4382-54-1 | 5-Methoxyindole-2-carboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$16.00	$11.00
1g	95%	in stock	$19.00	$13.00
5g	95%	in stock	$23.00	$16.00
10g	95%	in stock	$30.00	$21.00
25g	95%	in stock	$66.00	$46.00
100g	95%	in stock	$256.00	$179.00

Description

• Catalog Number: AB69373
• Chemical Name: 5-Methoxyindole-2-carboxylic acid
• CAS Number: 4382-54-1
• Molecular Formula: C10H9NO3
• Molecular Weight: 191.1834
• MDL Number: MFCD00005614
• SMILES: COc1ccc2c(c1)cc([nH]2)C(=O)O
• NSC Number: 30927

Computed Properties

• Complexity: 231
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 2.3

Literature

• Association of lactate, intracellular pH, and intracellular calcium during capacitation and acrosome reaction: contribution of hamster sperm dihydrolipoamide dehydrogenase, the E3 subunit of pyruvate dehydrogenase complex.

  Journal of andrology 20120101

• New spectrofluorimetric methods for determination of melatonin in the presence of N-{2-[1-({3-[2-(acetylamino)ethyl]-5-methoxy-1H-indol-2-yl}methyl)-5-methoxy-1H-indol-3-yl]- ethyl}acetamide: a contaminant in commercial melatonin preparations.

  Chemistry Central journal 20120101

• 1,3-Dinitrobenzene-induced metabolic impairment through selective inactivation of the pyruvate dehydrogenase complex.

  Toxicological sciences : an official journal of the Society of Toxicology 20110801

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Vibrational spectroscopic studies of indolecarboxylic acids and their metal complexes part VIII. 5-methoxyindole-2-carboxylic acid and its Zn(II) complex.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090301

• Hamster sperm capacitation: role of pyruvate dehydrogenase A and dihydrolipoamide dehydrogenase.

  Biology of reproduction 20080801

• Non-peptidic small-molecule inhibitors of the single-chain hepatitis C virus NS3 protease/NS4A cofactor complex discovered by structure-based NMR screening.

  Journal of medicinal chemistry 20040506

• Novel tyrosine-phosphorylated post-pyruvate metabolic enzyme, dihydrolipoamide dehydrogenase, involved in capacitation of hamster spermatozoa.

  Biology of reproduction 20040401