482-44-0 | Imperatorin

Packsize	Purity	Availability	Price	Discounted Price
1mg	97%	in stock	$9.00	$6.00
10mg	97%	in stock	$22.00	$16.00
250mg	97%	in stock	$103.00	$72.00
1g	97%	in stock	$253.00	$177.00

Description

• Catalog Number: AI50974
• Chemical Name: Imperatorin
• CAS Number: 482-44-0
• Molecular Formula: C16H14O4
• Molecular Weight: 270.2800
• MDL Number: MFCD00016881
• SMILES: CC(=CCOc1c2occc2cc2c1oc(=O)cc2)C
• NSC Number: 402949

Computed Properties

• Complexity: 436
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• XLogP3: 3.4

Literature

• The imperatorin derivative OW1, a new vasoactive compound, inhibits VSMC proliferation and extracellular matrix hyperplasia.

  Toxicology and applied pharmacology 20150415

• Simultaneous determination of imperatorin and its 2 metabolites in dog plasma by using liquid chromatography-tandem mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20121101

• Cell death in HeLa cells upon imperatorin and cisplatin treatment.

  Folia histochemica et cytobiologica 20121008

• Bioactive constituents of Clausena lansium and a method for discrimination of aldose enantiomers.

  Phytochemistry 20121001

• The effects of imperatorin on anxiety and memory-related behavior in male Swiss mice.

  Experimental and clinical psychopharmacology 20120801

• Simultaneous determination of six active components in traditional herbal medicine 'Oyaksungisan' by HPLC-DAD.

  Journal of natural medicines 20120701

• Larvicidal activity of Cnidium monnieri fruit coumarins and structurally related compounds against insecticide-susceptible and insecticide-resistant Culex pipiens pallens and Aedes aegypti.

  Pest management science 20120701

• [Study on absorption ingredients of yuanhuzhitong pill by everted intestinal sac method].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120701

• Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13.

  Bioorganic & medicinal chemistry letters 20120615

• Pressurized liquid extraction of coumarins from fruits of Heracleum leskowii with application of solvents with different polarity under increasing temperature.

  Molecules (Basel, Switzerland) 20120405

• [Simultaneous determination of three coumarins in Angelica dahurica var. formosana by QAMS].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120401

• New biological activities of Casimiroa edulis leaf extract and isolated compounds.

  Phytotherapy research : PTR 20120301

• Simultaneous analysis of six major compounds in Osterici Radix and Notopterygii Rhizoma et Radix by HPLC and discrimination of their origins from chemical fingerprint analysis.

  Archives of pharmacal research 20120301

• Furocoumarins affect hepatic cytochrome P450 and renal organic ion transporters in mice.

  Toxicology letters 20120225

• Inducible nitric oxide synthase and cyclooxygenase-2 participate in anti-inflammatory activity of imperatorin from Glehnia littoralis.

  Journal of agricultural and food chemistry 20120222

• Hepatoprotective activity of Cyperus alternifolius on carbon tetrachloride-induced hepatotoxicity in rats.

  Pharmaceutical biology 20120201

• Structure-activity relationships for naturally occurring coumarins as β-secretase inhibitor.

  Bioorganic & medicinal chemistry 20120115

• Development of a rapid resolution liquid chromatographic method combined with chemometrics for quality control of Angelicae dahuricae radix.

  Phytochemical analysis : PCA 20120101

• Imperatorin prevents cardiac hypertrophy and the transition to heart failure via NO-dependent mechanisms in mice.

  Fitoterapia 20120101

• Main constituents from the seeds of Vietnamese Cnidium monnieri and cytotoxic activity.

  Natural product research 20120101

• F420H2-dependent degradation of aflatoxin and other furanocoumarins is widespread throughout the actinomycetales.

  PloS one 20120101

• Angelicae Dahuricae Radix Inhibits Dust Mite Extract-Induced Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice.

  Evidence-based complementary and alternative medicine : eCAM 20120101

• Geographical variation of the furanocoumarin composition of the fruits of Icelandic Angelica archangelica.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20120101

• An overview of the evidence and mechanisms of herb-drug interactions.

  Frontiers in pharmacology 20120101

• Quantitative NMR: an applicable method for quantitative analysis of medicinal plant extracts and herbal products.

  Phytochemical analysis : PCA 20120101

• Imperatorin a furocoumarin inhibits periplasmic Cu-Zn SOD of Shigella dysenteriae their by modulates its resistance towards phagocytosis during host pathogen interaction.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20111201

• Fatty acids as natural specific inhibitors of the proto-oncogenic protein Shp2.

