encephalopathy].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101
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Herbal medicine in the treatment of Alzheimer's disease.
American journal of Alzheimer's disease and other dementias 20060101
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[Disturbances of brain metabolism in blood circulation disorders and their correction with cavinton].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101
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[Effect of cavinton on the hemorheological parameters of chronic cerebrovascular patients].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101
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[Cavinton forte treatment of cerebral vascular insufficiency in patients with coronary heart disease and arterial hypertension].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101
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Vinpocetine and piracetam exert antinociceptive effect in visceral pain model in mice.
Pharmacological reports : PR 20060101
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[Experimental study of the efficacy of apovincaminic acid derivative on the model of reperfusive cerebral damage].
Eksperimental'naia i klinicheskaia farmakologiia 20060101
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Catharanthus roseus flower extract has wound-healing activity in Sprague Dawley rats.
BMC complementary and alternative medicine 20060101
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[Changes in the focus of experimental ischemic stroke under the influence of neuroprotective drugs].
Morfologiia (Saint Petersburg, Russia) 20060101
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[An effect of vinpocetine (cavinton) on endothelium function in patients with chronic cerebral ischemia].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101
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Increase in tumor oxygenation and potentiation of radiation effects using pentoxifylline, vinpocetine and ticlopidine hydrochloride.
Journal of radiation research 20051201
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Eburnamine derivatives and the brain.
Medicinal research reviews 20051101
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Acute and chronic effects of vinpocetine on cerebral hemodynamics and neuropsychological performance in multi-infarct patients.
Journal of clinical pharmacology 20050901
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Effects of various selective phosphodiesterase inhibitors on carbachol-induced contraction and cyclic nucleotide contents in the guinea pig gall bladder.
The Journal of veterinary medical science 20050701
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Vinpocetine blockade of sodium channels inhibits the rise in sodium and calcium induced by 4-aminopyridine in synaptosomes.
Neurochemistry international 20050601
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Spectrophotometric and liquid chromatographic determination of fenofibrate and vinpocetine and their hydrolysis products.
Farmaco (Societa chimica italiana : 1989) 20050501
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Neuroprotective activity of proproten in rats with experimental local photothrombosis of the prefrontal cortex.
Bulletin of experimental biology and medicine 20050401
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In vitro controlled release of vinpocetine-cyclodextrin-tartaric acid multicomponent complexes from HPMC swellable tablets.
Journal of controlled release : official journal of the Controlled Release Society 20050321
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[11C]vinpocetine: a prospective peripheral benzodiazepine receptor ligand for primate PET studies.
Journal of the neurological sciences 20050315
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Effects of vinpocetine on the redistribution of cerebral blood flow and glucose metabolism in chronic ischemic stroke patients: a PET study.
Journal of the neurological sciences 20050315
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[Drug therapy of female urinary incontinence].
Der Urologe. Ausg. A 20050301
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Expression and functional activity of phosphodiesterase type 5 in human and rabbit vas deferens.
Molecular human reproduction 20050201
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cAMP phosphodiesterase inhibitors potentiate effects of prostacyclin analogs in hypoxic pulmonary vascular remodeling.
American journal of physiology. Lung cellular and molecular physiology 20050101
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Multicomponent complex formation between vinpocetine, cyclodextrins, tartaric acid and water-soluble polymers monitored by NMR and solubility studies.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050101
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Pharmacokinetics and comparative bioavailability of two vinpocetine tablet formulations in healthy volunteers by using the metabolite apovincaminic acid as pharmacokinetic parameter.
Arzneimittel-Forschung 20050101
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Vinpocetine prevents 4-aminopyridine-induced changes in the EEG, the auditory brainstem responses and hearing.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20041201
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Review of phosphodiesterases in the urogenital system: new directions for therapeutic intervention.
The journal of sexual medicine 20041101
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Effects of various selective phosphodiesterase inhibitors on carbachol-induced contraction and cyclic nucleotide contents in guinea pig taenia coli.
The Journal of veterinary medical science 20040901
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[Optimization of microemulsion containing vinpocetine and its physicochemical properties].
Yao xue xue bao = Acta pharmaceutica Sinica 20040901
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Phosphodiesterase inhibition by a gastroprotective agent irsogladine: preferential blockade of cAMP hydrolysis.
Life sciences 20040827
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Cyclic nucleotide-dependent phosphodiesterases (PDEI) inhibition by muscarinic antagonists in bovine tracheal smooth muscle.
Biochemical pharmacology 20040815
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The effect of citric acid added to hydroxypropyl methylcellulose (HPMC) matrix tablets on the release profile of vinpocetine.
Drug development and industrial pharmacy 20040701
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Preparation, evaluation, and NMR characterization of vinpocetine microemulsion for transdermal delivery.
Drug development and industrial pharmacy 20040701
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Vinpocetine inhibits the epileptic cortical activity and auditory alterations induced by pentylenetetrazole in the guinea pig in vivo.
