5271-26-1 | 2-phenylpiperazine

Packsize	Purity	Availability	Price	Discounted Price
1g	96%	in stock	$30.00	$21.00
5g	96%	in stock	$117.00	$82.00
25g	96%	in stock	$371.00	$260.00

Description

• Catalog Number: AB62942
• Chemical Name: 2-phenylpiperazine
• CAS Number: 5271-26-1
• Molecular Formula: C10H14N2
• Molecular Weight: 162.2316
• MDL Number: MFCD01871362
• SMILES: N1CCNC(C1)c1ccccc1
• NSC Number: 70392

Computed Properties

• Complexity: 130
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• Undefined Atom Stereocenter Count: 1
• XLogP3: 0.7

Literature

• Development and characterization of endocannabinoid hydrolases FAAH and MAGL inhibitors bearing a benzotriazol-1-yl carboxamide scaffold.

  Bioorganic & medicinal chemistry 20121101

• Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for α₁-adrenoceptor subtypes.

  European journal of medicinal chemistry 20110701

• Synthesis and Biological Evaluation of New 3-Phenyl-1-[(4-arylpiperazin-1-yl)alkyl]-piperidine-2,6-diones.

  Scientia pharmaceutica 20110101

• Design, synthesis and pharmacological evaluation of new 1-[3-(4-arylpiperazin-1-yl)-2-hydroxy-propyl]-3,3-diphenylpyrrolidin-2-one derivatives with antiarrhythmic, antihypertensive, and alpha-adrenolytic activity.

  European journal of medicinal chemistry 20091001

• Discovery process and pharmacological characterization of 2-(S)-(4-fluoro-2-methylphenyl)piperazine-1-carboxylic acid [1-(R)-(3,5-bis-trifluoromethylphenyl)ethyl]methylamide (vestipitant) as a potent, selective, and orally active NK1 receptor antagonist.

  Journal of medicinal chemistry 20090528

• Aminocyclohexylsulfonamides: discovery of metabolically stable alpha(1a/1d)-selective adrenergic receptor antagonists for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS).

  Bioorganic & medicinal chemistry letters 20071115