53-84-9 | NAD+

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$6.00	$4.00
1g	98%	in stock	$11.00	$8.00
5g	98%	in stock	$27.00	$19.00
10g	≥98%	in stock	$43.00	$30.00
25g	98%	in stock	$78.00	$55.00

Description

• Catalog Number: AB45622
• Chemical Name: NAD+
• CAS Number: 53-84-9
• Molecular Formula: C21H27N7O14P2
• Molecular Weight: 663.4251
• MDL Number: MFCD00150381
• SMILES: OC1C(COP(=O)(OP(=O)(OCC2OC(C(C2O)O)n2cnc3c2ncnc3N)O)[O-])OC(C1O)[n+]1cccc(c1)C(=O)N
• NSC Number: 757121

Computed Properties

• Complexity: 1120
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 8
• Heavy Atom Count: 44
• Hydrogen Bond Acceptor Count: 18
• Hydrogen Bond Donor Count: 7
• Rotatable Bond Count: 11
• XLogP3: -6

Literature

• Impaired PARP activity in response to the β-adrenergic receptor agonist isoproterenol.

  Toxicology in vitro : an international journal published in association with BIBRA 20180801

• Oxyresveratrol stimulates mucin production in an NAD(+)-dependent manner in human intestinal goblet cells.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180801

• Inhibition of nicotinamide phosphoribosyltransferase and depletion of nicotinamide adenine dinucleotide contribute to arsenic trioxide suppression of oral squamous cell carcinoma.

  Toxicology and applied pharmacology 20170915

• Diacetyl/l-Xylulose Reductase Mediates Chemical Redox Cycling in Lung Epithelial Cells.

  Chemical research in toxicology 20170717

• Diquat-induced cellular pyridine nucleotide redox changes and alteration of metabolic enzyme activities in colonic carcinoma cells.

  Chemico-biological interactions 20170225

• Overexpression of the human DEK oncogene reprograms cellular metabolism and promotes glycolysis.

  PloS one 20170101

• Analyzing structure-function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells.

  Nucleic acids research 20161201

• NAD(P)H-dependent quinone oxidoreductase 1 (NQO1) and cytochrome P450 oxidoreductase (CYP450OR) differentially regulate menadione-mediated alterations in redox status, survival and metabolism in pancreatic β-cells.

  Toxicology letters 20161116

• Nephron-Specific Deletion of Circadian Clock Gene Bmal1 Alters the Plasma and Renal Metabolome and Impairs Drug Disposition.

  Journal of the American Society of Nephrology : JASN 20161001

• Poly(ADP-ribose) Polymerase 1 Represses Liver X Receptor-mediated ABCA1 Expression and Cholesterol Efflux in Macrophages.

  The Journal of biological chemistry 20160520

• Nickel-pincer cofactor biosynthesis involves LarB-catalyzed pyridinium carboxylation and LarE-dependent sacrificial sulfur insertion.

  Proceedings of the National Academy of Sciences of the United States of America 20160517

• Tyrosine phosphorylation of dihydrolipoamide dehydrogenase as a potential cadmium target and its inhibitory role in regulating mouse sperm motility.

  Toxicology 20160516

• Metabolism of isoniazid by neutrophil myeloperoxidase leads to isoniazid-NAD(+) adduct formation: A comparison of the reactivity of isoniazid with its known human metabolites.

  Biochemical pharmacology 20160415

• Oxaloacetate enhances neuronal cell bioenergetic fluxes and infrastructure.

  Journal of neurochemistry 20160401

• Effects of Ziram on Rat and Human 11β-Hydroxysteroid Dehydrogenase Isoforms.

  Chemical research in toxicology 20160321

• A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model.

  Journal of inherited metabolic disease 20160101

• Bioactivation of luteolin by tyrosinase selectively inhibits glutathione S-transferase.

  Chemico-biological interactions 20151005

• A biosynthetic pathway for a prominent class of microbiota-derived bile acids.

  Nature chemical biology 20150901

• Broadened Substrate Specificity of 3-Hydroxyethyl Bacteriochlorophyllide a Dehydrogenase (BchC) Indicates a New Route for the Biosynthesis of Bacteriochlorophyll a.

  The Journal of biological chemistry 20150807

• Entner-Doudoroff pathway for sulfoquinovose degradation in Pseudomonas putida SQ1.

  Proceedings of the National Academy of Sciences of the United States of America 20150804

• Ruthenium complexes as inhibitors of the aldo-keto reductases AKR1C1-1C3.

  Chemico-biological interactions 20150605

• Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1.

  Chemico-biological interactions 20150605

• Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure-activity relationships.

  Chemico-biological interactions 20150605

• Pharmacologic targeting of sirtuin and PPAR signaling improves longevity and mitochondrial physiology in respiratory chain complex I mutant Caenorhabditis elegans.

  Mitochondrion 20150501

• Organophosphate pesticides-induced changes in the redox status of rat tissues and protective effects of antioxidant vitamins.

  Environmental toxicology 20150401

• Methylmercury impairs canonical dopamine metabolism in rat undifferentiated pheochromocytoma (PC12) cells by indirect inhibition of aldehyde dehydrogenase.

  Toxicological sciences : an official journal of the Society of Toxicology 20150401

• Retinal toxicity, in vivo and in vitro, associated with inhibition of nicotinamide phosphoribosyltransferase.

  Toxicological sciences : an official journal of the Society of Toxicology 20150301

• Metabolic function for human renalase: oxidation of isomeric forms of β-NAD(P)H that are inhibitory to primary metabolism.

  Biochemistry 20150127

• High level of oxygen treatment causes cardiotoxicity with arrhythmias and redox modulation.

  Toxicology and applied pharmacology 20150101

• A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome.

  Cell metabolism 20141104

• Reduction of sulfamethoxazole hydroxylamine (SMX-HA) by the mitochondrial amidoxime reducing component (mARC).

  Chemical research in toxicology 20141020

• Glycogen synthase kinase 3 regulates cell death and survival signaling in tumor cells under redox stress.

  Neoplasia (New York, N.Y.) 20140901

• Novel three-component Rieske non-heme iron oxygenase system catalyzing the N-dealkylation of chloroacetanilide herbicides in sphingomonads DC-6 and DC-2.

  Applied and environmental microbiology 20140801

• Effect of resveratrol on mitochondrial function: implications in parkin-associated familiar Parkinson's disease.

  Biochimica et biophysica acta 20140701

• NAD(+) administration decreases doxorubicin-induced liver damage of mice by enhancing antioxidation capacity and decreasing DNA damage.

  Chemico-biological interactions 20140405

• Toxicological properties of the thiolated inorganic arsenic and arsenosugar metabolite thio-dimethylarsinic acid in human bladder cells.

  Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20140401

• Caspase inhibition augments Dichlorvos-induced dopaminergic neuronal cell death by increasing ROS production and PARP1 activation.

  Neuroscience 20140131

• Biochemical properties of human dehydrogenase/reductase (SDR family) member 7.

  Chemico-biological interactions 20140125

• Resveratrol delays Wallerian degeneration in a NAD(+) and DBC1 dependent manner.

  Experimental neurology 20140101

• Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay.

  Biochemistry 20131223

• Resveratrol induces a mitochondrial complex I-dependent increase in NADH oxidation responsible for sirtuin activation in liver cells.

  The Journal of biological chemistry 20131220

• Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT.

  Aging cell 20131201

• Disturbance of aerobic metabolism accompanies neurobehavioral changes induced by nickel in mice.

  Neurotoxicology 20130901

• Cofactor balance by nicotinamide nucleotide transhydrogenase (NNT) coordinates reductive carboxylation and glucose catabolism in the tricarboxylic acid (TCA) cycle.

  The Journal of biological chemistry 20130503

• Structural and functional characterization of a plant S-nitrosoglutathione reductase from Solanum lycopersicum.

  Biochimie 20130401

• Homoisocitrate dehydrogenase from Candida albicans: properties, inhibition, and targeting by an antifungal pro-drug.

  FEMS yeast research 20130301

• Retinoic acid biosynthesis catalyzed by retinal dehydrogenases relies on a rate-limiting conformational transition associated with substrate recognition.

  Chemico-biological interactions 20130225

• Inhibition of human alcohol and aldehyde dehydrogenases by cimetidine and assessment of its effects on ethanol metabolism.

  Chemico-biological interactions 20130225

• New enzymatic assay for the AKR1C enzymes.

  Chemico-biological interactions 20130225

• Biocatalytic production of alpha-hydroxy ketones and vicinal diols by yeast and human aldo-keto reductases.

  Chemico-biological interactions 20130225

• Catalytic contribution of threonine 244 in human ALDH2.

  Chemico-biological interactions 20130225

• Fluorescence lifetime analysis and effect of magnesium ions on binding of NADH to human aldehyde dehydrogenase 1.

  Chemico-biological interactions 20130225

• A paradoxical method for NAD+/NADH accumulation on an electrode surface using a hydrophobic ionic liquid.

  Biosensors & bioelectronics 20130115

• Mitochondrial inhibitor models of Huntington's disease and Parkinson's disease induce zinc accumulation and are attenuated by inhibition of zinc neurotoxicity in vitro or in vivo.

  Neuro-degenerative diseases 20130101

• Regulation of FOXOs and p53 by SIRT1 modulators under oxidative stress.

  PloS one 20130101

• Development of a satisfactory and general continuous assay for aminotransferases by coupling with (R)-2-hydroxyglutarate dehydrogenase.

  Analytical biochemistry 20121215

• Enhancement of tacrolimus productivity in Streptomyces tsukubaensis by the use of novel precursors for biosynthesis.

  Enzyme and microbial technology 20121210

• Influence of vacuum skin packaging on color stability of beef longissimus lumborum compared with vacuum and high-oxygen modified atmosphere packaging.

  Meat science 20121201

• Entamoeba histolytica thioredoxin reductase: molecular and functional characterization of its atypical properties.

  Biochimica et biophysica acta 20121201

• Optical detection of NADH based on biocatalytic growth of Au-Ag core-shell nanoparticles.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121201

• Converting molecular information of redox coenzymes via self-assembly.

  Chemical communications (Cambridge, England) 20121121

• High oxidative capacity and type IIx fibre content in springbok and fallow deer skeletal muscle suggest fast sprinters with a resistance to fatigue.

  The Journal of experimental biology 20121115

• Suppression of electron transfer to dioxygen by charge transfer and electron transfer complexes in the FAD-dependent reductase component of toluene dioxygenase.

  The Journal of biological chemistry 20121102

• Structural diversity of new C13-polyketides produced by Chaetomium mollipilium cultivated in the presence of a NAD(+)-dependent histone deacetylase inhibitor.

  Organic letters 20121102

• Social memory, amnesia, and autism: brain oxytocin secretion is regulated by NAD+ metabolites and single nucleotide polymorphisms of CD38.

  Neurochemistry international 20121101

• Effects of aripiprazole and clozapine on the treatment of glycolytic carbon in PC12 cells.

  Journal of neural transmission (Vienna, Austria : 1996) 20121101

• Pyridine metabolism in tea plants: salvage, conjugate formation and catabolism.

  Journal of plant research 20121101

• Horse liver alcohol dehydrogenase: new perspectives for an old enzyme.

  Molecular biotechnology 20121101

• The redox-sensing protein Rex, a transcriptional regulator of solventogenesis in Clostridium acetobutylicum.

  Applied microbiology and biotechnology 20121101

• Characterization of glycine substitution mutations within the putative NAD+-binding site of Bacillus licheniformis aldehyde dehydrogenase.

  Protein and peptide letters 20121101

• S-Mercuration of rat sorbitol dehydrogenase by methylmercury causes its aggregation and the release of the zinc ion from the active site.

  Archives of toxicology 20121101

• Crystal structures of rice (Oryza sativa) glyceraldehyde-3-phosphate dehydrogenase complexes with NAD and sulfate suggest involvement of Phe37 in NAD binding for catalysis.

  Plant molecular biology 20121101

• Effect of mycophenolic acid on trans-plasma membrane electron transport and electric potential in virus-infected plant tissue.

  Plant physiology and biochemistry : PPB 20121101

• A second target of benzamide riboside: dihydrofolate reductase.

  Cancer biology & therapy 20121101

• Comparison of the formation of nicotinic acid conjugates in leaves of different plant species.

  Plant physiology and biochemistry : PPB 20121101

• Propofol improves recovery of the isolated working hypertrophic heart from ischaemia-reperfusion.

  Pflugers Archiv : European journal of physiology 20121101

• Engineering catalytic properties and thermal stability of plant formate dehydrogenase by single-point mutations.

  Protein engineering, design & selection : PEDS 20121101

• Alcohol metabolism.

  Clinics in liver disease 20121101

• High-throughput synthesis and electrochemical screening of a library of modified electrodes for NADH oxidation.

  Journal of the American Chemical Society 20121031

• Identification of Tyr241 as a key catalytic base in the family 4 glycoside hydrolase BglT from Thermotoga maritima.

  Biochemistry 20121023

• Electrochemistry of Q-graphene.

  Nanoscale 20121021

• Oxygen-initiated chain mechanism for hydride transfer between NADH and NAD+ models. Reaction of 1-benzyl-3-cyanoquinolinium ion with N-methyl-9,10-dihydroacridine in acetonitrile.

  The Journal of organic chemistry 20121019

• Grafted Azure A modified electrodes as disposable β-nicotinamide adenine dinucleotide sensors.

  Analytica chimica acta 20121017

• Regulation of NAD(H) pool and NADH/NAD(+) ratio by overexpression of nicotinic acid phosphoribosyltransferase for succinic acid production in Escherichia coli NZN111.

  Enzyme and microbial technology 20121010

• Metabolic consequences of NDUFS4 gene deletion in immortalized mouse embryonic fibroblasts.

  Biochimica et biophysica acta 20121001

• Mitochondrial hydrogen peroxide production as determined by the pyridine nucleotide pool and its redox state.

  Biochimica et biophysica acta 20121001

• From in silico to in spectro kinetics of respiratory complex I.

  Biochimica et biophysica acta 20121001

• Altered cofactor binding affects stability and activity of human UDP-galactose 4'-epimerase: implications for type III galactosemia.

  Biochimica et biophysica acta 20121001

• An improved method of xylose utilization by recombinant Saccharomyces cerevisiae.

  Journal of industrial microbiology & biotechnology 20121001

• Administration of a murine diet supplemented with conjugated linoleic acid increases the expression and activity of hepatic uncoupling proteins.

  Journal of bioenergetics and biomembranes 20121001

• Kinetic involvement of acetaldehyde substrate inhibition on the rate equation of yeast aldehyde dehydrogenase.

  Applied biochemistry and biotechnology 20121001

• Neuronal and extraneuronal release of ATP and NAD(+) in smooth muscle.

  IUBMB life 20121001

• High-resolution structures of Thermus thermophilus enoyl-acyl carrier protein reductase in the apo form, in complex with NAD+ and in complex with NAD+ and triclosan.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20121001

• Immobilization of a mediator onto carbon cloth electrode and employment of the modified electrode to an electroenzymatic bioreactor.

  Journal of microbiology and biotechnology 20121001

• NAD+ biosynthesis ameliorates a zebrafish model of muscular dystrophy.

  PLoS biology 20121001

• Comparative analysis of two glyceraldehyde-3-phosphate dehydrogenases from a thermoacidophilic archaeon, Sulfolobus tokodaii.

  FEBS letters 20120921

• Enzyme biosensor for androsterone based on 3α-hydroxysteroid dehydrogenase immobilized onto a carbon nanotubes/ionic liquid/NAD+ composite electrode.

  Talanta 20120915

• Protein engineering of a thermostable polyol dehydrogenase.

  Enzyme and microbial technology 20120910

• Synthesis of carba-NAD and the structures of its ternary complexes with SIRT3 and SIRT5.

  The Journal of organic chemistry 20120907

• ¹³C magnetic resonance spectroscopy detection of changes in serine isotopomers reflects changes in mitochondrial redox status.

  Magnetic resonance in medicine 20120901

• Metaboloepigenetics: interrelationships between energy metabolism and epigenetic control of gene expression.

  Journal of cellular physiology 20120901

• NAD(+) biosynthesis and salvage--a phylogenetic perspective.

  The FEBS journal 20120901

• SLO2, a mitochondrial pentatricopeptide repeat protein affecting several RNA editing sites, is required for energy metabolism.

  The Plant journal : for cell and molecular biology 20120901

• Induction of the mitochondrial permeability transition (MPT) by micromolar iron: liberation of calcium is more important than NAD(P)H oxidation.

  Biochimica et biophysica acta 20120901

• Regioselective synthesis of 1,3,5-adamantanetriol from 1,3-adamantanediol using Kitasatospora cells.

  Biotechnology letters 20120901

• A Class I UV-blocking (senofilcon A) soft contact lens prevents UVA-induced yellow fluorescence and NADH loss in the rabbit lens nucleus in vivo.

  Experimental eye research 20120901

• An increase in the redox state during reperfusion contributes to the cardioprotective effect of GIK solution.

  Journal of applied physiology (Bethesda, Md. : 1985) 20120901

• The absence of alternative oxidase AOX1A results in altered response of photosynthetic carbon assimilation to increasing CO(2) in Arabidopsis thaliana.

  Plant & cell physiology 20120901

• Increased oxidative stress and anaerobic energy release, but blunted Thr172-AMPKα phosphorylation, in response to sprint exercise in severe acute hypoxia in humans.

  Journal of applied physiology (Bethesda, Md. : 1985) 20120901

• Characterization of glycolytic metabolism and ion transport of Candida albicans.

  Yeast (Chichester, England) 20120901

• Haem oxygenase-1 is involved in salicylic acid-induced alleviation of oxidative stress due to cadmium stress in Medicago sativa.

  Journal of experimental botany 20120901

• Determinants of brain cell metabolic phenotypes and energy substrate utilization unraveled with a modeling approach.

  PLoS computational biology 20120901

• A model reaction assesses contribution of H-tunneling and coupled motions to enzyme catalysis.

  The Journal of organic chemistry 20120817

• Overview of pyridine nucleotides review series.

  Circulation research 20120817

• Regulation of cell survival and death by pyridine nucleotides.

  Circulation research 20120817

• Pyridine nucleotide regulation of cardiac intermediary metabolism.

  Circulation research 20120817

• Sirtuins and pyridine nucleotides.

  Circulation research 20120817

• Splice variants of the P2X7 receptor reveal differential agonist dependence and functional coupling with pannexin-1.

  Journal of cell science 20120815

• Online enzyme discrimination and determination of substrate enantiomers based on electrophoretically mediated microanalysis.

  Analytical chemistry 20120807

• Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes.

  Biochemistry 20120807

• Comparative study of C^N and N^C type cyclometalated ruthenium complexes with a NAD+/NADH function.

  Inorganic chemistry 20120806

• Theaflavins inhibit the ATP synthase and the respiratory chain without increasing superoxide production.

  The Journal of nutritional biochemistry 20120801

• Modulation of ethanol stress tolerance by aldehyde dehydrogenase in the mycorrhizal fungus Tricholoma vaccinum.

  Mycorrhiza 20120801

• NAD(+)/NADH and skeletal muscle mitochondrial adaptations to exercise.

  American journal of physiology. Endocrinology and metabolism 20120801

• In situ regeneration of NADH via lipoamide dehydrogenase-catalyzed electron transfer reaction evidenced by spectroelectrochemistry.

  Bioelectrochemistry (Amsterdam, Netherlands) 20120801

• Decarboxylation mechanisms in biological system.

  Bioorganic chemistry 20120801

• Elucidating and reprogramming Escherichia coli metabolisms for obligate anaerobic n-butanol and isobutanol production.

  Applied microbiology and biotechnology 20120801

• From steady-state to synchronized yeast glycolytic oscillations II: model validation.

  The FEBS journal 20120801

• Coenzyme depletion by members of the aerolysin family of pore-forming toxins leads to diminished ATP levels and cell death.

  Molecular bioSystems 20120801

• Constructing spatially separated multienzyme system through bioadhesion-assisted bio-inspired mineralization for efficient carbon dioxide conversion.

  Bioresource technology 20120801

• L-myo-inositol-1-phosphate synthase expressed in developing organ: isolation and characterisation of the enzyme from human fetal liver.

  Applied biochemistry and biotechnology 20120801

• From steady-state to synchronized yeast glycolytic oscillations I: model construction.

  The FEBS journal 20120801

• Redox state alters anti-cancer effects of wedelolactone.

  Environmental and molecular mutagenesis 20120801

• Effect of 635 nm light-emitting diode irradiation on intracellular superoxide anion scavenging independent of the cellular enzymatic antioxidant system.

  Photomedicine and laser surgery 20120801

• Engineering a homobutanol fermentation pathway in Escherichia coli EG03.

  Journal of industrial microbiology & biotechnology 20120801

• Inhibition of mitochondrial complex I by various non-steroidal anti-inflammatory drugs and its protection by quercetin via a coenzyme Q-like action.

  Chemico-biological interactions 20120730

• The C-terminal domain of 4-hydroxyphenylacetate 3-hydroxylase from Acinetobacter baumannii is an autoinhibitory domain.

  The Journal of biological chemistry 20120727

• Intracellular β-nicotinamide adenine dinucleotide inhibits the skeletal muscle ClC-1 chloride channel.

  The Journal of biological chemistry 20120727

• NAD+-dependent sirtuin 1 and 6 proteins coordinate a switch from glucose to fatty acid oxidation during the acute inflammatory response.

  The Journal of biological chemistry 20120727

• Terpenylated coumarins as SIRT1 activators isolated from Ailanthus altissima.

  Journal of natural products 20120727

• Ultrasensitive detection of the reduced form of nicotinamide adenine dinucleotide based on carbon nanotube field effect transistor.

  The Analyst 20120721

• The role of glycine residues 140 and 141 of subunit B in the functional ubiquinone binding site of the Na+-pumping NADH:quinone oxidoreductase from Vibrio cholerae.

  The Journal of biological chemistry 20120720

• Catalytic mechanism of human UDP-glucose 6-dehydrogenase: in situ proton NMR studies reveal that the C-5 hydrogen of UDP-glucose is not exchanged with bulk water during the enzymatic reaction.

  Carbohydrate research 20120715

• The three-dimensional structural basis of type II hyperprolinemia.

  Journal of molecular biology 20120713

• Confirmation of Frm2 as a novel nitroreductase in Saccharomyces cerevisiae.

  Biochemical and biophysical research communications 20120713

• Role of deleted in breast cancer 1 (DBC1) protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase.

  The Journal of biological chemistry 20120706

• Multianalyte digital enzyme biosensors with built-in Boolean logic.

  Analytical chemistry 20120703

• Coenzyme preference of Streptococcus pyogenes δ1-pyrroline-5-carboxylate reductase: evidence supporting NADPH as the physiological electron donor.

  Amino acids 20120701

• Decolorization of textile dyes by Alishewanella sp. KMK6.

  Applied microbiology and biotechnology 20120701

• Identification of a major enzyme for the synthesis and hydrolysis of cyclic ADP-ribose in amphibian cells and evolutional conservation of the enzyme from human to invertebrate.

  Molecular and cellular biochemistry 20120701

• The cofactor preference of glucose-6-phosphate dehydrogenase from Escherichia coli--modeling the physiological production of reduced cofactors.

  The FEBS journal 20120701

• A dual role for poly(ADP-ribose) polymerase-1 during caspase-dependent apoptosis.

  Toxicological sciences : an official journal of the Society of Toxicology 20120701

• A glucose bio-battery prototype based on a GDH/poly(methylene blue) bioanode and a graphite cathode with an iodide/tri-iodide redox couple.

  Bioresource technology 20120701

• A constraint-based model analysis of the metabolic consequences of increased NADPH oxidation in Saccharomyces cerevisiae.

  Metabolic engineering 20120701

• Cross-linked protein complex exhibiting asymmetric oxidation activities in the absence of added cofactor.

  Biotechnology progress 20120701

• Crystallization and preliminary X-ray diffraction analysis of the high molecular weight ketoacyl reductase FabG4 complexed with NADH.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20120701

• Structural and enzymatic analyses reveal the binding mode of a novel series of Francisella tularensis enoyl reductase (FabI) inhibitors.

  Journal of medicinal chemistry 20120628

• Oxidative phosphorylation, not glycolysis, powers presynaptic and postsynaptic mechanisms underlying brain information processing.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20120627

• Visible light-driven NADH regeneration sensitized by proflavine for biocatalysis.

  Chembiochem : a European journal of chemical biology 20120618

• Friedreich's ataxia reveals a mechanism for coordinate regulation of oxidative metabolism via feedback inhibition of the SIRT3 deacetylase.

  Human molecular genetics 20120615

• An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis.

  Cancer research 20120615

• Isonicotinamide enhances Sir2 protein-mediated silencing and longevity in yeast by raising intracellular NAD+ concentration.

  The Journal of biological chemistry 20120615

• NAD+ levels control Ca2+ store replenishment and mitogen-induced increase of cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes.

  The Journal of biological chemistry 20120615

• Biochemical characterization and substrate profiling of a new NADH-dependent enoate reductase from Lactobacillus casei.

  Enzyme and microbial technology 20120610

• Elucidation of post-PKS tailoring steps involved in landomycin biosynthesis.

  Organic & biomolecular chemistry 20120607

• Estradiol acutely suppresses inhibition in the hippocampus through a sex-specific endocannabinoid and mGluR-dependent mechanism.

  Neuron 20120607

• Hydrogen evolution from aliphatic alcohols and 1,4-selective hydrogenation of NAD+ catalyzed by a [C,N] and a [C,C] cyclometalated organoiridium complex at room temperature in water.

  Journal of the American Chemical Society 20120606

• The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.

  Cell metabolism 20120606

• Inhibition of nicotinamide phosphoribosyltransferase modifies LPS-induced inflammatory responses of human monocytes.

  Innate immunity 20120601

• Nanotube-supported bioproduction of 4-hydroxy-2-butanone via in situ cofactor regeneration.

  Applied microbiology and biotechnology 20120601

• Solution NMR spectroscopic characterization of human VDAC-2 in detergent micelles and lipid bilayer nanodiscs.

  Biochimica et biophysica acta 20120601

• Cell death, non-invasively assessed by intrinsic fluorescence intensity of NADH, is a predictive indicator of functional differentiation of embryonic stem cells.

  Biology of the cell 20120601

• Identification of novel components of NAD-utilizing metabolic pathways and prediction of their biochemical functions.

  Molecular bioSystems 20120601

• Prevention of acute/severe hypoglycemia-induced neuron death by lactate administration.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120601

• Synthesis of silica particles and their application as supports for alcohol dehydrogenases and cofactor immobilizations: conformational changes that lead to switch in enzyme stereoselectivity.

  Biochimica et biophysica acta 20120601

• Bacteriohemerythrin bolsters the activity of the particulate methane monooxygenase (pMMO) in Methylococcus capsulatus (Bath).

  Journal of inorganic biochemistry 20120601

• EPR and potentiometric studies of copper(II) binding to nicotinamide adenine dinucleotide (NAD+) in water solution.

  Journal of inorganic biochemistry 20120601

• Differential fumarate binding to Arabidopsis NAD+-malic enzymes 1 and -2 produces an opposite activity modulation.

  Biochimie 20120601

• Nicotinamide-induced mitophagy: event mediated by high NAD+/NADH ratio and SIRT1 protein activation.

  The Journal of biological chemistry 20120601

• The peroxisomal NAD+ carrier of Arabidopsis thaliana transports coenzyme A and its derivatives.

  Journal of bioenergetics and biomembranes 20120601

• Design, synthesis and biological evaluation of potent NAD+-dependent DNA ligase inhibitors as potential antibacterial agents. Part 2: 4-amino-pyrido[2,3-d]pyrimidin-5(8H)-ones.

  Bioorganic & medicinal chemistry letters 20120601

• Design, synthesis and biological evaluation of potent NAD+-dependent DNA ligase inhibitors as potential antibacterial agents. Part I: aminoalkoxypyrimidine carboxamides.

  Bioorganic & medicinal chemistry letters 20120601

• SIRT1 is required for the effects of rapamycin on high glucose-inducing mesangial cells senescence.

  Mechanisms of ageing and development 20120601

• Coenzyme regeneration in hexanol oxidation catalyzed by alcohol dehydrogenase.

  Applied biochemistry and biotechnology 20120601

• Improvement of hydrogen productivity by introduction of NADH regeneration pathway in Clostridium paraputrificum.

  Applied biochemistry and biotechnology 20120601

• Stokes shift spectroscopy pilot study for cancerous and normal prostate tissues.

  Applied optics 20120601

• Presence of bound substrate in lactate dehydrogenase from carp liver.

  Indian journal of biochemistry & biophysics 20120601

• Reduction kinetics of 3-hydroxybenzoate 6-hydroxylase from Rhodococcus jostii RHA1.

  Biochemistry 20120529

• Crystal structures of phosphite dehydrogenase provide insights into nicotinamide cofactor regeneration.

  Biochemistry 20120529

• Electron transfer in subunit NuoI (TYKY) of Escherichia coli NADH:quinone oxidoreductase (NDH-1).

  The Journal of biological chemistry 20120518

• A TEMPO-conjugated fluorescent probe for monitoring mitochondrial redox reactions.

  Chemical communications (Cambridge, England) 20120518

• P2X7 receptor-mediated purinergic signaling promotes liver injury in acetaminophen hepatotoxicity in mice.

  American journal of physiology. Gastrointestinal and liver physiology 20120515

• Sensitive colorimetric visualization of dihydronicotinamide adenine dinucleotide based on anti-aggregation of gold nanoparticles via boronic acid-diol binding.

  Biosensors & bioelectronics 20120515

• A single tyrosine hydroxyl group almost entirely controls the NADPH specificity of Plasmodium falciparum ferredoxin-NADP+ reductase.

  Biochemistry 20120508

• SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function.

  Cell metabolism 20120502

• Anti-inflammatory mechanism of taurine against ischemic stroke is related to down-regulation of PARP and NF-κB.

  Amino acids 20120501

• Overexpression of SIRT6 in porcine fetal fibroblasts attenuates cytotoxicity and premature senescence caused by D-galactose and tert-butylhydroperoxide.

  DNA and cell biology 20120501

• Accumulation of pyruvate by changing the redox status in Escherichia coli.

  Biotechnology letters 20120501

• Influence of ethanol extract of Ginkgo biloba leaves on the isolated rat heart work and mitochondria functions.

  Journal of cardiovascular pharmacology 20120501

• Inducible NAD overproduction in Arabidopsis alters metabolic pools and gene expression correlated with increased salicylate content and resistance to Pst-AvrRpm1.

  The Plant journal : for cell and molecular biology 20120501

• Prediction of nicotinamide adenine dinucleotide interacting sites based on ensemble support vector machine.

  Protein and peptide letters 20120501

• Mitochondrial respiration in ME-CAM, PEPCK-CAM, and C₃ succulents: comparative operation of the cytochrome, alternative, and rotenone-resistant pathways.

  Journal of experimental botany 20120501

• Amino acid substitutions at glutamate-354 in dihydrolipoamide dehydrogenase of Escherichia coli lower the sensitivity of pyruvate dehydrogenase to NADH.

  Microbiology (Reading, England) 20120501

• Asymmetric synthesis of (R)-1,3-butanediol from 4-hydroxy-2-butanone by a newly isolated strain Candida krusei ZJB-09162.

  Applied microbiology and biotechnology 20120501

• Annotation and analysis of malic enzyme genes encoding for multiple isoforms in the fungus Mucor circinelloides CBS 277.49.

  Biotechnology letters 20120501

• Effects of exogenous hydrogen sulphide on calcium signalling, background (TASK) K channel activity and mitochondrial function in chemoreceptor cells.

  Pflugers Archiv : European journal of physiology 20120501

• Molecular dynamics simulations of the coenzyme induced conformational changes of Mycobacterium tuberculosis L-alanine dehydrogenase.

  Journal of molecular graphics & modelling 20120501

• Control of D-octopine formation in scallop adductor muscle as revealed through thermodynamic studies of octopine dehydrogenase.

  The Journal of experimental biology 20120501

• Effects of NADH-preferring xylose reductase expression on ethanol production from xylose in xylose-metabolizing recombinant Saccharomyces cerevisiae.

  Journal of biotechnology 20120430

• Analysis and prediction of the physiological effects of altered coenzyme specificity in xylose reductase and xylitol dehydrogenase during xylose fermentation by Saccharomyces cerevisiae.

  Journal of biotechnology 20120430

• A reversible early oxidized redox state that precedes macromolecular ROS damage in aging nontransgenic and 3xTg-AD mouse neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20120425

• Analysis of biomarkers characteristic of porcine liver injury--from biomolecular logic gates to an animal model.

  The Analyst 20120421

• NAMPT pathway is involved in the FOXO3a-mediated regulation of GADD45A expression.

  Biochemical and biophysical research communications 20120420

• Organometallic ruthenium and iridium transfer-hydrogenation catalysts using coenzyme NADH as a cofactor.

  Angewandte Chemie (International ed. in English) 20120416

• A flavoprotein monooxygenase that catalyses a Baeyer-Villiger reaction and thioether oxidation using NADH as the nicotinamide cofactor.

  Chembiochem : a European journal of chemical biology 20120416

• SIRT3 gene expression: a link between inherited mitochondrial DNA variants and oxidative stress.

  Gene 20120415

• Adenosine 5-diphosphate-ribose is a neural regulator in primate and murine large intestine along with β-NAD(+).

  The Journal of physiology 20120415

• Probing the NADH- and Methyl Red-binding site of a FMN-dependent azoreductase (AzoA) from Enterococcus faecalis.

  Archives of biochemistry and biophysics 20120415

• Micro-coulometric study of bioelectrochemical reaction coupled with TCA cycle.

  Biosensors & bioelectronics 20120415

• Crystal structure of binary and ternary complexes of archaeal UDP-galactose 4-epimerase-like L-threonine dehydrogenase from Thermoplasma volcanium.

  The Journal of biological chemistry 20120413

• Fluorescence properties of carba nicotinamide adenine dinucleotide for glucose sensing.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20120410

• Role of mitochondrial Ca2+ in the regulation of cellular energetics.

  Biochemistry 20120410

• Cloning and characterization of a thermostable H2O-forming NADH oxidase from Lactobacillus rhamnosus.

  Enzyme and microbial technology 20120405

• Identification, Isolation and characterization of a novel azoreductase from Clostridium perfringens.

  Anaerobe 20120401

• The human gene SLC25A17 encodes a peroxisomal transporter of coenzyme A, FAD and NAD+.

  The Biochemical journal 20120401

• Mechanism of increased respiration in an H+-ATPase-defective mutant of Corynebacterium glutamicum.

  Journal of bioscience and bioengineering 20120401

• Quercetin treatment changes fluxes in the primary metabolism and increases culture longevity and recombinant α₁-antitrypsin production in human AGE1.HN cells.

  Applied microbiology and biotechnology 20120401

• Development of a continuous assay and steady-state characterization of Escherichia coli threonine synthase.

  Analytical biochemistry 20120401

• NdnR is an NAD-responsive transcriptional repressor of the ndnR operon involved in NAD de novo biosynthesis in Corynebacterium glutamicum.

  Microbiology (Reading, England) 20120401

• The PPARα agonists fenofibrate and CP-778875 cause increased β-oxidation, leading to oxidative injury in skeletal and cardiac muscle in the rat.

  Toxicologic pathology 20120401

• Novel metabolic aspects related to adenosine deaminase inhibition in a human astrocytoma cell line.

  Neurochemistry international 20120401

• Sirtuins as regulators of metabolism and healthspan.

  Nature reviews. Molecular cell biology 20120401

• Presence and removal of a contaminating NADH oxidation activity in recombinant maltose-binding protein fusion proteins expressed in Escherichia coli.

  BioTechniques 20120401

• Optical imaging of tissue mitochondrial redox state in intact rat lungs in two models of pulmonary oxidative stress.

  Journal of biomedical optics 20120401

• Leishmania infantum nicotinamidase is required for late-stage development in its natural sand fly vector, Phlebotomus perniciosus.

  International journal for parasitology 20120401

• Purification and characterization of a hexanol-degrading enzyme extracted from apple.

  Journal of agricultural and food chemistry 20120328

• Identification of novel S-adenosyl-L-homocysteine hydrolase inhibitors through homology-model-based virtual screening, synthesis, and biological evaluation.

  Journal of chemical information and modeling 20120326

• NAD(+) administration decreases ischemic brain damage partially by blocking autophagy in a mouse model of brain ischemia.

  Neuroscience letters 20120323

• Nmnat2 protects cardiomyocytes from hypertrophy via activation of SIRT6.

  FEBS letters 20120323

• Temperature-responsive polymer/carbon nanotube hybrids: smart conductive nanocomposite films for modulating the bioelectrocatalysis of NADH.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20120319

• Differences in susceptibility to inactivation of human aldehyde dehydrogenases by lipid peroxidation byproducts.

  Chemical research in toxicology 20120319

• Low potential detection of NADH based on Fe₃O₄ nanoparticles/multiwalled carbon nanotubes composite: fabrication of integrated dehydrogenase-based lactate biosensor.

  Biosensors & bioelectronics 20120315

• Simultaneous detection of NADH and H₂O₂ using flow injection analysis based on a bifunctional poly(thionine)-modified electrode.

  Biosensors & bioelectronics 20120315

• Carbon nanotubes-ionic liquid nanocomposites sensing platform for NADH oxidation and oxygen, glucose detection in blood.

  Talanta 20120315

• RpoS proteolysis is controlled directly by ATP levels in Escherichia coli.

  Genes & development 20120315

• Rebamipide suppresses diclofenac-induced intestinal permeability via mitochondrial protection in mice.

  World journal of gastroenterology 20120314

• Direct intercalation of bis-2,2',2″,6-terpyridylcobalt(III) into zirconium phosphate layers for biosensing applications.

  Langmuir : the ACS journal of surfaces and colloids 20120306

• Magnetic nano-Fe3O4-supported 1-benzyl-1,4-dihydronicotinamide (BNAH): synthesis and application in the catalytic reduction of α,β-epoxy ketones.

  Organic letters 20120302

• Identification and partial characterization of Rhizopus nigricans Gβ proteins and their expression in the presence of progesterone.

  The Journal of steroid biochemistry and molecular biology 20120301

• Molecular docking and structural analysis of cofactor-protein interaction between NAD⁺ and 11β-hydroxysteroid dehydrogenase type 2.

  Journal of molecular modeling 20120301

• Modulatory effect of resveratrol on SIRT1, SIRT3, SIRT4, PGC1α and NAMPT gene expression profiles in wild-type adult zebrafish liver.

  Molecular biology reports 20120301

• Studies with low micromolar levels of ascorbic and dehydroascorbic acid fail to unravel a preferential route for vitamin C uptake and accumulation in U937 cells.

  The British journal of nutrition 20120301

• Gene cloning, expression, and characterization of a novel acetaldehyde dehydrogenase from Issatchenkia terricola strain XJ-2.

  Applied microbiology and biotechnology 20120301

• Effects of 4-hydroxy-2-nonenal on beef heart mitochondrial ultrastructure, oxygen consumption, and metmyoglobin reduction.

  Meat science 20120301

• Enhanced charge-independent mitochondrial free Ca(2+) and attenuated ADP-induced NADH oxidation by isoflurane: Implications for cardioprotection.

  Biochimica et biophysica acta 20120301

• Mitochondrial oxidative stress and epilepsy in SOD2 deficient mice: attenuation by a lipophilic metalloporphyrin.

  Neurobiology of disease 20120301

• Functional annotation and characterization of 3-hydroxybenzoate 6-hydroxylase from Rhodococcus jostii RHA1.

  Biochimica et biophysica acta 20120301

• A mutant in the ADH1 gene of Chlamydomonas reinhardtii elicits metabolic restructuring during anaerobiosis.

  Plant physiology 20120301

• Ca²⁺ signals of astrocytes are modulated by the NAD⁺/NADH redox state.

  Journal of neurochemistry 20120301

• DNA damage in Nijmegen Breakage Syndrome cells leads to PARP hyperactivation and increased oxidative stress.

  PLoS genetics 20120301

• [Nicorandil and ulceration: a physiopathological hypothesis].

  Annales de dermatologie et de venereologie 20120301

• Electrocatalysis for the oxidation of NADH based on beta-cyclodextrin/multi-walled carbon nanotubes modified ITO electrode.

  Journal of nanoscience and nanotechnology 20120301

• Unusual NADPH conformation in the crystal structure of a cinnamyl alcohol dehydrogenase from Helicobacter pylori in complex with NADP(H) and substrate docking analysis.

  FEBS letters 20120217

• Durable cofactor immobilization in sol-gel bio-composite thin films for reagentless biosensors and bioreactors using dehydrogenases.

  Biosensors & bioelectronics 20120215

• Malate-aspartate shuttle and exogenous NADH/cytochrome c electron transport pathway as two independent cytosolic reducing equivalent transfer systems.

  Archives of biochemistry and biophysics 20120215

• Electrocatalytic oxidation of NADH at electrogenerated NAD+ oxidation product immobilized onto multiwalled carbon nanotubes/ionic liquid nanocomposite: application to ethanol biosensing.

  Talanta 20120215

• Engineered NADH-dependent GRE2 from Saccharomyces cerevisiae by directed enzyme evolution enhances HMF reduction using additional cofactor NADPH.

  Enzyme and microbial technology 20120210

• Nanoporous carbon materials for electrochemical sensing.

  Chemistry, an Asian journal 20120206

• Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases.

  Cell 20120203

• Characterization of human nicotinate phosphoribosyltransferase: Kinetic studies, structure prediction and functional analysis by site-directed mutagenesis.

  Biochimie 20120201

• Identification of important residues in diketoreductase from Acinetobacter baylyi by molecular modeling and site-directed mutagenesis.

  Biochimie 20120201

• A modular system for regeneration of NAD cofactors using graphite particles modified with hydrogenase and diaphorase moieties.

  Chemical communications (Cambridge, England) 20120201

• Functionalized gold nanoparticles and films stabilized by in situ formed polyeugenol.

  Colloids and surfaces. B, Biointerfaces 20120201

• Abamectin affects the bioenergetics of liver mitochondria: A potential mechanism of hepatotoxicity.

  Toxicology in vitro : an international journal published in association with BIBRA 20120201

• Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis.

  Biochimica et biophysica acta 20120201

• Crystal structure of NAD+-dependent Peptoniphilus asaccharolyticus glutamate dehydrogenase reveals determinants of cofactor specificity.

  Journal of structural biology 20120201

• The interplay between sulphur and selenium metabolism influences the intracellular redox balance in Saccharomyces cerevisiae.

  FEMS yeast research 20120201

• Characterization of covalent Ene adduct intermediates in 'hydride equivalent' transfers in a dihydropyridine model for NADH reduction reactions.

  Bioorganic chemistry 20120201

• Reduced mitochondrial Ca2+ loading and improved functional recovery after ischemia-reperfusion injury in old vs. young guinea pig hearts.

  American journal of physiology. Heart and circulatory physiology 20120201

• In vitro reduction of hexavalent chromium by cytoplasmic fractions of Pannonibacter phragmitetus LSSE-09 under aerobic and anaerobic conditions.

  Applied biochemistry and biotechnology 20120201

• Structural and functional properties of glycerol-3-phosphate dehydrogenase from a mammalian hibernator.

  The protein journal 20120201

• NAD+ metabolism and NAD(+)-dependent enzymes: promising therapeutic targets for neurological diseases.

  Current drug targets 20120201

• Heterologous expression and mechanistic investigation of a fungal cytochrome P450 (CYP5150A2): involvement of alternative redox partners.

  Archives of biochemistry and biophysics 20120201

• Metabolic control of Clostridium thermocellum via inhibition of hydrogenase activity and the glucose transport rate.

  Applied microbiology and biotechnology 20120201

• Release, neuronal effects and removal of extracellular β-nicotinamide adenine dinucleotide (β-NAD⁺) in the rat brain.

  The European journal of neuroscience 20120201

• Dietary obesity-associated Hif1α activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system.

  Genes & development 20120201

• Purification and characterization of a thermostable glutamate dehydrogenase from a thermophilic bacterium isolated from a sterilization drying oven.

  BMB reports 20120201

• Geranylgeraniol oxidase activity involved in oxidative formation of geranylgeranoic acid in human hepatoma cells.

  Biomedical research (Tokyo, Japan) 20120201

• Evidence in support of lysine 77 and histidine 96 as acid-base catalytic residues in saccharopine dehydrogenase from Saccharomyces cerevisiae.

  Biochemistry 20120131

• Glial hemichannels and their involvement in aging and neurodegenerative diseases.

  Reviews in the neurosciences 20120126

• Structural studies of intermediates along the cyclization pathway of Aplysia ADP-ribosyl cyclase.

  Journal of molecular biology 20120120

• Direct hydride shift mechanism and stereoselectivity of P450nor confirmed by QM/MM calculations.

  The journal of physical chemistry. B 20120119

• The potential of biodetoxification activity as a probiotic property of Lactobacillus reuteri.

  International journal of food microbiology 20120116

• Germline SDHx variants modify breast and thyroid cancer risks in Cowden and Cowden-like syndrome via FAD/NAD-dependant destabilization of p53.

  Human molecular genetics 20120115

• SRP-35, a newly identified protein of the skeletal muscle sarcoplasmic reticulum, is a retinol dehydrogenase.

  The Biochemical journal 20120115

• The level of menadione redox-cycling in pancreatic β-cells is proportional to the glucose concentration: role of NADH and consequences for insulin secretion.

  Toxicology and applied pharmacology 20120115

• Anti-proliferation effect of APO866 on C6 glioblastoma cells by inhibiting nicotinamide phosphoribosyltransferase.

  European journal of pharmacology 20120115

• Synthesis, characterization, and electrochemical applications of carbon nanoparticles derived from castor oil soot.

  Talanta 20120115

• Structural and kinetic evidence that catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates.

  The Journal of biological chemistry 20120113

• Biochemical and structural studies of uncharacterized protein PA0743 from Pseudomonas aeruginosa revealed NAD+-dependent L-serine dehydrogenase.

  The Journal of biological chemistry 20120113

• Size controlled synthesis of biocompatible gold nanoparticles and their activity in the oxidation of NADH.

  Nanotechnology 20120113

• 3-picolyl azide adenine dinucleotide as a probe of femtosecond to picosecond enzyme dynamics.

  The journal of physical chemistry. B 20120112

• Efficient catalytic interconversion between NADH and NAD+ accompanied by generation and consumption of hydrogen with a water-soluble iridium complex at ambient pressure and temperature.

  Journal of the American Chemical Society 20120111

• Structure of the Yersinia pestis FabV enoyl-ACP reductase and its interaction with two 2-pyridone inhibitors.

  Structure (London, England : 1993) 20120111

• In situ chemichromic studies of interactions between a lutetium bis-octaalkyl-substituted phthalocyanine and selected biological cofactors.

  Journal of the Royal Society, Interface 20120107

• Electrocatalytic reaction of hydrogen peroxide and NADH based on poly(neutral red) and FAD hybrid film.

  The Analyst 20120107

• Effect of alternative NAD+-regenerating pathways on the formation of primary and secondary aroma compounds in a Saccharomyces cerevisiae glycerol-defective mutant.

  Applied microbiology and biotechnology 20120101

• Application of a novel thermostable NAD(P)H oxidase from hyperthermophilic archaeon for the regeneration of both NAD⁺ and NADP⁺.

  Biotechnology and bioengineering 20120101

• Pyruvate incubation enhances glycogen stores and sustains neuronal function during subsequent glucose deprivation.

  Neurobiology of disease 20120101

• A peroxisomal carrier delivers NAD⁺ and contributes to optimal fatty acid degradation during storage oil mobilization.

  The Plant journal : for cell and molecular biology 20120101

• Exogenous ornithine is an effective precursor and the δ-ornithine amino transferase pathway contributes to proline accumulation under high N recycling in salt-stressed cashew leaves.

  Journal of plant physiology 20120101

• Redox state-dependent aggregation of mitochondria induced by cytochrome c.

  Molecular and cellular biochemistry 20120101

• The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism.

  The Biochemical journal 20120101

• Crystal structure of glucuronic acid dehydrogenase [correction of dehydrogeanse] from Chromohalobacter salexigens.

  Proteins 20120101

• Coupling of permeabilized cells of Gluconobacter oxydans and Ralstonia eutropha for asymmetric ketone reduction using H2 as reductant.

  Journal of biotechnology 20120101

• Pre-B-cell colony-enhancing factor exerts a neuronal protection through its enzymatic activity and the reduction of mitochondrial dysfunction in in vitro ischemic models.

  Journal of neurochemistry 20120101

• On-line characterization of metabolic state in batch cultivation of Clostridium diolis for 1,3-propanediol production using NADH+H+ fluorescence.