Epilepsy research 20040601
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Preparation and evaluation of microemulsion of vinpocetine for transdermal delivery.
Die Pharmazie 20040401
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Identification, characterization and subcellular localization of TcPDE1, a novel cAMP-specific phosphodiesterase from Trypanosoma cruzi.
The Biochemical journal 20040215
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Neuroprotection in ischemic/hypoxic disorders: from the preclinical to the clinical testing.
Advances in experimental medicine and biology 20040101
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[Use of cavinton in neuropaediatrics].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101
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[Human positron emission tomography with oral 11C-vinpocetine].
Orvosi hetilap 20031116
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Physicochemical investigation of the effects of water-soluble polymers on vinpocetine complexation with beta-cyclodextrin and its sulfobutyl ether derivative in solution and solid state.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20031101
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Vinpocetine is a potent blocker of rat NaV1.8 tetrodotoxin-resistant sodium channels.
The Journal of pharmacology and experimental therapeutics 20030801
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Investigation and physicochemical characterization of vinpocetine-sulfobutyl ether beta-cyclodextrin binary and ternary complexes.
Chemical & pharmaceutical bulletin 20030801
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Asymptomatic ischemic cerebrovascular disorders and neuroprotection with vinpocetine.
Ideggyogyaszati szemle 20030520
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[Effect of vinpocetin on the hemorheologic parameters in patients with chronic cerebrovascular disease].
Orvosi hetilap 20030518
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Lipophilicity of vinpocetine and related compounds characterized by reversed-phase thin-layer chromatography.
Journal of chromatography. A 20030509
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The lowdown on Ginkgo biloba.
Scientific American 20030401
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Large-conductance Ca2+- activated K+ channels:physiological role and pharmacology.
Current medicinal chemistry 20030401
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[Myogenic effects of cyclic guanosine monophosphate in smooth muscle cells. Role of protein kinase C].
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20030401
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Localization of cyclic nucleotide phosphodiesterase 2 in the brain-derived Triton-insoluble low-density fraction (raft).
Neuroscience research 20030201
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A vinca alkaloid enhances morphological dynamics of dendritic spines of neocortical layer 2/3 pyramidal cells.
Brain research bulletin 20030115
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Implication of calmodulin-dependent phosphodiesterase type 1 during bovine sperm capacitation.
Journal of andrology 20030101
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Vinpocetine for cognitive impairment and dementia.
The Cochrane database of systematic reviews 20030101
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Cyclic AMP-mediated regulation of striatal glutamate release: interactions of presynaptic ligand- and voltage-gated ion channels and G-protein-coupled receptors.
Neurochemistry international 20030101
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[Cavinton prevention of neurosensory hypoacousis in patients with different forms of tuberculosis].
Vestnik otorinolaringologii 20030101
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[Studying cGMP-dependent mechanisms of vinpocetine effect on smooth muscle cells].
Eksperimental'naia i klinicheskaia farmakologiia 20030101
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[Blood flow insufficiency in vertebrobasilar system].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20030101
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'Brain-specific' nutrients: a memory cure?
Nutrition (Burbank, Los Angeles County, Calif.) 20030101
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[Effect of vinpocetine on cerebral circulation in rats after exposure to radiation].
Eksperimental'naia i klinicheskaia farmakologiia 20030101
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[Memory and potassium channels].
Uspekhi fiziologicheskikh nauk 20030101
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[Use of instenon in complex treatment of patients with optic nerve atrophy caused by craniocerebral trauma].
Vestnik oftalmologii 20030101
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[Neuroprotection strategies: effect of vinpocetine in vitro oxidative stress models].
Acta medica portuguesa 20030101
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PET studies on the brain uptake and regional distribution of [11C]vinpocetine in human subjects.
Acta neurologica Scandinavica 20021201
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[Cerebral uptake and regional distribution of [11C]-vinpocetin after intravenous administration to healthy men: a PET study].
Orvosi hetilap 20021124
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Clinical and non-clinical investigations using positron emission tomography, near infrared spectroscopy and transcranial Doppler methods on the neuroprotective drug vinpocetine: a summary of evidences.
Journal of the neurological sciences 20021115
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Cerebral uptake of [ethyl-11C]vinpocetine and 1-[11C]ethanol in cynomolgous monkeys: a comparative preclinical PET study.
Nuclear medicine and biology 20021001
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Selective suppression of the slow-inactivating potassium currents by nootropics in molluscan neurons.
The international journal of neuropsychopharmacology 20020901
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Drug distribution in man: a positron emission tomography study after oral administration of the labelled neuroprotective drug vinpocetine.
European journal of nuclear medicine and molecular imaging 20020801
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The effect of phosphodiesterase inhibition on gallbladder motility in vitro.
The Journal of surgical research 20020615
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Vinpocetine increases cerebral blood flow and oxygenation in stroke patients: a near infrared spectroscopy and transcranial Doppler study.
European journal of ultrasound : official journal of the European Federation of Societies for Ultrasound in Medicine and Biology 20020601
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Relationship between bicarbonate and cyclic nucleotide in the promoting effects on head-to-head agglutination in boar spermatozoa.