  Bioorganic & medicinal chemistry letters 20111115

• Simultaneous quantification of 17 constituents from Yuanhu Zhitong tablet using rapid resolution liquid chromatography coupled with a triple quadrupole electrospray tandem mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20111101

• A potential calcium antagonist and its antihypertensive effects.

  Fitoterapia 20111001

• Distinct effects of imperatorin on allergic rhinitis: imperatorin inhibits caspase-1 activity in vivo and in vitro.

  The Journal of pharmacology and experimental therapeutics 20111001

• Insights into structure-activity relationship of GABAA receptor modulating coumarins and furanocoumarins.

  European journal of pharmacology 20111001

• Antigenotoxic activity of naturally occurring furanocoumarins.

  Environmental and molecular mutagenesis 20111001

• Effects of furanocoumarins from apiaceous vegetables on the catalytic activity of recombinant human cytochrome P-450 1A2.

  The protein journal 20111001

• Simultaneous determination of chromones and coumarins in Radix Saposhnikoviae by high performance liquid chromatography with diode array and tandem mass detectors.

  Journal of chromatography. A 20110916

• Bioactivity-guided fractionation for the butyrylcholinesterase inhibitory activity of furanocoumarins from Angelica archangelica L. roots and fruits.

  Journal of agricultural and food chemistry 20110914

• [Component difference of herb materials extracts with sesame oil fry and SFE-CO2 technique for compound ulcer oil].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110901

• Quantitative analysis of nine coumarins in rat urine and bile after oral administration of Radix Glehniae extract by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry.

  Biomedical chromatography : BMC 20110701

• Identification of ostruthin from Peucedanum ostruthium rhizomes as an inhibitor of vascular smooth muscle cell proliferation.

  Journal of natural products 20110624

• Development of a high throughput screen for allosteric modulators of melanocortin-4 receptor signaling using a real time cAMP assay.

  European journal of pharmacology 20110611

• [Determination of supermolecular inclusion constants of hydroxylpropyl-beta-cylcodextrin with imperatorin and isoimperatorin by phase solubility method].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110601

• Identification and quantification of coumarins in Peucedanum ostruthium (L.) Koch by HPLC-DAD and HPLC-DAD-MS.

  Journal of agricultural and food chemistry 20110511

• [Determination of imperatorin and isoimperatorin in cosmetics by high performance liquid chromatography-tandem mass spectrometry].

  Se pu = Chinese journal of chromatography 20110501

• Antifibrotic activity of coumarins from Cnidium monnieri fruits in HSC-T6 hepatic stellate cells.

  Journal of natural medicines 20110401

• HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes.

  Fitoterapia 20110401

• A substrate-specific cytochrome P450 monooxygenase, CYP6AB11, from the polyphagous navel orangeworm (Amyelois transitella).

  Insect biochemistry and molecular biology 20110401

• Potential of Complementary and Alternative Medicine in Preventive Management of Novel H1N1 Flu (Swine Flu) Pandemic: Thwarting Potential Disasters in the Bud.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• Design, synthesis and preliminary evaluation of novel imperatorin derivatives as vasorelaxant agents.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20110101

• Anti-influenza activity of marchantins, macrocyclic bisbibenzyls contained in liverworts.

  PloS one 20110101

• Effect of herbal extract granules combined with probiotic mixture on irritable bowel syndrome with diarrhea: study protocol for a randomized controlled trial.

  Trials 20110101

• Stimulation of Airway and Intestinal Mucosal Secretion by Natural Coumarin CFTR Activators.

  Frontiers in pharmacology 20110101

• Anticancer effects of imperatorin isolated from Angelica dahurica: induction of apoptosis in HepG2 cells through both death-receptor- and mitochondria-mediated pathways.

  Chemotherapy 20110101

• Sulfur fumigation processing of traditional chinese medicinal herbs: beneficial or detrimental?

  Frontiers in pharmacology 20110101

• Furanocoumarins-imperatorin inhibits myocardial hypertrophy both in vitro and in vivo.

  Fitoterapia 20101201

• [Quantitative determination of six coumarins in Angelica dahurica var. formosana by RRLC-UV].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101201

• Role of store-operated calcium entry in imperatorin-induced vasodilatation of rat small mesenteric artery.

