500-66-3 | Olivetol

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$31.00	$22.00
5g	95%	in stock	$70.00	$49.00
25g	95%	in stock	$175.00	$122.00
100g	95%	in stock	$598.00	$418.00

Description

• Catalog Number: AB46807
• Chemical Name: Olivetol
• CAS Number: 500-66-3
• Molecular Formula: C11H16O2
• Molecular Weight: 180.2435
• MDL Number: MFCD00002293
• SMILES: CCCCCc1cc(O)cc(c1)O

Computed Properties

• Complexity: 126
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4
• XLogP3: 3.6

Literature

• Characterization of the structural determinants required for potent mechanism-based inhibition of human cytochrome P450 1A1 by cannabidiol.

  Chemico-biological interactions 20140525

• Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6.

  Drug metabolism and disposition: the biological fate of chemicals 20111101

• Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: role of phenolic hydroxyl groups in the resorcinol moiety.

  Life sciences 20110411

• Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum.

  Genome biology 20110101

• Phase I hydroxylated metabolites of the K2 synthetic cannabinoid JWH-018 retain in vitro and in vivo cannabinoid 1 receptor affinity and activity.

  PloS one 20110101

• Antioxidant, antimicrobial and antiproliferative activities of five lichen species.

  International journal of molecular sciences 20110101

• Systematic review of herbals as potential anti-inflammatory agents: Recent advances, current clinical status and future perspectives.

  Pharmacognosy reviews 20110101

• Functional characterization of the promiscuous prenyltransferase responsible for furaquinocin biosynthesis: identification of a physiological polyketide substrate and its prenylated reaction products.

  The Journal of biological chemistry 20101217

• Alkylresorcinol synthases expressed in Sorghum bicolor root hairs play an essential role in the biosynthesis of the allelopathic benzoquinone sorgoleone.

  The Plant cell 20100301

• In silicio expression analysis of PKS genes isolated from Cannabis sativa L.

  Genetics and molecular biology 20100101

• Identification of candidate genes affecting Delta9-tetrahydrocannabinol biosynthesis in Cannabis sativa.

  Journal of experimental botany 20090901

• Characterization of olivetol synthase, a polyketide synthase putatively involved in cannabinoid biosynthetic pathway.

  FEBS letters 20090618

• HTRF: A technology tailored for drug discovery - a review of theoretical aspects and recent applications.

  Current chemical genomics 20090101

• Chemoenzymatic syntheses of prenylated aromatic small molecules using Streptomyces prenyltransferases with relaxed substrate specificities.

  Bioorganic & medicinal chemistry 20080901

• Antibacterial cannabinoids from Cannabis sativa: a structure-activity study.

  Journal of natural products 20080801

• Activities of 2,4-dihydroxy-6-n-pentylbenzoic acid derivatives.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101

• Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors.

  Bioorganic & medicinal chemistry 20070815

• Biosynthesis of lipid resorcinols and benzoquinones in isolated secretory plant root hairs.

  Journal of experimental botany 20070101

• In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands.

  British journal of pharmacology 20061001

• Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products.

  Nature 20050616

• Cloning and over-expression of a cDNA encoding a polyketide synthase from Cannabis sativa.

  Plant physiology and biochemistry : PPB 20040401

• Prenylation of olivetolate by a hemp transferase yields cannabigerolic acid, the precursor of tetrahydrocannabinol.

  FEBS letters 19980508