  Applied biochemistry and biotechnology 20120101

• SIRT1, metabolism and cancer.

  Current opinion in oncology 20120101

• Furfural reduction mechanism of a zinc-dependent alcohol dehydrogenase from Cupriavidus necator JMP134.

  Molecular microbiology 20120101

• L-aspartate dehydrogenase: features and applications.

  Applied microbiology and biotechnology 20120101

• Discovery of bacterial NAD⁺-dependent DNA ligase inhibitors: improvements in clearance of adenosine series.

  Bioorganic & medicinal chemistry letters 20120101

• Conserved and specific responses to hypoxia in Aspergillus oryzae and Aspergillus nidulans determined by comparative transcriptomics.

  Applied microbiology and biotechnology 20120101

• Nicotinamide adenine dinucleotide tetrazolium reductase identifies microvasculature activation in muscle from adult patients with dermatomyositis.

  The Journal of rheumatology 20120101

• Host cell and expression engineering for development of an E. coli ketoreductase catalyst: enhancement of formate dehydrogenase activity for regeneration of NADH.

  Microbial cell factories 20120101

• Identifying co-targets to fight drug resistance based on a random walk model.

  BMC systems biology 20120101

• Staurosporine induced poly (ADP-ribose) polymerase independent cell death in Dictyostelium discoideum.

  Indian journal of experimental biology 20120101

• Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter.

  BMC genomics 20120101

• Fungus-mediated green synthesis of silver nanoparticles using Aspergillus terreus.

  International journal of molecular sciences 20120101

• WldS but not Nmnat1 protects dopaminergic neurites from MPP+ neurotoxicity.

  Molecular neurodegeneration 20120101

• NAD+ metabolism and oxidative stress: the golden nucleotide on a crown of thorns.

  Redox report : communications in free radical research 20120101

• Neurodegeneration and motor dysfunction in mice lacking cytosolic and mitochondrial aldehyde dehydrogenases: implications for Parkinson's disease.

  PloS one 20120101

• Cellular autofluorescence following ionizing radiation.

  PloS one 20120101

• Steric effect for proton, hydrogen-atom, and hydride transfer reactions with geometric isomers of NADH-model ruthenium complexes.

  Faraday discussions 20120101

• Deep oxidation of glucose in enzymatic fuel cells through a synthetic enzymatic pathway containing a cascade of two thermostable dehydrogenases.

  Biosensors & bioelectronics 20120101

• Destabilization of the outer and inner mitochondrial membranes by core and linker histones.

  PloS one 20120101

• Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates.

  PloS one 20120101

• Peroxisomal alanine: glyoxylate aminotransferase AGT1 is indispensable for appressorium function of the rice blast pathogen, Magnaporthe oryzae.

  PloS one 20120101

• Fine tuning of the lactate and diacetyl production through promoter engineering in Lactococcus lactis.

  PloS one 20120101

• Integrated detection of intrinsic fluorophores in live microbial cells using an array of thin film amorphous silicon photodetectors.

  Biosensors & bioelectronics 20120101

• Biochemical issues in estimation of cytosolic free NAD/NADH ratio.

  PloS one 20120101

• NAD-independent L-lactate dehydrogenase is required for L-lactate utilization in Pseudomonas stutzeri SDM.

  PloS one 20120101

• Comparative analysis on the key enzymes of the glycerol cycle metabolic pathway in Dunaliella salina under osmotic stresses.

  PloS one 20120101

• Oxidative damage to DNA constituents by iron-mediated Fenton reactions: the deoxyadenosine family.

  Journal of biomolecular structure & dynamics 20120101

• Molecular modeling study for conformational changes of Sirtuin 2 due to substrate and inhibitor binding.

  Journal of biomolecular structure & dynamics 20120101

• Gentamicin rapidly inhibits mitochondrial metabolism in high-frequency cochlear outer hair cells.

  PloS one 20120101

• Altered expression of base excision repair genes in response to high glucose-induced oxidative stress in HepG2 hepatocytes.

  Medical science monitor : international medical journal of experimental and clinical research 20120101

• Genomic insights into syntrophy: the paradigm for anaerobic metabolic cooperation.

  Annual review of microbiology 20120101

• A comparative transcriptomic, fluxomic and metabolomic analysis of the response of Saccharomyces cerevisiae to increases in NADPH oxidation.

  BMC genomics 20120101

• Germline deletion of pantothenate kinases 1 and 2 reveals the key roles for CoA in postnatal metabolism.

  PloS one 20120101

• Alternative splicing of the N-terminal cytosolic and transmembrane domains of P2X7 controls gating of the ion channel by ADP-ribosylation.

  PloS one 20120101

• Age-associated changes in oxidative stress and NAD+ metabolism in human tissue.

  PloS one 20120101

• Glucose is a pH-dependent motor for sperm beat frequency during early activation.

  PloS one 20120101

• Deriving TC50 values of nanoparticles from electrochemical monitoring of lactate dehydrogenase activity indirectly.

  Methods in molecular biology (Clifton, N.J.) 20120101

• Sirt5 deacylation activities show differential sensitivities to nicotinamide inhibition.

  PloS one 20120101

• SIRT1 regulates dendritic development in hippocampal neurons.

  PloS one 20120101

• The PduQ enzyme is an alcohol dehydrogenase used to recycle NAD+ internally within the Pdu microcompartment of Salmonella enterica.

  PloS one 20120101

• A hydrazine coupled cycling assay validates the decrease in redox ratio under starvation in Drosophila.

  PloS one 20120101

• PARP-1 modulation of mTOR signaling in response to a DNA alkylating agent.

  PloS one 20120101

• Late-onset running biphasically improves redox balance, energy- and methylglyoxal-related status, as well as SIRT1 expression in mouse hippocampus.

  PloS one 20120101

• Connexin-43 hemichannels mediate cyclic ADP-ribose generation and its Ca2+-mobilizing activity by NAD+/cyclic ADP-ribose transport.

  The Journal of biological chemistry 20111230

• Protein dynamics and enzymatic chemical barrier passage.

  The journal of physical chemistry. B 20111229

• Tryptophan 697 modulates hydride and interflavin electron transfer in human methionine synthase reductase.

  Biochemistry 20111227

• Nondegradative ubiquitination of apoptosis inducing factor (AIF) by X-linked inhibitor of apoptosis at a residue critical for AIF-mediated chromatin degradation.

  Biochemistry 20111227

• The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+).

  Molecular cell 20111223

• Identification of mitochondrial electron transport chain-mediated NADH radical formation by EPR spin-trapping techniques.

  Biochemistry 20111220

• Detection of cytochrome P450 substrates by using a small-molecule droplet array on an NADH-immobilized solid surface.

  Chembiochem : a European journal of chemical biology 20111216

• What are the differences between ascorbic acid and NADH as hydride and electron sources in vivo on thermodynamics, kinetics, and mechanism?

  The journal of physical chemistry. B 20111215

• Oxygen-independent alkane formation by non-heme iron-dependent cyanobacterial aldehyde decarbonylase: investigation of kinetics and requirement for an external electron donor.

  Biochemistry 20111213

• CVD graphene electrochemistry: biologically relevant molecules.

  Physical chemistry chemical physics : PCCP 20111207

• Structure basis for the regulation of glyceraldehyde-3-phosphate dehydrogenase activity via the intrinsically disordered protein CP12.

  Structure (London, England : 1993) 20111207

• Extremely conserved ATP- or ADP-dependent enzymatic system for nicotinamide nucleotide repair.

  The Journal of biological chemistry 20111202

• Mitochondrial dysfunction and nicotinamide dinucleotide catabolism as mechanisms of cell death and promising targets for neuroprotection.

  Journal of neuroscience research 20111201

• The NAD+ /NADH redox state in astrocytes: independent control of the NAD+ and NADH content.

  Journal of neuroscience research 20111201

• Effects of 2-deoxyglucose and dehydroepiandrosterone on intracellular NAD(+) level, SIRT1 activity and replicative lifespan of human Hs68 cells.

  Biogerontology 20111201

• Identification of a xylose reductase gene in the xylose metabolic pathway of Kluyveromyces marxianus NBRC1777.

  Journal of industrial microbiology & biotechnology 20111201

• NAD+ treatment induces delayed autophagy in Neuro2a cells partially by increasing oxidative stress.

  Neurochemical research 20111201

• A viability assay for Candida albicans based on the electron transfer mediator 2,6-dichlorophenolindophenol.

  Analytical biochemistry 20111201

• Aromatic interactions at atom-to-atom contact and just beyond: a case study of protein interactions of NAD⁺/NADP⁺.

  International journal of biological macromolecules 20111201

• Pharmacological effects of exogenous NAD on mitochondrial bioenergetics, DNA repair, and apoptosis.

  Molecular pharmacology 20111201

• Non-invasive monitoring of cytotoxicity based on kinetic changes of cellular autofluorescence.

  Toxicology in vitro : an international journal published in association with BIBRA 20111201

• Enhanced reducing equivalent generation for 1,3-propanediol production through cofermentation of glycerol and xylose by Klebsiella pneumoniae.

  Applied biochemistry and biotechnology 20111201

• Glyceraldehyde-3-phosphate dehydrogenase as a quinone reductase in the suppression of 1,2-naphthoquinone protein adduct formation.

  Free radical biology & medicine 20111201

• Constitutive SIRT1 overexpression impairs mitochondria and reduces cardiac function in mice.

  Journal of molecular and cellular cardiology 20111201

• Imaging of a glucose analog, calcium and NADH in neurons and astrocytes: dynamic responses to depolarization and sensitivity to pioglitazone.

  Cell calcium 20111201

• Towards the mechanisms involved in the antioxidant action of MnIII [meso-tetrakis(4-N-methyl pyridinium) porphyrin] in mitochondria.

  Journal of bioenergetics and biomembranes 20111201

• WldS enhances insulin transcription and secretion via a SIRT1-dependent pathway and improves glucose homeostasis.

  Diabetes 20111201

• Capacity of bioregulators of stem and progenitor cells to strongly affect liver redox-dependent processes.

  Rejuvenation research 20111201

• Pyridine metabolism and trigonelline synthesis in leaves of the mangrove legume trees Derris indica (Millettia pinnata) and Caesalpinia crista.

  Natural product communications 20111201

• Mutations in the dimer interface of dihydrolipoamide dehydrogenase promote site-specific oxidative damages in yeast and human cells.

  The Journal of biological chemistry 20111118

• Identification of nicotinamide mononucleotide deamidase of the bacterial pyridine nucleotide cycle reveals a novel broadly conserved amidohydrolase family.

  The Journal of biological chemistry 20111118

• Influence of inositol pyrophosphates on cellular energy dynamics.

  Science (New York, N.Y.) 20111111

• Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase.

  Science (New York, N.Y.) 20111111

• Thermodynamic analysis of protein-ligand interactions in complex biological mixtures using a shotgun proteomics approach.

  Journal of proteome research 20111104

• Metabolism of ethanol to acetaldehyde by rat uterine horn subcellular fractions.

  Human & experimental toxicology 20111101

• Biochemical characterization of ethanol-dependent reduction of furfural by alcohol dehydrogenases.

  Biodegradation 20111101

• Cupriavidus necator JMP134 rapidly reduces furfural with a Zn-dependent alcohol dehydrogenase.

  Biodegradation 20111101

• Dynamic modulation of Ca2+ sparks by mitochondrial oscillations in isolated guinea pig cardiomyocytes under oxidative stress.

  Journal of molecular and cellular cardiology 20111101

• Mitochondrial antioxidants alleviate oxidative and nitrosative stress in a cellular model of sepsis.

  Pharmaceutical research 20111101

• Crystal structure of prephenate dehydrogenase from Streptococcus mutans.

  International journal of biological macromolecules 20111101

• Nicotinamide phosphoribosyltransferase (Nampt) affects the lineage fate determination of mesenchymal stem cells: a possible cause for reduced osteogenesis and increased adipogenesis in older individuals.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20111101

• Molecular cloning and characterization of two inducible NAD⁺-adh genes encoding NAD⁺-dependent alcohol dehydrogenases from Acetobacter pasteurianus SKU1108.

  Journal of bioscience and bioengineering 20111101

• Molecular and biochemical characterisation of a Teladorsagia circumcincta glutamate dehydrogenase.

  Experimental parasitology 20111101

• The coenzyme A disulphide reductase of Borrelia burgdorferi is important for rapid growth throughout the enzootic cycle and essential for infection of the mammalian host.

  Molecular microbiology 20111101

• Substrate stereoselectivity of mammalian D-aspartyl endopeptidase.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101

• Phytophthora sojae avirulence effector Avr3b is a secreted NADH and ADP-ribose pyrophosphorylase that modulates plant immunity.

  PLoS pathogens 20111101

• Cloning, expression and characterization of mouse (Mus musculus) nicotinamide 5'-mononucleotide adenylyltransferase-2.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20111101

• Autofluorescence microscopy: a non-destructive tool to monitor mitochondrial toxicity.

  Toxicology letters 20111030

• NADH fluorescence as a photobiological metric in 5-aminolevlinic acid (ALA)-photodynamic therapy.

  Optics express 20111024

• Oxidative damage compromises energy metabolism in the axonal degeneration mouse model of X-adrenoleukodystrophy.

  Antioxidants & redox signaling 20111015

• Pathway analysis of NAD+ metabolism.

  The Biochemical journal 20111015

• Direct electrochemical reduction of graphene oxide on ionic liquid doped screen-printed electrode and its electrochemical biosensing application.

  Biosensors & bioelectronics 20111015

• Substitutions of coenzyme-binding, nonpolar residues improve the low-temperature activity of thermophilic dehydrogenases.

  Biochemistry 20111011

• Engineering the respiratory complex I to energy-converting NADPH:ubiquinone oxidoreductase.

  The Journal of biological chemistry 20111007

• Roles of glucose in photoreceptor survival.

  The Journal of biological chemistry 20111007

• Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice.

  Cell metabolism 20111005

• Imaging cytosolic NADH-NAD(+) redox state with a genetically encoded fluorescent biosensor.

  Cell metabolism 20111005

• Genetically encoded fluorescent sensors for intracellular NADH detection.

  Cell metabolism 20111005

• Enzyme-based NAND gate for rapid electrochemical screening of traumatic brain injury in serum.

  Analytica chimica acta 20111003

• Redox state and energetic equilibrium determine the magnitude of stress in Hydrilla verticillata upon exposure to arsenate.

  Protoplasma 20111001

• Kinetic characterisation of recombinant Corynebacterium glutamicum NAD+-dependent LDH over-expressed in E. coli and its rescue of an lldD- phenotype in C. glutamicum: the issue of reversibility re-examined.

  Archives of microbiology 20111001

• Mitochondria-localized NAD biosynthesis by nicotinamide mononucleotide adenylyltransferase in Jerusalem artichoke (Helianthus tuberosus L.) heterotrophic tissues.

  Planta 20111001

• The Mycoplasma gallisepticum α-enolase is cell surface-exposed and mediates adherence by binding to chicken plasminogen.

  Microbial pathogenesis 20111001

• Liquid chromatography/time-of-flight mass spectrometry for the analysis of plant samples: a method for simultaneous screening of common cofactors or nucleotides and application to an engineered plant line.

  Plant physiology and biochemistry : PPB 20111001

• Valinomycin induced energy-dependent mitochondrial swelling, cytochrome c release, cytosolic NADH/cytochrome c oxidation and apoptosis.

  Apoptosis : an international journal on programmed cell death 20111001

• Effects of low-level laser therapy on the oxidative metabolism and matrix proteins in the rat masseter muscle.

  Photomedicine and laser surgery 20111001

• The characterization of a unique Trypanosoma brucei β-hydroxybutyrate dehydrogenase.

  Molecular and biochemical parasitology 20111001

• Molecular characterization of the Borrelia burgdorferi in vivo-essential protein PncA.

  Microbiology (Reading, England) 20111001

• The Leishmania nicotinamidase is essential for NAD+ production and parasite proliferation.

  Molecular microbiology 20111001

• Contribution of K99 and D319 to substrate binding and catalysis in the saccharopine dehydrogenase reaction.

  Archives of biochemistry and biophysics 20111001

• SIRT1-mediated acute cardioprotection.

  American journal of physiology. Heart and circulatory physiology 20111001

• Inhibition of mitochondrial respiration by phosphoenolpyruvate.

  Archives of biochemistry and biophysics 20111001

• Acetylcholine promotes the emergence and elongation of lateral roots of Raphanus sativus.

  Plant signaling & behavior 20111001

• Fumarate reductase activity maintains an energized membrane in anaerobic Mycobacterium tuberculosis.

  PLoS pathogens 20111001

• [Effect of overexpression of nicotinic acid phosphoribosyl transferase on succinic acid production in Escherichia coli NZN111].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20111001

• Basis for half-site ligand binding in yeast NAD(+)-specific isocitrate dehydrogenase.

  Biochemistry 20110927

• The oxidation state of active site thiols determines activity of saccharopine dehydrogenase at low pH.

  Archives of biochemistry and biophysics 20110915

• Validation of an LDH assay for assessing nanoparticle toxicity.

  Toxicology 20110905

• Stimulatory effects of calcium on respiration and NAD(P)H synthesis in intact rat heart mitochondria utilizing physiological substrates cannot explain respiratory control in vivo.

  The Journal of biological chemistry 20110902

• A new scheme to calculate isotope effects.

  Journal of molecular modeling 20110901

• Elimination of glycerol and replacement with alternative products in ethanol fermentation by Saccharomyces cerevisiae.

  Journal of industrial microbiology & biotechnology 20110901

• NADPH regulates human NAD kinase, a NADP⁺-biosynthetic enzyme.

  Molecular and cellular biochemistry 20110901

• Lactate dehydrogenase C and energy metabolism in mouse sperm.

  Biology of reproduction 20110901

• Enzymatic characterization of isocitrate dehydrogenase from an emerging zoonotic pathogen Streptococcus suis.

  Biochimie 20110901

• Impact of high pyruvate concentration on kinetics of rabbit muscle lactate dehydrogenase.

  Applied biochemistry and biotechnology 20110901

• Transgenic overexpression of toxin-related ecto-ADP-ribosyltransferase ART2.2 sensitizes T cells but not B cells to NAD-induced cell death.

  Molecular immunology 20110901

• Cyclic ADP-ribose requires CD38 to regulate the release of ATP in visceral smooth muscle.

  The FEBS journal 20110901

• Targeting cancer metabolism: a therapeutic window opens.

  Nature reviews. Drug discovery 20110831

• Structural determinants of discrimination of NAD+ from NADH in yeast mitochondrial NADH kinase Pos5.

  The Journal of biological chemistry 20110826

• One-step, nonenzymatic synthesis of O-acetyl-ADP-ribose and analogues from NAD and carboxylates.

  The Journal of organic chemistry 20110819

• Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.

  Nature 20110817

• Influence of tamoxifen on gluconeogenesis and glycolysis in the perfused rat liver.

  Chemico-biological interactions 20110815

• Crystal structure of UDP-galactose 4-epimerase from the hyperthermophilic archaeon Pyrobaculum calidifontis.

  Archives of biochemistry and biophysics 20110815

• Catalytic mechanism and cofactor preference of dihydrodipicolinate reductase from methicillin-resistant Staphylococcus aureus.

  Archives of biochemistry and biophysics 20110815

• Bio-electrocatalysis of NADH and ethanol based on graphene sheets modified electrodes.

  Talanta 20110815

• FAD-binding site and NADP reactivity in human renalase: a new enzyme involved in blood pressure regulation.

  Journal of molecular biology 20110812

• Structure of the membrane domain of respiratory complex I.

  Nature 20110807

• Caloric restriction primes mitochondria for ischemic stress by deacetylating specific mitochondrial proteins of the electron transport chain.

  Circulation research 20110805

• A ligation-triggered DNAzyme cascade for amplified fluorescence detection of biological small molecules with zero-background signal.

  Journal of the American Chemical Society 20110803

• Brain energy depletion in a rodent model of diffuse traumatic brain injury is not prevented with administration of sodium lactate.

  Brain research 20110802

• Improving ethanol productivity by modification of glycolytic redox factor generation in glycerol-3-phosphate dehydrogenase mutants of an industrial ethanol yeast.

  Journal of industrial microbiology & biotechnology 20110801

• Stimulation of reductive glycerol metabolism by overexpression of an aldehyde dehydrogenase in a recombinant Klebsiella pneumoniae strain defective in the oxidative pathway.

  Journal of industrial microbiology & biotechnology 20110801

• Involvement of PI3K/Akt/CREB and redox changes in mitochondrial defect of osteoblastic MC3T3-E1 cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20110801

• Activation of NAD(P)H:quinone oxidoreductase ameliorates spontaneous hypertension in an animal model via modulation of eNOS activity.

  Cardiovascular research 20110801

• Free [NADH]/[NAD(+)] regulates sirtuin expression.

  Archives of biochemistry and biophysics 20110801

• Pharmacological characterization of purinergic inhibitory neuromuscular transmission in the human colon.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20110801

• Effect of culture conditions on producing and uptake hydrogen flux of biohydrogen fermentation by metabolic flux analysis method.

  Bioresource technology 20110801

• Factors affecting the electrochemical regeneration of NADH by (2,2'-bipyridyl) (pentamethylcyclopentadienyl)-rhodium complexes: impact on their immobilization onto electrode surfaces.

  Bioelectrochemistry (Amsterdam, Netherlands) 20110801

• Discovery of bacterial NAD+-dependent DNA ligase inhibitors: optimization of antibacterial activity.

  Bioorganic & medicinal chemistry letters 20110801

• Glucose sensing by electrogenerated chemiluminescence of glucose-dehydrogenase produced NADH on electrodeposited redox hydrogel.

  Bioelectrochemistry (Amsterdam, Netherlands) 20110801

• Altered behavioral and metabolic circadian rhythms in mice with disrupted NAD+ oscillation.

  Aging 20110801

• Allosteric nucleotide-binding site in the mitochondrial NADH:ubiquinone oxidoreductase (respiratory complex I).

  FEBS letters 20110721

• A ternary mechanism for NADH oxidation by positively charged electron acceptors, catalyzed at the flavin site in respiratory complex I.

  FEBS letters 20110721

• Effect of molecular mobility on coupled enzymatic reactions involving cofactor regeneration using nanoparticle-attached enzymes.

  Journal of biotechnology 20110720

• Rational design and one-step formation of multifunctional gel transducer for simple fabrication of integrated electrochemical biosensors.

  Analytical chemistry 20110715

• Biocatalytic synthesis of gold nanoparticles with cofactor regeneration in recombinant Escherichia coli cells.

  Chemical communications (Cambridge, England) 20110714

• Thermal stabilization of formaldehyde dehydrogenase by encapsulation in liposomes with nicotinamide adenine dinucleotide.

  Enzyme and microbial technology 20110710

• Structure and mechanism of human UDP-glucose 6-dehydrogenase.

  The Journal of biological chemistry 20110708

• Glycolytic oscillations and limits on robust efficiency.

  Science (New York, N.Y.) 20110708

• Catalytic oxidation and determination of β-NADH using self-assembly hybrid of gold nanoparticles and graphene.

  The Analyst 20110707

• Regulation of human mesenchymal stem cell functions by an autocrine loop involving NAD+ release and P2Y11-mediated signaling.

  Stem cells and development 20110701

• Engineering a non-native hydrogen production pathway into Escherichia coli via a cyanobacterial [NiFe] hydrogenase.

  Metabolic engineering 20110701

• Caloric excess or restriction mediated modulation of metabolic enzyme acetylation-proposed effects on cardiac growth and function.

  Biochimica et biophysica acta 20110701

• Improving the ethanol yield by reducing glycerol formation using cofactor regulation in Saccharomyces cerevisiae.

  Biotechnology letters 20110701

• The anoxic plant mitochondrion as a nitrite: NO reductase.

  Mitochondrion 20110701

• Studies on the photosensitized reduction of resorufin and implications for the detection of oxidative stress with Amplex Red.

  Free radical biology & medicine 20110701

• Cloning, sequencing and functional expression of cytosolic malate dehydrogenase from Taenia solium: Purification and characterization of the recombinant enzyme.

  Experimental parasitology 20110701

• Inter-species variation in the oligomeric states of the higher plant Calvin cycle enzymes glyceraldehyde-3-phosphate dehydrogenase and phosphoribulokinase.

  Journal of experimental botany 20110701

• Plasma membrane electron transport in pancreatic β-cells is mediated in part by NQO1.

  American journal of physiology. Endocrinology and metabolism 20110701

• Re-engineering the discrimination between the oxidized coenzymes NAD+ and NADP+ in clostridial glutamate dehydrogenase and a thorough reappraisal of the coenzyme specificity of the wild-type enzyme.

  The FEBS journal 20110701

• Highly efficient synthesis of chiral alcohols with a novel NADH-dependent reductase from Streptomyces coelicolor.

  Bioresource technology 20110701

• Inhibitory effect of organic carbon on CO₂ fixing by non-photosynthetic microbial community isolated from the ocean.

  Bioresource technology 20110701

• Fluorescence lifetime imaging unravels C. trachomatis metabolism and its crosstalk with the host cell.

  PLoS pathogens 20110701

• Oxidative stress and reduced glutamine synthetase activity in the absence of inflammation in the cortex of mice with experimental allergic encephalomyelitis.

  Neuroscience 20110630

• Methylmalonate-semialdehyde dehydrogenase from Bacillus subtilis: substrate specificity and coenzyme A binding.

  The Journal of biological chemistry 20110624

• Linking distinct conformations of nicotinamide adenine dinucleotide with protein fold/function.

  The journal of physical chemistry. B 20110623

• Proton-induced dynamic equilibrium between cyclometalated ruthenium rNHC (remote N-heterocyclic carbene) tautomers with an NAD+/NADH function.

  Inorganic chemistry 20110620

• Pathways and subcellular compartmentation of NAD biosynthesis in human cells: from entry of extracellular precursors to mitochondrial NAD generation.

  The Journal of biological chemistry 20110617

• Optically measured NADH concentrations are unaffected by propofol induced EEG silence during transient cerebral hypoperfusion in anesthetized rabbits.

  Brain research 20110617

• Conformational heterogeneity within the Michaelis complex of lactate dehydrogenase.

  The journal of physical chemistry. B 20110616

• Synthesis and biological activity of splitomicin analogs targeted at human NAD(+)-dependent histone deacetylases (sirtuins).

  Bioorganic & medicinal chemistry 20110615

• The anti-cancer agent guttiferone-A permeabilizes mitochondrial membrane: ensuing energetic and oxidative stress implications.

  Toxicology and applied pharmacology 20110615

• NAD+-metabolizing ecto-enzymes shape tumor-host interactions: the chronic lymphocytic leukemia model.

  FEBS letters 20110606

• Disruption of pyridine nucleotide redox status during oxidative challenge at normal and low-glucose states: implications for cellular adenosine triphosphate, mitochondrial respiratory activity, and reducing capacity in colon epithelial cells.

  Antioxidants & redox signaling 20110601

• The kinetic properties of the glutamate dehydrogenase of Teladorsagia circumcincta and their significance for the lifestyle of the parasite.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20110601

• A highly efficient ADH-coupled NADH-recycling system for the asymmetric bioreduction of carbon-carbon double bonds using enoate reductases.

  Biotechnology and bioengineering 20110601

• A novel L-aspartate dehydrogenase from the mesophilic bacterium Pseudomonas aeruginosa PAO1: molecular characterization and application for L-aspartate production.

  Applied microbiology and biotechnology 20110601

• Endogenous protein mono-ADP-ribosylation in Arabidopsis thaliana.

  Planta 20110601

• Beta-amyloid activates PARP causing astrocytic metabolic failure and neuronal death.

  Brain : a journal of neurology 20110601

• Reduced nicotinamide adenine dinucleotide fluorescence lifetime detected poly(adenosine-5'-diphosphate-ribose) polymerase-1-mediated cell death and therapeutic effect of pyruvate.

  Journal of biomedical optics 20110601

• 4-Pyridone-3-carboxamide-1-β-D-ribonucleoside triphosphate (4PyTP), a novel NAD metabolite accumulating in erythrocytes of uremic children: a biomarker for a toxic NAD analogue in other tissues?

  Toxins 20110601

• Murine hepatic aldehyde dehydrogenase 1a1 is a major contributor to oxidation of aldehydes formed by lipid peroxidation.

  Chemico-biological interactions 20110530

• Metabolic mechanisms of methanol/formaldehyde in isolated rat hepatocytes: carbonyl-metabolizing enzymes versus oxidative stress.

  Chemico-biological interactions 20110530

• NADH fluorescence lifetime analysis of the effect of magnesium ions on ALDH2.

  Chemico-biological interactions 20110530

• Inactivation of porcine kidney betaine aldehyde dehydrogenase by hydrogen peroxide.

  Chemico-biological interactions 20110530

• Protective effects of synthetic kynurenines on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice.

  Brain research bulletin 20110530

• Two-step synthesis of novel, bioactive derivatives of the ubiquitous cofactor nicotinamide adenine dinucleotide (NAD).

  Journal of medicinal chemistry 20110526

• Progress in the function and regulation of ADP-Ribosylation.

  Science signaling 20110524

• Anti-virulence strategy against Brucella suis: synthesis, biological evaluation and molecular modeling of selective histidinol dehydrogenase inhibitors.

  Organic & biomolecular chemistry 20110521

• On the nonspecific degradation of NAD+ to nicotinamide riboside.

  The Journal of biological chemistry 20110520

• Binding ligands and cofactor to L-lactate dehydrogenase from human skeletal and heart muscles.

  The journal of physical chemistry. B 20110519

• 4-Hydroxynonenal inhibits SIRT3 via thiol-specific modification.

  Chemical research in toxicology 20110516

• An LC-MS-based chemical and analytical method for targeted metabolite quantification in the model cyanobacterium Synechococcus sp. PCC 7002.

  Analytical chemistry 20110515

• Signal transducers and enzyme cofactors are susceptible to oxidation by nanographite impurities in carbon nanotube materials.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20110509

• The glucose/xylose facilitator Gxf1 from Candida intermedia expressed in a xylose-fermenting industrial strain of Saccharomyces cerevisiae increases xylose uptake in SSCF of wheat straw.

  Enzyme and microbial technology 20110506

• The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon.

  Cell metabolism 20110504

• Functional model of metabolite gating by human voltage-dependent anion channel 2.

  Biochemistry 20110503

• Strategies for efficient repetitive production of succinate using metabolically engineered Escherichia coli.

  Bioprocess and biosystems engineering 20110501

• An enzymatic fluorescent assay for the quantification of phosphite in a microtiter plate format.

  Analytical biochemistry 20110501

• Alteration of reducing powers in an isogenic phosphoglucose isomerase (pgi)-disrupted Escherichia coli expressing NAD(P)-dependent malic enzymes and NADP-dependent glyceraldehyde 3-phosphate dehydrogenase.

  Letters in applied microbiology 20110501

• Ethanol exposure modulates hepatic S-adenosylmethionine and S-adenosylhomocysteine levels in the isolated perfused rat liver through changes in the redox state of the NADH/NAD(+) system.

  Biochimica et biophysica acta 20110501

• Fluorescent and colorimetric chemosensors for detection of nucleotides, FAD and NADH: highlighted research during 2004-2010.

  Chemical Society reviews 20110501

• Atomic level description of the domain closure in a dimeric enzyme: thermus thermophilus 3-isopropylmalate dehydrogenase.

  Molecular bioSystems 20110501

• Biochemical characterization of glyceraldehyde-3-phosphate dehydrogenase from Thermococcus kodakarensis KOD1.

  Extremophiles : life under extreme conditions 20110501

• Responsive interface switchable by logically processed physiological signals: toward 'smart' actuators for signal amplification and drug delivery.

  ACS applied materials & interfaces 20110501

• Structural and biochemical characterization of NarE, an iron-containing ADP-ribosyltransferase from Neisseria meningitidis.

  The Journal of biological chemistry 20110429

• Rational design and engineering of quantum-dot-sensitized TiO₂ nanotube arrays for artificial photosynthesis.

  Advanced materials (Deerfield Beach, Fla.) 20110426

• Phosphate-responsive signaling pathway is a novel component of NAD+ metabolism in Saccharomyces cerevisiae.

  The Journal of biological chemistry 20110422

• Structure and biochemical functions of SIRT6.

  The Journal of biological chemistry 20110422

• A novel microassay for measuring blood alcohol concentration using a disposable biosensor strip.

  Forensic science international 20110415

• The application of novel spindle-like polypyrrole hollow nanocapsules containing Pt nanoparticles in electrocatalysis oxidation of nicotinamide adenine dinucleotide (NADH).

  Journal of colloid and interface science 20110415

• Development of amperometric α-ketoglutarate biosensor based on ruthenium-rhodium modified carbon fiber enzyme microelectrode.

  Biosensors & bioelectronics 20110415

• Optical analysis of lactate dehydrogenase and glucose by CdTe quantum dots and their dual simultaneous detection.

  Biosensors & bioelectronics 20110415

• A hyaluronic acid dispersed carbon nanotube electrode used for a mediatorless NADH sensing and biosensing.

  Talanta 20110415

• Development of a sensitive long-wavelength fluorogenic probe for nitroreductase: a new fluorimetric indictor for analyte determination by dehydrogenase-coupled biosensors.

  Biosensors & bioelectronics 20110415

• Focal cerebral ischemia and mitochondrial dysfunction in the TNFα-transgenic rat.

  Brain research 20110412

• Activation of cell death mediated by apoptosis-inducing factor due to the absence of poly(ADP-ribose) glycohydrolase.

  Biochemistry 20110412

• Review: NAD +: a modulator of immune functions.

  Innate immunity 20110401

• Renalase deficiency aggravates ischemic myocardial damage.

  Kidney international 20110401

• A gold nanoparticle-mediated enzyme bioreactor for inhibitor screening by capillary electrophoresis.

  Analytical biochemistry 20110401

• Increased drying rate lowers the critical water content for survival in embryonic axes of English oak (Quercus robur L.) seeds.

  Journal of integrative plant biology 20110401

• Lidocaine depolarizes the mitochondrial membrane potential by intracellular alkalization in rat dorsal root ganglion neurons.

  Journal of anesthesia 20110401

• Structures of iron-dependent alcohol dehydrogenase 2 from Zymomonas mobilis ZM4 with and without NAD+ cofactor.

  Journal of molecular biology 20110401

• Studies on the mechanism of ring hydrolysis in phenylacetate degradation: a metabolic branching point.

  The Journal of biological chemistry 20110401

• Mitochondrial energy metabolism in young bamboo rhizomes from Bambusa oldhamii and Phyllostachys edulis during shooting stage.

  Plant physiology and biochemistry : PPB 20110401

• Monooxygenation by a thermophilic cytochrome P450 via direct electron donation from NADH.

  Metallomics : integrated biometal science 20110401

• Native fluorescence spectroscopic evaluation of chemotherapeutic effects on malignant cells using nonnegative matrix factorization analysis.

  Technology in cancer research & treatment 20110401

• Diagnostic potential of Stokes Shift spectroscopy of breast and prostate tissues-- a preliminary pilot study.

  Technology in cancer research & treatment 20110401

• A bioassay for the detection of perchlorate in the ppb range.

  Environmental science & technology 20110401

• Molecular beacon based bioassay for highly sensitive and selective detection of nicotinamide adenine dinucleotide and the activity of alanine aminotransferase.

  Analytical chemistry 20110401

• Physiological importance of cytochrome c peroxidase in ethanologenic thermotolerant Zymomonas mobilis.

  Journal of molecular microbiology and biotechnology 20110401

• Biohydrogenation from biomass sugar mediated by in vitro synthetic enzymatic pathways.

  Chemistry & biology 20110325

• Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.

  Journal of medicinal chemistry 20110324

• Xanthine dehydrogenase electrocatalysis: autocatalysis and novel activity.

  The journal of physical chemistry. B 20110324

• Multiple roles of component proteins in bacterial multicomponent monooxygenases: phenol hydroxylase and toluene/o-xylene monooxygenase from Pseudomonas sp. OX1.

  Biochemistry 20110322

• Reaction mechanism of single subunit NADH-ubiquinone oxidoreductase (Ndi1) from Saccharomyces cerevisiae: evidence for a ternary complex mechanism.

  The Journal of biological chemistry 20110318

• NAD+-dependent SIRT1 deacetylase participates in epigenetic reprogramming during endotoxin tolerance.

  The Journal of biological chemistry 20110318

• Engineering the nucleotide coenzyme specificity and sulfhydryl redox sensitivity of two stress-responsive aldehyde dehydrogenase isoenzymes of Arabidopsis thaliana.

  The Biochemical journal 20110315

• Disruption of adaptive energy metabolism and elevated ribosomal p-S6K1 levels contribute to INCL pathogenesis: partial rescue by resveratrol.

  Human molecular genetics 20110315

• Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair.

  Cancer research 20110315

• Study of the thiol/disulfide redox systems of the anaerobe Desulfovibrio vulgaris points out pyruvate:ferredoxin oxidoreductase as a new target for thioredoxin 1.

  The Journal of biological chemistry 20110311

• Redox cycling amplified electrochemical detection of DNA hybridization: application to pathogen E. coli bacterial RNA.

  Analytica chimica acta 20110309

• Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model.

  The Journal of cell biology 20110307

• The general anesthetic sevoflurane affects the expression of clock gene mPer2 accompanying the change of NAD+ level in the suprachiasmatic nucleus of mice.

  Neuroscience letters 20110303

• Flavocytochrome P450 BM3 mutant W1046A is a NADH-dependent fatty acid hydroxylase: implications for the mechanism of electron transfer in the P450 BM3 dimer.

  Archives of biochemistry and biophysics 20110301

• A novel L-isoleucine metabolism in Bacillus thuringiensis generating (2S,3R,4S)-4-hydroxyisoleucine, a potential insulinotropic and anti-obesity amino acid.

  Applied microbiology and biotechnology 20110301

• TRPM2 cation channels, oxidative stress and neurological diseases: where are we now?

  Neurochemical research 20110301

• Metabolic networks to combat oxidative stress in Pseudomonas fluorescens.

  Antonie van Leeuwenhoek 20110301

• The mechanism for regulating ethanol fermentation by redox levels in Thermoanaerobacter ethanolicus.

  Metabolic engineering 20110301

• Fructose induces gluconeogenesis and lipogenesis through a SIRT1-dependent mechanism.

  The Journal of endocrinology 20110301

• The functions of an apple cytosolic malate dehydrogenase gene in growth and tolerance to cold and salt stresses.

  Plant physiology and biochemistry : PPB 20110301

• Catalytic properties of the retinal rod outer segment disk ADP-ribosyl cyclase.

  Visual neuroscience 20110301

• Degradation of pentachlorophenol by a novel peroxidase-catalyzed process in the presence of reduced nicotinamide adenine dinucleotide.

  Chemosphere 20110301

• Increase of reduced nicotinamide adenine dinucleotide fluorescence lifetime precedes mitochondrial dysfunction in staurosporine-induced apoptosis of HeLa cells.

  Journal of biomedical optics 20110301

• Mechanism of cardioprotective effect of adenocine and non-glycoside cardiotonic drugs during experimental chronic cardiac insufficiency.

  Bulletin of experimental biology and medicine 20110301

• Size- and shape-dependent activity of metal nanoparticles as hydrogen-evolution catalysts: mechanistic insights into photocatalytic hydrogen evolution.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20110225

• How does pressure affect barrier compression and isotope effects in an enzymatic hydrogen tunneling reaction?

  Angewandte Chemie (International ed. in English) 20110225

• SIRT3 substrate specificity determined by peptide arrays and machine learning.

  ACS chemical biology 20110218

• Binding of glyceraldehyde-3-phosphate dehydrogenase to the cis-acting element of structure-anchored repression in ccn2 mRNA.

  Biochemical and biophysical research communications 20110218

• Electron- and hydride-transfer reactivity of an isolable manganese(V)-oxo complex.

  Journal of the American Chemical Society 20110216

• Lysine deacetylation in ischaemic preconditioning: the role of SIRT1.

  Cardiovascular research 20110215

• Growth of M. avium subspecies paratuberculosis in culture is enhanced by nicotinic acid, nicotinamide, and α and β nicotinamide adenine dinucleotide.

  Digestive diseases and sciences 20110201

• Determination of formal potential of NADH/NAD+ redox couple and catalytic oxidation of NADH using poly(phenosafranin)-modified carbon electrodes.

  Bioelectrochemistry (Amsterdam, Netherlands) 20110201

• Simultaneous monitoring of tissue PO2 and NADH fluorescence during synaptic stimulation and spreading depression reveals a transient dissociation between oxygen utilization and mitochondrial redox state in rat hippocampal slices.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110201

• Enzymatic synthesis of L-lactic acid from carbon dioxide and ethanol with an inherent cofactor regeneration cycle.

  Biotechnology and bioengineering 20110201

• β-nicotinamide adenine dinucleotide is an enteric inhibitory neurotransmitter in human and nonhuman primate colons.

  Gastroenterology 20110201

• Identification and characterization of the propanediol utilization protein PduP of Lactobacillus reuteri for 3-hydroxypropionic acid production from glycerol.

  Applied microbiology and biotechnology 20110201

• Visible wavelength spectrophotometric assays of L-aspartate and D-aspartate using hyperthermophilic enzyme systems.

  Analytical biochemistry 20110201

• Robust protective effects of a novel multimodal neuroprotectant oxopropanoyloxy benzoic acid (a salicylic acid/pyruvate ester) in the postischemic brain.

  Molecular pharmacology 20110201

• Biotechnological production of mannitol and its applications.

  Applied microbiology and biotechnology 20110201

• Characterization of lactate dehydrogenase enzyme in seminal plasma of Japanese quail (Coturnix coturnix japonica).

  Theriogenology 20110201

• Multiple pathways regulating the calorie restriction response in yeast.

  The journals of gerontology. Series A, Biological sciences and medical sciences 20110201

• Regulation of malignant phenotype and bioenergetics by a π-electron donor-inducible mitochondrial MgATPase.

  International journal of molecular medicine 20110201

• In vivo hyperoxic preconditioning protects against rat-heart ischemia/reperfusion injury by inhibiting mitochondrial permeability transition pore opening and cytochrome c release.

  Free radical biology & medicine 20110201

• Oxygen radicals shaping evolution: why fatty acid catabolism leads to peroxisomes while neurons do without it: FADH₂/NADH flux ratios determining mitochondrial radical formation were crucial for the eukaryotic invention of peroxisomes and catabolic tissue differentiation.

  BioEssays : news and reviews in molecular, cellular and developmental biology 20110201

• A functional role for the 'fibroblast-like cells' in gastrointestinal smooth muscles.

  The Journal of physiology 20110201

• Crystallization and preliminary X-ray crystallographic studies of enoyl-acyl carrier protein reductase (FabI) from Psuedomonas aeruginosa.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20110201

• Reduced mitochondrial function in obesity-associated fatty liver: SIRT3 takes on the fat.

  Aging 20110201

• Dynamic conformations of the CD38-mediated NAD cyclization captured in a single crystal.

  Journal of molecular biology 20110128

• Electrochemical biosensors based on redox carbon nanotubes prepared by noncovalent functionalization with 1,10-phenanthroline-5,6-dione.

  The Analyst 20110121

• Molecular identification of the enzyme responsible for the mitochondrial NADH-supported ammonium-dependent hydrogen peroxide production.

  FEBS letters 20110121

• Characterization of an NADH-dependent persulfide reductase from Shewanella loihica PV-4: implications for the mechanism of sulfur respiration via FAD-dependent enzymes.

  Biochemistry 20110118

• SiO2/SnO2/Sb2O5 microporous ceramic material for immobilization of Meldola's blue: application as an electrochemical sensor for NADH.

  Biosensors & bioelectronics 20110115

• Muscle type-specific responses to NAD+ salvage biosynthesis promote muscle function in Caenorhabditis elegans.

  Developmental biology 20110115

• Toluidine blue adsorbed on alcohol dehydrogenase modified glassy carbon electrode for voltammetric determination of ethanol.

  Talanta 20110115

• Electrochemical detection of nicotinamide adenine dinucleotide based on molecular beacon-like DNA and E. coli DNA ligase.

  Talanta 20110115

• Circular dichroism spectroscopy is a sensitive tool for investigation of bilirubin-enzyme interactions.

  Biomacromolecules 20110110

• Targeting glycolysis: a fragment based approach towards bifunctional inhibitors of hLDH-5.

  Chemical communications (Cambridge, England) 20110107

• Immobilization of phenylalanine dehydrogenase and its application in flow-injection analysis system for determination of plasma phenylalanine.

  Applied biochemistry and biotechnology 20110101

• The specificity of proton-translocating transhydrogenase for nicotinamide nucleotides.

  Biochimica et biophysica acta 20110101

• Role of Ca(2+) in structure and function of Complex I from Escherichia coli.

  Biochimica et biophysica acta 20110101

• Biosynthesis of UDP-xylose and UDP-arabinose in Sinorhizobium meliloti 1021: first characterization of a bacterial UDP-xylose synthase, and UDP-xylose 4-epimerase.

  Microbiology (Reading, England) 20110101

• Nanoporous silica glass for the immobilization of interactive enzyme systems.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Growth- and substrate-dependent transcription of formate dehydrogenase and hydrogenase coding genes in Syntrophobacter fumaroxidans and Methanospirillum hungatei.

  Microbiology (Reading, England) 20110101

• Purification and characterization of a novel NADH-dependent carbonyl reductase from Pichia stipitis involved in biosynthesis of optically pure ethyl (S)-4-chloro-3-hydroxybutanoate.

  Bioresource technology 20110101

• Prooxidant activity of fisetin: effects on energy metabolism in the rat liver.

  Journal of biochemical and molecular toxicology 20110101

• An analytical model of non-photorespiratory CO₂release in the light and dark in leaves of C₃species based on stoichiometric flux balance.

  Plant, cell & environment 20110101

• Probing the redox metabolism in the strictly anaerobic, extremely thermophilic, hydrogen-producing Caldicellulosiruptor saccharolyticus using amperometry.

  Extremophiles : life under extreme conditions 20110101

• Ethanol metabolism by HeLa cells transduced with human alcohol dehydrogenase isoenzymes: control of the pathway by acetaldehyde concentration.

  Alcoholism, clinical and experimental research 20110101

• NAD+ treatment decreases tumor cell survival by inducing oxidative stress.

  Frontiers in bioscience (Elite edition) 20110101

• Crystallization and preliminary X-ray crystallographic analysis of human quinolinate phosphoribosyltransferase.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20110101

• Alpha-synuclein is a cellular ferrireductase.

  PloS one 20110101

• [Changes of redox processes in liver under pv-88 at experimental hemorrhagic shock].

  Georgian medical news 20110101

• Neuronal Sirt3 protects against excitotoxic injury in mouse cortical neuron culture.

  PloS one 20110101

• Effects of 1-methylnicotinamide and its metabolite N-methyl-2-pyridone-5-carboxamide on streptozotocin-induced toxicity in murine insulinoma MIN6 cell line.

  Acta biochimica Polonica 20110101

• WWOX oxidoreductase--substrate and enzymatic characterization.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20110101

• NQO1-dependent redox cycling of idebenone: effects on cellular redox potential and energy levels.

  PloS one 20110101

• Kinetic resolution of 3-fluoroalanine using a fusion protein of D-amino acid oxidase with Vitroscilla hemoglobin.

  Bioscience, biotechnology, and biochemistry 20110101

• NMNAT expression and its relation to NAD metabolism.

  Current medicinal chemistry 20110101

• NAMPT in regulated NAD biosynthesis and its pivotal role in human metabolism.

  Current medicinal chemistry 20110101

• Rehab of NAD(P)-dependent enzymes with NAD(P)-based inhibitors.

  Current medicinal chemistry 20110101

• Efficient conversion of phenylpyruvic acid to phenyllactic acid by using whole cells of Bacillus coagulans SDM.

  PloS one 20110101

• Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats.

  PloS one 20110101

• Nrt1 and Tna1-independent export of NAD+ precursor vitamins promotes NAD+ homeostasis and allows engineering of vitamin production.

  PloS one 20110101

• Genomic characterization of Haemophilus parasuis SH0165, a highly virulent strain of serovar 5 prevalent in China.

  PloS one 20110101

• Purification and characterization of an NADH-dependent alcohol dehydrogenase from Candida maris for the synthesis of optically active 1-(pyridyl)ethanol derivatives.

  Bioscience, biotechnology, and biochemistry 20110101

• NAD blocks high glucose induced mesangial hypertrophy via activation of the sirtuins-AMPK-mTOR pathway.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101

• Amyloid-β-induced mitochondrial dysfunction impairs the autophagic lysosomal pathway in a tubulin dependent pathway.

