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Functionalized chromans and isochromans via a diastereoselective Pd(0)-catalyzed carboiodination.
Organic letters 20120921
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1'-Benzylspiro-[chromene-2,4'-piperi-dine]-4-carbonitrile.
Acta crystallographica. Section E, Structure reports online 20120901
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Synthesis and pharmacological activity of N-(2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-yl)-4H-1,2,4-benzothiadiazine-3-carboxamides 1,1-dioxides on rat uterus, rat aorta and rat pancreatic β-cells.
European journal of medicinal chemistry 20120801
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N-Aryl-N'-(chroman-4-yl)ureas and thioureas display in vitro anticancer activity and selectivity on apoptosis-resistant glioblastoma cells: screening, synthesis of simplified derivatives, and structure-activity relationship analysis.
European journal of medicinal chemistry 20120801
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3-O-Methyl-1-isomangostin.
Acta crystallographica. Section E, Structure reports online 20120601
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Ligand-specific roles for transmembrane 5 serine residues in the binding and efficacy of dopamine D(1) receptor catechol agonists.
Molecular pharmacology 20120501
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Gastroprotective effect of anti-cancer compound rohitukine: possible role of gastrin antagonism and H(+) K (+)-ATPase inhibition.
Naunyn-Schmiedeberg's archives of pharmacology 20120301
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Fusarium proliferatum, an endophytic fungus from Dysoxylum binectariferum Hook.f, produces rohitukine, a chromane alkaloid possessing anti-cancer activity.
Antonie van Leeuwenhoek 20120201
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Synthesis of chromans via Pd-catalyzed alkene carboetherification reactions.
Chemical communications (Cambridge, England) 20120114
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Synthesis and DPPH radical scavenging activity of prenylated phenol derivatives.
Molecules (Basel, Switzerland) 20120106
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Design, synthesis and in vitro evaluation of novel chroman-4-one, chroman, and 2H-chromene derivatives as human rhinovirus capsid-binding inhibitors.
Bioorganic & medicinal chemistry 20111215
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Genome-wide association study identifies common variants associated with circulating vitamin E levels.
Human molecular genetics 20111001
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Isoxazole substituted chromans against oxidative stress-induced neuronal damage.
Bioorganic & medicinal chemistry 20110815
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6-Hy-droxy-2,5,7,8-tetra-methyl-3,4-dihydro-2H-1-benzopyran-2-carbonitrile, from synchrotron data.
Acta crystallographica. Section E, Structure reports online 20110801
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Toxic metabolite formation from Troglitazone (TGZ): new insights from a DFT study.
Chemical research in toxicology 20110718
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α-Tocopheryl phosphate: uptake, hydrolysis, and antioxidant action in cultured cells and mouse.
Free radical biology & medicine 20110615
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Mapping the catechol binding site in dopamine D₁ receptors: synthesis and evaluation of two parallel series of bicyclic dopamine analogues.
ChemMedChem 20110606
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Tocotrienol combination therapy results in synergistic anticancer response.
Frontiers in bioscience (Landmark edition) 20110601
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Anti-invasive activity of α-tocopherol against hepatoma cells in culture via protein kinase C inhibition.
Journal of clinical biochemistry and nutrition 20110501
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Metabolic manipulators: a well founded strategy to combat mitochondrial dysfunction.
Journal of inherited metabolic disease 20110401
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Chroman and tetrahydroquinoline ureas as potent TRPV1 antagonists.
Bioorganic & medicinal chemistry letters 20110301
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3-Benzyl-5,7-dimeth-oxy-chroman-4-ol.
Acta crystallographica. Section E, Structure reports online 20110301
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2,2,5,7,8-Penta-methyl-chroman-6-yl 2,3,4,6-tetra-O-acetyl-α-d-glucopyran-oside from synchrotron data.
Acta crystallographica. Section E, Structure reports online 20110301
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Development of chromanes as novel inhibitors of the uncoupling proteins.
Chemistry & biology 20110225
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Culturability and secondary metabolite diversity of extreme microbes: expanding contribution of deep sea and deep-sea vent microbes to natural product discovery.
Marine biotechnology (New York, N.Y.) 20110201
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rac-6-Hy-droxy-2,5,7,8-tetra-methyl-chroman-2-carboxamide from synchrotron data.
Acta crystallographica. Section E, Structure reports online 20110201
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Two new chroman derivations from the endophytic Penicillium sp. DCS523.
Molecules (Basel, Switzerland) 20110118
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Imidazolylchromanone oxime ethers as potential anticonvulsant agents: Anticonvulsive evaluation in PTZ-kindling model of epilepsy and SAR study.
