4551-72-8 | 1H-Pyrrole-2-carboxamide

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$48.00	$34.00
1g	95%	in stock	$71.00	$50.00
5g	95%	in stock	$244.00	$171.00
100g	95%	in stock	$3,277.00	$2,294.00

Description

• Catalog Number: AG19724
• Chemical Name: 1H-Pyrrole-2-carboxamide
• CAS Number: 4551-72-8
• Molecular Formula: C5H6N2O
• Molecular Weight: 110.1139
• MDL Number: MFCD00273121
• SMILES: NC(=O)c1ccc[nH]1

Computed Properties

• Complexity: 103
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 0.2

Literature

• The trifluoromethyl transformation synthesis, crystal structure and insecticidal activities of novel 2-pyrrolecarboxamide and 2-pyrrolecarboxlate.

  Bioorganic & medicinal chemistry letters 20121115

• A sweet origin for the key congocidine precursor 4-acetamidopyrrole-2-carboxylate.

  Angewandte Chemie (International ed. in English) 20120723

• The discovery and initial optimisation of pyrrole-2-carboxamides as inhibitors of p38alpha MAP kinase.

  Bioorganic & medicinal chemistry letters 20100701

• Visual responses in mice lacking critical components of all known retinal phototransduction cascades.

  PloS one 20100101

• Synthesis, Binding and Fluorescence Studies of Bis-2-amidopyrrole Receptors for Bis-carboxylate Anions.

  Sensors (Basel, Switzerland) 20090101

• Structurally unique inhibitors of human mitogen-activated protein kinase phosphatase-1 identified in a pyrrole carboxamide library.

  The Journal of pharmacology and experimental therapeutics 20070901

• Novel inhibitors of VEGF receptors-1 and -2 based on azole-5-carboxamide templates.

  Bioorganic & medicinal chemistry letters 20070701

• Heteronuclear intermolecular resonance-assisted hydrogen bonds. The structure of pyrrole-2-carboxamide (PyCa).

  The journal of physical chemistry. B 20060330

• Solution-phase synthesis of a tricyclic pyrrole-2-carboxamide discovery library applying a stetter-Paal-Knorr reaction sequence.

  Journal of combinatorial chemistry 20060101

• Novel non-steroidal/non-anilide type androgen antagonists: discovery of 4-substituted pyrrole-2-carboxamides as a new scaffold for androgen receptor ligands.

  Bioorganic & medicinal chemistry 20050415