  Journal of Alzheimer's disease : JAD 20110101

• Adenosine thiamine triphosphate (AThTP) inhibits poly(ADP-ribose) polymerase-1 (PARP-1) activity.

  Journal of nutritional science and vitaminology 20110101

• Effects of acupuncture at Taixi acupoint (KI3) on kidney proteome.

  The American journal of Chinese medicine 20110101

• Wld(S) reduces paraquat-induced cytotoxicity via SIRT1 in non-neuronal cells by attenuating the depletion of NAD.

  PloS one 20110101

• Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells.

  PloS one 20110101

• A non-NadB type L-aspartate dehydrogenase from Ralstonia eutropha strain JMP134: molecular characterization and physiological functions.

  Bioscience, biotechnology, and biochemistry 20110101

• [Catabolic Activities Of Formaldehyde Enzymes In Recombinant Strains Of Hansenula Polymorpha].

  Mikrobiologiia 20110101

• Synthesis of methylenebis(phosphonate) analogues of 2-, 4-, and 6-pyridones of nicotinamide adenine dinucleotide.

  Nucleosides, nucleotides & nucleic acids 20110101

• Characterization of two isozymes of coniferyl alcohol dehydrogenase from Streptomyces sp. NL15-2K.

  Bioscience, biotechnology, and biochemistry 20110101

• Modulation of FAD-dependent monooxygenase activity from aromatic compounds-degrading Stenotrophomonas maltophilia strain KB2.

  Acta biochimica Polonica 20110101

• Automated biochemical, morphological, and organizational assessment of precancerous changes from endogenous two-photon fluorescence images.

  PloS one 20110101

• [Anaerobic synthesis of succinic acid by Escherichia coli strains with activated NAD+ reducing pyruvate dehydrogenase complex].

  Prikladnaia biokhimiia i mikrobiologiia 20110101

• In silico characterization of microbial electrosynthesis for metabolic engineering of biochemicals.

  Microbial cell factories 20110101

• Structural basis of cooperativity in human UDP-glucose dehydrogenase.

  PloS one 20110101

• Catalytic properties of the isolated diaphorase fragment of the NAD-reducing [NiFe]-hydrogenase from Ralstonia eutropha.

  PloS one 20110101

• Mitochondrial NAD+-dependent malic enzyme from Anopheles stephensi: a possible novel target for malaria mosquito control.

  Malaria journal 20110101

• Interaction of reduced nicotinamide adenine dinucleotide with an antifreeze protein from Dendroides canadensis: mechanistic implication of antifreeze activity enhancement.

  Journal of molecular recognition : JMR 20110101

• Determination of the crystal structure and active residues of FabV, the enoyl-ACP reductase from Xanthomonas oryzae.

  PloS one 20110101

• Electropolymerized poly(Toluidine blue)-modified carbon felt for highly sensitive amperometric determination of NADH in flow injection analysis.

  Journal of environmental sciences (China) 20110101

• Genome-scale consequences of cofactor balancing in engineered pentose utilization pathways in Saccharomyces cerevisiae.

  PloS one 20110101

• SIRT3 regulates mitochondrial protein acetylation and intermediary metabolism.

  Cold Spring Harbor symposia on quantitative biology 20110101

• Determination of ammonium ion using a reagentless amperometric biosensor based on immobilized alanine dehydrogenase.

  Sensors (Basel, Switzerland) 20110101

• Effects of Al(III) and nano-Al13 species on malate dehydrogenase activity.

  Sensors (Basel, Switzerland) 20110101

• Proteomic analysis of endothelial cold-adaptation.

  BMC genomics 20110101

• Adult body weight is programmed by a redox-regulated and energy-dependent process during the pronuclear stage in mouse.

  PloS one 20110101

• Congenital myopathies: clinical and immunohistochemical study.

  Neurology India 20110101

• [UDCA in the treatment of nonalcoholic fatty liver disease].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20110101

• Redox-dependent Brca1 transcriptional regulation by an NADH-sensor CtBP1.

  Oncogene 20101216

• Characterization of azido-NAD+ to assess its potential as a two-dimensional infrared probe of enzyme dynamics.

  Analytical biochemistry 20101215

• Ceramide-induced activation of cytosolic NADH/cytochrome c electron transport pathway: An additional source of energy for apoptosis.

  Archives of biochemistry and biophysics 20101215

• Identification of the aryl hydrocarbon receptor target gene TiPARP as a mediator of suppression of hepatic gluconeogenesis by 2,3,7,8-tetrachlorodibenzo-p-dioxin and of nicotinamide as a corrective agent for this effect.

  The Journal of biological chemistry 20101210

• Mitochondrial NADH kinase, Pos5p, is required for efficient iron-sulfur cluster biogenesis in Saccharomyces cerevisiae.

  The Journal of biological chemistry 20101210

• Genomics-driven reconstruction of acinetobacter NAD metabolism: insights for antibacterial target selection.

  The Journal of biological chemistry 20101210

• New insights into the superoxide generation sites in bovine heart NADH-ubiquinone oxidoreductase (Complex I): the significance of protein-associated ubiquinone and the dynamic shifting of generation sites between semiflavin and semiquinone radicals.

  Biochimica et biophysica acta 20101201

• Possible roles of two quinone molecules in direct and indirect proton pumps of bovine heart NADH-quinone oxidoreductase (complex I).

  Biochimica et biophysica acta 20101201

• Effects of ranolazine on fatty acid transformation in the isolated perfused rat liver.

  Molecular and cellular biochemistry 20101201

• Prenatal flutamide enhances survival in a myogenic mouse model of spinal bulbar muscular atrophy.

  Neuro-degenerative diseases 20101201

• Structure elucidation of the thermal degradation products of the nucleotide cofactors NADH and NADPH by nano-ESI-FTICR-MS and HPLC-MS.

  Analytical and bioanalytical chemistry 20101201

• Structural investigation of myo-inositol dehydrogenase from Bacillus subtilis: implications for catalytic mechanism and inositol dehydrogenase subfamily classification.

  The Biochemical journal 20101201

• Sulforaphane modulates the expression of Cyp6a2 and Cyp6g1 in larvae of the ST and HB crosses of the Drosophila wing spot test and is genotoxic in the ST cross.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20101201

• Global gene expression analysis of Aspergillus nidulans reveals metabolic shift and transcription suppression under hypoxia.

  Molecular genetics and genomics : MGG 20101201

• Spin labeling of the Escherichia coli NADH ubiquinone oxidoreductase (complex I).

  Biochimica et biophysica acta 20101201

• L-lactate metabolism can occur in normal and cancer prostate cells via the novel mitochondrial L-lactate dehydrogenase.

  International journal of oncology 20101201

• Online electrochemical measurements of Ca2+ and Mg2+ in rat brain based on divalent cation enhancement toward electrocatalytic NADH oxidation.

  Analytical chemistry 20101201

• Identification and characterization of a pantothenate kinase (PanK-sp) from streptomyces peucetius ATCC 27952.

  Journal of microbiology and biotechnology 20101201

• Factors controlling the mechanism of NAD(+) non-redox reactions.

  Journal of the American Chemical Society 20101124

• Manganese(V)-oxo corroles in hydride-transfer reactions.

  Chemical communications (Cambridge, England) 20101121

• The aging-associated enzyme CLK-1 is a member of the carboxylate-bridged diiron family of proteins.

  Biochemistry 20101116

• A liposome-based energy conversion system for accelerating the multi-enzyme reactions.

  Physical chemistry chemical physics : PCCP 20101114

• Reduction kinetics of a flavin oxidoreductase LuxG from Photobacterium leiognathi (TH1): half-sites reactivity.

  Biochemistry 20101102

• NAD(+) -dependent histone deacetylases (sirtuins) as novel therapeutic targets.

  Medicinal research reviews 20101101

• Role of mitochondrial dysfunction in cardiac glycoside toxicity.

  Journal of molecular and cellular cardiology 20101101

• Contribution of P2X7 receptors to adenosine uptake by cultured mouse astrocytes.

  Glia 20101101

• Electrochemical and spectral study on the effects of Al(III) and nano-Al13 species on glutamate dehydrogenase activity.

  Colloids and surfaces. B, Biointerfaces 20101101

• Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells.

  Experimental hematology 20101101

• The simultaneous determination of NAD(H) and NADP(H) utilization by glutamate dehydrogenase.

  Molecular and cellular biochemistry 20101101

• Chromate reductase activity of the Paracoccus denitrificans ferric reductase B (FerB) protein and its physiological relevance.

  Archives of microbiology 20101101

• An integrated analysis of enzyme activities, cofactor pools and metabolic fluxes in baculovirus-infected Spodoptera frugiperda Sf9 cells.

  Journal of biotechnology 20101101

• Inhibition of the kynurenine-NAD+ pathway leads to energy failure and exacerbates apoptosis in pneumococcal meningitis.

  Journal of neuropathology and experimental neurology 20101101

• Metabolic stress-induced programmed cell death in Xanthomonas.

  FEMS microbiology letters 20101101

• Structure of the Francisella tularensis enoyl-acyl carrier protein reductase (FabI) in complex with NAD(+) and triclosan.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20101101

• [The production of hydroxyl radical in HRP-NADH-H2O/O2 systems and its application in chlorobenzene removal].

  Guang pu xue yu guang pu fen xi = Guang pu 20101101

• Inhibition of nicotinamide phosphoribosyltransferase: cellular bioenergetics reveals a mitochondrial insensitive NAD pool.

  The Journal of biological chemistry 20101029

• Determinants of substrate binding and protonation in the flavoenzyme xenobiotic reductase A.

  Journal of molecular biology 20101022

• Characterization of a broad-range aldehyde dehydrogenase involved in alkane degradation in Geobacillus thermodenitrificans NG80-2.

  Microbiological research 20101020

• Reactive oxygen species originating from mitochondria regulate the cardiac sodium channel.

  Circulation research 20101015

• Biochemical mechanism of caffeic acid phenylethyl ester (CAPE) selective toxicity towards melanoma cell lines.

  Chemico-biological interactions 20101006

• Do dynamic effects play a significant role in enzymatic catalysis? A theoretical analysis of formate dehydrogenase.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20101004

• Reverse genetics approach to characterize a function of NADH-glutamate synthase1 in rice plants.

  Amino acids 20101001

• Effects of glucose and insulin on HepG2-C3A cell metabolism.

  Biotechnology and bioengineering 20101001

• Inhibition of glycolysis in the retina by oxidative stress: prevention by pyruvate.

  Molecular and cellular biochemistry 20101001

• Ex vivo supplementation with nicotinic acid enhances cellular poly(ADP-ribosyl)ation and improves cell viability in human peripheral blood mononuclear cells.

  Biochemical pharmacology 20101001

• Pharmacological inhibitors of NAD(P)H quinone oxidoreductase, NQO1: structure/activity relationships and functional activity in tumour cells.

  Biochemical pharmacology 20101001

• Aldehyde dehydrogenase 1B1: molecular cloning and characterization of a novel mitochondrial acetaldehyde-metabolizing enzyme.

  Drug metabolism and disposition: the biological fate of chemicals 20101001

• Triggering the redox reaction of cytochrome c on a biomimetic layer and elimination of interferences for NADH detection.

  Biomaterials 20101001

• The hidden life of NAD+-consuming ectoenzymes in the endocrine system.

  Journal of molecular endocrinology 20101001

• Development of isoniazid-NAD truncated adducts embedding a lipophilic fragment as potential bi-substrate InhA inhibitors and antimycobacterial agents.

  European journal of medicinal chemistry 20101001

• The biphasic NAD(P)H fluorescence response of astrocytes to dopamine reflects the metabolic actions of oxidative phosphorylation and glycolysis.

  Journal of neurochemistry 20101001

• Control of endothelial sprouting by a Tel-CtBP complex.

  Nature cell biology 20101001

• Essential role of copper in the activity and regular periodicity of a recombinant, tumor-associated, cell surface, growth-related and time-keeping hydroquinone (NADH) oxidase with protein disulfide-thiol interchange activity (ENOX2).

  Journal of bioenergetics and biomembranes 20101001

• Pervasive cryptic epistasis in molecular evolution.

  PLoS genetics 20101001

• Characterization of Deinococcus radiophilus thioredoxin reductase active with both NADH and NADPH.

  Journal of microbiology (Seoul, Korea) 20101001

• Paracoccus denitrificans proton-translocating ATPase: kinetics of oxidative phosphorylation.

  Biochemistry. Biokhimiia 20101001

• Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 3. Role of lysyl and tyrosyl residues of the C-terminal extension.

  Biochemistry 20100928

• Characterizing the origin of autofluorescence in human esophageal epithelium under ultraviolet excitation.

  Optics express 20100927

• NADH oxidase activity of Bacillus subtilis nitroreductase NfrA1: insight into its biological role.

  FEBS letters 20100924

• Kinetic analysis of 14-3-3-inhibited Arabidopsis thaliana nitrate reductase.

  Biochemistry 20100921

• Enzyme biosensor based on NAD-sensitive quantum dots.

  Biosensors & bioelectronics 20100915

• Structural and functional studies of WlbA: A dehydrogenase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid .

  Biochemistry 20100914

• Structure and engineering of L-arabinitol 4-dehydrogenase from Neurospora crassa.

  Journal of molecular biology 20100910

• Transition state of ADP-ribosylation of acetyllysine catalyzed by Archaeoglobus fulgidus Sir2 determined by kinetic isotope effects and computational approaches.

  Journal of the American Chemical Society 20100908

• Flavohemoglobin and nitric oxide detoxification in the human protozoan parasite Giardia intestinalis.

  Biochemical and biophysical research communications 20100903

• Redox mechanism of glycosidic bond hydrolysis catalyzed by 6-phospho-alpha-glucosidase: a DFT study.

  The journal of physical chemistry. B 20100902

• Expression and purification of untagged and histidine-tagged folate-dependent tRNA:m5U54 methyltransferase from Bacillus subtilis.

  Protein expression and purification 20100901

• Regulation of SIRT1 in cellular functions: role of polyphenols.

  Archives of biochemistry and biophysics 20100901

• Role of CD38, a cyclic ADP-ribosylcyclase, in morphine antinociception and tolerance.

  The Journal of pharmacology and experimental therapeutics 20100901

• Effect of cadmium on resumption of respiration in cotyledons of germinating pea seeds.

  Ecotoxicology and environmental safety 20100901

• Molecular characterization of dopamine-derived quinones reactivity toward NADH and glutathione: implications for mitochondrial dysfunction in Parkinson disease.

  Biochimica et biophysica acta 20100901

• Metabolism and karyotype analysis of oocytes from patients with polycystic ovary syndrome.

  Human reproduction (Oxford, England) 20100901

• Transcriptional changes associated with ethanol tolerance in Saccharomyces cerevisiae.

  Applied microbiology and biotechnology 20100901

• Oxygen levels rapidly modulate Pseudomonas aeruginosa social behaviours via substrate limitation of PqsH.

  Molecular microbiology 20100901

• Design and synthesis of a long-wavelength latent fluorogenic substrate for salicylate hydroxylase: a useful fluorimetric indicator for analyte determination by dehydrogenase-coupled biosensors.

  Analytical chemistry 20100901

• Serum or target deprivation-induced neuronal death causes oxidative neuronal accumulation of Zn2+ and loss of NAD+.

  The European journal of neuroscience 20100901

• Establishment of steady-state metabolism of ethanol in perfused rat liver: the quantitative analysis using kinetic mechanism-based rate equations of alcohol dehydrogenase.

  Alcohol (Fayetteville, N.Y.) 20100901

• Synthesizing and salvaging NAD: lessons learned from Chlamydomonas reinhardtii.

  PLoS genetics 20100901

• Localization and function of the membrane-bound riboflavin in the Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) from Vibrio cholerae.

  The Journal of biological chemistry 20100827

• Effect of selected NAD+ analogues on mitochondria activity and proliferation of endothelial EA.hy926 cells.

  European journal of pharmacology 20100825

• Isonicotinic acid hydrazide conversion to Isonicotinyl-NAD by catalase-peroxidases.

  The Journal of biological chemistry 20100820

• Effects of oxygen on Shewanella decolorationis NTOU1 electron transfer to carbon-felt electrodes.

  Biosensors & bioelectronics 20100815

• Nicotinamide phosphoribosyltransferase/sirtuin 1 pathway is involved in human immunodeficiency virus type 1 Tat-mediated long terminal repeat transactivation.

  Journal of cellular biochemistry 20100815

• Reciprocal relationship between cytosolic NADH and ENOX2 inhibition triggers sphingolipid-induced apoptosis in HeLa cells.

  Journal of cellular biochemistry 20100815

• Nrk2b-mediated NAD+ production regulates cell adhesion and is required for muscle morphogenesis in vivo: Nrk2b and NAD+ in muscle morphogenesis.

  Developmental biology 20100815

• Mitochondrial free [Ca2+] increases during ATP/ADP antiport and ADP phosphorylation: exploration of mechanisms.

  Biophysical journal 20100809

• Pnc1p supports increases in cellular NAD(H) levels in response to internal or external oxidative stress.

  Biochemistry 20100803

• Structural basis for sirtuin function: what we know and what we don't.

  Biochimica et biophysica acta 20100801

• SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions.

  Biochimica et biophysica acta 20100801

• Biochemical effects of SIRT1 activators.

  Biochimica et biophysica acta 20100801

• The role of Sirt1: at the crossroad between promotion of longevity and protection against Alzheimer's disease neuropathology.

  Biochimica et biophysica acta 20100801

• Mitochondrial sirtuins.

  Biochimica et biophysica acta 20100801

• Deletion of the mitochondrial NADH kinase increases mitochondrial DNA stability and life span in the filamentous fungus Podospora anserina.

  Experimental gerontology 20100801

• Sirtuin chemical mechanisms.

  Biochimica et biophysica acta 20100801

• Oxidation of hydrogen sulfide remains a priority in mammalian cells and causes reverse electron transfer in colonocytes.

  Biochimica et biophysica acta 20100801

• Escherichia coli ferredoxin-NADP+ reductase and oxygen-insensitive nitroreductase are capable of functioning as ferric reductase and of driving the Fenton reaction.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20100801

• Spectroscopic properties of rubber oxygenase RoxA from Xanthomonas sp., a new type of dihaem dioxygenase.

  Microbiology (Reading, England) 20100801

• Redox modulation of Ecto-NOX1 in human platelets.

  Molecular membrane biology 20100801

• Nicotinate/nicotinamide mononucleotide adenyltransferase-mediated regulation of NAD biosynthesis protects guard cells from reactive oxygen species in ABA-mediated stomatal movement in Arabidopsis.

  Journal of experimental botany 20100801

• The reaction of NADPH with bovine mitochondrial NADH:ubiquinone oxidoreductase revisited: I. Proposed consequences for electron transfer in the enzyme.

  Journal of bioenergetics and biomembranes 20100801

• The reaction of NADPH with bovine mitochondrial NADH:ubiquinone oxidoreductase revisited: II. Comparison of the proposed working hypothesis with literature data.

  Journal of bioenergetics and biomembranes 20100801

• Quantitative magnetic resonance imaging of enzyme activity on the cell surface: in vitro and in vivo monitoring of ADP-ribosyltransferase 2 on T cells.

  Molecular imaging 20100801

• Gender-specific reduction in contraction is associated with increased estrogen receptor expression in single vascular smooth muscle cells of female rat.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100801

• Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases.

  Protein & cell 20100801

• Nampt/PBEF/visfatin and cancer.

  Cancer biology & therapy 20100715

• Clickable NAD analogues for labeling substrate proteins of poly(ADP-ribose) polymerases.

  Journal of the American Chemical Society 20100714

• Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts.

  The Journal of biological chemistry 20100702

• Protein deacetylase SIRT1 in the cytoplasm promotes nerve growth factor-induced neurite outgrowth in PC12 cells.

  FEBS letters 20100702

• Each conserved active site tyr in the three subunits of human isocitrate dehydrogenase has a different function.

  The Journal of biological chemistry 20100702

• Structural and catalytic properties of the D-3-hydroxybutyrate dehydrogenase from Pseudomonas aeruginosa.

  Current microbiology 20100701

• A possibility of nutriceuticals as an anti-aging intervention: activation of sirtuins by promoting mammalian NAD biosynthesis.

  Pharmacological research 20100701

• Midgut and fatbody mitochondrial transhydrogenase activities during larval-pupal development of the tobacco hornworm, Manduca sexta.

  Journal of insect physiology 20100701

• Phosphorylation of extrajunctional Cx43 in ischemic-preconditioned rat hearts.

  The Journal of surgical research 20100701

• Amperometric lactate biosensor for flow injection analysis based on a screen-printed carbon electrode containing Meldola's Blue-Reinecke salt, coated with lactate dehydrogenase and NAD+.

  Talanta 20100630

• Structural insight into substrate differentiation of the sugar-metabolizing enzyme galactitol dehydrogenase from Rhodobacter sphaeroides D.

  The Journal of biological chemistry 20100625

• Triazole-linked inhibitors of inosine monophosphate dehydrogenase from human and Mycobacterium tuberculosis.

  Journal of medicinal chemistry 20100624

• Metronomic administration of the drug GMX1777, a cellular NAD synthesis inhibitor, results in neuroblastoma regression and vessel maturation without inducing drug resistance.

  International journal of cancer 20100615

• Optical detection of single cell lactate release for cancer metabolic analysis.

  Analytical chemistry 20100615

• Sex differences in the phosphorylation of mitochondrial proteins result in reduced production of reactive oxygen species and cardioprotection in females.

  Circulation research 20100611

• Myoglobin redox form stabilization by compartmentalized lactate and malate dehydrogenases.

  Journal of agricultural and food chemistry 20100609

• Metabolic and transcriptional response to cofactor perturbations in Escherichia coli.

  The Journal of biological chemistry 20100604

• L-lactate generates hydrogen peroxide in purified rat liver mitochondria due to the putative L-lactate oxidase localized in the intermembrane space.

  FEBS letters 20100603

• Sevoflurane postconditioning protects isolated rat hearts against ischemia-reperfusion injury: the role of radical oxygen species, extracellular signal-related kinases 1/2 and mitochondrial permeability transition pore.

  Molecular biology reports 20100601

• Fasting promotes the expression of SIRT1, an NAD+ -dependent protein deacetylase, via activation of PPARalpha in mice.

  Molecular and cellular biochemistry 20100601

• Development and validation of a transcreener assay for detection of AMP- and GMP-producing enzymes.

  Assay and drug development technologies 20100601

• Metabolic flux analysis of wild-type Escherichia coli and mutants deficient in pyruvate-dissimilating enzymes during the fermentative metabolism of glucuronate.

  Microbiology (Reading, England) 20100601

• Molecular cloning and characterization of a malic enzyme gene from the oleaginous yeast Lipomyces starkeyi.

  Molecular biotechnology 20100601

• NAD(+) and metabolic regulation of age-related proteoxicity: A possible role for methylglyoxal?

  Experimental gerontology 20100601

• Glutathione peroxidase 1 protects mitochondria against hypoxia/reoxygenation damage in mouse hearts.

  Pflugers Archiv : European journal of physiology 20100601

• Pathobiology of renal-specific oxidoreductase/myo-inositol oxygenase in diabetic nephropathy: its implications in tubulointerstitial fibrosis.

  American journal of physiology. Renal physiology 20100601

• Pseudomonas fluorescens orchestrates a fine metabolic-balancing act to counter aluminium toxicity.

  Environmental microbiology 20100601

• Redox sensing by a Rex-family repressor is involved in the regulation of anaerobic gene expression in Staphylococcus aureus.

  Molecular microbiology 20100601

• Intracellular nicotinamide phosphoribosyltransferase protects against hepatocyte apoptosis and is down-regulated in nonalcoholic fatty liver disease.

  The Journal of clinical endocrinology and metabolism 20100601

• Age-associated differences in activation of Akt/GSK-3beta signaling pathways and inhibition of mitochondrial permeability transition pore opening in the rat heart.

  The journals of gerontology. Series A, Biological sciences and medical sciences 20100601

• [Nicotinamide adenine dinucleotide (NADH) in patients with chronic fatigue syndrome].

  Revista clinica espanola 20100601

• Optical redox ratio differentiates breast cancer cell lines based on estrogen receptor status.

  Cancer research 20100601

• A preclinical study on the rescue of normal tissue by nicotinic acid in high-dose treatment with APO866, a specific nicotinamide phosphoribosyltransferase inhibitor.

  Molecular cancer therapeutics 20100601

• Structure of photosynthetic glyceraldehyde-3-phosphate dehydrogenase (isoform A4) from Arabidopsis thaliana in complex with NAD.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20100601

• Enzymatic synthesis of some (15)N-labelled L-amino acids.

  Isotopes in environmental and health studies 20100601

• Effects of rested harvesting on muscle metabolite concentrations and K-values in Chinook salmon (Oncorhynchus tshawytscha) fillets during storage at 15 degrees C.

  Journal of food science 20100601

• Computational characterization for catalytic activities of human CD38's wild type, E226 and E146 mutants.

  Interdisciplinary sciences, computational life sciences 20100601

• Omega-3 but not omega-6 unsaturated fatty acids inhibit the cancer-specific ENOX2 of the HeLa cell surface with no effect on the constitutive ENOX1.

  Journal of dietary supplements 20100601

• Structural basis for NADH/NAD+ redox sensing by a Rex family repressor.

  Molecular cell 20100528

• Conserved structural motif for recognizing nicotinamide adenine dinucleotide in poly(ADP-ribose) polymerases and ADP-ribosylating toxins: implications for structure-based drug design.

  Journal of medicinal chemistry 20100527

• A thionine-based reversible redox sensor in a sequential injection system.

  Analytica chimica acta 20100523

• The development and evaluation of a conducting matrix for the electrochemical regeneration of the immobilised co-factor NAD(H) under continuous flow.

  Organic & biomolecular chemistry 20100521

• The metabolism and N-oxide reduction of olaquindox in liver preparations of rats, pigs and chicken.

  Toxicology letters 20100519

• Nicotinamide adenine dinucleotide-dependent binding of the neuronal Ca2+ sensor protein GCAP2 to photoreceptor synaptic ribbons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100512

• A slow, tight binding inhibitor of InhA, the enoyl-acyl carrier protein reductase from Mycobacterium tuberculosis.

  The Journal of biological chemistry 20100507

• Parallel synthesis of a series of non-functional ATP/NAD analogs with activity against trypanosomatid parasites.

  Molecular diversity 20100501

• Evidence for significantly enhancing reduction of Azo dyes in Escherichia coli by expressed cytoplasmic Azoreductase (AzoA) of Enterococcus faecalis.

  Protein and peptide letters 20100501

• Safety and efficacy of NAD depleting cancer drugs: results of a phase I clinical trial of CHS 828 and overview of published data.

  Cancer chemotherapy and pharmacology 20100501

• Characterization of thermostable FMN-dependent NADH azoreductase from the moderate thermophile Geobacillus stearothermophilus.

  Applied microbiology and biotechnology 20100501

• Lactate formation in Caldicellulosiruptor saccharolyticus is regulated by the energy carriers pyrophosphate and ATP.

  Metabolic engineering 20100501

• Quinolinate phosphoribosyl transferase, a key enzyme in de novo NAD(+) synthesis, suppresses spontaneous cell death by inhibiting overproduction of active-caspase-3.

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  Biotechnology journal 20100501

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  Chemphyschem : a European journal of chemical physics and physical chemistry 20100426

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  Journal of molecular biology 20100423

• CdTe, CdSe, and CdS nanocrystals for highly efficient regeneration of nicotinamide cofactor under visible light.

  Small (Weinheim an der Bergstrasse, Germany) 20100423

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  The journal of physical chemistry. B 20100422

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  Langmuir : the ACS journal of surfaces and colloids 20100420

• Challenges of steroid biotransformation with human cytochrome P450 monooxygenase CYP21 using resting cells of recombinant Schizosaccharomyces pombe.

  Journal of biotechnology 20100415

• An analytical method for the measurement of acid metabolites of tryptophan-NAD pathway and related acids in urine.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100415

• Elevated cytosolic Na+ increases mitochondrial formation of reactive oxygen species in failing cardiac myocytes.

  Circulation 20100413

• Evidence of altered guinea pig ventricular cardiomyocyte protein expression and growth in response to a 5 min in vitro exposure to H(2)O(2).

  Journal of proteome research 20100405

• Insight into the stereospecificity of short-chain thermus thermophilus alcohol dehydrogenase showing pro-S hydride transfer and prelog enantioselectivity.

  Protein and peptide letters 20100401

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• On the diversity of physicochemical environments experienced by identical ligands in binding pockets of unrelated proteins.

  Proteins 20100401

• Water-forming NADH oxidase protects Torulopsis glabrata against hyperosmotic stress.

  Yeast (Chichester, England) 20100401

• Extracellular beta-nicotinamide adenine dinucleotide (beta-NAD) promotes the endothelial cell barrier integrity via PKA- and EPAC1/Rac1-dependent actin cytoskeleton rearrangement.

  Journal of cellular physiology 20100401

• Cineole biodegradation: molecular cloning, expression and characterisation of (1R)-6beta-hydroxycineole dehydrogenase from Citrobacter braakii.

  Bioorganic chemistry 20100401

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  Hormones and behavior 20100401

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  Plant physiology 20100401

• Conditional modulation of NAD levels and metabolite profiles in Nicotiana sylvestris by mitochondrial electron transport and carbon/nitrogen supply.

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• Production and scavenging of nitric oxide by barley root mitochondria.

  Plant & cell physiology 20100401

• Structural and redox behavior of OxyVita, a zero-linked polymeric hemoglobin: comparison with natural acellular polymeric hemoglobins.

  Artificial cells, blood substitutes, and immobilization biotechnology 20100401

• NAD+ auxotrophy is bacteriocidal for the tubercle bacilli.

  Molecular microbiology 20100401

• Vitamin B3, the nicotinamide adenine dinucleotides and aging.

  Mechanisms of ageing and development 20100401

• Intracellular coenzymes as natural biomarkers for metabolic activities and mitochondrial anomalies.

  Biomarkers in medicine 20100401

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  Dalton transactions (Cambridge, England : 2003) 20100328

• Energy restriction as an antitumor target of thiazolidinediones.

  The Journal of biological chemistry 20100326

• Resveratrol is neuroprotective because it is not a direct activator of Sirt1-A hypothesis.

  Brain research bulletin 20100316

• First crystal structure of L-lysine 6-dehydrogenase as an NAD-dependent amine dehydrogenase.

  The Journal of biological chemistry 20100312

• Structural and functional characterization of plant aminoaldehyde dehydrogenase from Pisum sativum with a broad specificity for natural and synthetic aminoaldehydes.

  Journal of molecular biology 20100305

• Triazaspirodimethoxybenzoyls as selective inhibitors of mycobacterial lipoamide dehydrogenase .

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• Sequential injection kinetic flow assay for monitoring glycerol in a sugar fermentation process by Saccharomyces cerevisiae.

  Applied biochemistry and biotechnology 20100301

• Transhydrogenase and the anaerobic mitochondrial metabolism of adult Hymenolepis diminuta.

  Parasitology 20100301

• Astrocytic poly(ADP-ribose) polymerase-1 activation leads to bioenergetic depletion and inhibition of glutamate uptake capacity.

  Glia 20100301

• Alteration of hydrogen metabolism of ldh-deleted Enterobacter aerogenes by overexpression of NAD+-dependent formate dehydrogenase.

  Applied microbiology and biotechnology 20100301

• Immobilization of intracellular carbonyl reductase from Geotrichum candidum for the stereoselective reduction of 1-naphthyl ketone.

  Bioresource technology 20100301

• AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol.

  Diabetes 20100301

• The effect of tert-butylhydroquinone-induced oxidative stress in MDBK cells using XTT assay: implication of tert-butylhydroquinone-induced NADPH generating enzymes.

  The Journal of veterinary medical science 20100301

• Two different electron transfer pathways may involve in azoreduction in Shewanella decolorationis S12.

  Applied microbiology and biotechnology 20100301

• Biochemical characterization of a recombinant short-chain NAD(H)-dependent dehydrogenase/reductase from Sulfolobus acidocaldarius.

  Extremophiles : life under extreme conditions 20100301

• Isoniazid-resistance conferring mutations in Mycobacterium tuberculosis KatG: catalase, peroxidase, and INH-NADH adduct formation activities.

  Protein science : a publication of the Protein Society 20100301

• Physiological requirements for carbonate precipitation during biofilm development of Bacillus subtilis etfA mutant.

  FEMS microbiology ecology 20100301

• The actions of fisetin on glucose metabolism in the rat liver.

  Cell biochemistry and function 20100301

• Gene cloning and characterization of dihydrolipoamide dehydrogenase from Microbacterium luteolum: A useful enzymatic regeneration system of NAD+ from NADH.

  Journal of bioscience and bioengineering 20100301

• Excessive tryptophan catabolism along the kynurenine pathway precedes ongoing sepsis in critically ill patients.

  Anaesthesia and intensive care 20100301

• Recent progress in the identification and development of InhA direct inhibitors of Mycobacterium tuberculosis.

  Mini reviews in medicinal chemistry 20100301

• Wld(S), Nmnats and axon degeneration--progress in the past two decades.

  Protein & cell 20100301

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  Brain research 20100226

• NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100224

• Mechanism and inhibition of the FabV enoyl-ACP reductase from Burkholderia mallei.

  Biochemistry 20100216

• Decolorization of malachite green by cytochrome c in the mitochondria of the fungus Cunninghamella elegans.

  Archives of biochemistry and biophysics 20100215

• Electrochemical determination of NADH and ethanol based on ionic liquid-functionalized graphene.

  Biosensors & bioelectronics 20100215

• Facilitation of NADH electro-oxidation at treated carbon nanotubes.

  Analytical chemistry 20100215

• Novel 3-arylideneindolin-2-ones as inhibitors of NAD+ -dependent histone deacetylases (sirtuins).

  Journal of medicinal chemistry 20100211

• Resveratrol modulates tumor cell proliferation and protein translation via SIRT1-dependent AMPK activation.

  Journal of agricultural and food chemistry 20100210

• Pharmacophore mapping via cross-relaxation during adiabatic fast passage.

  Journal of the American Chemical Society 20100210

• Carbon nanotubes based electrochemical biosensor for detection of formaldehyde released from a cancer cell line treated with formaldehyde-releasing anticancer prodrugs.

  Bioelectrochemistry (Amsterdam, Netherlands) 20100201

• Cross-talk between L-type Ca2+ channels and mitochondria.

  Clinical and experimental pharmacology & physiology 20100201

• Structural features of the NAD-dependent in situ retinoic acid supply system in esophageal mucosa.

  Alcoholism, clinical and experimental research 20100201

• Flocculation of dimorphic yeast Benjaminiella poitrasii is altered by modulation of NAD-glutamate dehydrogenase.

  Bioresource technology 20100201

• Xanthine dehydrogenase AtXDH1 from Arabidopsis thaliana is a potent producer of superoxide anions via its NADH oxidase activity.

  Plant molecular biology 20100201

• Dual role of Zn2+ in maintaining structural integrity and suppressing deacetylase activity of SIRT1.

  Journal of inorganic biochemistry 20100201

• The ginsenoside protopanaxatriol protects endothelial cells from hydrogen peroxide-induced cell injury and cell death by modulating intracellular redox status.

  Free radical biology & medicine 20100201

• Purification and characterization of vanillin dehydrogenases from alkaliphile Micrococcus sp. TA1 and neutrophile Burkholderia cepacia TM1.

  FEMS microbiology letters 20100201

• Mechanism of glyceraldehyde-3-phosphate dehydrogenase inactivation by tyrosine nitration.

  Protein science : a publication of the Protein Society 20100201

• Ergot alkaloid biosynthesis in Aspergillus fumigatus: conversion of chanoclavine-I to chanoclavine-I aldehyde catalyzed by a short-chain alcohol dehydrogenase FgaDH.

  Archives of microbiology 20100201

• Efficacy of combining GMX1777 with radiation therapy for human head and neck carcinoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20100201

• Toward the virtual screening of potential drugs in the homology modeled NAD+ dependent DNA ligase from Mycobacterium tuberculosis.

  Protein and peptide letters 20100201

• Bovine heart NADH-ubiquinone oxidoreductase contains one molecule of ubiquinone with ten isoprene units as one of the cofactors.

  Biochemistry 20100126

• A flow injection system, comprising a biosensor based on a screen-printed carbon electrode containing Meldola's Blue-Reinecke salt coated with glucose dehydrogenase, for the measurement of glucose.

  Analytical biochemistry 20100115

• Iron oxide/carbon black (Fe2O3/CB) composite electrode for the detection of reduced nicotinamide cofactors using an amperometric method under a low overpotential.

  Biosensors & bioelectronics 20100115

• Characterization of chlorophenol 4-monooxygenase (TftD) and NADH:FAD oxidoreductase (TftC) of Burkholderia cepacia AC1100.

  The Journal of biological chemistry 20100115

• Simultaneous kinetic determination of 3-hydroxybutyrate and 3-hydroxyvalerate in biopolymer degradation processes.

  Talanta 20100115

• Characterization of the East Asian variant of aldehyde dehydrogenase-2: bioactivation of nitroglycerin and effects of Alda-1.

  The Journal of biological chemistry 20100108

• Ethanol enhances hepatitis C virus replication through lipid metabolism and elevated NADH/NAD+.

  The Journal of biological chemistry 20100108

• Cardioprotective activity of a novel and potent competitive inhibitor of lactate dehydrogenase.

  FEBS letters 20100104

• Cloning, expression, and characterization of a novel (S)-specific alcohol dehydrogenase from Lactobacillus kefir.

  Applied biochemistry and biotechnology 20100101

• Conformational changes and catalysis by alcohol dehydrogenase.

  Archives of biochemistry and biophysics 20100101

• Early neural and vascular dysfunctions in diabetic rats are largely sequelae of increased sorbitol oxidation.

  Antioxidants & redox signaling 20100101

• Enzymatic reduction of complex redox dyes using NADH-dependent reductase from Bacillus subtilis coupled with cofactor regeneration.

  Applied microbiology and biotechnology 20100101

• Integrated network systems and evolutionary developmental endocrinology.

  Medical hypotheses 20100101

• Engineering the Pichia pastoris methanol oxidation pathway for improved NADH regeneration during whole-cell biotransformation.

  Metabolic engineering 20100101

• Using regulatory information to manipulate glycerol metabolism in Saccharomyces cerevisiae.

  Applied microbiology and biotechnology 20100101

• Energetic performance is improved by specific activation of K+ fluxes through K(Ca) channels in heart mitochondria.

  Biochimica et biophysica acta 20100101

• Nmnat2 delays axon degeneration in superior cervical ganglia dependent on its NAD synthesis activity.

  Neurochemistry international 20100101

• Mechanistic model for prediction of formate dehydrogenase kinetics under industrially relevant conditions.

  Biotechnology progress 20100101

• Contributions of active site residues to cofactor binding and catalysis of 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase.

  Biochimica et biophysica acta 20100101

• Doubling the catabolic reducing power (NADH) output of Escherichia coli fermentation for production of reduced products.

  Biotechnology progress 20100101

• Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity.

  American journal of physiology. Endocrinology and metabolism 20100101

• Pyridine salvage and nicotinic acid conjugate synthesis in leaves of mangrove species.

  Phytochemistry 20100101

• Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats.

  Mechanisms of ageing and development 20100101

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  Physiological research 20100101

• Aging-related nicotinamide adenine dinucleotide oxidase response to dietary supplementation: the French paradox revisited.

  Rejuvenation research 20100101

• Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons.

  The FEBS journal 20100101

• The structure of dihydrodipicolinate reductase (DapB) from Mycobacterium tuberculosis in three crystal forms.

  Acta crystallographica. Section D, Biological crystallography 20100101

• Role of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazide.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20100101

• A novel whole-cell biocatalyst with NAD+ regeneration for production of chiral chemicals.

  PloS one 20100101

• The dopamine-D2-receptor agonist ropinirole dose-dependently blocks the Ca2+-triggered permeability transition of mitochondria.

  Biochimica et biophysica acta 20100101

• What are the sources of hydrogen peroxide production by heart mitochondria?

  Biochimica et biophysica acta 20100101

• Sperm mitochondria diaphorase activity--a gene mapping study of recombinant inbred strains of mice.

  The International journal of developmental biology 20100101

• In vivo native fluorescence spectroscopy and nicotinamide adinine dinucleotide/flavin adenine dinucleotide reduction and oxidation states of oral submucous fibrosis for chemopreventive drug monitoring.

  Journal of biomedical optics 20100101

• Role of mitochondria in beta-cell function and dysfunction.

  Advances in experimental medicine and biology 20100101

• CYB5R3: a key player in aerobic metabolism and aging?

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  BMC bioinformatics 20100101

• Comparative genomics of metabolic networks of free-living and parasitic eukaryotes.

  BMC genomics 20100101

• Improvement of coenzyme Q(10) production by increasing the NADH/NAD(+) ratio in Agrobacterium tumefaciens.

  Bioscience, biotechnology, and biochemistry 20100101

• The unique kinetic behavior of the very large NAD-dependent glutamate dehydrogenase from Janthinobacterium lividum.

  Bioscience, biotechnology, and biochemistry 20100101

• An AP-1-like transcription factor, NAP-1, regulates expression of the glutathione S-transferase and NADH:flavin oxidoreductase genes in Neurospora crassa.

  Bioscience, biotechnology, and biochemistry 20100101

• Natural occurrence of 2',5'-linked heteronucleotides in marine sponges.

  Marine drugs 20100101

• Carbon nanotube biosensors based on electrochemical detection.

  Methods in molecular biology (Clifton, N.J.) 20100101

• Oxidative stress and NAD+ in ischemic brain injury: current advances and future perspectives.

  Current medicinal chemistry 20100101

• Chlorella vulgaris aldehyde reductase is capable of functioning as ferric reductase and of driving the fenton reaction in the presence of free flavin.

  Bioscience, biotechnology, and biochemistry 20100101

• Glutamate dehydrogenase and glutamine synthetase are regulated in response to nitrogen availability in Myocbacterium smegmatis.

  BMC microbiology 20100101

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  Radiatsionnaia biologiia, radioecologiia 20100101

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  Redox report : communications in free radical research 20100101

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  Advances in clinical chemistry 20100101

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  Methods in molecular biology (Clifton, N.J.) 20100101

• Application of an electrochemical NAD+ recycling system involving a string-like carbon fiber to an enzyme reactor.

  Bioscience, biotechnology, and biochemistry 20100101

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  Bioscience, biotechnology, and biochemistry 20100101

• Sirtuin family: a link to metabolic signaling and senescence.

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  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20100101

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  International journal of nanomedicine 20100101

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  Neurology India 20100101

• Identification and biochemical characterization of a thermostable malate dehydrogenase from the mesophile Streptomyces coelicolor A3(2).

  Bioscience, biotechnology, and biochemistry 20100101

• High-affinity inhibitors of human NAD-dependent 15-hydroxyprostaglandin dehydrogenase: mechanisms of inhibition and structure-activity relationships.

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  Biochemistry 20091222

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  Inorganic chemistry 20091221

• Influence of organic and inorganic compounds on oxidoreductive decolorization of sulfonated azo dye C.I. Reactive Orange 16.

  Journal of hazardous materials 20091215

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  Analytical biochemistry 20091215

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• Poly(brilliant cresyl blue)-carbonnanotube modified electrodes for determination of NADH and fabrication of ethanol dehydrogenase-based biosensor.

  Biosensors & bioelectronics 20091215

• Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5'-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside.

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• Enzyme-based NAND and NOR logic gates with modular design.

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  World journal of gastroenterology 20091207

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  The international journal of biochemistry & cell biology 20091201

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  Journal of physiology and biochemistry 20091201

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  Bioorganic & medicinal chemistry 20091115

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  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20091101

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  Proteins 20091101

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  Experimental biology and medicine (Maywood, N.J.) 20091101

• Salmonella enterica serotype Typhimurium DT104 ArtA-dependent modification of pertussis toxin-sensitive G proteins in the presence of [32P]NAD.

  Microbiology (Reading, England) 20091101

• Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD+ levels and SIRT inhibition.

  Experimental hematology 20091101

• Characterization of SgcE6, the flavin reductase component supporting FAD-dependent halogenation and hydroxylation in the biosynthesis of the enediyne antitumor antibiotic C-1027.

  FEMS microbiology letters 20091101

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  Development (Cambridge, England) 20091101

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  Nature medicine 20091101

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  The FEBS journal 20091101

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  Circulation research 20091023

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  Science (New York, N.Y.) 20091023

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  Chemistry (Weinheim an der Bergstrasse, Germany) 20091019

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  The Journal of biological chemistry 20091016

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  The Journal of biological chemistry 20091016

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  Biophysical journal 20091007

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  The Journal of biological chemistry 20091002

• A novel protein that binds to dnrN-dnrO intergenic region of Streptomyces peucetius purified by DNA affinity capture has dihydrolipoamide dehydrogenase activity.

  Protein expression and purification 20091001

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  Biotechnology and bioengineering 20091001

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  Biochimica et biophysica acta 20091001

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  Small (Weinheim an der Bergstrasse, Germany) 20091001

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  Biotechnology letters 20091001

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  Plant physiology 20091001

• Melatonin protects against heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening.

  American journal of physiology. Heart and circulatory physiology 20091001

• Computational design of Candida boidinii xylose reductase for altered cofactor specificity.

  Protein science : a publication of the Protein Society 20091001

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  Journal of bioscience and bioengineering 20091001

• Tacrolimus ameliorates metabolic disturbance and oxidative stress caused by hepatitis C virus core protein: analysis using mouse model and cultured cells.

  The American journal of pathology 20091001

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  Wei sheng wu xue bao = Acta microbiologica Sinica 20091001

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  The Journal of biological chemistry 20090925

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  The Journal of biological chemistry 20090925

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  Molecular cell 20090924

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  Life sciences 20090923

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  Organic & biomolecular chemistry 20090921

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  The Journal of organic chemistry 20090904

• Kinetics of the hydride reduction of an NAD(+) analogue by isopropyl alcohol in aqueous and acetonitrile solutions: solvent effects, deuterium isotope effects, and mechanism.

  The Journal of organic chemistry 20090904

• Activation of translation via reduction by thioredoxin-thioredoxin reductase in Saccharomyces cerevisiae.

  FEBS letters 20090903

• Electrochemical and solid-phase synthetic modification of glassy carbon electrodes with dihydroxybenzene compounds and the electrocatalytic oxidation of NADH.

  Bioelectrochemistry (Amsterdam, Netherlands) 20090901

• Regulation of glomerular heparanase expression by aldosterone, angiotensin II and reactive oxygen species.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090901

• H(2)O(2)-mediated modulation of cytosolic signaling and organelle function in rat hippocampus.

  Pflugers Archiv : European journal of physiology 20090901

• Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme.

  Cellular and molecular life sciences : CMLS 20090901

• Synergistic effect of mediator-carbon nanotube composites for dehydrogenases and peroxidases based biosensors.

  Bioelectrochemistry (Amsterdam, Netherlands) 20090901

• Estrogen can signal through multiple pathways to regulate oocyte cyst breakdown and primordial follicle assembly in the neonatal mouse ovary.

  The Journal of endocrinology 20090901

• Carbon fluxes of xylose-consuming Saccharomyces cerevisiae strains are affected differently by NADH and NADPH usage in HMF reduction.

  Applied microbiology and biotechnology 20090901

• Experimental conditions affect the site of tetrazolium violet reduction in the electron transport chain of Lactococcus lactis.

  Microbiology (Reading, England) 20090901

• Role of tryptophan 95 in substrate specificity and structural stability of Sulfolobus solfataricus alcohol dehydrogenase.

  Extremophiles : life under extreme conditions 20090901

• Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells.

  Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20090901

• Interaction of nitric oxide with the activity of cytosolic NADH/cytochrome c electron transport system.

  Archives of biochemistry and biophysics 20090901

• Bipartite recognition and conformational sampling mechanisms for hydride transfer from nicotinamide coenzyme to FMN in pentaerythritol tetranitrate reductase.

  The FEBS journal 20090901

• Storage and secretion of beta-NAD, ATP and dopamine in NGF-differentiated rat pheochromocytoma PC12 cells.

  The European journal of neuroscience 20090901

• The role of sirtuins in the control of metabolic homeostasis.

  Annals of the New York Academy of Sciences 20090901

• [Quantitative detection of NADH by in vitro bacterial luciferase bioluminescent].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20090901

• The effect of substrate, ADP and uncoupler on the respiration of tomato pollen during incubation in vitro at moderately high temperature.

