438190-29-5 | SMI 4A

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$43.00	$30.00
5mg	≥98%	in stock	$83.00	$58.00
10mg	≥98%	in stock	$129.00	$90.00
50mg	98%	in stock	$234.00	$164.00
1g	98%	in stock	$1,139.00	$798.00

Description

• Catalog Number: AD30416
• Chemical Name: SMI 4A
• CAS Number: 438190-29-5
• Molecular Formula: C11H6F3NO2S
• Molecular Weight: 273.2310
• MDL Number: MFCD01152003
• SMILES: O=C1NC(=O)/C(=C/c2cccc(c2)C(F)(F)F)/S1

Computed Properties

• Complexity: 406
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 3.1

Literature

• Potential use of selective and nonselective Pim kinase inhibitors for cancer therapy.

  Journal of medicinal chemistry 20121011

• Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases.

  Journal of medicinal chemistry 20090108

• In vitro antiproliferative activity against human colon cancer cell lines of representative 4-thiazolidinones. Part I.

  Bioorganic & medicinal chemistry letters 20050901