Bioorganic & medicinal chemistry letters 20110115
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α-Tocopheryloxyacetic acid: a novel chemotherapeutic that stimulates the antitumor immune response.
Breast cancer research : BCR 20110101
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Lycopene inhibits NF-kB-mediated IL-8 expression and changes redox and PPARγ signalling in cigarette smoke-stimulated macrophages.
PloS one 20110101
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Antioxidants and the integrity of ocular tissues.
Veterinary medicine international 20110101
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Mutagenic Tests Confirm That New Acetylacetonate Pt(II) Complexes Induce Apoptosis in Cancer Cells Interacting with Nongenomic Biological Targets.
Metal-based drugs 20110101
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The vitamin E analog, alpha-tocopheryloxyacetic acid enhances the anti-tumor activity of trastuzumab against HER2/neu-expressing breast cancer.
BMC cancer 20110101
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Phytoestrogens in postmenopausal indications: A theoretical perspective.
Pharmacognosy reviews 20110101
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Synthesis of functionalized chromans by PnBu3-catalyzed reactions of salicylaldimines and salicylaldehydes with allenic ester.
Organic letters 20101217
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6-Chloro-4-(2-phenyl-ethen-yl)chroman-2-one.
Acta crystallographica. Section E, Structure reports online 20101201
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Chemistry and biochemistry of dietary polyphenols.
Nutrients 20101201
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Hybrid-increased radical-scavenging activity of resveratrol derivatives by incorporating a chroman moiety of vitamin E.
Chemistry (Weinheim an der Bergstrasse, Germany) 20101115
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New troglitazone derivatives devoid of PPARγ agonist activity display an increased antiproliferative effect in both hormone-dependent and hormone-independent breast cancer cell lines.
Breast cancer research and treatment 20101101
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Organocatalytic asymmetric tandem Michael addition-hemiacetalization: a route to chiral dihydrocoumarins, chromanes, and 4H-chromenes.
The Journal of organic chemistry 20101015
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Protective Effects of Vitamin E Analogs against Carbon Tetrachloride-Induced Fatty Liver in Rats.
Journal of clinical biochemistry and nutrition 20100901
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Structure-activity relationship of indoline-2-carboxylic acid N-(substituted)phenylamide derivatives.
Bioorganic & medicinal chemistry letters 20100801
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Tetracyclic chromane derivatives from Rhododendron anthopogonoides.
Journal of natural products 20100723
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Bioglycans and natural glycosides as a promising research topic in bioorganic chemistriy.
Acta naturae 20100701
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alpha-Tocopherol enhances degranulation in RBL-2H3 mast cells.
Molecular nutrition & food research 20100501
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Dysoxylum binectariferum Hook.f (Meliaceae), a rich source of rohitukine.
Fitoterapia 20100301
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Enantioselective total synthesis of the natural gamma-tocopherol metabolite (S)-gamma-CEHC [(S)-LLU-alpha].
Organic letters 20100205
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Modulation of the mitochondrial cytochrome bc1 complex activity by chromanols and related compounds.
Chemical research in toxicology 20100101
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Troglitazone.
Handbook of experimental pharmacology 20100101
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Reduced levels of hydroxylated, polyunsaturated ultra long-chain fatty acids in the serum of colorectal cancer patients: implications for early screening and detection.
BMC medicine 20100101
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Enhanced antiproliferative and apoptotic response to combined treatment of gamma-tocotrienol with erlotinib or gefitinib in mammary tumor cells.
BMC cancer 20100101
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Downregulation of Epidermal Growth Factor Receptor Expression Contributes to alpha-TEA's Proapoptotic Effects in Human Ovarian Cancer Cell Lines.
Journal of oncology 20100101
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New benzofuran derivatives as an antioxidant agent.
Indian journal of pharmaceutical sciences 20100101
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Brain mitochondrial dysfunction in aging, neurodegeneration, and Parkinson's disease.
Frontiers in aging neuroscience 20100101
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Recent biomimetic and organocatalytic syntheses of alpha-tocopherol.
Chimia 20100101
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Tocotrienols inhibit lipopolysaccharide-induced pro-inflammatory cytokines in macrophages of female mice.
Lipids in health and disease 20100101
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Cytotoxic terpene quinones from marine sponges.
Marine drugs 20100101
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The hunt for natural skin whitening agents.
International journal of molecular sciences 20091201
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Stereocontrolled generation of the (2R) chroman core of vitamin E: total synthesis of (2R,4'RS,8'RS)-alpha-tocopherol.
Organic letters 20091105
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Resolution and absolute configuration assignment of a natural racemic chromane from Peperomia obtusifolia (Piperaceae).