  Sexual plant reproduction 20090901

• Nicotinamide phosphoribosyltransferase regulates cell survival through NAD+ synthesis in cardiac myocytes.

  Circulation research 20090828

• Targeting NAD biosynthesis in bacterial pathogens: Structure-based development of inhibitors of nicotinate mononucleotide adenylyltransferase NadD.

  Chemistry & biology 20090828

• Diastereocontrolled electrophilic fluorinations of 2-deoxyribonolactone: syntheses of all corresponding 2-deoxy-2-fluorolactones and 2'-deoxy-2'-fluoro-NAD+s.

  The Journal of organic chemistry 20090821

• Functional role for the conformationally mobile phenylalanine 223 in the reaction of methylenetetrahydrofolate reductase from Escherichia coli.

  Biochemistry 20090818

• Boric acid inhibits stored Ca2+ release in DU-145 prostate cancer cells.

  Cell biology and toxicology 20090801

• Converting NADH to NAD+ by nicotinamide nucleotide transhydrogenase as a novel strategy against mitochondrial pathologies during aging.

  Biogerontology 20090801

• Caloric restriction counteracts age-related changes in the activities of sorbitol metabolizing enzymes from mouse liver.

  Biogerontology 20090801

• Nitrosative stress, protein tyrosine nitration, PARP activation and NAD depletion in the kidneys of rats after single dose of cyclophosphamide.

  Clinical and experimental nephrology 20090801

• Central metabolism in Mycobacterium smegmatis during the transition from O2-rich to O2-poor conditions as studied by isotopomer-assisted metabolite analysis.

  Biotechnology letters 20090801

• Physiology of Aspergillus niger in oxygen-limited continuous cultures: Influence of aeration, carbon source concentration and dilution rate.

  Biotechnology and bioengineering 20090801

• Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: I. The role of arsenolysis.

  Toxicological sciences : an official journal of the Society of Toxicology 20090801

• mu-opioid receptor-stimulated synthesis of reactive oxygen species is mediated via phospholipase D2.

  Journal of neurochemistry 20090801

• Redox activated MAP kinase death signaling cascade initiated by ASK1 is not activated in female mice following MPTP: novel mechanism of neuroprotection.

  Neurotoxicity research 20090801

• Inhibition of succinate-linked respiration and complex II activity by hydrogen peroxide.

  Archives of biochemistry and biophysics 20090801

• Selective inhibition of nicotinamide adenine dinucleotide kinases by dinucleoside disulfide mimics of nicotinamide adenine dinucleotide analogues.

  Bioorganic & medicinal chemistry 20090801

• Axonal and cell body protection by nicotinamide adenine dinucleotide in tumor necrosis factor-induced optic neuropathy.

  Journal of neuropathology and experimental neurology 20090801

• Cloning, purification and characterization of an NAD-Dependent D-Arabitol dehydrogenase from acetic acid bacterium, Acetobacter suboxydans.

  The protein journal 20090801

• Photoinduced DNA cleavage by alpha-, beta-, and gamma-cyclodextrin-bicapped C60 supramolecular complexes.

  Environmental science & technology 20090801

• [Exogenous succinate reduces vibration-induced disorders of energy metabolism in rabbit cardiomyocytes].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20090801

• Nanoparticle-induced potentiometric biosensing of NADH at copper ion-selective electrodes.

  The Analyst 20090801

• Redox-linked conformational dynamics in apoptosis-inducing factor.

  Journal of molecular biology 20090731

• Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promoters.

  The Journal of biological chemistry 20090724

• Role of the general base Glu-268 in nitroglycerin bioactivation and superoxide formation by aldehyde dehydrogenase-2.

  The Journal of biological chemistry 20090724

• Electrochemical sensing and biosensing platform based on chemically reduced graphene oxide.

  Analytical chemistry 20090715

• Structure and function of an ADP-ribose-dependent transcriptional regulator of NAD metabolism.

  Structure (London, England : 1993) 20090715

• Xanthine oxidase-induced neuronal death via the oxidation of NADH: prevention by micromolar EDTA.

  Brain research 20090714

• Protective role of estrogen receptor-alpha on lower chlorinated PCB congener-induced DNA damage and repair in human tumoral breast cells.

  Toxicology letters 20090710

• Effect of succinate sodium on the metmyoglobin reduction and color stability of beef patties.

  Journal of agricultural and food chemistry 20090708

• NAD(P)H- and superoxide-dependent nitric oxide degradation by rat liver mitochondria.

  FEBS letters 20090707

• Protein nitration, PARP activation and NAD+ depletion may play a critical role in the pathogenesis of cyclophosphamide-induced hemorrhagic cystitis in the rat.

  Cancer chemotherapy and pharmacology 20090701

• Purification, properties, and kinetic studies of cytoplasmic malate dehydrogenase from Taenia solium cysticerci.

  Parasitology research 20090701

• Reversal of coenzyme specificity and improvement of catalytic efficiency of Pichia stipitis xylose reductase by rational site-directed mutagenesis.

  Biotechnology letters 20090701

• Quantitation of NAD+ biosynthesis from the salvage pathway in Saccharomyces cerevisiae.

  Yeast (Chichester, England) 20090701

• Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons.

  Journal of neurochemistry 20090701

• Metabolic benefits from Sirt1 and Sirt1 activators.

  Current opinion in clinical nutrition and metabolic care 20090701

• Efficacy of acetaminophen in skin B16-F0 melanoma tumor-bearing C57BL/6 mice.

  International journal of oncology 20090701

• Characterization of a soluble oxidoreductase from the thermophilic bacterium Carboxydothermus ferrireducens.

  Extremophiles : life under extreme conditions 20090701

• Differential regulation of P2X7 receptor activation by extracellular nicotinamide adenine dinucleotide and ecto-ADP-ribosyltransferases in murine macrophages and T cells.

  Journal of immunology (Baltimore, Md. : 1950) 20090701

• Saline-linked surface radiofrequency ablation: a safe and effective method of surface ablation of hepatic metastatic colorectal cancer.

  Annals of surgery 20090701

• Elevated poly-(ADP-ribose)-polymerase activity sensitizes retinoblastoma-deficient cells to DNA damage-induced necrosis.

  Molecular cancer research : MCR 20090701

• Application of artificial neural networks in the prediction of product distribution in electrophoretically mediated microanalysis.

  Electrophoresis 20090701

• Electrochemical and biochemical analysis of ethanol fermentation of zymomonas mobilis KCCM11336.

  Journal of microbiology and biotechnology 20090701

• Induced fit and equilibrium dynamics for high catalytic efficiency in ferredoxin-NADP(H) reductases.

  Biochemistry 20090623

• Assimilation of endogenous nicotinamide riboside is essential for calorie restriction-mediated life span extension in Saccharomyces cerevisiae.

  The Journal of biological chemistry 20090619

• A link between hinge-bending domain motions and the temperature dependence of catalysis in 3-isopropylmalate dehydrogenase.

  Biophysical journal 20090617

• Enzyme-modified nanoporous gold-based electrochemical biosensors.

  Biosensors & bioelectronics 20090615

• The catalytic mechanism of NADH-dependent reduction of 9,10-phenanthrenequinone by Candida tenuis xylose reductase reveals plasticity in an aldo-keto reductase active site.

  The Biochemical journal 20090612

• Role of the anion-binding site in catalysis and regulation of Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase.

  Biochemistry 20090609

• Evidence for regulation of mitochondrial function by the L-type Ca2+ channel in ventricular myocytes.

  Journal of molecular and cellular cardiology 20090601

• The ins and outs of Na(+) bioenergetics in Acetobacterium woodii.

  Biochimica et biophysica acta 20090601

• Regulation of glycerol metabolism in Enterobacter aerogenes NBRC12010 under electrochemical conditions.

  Applied microbiology and biotechnology 20090601

• Preclinical development of the nicotinamide phosphoribosyl transferase inhibitor prodrug GMX1777.

  Anti-cancer drugs 20090601

• Two novel metal-independent long-chain alkyl alcohol dehydrogenases from Geobacillus thermodenitrificans NG80-2.

  Microbiology (Reading, England) 20090601

• Prevention of hepatocarcinogenesis and increased susceptibility to acetaminophen-induced liver failure in transaldolase-deficient mice by N-acetylcysteine.

  The Journal of clinical investigation 20090601

• Defective myotilin homodimerization caused by a novel mutation in MYOT exon 9 in the first Japanese limb girdle muscular dystrophy 1A patient.

  Journal of neuropathology and experimental neurology 20090601

• Cloning, expression, and characterization of xylose reductase with higher activity from Candida tropicalis.

  Journal of microbiology (Seoul, Korea) 20090601

• Fabrication of a microfluidic enzyme reactor utilizing magnetic beads.

  Electrophoresis 20090601

• Consideration of diurnal variations in human blood NAD and NADP concentrations.

  Journal of nutritional science and vitaminology 20090601

• Effect of transient and permanent permeability transition pore opening on NAD(P)H localization in intact cells.

  The Journal of biological chemistry 20090529

• Parallel pathways and free-energy landscapes for enzymatic hydride transfer probed by hydrostatic pressure.

  Chembiochem : a European journal of chemical biology 20090525

• Highly ordered mesoporous carbons-based glucose/O2 biofuel cell.

  Biosensors & bioelectronics 20090515

• Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo.

  Biochemical pharmacology 20090515

• Tryptophan repressor-binding proteins from Escherichia coli and Archaeoglobus fulgidus as new catalysts for 1,4-dihydronicotinamide adenine dinucleotide-dependent amperometric biosensors and biofuel cells.

  Analytical chemistry 20090515

• The crystal structure of Aquifex aeolicus prephenate dehydrogenase reveals the mode of tyrosine inhibition.

  The Journal of biological chemistry 20090508

• Regulation of glycolytic oscillations by mitochondrial and plasma membrane H+-ATPases.

  Biophysical journal 20090506

• On-line characterization of physiological state in poly(beta-hydroxybutyrate) production by Wautersia eutropha.

  Applied biochemistry and biotechnology 20090501

• Threonine-deficient diets induced changes in hepatic bioenergetics.

  American journal of physiology. Gastrointestinal and liver physiology 20090501

• Effects of glutathione reductase inhibition on cellular thiol redox state and related systems.

  Archives of biochemistry and biophysics 20090501

• Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1.

  Science (New York, N.Y.) 20090501

• Effects of aerobic and anaerobic metabolic inhibitors on avian intrapulmonary chemoreceptors.

  American journal of physiology. Regulatory, integrative and comparative physiology 20090501

• Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis.

  Science (New York, N.Y.) 20090501

• Determination of total bile acid levels using a thick-film screen-printed Ir/C sensor for the detection of liver disease.

  The Analyst 20090501

• Circadian rhythms. A circadian loop asSIRTs itself.

  Science (New York, N.Y.) 20090501

• The role of acetaldehyde and glycerol in the adaptation to ethanol stress of Saccharomyces cerevisiae and other yeasts.

  FEMS yeast research 20090501

• Comparative enzymatic analysis of azoreductases from Bacillus sp. B29.

  Bioscience, biotechnology, and biochemistry 20090501

• Cofactor recycling for selective enzymatic biotransformation of cinnamaldehyde to cinnamyl alcohol.

  Bioscience, biotechnology, and biochemistry 20090501

• Biosensor based on glutamate dehydrogenase immobilized in chitosan for the determination of ammonium in water samples.

  Analytical biochemistry 20090501

• Improving d-mannitol productivity of Escherichia coli: impact of NAD, CO2 and expression of a putative sugar permease from Leuconostoc pseudomesenteroides.

  Metabolic engineering 20090501

• Pyridine nucleotide cycling and control of intracellular redox state in relation to poly (ADP-ribose) polymerase activity and nuclear localization of glutathione during exponential growth of Arabidopsis cells in culture.

  Molecular plant 20090501

• The quaternary structure of NADPH thioredoxin reductase C is redox-sensitive.

  Molecular plant 20090501

• The rationale for targeting the NAD/NADH cofactor binding site of parasitic S-adenosyl-L-homocysteine hydrolase for the design of anti-parasitic drugs.

  Nucleosides, nucleotides & nucleic acids 20090501

• Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090429

• Hydrolase regulates NAD+ metabolites and modulates cellular redox.

  The Journal of biological chemistry 20090424

• AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity.

  Nature 20090423

• Inositol 1,4,5-triphosphate receptors and NAD(P)H mediate Ca2+ signaling required for hypoxic preconditioning of hippocampal neurons.

  Neuroscience 20090421

• Network analysis of biochemical logic for noise reduction and stability: a system of three coupled enzymatic and gates.

  The journal of physical chemistry. B 20090416

• Dopamine sensitized nanoporous TiO2 film on electrodes: photoelectrochemical sensing of NADH under visible irradiation.

  Biosensors & bioelectronics 20090415

• Supramolecular cocaine-aptamer complexes activate biocatalytic cascades.

  Journal of the American Chemical Society 20090415

• Simultaneous accumulation and degradation of polyhydroxyalkanoates: futile cycle or clever regulation?

  Biomacromolecules 20090413

• Critical roles of subunit NuoH (ND1) in the assembly of peripheral subunits with the membrane domain of Escherichia coli NDH-1.

  The Journal of biological chemistry 20090410

• Production of panic-like symptoms by lactate is associated with increased neural firing and oxidation of brain redox in the rat hippocampus.

  Neuroscience letters 20090410

• Redox-switch modulation of human SSADH by dynamic catalytic loop.

  The EMBO journal 20090408

• Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD.

  Biochemistry 20090407

• Two-photon autofluorescence dynamics imaging reveals sensitivity of intracellular NADH concentration and conformation to cell physiology at the single-cell level.

  Journal of photochemistry and photobiology. B, Biology 20090402

• The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies.

  Blood 20090402

• L: -2-Hydroxyglutaric aciduria, a disorder of metabolite repair.

  Journal of inherited metabolic disease 20090401

• The Wolbachia endosymbiont of Brugia malayi has an active phosphoglycerate mutase: a candidate target for anti-filarial therapies.

  Parasitology research 20090401

• Nampt: linking NAD biology, metabolism and cancer.

  Trends in endocrinology and metabolism: TEM 20090401

• Pharmacological stimulation of NADH oxidation ameliorates obesity and related phenotypes in mice.

  Diabetes 20090401

• Studies of interaction of homo-dimeric ferredoxin-NAD(P)+ oxidoreductases of Bacillus subtilis and Rhodopseudomonas palustris, that are closely related to thioredoxin reductases in amino acid sequence, with ferredoxins and pyridine nucleotide coenzymes.

  Biochimica et biophysica acta 20090401

• Contribution of nitric oxide, superoxide anion, and peroxynitrite to activation of mitochondrial apoptotic signaling in hippocampal CA3 subfield following experimental temporal lobe status epilepticus.

  Epilepsia 20090401

• Contribution of NADH increases to ethanol's inhibition of retinol oxidation by human ADH isoforms.

  Alcoholism, clinical and experimental research 20090401

• Cyclic ADP-ribose links metabolism to multiple fission in the dinoflagellate Crypthecodinium cohnii.

  Cell calcium 20090401

• Gene identification and characterization of 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase, an NAD+-dependent dismutase.

  Journal of biochemistry 20090401

• Impact of overexpressing NADH kinase on glucose and xylose metabolism in recombinant xylose-utilizing Saccharomyces cerevisiae.

  Applied microbiology and biotechnology 20090401

• Regulation of active site coupling in glutamine-dependent NAD(+) synthetase.

  Nature structural & molecular biology 20090401

• Neuroprotective potential of combination of resveratrol and 4-amino 1,8 naphthalimide in experimental diabetic neuropathy: focus on functional, sensorimotor and biochemical changes.

  Free radical research 20090401

• Detection of free radical reactions in an aqueous sample induced by low linear-energy-transfer irradiation.

  Biological & pharmaceutical bulletin 20090401

• Structure of D-3-hydroxybutyrate dehydrogenase prepared in the presence of the substrate D-3-hydroxybutyrate and NAD+.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20090401

• Regulation of mitochondrial Ca2+ and its effects on energetics and redox balance in normal and failing heart.

  Journal of bioenergetics and biomembranes 20090401

• Control and regulation of integrated mitochondrial function in metabolic and transport networks.

  International journal of molecular sciences 20090401

• On the free energy that drove primordial anabolism.

  International journal of molecular sciences 20090401

• Structure-guided Mutational Analysis of the Nucleotidyltransferase Domain of Escherichia coli DNA Ligase (LigA).

  The Journal of biological chemistry 20090327

• The Electron Transfer Pathway of the Na+-pumping NADH:Quinone Oxidoreductase from Vibrio cholerae.

  The Journal of biological chemistry 20090327

• CtBP1/BARS Gly172-->Glu mutant structure: impairing NAD(H)-binding and dimerization.

  Biochemical and biophysical research communications 20090327

• Biochemical characterization of human epidermal retinol dehydrogenase 2.

  Chemico-biological interactions 20090316

• The conserved R166 residue of ALDH5A (succinic semialdehyde dehydrogenase) has multiple functional roles.

  Chemico-biological interactions 20090316

• Electrochemiluminescence detection of NADH and ethanol based on partial sulfonation of sol-gel network with gold nanoparticles.

  Biosensors & bioelectronics 20090315

• Physiologically relevant online electrochemical method for continuous and simultaneous monitoring of striatum glucose and lactate following global cerebral ischemia/reperfusion.

  Analytical chemistry 20090315

• Calcium signaling in brain mitochondria: interplay of malate aspartate NADH shuttle and calcium uniporter/mitochondrial dehydrogenase pathways.

  The Journal of biological chemistry 20090313

• Comparison studies of the human heart and Bacillus stearothermophilus lactate dehydrogreanse by transition path sampling.

  The journal of physical chemistry. A 20090312

• Reduction of hydrophilic ubiquinones by the flavin in mitochondrial NADH:ubiquinone oxidoreductase (Complex I) and production of reactive oxygen species.

  Biochemistry 20090310

• Maintenance and growth requirements in the metabolism of Debaryomyces hansenii performing xylose-to-xylitol bioconversion in corncob hemicellulose hydrolyzate.

  Biotechnology and bioengineering 20090301

• Mitochondrial reactive oxygen species are obligatory signals for glucose-induced insulin secretion.

  Diabetes 20090301

• Highly sensitive sensor for detection of NADH based on catalytic growth of Au nanoparticles on glassy carbon electrode.

  Analytical and bioanalytical chemistry 20090301

• Introduction of an NADH regeneration system into Klebsiella oxytoca leads to an enhanced oxidative and reductive metabolism of glycerol.

  Metabolic engineering 20090301

• Thermal aggregation of a model allosteric protein in different conformational states.

  International journal of biological macromolecules 20090301

• Redox responses in yeast to acetate as the carbon source.

  Archives of biochemistry and biophysics 20090301

• Delocalization of nucleolar poly(ADP-ribose) polymerase-1 to the nucleoplasm and its novel link to cellular sensitivity to DNA damage.

  DNA repair 20090301

• Ubiquitous distribution and different subcellular localization of sorbitol dehydrogenase in fruit and leaf of apple.

  Journal of experimental botany 20090301

• Functionalized 3-benzylidene-indolin-2-ones: inducers of NAD(P)H-quinone oxidoreductase 1 (NQO1) with antiproliferative activity.

  Bioorganic & medicinal chemistry 20090301

• Optical detection of glucose by means of metal nanoparticles or semiconductor quantum dots.

  Small (Weinheim an der Bergstrasse, Germany) 20090301

• Antimycin A-induced cell death depends on AIF translocation through NO production and PARP activation and is not involved in ROS generation, cytochrome c release and caspase-3 activation in HL-60 cells.

  The Journal of antibiotics 20090301

• NAD+ and ATP released from injured cells induce P2X7-dependent shedding of CD62L and externalization of phosphatidylserine by murine T cells.

  Journal of immunology (Baltimore, Md. : 1950) 20090301

• Impairment of mitochondrial function by minocycline.

  The FEBS journal 20090301

• Comparison of electropolymerized thiazine dyes as an electrocatalyst in enzymatic biofuel cells and self powered sensors.

  Journal of nanoscience and nanotechnology 20090301

• Primary steps of the Na+-translocating NADH:ubiquinone oxidoreductase catalytic cycle resolved by the ultrafast freeze-quench approach.

  The Journal of biological chemistry 20090227

• Low potential detection of glutamate based on the electrocatalytic oxidation of NADH at thionine/single-walled carbon nanotubes composite modified electrode.

  Biosensors & bioelectronics 20090215

• High expression of thyroid hormone receptors and mitochondrial glycerol-3-phosphate dehydrogenase in the liver is linked to enhanced fatty acid oxidation in Lou/C, a rat strain resistant to obesity.

  The Journal of biological chemistry 20090213

• Engineering of the cofactor specificities and isoform-specific inhibition of malic enzyme.

  The Journal of biological chemistry 20090213

• Damage to cellular and isolated DNA induced by a metabolite of aspirin.

  Mutation research 20090210

• Emerging roles of NAD+ and its metabolites in cell signaling.

  Science signaling 20090210

• High-sensitive glutamate biosensor based on NADH at Lauth's violet/multiwalled carbon nanotubes composite film on gold substrates.

  The journal of physical chemistry. B 20090205

• N-type and P/Q-type calcium channels regulate differentially the release of noradrenaline, ATP and beta-NAD in blood vessels.

  Neuropharmacology 20090201

• Mitochondrial nitrite reduction coupled to soluble guanylate cyclase activation: lack of evidence for a role in the bioactivation of nitroglycerin.

  Nitric oxide : biology and chemistry 20090201

• Identification of an unusual AT(D)Pase-like activity in multifunctional NAD glycohydrolase from the venom of Agkistrodon acutus.

  Biochimie 20090201

• Comparison of the effects of NADH- and NADPH-perturbation stresses on the growth of Escherichia coli.

  Current microbiology 20090201

• Menadione-catalyzed luminol luminescent assay as a novel evaluation method of ethanol tolerance in yeast cells.

  Analytical biochemistry 20090201

• Protective effects of scutellarin against cerebral ischemia in rats: evidence for inhibition of the apoptosis-inducing factor pathway.

  Planta medica 20090201

• Molecular mechanisms of alcoholic fatty liver.

  Alcoholism, clinical and experimental research 20090201

• Attenuation of doxorubicin-induced cardiac injury by mitochondrial glutaredoxin 2.

  Biochimica et biophysica acta 20090201

• Probing stereoselectivity and pro-chirality of hydride transfer during short-chain alcohol dehydrogenase activity: a combined quantitative 2H NMR and computational approach.

  Archives of biochemistry and biophysics 20090201

• Comparison of the nicotinamide catabolism among rat strains.

  Bioscience, biotechnology, and biochemistry 20090201

• Cloning, expression, and characterization of a novel diketoreductase from Acinetobacter baylyi.

  Acta biochimica et biophysica Sinica 20090201

• Enzymatic conversion of atmospheric aldehydes into alcohol in a phospholipid polymer film.

  ACS applied materials & interfaces 20090201

• Biosimulation of drug metabolism--a yeast based model.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090131

• Two-photon autofluorescence microscopy of multicolor excitation.

  Optics letters 20090115

• Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism.

  The Journal of biological chemistry 20090102

• Overexpression of an ADP-ribose pyrophosphatase, AtNUDX2, confers enhanced tolerance to oxidative stress in Arabidopsis plants.

  The Plant journal : for cell and molecular biology 20090101

• Mediator-assisted simultaneous probing of cytosolic and mitochondrial redox activity in living cells.

  Analytical biochemistry 20090101

• Fluorescence spectroscopy as a promising tool for a polyphasic approach to pseudomonad taxonomy.

  Current microbiology 20090101

• The relationship between pyridine nucleotides and seed dormancy.

  The New phytologist 20090101

• Role of NADH/NAD+ transport activity and glycogen store on skeletal muscle energy metabolism during exercise: in silico studies.

  American journal of physiology. Cell physiology 20090101

• A lactate biosensor based on lactate dehydrogenase/nictotinamide adenine dinucleotide (oxidized form) immobilized on a conducting polymer/multiwall carbon nanotube composite film.

  Analytical biochemistry 20090101

• Uapaca genus (Euphorbiaceae), a good source of betulinic acid.

  Fitoterapia 20090101

• Nanoparticle-supported multi-enzyme biocatalysis with in situ cofactor regeneration.

  Journal of biotechnology 20090101

• PARP-1 is involved in autophagy induced by DNA damage.

  Autophagy 20090101

• The mechanisms of oxidative DNA damage and apoptosis induced by norsalsolinol, an endogenous tetrahydroisoquinoline derivative associated with Parkinson's disease.

  Journal of neurochemistry 20090101

• CD38 and CD157 ectoenzymes mark cell subsets in the human corneal limbus.

  Molecular medicine (Cambridge, Mass.) 20090101

• NAD(+)/NADH-sensitive quantum dots: applications to probe NAD(+)-dependent enzymes and to sense the RDX explosive.

  Nano letters 20090101

• Effective quenching processes for physiologically valid metabolite profiling of suspension cultured Mammalian cells.

  Analytical chemistry 20090101

• The role of the invariant glutamate 95 in the catalytic site of Complex I from Escherichia coli.

  Biochimica et biophysica acta 20090101

• Elucidating isoniazid resistance using molecular modeling.

  Journal of chemical information and modeling 20090101

• Transformation and action of extracellular NAD+ in perfused rat and mouse livers.

  Acta pharmacologica Sinica 20090101

• Temperature adaptation of cytosolic malate dehydrogenases of limpets (genus Lottia): differences in stability and function due to minor changes in sequence correlate with biogeographic and vertical distributions.

  The Journal of experimental biology 20090101

• Carbon nanotube-ionic liquid composite sensors and biosensors.

  Analytical chemistry 20090101

• Sensitivity of a glassy carbon electrode covered with a chitin film improved by the addition of carbon powder.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090101

• Barrier compression enhances an enzymatic hydrogen-transfer reaction.

  Angewandte Chemie (International ed. in English) 20090101

• Production of L-malic acid with fixation of HCO3(-) by malic enzyme-catalyzed reaction based on regeneration of coenzyme on electrode modified by layer-by-layer self-assembly method.

  Journal of bioscience and bioengineering 20090101

• Niacin status, NAD distribution and ADP-ribose metabolism.

  Current pharmaceutical design 20090101

• Roles of NAD(+) / NADH and NADP(+) / NADPH in cell death.

  Current pharmaceutical design 20090101

• Nicotinamide phosphoribosyltransferase (Nampt): a link between NAD biology, metabolism, and diseases.

  Current pharmaceutical design 20090101

• NAD in skin: therapeutic approaches for niacin.

  Current pharmaceutical design 20090101

• The importance of NAD in multiple sclerosis.

  Current pharmaceutical design 20090101

• The evolution of schizophrenia: a model for selection by infection, with a focus on NAD.

  Current pharmaceutical design 20090101

• Structures of the multicomponent Rieske non-heme iron toluene 2,3-dioxygenase enzyme system.

  Acta crystallographica. Section D, Biological crystallography 20090101

• Non-sterilized fermentative production of polymer-grade L-lactic acid by a newly isolated thermophilic strain Bacillus sp. 2-6.

  PloS one 20090101

• An unexpected phosphate binding site in glyceraldehyde 3-phosphate dehydrogenase: crystal structures of apo, holo and ternary complex of Cryptosporidium parvum enzyme.

  BMC structural biology 20090101

• Glycerol: an unexpected major metabolite of energy metabolism by the human malaria parasite.

  Malaria journal 20090101

• Therapeutic potential of SIRT1 and NAMPT-mediated NAD biosynthesis in type 2 diabetes.

  Frontiers in bioscience (Landmark edition) 20090101

• Nicotinamide prevents NAD+ depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD+ consumption by SIRT1 may endanger energetically compromised neurons.

  Neuromolecular medicine 20090101

• Hormone-dependent and hormone-independent control of metabolic and developmental functions of malate dehydrogenase - review.

  Endocrine regulations 20090101

• Copper (II) complexes of [1,2,4]triazolo [1,5-a]pyrimidine derivatives as potential anti-parasitic agents.

  Drug metabolism letters 20090101

• NAD and axon degeneration: from the Wlds gene to neurochemistry.

  Cell adhesion & migration 20090101

• SVOP is a nucleotide binding protein.

  PloS one 20090101

• A systematic proteomic study of irradiated DNA repair deficient Nbn-mice.

  PloS one 20090101

• Metabolic impact of redox cofactor perturbations in Saccharomyces cerevisiae.

  Metabolic engineering 20090101

• Menadione reduction by pharmacological doses of ascorbate induces an oxidative stress that kills breast cancer cells.

  International journal of toxicology 20090101

• NAD+ availability and proteotoxicity.

  Neuromolecular medicine 20090101

• A single nutrient feed supports both chemically defined NS0 and CHO fed-batch processes: Improved productivity and lactate metabolism.

  Biotechnology progress 20090101

• The effects of Urtica dioica L. leaf extract on aniline 4-hydroxylase in mice.

  Acta poloniae pharmaceutica 20090101

• Increased OXPHOS activity precedes rise in glycolytic rate in H-RasV12/E1A transformed fibroblasts that develop a Warburg phenotype.

  Molecular cancer 20090101

• Cellular nicotinamide adenine dinucleotide (NADH) as an indicator of bacterial metabolic activity dynamics in activated sludge.

  Water science and technology : a journal of the International Association on Water Pollution Research 20090101

• Structure and function of Plasmodium falciparum malate dehydrogenase: role of critical amino acids in co-substrate binding pocket.

  Biochimie 20090101

• An insight into the role of phosphotransacetylase (pta) and the acetate/acetyl-CoA node in Escherichia coli.

  Microbial cell factories 20090101

• Characterization of the L-lactate dehydrogenase from Aggregatibacter actinomycetemcomitans.

  PloS one 20090101

• Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE.

  PloS one 20090101

• Tandem ChoRE and CCAAT motifs and associated factors regulate Txnip expression in response to glucose or adenosine-containing molecules.

  PloS one 20090101

• Mitochondrial mutations in adenoid cystic carcinoma of the salivary glands.

  PloS one 20090101

• Influence of supplementary vitamins and minerals on lipid peroxidation and redox state in heart, kidney and liver of rats exposed to fluoride.

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20090101

• Glycolytic oscillations in isolated rabbit ventricular myocytes.

  The Journal of biological chemistry 20081226

• Morphological and quantitative study of ganglionated plexus of Calomys callosus trachea.

  Autonomic neuroscience : basic & clinical 20081215

• Tyr-51 is the proton donor-acceptor for NAD(H)-dependent interconversion of xylose and xylitol by Candida tenuis xylose reductase (AKR2B5).

  FEBS letters 20081210

• Theoretical studies of the quinolinic acid to nicotinic acid mononucleotide transformation.

  The Journal of organic chemistry 20081205

• New morphologic and genetic findings in cap disease associated with beta-tropomyosin (TPM2) mutations.

  Neurology 20081202

• Integration of enzyme, strain and reaction engineering to overcome limitations of baker's yeast in the asymmetric reduction of alpha-keto esters.

  Biotechnology and bioengineering 20081201

• Role of residues in the adenosine binding site of NAD of the Ascaris suum malic enzyme.

  Biochimica et biophysica acta 20081201

• Multiple gene-mediated NAD(P)H-dependent aldehyde reduction is a mechanism of in situ detoxification of furfural and 5-hydroxymethylfurfural by Saccharomyces cerevisiae.

  Applied microbiology and biotechnology 20081201

• Separation of flavins and nicotinamide cofactors in Chinese hamster ovary cells by capillary electrophoresis.

  Biomedical chromatography : BMC 20081201

• Crystal structures of Mycobacterium tuberculosis S-adenosyl-L-homocysteine hydrolase in ternary complex with substrate and inhibitors.

  Protein science : a publication of the Protein Society 20081201

• Mechanism of the neuroprotective role of coenzyme Q10 with or without L-dopa in rotenone-induced parkinsonism.

  Neuropharmacology 20081201

• A sensitive NADH and glucose biosensor tuned by visible light based on thionine bridged carbon nanotubes and gold nanoparticles multilayer.

  Biosensors & bioelectronics 20081201

• Changes in pyridine metabolism profile during growth of trigonelline-forming Lotus japonicus cell cultures.

  Phytochemistry 20081201

• The unexplored potential of the pentose phosphate pathway in health and disease.

  Journal of inherited metabolic disease 20081201

• Effect of magnesium ions on the activity of the cytosolic NADH/cytochrome c electron transport system.

  The FEBS journal 20081201

• The expression pattern of NAD(P)H oxidases and the cyclic electron transport pathway around photosystem I of Synechocystis sp. PCC6803 depend on growth conditions.

  Bioscience, biotechnology, and biochemistry 20081201

• Preventing NAD(+) depletion protects neurons against excitotoxicity: bioenergetic effects of mild mitochondrial uncoupling and caloric restriction.

  Annals of the New York Academy of Sciences 20081201

• Antimicrobial action of N-(n-dodecyl)diethanolamine on Escherichia coli: effects on enzymes and growing cultures.

  Journal of applied microbiology 20081201

• Alzheimer's disease, ceramide, visfatin and NAD.

  CNS & neurological disorders drug targets 20081201

• Bioreductive activation of quinone antitumor drugs by mitochondrial voltage-dependent anion channel 1.

  Anatomical science international 20081201

• Highly ordered mesoporous carbons as electrode material for the construction of electrochemical dehydrogenase- and oxidase-based biosensors.

  Biosensors & bioelectronics 20081115

• Electrochemical investigations of the reaction mechanism and kinetics between NADH and redox-active (NC)2C6H3-NHOH/(NC)2C6H3-NO from 4-nitrophthalonitrile-(NC)2C6H3-NO2-modified electrode.

  Biosensors & bioelectronics 20081115

• Defining the in Vivo Role for cytochrome b5 in cytochrome P450 function through the conditional hepatic deletion of microsomal cytochrome b5.

  The Journal of biological chemistry 20081114

• Solar energy in production of L-glutamate through visible light active photocatalyst--redox enzyme coupled bioreactor.

  Chemical communications (Cambridge, England) 20081114

• Inhibitory effects of gallic acid and quercetin on UDP-glucose dehydrogenase activity.

  FEBS letters 20081112

• Sequential electron-transfer and proton-transfer pathways in hydride-transfer reactions from dihydronicotinamide adenine dinucleotide analogues to non-heme oxoiron(IV) complexes and p-chloranil. Detection of radical cations of NADH analogues in acid-promoted hydride-transfer reactions.

  Journal of the American Chemical Society 20081112

• Partially irreversible inactivation of mitochondrial aldehyde dehydrogenase by nitroglycerin.

  The Journal of biological chemistry 20081107

• Engineering cytochrome P450 enzymes for improved activity towards biomimetic 1,4-NADH cofactors.

  Chembiochem : a European journal of chemical biology 20081103

• Vitamin A depletion causes oxidative stress, mitochondrial dysfunction, and PARP-1-dependent energy deprivation.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20081101

• TADH, the thermostable alcohol dehydrogenase from Thermus sp. ATN1: a versatile new biocatalyst for organic synthesis.

  Applied microbiology and biotechnology 20081101

• Characterization of Arabidopsis lines deficient in GAPC-1, a cytosolic NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.

  Plant physiology 20081101

• Tubular aggregate myopathy: a rare form of myopathy.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20081101

• Molecular dynamics simulations of the amyloid-beta binding alcohol dehydrogenase (ABAD) enzyme.

  Bioorganic & medicinal chemistry 20081101

• Replacing Escherichia coli NAD-dependent glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with a NADP-dependent enzyme from Clostridium acetobutylicum facilitates NADPH dependent pathways.

  Metabolic engineering 20081101

• Calcium-dependent activation of mitochondrial metabolism in mammalian cells.

  Methods (San Diego, Calif.) 20081101

• An electrochemical immunosensor using p-aminophenol redox cycling by NADH on a self-assembled monolayer and ferrocene-modified Au electrodes.

  The Analyst 20081101

• Binding of the tautomeric forms of isoniazid-NAD adducts to the active site of the Mycobacterium tuberculosis enoyl-ACP reductase (InhA): a theoretical approach.

  Journal of molecular graphics & modelling 20081101

• Carbon source-dependent modulation of NADP-glutamate dehydrogenases in isophthalate-degrading Pseudomonas aeruginosa strain PP4, Pseudomonas strain PPD and Acinetobacter lwoffii strain ISP4.

  Microbiology (Reading, England) 20081101

• Purification and characterization of cytoplasmic NAD-dependent polypropylene glycol dehydrogenase from Stenotrophomonas maltophilia.

  FEMS microbiology letters 20081101

• Synthesis of 4-pyridoxolactone from pyridoxine using a combination of transformed Escherichia coli cells.

  Journal of bioscience and bioengineering 20081101

• A stopped flow transient kinetic analysis of substrate binding and catalysis in Escherichia coli D-3-phosphoglycerate dehydrogenase.

  The Journal of biological chemistry 20081031

• Orchestration of concurrent oxidation and reduction cycles for stereoinversion and deracemisation of sec-alcohols.

  Journal of the American Chemical Society 20081022

• Weak coupling of ATP hydrolysis to the chemical equilibrium of human nicotinamide phosphoribosyltransferase.

  Biochemistry 20081021

• Covalent and noncovalent intermediates of an NAD utilizing enzyme, human CD38.

  Chemistry & biology 20081020

• Increasing amperometric biosensor sensitivity by length fractionated single-walled carbon nanotubes.

  Biosensors & bioelectronics 20081015

• Time-resolved spectroscopic imaging reveals the fundamentals of cellular NADH fluorescence.

  Optics letters 20081015

• Structural and kinetic properties of a beta-hydroxyacid dehydrogenase involved in nicotinate fermentation.

  Journal of molecular biology 20081010

• Reactive oxygen species production in energized cardiac mitochondria during hypoxia/reoxygenation: modulation by nitric oxide.

  Circulation research 20081010

• Microvascular experimental evidence on the relative significance of restoring oxygen carrying capacity vs. blood viscosity in shock resuscitation.

  Biochimica et biophysica acta 20081001

• Transformation and actions of extracellular NADP(+) in the rat liver.

  Molecular and cellular biochemistry 20081001

• NADH oxidation drives respiratory Na+ transport in mitochondria from Yarrowia lipolytica.

  Archives of microbiology 20081001

• Enzymatic reduction of labile iron by organelles of the rat liver. Superior role of an NADH-dependent activity in the outer mitochondrial membrane.

  Biochimie 20081001

• Activation of ERbeta increases levels of phosphorylated nNOS and NO production through a Src/PI3K/Akt-dependent pathway in hypothalamic neurons.

  Neuropharmacology 20081001

• A cytochrome c containing nitrate reductase plays a role in electron transport for denitrification in Thermus thermophilus without involvement of the bc respiratory complex.

  Molecular microbiology 20081001

• Single sample extraction protocol for the quantification of NAD and NADH redox states in Saccharomyces cerevisiae.

  Journal of separation science 20081001

• Sulphurous mineral water oral therapy: effects on erythrocyte metabolism.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081001

• Pnc1p-mediated nicotinamide clearance modifies the epigenetic properties of rDNA silencing in Saccharomyces cerevisiae.

  Genetics 20081001

• Nucleotide-induced conformational changes in the Escherichia coli NADH:ubiquinone oxidoreductase (complex I).

  Biochemical Society transactions 20081001

• Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle.

  Nature genetics 20081001

• Structure of nicotinic acid mononucleotide adenylyltransferase from Bacillus anthracis.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20081001

• Proton-translocating transhydrogenase: an update of unsolved and controversial issues.

  Journal of bioenergetics and biomembranes 20081001

• The Arabidopsis onset of leaf death5 mutation of quinolinate synthase affects nicotinamide adenine dinucleotide biosynthesis and causes early ageing.

  The Plant cell 20081001

• Chemical and NADH-induced, ROS-dependent, cross-linking between subunits of complex I from Escherichia coli and Thermus thermophilus.

  Biochemistry 20080930

• Direct observation of correlated interdomain motion in alcohol dehydrogenase.

  Physical review letters 20080926

• Plasmodium falciparum Sir2 is an NAD+-dependent deacetylase and an acetyllysine-dependent and acetyllysine-independent NAD+ glycohydrolase.

  Biochemistry 20080923

• A rotor-stator cross-link in the F1-ATPase blocks the rate-limiting step of rotational catalysis.

  The Journal of biological chemistry 20080919

• Early mitochondrial dysfunction in long-lived Mclk1+/- mice.

  The Journal of biological chemistry 20080919

• Incorporation of hydrostatic pressure into models of hydrogen tunneling highlights a role for pressure-modulated promoting vibrations.

  Biochemistry 20080916

• High sensitivity of intestinal CD8+ T cells to nucleotides indicates P2X7 as a regulator for intestinal T cell responses.

  Journal of immunology (Baltimore, Md. : 1950) 20080915

• A SIR-tain acetyl complex is caught by a sulfur trap.

  Structure (London, England : 1993) 20080910

• The crystal structure of seabream antiquitin reveals the structural basis of its substrate specificity.

  FEBS letters 20080903

• Prebiotic origin of glycolytic metabolism: histidine and cysteine can produce acetyl CoA from glucose via reactions homologous to non-phosphorylated Entner-Doudoroff pathway.

  Journal of biochemistry 20080901

• Regulation of pyruvate dehydrogenase in the common killifish, Fundulus heteroclitus, during hypoxia exposure.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080901

• Succinic semialdehyde dehydrogenase from the parasitic cattle tick Rhipicephalus microplus: gene identification, biochemical characterization and comparison with the mouse ortholog.

  Molecular and biochemical parasitology 20080901

• SUGAR-DEPENDENT6 encodes a mitochondrial flavin adenine dinucleotide-dependent glycerol-3-p dehydrogenase, which is required for glycerol catabolism and post germinative seedling growth in Arabidopsis.

  Plant physiology 20080901

• GR24, a synthetic analog of strigolactones, stimulates the mitosis and growth of the arbuscular mycorrhizal fungus Gigaspora rosea by boosting its energy metabolism.

  Plant physiology 20080901

• Biochemical characterization of a mitochondrial-like organelle from Blastocystis sp. subtype 7.

  Microbiology (Reading, England) 20080901

• Characterization of Bacillus halodurans alpha-galactosidase Mel4A encoded by the mel4A gene (BH2228).

  Bioscience, biotechnology, and biochemistry 20080901

• Enzymatic properties of terephthalate 1,2-dioxygenase of Comamonas sp. strain E6.

  Bioscience, biotechnology, and biochemistry 20080901

• Chemometrical examination of active parameters and interactions in flow injection-capillary electrophoresis.

  Electrophoresis 20080901

• Effect of nadcin on energy supply system and apoptosis in ischemia-reperfusion injury to the myocardium.

  Bulletin of experimental biology and medicine 20080901

• Constructing and testing the thermodynamic limits of synthetic NAD(P)H:H2 pathways.

  Microbial biotechnology 20080901

• Structural analysis of the recognition of the negative regulator NmrA and DNA by the zinc finger from the GATA-type transcription factor AreA.

  Journal of molecular biology 20080829

• Solution structure of the integral human membrane protein VDAC-1 in detergent micelles.

  Science (New York, N.Y.) 20080829

• A kinetic alignment of orthologous inosine-5'-monophosphate dehydrogenases.

  Biochemistry 20080819

• Purification and characterization of the epoxidase catalyzing the formation of fosfomycin from Pseudomonas syringae.

  Biochemistry 20080819

• Probing the role of dynamics in hydride transfer catalyzed by lactate dehydrogenase.

  Biophysical journal 20080815

• Crystal structures of the Mycobacterium tuberculosis secretory antigen alanine dehydrogenase (Rv2780) in apo and ternary complex forms captures 'open' and 'closed' enzyme conformations.

  Proteins 20080815

• Metabolic capacity estimation of Escherichia coli as a platform for redox biocatalysis: constraint-based modeling and experimental verification.

  Biotechnology and bioengineering 20080815

• Isomalt production by cloning, purifying and expressing of the MDH gene from Pseudomonas fluorescens DSM 50106 in different strains of E. coli.

  Pakistan journal of biological sciences : PJBS 20080815

• Determination of serum alcohol using a disposable biosensor.

  Forensic science international 20080806

• Multiple RIBEYE-RIBEYE interactions create a dynamic scaffold for the formation of synaptic ribbons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080806

• ERalpha, but not ERbeta, mediates the expression of sexual behavior in the female rat.

  Behavioural brain research 20080805

• Secondary kinetic isotope effects as probes of environmentally-coupled enzymatic hydrogen tunneling reactions.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20080804

• Curcumin downregulates H19 gene transcription in tumor cells.

  Journal of cellular biochemistry 20080801

• Saturation transfer difference NMR studies on substrates and inhibitors of succinic semialdehyde dehydrogenases.

  Biochemical and biophysical research communications 20080801

• Trapping of the thioacylglyceraldehyde-3-phosphate dehydrogenase intermediate from Bacillus stearothermophilus. Direct evidence for a flip-flop mechanism.

  The Journal of biological chemistry 20080801

• Characterization of KlGUT2, a gene of the glycerol-3-phosphate shuttle, in Kluyveromyces lactis.

  FEMS yeast research 20080801

• Direct activation of cytosolic Ca2+ signaling and enzyme secretion by cholecystokinin in human pancreatic acinar cells.

  Gastroenterology 20080801

• Crystal structure of a carbonyl reductase from Candida parapsilosis with anti-Prelog stereospecificity.

  Protein science : a publication of the Protein Society 20080801

• The nature and character of the transition state for the ADP-ribosyltransferase reaction.

  EMBO reports 20080801

• A structural basis for substrate selectivity and stereoselectivity in octopine dehydrogenase from Pecten maximus.

  Journal of molecular biology 20080801

• Multicenter evaluation of a new inosine monophosphate dehydrogenase inhibition assay for quantification of total mycophenolic acid in plasma.

  Therapeutic drug monitoring 20080801

• Expression, purification, crystallization and preliminary X-ray analysis of an NAD-dependent glyceraldehyde-3-phosphate dehydrogenase from Helicobacter pylori.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20080801

• Assay of angiotensin I-converting enzyme-inhibiting activity based on the detection of 3-hydroxybutyrate with water-soluble tetrazolium salt.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20080801

• [Characteristics of endogenous intoxication in children with Helicobacter pylori-associated gastroduodenal diseases].

  Klinicheskaia laboratornaia diagnostika 20080801

• [Heterologous expression of H2O-forming NADH oxidase in Torulopsis glabrata significantly enhance the pyruvate productivity of the host].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20080801

• Molecular clip and tweezer introduce new mechanisms of enzyme inhibition.

  Journal of the American Chemical Society 20080730

• Aromatizing cyclohexa-1,5-diene-1-carbonyl-coenzyme A oxidase. Characterization and its role in anaerobic aromatic metabolism.

  The Journal of biological chemistry 20080725

• The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control.

  Cell 20080725

• Redox state of quinone affects sensitivity of Acanthamoeba castellanii mitochondrial uncoupling protein to purine nucleotides.

  The Biochemical journal 20080715

• Identification and characterization of a bacterial glycerol-1-phosphate dehydrogenase: Ni(2+)-dependent AraM from Bacillus subtilis.

  Biochemistry 20080715

• Determination of pyruvic acid by using enzymic fluorescence capillary analysis.

  Talanta 20080715

• Biosynthesis and recycling of nicotinamide cofactors in mycobacterium tuberculosis. An essential role for NAD in nonreplicating bacilli.

  The Journal of biological chemistry 20080711

• Use of the electrochromic behaviour of lanthanide phthalocyanine films for nicotinamide adenine dinucleotide detection.

  Journal of the Royal Society, Interface 20080706

• Hydride reduction of NAD+ analogues by isopropyl alcohol: kinetics, deuterium isotope effects and mechanism.

  The Journal of organic chemistry 20080704

• Radical scavenging activities of Rio Red grapefruits and Sour orange fruit extracts in different in vitro model systems.

  Bioresource technology 20080701

• NAD(+)-dependent DNA ligase: a novel target waiting for the right inhibitor.

  Medicinal research reviews 20080701

• A calcium influx pathway regulated separately by oxidative stress and ADP-Ribose in TRPM2 channels: single channel events.

  Neurochemical research 20080701

• High-throughput assays for sirtuin enzymes: a microfluidic mobility shift assay and a bioluminescence assay.

  Analytical biochemistry 20080701

• Determination of the cytosolic free NAD/NADH ratio in Saccharomyces cerevisiae under steady-state and highly dynamic conditions.

  Biotechnology and bioengineering 20080701

• Interactions between cell death induced by statins and 7-ketocholesterol in rabbit aorta smooth muscle cells.

  British journal of pharmacology 20080701

• Plant inner membrane anion channel (PIMAC) function in plant mitochondria.

  Plant & cell physiology 20080701

• Design, synthesis, and evaluation of bisubstrate analog inhibitors of cholera toxin.