  European journal of pharmacology 20101125

• Photoionization of psoralen derivatives in micelles: Imperatorin and alloimperatorin.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20101101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• [Dynamic research of growth, N, P, K and active ingredients in Angelica dahurica var. formosana from Sichuan province].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101101

• Imperatorin sustained-release tablets: In vitro and pharmacokinetic studies.

  Archives of pharmacal research 20100801

• On-line concentration by field-enhanced sample injection with reverse migrating micelles in micellar electrokinetic capillary chromatography for the analysis of coumarins from traditional Chinese medicine and human serum.

  Biomedical chromatography : BMC 20100601

• [Chemical constituents of roots of Saposhnikovia divaricata].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100601

• Osthole or imperatorin-mediated facilitation of glutamate release is associated with a synaptic vesicle mobilization in rat hippocampal glutamatergic nerve endings.

  Synapse (New York, N.Y.) 20100501

• beta-secretase inhibitory effects of furanocoumarins from the root of Angelica dahurica.

  Phytotherapy research : PTR 20100401

• Fast separation and determination of coumarins in Fructus cnidii extracts by CEC using poly(butyl methacrylate-co-ethylene dimethacrylate-co-[2-(methacryloyloxy)ethyl] trimethylammonium chloride) monolithic columns.

  Journal of separation science 20100401

• Antimicrobial coumarins from the stem bark of Afraegle paniculata.

  Natural product communications 20100401

• [Fast determination of active components in Angelica dahurica extract using capillary electrochromatography with methacrylate ester-based monolithic columns].

  Se pu = Chinese journal of chromatography 20100301

• Antifungal constituents isolated from the seeds of Aegle marmelos.

  Phytochemistry 20100201

• Inhibitory effects of polyphenols on human cytochrome P450 3A4 and 2C9 activity.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

• Biotransformation of isoimperatorin and imperatorin by Glomerella cingulata and beta-secretase inhibitory activity.

  Bioorganic & medicinal chemistry 20100101

• Novel enoyl-ACP reductase (FabI) potential inhibitors of Escherichia coli from Chinese medicine monomers.

  Bioorganic & medicinal chemistry letters 20100101

• Differentiation of four pairs of furocoumarin isomers by electrospray ionization tandem mass spectrometry.

  European journal of mass spectrometry (Chichester, England) 20100101

• [Chemical constituents of Incarvillea younghusbandii].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100101

• [Study on the content of imperatorin and HPLC fingerprint of Baizhi collected from different areas].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100101

• Rapid identification of furanocoumarins in Angelica dahurica using the online LC-MMR-MS and their nitric oxide inhibitory activity in RAW 264.7 cells.

  Phytochemical analysis : PCA 20100101

• A Validated RP HPLC-PAD Method for the Determination of Hederacoside C in Ivy-Thyme Cough Syrup.

  International journal of analytical chemistry 20100101

• An efficient strategy based on MAE, HPLC-DAD-ESI-MS/MS and 2D-prep-HPLC-DAD for the rapid extraction, separation, identification and purification of five active coumarin components from Radix Angelicae Dahuricae.

  Phytochemical analysis : PCA 20100101

• Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene.

  BMC cancer 20100101

• Evaluation of Antiseizure Activity of Essential Oil from Roots of Angelica archangelica Linn. in Mice.

  Indian journal of pharmaceutical sciences 20100101

• Anticonvulsant effects of four linear furanocoumarins, bergapten, imperatorin, oxypeucedanin, and xanthotoxin, in the mouse maximal electroshock-induced seizure model: a comparative study.

  Pharmacological reports : PR 20100101

• Psoralea corylifolia Linn.-'Kushtanashini'.

  Pharmacognosy reviews 20100101

• Separation and determination of coumarins in Fructus cnidii extracts by pressurized capillary electrochromatography using a packed column with a monolithic outlet frit.

  Journal of pharmaceutical and biomedical analysis 20091205

• Imperatorin is responsible for the vasodilatation activity of Angelica Dahurica var. Formosana regulated by nitric oxide in an endothelium-dependent manner.

  Chinese journal of integrative medicine 20091201

• A vascular smooth muscle/cell membrane chromatography-offline-gas chromatography/mass spectrometry method for recognition, separation and identification of active components from traditional Chinese medicines.

  Journal of chromatography. A 20091016

• Simultaneous determination of five coumarins in Angelicae dahuricae Radix by HPLC/UV and LC-ESI-MS/MS.

  Biomedical chromatography : BMC 20091001

• Natural coumarins as a novel class of neuroprotective agents.