Chirality 20091001
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9-Meth-oxy-6a,11a-dimethyl-6a,11a-dihydro-6H-1-benzofuro[3,2-c]chromen-3-ol from Dalbergia oliveri.
Acta crystallographica. Section E, Structure reports online 20091001
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Design and synthesis of novel neuroprotective 1,2-dithiolane/chroman hybrids.
Bioorganic & medicinal chemistry 20090901
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Chromane derivatives of small aromatic molecules: Chemoenzymatic synthesis and growth inhibitory activity on human tumor cell line LoVo WT.
Bioorganic & medicinal chemistry 20090815
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N'-tert-Butyl-N'-(3,5-dimethyl-benzo-yl)-2,2-dimethyl-4-oxochroman-6-carbo-hydrazide.
Acta crystallographica. Section E, Structure reports online 20090801
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Synthesis and antirhinovirus activity of new 3-benzyl chromene and chroman derivatives.
Bioorganic & medicinal chemistry 20090515
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Configuration of the vitamin E analogue garcinoic acid extracted from Garcinia Kola seeds.
Chirality 20090501
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PPh3-catalyzed domino reaction: a facile method for the synthesis of chroman derivatives.
Organic letters 20090219
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Synthesis and analysis of resorcinol-acetone copolymer.
Molecules (Basel, Switzerland) 20090113
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A cardiologic approach to non-insulin antidiabetic pharmacotherapy in patients with heart disease.
Cardiovascular diabetology 20090101
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Rho kinase (ROCK) inhibitors and their application to inflammatory disorders.
Current topics in medicinal chemistry 20090101
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[Cytotoxicity of troglitazone, structural analogue of alpha-tocopherol is mediated by inhibition of NAD(P)H:quinone oxidoreductase].
Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20090101
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Structural, chemical and biological aspects of antioxidants for strategies against metal and metalloid exposure.
Oxidative medicine and cellular longevity 20090101
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Advances toward new antidepressants with dual serotonin transporter and 5-HT1A receptor affinity within a class of 3-aminochroman derivatives. Part 2.
Journal of medicinal chemistry 20081113
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Reduction of pyrrolyl- and indolylamides with BH3 x THF: cyclodeoxygenation versus deoxygenation.
The Journal of organic chemistry 20081107
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Emerging role for antioxidant therapy in protection against diabetic cardiac complications: experimental and clinical evidence for utilization of classic and new antioxidants.
Current cardiology reviews 20081101
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3-Benzyl-idene-6-methoxy-chroman-4-one.
Acta crystallographica. Section E, Structure reports online 20081101
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Electrochemical oxidation of troglitazone: identification and characterization of the major reactive metabolite in liver microsomes.
Chemical research in toxicology 20081001
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Synthesis of 1-oxadecalins from anisole promoted by tungsten.
Journal of the American Chemical Society 20080917
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Ruthenium-catalyzed enantioselective carbon-carbon bond forming reaction via allenylidene-ene process: synthetic approach to chiral heterocycles such as chromane, thiochromane, and 1,2,3,4-tetrahydroquinoline derivatives.
Journal of the American Chemical Society 20080813
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Synthesis and activity on rat aorta rings and rat pancreatic beta-cells of ring-opened analogues of benzopyran-type potassium channel activators.
Bioorganic & medicinal chemistry 20080601
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Petiolins A-C, phloroglucinol derivatives from Hypericum pseudopetiolatum var. kiusianum.
Bioorganic & medicinal chemistry 20080515
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Design, synthesis, and antioxidant potency of novel alpha-tocopherol analogues in isolated membranes and intact cells.
Free radical biology & medicine 20080401
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Assignment of the 1H and 13C NMR of tocotrienols.
Magnetic resonance in chemistry : MRC 20080301
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Synthesis of chroman-2-carboxylic acid N-(substituted)phenylamides and their inhibitory effect on nuclear factor-kappaB (NF-kappaB) activation.
Archives of pharmacal research 20080201
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New chromane derivatives isolated from the brown alga, Sargassum micracanthum.
Chemical & pharmaceutical bulletin 20080101
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Gold-catalyzed synthesis of chroman, dihydrobenzofuran, dihydroindole, and tetrahydroquinoline derivatives.
Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
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Stereoselective synthesis of 4-dehydroxydiversonol employing enantioselective palladium-catalysed domino reactions.
Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
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6,6'-oxydichroman.
Acta crystallographica. Section E, Structure reports online 20080101
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Highly selective metal mediated ortho-alkylation of phenol. First platinum containing organometallic chromane analogues.
