504433-23-2 | GW441756

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$20.00	$14.00
10mg	98%	in stock	$55.00	$38.00
50mg	98%	in stock	$149.00	$104.00

Description

• Catalog Number: AD25398
• Chemical Name: GW441756
• CAS Number: 504433-23-2
• Molecular Formula: C17H13N3O
• Molecular Weight: 275.30461999999994
• MDL Number: MFCD17010281
• SMILES: O=C1Nc2c(C1=Cc1cn(c3c1cccc3)C)nccc2

Computed Properties

• Complexity: 461
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 21
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1.9

Literature

• Quercetin reverses experimental pulmonary arterial hypertension by modulating the TrkA pathway.

  Experimental cell research 20151115

• Identification of 4-aminopyrazolylpyrimidines as potent inhibitors of Trk kinases.

  Journal of medicinal chemistry 20080814

• Discovery and in vitro evaluation of potent TrkA kinase inhibitors: oxindole and aza-oxindoles.

  Bioorganic & medicinal chemistry letters 20040223