  Mini reviews in medicinal chemistry 20091001

• Anticonvulsant and acute neurotoxic effects of imperatorin, osthole and valproate in the maximal electroshock seizure and chimney tests in mice: a comparative study.

  Epilepsy research 20090801

• Coumarins from Angelica lucida L.--antibacterial activities.

  Molecules (Basel, Switzerland) 20090727

• Development and validation of a gas chromatography-mass spectrometry method for the determination of imperatorin in rat plasma and tissue: application to study its pharmacokinetics.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090701

• [Effect of Chuanxiong Fangfeng Baizhi prescription on isolated rabbit basilar artery].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090601

• Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice.

  Toxicology letters 20090328

• Pharmacological properties of the extract and some isolated compounds of Clausena lansium stem bark: anti-trichomonal, antidiabetic, anti-inflammatory, hepatoprotective and antioxidant effects.

  Journal of ethnopharmacology 20090225

• Identification and quantification of the volatile constituents in Cnidium monnieri using supercritical fluid extraction followed by GC-MS.

  Journal of separation science 20090101

• Citrus auraptene suppresses cyclin D1 and significantly delays N-methyl nitrosourea induced mammary carcinogenesis in female Sprague-Dawley rats.

  BMC cancer 20090101

• Novel inhibitors of the calcineurin/NFATc hub - alternatives to CsA and FK506?

  Cell communication and signaling : CCS 20090101

• Osthole and imperatorin, the active constituents of Cnidium monnieri (L.) Cusson, facilitate glutamate release from rat hippocampal nerve terminals.

  Neurochemistry international 20081201

• Effects of naturally occurring coumarins on hepatic drug-metabolizing enzymes in mice.

  Toxicology and applied pharmacology 20081015

• Supercritical fluid extraction for identification and determination of volatile metabolites from Angelica dahurica by GC-MS.

  Journal of separation science 20081001

• Lead compounds for anti-inflammatory drugs isolated from the plants of the traditional oriental medicine in Korea.

  Inflammation & allergy drug targets 20080901

• Identification of natural coumarin compounds that rescue defective DeltaF508-CFTR chloride channel gating.

  Clinical and experimental pharmacology & physiology 20080801

• Micelle-mediated extraction and cloud-point preconcentration of osthole and imperatorin from Cnidium monnieri with analysis by high performance liquid chromatography.

  Journal of chromatography. A 20080725

• Simultaneous determination of 10 active components in traditional Chinese medicine 'YIGONG' capsule by RP-HPLC-DAD.

  Journal of pharmaceutical and biomedical analysis 20080609

• Metabolism of myristicin by Depressaria pastinacella CYP6AB3v2 and inhibition by its metabolite.

  Insect biochemistry and molecular biology 20080601

• Nematicidal coumarins from Heracleum candicans Wall.

  Natural product research 20080520

• Enhancement of bone morphogenetic protein-2 expression and bone formation by coumarin derivatives via p38 and ERK-dependent pathway in osteoblasts.

  European journal of pharmacology 20080128

• Real-time fluorescence-based detection of furanocoumarin photoadducts of DNA.

  Phytochemical analysis : PCA 20080101

• Influence of imperatorin on the anticonvulsant activity and acute adverse-effect profile of lamotrigine in maximal electroshock-induced seizures and chimney test in mice.

  Pharmacological reports : PR 20080101

• Imperatorin enhances the protective activity of conventional antiepileptic drugs against maximal electroshock-induced seizures in mice.

  European journal of pharmacology 20071128

• Imperatorin induces vasodilatation possibly via inhibiting voltage dependent calcium channel and receptor-mediated Ca2+ influx and release.

  European journal of pharmacology 20071114

• Time-course and dose-response relationships of imperatorin in the mouse maximal electroshock seizure threshold model.

  Neuroscience research 20070901

• [Simultaneous determination of 5 active components in Fructus Cnidii by HPLC].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070901

• Effect of chrysin and natural coumarins on UGT1A1 and 1A6 activities in rat and human hepatocytes in primary culture.

  Planta medica 20070701

• [Studies on chemical constituents in fruit of Gardenia jasminoides].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070601

• High-performance liquid chromatographic method for the determination and pharmacokinetic study of oxypeucedanin hydrate and byak-angelicin after oral administration of Angelica dahurica extracts in mongrel dog plasma.

  Journal of pharmaceutical and biomedical analysis 20070509

• Allelic variation in the Depressaria pastinacella CYP6AB3 protein enhances metabolism of plant allelochemicals by altering a proximal surface residue and potential interactions with cytochrome P450 reductase.