Dalton transactions (Cambridge, England : 2003) 20071228
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Retro-Diels-Alder reaction of 4H-1,2-benzoxazines to generate o-quinone methides: involvement of highly polarized transition states.
The Journal of organic chemistry 20071221
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One-pot regioselective synthesis of chromanyl(phenyl)-lambda(3)-iodanes: tandem oxidative cyclization and lambda(3)-iodanation of 3-phenylpropanols.
Organic letters 20070510
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Synthesis and insecticidal activity of chromanone and chromone analogues of diacylhydrazines.
Bioorganic & medicinal chemistry 20070301
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Identification of a nonpeptidic and conformationally restricted bradykinin B1 receptor antagonist with anti-inflammatory activity.
Journal of medicinal chemistry 20070222
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Synthesis of vitamin E.
Vitamins and hormones 20070101
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[Membranotropic and pro-oxidative effects of alpha-tocopherol short-chain derivatives].
Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20070101
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Enantioselective palladium-catalyzed total synthesis of vitamin e by employing a domino Wacker-Heck reaction.
Chemistry (Weinheim an der Bergstrasse, Germany) 20061124
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Total synthesis of (S)-equol.
Organic letters 20061123
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Metabolic and non-metabolic factors determining troglitazone hepatotoxicity: a review.
Drug metabolism and pharmacokinetics 20061001
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The novel antidyskinetic drug sarizotan elicits different functional responses at human D2-like dopamine receptors.
Neuropharmacology 20060901
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Ag(I)-catalyzed sequential C-C and C-O bond formations between phenols and dienes with atom economy.
The Journal of organic chemistry 20060818
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Inhibitory effect of chroman carboxamide on interleukin-6 expression in response to lipopolysaccharide by preventing nuclear factor-kappaB activation in macrophages.
European journal of pharmacology 20060814
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Discovery of thiochroman and chroman derivatives as pure antiestrogens and their structure-activity relationship.
Bioorganic & medicinal chemistry 20060715
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Comparative antioxidant activity of tocotrienols and the novel chromanyl-polyisoprenyl molecule FeAox-6 in isolated membranes and intact cells.
Molecular and cellular biochemistry 20060701
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Synthesis and biological evaluation of novel, peripherally selective chromanyl imidazolethione-based inhibitors of dopamine beta-hydroxylase.
Journal of medicinal chemistry 20060209
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Antioxidant effect of FeAOX-6 on free radical species produced during iron catalyzed breakdown of tert-butyl hydroperoxide.
Free radical research 20060201
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Comparative effects of RRR-alpha- and RRR-gamma-tocopherol on proliferation and apoptosis in human colon cancer cell lines.
BMC cancer 20060101
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Potent and highly selective kappa opioid receptor agonists incorporating chroman- and 2,3-dihydrobenzofuran-based constraints.
Bioorganic & medicinal chemistry letters 20051201
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Stable isotope characterization of the ortho-oxygenated phenylpropanoids: coumarin and melilotol.
Journal of agricultural and food chemistry 20051130
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Automated screening with confirmation of mechanism-based inactivation of CYP3A4, CYP2C9, CYP2C19, CYP2D6, and CYP1A2 in pooled human liver microsomes.
Drug metabolism and disposition: the biological fate of chemicals 20050801
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Design and synthesis of novel diphenacoum-derived, conformation-restricted vitamin K 2,3-epoxide reductase inhibitors.
Bioorganic & medicinal chemistry letters 20050516
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Importance of chroman ring and tyrosine phosphorylation in the subtype-specific translocation and activation of diacylglycerol kinase alpha by D-alpha-tocopherol.
Genes to cells : devoted to molecular & cellular mechanisms 20050401
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Resolution of (S,S)-4-(2,2,4-trimethylchroman-4-yl)phenyl camphanate and its 4-chromanyl epimer by crystallization.
Acta crystallographica. Section C, Crystal structure communications 20050101
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[Effect of alpha-tocopherol and its derivatives on actinomycin D induced apoptosis of rat thymocytes].
Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20050101
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Inhibitory mechanism of chroman compound on LPS-induced nitric oxide production and nuclear factor-kappaB activation.
Biochemical and biophysical research communications 20041203
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In vitro neuroprotection by novel antioxidants in guinea-pig urinary bladder subjected to anoxia-glucopenia/reperfusion damage.
Naunyn-Schmiedeberg's archives of pharmacology 20041201
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Biomimetic enantioselective total synthesis of (-)-siccanin via the Pd-catalyzed asymmetric allylic alkylation (AAA) and sequential radical cyclizations.