Asian journal of andrology 20020601
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Vinpocetine. Monograph.
Alternative medicine review : a journal of clinical therapeutic 20020601
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Functional plasticity of cyclic AMP hydrolysis in rat adenohypophysial corticotroph cells.
Cellular signalling 20020501
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Piracetam and vinpocetine exert cytoprotective activity and prevent apoptosis of astrocytes in vitro in hypoxia and reoxygenation.
Neurotoxicology 20020501
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Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
The Journal of biological chemistry 20020419
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Phosphodiesterase inhibitors cause relaxation of the internal anal sphincter in vitro.
Diseases of the colon and rectum 20020401
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[Scavenger effect of various cerebrovascular drugs].
Orvosi hetilap 20020106
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Assessing the emetic potential of PDE4 inhibitors in rats.
British journal of pharmacology 20020101
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Cyclic nucleotide phosphodiesterases in rabbit detrusor smooth muscle.
Urology 20020101
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In vitro antioxidant properties of pentoxifylline, piracetam, and vinpocetine.
Clinical neuropharmacology 20020101
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Modulation of TNF and GM-CSF release from dispersed human nasal polyp cells and human whole blood by inhibitors of different PDE isoenzymes and glucocorticoids.
Pulmonary pharmacology & therapeutics 20020101
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Autoradiographic evaluation of [11C]vinpocetine binding in the human postmortem brain.
Acta biologica Hungarica 20020101
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Effect of inhibitors of cyclic nucleotide phosphodiesterases on electrical and contractile activity of smooth muscle cells.
Bulletin of experimental biology and medicine 20020101
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[Investigation of vasoactive agents with indole skeletons at Richter Ltd].
Acta pharmaceutica Hungarica 20020101
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[Neuroprotective effects of vinpocetine in vivo and in vitro. Apovincaminic acid derivatives as potential therapeutic tools in ischemic stroke].
Acta pharmaceutica Hungarica 20020101
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Characterization and functional relevance of cyclic nucleotide phosphodiesterase isoenzymes of the human prostate.
The Journal of urology 20011201
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Identification and functional study of phosphodiesterases in rat urinary bladder.
Urological research 20011201
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Upregulation of phosphodiesterase 1A1 expression is associated with the development of nitrate tolerance.
Circulation 20011106
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Phosphodiesterase 1 inhibition in the treatment of lower urinary tract dysfunction: from bench to bedside.
World journal of urology 20011101
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The nootropic drug vinpocetine inhibits veratridine-induced [Ca2+]i increase in rat hippocampal CA1 pyramidal cells.
Neurochemical research 20010901
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Characterization of vinpocetine effects on DA and DOPAC release in striatal isolated nerve endings.
Brain research 20010803
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Ibudilast attenuates astrocyte apoptosis via cyclic GMP signalling pathway in an in vitro reperfusion model.
British journal of pharmacology 20010701
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Characterization of r-[11C]rolipram for PET imaging of phosphodieterase-4: in vivo binding, metabolism, and dosimetry studies in rats.
Nuclear medicine and biology 20010501
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Vinpocetine-induced stimulation of calcium-activated potassium currents in rat pituitary GH3 cells.
Biochemical pharmacology 20010401
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[The effect of a single-dose intravenous vinpocetine on brain metabolism in patients with ischemic stroke].
Orvosi hetilap 20010304
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[The use of vinpocetine in chronic disorders caused by cerebral hypoperfusion].
Orvosi hetilap 20010225
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The nootropic drug vinpocetine modulates different types of potassium currents in molluscan neurons.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010201
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The effects of phosphodiesterase inhibition on cyclic GMP and cyclic AMP accumulation in the hippocampus of the rat.
Brain research 20010112
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Dependence of soluble guanylyl cyclase activity on calcium signaling in pituitary cells.
The Journal of biological chemistry 20010105
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Vinpocetine treatment in acute ischaemic stroke: a pilot single-blind randomized clinical trial.
European journal of neurology 20010101
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[Cavinton in epilepsy treatment and prevention].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20010101
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[Complex effects of cavinton on climacteric symptoms].
Akusherstvo i ginekologiia 20010101
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In vitro-in vivo correlation of the pharmacokinetics of vinpocetine.
Polish journal of pharmacology 20010101
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Identification of human PDE7B, a cAMP-specific phosphodiesterase.
Biochemical and biophysical research communications 20000519
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Isolation and characterization of cDNAs corresponding to two human calcium, calmodulin-regulated, 3',5'-cyclic nucleotide phosphodiesterases.
The Journal of biological chemistry 19960112
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Cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human detrusor smooth muscle. II. Effect of various PDE inhibitors on smooth muscle tone and cyclic nucleotide levels in vitro.
Urological research 19960101
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Effects of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle.
Biochemical pharmacology 19840201
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The synthesis of ethyl apovincaminate.
Arzneimittel-Forschung 19760101