  Bioorganic & medicinal chemistry letters 20080701

• A shared binding site for NAD+ and coenzyme A in an acetaldehyde dehydrogenase involved in bacterial degradation of aromatic compounds.

  Biochemistry 20080701

• 1.6 angstroms structure of an NAD+-dependent quinate dehydrogenase from Corynebacterium glutamicum.

  Acta crystallographica. Section D, Biological crystallography 20080701

• Partial vinylphenol reductase purification and characterization from Brettanomyces bruxellensis.

  FEMS microbiology letters 20080701

• Electrocatalytic oxidation of dihydronicotineamide adenine dinucleotide on gold electrode modified with catechol-terminated alkanethiol self-assembly.

  Analytica chimica acta 20080630

• Characterization of a benzyl alcohol dehydrogenase from Lactobacillus plantarum WCFS1.

  Journal of agricultural and food chemistry 20080625

• Electrocatalytic oxidation of NADH at gold nanoparticles loaded poly(3,4-ethylenedioxythiophene)-poly(styrene sulfonic acid) film modified electrode and integration of alcohol dehydrogenase for alcohol sensing.

  Talanta 20080615

• Homotropic allosteric control in clostridial glutamate dehydrogenase: different mechanisms for glutamate and NAD+?

  FEBS letters 20080611

• Theory and practice of enzyme bioaffinity electrodes. Chemical, enzymatic, and electrochemical amplification of in situ product detection.

  Journal of the American Chemical Society 20080611

• Structural and biochemical characterization of a novel aldehyde dehydrogenase encoded by the benzoate oxidation pathway in Burkholderia xenovorans LB400.

  Journal of molecular biology 20080606

• Deep tunneling dominates the biologically important hydride transfer reaction from NADH to FMN in morphinone reductase.

  Journal of the American Chemical Society 20080604

• Structural bases for the specific interactions between the E2 and E3 components of the Thermus thermophilus 2-oxo acid dehydrogenase complexes.

  Journal of biochemistry 20080601

• Efficient catalytic turnover of cytochrome P450(cam) is supported by a T252N mutation.

  Archives of biochemistry and biophysics 20080601

• Poly (ADP-ribose) polymerase activity regulates apoptosis in HeLa cells after alkylating DNA damage.

  Cancer biology & therapy 20080601

• The action of extracellular NAD+ in the liver of healthy and tumor-bearing rats: model analysis of the tumor-induced modified response.

  Experimental and molecular pathology 20080601

• Reduced carbohydrate intake in citrin-deficient subjects.

  Journal of inherited metabolic disease 20080601

• Anoxic cell core can promote necrotic cell death in cardiomyocytes at physiological extracellular PO2.

  American journal of physiology. Heart and circulatory physiology 20080601

• Proteomic and metabolomic analyses of the white-rot fungus Phanerochaete chrysosporium exposed to exogenous benzoic acid.

  Journal of proteome research 20080601

• Oxidative stress as a major culprit in kidney disease in diabetes.

  Diabetes 20080601

• Characterization, expression and localization of S-adenosylhomocysteine hydrolase from amphioxus Branchiostoma belcheri tsingtaunese.

  Bioscience reports 20080601

• The succinate:menaquinone reductase of Bacillus cereus: characterization of the membrane-bound and purified enzyme.

  Canadian journal of microbiology 20080601

• Xanthine oxidase-dependent ROS production mediates vitamin A pro-oxidant effects in cultured Sertoli cells.

  Free radical research 20080601

• Xanthine dehydrogenase processes retinol to retinoic acid in human mammary epithelial cells.

  Journal of enzyme inhibition and medicinal chemistry 20080601

• Cytoprotective effects of nicotinamide derivatives in endothelial cells.

  Nucleosides, nucleotides & nucleic acids 20080601

• Mechanism of transition from xanthine dehydrogenase to xanthine oxidase: effect of guanidine-HCL or urea on the activity.

  Nucleosides, nucleotides & nucleic acids 20080601

• NADPH oxidases are involved in differentiation and pathogenicity in Botrytis cinerea.

  Molecular plant-microbe interactions : MPMI 20080601

• [Mutational research on the role of lysine 21 in the Pichia stipitis xylose reductase].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20080601

• Donor dopamine treatment limits pulmonary oedema and inflammation in lung allografts subjected to prolonged hypothermia.

  Transplantation 20080527

• Characterization of the two-component, FAD-dependent monooxygenase SgcC that requires carrier protein-tethered substrates for the biosynthesis of the enediyne antitumor antibiotic C-1027.

  Journal of the American Chemical Society 20080521

• A metabolic throttle regulates the epigenetic state of rDNA.

  Cell 20080516

• Epigenetic control of rDNA loci in response to intracellular energy status.

  Cell 20080516

• Salivary aldehyde dehydrogenase--reversible oxidation of the enzyme and its inhibition by caffeine, investigated using fluorimetric method.

  Archives of oral biology 20080501

• Rapid, stimulation-induced reduction of C12-resorufin in motor nerve terminals: linkage to mitochondrial metabolism.

  Journal of neurochemistry 20080501

• Synthesis and biological evaluation of isosteric analogues of FK866, an inhibitor of NAD salvage.

  ChemMedChem 20080501

• Characterization of dihydrodipicolinate reductase from Thermotoga maritima reveals evolution of substrate binding kinetics.

  Journal of biochemistry 20080501

• Hymenolepis diminuta: mitochondrial transhydrogenase as an additional site for anaerobic phosphorylation.

  Experimental parasitology 20080501

• Glucose 6-phosphate dehydrogenase from larval Taenia crassiceps (cysticerci): purification and properties.

  Parasitology research 20080501

• Flexibility and enzyme activity of NADH oxidase from Thermus thermophilus in the presence of monovalent cations of Hofmeister series.

  Biochimica et biophysica acta 20080501

• Nicorandil and ulcerations: a NAD/NADP and nicotinic acid-dependent side-effect?

  The British journal of dermatology 20080501

• Examination of intrinsic sulfonamide resistance in Bacillus anthracis: a novel assay for dihydropteroate synthase.

  Biochimica et biophysica acta 20080501

• The micro-architecture of the cerebral cortex: functional neuroimaging models and metabolism.

  NeuroImage 20080501

• Structural basis for the NAD-hydrolysis mechanism and the ARTT-loop plasticity of C3 exoenzymes.

  Protein science : a publication of the Protein Society 20080501

• Comparisons of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol activation by human cytochrome P450 and aldo-keto reductase enzymes: effect of redox state and expression levels.

  Chemical research in toxicology 20080501

• The structures of Alcaligenes faecalis D-3-hydroxybutyrate dehydrogenase before and after NAD+ and acetate binding suggest a dynamical reaction mechanism as a member of the SDR family.

  Acta crystallographica. Section D, Biological crystallography 20080501

• Reverse reaction of malic enzyme for HCO3- fixation into pyruvic acid to synthesize L-malic acid with enzymatic coenzyme regeneration.

  Bioscience, biotechnology, and biochemistry 20080501

• Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt.

  Developmental cell 20080501

• Pharmacokinetic aspects of reduced nicotinamide adenine dinucleotide (NADH) in rats.

  Frontiers in bioscience : a journal and virtual library 20080501

• Enzymology of mammalian NAD metabolism in health and disease.

  Frontiers in bioscience : a journal and virtual library 20080501

• One-step versus stepwise mechanism in protonated amino acid-promoted electron-transfer reduction of a quinone by electron donors and two-electron reduction by a dihydronicotinamide adenine dinucleotide analogue. Interplay between electron transfer and hydrogen bonding.

  Journal of the American Chemical Society 20080430

• Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 2. The role of helix 18 stability.

  Biochemistry 20080429

• Spatial patterning of metabolism by mitochondria, oxygen, and energy sinks in a model cytoplasm.

  Current biology : CB 20080422

• Modulation of expression of LDH isoenzymes in endothelial cells by laminin: implications for angiogenesis.

  Journal of cellular biochemistry 20080415

• Non-equivalence of hydrogen transfer from glucose to the pro-R and pro-S methylene positions of ethanol during fermentation by Leuconostoc mesenteroides quantified by 2H NMR at natural abundance.

  The Journal of biological chemistry 20080411

• Purification and partial characterization of Lactobacillus species SK007 lactate dehydrogenase (LDH) catalyzing phenylpyruvic acid (PPA) conversion into phenyllactic acid (PLA).

  Journal of agricultural and food chemistry 20080409

• Three-dimensional structures of apo- and holo-L-alanine dehydrogenase from Mycobacterium tuberculosis reveal conformational changes upon coenzyme binding.

  Journal of molecular biology 20080404

• Synthesis, physicochemical properties and in vitro cytotoxicity of nicotinic acid ester prodrugs intended for pulmonary delivery using perfluorooctyl bromide as vehicle.

  International journal of pharmaceutics 20080402

• Identification by gene deletion analysis of barS2, a gene involved in the biosynthesis of gamma-butyrolactone autoregulator in Streptomyces virginiae.

  Archives of microbiology 20080401

• Expression and characterization of the TNT nitroreductase of Pseudomonas sp. HK-6 in Escherichia coli.

  Current microbiology 20080401

• Reduction of hypervalent states of myoglobin and hemoglobin to their ferrous forms by thymoquinone: the role of GSH, NADH and NADPH.

  Biochimica et biophysica acta 20080401

• NAD depletion by FK866 induces autophagy.

  Autophagy 20080401

• PARP-1 inhibition prevents oxidative and nitrosative stress-induced endothelial cell death via transactivation of the VEGF receptor 2.

  Arteriosclerosis, thrombosis, and vascular biology 20080401

• Crystal structure of enoyl-acyl carrier protein reductase (FabK) from Streptococcus pneumoniae reveals the binding mode of an inhibitor.

  Protein science : a publication of the Protein Society 20080401

• Molecular mechanisms underlying selective cytotoxic activity of BZL101, an extract of Scutellaria barbata, towards breast cancer cells.

  Cancer biology & therapy 20080401

• Cloning and expression of mitochondrial malate dehydrogenase of Clonorchis sinensis.

  Parasitology research 20080401

• NADH- vs NADPH-coupled reduction of 5-hydroxymethyl furfural (HMF) and its implications on product distribution in Saccharomyces cerevisiae.

  Applied microbiology and biotechnology 20080401

• The malate-aspartate NADH shuttle components are novel metabolic longevity regulators required for calorie restriction-mediated life span extension in yeast.

  Genes & development 20080401

• Enzymatic in-capillary derivatization for glucose determination by electrophoresis with spectrophotometric detection.

  Electrophoresis 20080401

• Structure and function of NAD kinase and NADP phosphatase: key enzymes that regulate the intracellular balance of NAD(H) and NADP(H).

  Bioscience, biotechnology, and biochemistry 20080401

• Methotrexate-induced alterations in beta-oxidation correlate with cognitive abilities in children with acute lymphoblastic leukemia.

  Biological research for nursing 20080401

• Purification and characterization of NAD-dependent n-butanol dehydrogenase from solvent-tolerant n-butanol-degrading Enterobacter sp. VKGH12.

  Journal of microbiology and biotechnology 20080401

• Saccharomyces cerevisiae YOR071C encodes the high affinity nicotinamide riboside transporter Nrt1.

  The Journal of biological chemistry 20080328

• Order-disorder-order transitions mediate the activation of cholera toxin.

  Journal of molecular biology 20080328

• Anticancer agent CHS-828 inhibits cellular synthesis of NAD.

  Biochemical and biophysical research communications 20080321

• Isocitrate dehydrogenase: A NADPH-generating enzyme in the lumen of the endoplasmic reticulum.

  Archives of biochemistry and biophysics 20080315

• Benzo[a]pyrene-induced necrosis in the HepG(2) cells via PARP-1 activation and NAD(+) depletion.

  Toxicology 20080312

• Protective effects of 4-amino1,8-napthalimide, a poly (ADP-ribose) polymerase inhibitor in experimental diabetic neuropathy.

  Life sciences 20080312

• Immobilization enzyme fluorescence capillary analysis for determination of lactic acid.

  Analytica chimica acta 20080310

• Characterization of NAD uptake in mammalian cells.

  The Journal of biological chemistry 20080307

• Inosine monophosphate dehydrogenase (IMPDH) as a target in drug discovery.

  Medicinal research reviews 20080301

• Discriminative protection against hydroxyl and superoxide anion radicals by quercetin in human leucocytes in vitro.

  Toxicology in vitro : an international journal published in association with BIBRA 20080301

• Gymnemic acid interacts with mammalian glycerol-3-phosphate dehydrogenase.

  Molecular and cellular biochemistry 20080301

• Characterization of a Listeria monocytogenes protein interfering with Rab5a.

  Traffic (Copenhagen, Denmark) 20080301

• NAD+ and vitamin B3: from metabolism to therapies.

  The Journal of pharmacology and experimental therapeutics 20080301

• Activation of SIRT1, a class III histone deacetylase, contributes to fructose feeding-mediated induction of the alpha-myosin heavy chain expression.

  American journal of physiology. Heart and circulatory physiology 20080301

• Enhancement of coenzyme binding by a single point mutation at the coenzyme binding domain of E. coli lactaldehyde dehydrogenase.

  Protein science : a publication of the Protein Society 20080301

• Identification of an NADH-dependent 5-hydroxymethylfurfural-reducing alcohol dehydrogenase in Saccharomyces cerevisiae.

  Yeast (Chichester, England) 20080301

• NADH dehydrogenase deficiency results in low respiration rate and improved aerobic growth of Zymomonas mobilis.

  Microbiology (Reading, England) 20080301

• Discovery of a ferredoxin:NAD+-oxidoreductase (Rnf) in Acetobacterium woodii: a novel potential coupling site in acetogens.

  Annals of the New York Academy of Sciences 20080301

• [The spectrum studies of mechano-optical signal transduction with participation of LDH].

  Guang pu xue yu guang pu fen xi = Guang pu 20080301

• Substrate orientation in xanthine oxidase: crystal structure of enzyme in reaction with 2-hydroxy-6-methylpurine.

  The Journal of biological chemistry 20080222

• Particle-tethered NADH for production of methanol from CO(2) catalyzed by coimmobilized enzymes.

  Biotechnology and bioengineering 20080215

• Niacin restriction upregulates NADPH oxidase and reactive oxygen species (ROS) in human keratinocytes.

  Free radical biology & medicine 20080215

• Redox-cycling compounds can cause the permeabilization of mitochondrial membranes by mechanisms other than ROS production.

  Free radical biology & medicine 20080215

• Iromycins from Streptomyces sp. and from synthesis: new inhibitors of the mitochondrial electron transport chain.

  Bioorganic & medicinal chemistry 20080215

• Structure of 2-deoxy-scyllo-inosose synthase, a key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics, in complex with a mechanism-based inhibitor and NAD+.

  Proteins 20080201

• The pharmacokinetics, toxicities, and biologic effects of FK866, a nicotinamide adenine dinucleotide biosynthesis inhibitor.

  Investigational new drugs 20080201

• Energy metabolism, altered proteins, sirtuins and ageing: converging mechanisms?

  Biogerontology 20080201

• Regular oscillatory behavior of aqueous solutions of CuII salts related to effects on equilibrium dynamics of ortho/para hydrogen spin isomers of water.

  Journal of inorganic biochemistry 20080201

• Inhibition of agouti-related peptide expression by glucose in a clonal hypothalamic neuronal cell line is mediated by glycolysis, not oxidative phosphorylation.

  Endocrinology 20080201

• NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences.

  Antioxidants & redox signaling 20080201

• Genetic and biochemical characterization of a 4-hydroxybenzoate hydroxylase from Corynebacterium glutamicum.

  Applied microbiology and biotechnology 20080201

• Effects of nicotinamide adenine dinucleotide hydride on physical and mental performance.

  Journal of sports sciences 20080201

• Hippocampal mitochondrial dysfunction in rat aging.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080201

• Catalase as a source of both X- and V-factor for Haemophilus influenzae.

  FEMS microbiology letters 20080201

• UPLC-ESI-TOFMS-based metabolomics and gene expression dynamics inspector self-organizing metabolomic maps as tools for understanding the cellular response to ionizing radiation.

  Analytical chemistry 20080201

• Bifunctional NMN adenylyltransferase/ADP-ribose pyrophosphatase: structure and function in bacterial NAD metabolism.

  Structure (London, England : 1993) 20080201

• Sequence analysis of ribosomal and mitochondrial genes of the giant liver fluke Fascioloides magna (Trematoda: Fasciolidae): intraspecific variation and differentiation from Fasciola hepatica.

  The Journal of parasitology 20080201

• Accelerated utilization of lactate under the effect of hypoxen after intensive exercise.

  Bulletin of experimental biology and medicine 20080201

• The role of tryptophan metabolism in iNOS transcription and nitric oxide production by chicken macrophage cells upon treatment with interferon gamma.

  Immunology letters 20080129

• Structure-guided engineering of the coenzyme specificity of Pseudomonas fluorescens mannitol 2-dehydrogenase to enable efficient utilization of NAD(H) and NADP(H).

  FEBS letters 20080123

• High rates of superoxide production in skeletal-muscle mitochondria respiring on both complex I- and complex II-linked substrates.

  The Biochemical journal 20080115

• Kinetic model for Ca2+-induced permeability transition in energized liver mitochondria discriminates between inhibitor mechanisms.

  The Journal of biological chemistry 20080111

• Biochemical and structural characterization of a novel family of cystathionine beta-synthase domain proteins fused to a Zn ribbon-like domain.

  Journal of molecular biology 20080104

• Structure and quantum chemical analysis of NAD+-dependent isocitrate dehydrogenase: hydride transfer and co-factor specificity.

  Proteins 20080101

• In vitro studies indicate a quinone is involved in bacterial Mn(II) oxidation.

  Archives of microbiology 20080101

• Protective effect of Amomi semen extract on alloxan-induced pancreatic beta-cell damage.

  Phytotherapy research : PTR 20080101

• Transformation products of extracellular NAD(+) in the rat liver: kinetics of formation and metabolic action.

  Molecular and cellular biochemistry 20080101

• Acetaldehyde addition throughout the growth phase alleviates the phenotypic effect of zinc deficiency in Saccharomyces cerevisiae.

  Applied microbiology and biotechnology 20080101

• Cloning, expression, purification, and characterization of AmphiTip30, a member of short-chain dehydrogenases/reductases family from the amphioxus Branchiostoma belcheri tsingtauense.

  Protein expression and purification 20080101

• The role of amino acids T148 and R281 in human dihydrolipoamide dehydrogenase.

  Journal of biomedical science 20080101

• Archaeal alcohol dehydrogenase active at increased temperatures and in the presence of organic solvents.

  Applied microbiology and biotechnology 20080101

• Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice.

  Aging cell 20080101

• Azoreductase and dye detoxification activities of Bacillus velezensis strain AB.

  Applied microbiology and biotechnology 20080101

• Nicotinate riboside salvage in plants: presence of nicotinate riboside kinase in mungbean seedlings.

  Plant physiology and biochemistry : PPB 20080101

• Effect of polyphenol-containing azuki bean (Vigna angularis) extract on blood pressure elevation and macrophage infiltration in the heart and kidney of spontaneously hypertensive rats.

  Clinical and experimental pharmacology & physiology 20080101

• Effectiveness of phenoxyl radicals generated by peroxidase/H2O2-catalyzed oxidation of caffeate, ferulate, and p-coumarate in cooxidation of ascorbate and NADH.

  Journal of plant research 20080101

• Response surface examination of the relationship between experimental conditions and product distribution in electrophoretically mediated microanalysis.

  Electrophoresis 20080101

• Analysis of the respiratory chain in Ethanologenic Zymomonas mobilis with a cyanide-resistant bd-type ubiquinol oxidase as the only terminal oxidase and its possible physiological roles.

  Journal of molecular microbiology and biotechnology 20080101

• Detection of a radical cation of an NADH analogue in two-electron reduction of a protonated p-quinone derivative by an NADH analogue.

  Angewandte Chemie (International ed. in English) 20080101

• Modeling the electron transport chain of purple non-sulfur bacteria.

  Molecular systems biology 20080101

• The prediction of the hepatic clearance of tanshinone IIA in rat liver subcellular fractions: accuracy improvement.

  Current drug metabolism 20080101

• Identification of a subunit of NADH-dehydrogenase as a p49/STRAP-binding protein.

  BMC cell biology 20080101

• Structural studies on flavohemoglobins.

  Methods in enzymology 20080101

• Characterization of NAD-dependent malate dehydrogenases from spinach leaves.

  Protoplasma 20080101

• Effect of alternate energy substrates on mammalian brain metabolism during ischemic events.

  Advances in experimental medicine and biology 20080101

• The role of NAD+ depletion in the mechanism of sulfur mustard-induced metabolic injury.

  Cutaneous and ocular toxicology 20080101

• Nicotinamide adenine dinucleotide based therapeutics.

  Current medicinal chemistry 20080101

• Inhibitors of NAD+ dependent histone deacetylases (sirtuins).

  Current pharmaceutical design 20080101

• Structure, function, and mechanism of cytosolic quinone reductases.

  Vitamins and hormones 20080101

• Development of a new bioprocess for production of 1,3-propanediol I.: Modeling of glycerol bioconversion to 1,3-propanediol with Klebsiella pneumoniae enzymes.

  Applied biochemistry and biotechnology 20080101

• Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition.

  Annual review of nutrition 20080101

• The Mycobacterium tuberculosis Rv2540c DNA sequence encodes a bifunctional chorismate synthase.

  BMC biochemistry 20080101

• Mechanisms underlying the loss of mitochondrial membrane potential in glutamate excitotoxicity.

  Biochimica et biophysica acta 20080101

• Pharmacological inhibition of nicotinamide phosphoribosyltransferase/visfatin enzymatic activity identifies a new inflammatory pathway linked to NAD.

  PloS one 20080101

• Sites of generation of reactive oxygen species in homogenates of brain tissue determined with the use of respiratory substrates and inhibitors.

  Biochimica et biophysica acta 20080101

• H2O2 generation is decreased by calcium in isolated brain mitochondria.

  Biochimica et biophysica acta 20080101

• Metabolism of nicotinamide, adenine and inosine in developing microspore-derived canola (Brassica napus) embryos.

  Plant physiology and biochemistry : PPB 20080101

• Diversification of myco-heterotrophic angiosperms: evidence from Burmanniaceae.

  BMC evolutionary biology 20080101

• Frequency domain fluorometry with pulsed light-emitting diodes.

  Annals of the New York Academy of Sciences 20080101

• A novel strategy involved in [corrected] anti-oxidative defense: the conversion of NADH into NADPH by a metabolic network.

  PloS one 20080101

• Pancreatic beta-cell purification by altering FAD and NAD(P)H metabolism.

  Experimental diabetes research 20080101

• Glucose metabolism is accelerated by exposure to t-butylhydroperoxide during NADH consumption in human erythrocytes.

  Blood cells, molecules & diseases 20080101

• Reactive oxygen species generation through NADH oxidation by pterin derivatives.

  Nucleic acids symposium series (2004) 20080101

• Metabolic dynamics in skeletal muscle during acute reduction in blood flow and oxygen supply to mitochondria: in-silico studies using a multi-scale, top-down integrated model.

  PloS one 20080101

• A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+ biosynthetic gene BNA2 in chromosome end protection.

  Genome biology 20080101

• Total synthesis and biological activity of neopeltolide and analogues.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Synthesis and electrochemical reduction of a ruthenium complex bearing an N,N-Bis[(benzo[g][1,5]naphthyridin-2-yl)methyl]propane-2-amine ligand as an NAD+/NADH-type redox site.

  Angewandte Chemie (International ed. in English) 20080101

• Electrochemical detection of blood alcohol concentration using a disposable biosensor based on screen-printed electrode modified with Nafion and gold nanoparticles.

  Clinical chemistry and laboratory medicine 20080101

• Reduced nicotinamide adenine dinucleotide fluorescence lifetime separates human mesenchymal stem cells from differentiated progenies.

  Journal of biomedical optics 20080101

• High resolution contrast ultrasound and NADH fluorescence imaging of myocardial perfusion in excised rat hearts.

  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20080101

• [Transamination in the mechanism of protection of mitochondria from Ca2+ overload].

  Biomeditsinskaia khimiia 20080101

• Flow cytometric quantification of glucose-stimulated beta-cell metabolic flux can reveal impaired islet functional potency.

  Cell transplantation 20080101

• Comparing flux balance analysis to network expansion: producibility, sustainability and the scope of compounds.

  Genome informatics. International Conference on Genome Informatics 20080101

• S-nitrosation of mitochondrial complex I depends on its structural conformation.

  The Journal of biological chemistry 20071228

• Syntheses of nicotinamide riboside and derivatives: effective agents for increasing nicotinamide adenine dinucleotide concentrations in mammalian cells.

  Journal of medicinal chemistry 20071227

• Reversible dissociation of flavin mononucleotide from the mammalian membrane-bound NADH: ubiquinone oxidoreductase (complex I).

  FEBS letters 20071222

• Pyruvate-sensitive AOX exists as a non-covalently associated dimer in the homeothermic spadix of the skunk cabbage, Symplocarpus renifolius.

  FEBS letters 20071222

• Stereocomplementary bioreduction of alpha,beta-unsaturated dicarboxylic acids and dimethyl esters using enoate reductases: enzyme- and substrate-based stereocontrol.

  Organic letters 20071220

• Multiple roles of arginine 181 in binding and catalysis in the NAD-malic enzyme from Ascaris suum.

  Biochemistry 20071218

• Colorimetric quantification of alpha-D-galactose 1-phosphate.

  Analytical biochemistry 20071215

• Enzymatic assay of D-serine using D-serine dehydratase from Saccharomyces cerevisiae.

  Analytical biochemistry 20071215

• A pneumococcal MerR-like regulator and S-nitrosoglutathione reductase are required for systemic virulence.

  The Journal of infectious diseases 20071215

• Carbon nanofiber vs. carbon microparticles as modifiers of glassy carbon and gold electrodes applied in electrochemical sensing of NADH.

  Talanta 20071215

• Manufacture and evaluation of carbon nanotube modified screen-printed electrodes as electrochemical tools.

  Talanta 20071215

• Nornicotine-organocatalyzed aqueous reduction of alpha,beta-unsaturated aldehydes.

  Chemical communications (Cambridge, England) 20071214

• Transhydrogenation reactions catalyzed by mitochondrial NADH-ubiquinone oxidoreductase (Complex I).

  Biochemistry 20071211

• Induction of the NAD(P)H:quinone oxidoreductase 1 by ketoconazole and itraconazole: a mechanism of cancer chemoprotection.

  Cancer letters 20071208

• Understanding nicotinamide dinucleotide cofactor and substrate specificity in class I flavoprotein disulfide oxidoreductases: crystallographic analysis of a glutathione amide reductase.

  Journal of molecular biology 20071207

• Consideration of molecular arrangements in regio- and enantioselective reduction of an NAD model compound controlled by carbonyl oxygen orientation.

  Organic & biomolecular chemistry 20071207

• Biotransformation of D-methionine into L-methionine in the cascade of four enzymes.

  Biotechnology and bioengineering 20071201

• Tryptophan, adenosine, neurodegeneration and neuroprotection.

  Metabolic brain disease 20071201

• The antiviral drug ribavirin is a selective inhibitor of S-adenosyl-L-homocysteine hydrolase from Trypanosoma cruzi.

  Bioorganic & medicinal chemistry 20071201

• Uncoupling is without an effect on the production of reactive oxygen species by in situ synaptic mitochondria.

  Journal of neurochemistry 20071201

• Growth rate of a non-fermentative Escherichia coli strain is influenced by NAD+ regeneration.

  Biotechnology letters 20071201

• Putative reaction mechanism of heterologously expressed octopine dehydrogenase from the great scallop, Pecten maximus (L).

  The FEBS journal 20071201

• The thuggacins, novel antibacterial macrolides from Sorangium cellulosum acting against selected Gram-positive bacteria.

  The Journal of antibiotics 20071201

• NAD kinases use substrate-assisted catalysis for specific recognition of NAD.

  The Journal of biological chemistry 20071123

• Mechanism of proton transfer in the 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni.

  The Journal of biological chemistry 20071123

• Integrating glutathione metabolism and mitochondrial dysfunction with implications for Parkinson's disease: a dynamic model.

  Neuroscience 20071123

• Differences among cell types in NAD(+) compartmentalization: a comparison of neurons, astrocytes, and cardiac myocytes.

  Journal of neuroscience research 20071115

• Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analogues.

  Journal of medicinal chemistry 20071115

• Flavone as PARP-1 inhibitor: its effect on lipopolysaccharide induced gene-expression.

  European journal of pharmacology 20071114

• Mutagenesis of morphinone reductase induces multiple reactive configurations and identifies potential ambiguity in kinetic analysis of enzyme tunneling mechanisms.

  Journal of the American Chemical Society 20071114

• Association and redox properties of the putidaredoxin reductase-nicotinamide adenine dinucleotide complex.

  Biochemistry 20071113

• Role of NAD binding and catalytic residues in the C-terminal binding protein corepressor.

  FEBS letters 20071113

• Ubiquitin-mediated degradation of Rpn4 is controlled by a phosphorylation-dependent ubiquitylation signal.

  Biochimica et biophysica acta 20071101

• New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose.

  Neurochemical research 20071101

• D-mannitol production by resting state whole cell biotrans-formation of D-fructose by heterologous mannitol and formate dehydrogenase gene expression in Bacillus megaterium.

  Biotechnology journal 20071101

• Membrane-bound L- and D-lactate dehydrogenase activities of a newly isolated Pseudomonas stutzeri strain.

  Applied microbiology and biotechnology 20071101

• Adaptation of muscle fibre types and capillary network to acute denervation and shortlasting reinnervation.

  Cell and tissue research 20071101

• Plasmodium falciparum Sir2: an unusual sirtuin with dual histone deacetylase and ADP-ribosyltransferase activity.

  Eukaryotic cell 20071101

• Evidence from ESI-MS for NQO1-catalyzed reduction of estrogen ortho-quinones.

  Free radical biology & medicine 20071101

• Visualizing extracellular matrix and sensing fibroblasts metabolism in human dermis by nonlinear spectral imaging.

  Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 20071101

• Synthesis and biological evaluation of new 2-arylcarbonyl-3-trifluoromethylquinoxaline 1,4-di-N-oxide derivatives and their reduced analogues.

  Journal of medicinal chemistry 20071101

• Isolation and characterization of a benzoylformate decarboxylase and a NAD+/NADP+-dependent benzaldehyde dehydrogenase involved in D-phenylglycine metabolism in Pseudomonas stutzeri ST-201.

  Biochimica et biophysica acta 20071101

• Transport and metabolism of L-lactate occur in mitochondria from cerebellar granule cells and are modified in cells undergoing low potassium dependent apoptosis.

  Biochimica et biophysica acta 20071101

• Cosubstrate-induced dynamics of D-3-hydroxybutyrate dehydrogenase from Pseudomonas putida.

  The FEBS journal 20071101

• Autofluorescence properties of rat liver under hypermetabolic conditions.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20071101

• Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme.

  Cell metabolism 20071101

• Structural studies of the final enzyme in the alpha-aminoadipate pathway-saccharopine dehydrogenase from Saccharomyces cerevisiae.

  Journal of molecular biology 20071026

• An assessment of the role of intracellular reductive capacity in the biological clearance of triarylmethane dyes.

  Journal of hazardous materials 20071022

• Synthesis of 6-formylpterin nucleoside analogs and their ROS generation activities in the presence of NADH in the dark.

  Organic & biomolecular chemistry 20071021

• Copper ions inhibit S-adenosylhomocysteine hydrolase by causing dissociation of NAD+ cofactor.

  Biochemistry 20071016

• Infrared multiphoton dissociation and electron-induced dissociation as alternative MS/MS strategies for metabolite identification.

  Analytical chemistry 20071015

• N-lysine propionylation controls the activity of propionyl-CoA synthetase.

  The Journal of biological chemistry 20071012

• Enzymatic characterization of dihydrolipoamide dehydrogenase from Streptococcus pneumoniae harboring its own substrate.

  The Journal of biological chemistry 20071005

• Structure-activity studies on suramin analogues as inhibitors of NAD+-dependent histone deacetylases (sirtuins).

  ChemMedChem 20071001

• Transcriptionally regulated adhA gene encodes alcohol dehydrogenase required for ethanol and n-propanol utilization in Corynebacterium glutamicum R.

  Applied microbiology and biotechnology 20071001

• Uptake and reduction of alpha-lipoic acid by human erythrocytes.

  Clinical biochemistry 20071001

• Predicting the binding properties of cibacron blue F3GA in affinity separation systems.

  International journal of biological macromolecules 20071001

• Assimilation of NAD(+) precursors in Candida glabrata.

  Molecular microbiology 20071001

• Dietary flavones and flavonoles are inhibitors of poly(ADP-ribose)polymerase-1 in pulmonary epithelial cells.

  The Journal of nutrition 20071001

• The differential effects of superoxide anion, hydrogen peroxide and hydroxyl radical on cardiac mitochondrial oxidative phosphorylation.

  Free radical research 20071001

• Different effects of monocarboxylates on neuronal survival and beta-amyloid toxicity.

  The European journal of neuroscience 20071001

• The alternative reading frame tumor suppressor antagonizes hypoxia-induced cancer cell migration via interaction with the COOH-terminal binding protein corepressor.

  Cancer research 20071001

• Nicotinamide riboside kinase structures reveal new pathways to NAD+.

  PLoS biology 20071001

• Functional analysis of type 1 isopentenyl diphosphate isomerase from Halobacterium sp. NRC-1.

  Bioscience, biotechnology, and biochemistry 20071001

• Characterization of ligV essential for catabolism of vanillin by Sphingomonas paucimobilis SYK-6.

  Bioscience, biotechnology, and biochemistry 20071001

• Geographical variation in populations of Phlebotomus (Paraphlebotomus) caucasicus (Diptera: Psychodidae) in Iran.

  Bulletin de la Societe de pathologie exotique (1990) 20071001

• Mathematical modelling of NADH oxidation catalyzed by new NADH oxidase from Lactobacillus brevis in continuously operated enzyme membrane reactor.

  Journal of bioscience and bioengineering 20071001

• Mutation of Tyr-218 to Phe in Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase: effects on bioelectronic interface performance.

  Applied biochemistry and biotechnology 20071001

• Redox-dependent change of nucleotide affinity to the active site of the mammalian complex I.

  Biochemistry 20070925

• Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival.

  Cell 20070921

• Catalytic activity of iron hexacyanoosmate(II) towards hydrogen peroxide and nicotinamide adenine dinucleotide and its use in amperometric biosensors.

  Analytica chimica acta 20070919

• NADH photo-oxidation is enhanced by a partially purified lambda-crystallin fraction from rabbit lens.

  Molecular vision 20070918

• On the road to bacterial cell death.

  Cell 20070907

• A common mechanism of cellular death induced by bactericidal antibiotics.

  Cell 20070907

• An equation-free approach to analyzing heterogeneous cell population dynamics.

  Journal of mathematical biology 20070901

• Lactate dehydrogenase undergoes a substantial structural change to bind its substrate.

  Biophysical journal 20070901

• Characterization of malate dehydrogenase from the hyperthermophilic archaeon Pyrobaculum islandicum.

  Extremophiles : life under extreme conditions 20070901

• Expression of glf Z.m. increases D-mannitol formation in whole cell biotransformation with resting cells of Corynebacterium glutamicum.

  Applied microbiology and biotechnology 20070901

• NADPH production by the pentose phosphate pathway in the zona fasciculata of rat adrenal gland.

  The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20070901

• On-line measurements of oscillating mitochondrial membrane potential in glucose-fermenting Saccharomyces cerevisiae.

  Yeast (Chichester, England) 20070901

• Crystallographic studies on the binding of isonicotinyl-NAD adduct to wild-type and isoniazid resistant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis.

  Journal of structural biology 20070901

• Catalase-1 (CAT-1) and nucleoside diphosphate kinase-1 (NDK-1) play an important role in protecting conidial viability under light stress in Neurospora crassa.

  Molecular genetics and genomics : MGG 20070901

• Optimized carbon nanotube fiber microelectrodes as potential analytical tools.

  Analytical and bioanalytical chemistry 20070901

• AtNUDT7, a negative regulator of basal immunity in Arabidopsis, modulates two distinct defense response pathways and is involved in maintaining redox homeostasis.

  Plant physiology 20070901

• 11Beta-hydroxysteroid dehydrogenase enzymes in the testis and male reproductive tract of the boar (Sus scrofa domestica) indicate local roles for glucocorticoids in male reproductive physiology.

  Reproduction (Cambridge, England) 20070901

• Ethanol production from xylose by recombinant Saccharomyces cerevisiae expressing protein-engineered NADH-preferring xylose reductase from Pichia stipitis.

  Microbiology (Reading, England) 20070901

• A comparative proteomic approach to understand the adaptations of an H+ -ATPase-defective mutant of Corynebacterium glutamicum ATCC14067 to energy deficiencies.

  Proteomics 20070901

• Electrophoretically mediated microanalysis of a nicotinamide adenine dinucleotide-dependent enzyme and its facile multiplexing using an active pixel sensor UV detector.

  Journal of chromatography. A 20070831

• Mechanism of GlvA from Bacillus subtilis: a detailed kinetic analysis of a 6-phospho-alpha-glucosidase from glycoside hydrolase family 4.

  Biochemistry 20070828

• Elevation of cellular NAD levels by nicotinic acid and involvement of nicotinic acid phosphoribosyltransferase in human cells.

  The Journal of biological chemistry 20070824

• Effects of relative hypoglycemia on LTP and NADH imaging in rat hippocampal slices.

  Brain research 20070824

• Mechanistic implications of the cysteine-nicotinamide adduct in aldehyde dehydrogenase based on quantum mechanical/molecular mechanical simulations.

  Biochemistry 20070821

• Modification of substrate specificity in single point mutants of Agrobacterium tumefaciens type II NADH dehydrogenase.

  FEBS letters 20070821

• Zinc irreversibly damages major enzymes of energy production and antioxidant defense prior to mitochondrial permeability transition.

  The Journal of biological chemistry 20070817

• NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.

  The Biochemical journal 20070815

• Neuroglobin and cytoglobin as potential enzyme or substrate.

  Gene 20070815

• Synthesis of 4-phenoxybenzamide adenine dinucleotide as NAD analogue with inhibitory activity against enoyl-ACP reductase (InhA) of Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20070815

• NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs.

  Oncogene 20070813

• Rv1106c from Mycobacterium tuberculosis is a 3beta-hydroxysteroid dehydrogenase.

  Biochemistry 20070807

• Why do some yeast species require niacin for growth? Different modes of NAD synthesis.

  FEMS yeast research 20070801

• NADH oxidase activity of rat and human liver xanthine oxidoreductase: potential role in superoxide production.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070801

• Shortage of lipid-radical cycles in membranes as a possible prime cause of energetic failure in aging and Alzheimer disease.

  Neurochemical research 20070801

• Oxidation of butane to butanol coupled to electrochemical redox reaction of NAD+/NADH.

  Biotechnology letters 20070801

• Nicotinamidase activity is important for germination.

  The Plant journal : for cell and molecular biology 20070801

• Purification and characterization of aldehyde dehydrogenase with a broad substrate specificity originated from 2-phenylethanol-assimilating Brevibacterium sp. KU1309.

  Applied microbiology and biotechnology 20070801

• Crystal structure of archaeal highly thermostable L-aspartate dehydrogenase/NAD/citrate ternary complex.

  The FEBS journal 20070801

• 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces oxidative stress, DNA strand breaks, and poly(ADP-ribose) polymerase-1 activation in human breast carcinoma cell lines.

  Toxicology letters 20070801

• Computational study of glyceraldehyde-3-phosphate dehydrogenase of Entamoeba histolytica: implications for structure-based drug design.

  Journal of biomolecular structure & dynamics 20070801

• The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis.

  Immunity 20070801

• Insights from modeling the 3D structure of NAD(P)H-dependent D-xylose reductase of Pichia stipitis and its binding interactions with NAD and NADP.

  Biochemical and biophysical research communications 20070727

• Characterization and mechanistic studies of type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase from Staphylococcus aureus.

  Biochemistry 20070717

• Mitochondria, ciglitazone and liver: a neglected interaction in biochemical pharmacology.

  European journal of pharmacology 20070712

• Nitrite-driven anaerobic ATP synthesis in barley and rice root mitochondria.

  Planta 20070701

• The guinea-pig is a poor animal model for studies of niacin deficiency and presents challenges in any study using purified diets.

  The British journal of nutrition 20070701

• Activation of biliverdin-IXalpha reductase by inorganic phosphate and related anions.

  The Biochemical journal 20070701

• Acetaldehyde mediates growth stimulation of ethanol-stressed Saccharomyces cerevisiae: evidence of a redox-driven mechanism.

  Biotechnology letters 20070701

• NAD-dependent isocitrate dehydrogenase mutants of Arabidopsis suggest the enzyme is not limiting for nitrogen assimilation.

  Plant physiology 20070701

• A high-throughput assay for the adenylation reaction of bacterial DNA ligase.

  Analytical biochemistry 20070701

• Pyridine nucleotide redox abnormalities in diabetes.

  Antioxidants & redox signaling 20070701

• Xanthomonas caspase displays an inherent PARP-like activity.

  FEMS microbiology letters 20070701

• A novel ferric reductase purified from Magnetospirillum gryphiswaldense MSR-1.

  Current microbiology 20070701

• Biochemical and functional characterization of UDP-galactose 4-epimerase from Aeromonas hydrophila.

  Biochimica et biophysica acta 20070701

• Degradation kinetics of caffeine and related methylxanthines by induced cells of Pseudomonas sp.

  Current microbiology 20070701

• Biochemical characterization of enoyl reductase involved in Type II fatty acid synthesis in the intestinal coccidium Eimeria tenella (Phylum Apicomplexa).

  FEMS microbiology letters 20070701

• Acceleration of ethanol and acetaldehyde oxidation by D-glycerate in rats.

  Metabolism: clinical and experimental 20070701

• NAD+ released during inflammation participates in T cell homeostasis by inducing ART2-mediated death of naive T cells in vivo.

  Journal of immunology (Baltimore, Md. : 1950) 20070701

• Studies on estrogen receptor (ER) alpha and beta responses on gene regulation in peripheral blood leukocytes in vivo using selective ER agonists.

  The Journal of endocrinology 20070701

• Estrogen inhibition of norepinephrine responsiveness is initiated at the plasma membrane of GnRH-producing GT1-7 cells.

  The Journal of endocrinology 20070701

• nadA and nadB of Shigella flexneri 5a are antivirulence loci responsible for the synthesis of quinolinate, a small molecule inhibitor of Shigella pathogenicity.

  Microbiology (Reading, England) 20070701

• Analysis of the NADH-dependent retinaldehyde reductase activity of amphioxus retinol dehydrogenase enzymes enhances our understanding of the evolution of the retinol dehydrogenase family.

  The FEBS journal 20070701

• Cloning of four genes involved in limonene hydroxylation from Enterobacter cowanii 6L.

  Journal of microbiology and biotechnology 20070701

• Collaborator of Stat6 (CoaSt6)-associated poly(ADP-ribose) polymerase activity modulates Stat6-dependent gene transcription.

  The Journal of biological chemistry 20070629

• Determinants of substrate specificity for saccharopine dehydrogenase from Saccharomyces cerevisiae.

  Biochemistry 20070626

• Amperometric biosensor based on Prussian Blue-modified screen-printed electrode for lipase activity and triacylglycerol determination.

  Analytica chimica acta 20070626

• Baicalein impairs vascular tone in normal rat aortas: role of superoxide anions.

  European journal of pharmacology 20070622

• Renewable dehydrogenase-based interfaces for bioelectronic applications.

  Langmuir : the ACS journal of surfaces and colloids 20070619

• Amperometric ethanol biosensor based on poly(vinyl alcohol)-multiwalled carbon nanotube-alcohol dehydrogenase biocomposite.

  Biosensors & bioelectronics 20070615

• Catalytic mechanism of Zn2+-dependent polyol dehydrogenases: kinetic comparison of sheep liver sorbitol dehydrogenase with wild-type and Glu154-->Cys forms of yeast xylitol dehydrogenase.

  The Biochemical journal 20070615

• Temperature preconditioning of isolated rat hearts--a potent cardioprotective mechanism involving a reduction in oxidative stress and inhibition of the mitochondrial permeability transition pore.

  The Journal of physiology 20070615

• In vitro RNA editing in plant mitochondria does not require added energy.

  FEBS letters 20070612

• Iron-sulfur cluster N7 of the NADH:ubiquinone oxidoreductase (complex I) is essential for stability but not involved in electron transfer.

  Biochemistry 20070605

• Poly(ADP-ribose) polymerase inhibition by cilostazol is implicated in the neuroprotective effect against focal cerebral ischemic infarct in rat.

  Brain research 20070604

• Poly(ADP-ribose) polymerase-1 protects neurons against apoptosis induced by oxidative stress.

  Cell death and differentiation 20070601

• Methylenebis(sulfonamide) linked nicotinamide adenine dinucleotide analogue as an inosine monophosphate dehydrogenase inhibitor.

  Bioorganic & medicinal chemistry letters 20070601

• Mutational analysis of NADH-binding residues in triphenylmethane reductase from Citrobacter sp. strain KCTC 18061P.

  FEMS microbiology letters 20070601

• Enzymatic properties of the lactate dehydrogenase enzyme from Plasmodium falciparum.

  The FEBS journal 20070601

• Enantioselective oxidation of trans-4-hydroxy-2-nonenal is aldehyde dehydrogenase isozyme and Mg2+ dependent.

  Chemical research in toxicology 20070601

• Biochemical characterization and phylogenetic analysis based on 16S rRNA sequences for V-factor dependent members of Pasteurellaceae derived from laboratory rats.

  Current microbiology 20070601

• Feasibility analysis of an epidermal glucose sensor based on time-resolved fluorescence.

  Applied optics 20070601

• A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin.

  Experimental dermatology 20070601

• High-resolution structures of formate dehydrogenase from Candida boidinii.

  Protein science : a publication of the Protein Society 20070601

• Irradiation of GAPDH: a model for environmentally induced protein damage.

  Biological chemistry 20070601

• Fabrication and characterization of Meldola's blue/zinc oxide hybrid electrodes for efficient detection of the reduced form of nicotinamide adenine dinucleotide at low potential.

  Analytica chimica acta 20070529

• Sirt1 regulates aging and resistance to oxidative stress in the heart.

  Circulation research 20070525

• Laser photoexcitation of NAD(P)H induces reduction of P450 BM3 heme domain on the microsecond time scale.

  Journal of the American Chemical Society 20070523

• Evidence from Raman spectroscopy that InhA, the mycobacterial enoyl reductase, modulates the conformation of the NADH cofactor to promote catalysis.

  Journal of the American Chemical Society 20070523

• Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 1. Basic features of the association and dissociation processes.

  Biochemistry 20070515

• An improved biosensor for acetaldehyde determination using a bienzymatic strategy at poly(neutral red) modified carbon film electrodes.

  Analytica chimica acta 20070515

• Sir2 deacetylases exhibit nucleophilic participation of acetyl-lysine in NAD+ cleavage.

  Journal of the American Chemical Society 20070509

• Structural evidence for a ligand coordination switch in liver alcohol dehydrogenase.

  Biochemistry 20070508

• Role of alpha-Asp181, beta-Asp192, and gamma-Asp190 in the distinctive subunits of human NAD-specific isocitrate dehydrogenase.

  Biochemistry 20070508

• Vitamins and aging: pathways to NAD+ synthesis.

  Cell 20070504

• Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+.

  Cell 20070504

• Biochemical characterization of isocitrate dehydrogenase from Methylococcus capsulatus reveals a unique NAD+-dependent homotetrameric enzyme.

  Archives of microbiology 20070501

• Endothelial cell response to lactate: implication of PAR modification of VEGF.

  Journal of cellular physiology 20070501

• Over-expression, purification, and characterization of recombinant NAD-malic enzyme from Escherichia coli K12.

  Protein expression and purification 20070501

• Anaerobic glycerol production by Saccharomyces cerevisiae strains under hyperosmotic stress.

  Applied microbiology and biotechnology 20070501

• Recruitment of NADH shuttling in pressure-overloaded and hypertrophic rat hearts.

  American journal of physiology. Cell physiology 20070501

• Role of microsomal retinol/sterol dehydrogenase-like short-chain dehydrogenases/reductases in the oxidation and epimerization of 3alpha-hydroxysteroids in human tissues.

  Endocrinology 20070501

• Modulation of vascular reactivity in normal, hypertensive and diabetic rat aortae by a non-antioxidant flavonoid.

