484-20-8 | Bergapten

Packsize	Purity	Availability	Price	Discounted Price
100mg	99%(GC)	in stock	$45.00	$32.00
1g	98%	in stock	$53.00	$37.00
5g	98 - 102% (HPLC)	in stock	$113.00	$79.00
25g	98 - 102% (HPLC)	in stock	$271.00	$190.00
100g	98 - 102% (HPLC)	in stock	$740.00	$518.00
250g	98 - 102% (HPLC)	in stock	$1,690.00	$1,183.00

Description

• Catalog Number: AD22281
• Chemical Name: Bergapten
• CAS Number: 484-20-8
• Molecular Formula: C12H8O4
• Molecular Weight: 216.1895
• MDL Number: MFCD00010272
• SMILES: COc1c2ccc(=O)oc2cc2c1cco2

Computed Properties

• Complexity: 325
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• XLogP3: 2.3

Literature

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  Toxicology and applied pharmacology 20171215

• The Canadian medicinal plant Heracleum maximum contains antimycobacterial diynes and furanocoumarins.

  Journal of ethnopharmacology 20130502

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  Bioorganic & medicinal chemistry 20121115

• Furanocoumarins in celeriac from different farming systems: a 3-year study.

  Journal of the science of food and agriculture 20121101

• Bergapten induces ER depletion in breast cancer cells through SMAD4-mediated ubiquitination.

  Breast cancer research and treatment 20121101

• Chemical composition of hexane extract of Citrus aurantifolia and anti-Mycobacterium tuberculosis activity of some of its constituents.

  Molecules (Basel, Switzerland) 20120919

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  World journal of gastroenterology 20120514

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  Zebrafish 20100301

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• Effects of storage conditions on furocoumarin levels in intact, chopped, or homogenized parsnips.

  Journal of agricultural and food chemistry 20020424

• Chalcones and other constituents of Dorstenia prorepens and Dorstenia zenkeri.

  Phytochemistry 20020401

• Amino acids in SRS1 and SRS6 are critical for furanocoumarin metabolism by CYP6B1v1, a cytochrome P450 monooxygenase.

  Insect molecular biology 20020401

• Analysis of limette and bergamot distilled essential oils by HPLC.

  Annali di chimica 20020401

• Simultaneous determination of furanocoumarins in infusions and decoctions from 'Carapiá' (dorstenia species) by high-performance liquid chromatography.

  Journal of agricultural and food chemistry 20020313

• Bullous phytophotodermatitis associated with high natural concentrations of furanocoumarins in limes.

  American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20020301

• Simple and rapid determination of psoralens in topic solutions using liquid chromatography.

  Journal of pharmaceutical and biomedical analysis 20020101

• Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.

  Clinical pharmacology and therapeutics 20020101

• Evaluation of synergism in the feeding deterrence of some furanocoumarins on Spodoptera littoralis.

  Journal of chemical ecology 20020101

• Oral administration of 5-methoxypsoralen affects the distribution and metabolism of 2-aminofluorene in Sprague-Dawley rats.

  In vivo (Athens, Greece) 20020101

• In vivo effect of 5- and 8-methoxypsoralens and cimetidine on R,S-warfarin metabolism in rat.

  Journal of applied toxicology : JAT 20020101

• Photosensitization and mutation induced in Escherichia coli and Saccharomyces cerevisiae strains by dorstenin, a psoralen analog isolated from Dorstenia bahiensis.

  Planta medica 20011201

• Anaphylaxis to 5-methoxypsoralen during photochemotherapy.

  The British journal of dermatology 20011101

• Indolopyridoquinazoline alkaloid from Leptothyrsa sprucei.

  Phytochemistry 20011001

• Inhibition of itch-scratch response by fruits of Cnidium monnieri in mice.

  Biological & pharmaceutical bulletin 20010901

• Plasma and skin concentration of 5-methoxypsoralen in psoriatic patients after oral administration.

  The Journal of investigative dermatology 20010801

• Chemical constituents of Prangos tschiniganica; structure elucidation and absolute configuration of coumarin and furanocoumarin derivatives with anti-HIV activity.

  Chemical & pharmaceutical bulletin 20010701

• Effects of silperisone on the excitation process in Ranvier nodes.

  General physiology and biophysics 20010601

• [Heracl'eum mantegazzi'anum: photosensitization].

  Praxis 20010118

• Seville orange juice-felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins.

  Clinical pharmacology and therapeutics 20010101

• The psoralens adversely affect reproductive function in male wistar rats.

  Reproductive toxicology (Elmsford, N.Y.) 20010101

• Furanocoumarins in celery and parsnips: method and multiyear Canadian survey.

  Journal of AOAC International 20010101

• Medicinal and ethnoveterinary remedies of hunters in Trinidad.

  BMC complementary and alternative medicine 20010101

• Inhibition of human CYP3A4 activity by grapefruit flavonoids, furanocoumarins and related compounds.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20010101

• Hepatitis from 5-methoxypsoralen occurring in a patient with previous flucloxacillin hepatitis.

  The Australasian journal of dermatology 19991101

• Topical or oral administration with an extract of Polypodium leucotomos prevents acute sunburn and psoralen-induced phototoxic reactions as well as depletion of Langerhans cells in human skin.

  Photodermatology, photoimmunology & photomedicine 19970101

• Antibacterial and antifungal polyine compounds from Glehnia littoralis ssp. leiocarpa.

  Planta medica 19960601

• Suksdorfin: an anti-HIV principle from Lomatium suksdorfii, its structure-activity correlation with related coumarins, and synergistic effects with anti-AIDS nucleosides.

  Bioorganic & medicinal chemistry 19941001