  The Journal of biological chemistry 20070406

• Ethyl acetate extract from Angelica Dahuricae Radix inhibits lipopolysaccharide-induced production of nitric oxide, prostaglandin E2 and tumor necrosis factor-alphavia mitogen-activated protein kinases and nuclear factor-kappaB in macrophages.

  Pharmacological research 20070401

• Antiproliferative effect of furanocoumarins from the root of Angelica dahurica on cultured human tumor cell lines.

  Phytotherapy research : PTR 20070301

• Antitumor effects of Osthol from Cnidium monnieri: an in vitro and in vivo study.

  Phytotherapy research : PTR 20070301

• Antibacterial and anticoagulant activities of coumarins isolated from the flowers of Magydaris tomentosa.

  Planta medica 20070201

• Coumarins from Cnidium monnieri and their antiosteoporotic activity.

  Planta medica 20070101

• Ethnoveterinary medicines used for ruminants in British Columbia, Canada.

  Journal of ethnobiology and ethnomedicine 20070101

• Inhibition of acetylcholinesterase by extracts and constituents from Angelica archangelica and Geranium sylvaticum.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101

• Determination of liquiritin, naringin, hesperidin, thymol, imperatorin, honokiol, isoimperatorin, and magnolol in the traditional Chinese medicinal preparation Huoxiang-zhengqi liquid using high-performance liquid chromatography.

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20061101

• [Analysis of coumarins in Fructus Cnidii by HPLC-ESI-MS].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20061001

• [Studies on chemical constituents from roots of Peucedanum praeruptorum II].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060801

• Naturally occurring coumarins inhibit 7,12-dimethylbenz[a]anthracene DNA adduct formation in mouse mammary gland.

  Carcinogenesis 20060601

• Preparative isolation of imperatorin, oxypeucedanin and isoimperatorin from traditional Chinese herb 'bai zhi'Angelica dahurica (Fisch. ex Hoffm) Benth. et Hook using multidimensional high-speed counter-current chromatography.

  Journal of chromatography. A 20060519

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Separation and quantitative analysis of coumarin compounds from Angelica dahurica (Fisch. ex Hoffm) Benth. et Hook. f by pressurized capillary electrochromatography.

  Journal of pharmaceutical and biomedical analysis 20060411

• Remarkable substrate-specificity of CYP6AB3 in Depressaria pastinacella, a highly specialized caterpillar.

  Insect molecular biology 20060401

• Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis.

  Journal of natural products 20060401

• Determination of imperatorin in rat plasma by reversed-phase high-performance liquid chromatography after oral administration of Radix Angelicae dahuricae extract.

  Journal of pharmaceutical and biomedical analysis 20060318

• Cytochrome P450-mediated metabolism of xanthotoxin by Papilio multicaudatus.

  Journal of chemical ecology 20060301

• [Studies on chemical constituents in roots of Heracleum rapula].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060201

• New cosmetic agents for skin whitening from Angelica dahurica.

  Journal of cosmetic science 20060101

• In vitro GABA-transaminase inhibitory compounds from the root of Angelica dahurica.

  Phytotherapy research : PTR 20051001

• [Progress in study of chemical constituents and anti-tumor activities of Cnidium monnieri].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050901

• Accumulation of biologically active furanocoumarins in agitated cultures of Ruta graveolens L. and Ruta graveolens ssp. divaricata (Tenore) Gams.

  Die Pharmazie 20050801

• [Study on extraction of coumarins in Cnidium monieri by supercritical CO2 and separation of compositions analysis].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050701

• Antifungal constituents of northern prickly ash, Zanthoxylum americanum mill.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20050501

• Inhibitors of nitric oxide production from the flowers of Angelica furcijuga: structures of hyuganosides IV and V.

  Chemical & pharmaceutical bulletin 20050401

• Coumarins are competitive inhibitors of cytochrome P450 1B1, with equal potency for allelic variants.

  Pharmacogenetics and genomics 20050301

• Chemical aspects of coumarin compounds for the prevention of hepatocellular carcinomas.

  Current medicinal chemistry. Anti-cancer agents 20050101

• HPLC comparison of supercritical fluid extraction and solvent extraction of coumarins from the peel of Citrus maxima fruit.

  Phytochemical analysis : PCA 20050101

• Preparative isolation and purification of bergapten and imperatorin from the medicinal plant Cnidium monnieri using high-speed counter-current chromatography by stepwise increasing the flow-rate of the mobile phase.