Journal of the American Chemical Society 20041006
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Electron-induced (EI) mass fragmentation is directed by intra-molecular H-bonding in two isomeric benzodipyran systems.
Molecules (Basel, Switzerland) 20040930
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Synthesis of chroman analogues of lipoic acid and evaluation of their activity against reperfusion arrhythmias.
Bioorganic & medicinal chemistry 20040915
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A new artificial cyclase for polyprenoids: enantioselective total synthesis of (-)-chromazonarol, (+)-8-epi-puupehedione, and (-)-11'-deoxytaondiol methyl ether.
Journal of the American Chemical Society 20040915
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Preventive effects of a water-soluble derivative of chroman moiety of vitamin E on lipid hydroperoxide-induced cell injuries and DNA cleavages through repressions of oxidative stress in the cytoplasm of human keratinocytes.
Journal of cellular biochemistry 20040601
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Incorporation of an oxygen from water into troglitazone quinone by cytochrome P450 and myeloperoxidase.
Drug metabolism and disposition: the biological fate of chemicals 20040401
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Intramolecular arylation reactions of alkenes: a flexible approach to chromans and tetrahydroquinoline derivatives.
Journal of the American Chemical Society 20040324
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A planar catechin analogue having a more negative oxidation potential than (+)-catechin as an electron transfer antioxidant against a peroxyl radical.
Chemical research in toxicology 20040101
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New perspectives on vitamin E: gamma-tocopherol and carboxyelthylhydroxychroman metabolites in biology and medicine.
Free radical biology & medicine 20040101
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Biological functions and metabolic fate of vitamin E revisited.
Journal of biomedical science 20040101
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Soft ionization mass spectrometry of chromanols produces radical cation molecular ions.
European journal of mass spectrometry (Chichester, England) 20040101
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Comprehensive study on vitamin C equivalent antioxidant capacity (VCEAC) of various polyphenolics in scavenging a free radical and its structural relationship.
Critical reviews in food science and nutrition 20040101
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Total synthesis of the highly potent anti-HIV natural product daurichromenic acid along with its two chromane derivatives, rhododaurichromanic acids A and B.
Organic letters 20031113
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Physicochemical and crystal structure analyses of the antidiabetic agent troglitazone.
Chemical & pharmaceutical bulletin 20030701
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A cytotoxic butenolide, two new dolabellane diterpenoids, a chroman and a benzoquinol derivative formosan Casearia membranacea.
Planta medica 20030701
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Vitamin E analogues as inducers of apoptosis: structure-function relation.
British journal of cancer 20030616
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Stereochemical and mechanistic aspects of dioxygenase-catalysed benzylic hydroxylation of indene and chromane substrates.
Organic & biomolecular chemistry 20030421
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Troglitazone-induced intracellular oxidative stress in rat hepatoma cells: a flow cytometric assessment.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20030301
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A planar catechin analogue as a promising antioxidant with reduced prooxidant activity.
Chemical research in toxicology 20030101
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[Antioxidant properties of a leaf extract from Aronia (Aronia melanocarba) containing proanthocyanidins].
Biomeditsinskaia khimiia 20030101
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Design, synthesis, and antioxidant activity of FeAOX-6, a novel agent deriving from a molecular combination of the chromanyl and polyisoprenyl moieties.
Free radical biology & medicine 20021215
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Chiroptical properties of 2,3-dihydrobenzo[b]furan and chromane chromophores in naturally occurring O-heterocycles.
Chirality 20010801
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Enzyme-induction dependent bioactivation of troglitazone and troglitazone quinone in vivo.
Chemical research in toxicology 20010801
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New chroman derivatives from the Japanese liverworts Metacalypogeia cordifolia and Cephalozia otaruensis.
Chemical & pharmaceutical bulletin 20010701
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Serotonin receptor and transporter ligands - current status.
Current medicinal chemistry 20010701
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Lewis acid-promoted deoxygenative di[beta,beta-bis(ethylthio)]vinylation of aldehydes with trimethylsilylketene bis(ethylthio)acetal.
The Journal of organic chemistry 20010601
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Oxidative catabolism of alpha-tocopherol in rat liver microsomes.
Lipids 20010401
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Studies on the metabolism of troglitazone to reactive intermediates in vitro and in vivo. Evidence for novel biotransformation pathways involving quinone methide formation and thiazolidinedione ring scission.
Chemical research in toxicology 20010101
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[Effect of vitamin E and its functional analogs with different molecular structures on growth and lipids content of Pythium debaryanum].
Mikrobiologiia 20010101
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Liquid chromatography-mass spectrometry analysis of propolis.
Phytochemical analysis : PCA 20010101