  Pharmacological research 20070501

• Decavanadate induces mitochondrial membrane depolarization and inhibits oxygen consumption.

  Journal of inorganic biochemistry 20070501

• Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery.

  Expert opinion on therapeutic targets 20070501

• 11beta-Hydroxysteroid dehydrogenase expression and activities in bovine granulosa cells and corpora lutea implicate corticosteroids in bovine ovarian physiology.

  The Journal of endocrinology 20070501

• An azoreductase, aerobic NADH-dependent flavoprotein discovered from Bacillus sp.: functional expression and enzymatic characterization.

  Applied microbiology and biotechnology 20070501

• Crystallization of human nicotinamide phosphoribosyltransferase.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20070501

• [Regulation mechanism of the intercellular redox status involved in the response to environmental stress in higher plants].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20070501

• ADP-ribosylation activity in pertussis vaccines and its relationship to the in vivo histamine-sensitisation test.

  Vaccine 20070430

• In vivo and in vitro analyses of single-amino acid variants of the Salmonella enterica phosphotransacetylase enzyme provide insights into the function of its N-terminal domain.

  The Journal of biological chemistry 20070427

• Arachidonic acid promotes glutamate-induced cell death associated with necrosis by 12- lipoxygenase activation in glioma cells.

  Life sciences 20070424

• Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis.

  Biochemistry 20070424

• A novel branched-chain amino acid metabolon. Protein-protein interactions in a supramolecular complex.

  The Journal of biological chemistry 20070420

• SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress.

  Genes & development 20070415

• A reductase-mimicking thiourea organocatalyst incorporating a covalently bound NADH analogue: efficient 1,2-diketone reduction with in situ prosthetic group generation and recycling.

  Chemical communications (Cambridge, England) 20070414

• Extension of human cell lifespan by nicotinamide phosphoribosyltransferase.

  The Journal of biological chemistry 20070413

• Determination of various alcohols based on a new immobilized enzyme fluorescence capillary analysis.

  Analytica chimica acta 20070404

• Nicotinamide 2-fluoroadenine dinucleotide unmasks the NAD+ glycohydrolase activity of Aplysia californica adenosine 5'-diphosphate ribosyl cyclase.

  Biochemistry 20070403

• Systemic pyruvate administration markedly reduces infarcts and motor deficits in rat models of transient and permanent focal cerebral ischemia.

  Neurobiology of disease 20070401

• Adulteration of mustard cooking oil with argemone oil: do Indian food regulatory policies and antioxidant therapy both need revisitation?

  Antioxidants & redox signaling 20070401

• A plate reader method for the measurement of NAD, NADP, glutathione, and ascorbate in tissue extracts: Application to redox profiling during Arabidopsis rosette development.

  Analytical biochemistry 20070401

• Histochemical staining and quantification of dihydrolipoamide dehydrogenase diaphorase activity using blue native PAGE.

  Electrophoresis 20070401

• Parameters affecting the chemical work output of a hybrid photoelectrochemical biofuel cell.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20070401

• Fatty acid synthase inhibition activates AMP-activated protein kinase in SKOV3 human ovarian cancer cells.

  Cancer research 20070401

• Integrated rate equation considering product inhibition and its application to kinetic assay of serum ethanol.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20070401

• Pharmacological targeting of IDO-mediated tolerance for treating autoimmune disease.

  Current drug metabolism 20070401

• Photosensitized DNA damage induced by NADH: site specificity and mechanism.

  Free radical research 20070401

• Preliminary report of NAD+-dependent amino acid dehydrogenase producing bacteria isolated from soil.

  Iranian biomedical journal 20070401

• Ability of carbazole salts, inhibitors of Alzheimer beta-amyloid fibril formation, to cross cellular membranes.

  European journal of pharmacology 20070322

• Structures of the dI2dIII1 complex of proton-translocating transhydrogenase with bound, inactive analogues of NADH and NADPH reveal active site geometries.

  Biochemistry 20070320

• The flavoprotein subcomplex of complex I (NADH:ubiquinone oxidoreductase) from bovine heart mitochondria: insights into the mechanisms of NADH oxidation and NAD+ reduction from protein film voltammetry.

  Biochemistry 20070320

• Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity.

  The Biochemical journal 20070315

• Role of glycolysis inhibition and poly(ADP-ribose) polymerase activation in necrotic-like cell death caused by ascorbate/menadione-induced oxidative stress in K562 human chronic myelogenous leukemic cells.

  International journal of cancer 20070315

• Parallel activation of mitochondrial oxidative metabolism with increased cardiac energy expenditure is not dependent on fatty acid oxidation in pigs.

  The Journal of physiology 20070315

• Stimulation-induced changes in NADH fluorescence and mitochondrial membrane potential in lizard motor nerve terminals.

  The Journal of physiology 20070315

• Probing binding requirements of NAD kinase with modified substrate (NAD) analogues.

  Bioorganic & medicinal chemistry letters 20070315

• Coimmobilization of dehydrogenases and their cofactors in electrochemical biosensors.

  Analytical chemistry 20070315

• Biosynthesis of thiamin thiazole in eukaryotes: conversion of NAD to an advanced intermediate.

  Journal of the American Chemical Society 20070314

• Identification of Candida tenuis xylose reductase as highly selective biocatalyst for the synthesis of aromatic alpha-hydroxy esters and improvement of its efficiency by protein engineering.

  Chemical communications (Cambridge, England) 20070314

• An in vitro study on metabolism of 17beta-boldenone and boldione using cattle liver and kidney subcellular fractions.

  Analytica chimica acta 20070314

• Hypothyroidism provides resistance to kidney mitochondria against the injury induced by renal ischemia-reperfusion.

  Life sciences 20070313

• N-methyl-(R)-3-(tert-butyl)-sulfinyl-1,4-dihydropyridine: a novel NADH model compound.

  Molecules (Basel, Switzerland) 20070312

• Altered poly(ADP-ribose) metabolism impairs cellular responses to genotoxic stress in a hypomorphic mutant of poly(ADP-ribose) glycohydrolase.

  Experimental cell research 20070310

• Ca2+ Activation kinetics of the two aspartate-glutamate mitochondrial carriers, aralar and citrin: role in the heart malate-aspartate NADH shuttle.

  The Journal of biological chemistry 20070309

• Roles of bound quinone in the single subunit NADH-quinone oxidoreductase (Ndi1) from Saccharomyces cerevisiae.

  The Journal of biological chemistry 20070302

• Crystal structure of D-erythronate-4-phosphate dehydrogenase complexed with NAD.

  Journal of molecular biology 20070302

• Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation.

  Neuroscience 20070302

• Damage of oxidative stress on mitochondria during microspores development in Honglian CMS line of rice.

  Plant cell reports 20070301

• Utilization of hydrophobic bacterium Rhodococcus opacus B-4 as whole-cell catalyst in anhydrous organic solvents.

  Applied microbiology and biotechnology 20070301

• Kinetic characterization of inosine monophosphate dehydrogenase of Leishmania donovani.

  Molecular and biochemical parasitology 20070301

• Up-regulation of plasma membrane-associated redox activities in neuronal cells lacking functional mitochondria.

  Journal of neurochemistry 20070301

• The regulation of nicotinamide adenine dinucleotide biosynthesis by Nampt/PBEF/visfatin in mammals.

  Current opinion in gastroenterology 20070301

• The power to reduce: pyridine nucleotides--small molecules with a multitude of functions.

  The Biochemical journal 20070301

• Biochemical characterization of TASSELSEED 2, an essential plant short-chain dehydrogenase/reductase with broad spectrum activities.

  The FEBS journal 20070301

• Synechocystis DrgA protein functioning as nitroreductase and ferric reductase is capable of catalyzing the Fenton reaction.

  The FEBS journal 20070301

• Lot6p from Saccharomyces cerevisiae is a FMN-dependent reductase with a potential role in quinone detoxification.

  The FEBS journal 20070301

• Studies of Toxoplasma gondii and Plasmodium falciparum enoyl acyl carrier protein reductase and implications for the development of antiparasitic agents.

  Acta crystallographica. Section D, Biological crystallography 20070301

• The involvement of ATP produced via (ADP-Ribose)n in the maintenance of DNA replication apparatus during DNA repair.

  Biological & pharmaceutical bulletin 20070301

• Nicotinamidase participates in the salvage pathway of NAD biosynthesis in Arabidopsis.

  The Plant journal : for cell and molecular biology 20070301

• Role of Gts1p in regulation of energy-metabolism oscillation in continuous cultures of the yeast Saccharomyces cerevisiae.

  Yeast (Chichester, England) 20070301

• Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin.

  Structure (London, England : 1993) 20070301

• Dietary protein level and dietary interaction affect quinolinic acid concentration in rats.

  International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20070301

• Reactive oxygen species generation through NADH oxidation by 6-formylpterin derivatives in the dark.

  Biochemical and biophysical research communications 20070223

• Quantitative continuous assay for hyaluronan synthase.

  Analytical biochemistry 20070215

• Distinct modes of recognition of the lipoyl domain as substrate by the E1 and E3 components of the pyruvate dehydrogenase multienzyme complex.

  Journal of molecular biology 20070209

• Pyruvate improves recovery after PARP-1-associated energy failure induced by oxidative stress in neonatal rat cerebrocortical slices.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070201

• A mathematical model of the mitochondrial NADH shuttles and anaplerosis in the pancreatic beta-cell.

  American journal of physiology. Endocrinology and metabolism 20070201

• Changes in mitochondrial electron transport chain activity during insect metamorphosis.

  American journal of physiology. Regulatory, integrative and comparative physiology 20070201

• Inactivation of lactate dehydrogenase by several chemicals: implications for in vitro toxicology studies.

  Toxicology in vitro : an international journal published in association with BIBRA 20070201

• Enhanced activity of 3alpha-hydroxysteroid dehydrogenase by addition of the co-solvent 1-butyl-3-methylimidazolium (L)-lactate in aqueous phase of biphasic systems for reductive production of steroids.

  Journal of biotechnology 20070201

• Electron transfer from NADH bound to horse liver alcohol dehydrogenase (NAD+ dependent dehydrogenase): visualisation of the activity in the enzyme crystals and adsorption of formazan derivatives by these crystals.

  Bioorganic chemistry 20070201

• Kinetics of electron transfer from NADH to the Escherichia coli nitric oxide reductase flavorubredoxin.

  The FEBS journal 20070201

• Regulation of redox metabolism in the mouse oocyte and embryo.

  Development (Cambridge, England) 20070201

• NADH screen-printed electrodes modified with zirconium phosphate, Meldola blue, and Reinecke salt. Application to the detection of glycerol by FIA.

  Analytical and bioanalytical chemistry 20070201

• Effect of FPS1 deletion on the fermentation properties of Saccharomyces cerevisiae.

  Letters in applied microbiology 20070201

• Cell surface oxygen consumption: a major contributor to cellular oxygen consumption in glycolytic cancer cell lines.

  Biochimica et biophysica acta 20070201

• Arabidopsis thaliana nicotinate/nicotinamide mononucleotide adenyltransferase (AtNMNAT) is required for pollen tube growth.

  The Plant journal : for cell and molecular biology 20070201

• Molecular characterization of the membrane-bound quinol peroxidase functionally connected to the respiratory chain.

  The FEBS journal 20070201

• Nonenzymatic reduction of thymoquinone in physiological conditions.

  Free radical research 20070201

• Comparison of basis set effects and the performance of ab initio and DFT methods for probing equilibrium fluctuations.

  Journal of computational chemistry 20070130

• Temperature-dependent structure of the E x S complex of Bacillus stearothermophilus alcohol dehydrogenase.

  Biochemistry 20070123

• Mechanism of thioamide drug action against tuberculosis and leprosy.

  The Journal of experimental medicine 20070122

• A probe for NADH and H2O2 amperometric detection at low applied potential for oxidase and dehydrogenase based biosensor applications.

  Biosensors & bioelectronics 20070115

• New competitive inhibitors of cytosolic (NADH-dependent) rabbit muscle glycerophosphate dehydrogenase.

  Bioorganic & medicinal chemistry letters 20070115

• Metabolite transport across the peroxisomal membrane.

  The Biochemical journal 20070115

• HIV-1 trans activator of transcription protein elicits mitochondrial hyperpolarization and respiratory deficit, with dysregulation of complex IV and nicotinamide adenine dinucleotide homeostasis in cortical neurons.

  Journal of immunology (Baltimore, Md. : 1950) 20070115

• Detection of NADH and ethanol based on catalytic activity of soluble carbon nanofiber with low overpotential.

  Analytical chemistry 20070115

• NAD(+) and axon degeneration revisited: Nmnat1 cannot substitute for Wld(S) to delay Wallerian degeneration.

  Cell death and differentiation 20070101

• Moderate dependence of ROS formation on DeltaPsim in isolated brain mitochondria supported by NADH-linked substrates.

  Neurochemical research 20070101

• Purification, characterization and cloning of aldehyde dehydrogenase from Rhodococcus erythropolis UPV-1.

  Applied microbiology and biotechnology 20070101

• Redistribution of carbon flux in Torulopsis glabrata by altering vitamin and calcium level.

  Metabolic engineering 20070101

• Inhibition of aldehyde detoxification in CNS mitochondria by fungicides.

  Neurotoxicology 20070101

• In search for new antipsoriatic agents: NAD topical composition.

  Skin pharmacology and physiology 20070101

• Neither energy collapse nor transcription underlie in vitro neurotoxicity of poly(ADP-ribose) polymerase hyper-activation.

  Neurochemistry international 20070101

• Dihydrolipoyl dehydrogenase as a source of reactive oxygen species inhibited by caloric restriction and involved in Saccharomyces cerevisiae aging.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070101

• Mitochondrial function in liver disease.

  Frontiers in bioscience : a journal and virtual library 20070101

• NAD+ and NADH in brain functions, brain diseases and brain aging.

  Frontiers in bioscience : a journal and virtual library 20070101

• Tissue kallikrein protects against pressure overload-induced cardiac hypertrophy through kinin B2 receptor and glycogen synthase kinase-3beta activation.

  Cardiovascular research 20070101

• NAD+ metabolism in health and disease.

  Trends in biochemical sciences 20070101

• Temperature dependence for fluorescence of beta-NADH in glycerol/water solution and in trehalose/sucrose glass.

  Journal of fluorescence 20070101

• Unique properties of NADP-thioredoxin reductase C in legumes.

  Journal of experimental botany 20070101

• Electrode surface confinement of self-assembled enzyme aggregates using magnetic nanoparticles and its application in bioelectrocatalysis.

  Analytical chemistry 20070101

• Electrochemical regeneration of NADH using conductive vanadia-silica xerogels.

  Biotechnology progress 20070101

• Preparation of novel silica-coated alginate gel beads for efficient encapsulation of yeast alcohol dehydrogenase.

  Journal of biomaterials science. Polymer edition 20070101

• Mitochondrial permeability transition relevance for apoptotic triggering in the post-ischemic heart.

  The international journal of biochemistry & cell biology 20070101

• [Features of the toxic action of 2,4,6-trinitrotoluene on Escherichia coli K12].

  Prikladnaia biokhimiia i mikrobiologiia 20070101

• [Kinetics of Ca2+, NADH, and oxidized flavoproteins in the frog olfactory lining under the effect of odorants].

  Biofizika 20070101

• Determination of the lactose content of fluid milk by spectrophotometric enzymatic analysis using weight additions and path length adjustment: collaborative study.

  Journal of AOAC International 20070101

• No association between Helicobacter pylori seropositivity and ornithine decarboxylase (ODC) A317G polymorphism, and no modification by NAD(P)H:qinone oxidoreductase 1 (NQO1) C609T.

  Nagoya journal of medical science 20070101

• [Properties of NAD-dependent brain enzymes under the conditions of hypoxia and ischemia].

  Vestnik Rossiiskoi akademii meditsinskikh nauk 20070101

• Niacin deficiency alters p53 expression and impairs etoposide-induced cell cycle arrest and apoptosis in rat bone marrow cells.

  Nutrition and cancer 20070101

• ECTO-NOX target for the anticancer isoflavene phenoxodiol.

  Oncology research 20070101

• Cytotoxic activity of the selected pyridinium salts against murine leukemia L1210.

  Pharmacological reports : PR 20070101

• Metabolic flux elucidation for large-scale models using 13C labeled isotopes.

  Metabolic engineering 20070101

• Effects of the deletion of the Escherichia coli frataxin homologue CyaY on the respiratory NADH:ubiquinone oxidoreductase.

  BMC biochemistry 20070101

• Cyclic ADP-ribose as a universal calcium signal molecule in the nervous system.

  Neurochemistry international 20070101

• The tricarboxylic acid cycle, an ancient metabolic network with a novel twist.

  PloS one 20070101

• Elementary mode analysis to study the preculturing effect on the metabolic state of Lactobacillus rhamnosus during growth on mixed substrates.

  In silico biology 20070101

• Enzymes involved in DNA ligation and end-healing in the radioresistant bacterium Deinococcus radiodurans.

  BMC molecular biology 20070101

• Improving the purification of NAD+-dependent formate dehydrogenase from Candida methylica.

  Preparative biochemistry & biotechnology 20070101

• [Metabolic changes of lymphocytes and neoplastic cells in mice with Ehrlich ascites carcinoma during tumor growth].

  Izvestiia Akademii nauk. Seriia biologicheskaia 20070101

• Experimental study on predicting skin flap necrosis by fluorescence in the FAD and NADH bands during surgery.

  Photochemistry and photobiology 20070101

• [Detection of C-P-lyase activity in a cell-free extract of Escherichia coli].

  Prikladnaia biokhimiia i mikrobiologiia 20070101

• [Characteristic metabolic disturbances in the rat tissues caused by long-term use of alcohol].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20070101

• Influence of electromagnetic radiation on enzyme kinetics.

  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20070101

• Attempting to remove the substrate inhibition of L-lactate dehydrogenase from Bacillus stearothermophilus by site-directed mutagenesis.

  Applied biochemistry and biotechnology 20070101

• Fluoroquinolone antibiotics having the potential to interfere with fluorescence-based diagnosis.

  Photochemistry and photobiology 20070101

• Chemical natures of 6-formylpterin nucleoside analogs.

  Nucleic acids symposium series (2004) 20070101

• [Hybrid Mn-peroxidases from basidiomycetes: a review].

  Prikladnaia biokhimiia i mikrobiologiia 20070101

• The NADH oxidase-Prx system in Amphibacillus xylanus.

  Sub-cellular biochemistry 20070101

• Methods to determine the status of mitochondrial ATP synthase assembly.

  Methods in molecular biology (Clifton, N.J.) 20070101

• Thermodynamics and kinetics of the glyoxylate cycle.

  Biochemistry 20061226

• Carbon nanotubes-polymer-redox mediator hybrid thin film for electrocatalytic sensing.

  Biosensors & bioelectronics 20061215

• Inactivation of copper, zinc superoxide dismutase by H2O2 : mechanism of protection.

  Free radical biology & medicine 20061215

• Evolution of enzymatic activities in the enolase superfamily: D-tartrate dehydratase from Bradyrhizobium japonicum.

  Biochemistry 20061212

• Fluorescent DNA base replacements: Reporters and sensors for biological systems.

  Organic & biomolecular chemistry 20061207

• A single mutation at Tyr143 of human S-adenosylhomocysteine hydrolase renders the enzyme thermosensitive and affects the oxidation state of bound cofactor nicotinamide-adenine dinucleotide.

  The Biochemical journal 20061201

• Xylitol dehydrogenase from Candida tropicalis: molecular cloning of the gene and structural analysis of the protein.

  Applied microbiology and biotechnology 20061201

• Orthric Rieske dioxygenases for degrading mixtures of 2,4-dinitrotoluene/naphthalene and 2-amino-4,6-dinitrotoluene/4-amino-2,6-dinitrotoluene.

  Applied microbiology and biotechnology 20061201

• A kinetic study on the lactoperoxidase catalyzed oxidation of estrogens.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20061201

• The 2'-phosphate of NADP is responsible for proper orientation of the nicotinamide ring in the oxidative decarboxylation reaction catalyzed by sheep liver 6-phosphogluconate dehydrogenase.

  The Journal of biological chemistry 20061201

• A role for copper in biological time-keeping.

  Journal of inorganic biochemistry 20061201

• Peroxisomal membrane permeability and solute transfer.

  Biochimica et biophysica acta 20061201

• Determination of adenine and pyridine nucleotides in glucose-limited chemostat cultures of Penicillium simplicissimum by one-step ethanol extraction and ion-pairing liquid chromatography.

  Analytical biochemistry 20061201

• Mechanisms of action of isoniazid.

  Molecular microbiology 20061201

• Influences of reactive oxygen species and nitric oxide on hepatic fibrogenesis.

  Liver international : official journal of the International Association for the Study of the Liver 20061201

• Transient and partial mitochondrial inhibition for the treatment of postresuscitation injury: getting it just right.

  Critical care medicine 20061201

• Contribution of calcium influx in mediating glucose-stimulated oxygen consumption in pancreatic islets.

  Diabetes 20061201

• Protective effects of the PARP-1 inhibitor PJ34 in hypoxic-reoxygenated cardiomyoblasts.

  Cellular and molecular life sciences : CMLS 20061201

• Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity.

  PLoS biology 20061201

• Engineering NADH metabolism in Saccharomyces cerevisiae: formate as an electron donor for glycerol production by anaerobic, glucose-limited chemostat cultures.

  FEMS yeast research 20061201

• Configuration of a scintillation proximity assay for the activity assessment of recombinant human adenine phosphoribosyltransferase.

  Assay and drug development technologies 20061201

• Characterization of catalytic properties of hydrogenase isolated from the unicellular cyanobacterium Gloeocapsa alpicola CALU 743.

  Biochemistry. Biokhimiia 20061201

• NAD metabolism and sirtuins: metabolic regulation of protein deacetylation in stress and toxicity.

  The AAPS journal 20061201

• Catalytic asymmetric transfer hydrogenation of alpha-ketoesters with hantzsch esters.

  Organic letters 20061123

• A mechanistic dichotomy in scandium ion-promoted hydride transfer of an NADH analogue: delicate balance between one-step hydride-transfer and electron-transfer pathways.

  Journal of the American Chemical Society 20061122

• Biochemical basis of 4-hydroxyanisole induced cell toxicity towards B16-F0 melanoma cells.

  Cancer letters 20061118

• Identification of a novel NADH-specific aldo-keto reductase using sequence and structural homologies.

  The Biochemical journal 20061115

• Structure of a NADH-insensitive hexameric citrate synthase that resists acid inactivation.

  Biochemistry 20061114

• Neuroprotective effects of NU1025, a PARP inhibitor in cerebral ischemia are mediated through reduction in NAD depletion and DNA fragmentation.

  Life sciences 20061110

• Reduction of mitomycin C is catalysed by human recombinant NRH:quinone oxidoreductase 2 using reduced nicotinamide adenine dinucleotide as an electron donating co-factor.

  British journal of cancer 20061106

• Calcium-dependent modulation of poly(ADP-ribose) polymerase-1 alters cellular metabolism and DNA repair.

  The Journal of biological chemistry 20061103

• Glutamine-dependent NAD+ synthetase. How a two-domain, three-substrate enzyme avoids waste.

  The Journal of biological chemistry 20061103

• Binding mode analysis of the NADH cofactor in nitric oxide reductase: a theoretical study.

  Journal of molecular graphics & modelling 20061101

• Enhancement of pyruvate productivity in Torulopsis glabrata: Increase of NAD+ availability.

  Journal of biotechnology 20061101

• Physiological and genetic engineering of cytosolic redox metabolism in Saccharomyces cerevisiae for improved glycerol production.

  Metabolic engineering 20061101

• Role of energetic coenzyme pools in the production of L-carnitine by Escherichia coli.

  Metabolic engineering 20061101

• Inactivation of aldehyde dehydrogenase: a key factor for engineering 1,3-propanediol production by Klebsiella pneumoniae.

  Metabolic engineering 20061101

• FCCP is cardioprotective at concentrations that cause mitochondrial oxidation without detectable depolarisation.

  Cardiovascular research 20061101

• 2-Deoxy-D-glucose reduces epilepsy progression by NRSF-CtBP-dependent metabolic regulation of chromatin structure.

  Nature neuroscience 20061101

• Sensing cell metabolism by time-resolved autofluorescence.

  Optics letters 20061101

• The importance of redox shuttles to pancreatic beta-cell energy metabolism and function.

  Biochemical Society transactions 20061101

• Alpha-secondary isotope effects as probes of 'tunneling-ready' configurations in enzymatic H-tunneling: insight from environmentally coupled tunneling models.

  Journal of the American Chemical Society 20061101

• NAD+-induced vasotoxicity in the pericyte-containing microvasculature of the rat retina: effect of diabetes.

  Investigative ophthalmology & visual science 20061101

• Inhibiting glycolysis to reduce seizures: how it might work.

  Nature neuroscience 20061101

• Nicotinamide adenine dinucleotide staining immediately following radio frequency ablation of renal tumors-is a positive stain synonymous with ablative failure?

  The Journal of urology 20061101

• Elevated lactate suppresses neuronal firing in vivo and inhibits glucose metabolism in hippocampal slice cultures.

  Brain research 20061030

• Dissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase.

  The Journal of biological chemistry 20061027

• Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis.

  The Journal of biological chemistry 20061027

• Elementary steps of enzymatic oxidation of nifedipine catalyzed by horseradish peroxidase.

  The journal of physical chemistry. B 20061026

• Extracellular NAD+ is an agonist of the human P2Y11 purinergic receptor in human granulocytes.

  The Journal of biological chemistry 20061020

• Extracellular NAD+ metabolism modulates osteoclastogenesis.

  Biochemical and biophysical research communications 20061020

• Direct demonstration of an adaptive constraint.

  Science (New York, N.Y.) 20061020

• Mechanism for lactate-color stabilization in injection-enhanced beef.

  Journal of agricultural and food chemistry 20061004

• Redesign of Schistosoma mansoni NAD+ catabolizing enzyme: active site H103W mutation restores ADP-ribosyl cyclase activity.

  Biochemistry 20061003

• Overall kinetic mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae.

  Biochemistry 20061003

• Biodegradation of phthalate isomers by Pseudomonas aeruginosa PP4, Pseudomonas sp. PPD and Acinetobacter lwoffii ISP4.

  Applied microbiology and biotechnology 20061001

• Regulation of mouse hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme in the tryptophan-nicotinamide adenine dinucleotide pathway, by hepatocyte nuclear factor 4alpha and peroxisome proliferator-activated receptor alpha.

  Molecular pharmacology 20061001

• Role of glutamine 148 of human 15-hydroxyprostaglandin dehydrogenase in catalytic oxidation of prostaglandin E2.

  Bioorganic & medicinal chemistry 20061001

• Expression and characterization of the assimilatory NADH-nitrite reductase from the phototrophic bacterium Rhodobacter capsulatus E1F1.

  Archives of microbiology 20061001

• A family of killer toxins. Exploring the mechanism of ADP-ribosylating toxins.

  The FEBS journal 20061001

• Tyrosine-dependent oxidative DNA damage induced by carcinogenic tetranitromethane.

  Chemical research in toxicology 20061001

• Zinc neurotoxicity is dependent on intracellular NAD levels and the sirtuin pathway.

  The European journal of neuroscience 20061001

• [Characterization of hydrogen peroxide production by a novel oral streptococci, S. oligofermentans isolated from human oral cavity].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20061001

• Sevoflurane modulates the activity of glyceraldehyde 3-phosphate dehydrogenase.

  Journal of enzyme inhibition and medicinal chemistry 20061001

• Caffeine metabolites are inhibitors of the nuclear enzyme poly(ADP-ribose)polymerase-1 at physiological concentrations.

  Biochemical pharmacology 20060928

• Modulation by homocysteine of the iberiotoxin-sensitive, Ca2+ -activated K+ channels of porcine coronary artery smooth muscle cells.

  European journal of pharmacology 20060928

• Biosynthesis of fosfomycin, re-examination and re-confirmation of a unique Fe(II)- and NAD(P)H-dependent epoxidation reaction.

  Biochemistry 20060926

• Ligand-induced conformational changes in the capping subdomain of a bacterial old yellow enzyme homologue and conserved sequence fingerprints provide new insights into substrate binding.

  The Journal of biological chemistry 20060922

• ATP regulation in adult rat cardiomyocytes: time-resolved decoding of rapid mitochondrial calcium spiking imaged with targeted photoproteins.

  The Journal of biological chemistry 20060922

• Crystal structure of Thermus thermophilus Delta1-pyrroline-5-carboxylate dehydrogenase.

  Journal of molecular biology 20060922

• Staurosporine and rebeccamycin aglycones are assembled by the oxidative action of StaP, StaC, and RebC on chromopyrrolic acid.

  Journal of the American Chemical Society 20060920

• Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060920

• Structural insights into the function of the thiamin biosynthetic enzyme Thi4 from Saccharomyces cerevisiae.

  Biochemistry 20060919

• Electrochemical biosensor based on integrated assembly of dehydrogenase enzymes and gold nanoparticles.

  Analytical chemistry 20060915

• A transverse tubule NADPH oxidase activity stimulates calcium release from isolated triads via ryanodine receptor type 1 S -glutathionylation.

  The Journal of biological chemistry 20060908

• SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells.

  Cell 20060908

• Redirection of the NADH oxidation pathway in Torulopsis glabrata leads to an enhanced pyruvate production.

  Applied microbiology and biotechnology 20060901

• A recombinant Escherichia coli whole cell biocatalyst harboring a cytochrome P450cam monooxygenase system coupled with enzymatic cofactor regeneration.

  Applied microbiology and biotechnology 20060901

• Regulation of myocardial substrate metabolism during increased energy expenditure: insights from computational studies.

  American journal of physiology. Heart and circulatory physiology 20060901

• Molecular dynamics simulations of NAD+-induced domain closure in horse liver alcohol dehydrogenase.

  Biophysical journal 20060901

• NAD+ and NADH in cellular functions and cell death.

  Frontiers in bioscience : a journal and virtual library 20060901

• Amino acid residues that determine functional specificity of NADP- and NAD-dependent isocitrate and isopropylmalate dehydrogenases.

  Proteins 20060901

• Fingerprinting DHFR in single-molecule AFM studies.

  Biophysical journal 20060901

• Reevaluation of the Griess reaction: how much of a problem is interference by nicotinamide nucleotides?

  Analytical biochemistry 20060901

• Chiral inversion of RS-8359: a selective and reversible MAO-A inhibitor via oxido-reduction of keto-alcohol.

  Chirality 20060901

• Molecular basis of substrate recognition in D-3-hydroxybutyrate dehydrogenase from Pseudomonas putida.

  Chembiochem : a European journal of chemical biology 20060901

• Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid.

  Nature medicine 20060901

• Negative kinetic temperature effect on the hydride transfer from NADH analogue BNAH to the radical cation of N-benzylphenothiazine in acetonitrile.

  The Journal of organic chemistry 20060901

• Trypanosoma brucei UDP-galactose-4'-epimerase in ternary complex with NAD+ and the substrate analogue UDP-4-deoxy-4-fluoro-alpha-D-galactose.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060901

• The metabolism of fatty alcohols in lipid nanoparticles by alcohol dehydrogenase.

  Drug development and industrial pharmacy 20060901

• Alteration of coenzyme specificity of lactate dehydrogenase from Thermus thermophilus by introducing the loop region of NADP(H)-dependent malate dehydrogenase.

  Bioscience, biotechnology, and biochemistry 20060901

• The UChA and UChB rat lines: metabolic and genetic differences influencing ethanol intake.

  Addiction biology 20060901

• How to keep glycolytic metabolite concentrations constant when ATP/ADP and NADH/NAD+ change.

  Systems biology 20060901

• Detection of NADPH-diaphorase activity in Paramecium primaurelia.

  European journal of protistology 20060901

• Beneficial effect of low ethanol intake on the cardiovascular system: possible biochemical mechanisms.

  Vascular health and risk management 20060901

• An NADH-tetrazolium-coupled sensitive assay for malate dehydrogenase in mitochondria and crude tissue homogenates.

  Journal of biochemical and biophysical methods 20060831

• Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combination with antineoplastic agents.

  European journal of medical research 20060830

• Structural basis for the alteration of coenzyme specificity in a malate dehydrogenase mutant.

  Biochemical and biophysical research communications 20060825

• Induction of ROS formation, poly(ADP-ribose) polymerase-1 activation, and cell death by PCB126 and PCB153 in human T47D and MDA-MB-231 breast cancer cells.

  Chemico-biological interactions 20060825

• Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060816

• Synthetic lethal and biochemical analyses of NAD and NADH kinases in Saccharomyces cerevisiae establish separation of cellular functions.

  The Journal of biological chemistry 20060811

• Probing hot spots at protein-ligand binding sites: a fragment-based approach using biophysical methods.

  Journal of medicinal chemistry 20060810

• Novel methylenephosphophosphonate analogues of mycophenolic adenine dinucleotide. Inhibition of inosine monophosphate dehydrogenase.

  Journal of medicinal chemistry 20060810

• Selective alteration of the rate-limiting step in cytosolic aldehyde dehydrogenase through random mutagenesis.

  Biochemistry 20060808

• Hypoxia regulates bone morphogenetic protein signaling through C-terminal-binding protein 1.

  Circulation research 20060804

• Catalytic hydrogenation of alpha,beta-epoxy ketones to form beta-hydroxy ketones mediated by an NADH coenzyme model.

  Organic letters 20060803

• Cofactor assisted gating mechanism in the active site of NADH oxidase from Thermus thermophilus.

  Proteins 20060801

• Indole-3-acetic acid regulates the central metabolic pathways in Escherichia coli.

  Microbiology (Reading, England) 20060801

• Structure of apo-glyceraldehyde-3-phosphate dehydrogenase from Synechococcus PCC7942.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060801

• Flow-injection determination of thyroxine using immobilized enzyme with tris(2,2'-bipyridyl)ruthenium(III) chemiluminescence detection.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20060801

• Insights into the sirtuin mechanism from ternary complexes containing NAD+ and acetylated peptide.

  Structure (London, England : 1993) 20060801

• Kinamycins A and C, bacterial metabolites that contain an unusual diazo group, as potential new anticancer agents: antiproliferative and cell cycle effects.

  Anti-cancer drugs 20060801

• Occurrence of thioredoxin reductase in Deinococcus species, the UV resistant bacteria.

  Journal of microbiology (Seoul, Korea) 20060801

• Enhanced oxidation of NAD(P)H by oxidants in the presence of dehydrogenases but no evidence for a superoxide-propagated chain oxidation of the bound coenzymes.

  Free radical research 20060801

• Sirtuins in aging and age-related disease.

  Cell 20060728

• Insight through molecular mechanics Poisson-Boltzmann surface area calculations into the binding affinity of triclosan and three analogues for FabI, the E. coli enoyl reductase.

  Journal of medicinal chemistry 20060727

• Role of the His57-Glu214 ionic couple located in the active site of Mycobacterium tuberculosis FprA.

  Biochemistry 20060725

• Structural basis for stereoselectivity in the (R)- and (S)-hydroxypropylthioethanesulfonate dehydrogenases.

  Biochemistry 20060725

• An isothermal titration calorimetry study of the binding of substrates and ligands to the tartrate dehydrogenase from Pseudomonas putida reveals half-of-the-sites reactivity.

  Biochemistry 20060725

• Elevated cytosolic Na+ decreases mitochondrial Ca2+ uptake during excitation-contraction coupling and impairs energetic adaptation in cardiac myocytes.

  Circulation research 20060721

• Crystal structure of nicotinic acid mononucleotide adenylyltransferase from Staphyloccocus aureus: structural basis for NaAD interaction in functional dimer.

  Journal of molecular biology 20060721

• Regulation of intracellular levels of NAD: a novel role for CD38.

  Biochemical and biophysical research communications 20060714

• Development and characterization of an immobilized enzyme reactor (IMER) based on human glyceraldehyde-3-phosphate dehydrogenase for on-line enzymatic studies.

  Journal of chromatography. A 20060707

• Substrate specificity of soluble and membrane-associated ADP-ribosyltransferase ART2.1.

  Journal of cellular biochemistry 20060701

• The stamp of ancestry: roots of behavioral and neuronal impairment in adulthood.

  Experimental neurology 20060701

• Mitochondrial inhibition prior to oxygen-withdrawal facilitates the occurrence of hypoxia-induced spreading depression in rat hippocampal slices.

  Journal of neurophysiology 20060701

• Early steps in the biosynthesis of NAD in Arabidopsis start with aspartate and occur in the plastid.

  Plant physiology 20060701

• CD38 induces apoptosis of a murine pro-B leukemic cell line by a tyrosine kinase-dependent but ADP-ribosyl cyclase- and NAD glycohydrolase-independent mechanism.

  International immunology 20060701

• Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme.

  Nature structural & molecular biology 20060701

• Mitochondria from the left heart ventricles of both normotensive and spontaneously hypertensive rats oxidize externally added NADH mostly via a novel malate/oxaloacetate shuttle as reconstructed in vitro.

  International journal of molecular medicine 20060701

• Mitochondrial reactive oxygen species are required for hypothalamic glucose sensing.

  Diabetes 20060701

• Two highly divergent alcohol dehydrogenases of melon exhibit fruit ripening-specific expression and distinct biochemical characteristics.

  Plant molecular biology 20060701

• Influence of poly(ADP-ribose) polymerase-1 and its apoptotic 24-kD fragment on repair of DNA duplexes in bovine testis nuclear extract.

  Biochemistry. Biokhimiia 20060701

• [Fluorescence spectral characteristics of human blood and its endogenous fluorophores].

  Guang pu xue yu guang pu fen xi = Guang pu 20060701

• Lys-D48 is required for charge stabilization, rapid flavin reduction, and internal electron transfer in the catalytic cycle of dihydroorotate dehydrogenase B of Lactococcus lactis.

  The Journal of biological chemistry 20060630

• Zinc-dependent multi-conductance channel activity in mitochondria isolated from ischemic brain.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060621

• Kinetic enzymatic determination of glycerol in wine and beer using a sequential injection system with spectrophotometric detection.

  Journal of agricultural and food chemistry 20060614

• Crystallographic and pre-steady-state kinetics studies on binding of NADH to wild-type and isoniazid-resistant enoyl-ACP(CoA) reductase enzymes from Mycobacterium tuberculosis.

  Journal of molecular biology 20060609

• Thiamin biosynthesis in eukaryotes: characterization of the enzyme-bound product of thiazole synthase from Saccharomyces cerevisiae and its implications in thiazole biosynthesis.

  Journal of the American Chemical Society 20060607

• Metabolism of lactose by Clostridium thermolacticum growing in continuous culture.

  Archives of microbiology 20060601

• CCL5 evokes calcium signals in microglia through a kinase-, phosphoinositide-, and nucleotide-dependent mechanism.

  Journal of neuroscience research 20060601

• Catalysis of regioselective reduction of NAD+ by ruthenium(II) arene complexes under biologically relevant conditions.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20060601

• Accumulation of poly(ADP-ribose) polymerase inhibitors in children with chronic renal failure.

  Pediatric nephrology (Berlin, Germany) 20060601

• An assay for Fe(II)/2-oxoglutarate-dependent dioxygenases by enzyme-coupled detection of succinate formation.

  Analytical biochemistry 20060601

• The action of extracellular NAD+ on gluconeogenesis in the perfused rat liver.

  Molecular and cellular biochemistry 20060601

• 11beta-Hydroxysteroid dehydrogenase activity in pregnancies complicated by hydatidiform mole.

  American journal of reproductive immunology (New York, N.Y. : 1989) 20060601

• Sensitive and meaningful measures of bacterial metabolic activity using NADH fluorescence.

  Water research 20060601

• Effect of mangiferin on mitochondrial energy production in experimentally induced myocardial infarcted rats.

  Vascular pharmacology 20060601

• Alcoholic ketoacidosis.

  Emergency medicine journal : EMJ 20060601

• The ACCEL model for accelerating the detoxification kinetics of hydrocarbons requiring initial monooxygenation reactions.

  Biodegradation 20060601

• Reexamining the hyperglycemic pseudohypoxia hypothesis of diabetic oculopathy.

  Investigative ophthalmology & visual science 20060601

• Characterization of E. coli tetrameric aldehyde dehydrogenases with atypical properties compared to other aldehyde dehydrogenases.

  Protein science : a publication of the Protein Society 20060601

• Insulin-stimulated NADH/NAD+ redox state increases NAD(P)H oxidase activity in cultured rat vascular smooth muscle cells.

  American journal of hypertension 20060601

• Crystallization and preliminary crystallographic analysis of NAD+-preferring aldohexose dehydrogenase from the thermoacidophilic archaeon Thermoplasma acidophilum.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060601

• Expression, purification and preliminary crystallographic analysis of the Toxoplasma gondii enoyl reductase.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060601

• DNA oxidative damage by terpene catechols as analogues of natural terpene quinone methide precursors in the presence of Cu(II) and/or NADH.

  Chemical research in toxicology 20060601

• Molecular cloning of a novel type of rat cytoplasmic 17beta-hydroxysteroid dehydrogenase distinct from the type 5 isozyme.

  Journal of biochemistry 20060601

• [Properties of a triphenylmethane dyes decolorization enzyme TpmD from Aeromonas hydrophila strain DN322].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20060601

• Redox-responsive in vitro modulation of the signalling state of the isolated PrrB sensor kinase of Rhodobacter sphaeroides NCIB 8253.

  FEBS letters 20060529

• Study on the influence of potassium iodate on the metabolism of Escherichia coli by intrinsic fluorescence.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060515

• The simultaneous measurement of nicotinamide adenine dinucleotide and related compounds by liquid chromatography/electrospray ionization tandem mass spectrometry.

  Analytical biochemistry 20060515

• The role of invariant amino acid residues at the hydride transfer site of proton-translocating transhydrogenase.

  The Journal of biological chemistry 20060512

• Unusual temperature dependence of enantioselectivity in asymmetric reductions by chiral NADH models.

  Organic letters 20060511

• Novel 6-formylpterin derivatives: chemical synthesis and O2 to ROS conversion activities.

  Organic & biomolecular chemistry 20060507

• Crystal structure of prephenate dehydrogenase from Aquifex aeolicus. Insights into the catalytic mechanism.

  The Journal of biological chemistry 20060505

• The crystal structure of the apoenzyme of the iron-sulphur cluster-free hydrogenase.

  Journal of molecular biology 20060505

• TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion.

  The EMBO journal 20060503

• Poly(ADP-ribose) accumulation and enhancement of postischemic brain damage in 110-kDa poly(ADP-ribose) glycohydrolase null mice.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060501

• Nicotinamide adenine dinucleotide is released from sympathetic nerve terminals via a botulinum neurotoxin A-mediated mechanism in canine mesenteric artery.

  American journal of physiology. Heart and circulatory physiology 20060501

• Clinicopathological phenotype of ALS with a novel G72C SOD1 gene mutation mimicking a myopathy.

  Muscle & nerve 20060501

• Buformin suppresses the expression of glyceraldehyde 3-phosphate dehydrogenase.

  Biological & pharmaceutical bulletin 20060501

• Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathway.

  International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20060501

• Steady-state kinetics and inhibitory action of antitubercular phenothiazines on mycobacterium tuberculosis type-II NADH-menaquinone oxidoreductase (NDH-2).

  The Journal of biological chemistry 20060428

• Use of substrate analogs and mutagenesis to study substrate binding and catalysis in the Sir2 family of NAD-dependent protein deacetylases.

  The Journal of biological chemistry 20060428

• Crystal structures of the short-chain flavin reductase HpaC from Sulfolobus tokodaii strain 7 in its three states: NAD(P)(+)(-)free, NAD(+)(-)bound, and NADP(+)(-)bound.

  Biochemistry 20060425

• Activation of the adenylyl cyclase/protein kinase A pathway facilitates neural release of beta-nicotinamide adenine dinucleotide in canine mesenteric artery.

  European journal of pharmacology 20060424

• TNF regulates cellular NAD+ metabolism in primary macrophages.

  Biochemical and biophysical research communications 20060421

• Biofilm effects on the peroxidase-oxidase reaction.

  The journal of physical chemistry. B 20060420

• The CD38-independent ADP-ribosyl cyclase from mouse brain synaptosomes: a comparative study of neonate and adult brain.

  The Biochemical journal 20060415

• Ca2+ controls slow NAD(P)H oscillations in glucose-stimulated mouse pancreatic islets.

  The Journal of physiology 20060415

• Targeted disruption of CD38 accelerates autoimmune diabetes in NOD/Lt mice by enhancing autoimmunity in an ADP-ribosyltransferase 2-dependent fashion.

  Journal of immunology (Baltimore, Md. : 1950) 20060415

• Glycolytic sequence and respiration of Debaryomyces hansenii as compared to Saccharomyces cerevisiae.

  Yeast (Chichester, England) 20060415

• The mammalian longevity-associated gene product p66shc regulates mitochondrial metabolism.

  The Journal of biological chemistry 20060414

• Hydrogen peroxide-mediated isoniazid activation catalyzed by Mycobacterium tuberculosis catalase-peroxidase (KatG) and its S315T mutant.

  Biochemistry 20060404

• Satraplatin activation by haemoglobin, cytochrome C and liver microsomes in vitro.

  Cancer chemotherapy and pharmacology 20060401

• Mechanistic characterization of the MSDH (methylmalonate semialdehyde dehydrogenase) from Bacillus subtilis.

  The Biochemical journal 20060401

• Nitric oxide scavenging by barley hemoglobin is facilitated by a monodehydroascorbate reductase-mediated ascorbate reduction of methemoglobin.

  Planta 20060401

• Carcinogenic 3-nitrobenzanthrone induces oxidative damage to isolated and cellular DNA.

  Free radical biology & medicine 20060401

• The increase in the number of accessible SH-groups in the enterococcal membrane vesicles by ATP and nicotinamide adenine dinucleotides.

  Current microbiology 20060401

• Presence of NAD+-specific glyceraldehyde-3-phosphate dehydrogenase and CcpA-dependent transcription of its gene in the ruminal bacterium Streptococcus bovis.

  FEMS microbiology letters 20060401

• Detection of superoxide anion generation by equine spermatozoa.

  American journal of veterinary research 20060401

• A potential mechanism of energy-metabolism oscillation in an aerobic chemostat culture of the yeast Saccharomyces cerevisiae.

  The FEBS journal 20060401

• Comparison of metabolic fates of nicotinamide, NAD+ and NADH administered orally and intraperitoneally; characterization of oral NADH.

  Journal of nutritional science and vitaminology 20060401

• Crystal structures of human glycerol 3-phosphate dehydrogenase 1 (GPD1).

  Journal of molecular biology 20060331

• Synthesis, properties, and NAD+-NADH-type redox ability of 14-substituted 1,3-dimethyl-5,10-methanocycloundeca[4,5]pyrrolo[2,3-d]pyrimidine-2,4(1,3h)-dionylium tetrafluoroborates and their hydride adducts.

  The Journal of organic chemistry 20060331

• Enhancement of streptolysin O activity and intrinsic cytotoxic effects of the group A streptococcal toxin, NAD-glycohydrolase.

  The Journal of biological chemistry 20060324

• Coenzyme Q(1) depletes NAD(P)H and impairs recycling of ascorbate in astrocytes.

  Brain research 20060317

• Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 A resolution reveals intriguing extra electron density in the active site.

  Proteins 20060315

• Quantitative multiplex CARS spectroscopy in congested spectral regions.

  The journal of physical chemistry. B 20060309

• Secoisolariciresinol dehydrogenase: mode of catalysis and stereospecificity of hydride transfer in Podophyllum peltatum.

  Organic & biomolecular chemistry 20060307

• Solid phase synthesis of a redox delivery system with the aim of targeting peptides into the brain.

  Organic & biomolecular chemistry 20060307

• Nucleotide-binding sites in the voltage-dependent anion channel: characterization and localization.

  The Journal of biological chemistry 20060303

• Conformational diversity of ligands bound to proteins.

  Journal of molecular biology 20060303

• Control of the synthesis and subcellular targeting of the two GDH genes products in leaves and stems of Nicotiana plumbaginifolia and Arabidopsis thaliana.

  Plant & cell physiology 20060301

• Effects of 8-OH-DPAT on hippocampal NADH fluorescence in vivo in anaesthetized rats.

  Journal of neuroscience research 20060301

• Expression of a novel P275L variant of NADH:cytochrome b5 reductase gives functional insight into the conserved motif important for pyridine nucleotide binding.

  Archives of biochemistry and biophysics 20060301

• Molecular recognition between protein and nicotinamide dinucleotide in intact, proton-translocating transhydrogenase studied by ATR-FTIR Spectroscopy.