  Journal of chromatography. A 20041217

• 2D NMR spectroscopic analyses of archangelicin from the seeds of Angelica archangelica.

  Acta pharmaceutica (Zagreb, Croatia) 20041201

• Imperatorin inhibits T-cell proliferation by targeting the transcription factor NFAT.

  Planta medica 20041101

• [Determination of coumarins content in Radix Angelicae dahuricae by HPLC and UV].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20041101

• Preparative isolation and purification of coumarins from Angelica dahurica (Fisch. ex Hoffn) Benth, et Hook. f (Chinese traditional medicinal herb) by high-speed counter-current chromatography.

  Journal of chromatography. A 20041015

• Imperatorin inhibits HIV-1 replication through an Sp1-dependent pathway.

  The Journal of biological chemistry 20040903

• Antioxidative activity of furanocoumarins isolated from Angelicae dahuricae.

  Journal of ethnopharmacology 20040801

• Coumarins from Cnidium monnieri (L.) and their proliferation stimulating activity on osteoblast-like UMR106 cells.

  Die Pharmazie 20040801

• [Studies on quality standards of radix Angelicae dahuricae].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040701

• Biotransformation of imperatorin by Aspergillus flavus.

  Journal of natural products 20040601

• Coumarins from Opopanax chironium. New dihydrofuranocoumarins and differential induction of apoptosis by imperatorin and heraclenin.

  Journal of natural products 20040401

• [Extraction of coumarins from Angelica dahurica by supercritical extraction and GC-MS analysis].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040301

• Antiproliferative effect of Angelica archangelica fruits.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101

• Cytotoxic activity of coumarins from the fruits of Cnidium monnieri on leukemia cell lines.

  Planta medica 20031201

• A mixed crystal of imperatorin and phellopterin, with C--H...O, C--H...pi and pi-pi interactions.

  Acta crystallographica. Section C, Crystal structure communications 20030901

• Constituents of Peucedanum zenkeri seeds and their antimicrobial effects.

  Die Pharmazie 20030801

• Inhibitory effects of furanocoumarins isolated from the roots of Angelica dahurica on prostaglandin E2 production.

  Planta medica 20030501

• Naturally occurring coumarins inhibit human cytochromes P450 and block benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene DNA adduct formation in MCF-7 cells.

  Chemical research in toxicology 20030301

• HPLC-NMR/HPLC-MS analysis of the bark extract of Stauranthus perforatus.

  Phytochemical analysis : PCA 20030101

• Acetylcholinesterase inhibitors from the roots of Angelica dahurica.

  Archives of pharmacal research 20021201

• [Study on the relativity between cultivated varieties and quality of Radix Glehniae].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20021101

• Oral administration of the citrus coumarin, isopimpinellin, blocks DNA adduct formation and skin tumor initiation by 7,12-dimethylbenz[a]anthracene in SENCAR mice.

  Carcinogenesis 20021001

• Imperatorin, a furanocoumarin from Angelica dahurica (Umbelliferae), induces cytochrome c-dependent apoptosis in human promyelocytic leukaemia, HL-60 Cells.

  Pharmacology & toxicology 20020701

• [Determination of imperatorin in tetraploidy radix Angelicae dahuricae].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20020601

• Furocoumarins from Angelica dahurica with hepatoprotective activity on tacrine-induced cytotoxicity in Hep G2 cells.

  Planta medica 20020501

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• Expression of intercellular adhesion molecule-1 in U937 foam cells and inhibitory effect of imperatorin.

  Acta pharmacologica Sinica 20020401

• Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation.

  Chemical research in toxicology 20020201

• Evaluation of synergism in the feeding deterrence of some furanocoumarins on Spodoptera littoralis.

  Journal of chemical ecology 20020101

• Epoxidation of some natural furocoumarins and furochromones using gamma-ray.

  Bollettino chimico farmaceutico 20020101

• Photosynthesis of furocoumarin- and furochromone-types potential intercalative alkylating and oxidizing agents of DNA through photooxidations using gamma-ray.

  Bollettino chimico farmaceutico 20020101

• Indolopyridoquinazoline alkaloid from Leptothyrsa sprucei.

  Phytochemistry 20011001

• A bioassay using the human hepatoblastoma cell line HepG2 for detecting phototoxicity of furocoumarins.

  Planta medica 20011001

• Inhibition of itch-scratch response by fruits of Cnidium monnieri in mice.

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