510-30-5 | Echinocystic acid

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$25.00	$18.00
50mg	95%	in stock	$188.00	$132.00
100mg	95%	in stock	$327.00	$229.00

Description

• Catalog Number: AG20963
• Chemical Name: Echinocystic acid
• CAS Number: 510-30-5
• Molecular Formula: C30H48O4
• Molecular Weight: 472.6997
• MDL Number: MFCD00017295
• SMILES: O[C@@H]1C[C@]2(C)C(=CC[C@H]3[C@@]2(C)CCC2[C@]3(C)CC[C@@H](C2(C)C)O)[C@@H]2[C@@]1(CCC(C2)(C)C)C(=O)O

Computed Properties

• Complexity: 919
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 9
• Heavy Atom Count: 34
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 1
• XLogP3: 6.9

Literature

• Synthesis and anti-HCV entry activity studies of β-cyclodextrin-pentacyclic triterpene conjugates.

  ChemMedChem 20140501

• Development of oleanane-type triterpenes as a new class of HCV entry inhibitors.

  Journal of medicinal chemistry 20130613

• Echinocystic acid ameliorates lung inflammation in mice and alveolar macrophages by inhibiting the binding of LPS to TLR4 in NF-κB and MAPK pathways.

  Biochemical pharmacology 20120801

• Echinocystic acid 3,16-O-bisglycosides from Albizia procera.

  Phytochemistry 20100801

• Murine metabolism and absorption of lancemaside A, an active compound in the roots of Codonopsis lanceolata.

  Journal of natural medicines 20100701

• A sensitive liquid chromatography-electrospray tandem mass spectrometric method for lancemaside A and its metabolites in plasma and a pharmacokinetic study in mice.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100701

• Triterpene glycosides from Agrostemma gracilis.

  Phytochemistry 20100401

• Protective effects of echinocystic acid isolated from Gleditsia sinensis Lam. against acute myocardial ischemia.

  Fitoterapia 20100101

• The interleukin-18 inhibitory activities of echinocystic acid and its saponins from Impatiens pritzellii var. hupehensis.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20090101

• Immunomodulatory effects of two sapogenins 1 and 2 isolated from Luffa cylindrica in Balb/C mice.

  Bioorganic & medicinal chemistry letters 20070315

• Beta-D-xylopyranosyl-(1-->3)-beta-D-glucuronopyranosyl echinocystic acid isolated from the roots of Codonopsis lanceolata induces caspase-dependent apoptosis in human acute promyelocytic leukemia HL-60 cells.

  Biological & pharmaceutical bulletin 20050501

• Molecular mechanisms of echinocystic acid-induced apoptosis in HepG2 cells.

  Biochemical and biophysical research communications 20040827

• Echinocystic acid induces apoptosis in HL-60 cells through mitochondria-mediated death pathway.

  Cancer letters 20040820

• A review of natural and modified betulinic, ursolic and echinocystic acid derivatives as potential antitumor and anti-HIV agents.

  Mini reviews in medicinal chemistry 20030901

• Bioactive saponins from Acacia tenuifolia from the suriname rainforest.

  Journal of natural products 20020201

• Anti-AIDS agents, 21. Triterpenoid saponins as anti-HIV principles from fruits of Gleditsia japonica and Gymnocladus chinensis, and a structure-activity correlation.

  Journal of natural products 19950901