  Journal of the American Chemical Society 20060301

• Unlocking the secrets of longevity genes.

  Scientific American 20060301

• MafA expression and insulin promoter activity are induced by nicotinamide and related compounds in INS-1 pancreatic beta-cells.

  Diabetes 20060301

• Stabilization of a formate dehydrogenase by covalent immobilization on highly activated glyoxyl-agarose supports.

  Biomacromolecules 20060301

• Structure-guided engineering of xylitol dehydrogenase cosubstrate specificity.

  Structure (London, England : 1993) 20060301

• Isolation and bioenergetic characterization of mitochondria from Pichia pastoris.

  Yeast (Chichester, England) 20060301

• Effects of anesthesia on the responses to cortical spreading depression in the rat brain in vivo.

  Neurological research 20060301

• Cloning, expression, and characterization of a DNA ligase from a hyperthermophilic archaeon Thermococcus sp.

  Biotechnology letters 20060301

• Effect of resveratrol on nitrate tolerance in isolated human internal mammary artery.

  Journal of cardiovascular pharmacology 20060301

• Low-potential nicotinamide adenine dinucleotide detection at a glassy carbon electrode modified with toluidine blue O functionalized multiwall carbon nanotubes.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20060301

• Metabolic signalling in defence and stress: the central roles of soluble redox couples.

  Plant, cell & environment 20060301

• High-throughput enzymatic method for enantiomeric excess determination of O-acetylated cyanohydrins.

  Journal of the American Chemical Society 20060222

• Electrochemistry of immobilized redox enzymes: kinetic characteristics of NADH oxidation catalysis at diaphorase monolayers affinity immobilized on electrodes.

  Journal of the American Chemical Society 20060215

• Neuronal and astrocytic shuttle mechanisms for cytosolic-mitochondrial transfer of reducing equivalents: current evidence and pharmacological tools.

  Biochemical pharmacology 20060214

• beta-NAD is a novel nucleotide released on stimulation of nerve terminals in human urinary bladder detrusor muscle.

  American journal of physiology. Renal physiology 20060201

• Levels of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase are reduced in inflammatory bowel disease: evidence for involvement of TNF-alpha.

  American journal of physiology. Gastrointestinal and liver physiology 20060201

• Extracellular NAD+ regulates intracellular calcium levels and induces activation of human granulocytes.

  The Biochemical journal 20060201

• Catalysis of NADH-->NADP+ transhydrogenation by adult Hymenolepis diminuta mitochondria.

  Parasitology research 20060201

• Utilization of substrate-induced quenching for screening targets promoting NADH and NADPH consumption.

  Journal of biomolecular screening 20060201

• Characterization of a GDP-D-mannose 3'',5''-epimerase from rice.

  Phytochemistry 20060201

• Involvement of a glycerol-3-phosphate dehydrogenase in modulating the NADH/NAD+ ratio provides evidence of a mitochondrial glycerol-3-phosphate shuttle in Arabidopsis.

  The Plant cell 20060201

• Deoxyribonuclease 1 aggravates acetaminophen-induced liver necrosis in male CD-1 mice.

  Hepatology (Baltimore, Md.) 20060201

• DNA ligases: structure, reaction mechanism, and function.

  Chemical reviews 20060201

• A kinetic study on the phenothiazine dependent oxidation of NADH by bovine ceruloplasmin.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20060201

• Crystallization of the NADH-oxidizing domain of the Na+-translocating NADH:ubiquinone oxidoreductase from Vibrio cholerae.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060201

• D-3-hydroxybutyrate dehydrogenase from Pseudomonas fragi: molecular cloning of the enzyme gene and crystal structure of the enzyme.

  Journal of molecular biology 20060127

• Mechanistic analysis of the unusual redox-elimination sequence employed by Thermotoga maritima BglT: a 6-phospho-beta-glucosidase from glycoside hydrolase family 4.

  Biochemistry 20060117

• Sequential injection system for the enzymatic determination of ethanol in wine.

  Journal of agricultural and food chemistry 20060111

• Crystal structure and enzyme kinetics of the (S)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain EbN1.

  Biochemistry 20060110

• SIRT1 top 40 hits: use of one-bead, one-compound acetyl-peptide libraries and quantum dots to probe deacetylase specificity.

  Biochemistry 20060110

• Interactions between phospholipids and NADH:ubiquinone oxidoreductase (complex I) from bovine mitochondria.

  Biochemistry 20060110

• Sir2 protein deacetylases: evidence for chemical intermediates and functions of a conserved histidine.

  Biochemistry 20060110

• Liver parenchyma heterogeneity in the response to extracellular NAD+.

  Cell biochemistry and function 20060101

• Use of oxidoreduction potential as an indicator to regulate 1,3-propanediol fermentation by Klebsiella pneumoniae.

  Applied microbiology and biotechnology 20060101

• Cardiac mitochondrial preconditioning by Big Ca2+-sensitive K+ channel opening requires superoxide radical generation.

  American journal of physiology. Heart and circulatory physiology 20060101

• Evaluation of a new enzymatic method for homocysteine measurement.

  Clinical biochemistry 20060101

• Interference and blood sample preparation for a pyruvate enzymatic assay.

  Clinical biochemistry 20060101

• Nucleotides induce higher order chromatin degradation.

  Molecular and cellular biochemistry 20060101

• Acetaldehyde inhibits the formation of retinoic acid from retinal in the rat esophagus.

  Scandinavian journal of gastroenterology 20060101

• High-resolution intravital NADH fluorescence microscopy allows measurements of tissue bioenergetics in rat ileal mucosa.

  Microcirculation (New York, N.Y. : 1994) 20060101

• Tissue bioenergetics and microvascular perfusion are impaired in rat ileal mucosa in normotensive sepsis.

  Microcirculation (New York, N.Y. : 1994) 20060101

• Inhibition of human mitochondrial aldehyde dehydrogenase by 4-hydroxynon-2-enal and 4-oxonon-2-enal.

  Chemical research in toxicology 20060101

• Loss of NAD(H) from swollen yeast mitochondria.

  BMC biochemistry 20060101

• In vivo monitoring the changes of interstitial pH and FAD/NADH ratio by fluorescence spectroscopy in healing skin wounds.

  Photochemistry and photobiology 20060101

• In beta-cells, mitochondria integrate and generate metabolic signals controlling insulin secretion.

  The international journal of biochemistry & cell biology 20060101

• The redox switch/redox coupling hypothesis.

  Neurochemistry international 20060101

• Novel localization of CD38 in perivascular sympathetic nerve terminals.

  Neuroscience 20060101

• NAD(H) recycling activity of an engineered bifunctional enzyme galactose dehydrogenase/lactate dehydrogenase.

  International journal of biological sciences 20060101

• Effect of overexpression of a soluble pyridine nucleotide transhydrogenase (UdhA) on the production of poly(3-hydroxybutyrate) in Escherichia coli.

  Biotechnology progress 20060101

• Cell Life versus cell longevity: the mysteries surrounding the NAD+ precursor nicotinamide.

  Current medicinal chemistry 20060101

• Photosensitized oxidation and inactivation of pyocyanin, a virulence factor of Pseudomonas aeruginosa.

  Photochemistry and photobiology 20060101

• Pyrene excimer fluorescence of yeast alcohol dehydrogenase: a sensitive probe to investigate ligand binding and unfolding pathway of the enzyme.

  Photochemistry and photobiology 20060101

• Generation of superoxide by the mitochondrial Complex I.

  Biochimica et biophysica acta 20060101

• Tryptophan-niacin metabolism in rat with puromycin aminonucleoside-induced nephrosis.

  International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20060101

• NAD(P) synthesis and pyridine nucleotide cycling in plants and their potential importance in stress conditions.

  Journal of experimental botany 20060101

• ADP-ribosylation of membrane proteins: unveiling the secrets of a crucial regulatory mechanism in mammalian cells.

  Annals of medicine 20060101

• The biochemistry of sirtuins.

  Annual review of biochemistry 20060101

• [Cellular mechanisms of induction of apoptosis in human erythroleukaemic K562 cells line treated by quinoline-N-oxide derivatives].

  Biomeditsinskaia khimiia 20060101

• Slow-onset inhibition of 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis by an inorganic complex.

  Current pharmaceutical design 20060101

• Adult central core disease. Clinical, histologic and genetic aspects: case report and review of the literature.

  Clinical neuropathology 20060101

• [Alteration of CD38 expression and NAD+ metabolism induced by Doxorubicin in bone marrow cells].

  Eksperimental'naia i klinicheskaia farmakologiia 20060101

• Stimulation by cytochrome c of the external pathway of NADH oxidation and ascorbate oxidation in the presence of TMPD.

  Doklady. Biochemistry and biophysics 20060101

• Reduction of nitroaromatic compounds by NAD(P)H:quinone oxidoreductase (NQO1): the role of electron-accepting potency and structural parameters in the substrate specificity.

  Acta biochimica Polonica 20060101

• The novel nucleotide 4KNTP, in high concentrations in erythrocytes of renal failure children: a comparison with accumulation of other putative precursors in the plasma.

  Nucleosides, nucleotides & nucleic acids 20060101

• Liquid chromatographic/mass spectrometric procedure for measurement of NAD catabolites in human and rat plasma and urine.

  Nucleosides, nucleotides & nucleic acids 20060101

• An immunoglobulin A1 that inhibits lactate dehydrogenase activity, with reversal of inhibition by addition of NADH.

  Annals of clinical and laboratory science 20060101

• Role of poly(ADP-ribose) polymerase during vascular reconstruction.

  Vascular 20060101

• Chemical natures and application of 6-formylpterin derivatives.

  Nucleic acids symposium series (2004) 20060101

• [Bioluminescent method for determination of concentration metabolic substrates and NAD+ in the lymphocytes].

  Biomeditsinskaia khimiia 20060101

• Catalases are NAD(P)H-dependent tellurite reductases.

  PloS one 20060101

• Antioxidant capacity of crude extracts from clones of banana and plane species.

  Journal of medicinal food 20060101

• Comparison of glycolytic NADH oscillations in yeasts Saccharomyces cerevisiae and Saccharomyces carlsbergensis.

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20060101

• Prooxidant cytotoxicity of chromate in mammalian cells: the opposite roles of DT-diaphorase and glutathione reductase.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20060101

• CD38 and CD157: biological observations to clinical therapeutic targets.

  Molecular medicine (Cambridge, Mass.) 20060101

• Emerging functions of extracellular pyridine nucleotides.

  Molecular medicine (Cambridge, Mass.) 20060101

• High-throughput screening of activity and enantioselectivity of esterases.

  Nature protocols 20060101

• Acquisition of iron by enterococci: some properties and role of assimilating ferric iron reductases.

  Polish journal of microbiology 20060101

• Isatin interaction with glyceraldehyde-3-phosphate dehydrogenase, a putative target of neuroprotective drugs: partial agonism with deprenyl.

  Journal of neural transmission. Supplementum 20060101

• The Saccharomyces cerevisiae COQ10 gene encodes a START domain protein required for function of coenzyme Q in respiration.

  The Journal of biological chemistry 20051230

• Theophylline prevents NAD+ depletion via PARP-1 inhibition in human pulmonary epithelial cells.

  Biochemical and biophysical research communications 20051230

• Alpha-ketoglutarate dehydrogenase: a target and generator of oxidative stress.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20051229

• Structure and function of GDP-mannose-3',5'-epimerase: an enzyme which performs three chemical reactions at the same active site.

  Journal of the American Chemical Society 20051228

• Dependence of enzyme reaction mechanism on protonation state of titratable residues and QM level description: lactate dehydrogenase.

  Chemical communications (Cambridge, England) 20051221

• Analysis of interactions with mitochondrial mRNA using mutant forms of yeast NAD(+)-specific isocitrate dehydrogenase.

  Biochemistry 20051220

• Ethanol increases mitochondrial cytochrome P450 2E1 in mouse liver and rat hepatocytes.

  FEBS letters 20051219

• Aerobic 2- and 4-nitroreduction of CB 1954 by human liver.

  Toxicology 20051215

• Regulation of lactate production at the onset of ischaemia is independent of mitochondrial NADH/NAD+: insights from in silico studies.

  The Journal of physiology 20051215

• Functional coupling between vanillate-O-demethylase and formaldehyde detoxification pathway.

  FEMS microbiology letters 20051215

• Mediatorless voltammetric oxidation of NADH and sensing of ethanol.

  Biosensors & bioelectronics 20051215

• Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1.

  Journal of medicinal chemistry 20051215

• Intermolecular electron-transfer reactions in soluble methane monooxygenase: a role for hysteresis in protein function.

  Journal of the American Chemical Society 20051214

• Structure of lactate dehydrogenase from Plasmodium vivax: complexes with NADH and APADH.

  Biochemistry 20051213

• Crystal structures of Delta1-piperideine-2-carboxylate/Delta1-pyrroline-2-carboxylate reductase belonging to a new family of NAD(P)H-dependent oxidoreductases: conformational change, substrate recognition, and stereochemistry of the reaction.

  The Journal of biological chemistry 20051209

• The first chemical synthesis of the core structure of the benzoylhydrazine-NAD adduct, a competitive inhibitor of the Mycobacterium tuberculosis enoyl reductase.

  The Journal of organic chemistry 20051209

• A role for BARS at the fission step of COPI vesicle formation from Golgi membrane.

  The EMBO journal 20051207

• Study on the toxicity of phenolic and phenoxy herbicides using the submitochondrial particle assay.

  Toxicology in vitro : an international journal published in association with BIBRA 20051201

• Ion channel clustering enhances weak electric field detection by neutrophils: apparent roles of SKF96365-sensitive cation channels and myeloperoxidase trafficking in cellular responses.

  European biophysics journal : EBJ 20051201

• A preliminary account of the properties of recombinant human Glyoxylate reductase (GRHPR), LDHA and LDHB with glyoxylate, and their potential roles in its metabolism.

  Biochimica et biophysica acta 20051201

• New insights into the mechanism of permeation through large channels.

  Biophysical journal 20051201

• Trypanosoma cruzi: preliminary investigation of NADH-positive and somatostatin-immunoreactive neurons in the myenteric plexus of the mouse colon during the infection.

  Experimental parasitology 20051201

• Temporal changes in cellular energy following burn injury.

  Burns : journal of the International Society for Burn Injuries 20051201

• Opposing effects of oestradiol and progesterone on intracellular pathways and activation processes in the oxidative stress induced activation of cultured rat hepatic stellate cells.

  Gut 20051201

• Molecular evidence of sorbitol dehydrogenase in tomato, a non-Rosaceae plant.

  Phytochemistry 20051201

• Stability and comparative metabolism of selected felbamate metabolites and postulated fluorofelbamate metabolites by postmitochondrial suspensions.

  Chemical research in toxicology 20051201

• The action of quercetin on the mitochondrial NADH to NAD(+) ratio in the isolated perfused rat liver.

  Planta medica 20051201

• Recognition site for the side chain of 2-ketoacid substrate in d-lactate dehydrogenase.

  Journal of biochemistry 20051201

• Crystal structures of an NAD kinase from Archaeoglobus fulgidus in complex with ATP, NAD, or NADP.

  Journal of molecular biology 20051125

• Novel synthesis, properties, and NAD+-NADH type redox ability of 1,3-dimethylcyclohepta[4,5]pyrrolo[2,3-d]pyrimidine- 2,4(1,3h)-dionylium ions annulated with additional pyrrolo[2,3-d]pyrimidine-1,3(2,4h)-dione and furan analogue, and their hydride adducts.

  The Journal of organic chemistry 20051125

• ADP-ribosyl cyclase and GDP-ribosyl cyclase activities are not always equivalent: impact on the study of the physiological role of cyclic ADP-ribose.

  Analytical biochemistry 20051115

• Interaction between astrocytes and neurons studied using a mathematical model of compartmentalized energy metabolism.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20051101

• Catalytic mechanism of S-adenosylhomocysteine hydrolase: roles of His 54, Asp130, Glu155, Lys185, and Aspl89.

  The international journal of biochemistry & cell biology 20051101

• Ligand binding modulates the mechanical stability of dihydrofolate reductase.

  Biophysical journal 20051101

• Gold nanoparticles: catalyst for the oxidation of NADH to NAD(+).

  Journal of photochemistry and photobiology. B, Biology 20051101

• Molecular analysis of an NAD-dependent alcohol dehydrogenase from the zygomycete Mucor circinelloides.

  Molecular genetics and genomics : MGG 20051101

• Biochemical characterization of trinitrotoluene transforming oxygen-insensitive nitroreductases from Clostridium acetobutylicum ATCC 824.

  Archives of microbiology 20051101

• High-level expression and characterization of the recombinant enzyme, and tissue distribution of human succinic semialdehyde dehydrogenase.

  Protein expression and purification 20051101

• Single amino acid exchanges in FAD-binding domains of squalene epoxidase of Saccharomyces cerevisiae lead to either loss of functionality or terbinafine sensitivity.

  Biochemical Society transactions 20051101

• Prevention of mitochondrial dysfunction in post-traumatic mouse brain by superoxide dismutase.

  Journal of neurochemistry 20051101

• Isoflurane postconditioning prevents opening of the mitochondrial permeability transition pore through inhibition of glycogen synthase kinase 3beta.

  Anesthesiology 20051101

• Reconstitution and properties of the recombinant glyceraldehyde-3-phosphate dehydrogenase/CP12/phosphoribulokinase supramolecular complex of Arabidopsis.

  Plant physiology 20051101

• Ca(2+) rise within a narrow window of concentration prevents functional injury of mitochondria exposed to hypoxia/reoxygenation by increasing antioxidative defence.

  The FEBS journal 20051101

• Effects of beauvericin on the metabolic state and ionic homeostasis of ventricular myocytes of the guinea pig.

  Chemical research in toxicology 20051101

• Homogeneous enzymatic assay for L-cysteine with betaC-S lyase.

  Bioscience, biotechnology, and biochemistry 20051101

• Edge plane pyrolytic graphite electrodes in electroanalysis: an overview.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20051101

• The pathogenesis and significance of the urinary alcohol cycle in rats fed ethanol intragastrically.

  Alcoholism, clinical and experimental research 20051101

• [Alcohol dehydrogenase interference in clinical chemical laboratory tests].

  Rinsho byori. The Japanese journal of clinical pathology 20051101

• Changes in FAD and NADH fluorescence in neurosecretory terminals are triggered by calcium entry and by ADP production.

  The Journal of membrane biology 20051101

• NAD-, NMN-, and NADP-dependent modification of dinitrogenase reductases from Rhodospirillum rubrum and Azotobacter vinelandii.

  FEBS letters 20051024

• Dynamic changes in nicotinamide pyridine dinucleotide content in normal human epidermal keratinocytes and their effect on retinoic acid biosynthesis.

  Biochemical and biophysical research communications 20051021

• Evolution. Changing the cofactor diet of an enzyme.

  Science (New York, N.Y.) 20051021

• The biochemical architecture of an ancient adaptive landscape.

  Science (New York, N.Y.) 20051021

• In vitro co-metabolism of acetoacetate and ethanol in human hepatic mitochondrial and cytosolic fractions.

  Chemico-biological interactions 20051020

• Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme.

  The EMBO journal 20051019

• Mutagenesis of Glycine 179 modulates both catalytic efficiency and reduced pyridine nucleotide specificity in cytochrome b5 reductase.

  Biochemistry 20051018

• C-terminal tyrosine of ferredoxin-NADP+ reductase in hydride transfer processes with NAD(P)+/H.

  Biochemistry 20051018

• Magnesium and phosphate ions enable NAD binding to methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase.

  The Journal of biological chemistry 20051007

• Enzyme kinetics of zearalenone biotransformation: pH and cofactor effects.

  Archives of toxicology 20051001

• TRPM2 and TRPM7: channel/enzyme fusions to generate novel intracellular sensors.

  Pflugers Archiv : European journal of physiology 20051001

• Direct quantification of analyte concentration by resonant acoustic profiling.

  Clinical chemistry 20051001

• Induction of mitochondrial oxidative stress in astrocytes by nitric oxide precedes disruption of energy metabolism.

  Journal of neurochemistry 20051001

• Interactions between dehydroepiandrosterone and glucocorticoid metabolism in pig kidney: nuclear and microsomal 11beta-hydroxysteroid dehydrogenases.

  Archives of biochemistry and biophysics 20051001

• Mechanism of flavin transfer and oxygen activation by the two-component flavoenzyme styrene monooxygenase.

  Archives of biochemistry and biophysics 20051001

• NAD- and NADP-dependent mitochondrially targeted methylenetetrahydrofolate dehydrogenase-cyclohydrolases can rescue mthfd2 null fibroblasts.

  Archives of biochemistry and biophysics 20051001

• Pancreatic beta cells from db/db mice show cell-specific [Ca2+]i and NADH responses to glucose but not to alpha-ketoisocaproic acid.

  Pancreas 20051001

• Highly sensitive fluorimetic determination of gluthione based inhibitory effect on multienzyme redox system.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20051001

• Mitochondrial impairment induced by poly(ADP-ribose) polymerase-1 activation in cortical neurons after oxygen and glucose deprivation.

  Journal of neurochemistry 20051001

• Coordinated patterns of cytochrome bd and lactate dehydrogenase expression in Bacillus subtilis.

  Microbiology (Reading, England) 20051001

• Effect of pollen-mediated oxidative stress on immediate hypersensitivity reactions and late-phase inflammation in allergic conjunctivitis.

  The Journal of allergy and clinical immunology 20051001

• Molecular properties and enhancement of thermostability by random mutagenesis of glutamate dehydrogenase from Bacillus subtilis.

  Bioscience, biotechnology, and biochemistry 20051001

• Initiation of a superoxide-dependent chain oxidation of lactate dehydrogenase-bound NADH by oxidants of low and high reactivity.

  Free radical research 20051001

• Cloning and expression of NAD+-dependent L-arabinitol 4-dehydrogenase gene (ladA) of Aspergillus oryzae.

  Journal of bioscience and bioengineering 20051001

• Functional roles of ATP-binding residues in the catalytic site of human mitochondrial NAD(P)+-dependent malic enzyme.

  Biochemistry 20050927

• Deprotonation of the horse liver alcohol dehydrogenase-NAD+ complex controls formation of the ternary complexes.

  Biochemistry 20050927

• A filter plate-based assay for mono ADP-ribosyltransferases [corrected].

  Analytical biochemistry 20050915

• COQ9, a new gene required for the biosynthesis of coenzyme Q in Saccharomyces cerevisiae.

  The Journal of biological chemistry 20050909

• The human apoptosis-inducing protein AMID is an oxidoreductase with a modified flavin cofactor and DNA binding activity.

  The Journal of biological chemistry 20050902

• Age-associated decline in mitochondrial respiration and electron transport in Drosophila melanogaster.

  The Biochemical journal 20050901

• Expression of functionally phagocyte-type NAD(P)H oxidase in pericytes: effect of angiotensin II and high glucose.

  Biology of the cell 20050901

• Theoretical study of stereoselective reduction controlled by NADH analogs.

  Journal of molecular graphics & modelling 20050901

• The approach to the Michaelis complex in lactate dehydrogenase: the substrate binding pathway.

  Biophysical journal 20050901

• Physiological regulation of the properties of alcohol dehydrogenase II (ADH II) of Zymomonas mobilis: NADH renders ADH II resistant to cyanide and aeration.

  Archives of microbiology 20050901

• MonoADP-ribosylation of the NAD+-dependent alcohol dehydrogenase from Entamoeba histolytica.

  Current microbiology 20050901

• Interactions between melatonin and nicotinamide nucleotide: NADH preservation in cells and in cell-free systems by melatonin.

  Journal of pineal research 20050901

• Effect of calcium chloride, zinc chloride, and water infusion on metmyoglobin reducing activity and fresh lamb color.

  Journal of animal science 20050901

• High sensitivity of CD4+CD25+ regulatory T cells to extracellular metabolites nicotinamide adenine dinucleotide and ATP: a role for P2X7 receptors.

  Journal of immunology (Baltimore, Md. : 1950) 20050901

• Improved mitochondrial bioenergetics by anesthetic preconditioning during and after 2 hours of 27 degrees C ischemia in isolated hearts.

  Journal of cardiovascular pharmacology 20050901

• Mitochondria-driven changes in leaf NAD status exert a crucial influence on the control of nitrate assimilation and the integration of carbon and nitrogen metabolism.

  Plant physiology 20050901

• Structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum.

  Acta crystallographica. Section D, Biological crystallography 20050901

• The structure of a eukaryotic nicotinic acid phosphoribosyltransferase reveals structural heterogeneity among type II PRTases.

  Structure (London, England : 1993) 20050901

• Small molecule regulation of Sir2 protein deacetylases.

  The FEBS journal 20050901

• Increase in NADH-glutamate dehydrogenase activity by mercury in excised bean leaf segments.

  Indian journal of experimental biology 20050901

• Structures of NADH and CH3-H4folate complexes of Escherichia coli methylenetetrahydrofolate reductase reveal a spartan strategy for a ping-pong reaction.

  Biochemistry 20050830

• A novel strong competitive inhibitor of complex I.

  FEBS letters 20050829

• Disruption of the coenzyme binding site and dimer interface revealed in the crystal structure of mitochondrial aldehyde dehydrogenase 'Asian' variant.

  The Journal of biological chemistry 20050826

• Temperature-induced conformational change at the catalytic site of Sulfolobus solfataricus alcohol dehydrogenase highlighted by Asn249Tyr substitution. A hydrogen/deuterium exchange, kinetic, and fluorescence quenching study.

  Biochemistry 20050823

• Effect of inhibition of the bc1 complex on gene expression profile in yeast.

  The Journal of biological chemistry 20050819

• Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry.

  Nature 20050818

• Biomimetics with a self-assembled monolayer of catalytically active tethered isoalloxazine on Au.

  Langmuir : the ACS journal of surfaces and colloids 20050816

• Structural basis for the activation of cholera toxin by human ARF6-GTP.

  Science (New York, N.Y.) 20050812

• Chiral oxazolines and their legacy in asymmetric carbon-carbon bond-forming reactions.

  The Journal of organic chemistry 20050805

• Laminar flow-based electrochemical microreactor for efficient regeneration of nicotinamide cofactors for biocatalysis.

  Journal of the American Chemical Society 20050803

• The reductase of p-hydroxyphenylacetate 3-hydroxylase from Acinetobacter baumannii requires p-hydroxyphenylacetate for effective catalysis.

  Biochemistry 20050802

• Identification of cytochrome-b5 reductase as the enzyme responsible for NADH-dependent lucigenin chemiluminescence in human spermatozoa.

  Biology of reproduction 20050801

• Molecular dynamics simulation studies of the wild-type, I21V, and I16T mutants of isoniazid-resistant Mycobacterium tuberculosis enoyl reductase (InhA) in complex with NADH: toward the understanding of NADH-InhA different affinities.

  Biophysical journal 20050801

• Interflavin one-electron transfer in the inducible nitric oxide synthase reductase domain and NADPH-cytochrome P450 reductase.

  Archives of biochemistry and biophysics 20050801

• A modified consensus approach to mutagenesis inverts the cofactor specificity of Bacillus stearothermophilus lactate dehydrogenase.

  Protein engineering, design & selection : PEDS 20050801

• NADH can enter into astrocytes and block poly(ADP-ribose) polymerase-1-mediated astrocyte death.

  Neuroreport 20050801

• SIRT1 is critical regulator of FOXO-mediated transcription in response to oxidative stress.

  International journal of molecular medicine 20050801

• Assaying uridine diphosphoglucose dehydrogenase in the presence of alcohol dehydrogenase.

  Analytical biochemistry 20050801

• Mechanistic investigation of a highly active phosphite dehydrogenase mutant and its application for NADPH regeneration.

  The FEBS journal 20050801

• p53 proteasomal degradation: poly-ubiquitination is not the whole story.

  Cell cycle (Georgetown, Tex.) 20050801

• Microplate filtration assay for nicotinamide release from NAD using a boronic acid resin.

  Methods (San Diego, Calif.) 20050801

• Assays for mechanistic investigations of protein/histone acetyltransferases.

  Methods (San Diego, Calif.) 20050801

• In vitro assays for the determination of histone deacetylase activity.

  Methods (San Diego, Calif.) 20050801

• Benzamide and 4-amino 1,8 naphthalimide treatment inhibit telomerase activity by down-regulating the expression of telomerase associated protein and inhibiting the poly(ADP-ribosyl)ation of telomerase reverse transcriptase in cultured cells.

  The FEBS journal 20050801

• Tankyrase-1 overexpression reduces genotoxin-induced cell death by inhibiting PARP1.

  Molecular and cellular biochemistry 20050801

• Effects of electron transport inhibitors and uncouplers on the oxidation of ferrous iron and compounds interacting with ferric iron in Acidithiobacillus ferrooxidans.

  Canadian journal of microbiology 20050801

• [Mechanism study on difference of biotransformation between Mycobacterium fortuitum MF2 and MF96].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20050801

• [Cloning and analysis of genes encoding 2-naphthoate monooxygenase and NADH:flavin oxidoreductase].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20050801

• Botulinum neurotoxin types A, B, and E: fragmentations by autoproteolysis and other mechanisms including by O-phenanthroline-dithiothreitol, and association of the dinucleotides NAD(+)/NADH with the heavy chain of the three neurotoxins.

  The protein journal 20050801

• Role of active site residues and solvent in proton transfer and the modulation of flavin reduction potential in bacterial morphinone reductase.

  The Journal of biological chemistry 20050722

• Crystal structure of the NAD biosynthetic enzyme quinolinate synthase.

  The Journal of biological chemistry 20050722

• Targeting the NAD7 subunit to mitochondria restores a functional complex I and a wild type phenotype in the Nicotiana sylvestris CMS II mutant lacking nad7.

  The Journal of biological chemistry 20050715

• Understanding human 15-hydroxyprostaglandin dehydrogenase binding with NAD+ and PGE2 by homology modeling, docking and molecular dynamics simulation.

  Bioorganic & medicinal chemistry 20050715

• Nucleotide binding affinities of the intact proton-translocating transhydrogenase from Escherichia coli.

  Biochimica et biophysica acta 20050715

• Crystal structure of human dihydrolipoamide dehydrogenase: NAD+/NADH binding and the structural basis of disease-causing mutations.

  Journal of molecular biology 20050715

• Formation and characterization of glutamate dehydrogenase monolayers on silicon supports.

  Biosensors & bioelectronics 20050715

• Role of palladium in the redox electrochemistry of ferrocene monocarboxylic acid encapsulated within ORMOSIL networks.

  Molecules (Basel, Switzerland) 20050714

• Quinolinate synthetase, an iron-sulfur enzyme in NAD biosynthesis.

  FEBS letters 20050704

• Investigation of methaemoglobin reduction by extracellular NADH in mammalian erythrocytes.

  The international journal of biochemistry & cell biology 20050701

• Mechanism of the conversion of xanthine dehydrogenase to xanthine oxidase: identification of the two cysteine disulfide bonds and crystal structure of a non-convertible rat liver xanthine dehydrogenase mutant.

  The Journal of biological chemistry 20050701

• Structural transformations in the dynamics of Michaelis complex formation in lactate dehydrogenase.

  Biophysical journal 20050701

• The role of CO2 in cobalt-catalyzed peroxidations.

  Archives of biochemistry and biophysics 20050701

• Regulation of oxidative phosphorylation in intact mammalian heart in vivo.

  Biophysical chemistry 20050701

• Identification of ATP-NADH kinase isozymes and their contribution to supply of NADP(H) in Saccharomyces cerevisiae.

  The FEBS journal 20050701

• Flavin adenine dinucleotide as precursor for NADH electrocatalyst.

  Analytical chemistry 20050701

• Oxidative stress is involved in the permeabilization of the inner membrane of brain mitochondria exposed to hypoxia/reoxygenation and low micromolar Ca2+.

  The FEBS journal 20050701

• Structure and function of poly(ADP-ribose) polymerase-1: role in oxidative stress-related pathologies.

  Current vascular pharmacology 20050701

• Effect of pressure on nucleotide binding to yeast alcohol dehydrogenase.

  Protein and peptide letters 20050701

• Enzymatic sensitivity enhancement of biogenic monoamines on a chip.

  Electrophoresis 20050701

• Short-term regulation of the alpha-ketoglutarate dehydrogenase complex by energy-linked and some other effectors.

  Biochemistry. Biokhimiia 20050701

• Complete reversal of coenzyme specificity of isocitrate dehydrogenase from Haloferax volcanii.

  The protein journal 20050701

• Effect of different levels of NADH availability on metabolic fluxes of Escherichia coli chemostat cultures in defined medium.

  Journal of biotechnology 20050629

• Shape and color of au nanoparticles follow biocatalytic processes.

  Langmuir : the ACS journal of surfaces and colloids 20050621

• Activation of isolated NADH:ubiquinone reductase I (complex I) from Escherichia coli by detergent and phospholipids. Recovery of ubiquinone reductase activity and changes in EPR signals of iron-sulfur clusters.

  Biochemistry 20050614

• The molecular architecture of galactose mutarotase/UDP-galactose 4-epimerase from Saccharomyces cerevisiae.

  The Journal of biological chemistry 20050610

• Differential effects of Mg2+ ions on the individual kinetic steps of human cytosolic and mitochondrial aldehyde dehydrogenases.

  Biochemistry 20050607

• Properties of polyaniline/carbon nanotube multilayer films in neutral solution and their application for stable low-potential detection of reduced beta-nicotinamide adenine dinucleotide.

  Langmuir : the ACS journal of surfaces and colloids 20050607

• Identification of key amino acids responsible for the substantially higher affinities of human type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD1) for substrates, coenzymes, and inhibitors relative to human 3beta-HSD2.

  The Journal of biological chemistry 20050603

• Application of cyanide hydrolase from Klebsiella sp. in a biosensor system for the detection of low-level cyanide.

  Applied microbiology and biotechnology 20050601

• Cytosolic NADH redox and thiol oxidation regulate pulmonary arterial force through ERK MAP kinase.

  American journal of physiology. Lung cellular and molecular physiology 20050601

• The glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase works as an arsenate reductase in human red blood cells and rat liver cytosol.

  Toxicological sciences : an official journal of the Society of Toxicology 20050601

• Reduction of arsenate to arsenite by human erythrocyte lysate and rat liver cytosol - characterization of a glutathione- and NAD-dependent arsenate reduction linked to glycolysis.

  Toxicological sciences : an official journal of the Society of Toxicology 20050601

• Multiple proteins with single activities or a single protein with multiple activities: the conundrum of cell surface NADH oxidoreductases.

  Biochimica et biophysica acta 20050601

• Mechanism and applications of phosphite dehydrogenase.

  Bioorganic chemistry 20050601

• Pyruvate but not lactate prevents NADH-induced myoglobin oxidation.

  Free radical biology & medicine 20050601

• Polymorphisms in the mitochondrial aldehyde dehydrogenase gene (Aldh2) determine peak blood acetaldehyde levels and voluntary ethanol consumption in rats.

  Pharmacogenetics and genomics 20050601

• Glycolytic oscillations and waves in an open spatial reactor: Impact of feedback regulation of phosphofructokinase.

  Biophysical chemistry 20050601

• Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid).

  Clinica chimica acta; international journal of clinical chemistry 20050601

• On the mechanisms of glycolytic oscillations in yeast.

  The FEBS journal 20050601

• Adventitious reactions of alkene monooxygenase reveal common reaction pathways and component interactions among bacterial hydrocarbon oxygenases.

  The FEBS journal 20050601

• Substrate kinetics of the Acanthamoeba castellanii alternative oxidase and the effects of GMP.

  Biochimica et biophysica acta 20050601

• Recessive congenital methaemoglobinaemia: functional characterization of the novel D239G mutation in the NADH-binding lobe of cytochrome b5 reductase.

  British journal of haematology 20050601

• Effect of adriamycin treatment on the lifetime of pyrene butyric acid in single living cells.

  Free radical research 20050601

• Relationship between immune status and activity of the lymphocyte energy supply system in adolescents suffering from frequent diseases.

  Bulletin of experimental biology and medicine 20050601

• Crystallization and avoiding the problem of hemihedral twinning in crystals of Delta1-pyrroline-5-carboxylate dehydrogenase from Thermus thermophilus.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20050601

• Structural studies on 3-hydroxyanthranilate-3,4-dioxygenase: the catalytic mechanism of a complex oxidation involved in NAD biosynthesis.

  Biochemistry 20050531

• Glucose suppresses superoxide generation in metabolically responsive pancreatic beta cells.

  The Journal of biological chemistry 20050527

• Characterization of a new pantothenate kinase isoform from Helicobacter pylori.

  The Journal of biological chemistry 20050527

• Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation.

  Cell 20050520

• A spectrophotometric assay for the determination of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase activity.

  Analytical biochemistry 20050515

• Aspartate 120 of Escherichia coli methylenetetrahydrofolate reductase: evidence for major roles in folate binding and catalysis and a minor role in flavin reactivity.

  Biochemistry 20050510

• Nicotinic acid limitation regulates silencing of Candida adhesins during UTI.

  Science (New York, N.Y.) 20050506

• Inhibition and pH dependence of phosphite dehydrogenase.

  Biochemistry 20050503

• Characterization of oxidized nicotinamide adenine dinucleotide (NAD(+)) analogues using a high-pressure-liquid-chromatography-based NAD(+)-glycohydrolase assay and comparison with fluorescence-based measurements.

  Analytical biochemistry 20050501

• CtBP represses p300-mediated transcriptional activation by direct association with its bromodomain.

  Nature structural & molecular biology 20050501

• The sources of oxidative stress in the vessel wall.

  Kidney international 20050501

• Involvement of mitochondria in myasthenia gravis complicated with dermatomyositis and rheumatoid arthritis: a case report.

  Acta neuropathologica 20050501

• The Calvin cycle in cyanobacteria is regulated by CP12 via the NAD(H)/NADP(H) ratio under light/dark conditions.

  The Plant journal : for cell and molecular biology 20050501

• Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050501

• Poly(ADP-ribose) polymerase-1 could facilitate the religation of topoisomerase I-linked DNA inhibited by camptothecin.

  Cancer research 20050501

• Hitting transcription in all the right places.

  Nature structural & molecular biology 20050501

• Characterization of 11beta-hydroxysteroid dehydrogenase activity in testicular tissue of control and GnRH-immunized boars as a possible regulator of spermatogenesis.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20050501

• Periodic fluctuations in oxygen consumption comparing HeLa (cancer) and CHO (non-cancer) cells and response to external NAD(P)+/NAD(P)H.

  Molecular and cellular biochemistry 20050501

• Xanthine oxidase catalyzes anaerobic transformation of organic nitrates to nitric oxide and nitrosothiols: characterization of this mechanism and the link between organic nitrate and guanylyl cyclase activation.

  The Journal of biological chemistry 20050429

• A mitochondrial NADH-dependent fumarate reductase involved in the production of succinate excreted by procyclic Trypanosoma brucei.

  The Journal of biological chemistry 20050429

• Crystal structure of a novel shikimate dehydrogenase from Haemophilus influenzae.

  The Journal of biological chemistry 20050429

• DNA detection through signal amplification by using NADH: flavin oxidoreductase and oligonucleotide-flavin conjugates as cofactors.

  Angewandte Chemie (International ed. in English) 20050429

• Crystal structure of the RNA 2'-phosphotransferase from Aeropyrum pernix K1.

  Journal of molecular biology 20050429

• Scale-rich metabolic networks.

  Physical review letters 20050429

• pH-dependent substrate preference of pig heart lipoamide dehydrogenase varies with oligomeric state: response to mitochondrial matrix acidification.

  The Journal of biological chemistry 20050422

• SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}.

  The Journal of biological chemistry 20050422

• Structures of Escherichia coli NAD synthetase with substrates and products reveal mechanistic rearrangements.

  The Journal of biological chemistry 20050415

• Log P effect of organic solvents on a thermophilic alcohol dehydrogenase.

  Biochimica et biophysica acta 20050415

• 5-Hydroxytryptophan as a precursor of a catalyst for the oxidation of NADH.

  Analytical chemistry 20050415

• Formation of soluble organo-chromium(III) complexes after chromate reduction in the presence of cellular organics.

  Environmental science & technology 20050415

• Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.

  The Journal of biological chemistry 20050408

• Human endothelial nitric oxide synthase gene delivery protects against cardiac remodeling and reduces oxidative stress after myocardial infarction.

  Life sciences 20050408

• Oxidations of NADH analogues by cis-[RuIV(bpy)2(py)(O)]2+ occur by hydrogen-atom transfer rather than by hydride transfer.

  Inorganic chemistry 20050404

• Robust NADH-regenerator: improved alpha-haloketone-resistant formate dehydrogenase.

  Applied microbiology and biotechnology 20050401

• Hydrogen peroxide production by Mycoplasma bovis and Mycoplasma agalactiae and effect of in vitro passage on a Mycoplasma bovis strain producing high levels of H2O2.

  Veterinary research communications 20050401

• Porin and cytochrome oxidase containing contact sites involved in the oxidation of cytosolic NADH.

  Archives of biochemistry and biophysics 20050401

• Functional characterizations of novWUS involved in novobiocin biosynthesis from Streptomyces spheroides.

  Archives of biochemistry and biophysics 20050401

• Electrocatalytic oxidation of NADH at single-wall carbon-nanotube-paste electrodes: kinetic considerations for use of a redox mediator in solution and dissolved in the paste.

  Analytical and bioanalytical chemistry 20050401

• Stereospecificity of hydride transfer in NAD+-catalyzed 2-deoxy-scyllo-inosose synthase, the key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminocyclitol antibiotics.

  Bioorganic chemistry 20050401

• Training of yeast cell dynamics.

  The FEBS journal 20050401

• A role for alcohol dehydrogenase in the Drosophila immune response?

  Insect molecular biology 20050401

• Effective NADH-dependent oxidation of 7beta-hydroxy-delta8-tetrahydrocannabinol to the corresponding ketone by Japanese monkey hepatic microsomes.

  Biological & pharmaceutical bulletin 20050401

• Structure of zinc-independent sorbitol dehydrogenase from Rhodobacter sphaeroides at 2.4 A resolution.

  Acta crystallographica. Section D, Biological crystallography 20050401

• Kupffer cell ablation improves hepatic microcirculation after trauma and sepsis.

  The Journal of trauma 20050401

• Tryptophan-NAD+ pathway metabolites as putative biomarkers and predictors of peroxisome proliferation.

  Archives of toxicology 20050401

• Purification and cDNA cloning of chloroplastic monodehydroascorbate reductase from spinach.

  Bioscience, biotechnology, and biochemistry 20050401

• Oxidase reaction of the hybrid Mn-peroxidase of the fungus Panus tigrinus 8/18.

  Biochemistry. Biokhimiia 20050401

• Trypanocidal activity of N-isopropyl oxamate on cultured epimastigotes and murine trypanosomiasis using different Trypanosoma cruzi strains.

  Journal of enzyme inhibition and medicinal chemistry 20050401

• [Study on multi-photon excited fluorescence combined with capillary electrophoresis].

  Guang pu xue yu guang pu fen xi = Guang pu 20050401

• Effect of co-existing biologically relevant molecules and ions on DNA photocleavage caused by pyrene and its derivatives.

  International journal of environmental research and public health 20050401

• Reduction in the E2k subunit of the alpha-ketoglutarate dehydrogenase complex has effects independent of complex activity.

  The Journal of biological chemistry 20050325

• Probing the mechanism of the Archaeoglobus fulgidus inositol-1-phosphate synthase.

  The Journal of biological chemistry 20050325

• Synthesis of arabinitol 1-phosphate and its use for characterization of arabinitol-phosphate dehydrogenase.

  Carbohydrate research 20050321

• Complete reversal of coenzyme specificity of xylitol dehydrogenase and increase of thermostability by the introduction of structural zinc.

  The Journal of biological chemistry 20050318

• SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1.

  The Journal of biological chemistry 20050318

• Breakdown of 2-hydroxylated straight chain fatty acids via peroxisomal 2-hydroxyphytanoyl-CoA lyase: a revised pathway for the alpha-oxidation of straight chain fatty acids.

  The Journal of biological chemistry 20050318

• Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme.

  Molecular cell 20050318

• PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation.

  Oncogene 20050317

• CD38 controls ADP-ribosyltransferase-2-catalyzed ADP-ribosylation of T cell surface proteins.

  Journal of immunology (Baltimore, Md. : 1950) 20050315

• Lower induction of p53 and decreased apoptosis in NQO1-null mice lead to increased sensitivity to chemical-induced skin carcinogenesis.

  Cancer research 20050315

• A catalytic triad is responsible for acid-base chemistry in the Ascaris suum NAD-malic enzyme.

  Biochemistry 20050308

• Effect of oxygen on the Escherichia coli ArcA and FNR regulation systems and metabolic responses.

  Biotechnology and bioengineering 20050305

• Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1.

  Nature 20050303

• Cutaneous metabolism of glycol ethers.

  Archives of toxicology 20050301

• Mode of mutagenic action for the biocide Bioban CS-1246 in mouse lymphoma cells and implications for its in vivo mutagenic potential.

  Toxicological sciences : an official journal of the Society of Toxicology 20050301

• Redox properties of the lipocalin alpha1-microglobulin: reduction of cytochrome c, hemoglobin, and free iron.

  Free radical biology & medicine 20050301

• Fundamental differences in bioaffinity of amino acid dehydrogenases for N6- and S6-linked immobilized cofactors using kinetic-based enzyme-capture strategies.

  Analytical biochemistry 20050301

• Determination of oxidized and reduced nicotinamide adenine dinucleotide in cell monolayers using a single extraction procedure and a spectrophotometric assay.

  Analytical biochemistry 20050301

• Discovery and characterization of a Coenzyme A disulfide reductase from Pyrococcus horikoshii. Implications for this disulfide metabolism of anaerobic hyperthermophiles.

  The FEBS journal 20050301

• Properties of the thermostable glutamate dehydrogenase of the mesophilic anaerobe Peptostreptoccus asaccharolyticus purified by a novel method after over-expression in an Escherichia coli host.

  FEMS microbiology letters 20050301

• Cerebral oxidative stress and depression of energy metabolism correlate with severity of diffuse brain injury in rats.

  Neurosurgery 20050301

• Alpha-crystallin: an ATP-independent complete molecular chaperone toward sorbitol dehydrogenase.

  Cellular and molecular life sciences : CMLS 20050301

• Gluconobacter oxydans NAD-dependent, D-fructose reducing, polyol dehydrogenases activity: screening, medium optimisation and application for enzymatic polyol production.

  Biotechnology letters 20050301

• Rational proteomics IV: modeling the primary function of the mammalian 17beta-hydroxysteroid dehydrogenase type 8.

  The Journal of steroid biochemistry and molecular biology 20050301

• Possible involvement of glutamic and/or aspartic acid residue(s) and requirement of mitochondrial integrity for the protective effect of creatine against inhibition of cardiac mitochondrial respiration by methylglyoxal.

  Molecular and cellular biochemistry 20050301

• Critical role of the cysteine 323 residue in the catalytic activity of human glutamate dehydrogenase isozymes.

  Molecules and cells 20050227

• The selective cause of an ancient adaptation.

  Science (New York, N.Y.) 20050225

• Electrochemical sensing platform based on the carbon nanotubes/redox mediators-biopolymer system.

  Journal of the American Chemical Society 20050223

• Characterization of a cloned temperature-sensitive construct of the diphtheria toxin A domain.

  Biochemistry 20050222

• Studies on the 4-benzoylpyridine-3-carboxamide entity as a fragment model of the Isoniazid-NAD adduct.

  Organic & biomolecular chemistry 20050221

• 1H and 13C NMR characterization of pyridinium-type isoniazid-NAD adducts as possible inhibitors of InhA reductase of Mycobacterium tuberculosis.

  Organic & biomolecular chemistry 20050221

• Histidine 129 in the 75-kDa subunit of mitochondrial complex I from Yarrowia lipolytica is not a ligand for [Fe4S4] cluster N5 but is required for catalytic activity.

  The Journal of biological chemistry 20050218

• Conformational diversity in NAD(H) and interacting transhydrogenase nicotinamide nucleotide binding domains.

  Journal of molecular biology 20050218

• Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition.

  Molecular cell 20050218

• Development of a commercial amperometric biosensor electrode for the ketone D-3-hydroxybutyrate.

  Biosensors & bioelectronics 20050215

• P2X7 receptor-dependent and -independent T cell death is induced by nicotinamide adenine dinucleotide.

  Journal of immunology (Baltimore, Md. : 1950) 20050215

• Mechanistic aspects of the deoxyribonuclease activity of diphtheria toxin.

  Biochimica et biophysica acta 20050214

• Exposure to hypoxia rapidly induces mitochondrial channel activity within a living synapse.

