5122-94-1 | 4-Biphenylboronic acid

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$8.00	$5.00
10g	98%	in stock	$10.00	$7.00
25g	98%	in stock	$18.00	$12.00
100g	98%	in stock	$66.00	$46.00

Description

• Catalog Number: AB49295
• Chemical Name: 4-Biphenylboronic acid
• CAS Number: 5122-94-1
• Molecular Formula: C12H11BO2
• Molecular Weight: 198.0255
• MDL Number: MFCD00093311
• SMILES: OB(c1ccc(cc1)c1ccccc1)O

Computed Properties

• Complexity: 182
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2

Upstream Synthesis Route

(1,1'-Biphenyl-4-yl)boronic acid is a versatile compound frequently used in chemical synthesis due to its ability to participate in various reactions, particularly in the field of organic chemistry. This boronic acid derivative serves as a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and materials science.In chemical synthesis, (1,1'-Biphenyl-4-yl)boronic acid acts as a crucial reagent in Suzuki-Miyaura cross-coupling reactions, which enable the formation of carbon-carbon bonds under mild conditions. This reaction is widely utilized in the construction of complex organic molecules, making it an essential tool for medicinal chemists and synthetic organic chemists alike.Furthermore, (1,1'-Biphenyl-4-yl)boronic acid can also participate in palladium-catalyzed coupling reactions, allowing for the introduction of the biphenyl moiety into various organic frameworks. This functional group can be further elaborated through various transformations, expanding its utility in synthetic chemistry.Overall, the application of (1,1'-Biphenyl-4-yl)boronic acid in chemical synthesis provides chemists with a powerful tool for the construction of diverse molecular structures, enabling the efficient and selective formation of carbon-carbon bonds in complex organic molecules.

Literature

• 2-Bromo-p-terphen-yl.

  Acta crystallographica. Section E, Structure reports online 20100401

• Synthesis and evaluation of 3-(dihydroxyboryl)benzoic acids as D,D-carboxypeptidase R39 inhibitors.

  Journal of medicinal chemistry 20091008

• Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase.

  Journal of medicinal chemistry 20081127

• Enhancing effect of phenylboronic acid compounds and their interactions with the diol groups of saccharides in a capillary electrophoresis-chemiluminescence detection system.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20070201