  The Journal of biological chemistry 20050211

• Mitochondrial trans-2-enoyl-CoA reductase of wax ester fermentation from Euglena gracilis defines a new family of enzymes involved in lipid synthesis.

  The Journal of biological chemistry 20050211

• Kinetic properties and metabolic contributions of yeast mitochondrial and cytosolic NADP+-specific isocitrate dehydrogenases.

  The Journal of biological chemistry 20050211

• The high-resolution Structure of LeuB (Rv2995c) from Mycobacterium tuberculosis.

  Journal of molecular biology 20050211

• Formation of an oxo-radical of peroxovanadate during reduction of diperoxovanadate with vanadyl sulfate or ferrous sulfate.

  Biochimica et biophysica acta 20050211

• Peptide antibiotic and actin-binding protein as mixed-type inhibitors of Clostridium difficile CDT toxin activities.

  Biochemical and biophysical research communications 20050204

• A novel NADPH:(bound) NADP+ reductase and NADH:(bound) NADP+ transhydrogenase function in bovine liver catalase.

  The Biochemical journal 20050201

• Differential regulation of voltage-gated K+ channels by oxidized and reduced pyridine nucleotide coenzymes.

  American journal of physiology. Cell physiology 20050201

• Chronic exposure to beta-hydroxybutyrate inhibits glucose-induced insulin release from pancreatic islets by decreasing NADH contents.

  American journal of physiology. Endocrinology and metabolism 20050201

• Development of a simple and efficient method for assaying cytidine monophosphate sialic acid synthetase activity using an enzymatic reduced nicotinamide adenine dinucleotide/oxidized nicotinamide adenine dinucleotide converting system.

  Analytical biochemistry 20050201

• Altered NADH/NAD+ ratio mediates coresistance to isoniazid and ethionamide in mycobacteria.

  Antimicrobial agents and chemotherapy 20050201

• Inositol 1,4,5-trisphosphate receptor/GAPDH complex augments Ca2+ release via locally derived NADH.

  Proceedings of the National Academy of Sciences of the United States of America 20050201

• Competing roles of cytochrome P450 1A1/1B1 and aldo-keto reductase 1A1 in the metabolic activation of (+/-)-7,8-dihydroxy-7,8-dihydro-benzo[a]pyrene in human bronchoalveolar cell extracts.

  Chemical research in toxicology 20050201

• Alternative splicing generates a CaM kinase IIbeta isoform in myocardium that targets the sarcoplasmic reticulum through a putative alphaKAP and regulates GAPDH.

  Molecular and cellular biochemistry 20050201

• NAD deamidation 'a new reaction' by an enzyme from Aspergillus terreus DSM 826.

  Antonie van Leeuwenhoek 20050201

• Generation of superoxide-radical by the NADH:ubiquinone oxidoreductase of heart mitochondria.

  Biochemistry. Biokhimiia 20050201

• Inhibition by N'-nitrosonornicotine of the catalytic activity of glutamate dehydrogenase in alpha-ketoglutarate amination.

  Journal of enzyme inhibition and medicinal chemistry 20050201

• Optical and electrochemical detection of NADH and of NAD+-dependent biocatalyzed processes by the catalytic deposition of copper on gold nanoparticles.

  Small (Weinheim an der Bergstrasse, Germany) 20050201

• Fine tuning of coenzyme specificity in family 2 aldo-keto reductases revealed by crystal structures of the Lys-274-->Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD+ and NADP+.

  FEBS letters 20050131

• Synthesis and antiviral evaluation of cis-substituted cyclohexenyl and cyclohexanyl nucleosides.

  Journal of medicinal chemistry 20050127

• The pyridine ring of NAD is formed by a nonenzymatic pericyclic reaction.

  Journal of the American Chemical Society 20050126

• Drosophila alcohol dehydrogenase: acetate-enzyme interactions and novel insights into the effects of electrostatics on catalysis.

  Journal of molecular biology 20050121

• 5-Hydroxydecanoate is metabolised in mitochondria and creates a rate-limiting bottleneck for beta-oxidation of fatty acids.

  The Journal of physiology 20050115

• Key NAD+-binding residues in human 15-hydroxyprostaglandin dehydrogenase.

  Archives of biochemistry and biophysics 20050115

• Non-invasive live-cell measurement of changes in macrophage NAD(P)H by two-photon microscopy.

  Immunology letters 20050115

• The first crystal structure of hyperthermostable NAD-dependent glutamate dehydrogenase from Pyrobaculum islandicum.

  Journal of molecular biology 20050114

• Molecular switch based on a biologically important redox reaction.

  The journal of physical chemistry. B 20050113

• Diabetic retinopathy mechanism probed.

  JAMA 20050112

• Selective complexation of N-alkylpyridinium salts: binding of NAD+ in water.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20050107

• P/O ratios of mitochondrial oxidative phosphorylation.

  Biochimica et biophysica acta 20050107

• The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallography.

  The Biochemical journal 20050101

• Identification, molecular cloning and functional characterization of a novel NADH kinase from Arabidopsis thaliana (thale cress).

  The Biochemical journal 20050101

• ADP-ribosylation of integrin alpha7 modulates the binding of integrin alpha7beta1 to laminin.

  The Biochemical journal 20050101

• Effect of oxidative stress on in vivo ADP-ribosylation of eukaryotic elongation factor 2.

  The international journal of biochemistry & cell biology 20050101

• Control of glycolytic oscillations by temperature.

  Biophysical journal 20050101

• NAD+ as a metabolic link between DNA damage and cell death.

  Journal of neuroscience research 20050101

• Effects of pressure on deuterium isotope effects of yeast alcohol dehydrogenase using alternative substrates.

  Archives of biochemistry and biophysics 20050101

• Structure-function analysis of the yeast NAD+-dependent tRNA 2'-phosphotransferase Tpt1.

  RNA (New York, N.Y.) 20050101

• Uncoupling of nutrient metabolism from insulin secretion by overexpression of cytosolic phospholipase A(2).

  Diabetes 20050101

• Anesthetic preconditioning: the role of free radicals in sevoflurane-induced attenuation of mitochondrial electron transport in Guinea pig isolated hearts.

  Anesthesia and analgesia 20050101

• Complex I regulates mutant mitochondrial aldehyde dehydrogenase activity and voluntary ethanol consumption in rats.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050101

• Inhibition of Nox-4 activity by plumbagin, a plant-derived bioactive naphthoquinone.

  The Journal of pharmacy and pharmacology 20050101

• X-ray structure of a Rex-family repressor/NADH complex insights into the mechanism of redox sensing.

  Structure (London, England : 1993) 20050101

• Electron transfer ability from NADH to menaquinone and from NADPH to oxygen of type II NADH dehydrogenase of Corynebacterium glutamicum.

  Bioscience, biotechnology, and biochemistry 20050101

• Increasing fat in the diet does not improve muscle performance in patients with mitochondrial myopathy due to complex I deficiency.

  Journal of inherited metabolic disease 20050101

• Tert-butyl hydroperoxide selectively inhibits mitochondrial respiratory-chain enzymes in isolated rat hepatocytes.

  Physiological research 20050101

• Inhibitory effects of flavonoids on the reduction of progesterone to 20alpha-hydroxyprogesterone in rat liver.

  The Journal of steroid biochemistry and molecular biology 20050101

• [Stable isotopes of Mg2+ as activators of the suppressed ATP-generating function of mitochondria].

  Biofizika 20050101

• Data mining of the transcriptome of Plasmodium falciparum: the pentose phosphate pathway and ancillary processes.

  Malaria journal 20050101

• In vivo multiparametric monitoring of brain functions under intracranial hypertension following mannitol administration.

  Neurological research 20050101

• [Study on the effect of aluminum (III) on NADH in the presence of NH4Ac in aqueous solution].

  Guang pu xue yu guang pu fen xi = Guang pu 20050101

• MT FdR: a ferredoxin reductase from M. tuberculosis that couples to MT CYP51.

  Biochimica et biophysica acta 20050101

• NAD(H) enhances the Cu(II)-mediated inactivation of lactate dehydrogenase by increasing the accessibility of sulfhydryl groups.

  Free radical research 20050101

• Study on the effect of thiamine on the metabolism of yeast by intrinsic fluorescence.

  Luminescence : the journal of biological and chemical luminescence 20050101

• Oxidative stress mediated idiosyncratic drug toxicity.

  Drug metabolism reviews 20050101

• Effect of carvedilol on neuronal survival and poly(ADP-ribose) polymerase activity in hippocampus after transient forebrain ischemia.

  Acta neurobiologiae experimentalis 20050101

• Enzyme-assisted reforming of glucose to hydrogen in a photoelectrochemical cell.

  Photochemistry and photobiology 20050101

• Direct transfer of NADH from malate dehydrogenase to complex I in Escherichia coli.

  Cell biochemistry and biophysics 20050101

• The purine nucleotide content in human leukemia cell lines.

  Cellular & molecular biology letters 20050101

• Effect of oxygen on the dehalogenation of 1,2-Dibromo-3-chloropropane by cytochrome P450cam (CYP101).

  Biotechnology progress 20050101

• Enzymatic redox cofactor regeneration in organic media: functionalization and application of glycerol dehydrogenase and soluble transhydrogenase in reverse micelles.

  Biotechnology progress 20050101

• Effect of NAD on recovery of adenine nucleotide pool, phosphorylation potential, and stimulation of apoptosis during late period of reperfusion damage to myocardium.

  Bulletin of experimental biology and medicine 20050101

• [Ethanol metabolism in the yeasts Yarrowia and Torulopsis (a review)].

  Prikladnaia biokhimiia i mikrobiologiia 20050101

• The role of the carboxamide group in nicotinamide adenine dinucleotide in relation to hydride transfer: the reduced form of the dinucleotide as remedy in the modulation of neurotransmission.

  Nucleosides, nucleotides & nucleic acids 20050101

• Reactive oxygen species in spermatozoa: methods for monitoring and significance for the origins of genetic disease and infertility.

  Reproductive biology and endocrinology : RB&E 20050101

• Deactivation of formate dehydrogenase (FDH) in solution and at gas-liquid interfaces.

  Biotechnology progress 20050101

• A continuous, regenerative coupled GTPase assay for dynamin-related proteins.

  Methods in enzymology 20050101

• [Dependence of Ca2+ release from intracellular stores on NADH and FAD levels in fertilized and unfertilized bovine oocytes].

  Tsitologiia 20050101

• NAD+/NADH and/or CoQ/CoQH2 ratios from plasma membrane electron transport may determine ceramide and sphingosine-1-phosphate levels accompanying G1 arrest and apoptosis.

  BioFactors (Oxford, England) 20050101

• Stepwise functionalization of ribonucleopeptide complexes to receptors and sensors.

  Nucleic acids symposium series (2004) 20050101

• Peroxidase catalysed formation of cytotoxic prooxidant phenothiazine free radicals at physiological pH.

  Chemico-biological interactions 20041230

• Dehydrogenation versus oxygenation in two-electron and four-electron reduction of dioxygen by 9-alkyl-10-methyl-9,10-dihydroacridines catalyzed by monomeric cobalt porphyrins and cofacial dicobalt porphyrins in the presence of perchloric acid.

  Journal of the American Chemical Society 20041229

• Biosynthesis of colitose: expression, purification, and mechanistic characterization of GDP-4-keto-6-deoxy-D-mannose-3-dehydrase (ColD) and GDP-L-colitose synthase (ColC).

  Biochemistry 20041228

• Biochemical regulation of mammalian AMP-activated protein kinase activity by NAD and NADH.

  The Journal of biological chemistry 20041217

• NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1.

  Cell 20041217

• Immobilized cofactor derivatives for kinetic-based enzyme capture strategies: direct coupling of NAD(P)+.

  Analytical biochemistry 20041215

• Characterization of a new member of the flavoprotein disulfide reductase family of enzymes from Mycobacterium tuberculosis.

  The Journal of biological chemistry 20041210

• Metabolic activation of carcinogenic ethylbenzene leads to oxidative DNA damage.

  Chemico-biological interactions 20041207

• The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells.

  The Journal of biological chemistry 20041203

• Age-related compensatory activation of pyruvate dehydrogenase complex in rat heart.

  Biochemical and biophysical research communications 20041203

• Neurospora crassa CyPBP37: a cytosolic stress protein that is able to replace yeast Thi4p function in the synthesis of vitamin B1.

  Journal of molecular biology 20041203

• Functional properties of the alternative NADH:ubiquinone oxidoreductase from E. coli through comparative 3-D modelling.

  FEBS letters 20041203

• The action of oxygen on chlorophyll fluorescence quenching and absorption spectra in pea thylakoid membranes under the steady-state conditions.

  Journal of photochemistry and photobiology. B, Biology 20041202

• Trichomonas hydrogenosomes contain the NADH dehydrogenase module of mitochondrial complex I.

  Nature 20041202

• A candidate NAD+ transporter in an intracellular bacterial symbiont related to Chlamydiae.

  Nature 20041202

• The effect of rotenone on the urinary ethanol cycle in rats fed ethanol intragastrically.

  Experimental and molecular pathology 20041201

• Evaluation of enzymatic assays and compounds affecting ATP production in mitochondrial respiratory chain complex I deficiency.

  Analytical biochemistry 20041201

• Indirect electrochemical reduction of nicotinamide coenzymes.

  Bioelectrochemistry (Amsterdam, Netherlands) 20041201

• Bcl-2 family proteins regulate mitochondrial reactive oxygen production and protect against oxidative stress.

  Free radical biology & medicine 20041201

• Bacterial redox sensors.

  Nature reviews. Microbiology 20041201

• Leukemia inhibitory factor reduces contractile function and induces alterations in energy metabolism in isolated cardiomyocytes.

  Journal of molecular and cellular cardiology 20041201

• Modelling bound ligands in protein crystal structures.

  Acta crystallographica. Section D, Biological crystallography 20041201

• Analysis of bacterial glucose dehydrogenase homologs from thermoacidophilic archaeon Thermoplasma acidophilum: finding and characterization of aldohexose dehydrogenase.

  Bioscience, biotechnology, and biochemistry 20041201

• Regulation of NAD(+)-dependent isocitrate dehydrogenase in the citrate producing yeast Yarrowia lipolytica.

  Biochemistry. Biokhimiia 20041201

• Autocrine and paracrine calcium signaling by the CD38/NAD+/cyclic ADP-ribose system.

  Annals of the New York Academy of Sciences 20041201

• Hypoxia/anoxia as signaling for increased alcohol dehydrogenase activity in saffron (Crocus sativus L.) corm.

  Annals of the New York Academy of Sciences 20041201

• Purine nucleotides and their metabolites in erythrocytes of streptozotocin diabetic rats.

  Diabetes & metabolism 20041201

• [Molecular basis of citrin deficiency].

  Seikagaku. The Journal of Japanese Biochemical Society 20041201

• Conversion ratio of tryptophan to niacin in Japanese women fed a purified diet conforming to the Japanese Dietary Reference Intakes.

  Journal of nutritional science and vitaminology 20041201

• [The decrease of the activity of electron transfer chain of Torulopsis glabrata enhanced pyruvate productivity].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20041201

• Enzymatic properties of the membrane-bound NADH oxidase system in the aerobic respiratory chain of Bacillus cereus.

  Journal of biochemistry and molecular biology 20041130

• Impaired tricarboxylic acid cycle activity in mouse livers lacking cytosolic phosphoenolpyruvate carboxykinase.

  The Journal of biological chemistry 20041119

• Release of beta-nicotinamide adenine dinucleotide upon stimulation of postganglionic nerve terminals in blood vessels and urinary bladder.

  The Journal of biological chemistry 20041119

• Ornithine cyclodeaminase: structure, mechanism of action, and implications for the mu-crystallin family.

  Biochemistry 20041109

• The novel pathway for ketodiene oxylipin biosynthesis in Jerusalem artichoke (Helianthus tuberosus) tubers.

  Biochimica et biophysica acta 20041108

• Human myeloperoxidase catalyzes an oscillating peroxidase-oxidase reaction.

  Archives of biochemistry and biophysics 20041101

• Detection of hydrogen peroxide with Amplex Red: interference by NADH and reduced glutathione auto-oxidation.

  Archives of biochemistry and biophysics 20041101

• Oral streptococcal glyceraldehyde-3-phosphate dehydrogenase mediates interaction with Porphyromonas gingivalis fimbriae.

  Microbes and infection 20041101

• A possible link between skeletal muscle mitochondrial efficiency and age-induced insulin resistance.

  Diabetes 20041101

• Interactions between hyperglycemia and hypoxia: implications for diabetic retinopathy.

  Diabetes 20041101

• Inhibition of cardiac mitochondrial respiration by salicylic acid and acetylsalicylate.

  Journal of cardiovascular pharmacology 20041101

• The ND1 gene of complex I is a mutational hot spot for Leber's hereditary optic neuropathy.

  Annals of neurology 20041101

• The rat liver peroxisomal membrane forms a permeability barrier for cofactors but not for small metabolites in vitro.

  Journal of cell science 20041101

• Cadmium toxicity induced changes in nitrogen management in Lycopersicon esculentum leading to a metabolic safeguard through an amino acid storage strategy.

  Plant & cell physiology 20041101

• Role of inhibitor aliphatic chain in the thermodynamics of inhibitor binding to Escherichia coli enoyl-ACP reductase and the Phe203Leu mutant: a proposed mechanism for drug resistance.

  Biochemistry 20041026

• Pyruvate dehydrogenase kinase isoform 2 activity stimulated by speeding up the rate of dissociation of ADP.

  Biochemistry 20041026

• The human TAZ gene complements mitochondrial dysfunction in the yeast taz1Delta mutant. Implications for Barth syndrome.

  The Journal of biological chemistry 20041022

• Repair of oxidized iron-sulfur clusters in Escherichia coli.

  The Journal of biological chemistry 20041022

• Global position and recruitment of HATs and HDACs in the yeast genome.

  Molecular cell 20041022

• Analysis of in vivo kinetics of glycolysis in aerobic Saccharomyces cerevisiae by application of glucose and ethanol pulses.

  Biotechnology and bioengineering 20041020

• DNA cleavage induced by thermal electron transfer from a dimeric NADH analogue to acridinium ions in the presence of oxygen.

  Journal of the American Chemical Society 20041013

• Aminobacter aminovorans NADH:flavin oxidoreductase His140: a highly conserved residue critical for NADH binding and utilization.

  Biochemistry 20041012

• A mechanism of sulfite neurotoxicity: direct inhibition of glutamate dehydrogenase.

  The Journal of biological chemistry 20041008

• Catalase-peroxidases (KatG) exhibit NADH oxidase activity.

  The Journal of biological chemistry 20041008

• A disorder to order transition accompanies catalysis in retinaldehyde dehydrogenase type II.

  The Journal of biological chemistry 20041008

• Structural basis for the variation in triclosan affinity to enoyl reductases.

  Journal of molecular biology 20041008

• Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin.

  Molecular cell 20041008

• Alterations in glucose metabolism by cyclosporine in rat brain slices link to oxidative stress: interactions with mTOR inhibitors.

  British journal of pharmacology 20041001

• Escherichia coli Hmp, an 'oxygen-binding flavohaemoprotein', produces superoxide anion and self-destructs.

  Archives of microbiology 20041001

• F420H2 oxidase (FprA) from Methanobrevibacter arboriphilus, a coenzyme F420-dependent enzyme involved in O2 detoxification.

  Archives of microbiology 20041001

• Overproduction of NAD+ and 5'-inosine monophosphate in the presence of 10 microM Mn2+ by a mutant of Corynebacterium ammoniagenes with thermosensitive nucleotide reduction (nrd(ts)) after temperature shift.

  Archives of microbiology 20041001

• High-performance liquid chromatography-based methods of enzymatic analysis: electron transport chain activity in mitochondria from human skeletal muscle.

  Analytical biochemistry 20041001

• Expanding the phenotype of potassium channelopathy: severe neuromyotonia and skeletal deformities without prominent Episodic Ataxia.

  Neuromuscular disorders : NMD 20041001

• A spectrophotometric assay of D-glucuronate based on Escherichia coli uronate isomerase and mannonate dehydrogenase.

  Protein expression and purification 20041001

• Testosterone 1 beta-hydroxylation by human cytochrome P450 3A4.

  European journal of biochemistry 20041001

• Prooxidant activity and cytotoxic effects of indole-3-acetic acid derivative radicals.

  Chemical research in toxicology 20041001

• Cloning and enhanced expression of the cytochrome P450nor gene (nicA; CYP55A5) encoding nitric oxide reductase from Aspergillus oryzae.

  Bioscience, biotechnology, and biochemistry 20041001

• Are allopurinol and metabolites found in HPRT deficient erythrocytes responsible for increased NAD synthesis?

  Nucleosides, nucleotides & nucleic acids 20041001

• [Effect of osmoregulation on the plasma membrane redox activity in chilling injury sensitive soybean seeds].

  Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20041001

• Efficiency and mechanisms of the antioxidant effect of standard therapy and refracterin in the treatment of chronic heart failure in elderly patients with postinfarction cardiosclerosis.

  Bulletin of experimental biology and medicine 20041001

• [Protective effect of hydroxysafflor yellow A against rat cortex mitochondrial injuries induced by cerebral ischemia].

  Yao xue xue bao = Acta pharmaceutica Sinica 20041001

• New photoproducts from irradiation of NADH with near-UV light.

  Chemistry & biodiversity 20041001

• The role of active site glutamate residues in catalysis of Rhodobacter capsulatus xanthine dehydrogenase.

  The Journal of biological chemistry 20040924

• Coenzyme specificity of Sir2 protein deacetylases: implications for physiological regulation.

  The Journal of biological chemistry 20040917

• Extracellular NAD+ regulates intracellular free calcium concentration in human monocytes.

  The Biochemical journal 20040915

• Oxidative DNA damage induced by a hydroperoxide derivative of cyclophosphamide.

  Free radical biology & medicine 20040915

• A bioelectrochemical polypyrrole-containing Fe(CN)6(3-) interface for the design of a NAD-dependent reagentless biosensor.

  Biosensors & bioelectronics 20040915

• The earliest events in protein folding: a structural requirement for ultrafast folding in cytochrome C.

  Journal of the American Chemical Society 20040915

• Porphyrin-sensitized nanoparticulate TiO2 as the photoanode of a hybrid photoelectrochemical biofuel cell.

  Langmuir : the ACS journal of surfaces and colloids 20040914

• Generation of reactive oxygen species in the reaction catalyzed by alpha-ketoglutarate dehydrogenase.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908

• Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908

• Importance of Gly-13 for the coenzyme binding of human UDP-glucose dehydrogenase.

  The Journal of biological chemistry 20040903

• Structure of alanine dehydrogenase from Archaeoglobus: active site analysis and relation to bacterial cyclodeaminases and mammalian mu crystallin.

  Journal of molecular biology 20040903

• Structure and action of urocanase.

  Journal of molecular biology 20040903

• Effect of different levels of NADH availability on metabolite distribution in Escherichia coli fermentation in minimal and complex media.

  Applied microbiology and biotechnology 20040901

• Inherent redox properties of diesel exhaust particles: catalysis of the generation of reactive oxygen species by biological reductants.

  Toxicological sciences : an official journal of the Society of Toxicology 20040901

• A comparison between the use of a redox mediator in solution and of surface modified electrodes in the electrocatalytic oxidation of nicotinamide adenine dinucleotide.

  Bioelectrochemistry (Amsterdam, Netherlands) 20040901

• Fluorescence assay of SIRT protein deacetylases using an acetylated peptide substrate and a secondary trypsin reaction.

  Analytical biochemistry 20040901

• Multiple effects of DiS-C3(5) on mitochondrial structure and function.

  European journal of biochemistry 20040901

• A thermostable shikimate 5-dehydrogenase from the archaeon Archaeoglobus fulgidus.

  FEMS microbiology letters 20040901

• Novel catalytic mechanism of glycoside hydrolysis based on the structure of an NAD+/Mn2+ -dependent phospho-alpha-glucosidase from Bacillus subtilis.

  Structure (London, England : 1993) 20040901

• Glyceraldehyde-3-phosphate dehydrogenase is a GABAA receptor kinase linking glycolysis to neuronal inhibition.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040901

• Navigating novel mechanisms of cellular plasticity with the NAD+ precursor and nutrient nicotinamide.

  Frontiers in bioscience : a journal and virtual library 20040901

• Carbon nanotube-chitosan system for electrochemical sensing based on dehydrogenase enzymes.

  Analytical chemistry 20040901

• Metabolism of 4-hydroxy-trans-2-nonenal by central nervous system mitochondria is dependent on age and NAD+ availability.

  Chemical research in toxicology 20040901

• Effect of lead ions on rat erythrocyte purine content.

  Biological trace element research 20040901

• Autofluorescence lifetime imaging of cultivated cells using a UV picosecond laser diode.

  Journal of fluorescence 20040901

• Active-site conformational changes associated with hydride transfer in proton-translocating transhydrogenase.

  Biochemistry 20040831

• Segregation pattern and biochemical effect of the G3460A mtDNA mutation in 27 members of LHON family.

  Journal of the neurological sciences 20040830

• The mitochondrial respiratory chain is partially organized in a supercomplex assembly: kinetic evidence using flux control analysis.

  The Journal of biological chemistry 20040827

• Carbonyl orientation determines regio- and enantioselectivity in 1,2-/1,4-reduction of an NAD model compound.

  Organic letters 20040819

• Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration.

  Science (New York, N.Y.) 20040813

• Impact of protein flexibility on hydride-transfer parameters in thermophilic and psychrophilic alcohol dehydrogenases.

  Journal of the American Chemical Society 20040811

• De novo design, synthesis, and function of semiartificial myoglobin conjugated with coiled-coil two-alpha-helix peptides.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20040806

• Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases.

  Biochemistry 20040803

• Kinetic and structural analysis of the increased affinity of enoyl-ACP (acyl-carrier protein) reductase for triclosan in the presence of NAD+.

  The Biochemical journal 20040801

• Mutational analysis of the triclosan-binding region of enoyl-ACP (acyl-carrier protein) reductase from Plasmodium falciparum.

  The Biochemical journal 20040801

• Investigations on the pharmacology of the cardioprotective guanidine ME10092.

  Journal of cardiovascular pharmacology 20040801

• Metabolism of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine by Clostridium bifermentans strain HAW-1 and several other H2-producing fermentative anaerobic bacteria.

  FEMS microbiology letters 20040801

• Effect of uncouplers on endogenous respiration and ferrous iron oxidation in a chemolithoautotrophic bacterium Acidithiobacillus (Thiobacillus) ferrooxidans.

  FEMS microbiology letters 20040801

• C3 exoenzyme from Clostridium botulinum: structure of a tetragonal crystal form and a reassessment of NAD-induced flexure.

  Acta crystallographica. Section D, Biological crystallography 20040801

• Gender modulation of Ca(2+) uptake in cardiac mitochondria.

  Journal of molecular and cellular cardiology 20040801

• Central role for aldose reductase pathway in myocardial ischemic injury.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040801

• Biochemical characterization of StyAB from Pseudomonas sp. strain VLB120 as a two-component flavin-diffusible monooxygenase.

  Journal of bacteriology 20040801

• NAD+ specificity of bacterial DNA ligase revealed.

  Structure (London, England : 1993) 20040801

• Structural rearrangement accompanying NAD+ synthesis within a bacterial DNA ligase crystal.

  Structure (London, England : 1993) 20040801

• A fluorescence-based technique for screening compounds that protect against damage to brain mitochondria.

  Brain research. Brain research protocols 20040801

• Prevention of myocardial reperfusion injury by poly(ADP-ribose) synthetase inhibitor, 3-aminobenzamide, in cardioplegic solution: in vitro study of isolated rat heart model.

  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20040801

• Thermostable flavin reductase that couples with dibenzothiophene monooxygenase, from thermophilic Bacillus sp. DSM411: purification, characterization, and gene cloning.

  Bioscience, biotechnology, and biochemistry 20040801

• Too much lactate or too little liver?

  Journal of clinical anesthesia 20040801

• Using 31P NMR spectroscopy at 14.1 Tesla to investigate PARP-1 associated energy failure and metabolic rescue in cerebrocortical slices.

  Journal of bioenergetics and biomembranes 20040801

• Energostim in therapy of chronic ischemia of the lower limbs.

  Bulletin of experimental biology and medicine 20040801

• Antioxidant activity of NADH and its analogue--an in vitro study.

  Journal of biochemistry and molecular biology 20040731

• The myenteric plexus of the rat colon after fecal stream diversion: a morpho-quantitative study.

  Autonomic neuroscience : basic & clinical 20040730

• Quantitative NAD(P)H/flavoprotein autofluorescence imaging reveals metabolic mechanisms of pancreatic islet pyruvate response.

  The Journal of biological chemistry 20040723

• Activation by retinoids of the uncoupling protein UCP1.

  Biochimica et biophysica acta 20040723

• Enabling multienzyme biocatalysis using nanoporous materials.

  Biotechnology and bioengineering 20040720

• Protection of tamoxifen against oxidation of mitochondrial thiols and NAD(P)H underlying the permeability transition induced by prooxidants.

  Chemico-biological interactions 20040720

• A hydrogen-evolving enzyme is present in Frankia sp. R43.

  FEMS microbiology letters 20040715

• Sustained glycolytic oscillations--no need for cyanide.

  FEMS microbiology letters 20040715

• Characterization of a thermophilic DNA ligase from the archaeon Thermococcus fumicolans.

  FEMS microbiology letters 20040715

• Modulation of mitochondrial complex I activity by reversible Ca2+ and NADH mediated superoxide anion dependent inhibition.

  Biochemistry 20040706

• A new crystal structure of deoxyhypusine synthase reveals the configuration of the active enzyme and of an enzyme.NAD.inhibitor ternary complex.

  The Journal of biological chemistry 20040702

• Neural activity triggers neuronal oxidative metabolism followed by astrocytic glycolysis.

  Science (New York, N.Y.) 20040702

• Membrane electrochemical reactors (MER) for NADH regeneration in HLADH-catalysed synthesis: comparison of effectiveness.

  Bioprocess and biosystems engineering 20040701

• Beneficial effects of mild lifelong dietary restriction on skeletal muscle: prevention of age-related mitochondrial damage, morphological changes, and vulnerability to a chemical toxin.

  Acta neuropathologica 20040701

• Carbon monoxide improves cardiac energetics and safeguards the heart during reperfusion after cardiopulmonary bypass in pigs.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040701

• Differential effects of norepinephrine on brain and other less vital organs detected by a multisite multiparametric monitoring system.

  Medical science monitor : international medical journal of experimental and clinical research 20040701

• D88A mutant of cytochrome P450nor provides kinetic evidence for direct complex formation with electron donor NADH.

  European journal of biochemistry 20040701

• The NAD+ precursor nicotinamide governs neuronal survival during oxidative stress through protein kinase B coupled to FOXO3a and mitochondrial membrane potential.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20040701

• A multisubunit membrane-bound [NiFe] hydrogenase and an NADH-dependent Fe-only hydrogenase in the fermenting bacterium Thermoanaerobacter tengcongensis.

  Microbiology (Reading, England) 20040701

• Efficiency of refracterin in patients with chronic cardiac insufficiency caused by coronary heart disease.

  Bulletin of experimental biology and medicine 20040701

• Effect of angiotensin II on energetics, glucose metabolism and cytosolic NADH/NAD and NADPH/NADP redox in vascular smooth muscle.

  Molecular and cellular biochemistry 20040701

• Dihydrolipoamide dehydrogenase from porcine heart catalyzes NADH-dependent scavenging of nitric oxide.

  FEBS letters 20040618

• Dual functional roles of ATP in the human mitochondrial malic enzyme.

  Biochemistry 20040615

• Characterization of Mycobacterium tuberculosis NAD kinase: functional analysis of the full-length enzyme by site-directed mutagenesis.

  Biochemistry 20040615

• Absence of NADH channeling in coupled reaction of mitochondrial malate dehydrogenase and complex I in alamethicin-permeabilized rat liver mitochondria.

  Biochemical and biophysical research communications 20040611

• Cell surface oxygen consumption by mitochondrial gene knockout cells.

  Biochimica et biophysica acta 20040607

• Limited transfer of cytosolic NADH into mitochondria at high cardiac workload.

  American journal of physiology. Heart and circulatory physiology 20040601

• Langmuir-Blodgett films incorporating redox mediators for molecular recognition of NADH.

  Bioelectrochemistry (Amsterdam, Netherlands) 20040601

• Model evaluation for glycolytic oscillations in yeast biotransformations of xenobiotics.

  Biophysical chemistry 20040601

• Oxidation of pyocyanin, a cytotoxic product from Pseudomonas aeruginosa, by microperoxidase 11 and hydrogen peroxide.

  Free radical biology & medicine 20040601

• Synthesis, molecular modeling, and evaluation of nonphenolic indole analogs of mycophenolic acid.

  Bioorganic & medicinal chemistry 20040601

• Alkylating DNA damage stimulates a regulated form of necrotic cell death.

  Genes & development 20040601

• Acute ammonia intoxication induces an NMDA receptor-mediated increase in poly(ADP-ribose) polymerase level and NAD metabolism in nuclei of rat brain cells.

  Journal of neurochemistry 20040601

• Performance characteristics of a recombinant enzymatic cycling assay for quantification of total homocysteine in serum or plasma.

  Clinica chimica acta; international journal of clinical chemistry 20040601

• The ternary complex of Pseudomonas aeruginosa alcohol dehydrogenase with NADH and ethylene glycol.

  Protein science : a publication of the Protein Society 20040601

• Thermodynamic basis of electron transfer in dihydroorotate dehydrogenase B from Lactococcus lactis: analysis by potentiometry, EPR spectroscopy, and ENDOR spectroscopy.

  Biochemistry 20040601

• Race-specific differences in endothelial function: predisposition of African Americans to vascular diseases.

  Circulation 20040601

• Chemical reversibility and stable low-potential NADH detection with nonconventional conducting polymer nanotubule modified glassy carbon electrodes.

  Analytical chemistry 20040601

• Disturbed trafficking of dystrophin and associated proteins in targetoid phenomena after chronic muscle denervation.

  Neuropathology and applied neurobiology 20040601

• Muscle dysfunction during exercise of a single skeletal muscle in rats with congestive heart failure is not associated with reduced muscle blood supply.

  Acta physiologica Scandinavica 20040601

• Transient species in the stepwise interconversion of NADH and NAD+.

  Accounts of chemical research 20040601

• Extracellular 3beta-hydroxysteroid oxidase of Mycobacterium vaccae VKM Ac-1815D.

  The Journal of steroid biochemistry and molecular biology 20040601

• A two-dimensional imaging biosensor to monitor enhanced brain glutamate release stimulated by nicotine.

  Journal of neuroscience methods 20040530

• Significance of the epsilon subunit in the thiol modulation of chloroplast ATP synthase.

  Biochemical and biophysical research communications 20040521

• Direct desaturation of free myristic acid by hen liver microsomal Delta9-desaturase without prior activation to myristoyl-CoA derivative.

  Journal of agricultural and food chemistry 20040519

• Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function.

  The Biochemical journal 20040515

• Oxidation and reduction of pyridine nucleotides in alamethicin-permeabilized plant mitochondria.

  The Biochemical journal 20040515

• Comparative study of electron mediators used in the electrochemical oxidation of NADH.

  Biosensors & bioelectronics 20040515

• Development of urease and glutamic dehydrogenase amperometric assay for heavy metals screening in polluted samples.

  Biosensors & bioelectronics 20040515

• Human mitochondrial thioredoxin reductase reduces cytochrome c and confers resistance to complex III inhibition.

  Free radical biology & medicine 20040515

• Effect of coenzyme Q10 on the mitochondrial function of skin fibroblasts from Parkinson patients.

  Journal of the neurological sciences 20040515

• NADH oxidation by the Na+-translocating NADH:quinone oxidoreductase from Vibrio cholerae: functional role of the NqrF subunit.

  The Journal of biological chemistry 20040514

• Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans.

  Cell 20040514

• Inhibitors of ADP-ribosylating bacterial toxins based on oxacarbenium ion character at their transition states.

  Journal of the American Chemical Society 20040512

• Crystal structure and amide H/D exchange of binary complexes of alcohol dehydrogenase from Bacillus stearothermophilus: insight into thermostability and cofactor binding.

  Biochemistry 20040511

• Studies of the enzymic mechanism of Candida tenuis xylose reductase (AKR 2B5): X-ray structure and catalytic reaction profile for the H113A mutant.

  Biochemistry 20040504

• Excited-state behavior and photoionization of 1,8-acridinedione dyes in micelles--comparison with NADH oxidation.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20040503

• NADH-dependent metabolism of nitric oxide in alfalfa root cultures expressing barley hemoglobin.

  Planta 20040501

• Molecular biology of pyridine nucleotide and nicotine biosynthesis.

  Frontiers in bioscience : a journal and virtual library 20040501

• Morphology-associated expression of NADP-dependent glutamate dehydrogenases during yeast-mycelium transition of a dimorphic fungus Benjaminiella poitrasii.

  Antonie van Leeuwenhoek 20040501

• Poly(ADP-ribose) polymerase and renal hypothermic preservation injury.

  American journal of physiology. Renal physiology 20040501

• Homology modeling and molecular dynamics studies of a novel C3-like ADP-ribosyltransferase.

  Bioorganic & medicinal chemistry 20040501

• Transient-phase kinetic studies on the nucleotide binding to 3alpha-hydroxysteroid dehydrogenase from Pseudomonas sp. B-0831 using fluorescence stopped-flow procedures.

  European journal of biochemistry 20040501

• A novel mutation in the caveolin-3 gene causing familial isolated hyperCKaemia.

  Neuromuscular disorders : NMD 20040501

• Protection by pyruvate of rat retinal cells against zinc toxicity in vitro, and pressure-induced ischemia in vivo.

  Investigative ophthalmology & visual science 20040501

• A general method for the analysis of random bisubstrate enzyme mechanisms.

  Journal of industrial microbiology & biotechnology 20040501

• Cerebrospinal fluid analysis differentiates multiple system atrophy from Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20040501

• Fourier transform infrared spectroscopic study on the conformational reorganization in Escherichia coli complex I due to redox-driven proton translocation.

  Biopolymers 20040501

• Involvement of a Glu71-Arg64 couple in the access channel for NADH in cytochrome p450nor.

  Bioscience, biotechnology, and biochemistry 20040501

• Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition.

  The Journal of biological chemistry 20040430

• Inactivation of mitochondrial electron transport by photosensitization of a pheophorbide a derivative.

  Molecules and cells 20040430

• Reduction of an aldehyde by a NADH/Zn2+ -dependent redox active ribozyme.

  Journal of the American Chemical Society 20040428

• Opening of the mitochondrial permeability transition pore induces reactive oxygen species production at the level of the respiratory chain complex I.

  The Journal of biological chemistry 20040423

• Quinone analogues regulate mitochondrial substrate competitive oxidation.

  Biochemical and biophysical research communications 20040416

• A novel NADH-linked l-xylulose reductase in the l-arabinose catabolic pathway of yeast.

  The Journal of biological chemistry 20040409

• Human erythrocyte recycling of ascorbic acid: relative contributions from the ascorbate free radical and dehydroascorbic acid.

  The Journal of biological chemistry 20040409

• Photosensitized NADH formation system with multilayer TiO2 film.

  Chemical communications (Cambridge, England) 20040407

• The structure of the 1L-myo-inositol-1-phosphate synthase-NAD+-2-deoxy-D-glucitol 6-(E)-vinylhomophosphonate complex demands a revision of the enzyme mechanism.

  The Journal of biological chemistry 20040402

• Glutamate-induced differential mitochondrial response in young and adult rats.

  Neurochemistry international 20040401

• Preservation of complex I function during hypoxia-reoxygenation-induced mitochondrial injury in proximal tubules.

  American journal of physiology. Renal physiology 20040401

• Resistance to disuse atrophy in a turtle hindlimb muscle.

  Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20040401

• Impaired 11-beta hydroxysteroid dehydrogenase type 2 activity in sweat gland ducts in human essential hypertension.

  Hypertension (Dallas, Tex. : 1979) 20040401

• Molecular cloning, overexpression, purification, and characterization of an aerobic FMN-dependent azoreductase from Enterococcus faecalis.

  Protein expression and purification 20040401

• Multiple formaldehyde oxidation/detoxification pathways in Burkholderia fungorum LB400.

  Journal of bacteriology 20040401

• p22phox-derived superoxide mediates enhanced proliferative capacity of diabetic vascular smooth muscle cells.

  Diabetes research and clinical practice 20040401

• Separation of fluorescence signals from Ca2+ and NADH during cardioplegic arrest and cardiac ischemia.

  Cell calcium 20040401

• Crystallization and preliminary crystallographic analysis of the NAD(H)-binding domain of Escherichia coli transhydrogenase.

  Acta crystallographica. Section D, Biological crystallography 20040401

• Electropolymerized flavin adenine dinucleotide as an advanced NADH transducer.

  Analytical chemistry 20040401

• Effect of pyruvate kinase overproduction on glucose metabolism of Lactococcus lactis.

  Microbiology (Reading, England) 20040401

• Biochemistry, biology, and pharmacology of cyclic adenosine diphosphoribose (cADPR).

  Current medicinal chemistry 20040401

• Ecto-ADP-ribosyltransferases (ARTs): emerging actors in cell communication and signaling.

  Current medicinal chemistry 20040401

• Structure and function of nicotinamide mononucleotide adenylyltransferase.

  Current medicinal chemistry 20040401

• Cofactor mimics as selective inhibitors of NAD-dependent inosine monophosphate dehydrogenase (IMPDH)--the major therapeutic target.

  Current medicinal chemistry 20040401

• Inhibition of chlorophyll biosynthesis by mercury in excised etiolated maize leaf segments during greening: effect of 2-oxoglutarate.

  Indian journal of experimental biology 20040401

• Enzymatic properties of pierisin-1 and its N-terminal domain, a guanine-specific ADP-ribosyltransferase from the cabbage butterfly.

  Journal of biochemistry 20040401

• Involvement of NADPH oxidase in hydrogen peroxide accumulation by Aspergillus niger elicitor-induced Taxus chinensis cell cultures.

  Journal of plant physiology 20040401

• Hepatoprotective effect of Sabina przewalskii against menadione-induced toxicity.

  Phytotherapy research : PTR 20040401

• Evaluation of orally active poly(ADP-ribose) polymerase inhibitor in streptozotocin-diabetic rat model of early peripheral neuropathy.

  Diabetologia 20040401

• Modulation of [Ca2+]i signaling dynamics and metabolism by perinuclear mitochondria in mouse parotid acinar cells.

  The Journal of biological chemistry 20040326

• Structural studies on flavin reductase PheA2 reveal binding of NAD in an unusual folded conformation and support novel mechanism of action.

  The Journal of biological chemistry 20040326

• A novel NAD-binding protein revealed by the crystal structure of 2,3-diketo-L-gulonate reductase (YiaK).

  The Journal of biological chemistry 20040326

• Methanoarchaeal sulfolactate dehydrogenase: prototype of a new family of NADH-dependent enzymes.

  The EMBO journal 20040324

• Participation of histidine-51 in catalysis by horse liver alcohol dehydrogenase.

  Biochemistry 20040323

• Crystal structure at 1.8 A resolution of CDP-D-glucose 4,6-dehydratase from Yersinia pseudotuberculosis.

  Biochemistry 20040323

• Effects of cytosolic NADH/NAD(+) levels on sarcoplasmic reticulum Ca(2+) release in permeabilized rat ventricular myocytes.

  The Journal of physiology 20040316

• Tracking variations in nicotinamide cofactors extracted from cultured cells using capillary electrophoresis with multiphoton excitation of fluorescence.

  Analytical biochemistry 20040315

• The importance of redox regulated pathways in sperm cell biology.

  Molecular and cellular endocrinology 20040315

• Structural basis for the mechanism and regulation of Sir2 enzymes.

  Molecular cell 20040312

• Hydricities of BzNADH, CH5Mo(PMe3)(CO)2H, and C5Me5Mo(PMe3)(CO)2H in acetonitrile.

  Journal of the American Chemical Society 20040310

• Genistein and daidzein induce cell proliferation and their metabolites cause oxidative DNA damage in relation to isoflavone-induced cancer of estrogen-sensitive organs.

  Biochemistry 20040309

• NADH oxidase activity of rat cardiac sarcoplasmic reticulum regulates calcium-induced calcium release.

  Circulation research 20040305

• NADH, a new player in the cardiac ryanodine receptor?

  Circulation research 20040305

• An enzymatic assay for poly(ADP-ribose) polymerase-1 (PARP-1) via the chemical quantitation of NAD(+): application to the high-throughput screening of small molecules as potential inhibitors.

  Analytical biochemistry 20040301

• Nicotinamide suppresses hyperphosphatemia in hemodialysis patients.

  Kidney international 20040301

• Cytoprotective effect of gallotannin in oxidatively stressed HaCaT keratinocytes: the role of poly(ADP-ribose) metabolism.

  Experimental dermatology 20040301

• The new life of a centenarian: signalling functions of NAD(P).

  Trends in biochemical sciences 20040301

• Progressive sensorimotor impairment is not associated with reduced dopamine and high energy phosphate donors in a model of ataxia-telangiectasia.

  Journal of neurochemistry 20040301

• Reliable, sensitive, rapid and quantitative enzyme-based assay for gamma-hydroxybutyric acid (GHB).

  Journal of forensic sciences 20040301

• Heterogenic response of the liver parenchyma to ethanol studied in the bivascularly perfused rat liver.

  Molecular and cellular biochemistry 20040301

• A novel NADH-dependent carbonyl reductase from Kluyveromyces aestuarii and comparison of NADH-regeneration system for the synthesis of ethyl (S)-4-chloro-3-hydroxybutanoate.

  Bioscience, biotechnology, and biochemistry 20040301

• Mechanism of protective effect of energostim during catalepsy produced by single treatment with trifluoperazine.

  Bulletin of experimental biology and medicine 20040301

• Characterization of recombinant Drosophila melanogaster myo-inositol-1-phosphate synthase expressed in Escherichia coli.

  Journal of microbiology (Seoul, Korea) 20040301

• Scientific community. Aging research's family feud.

  Science (New York, N.Y.) 20040227

• The effect of cytoplasmic Ca2+ signal on the redox state of mitochondrial pyridine nucleotides.

  Molecular and cellular endocrinology 20040227

• Crystal structure of putidaredoxin reductase from Pseudomonas putida, the final structural component of the cytochrome P450cam monooxygenase.

  Journal of molecular biology 20040227

• The soluble and membrane-bound transhydrogenases UdhA and PntAB have divergent functions in NADPH metabolism of Escherichia coli.

  The Journal of biological chemistry 20040220

• A monooxygenase catalyzes sequential dechlorinations of 2,4,6-trichlorophenol by oxidative and hydrolytic reactions.

  The Journal of biological chemistry 20040220

• Kinetic mechanism and quaternary structure of Aminobacter aminovorans NADH:flavin oxidoreductase: an unusual flavin reductase with bound flavin.

  Biochemistry 20040217

• Metal-Induced reversible structural interconversion of human mitochondrial NAD(P)+-dependent malic enzyme.

  Proteins 20040215

• An inorganic iron complex that inhibits wild-type and an isoniazid-resistant mutant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis.

  Chemical communications (Cambridge, England) 20040207

• Structure of Toxoplasma gondii LDH1: active-site differences from human lactate dehydrogenases and the structural basis for efficient APAD+ use.

  Biochemistry 20040203

• NADH-reductive stress in Saccharomyces cerevisiae induces the expression of the minor isoform of glyceraldehyde-3-phosphate dehydrogenase (TDH1).

  Current genetics 20040201

• Synthesis and utility of 14C-labeled nicotinamide cofactors.

  Analytical biochemistry 20040201

• Structural alteration of cofactor specificity in Corynebacterium 2,5-diketo-D-gluconic acid reductase.

  Protein science : a publication of the Protein Society 20040201

• Anthocyanidin reductases from Medicago truncatula and Arabidopsis thaliana.

  Archives of biochemistry and biophysics 20040201

• Chemotaxis and calcium responses of phagocytes to formyl peptide receptor ligands is differentially regulated by cyclic ADP ribose.

  Journal of immunology (Baltimore, Md. : 1950) 20040201

• Graded reoxygenation with chemical inhibition of oxidative phosphorylation improves posthypoxic recovery in murine hippocampal slices.

  Journal of neuroscience research 20040201

• Antidepressant-like effect of nicotinamide adenine dinucleotide in the forced swim test in rats.

  Pharmacology, biochemistry, and behavior 20040201

• Glycogen metabolism in the rat retina.

  Journal of neurochemistry 20040201

• Selective release and function of one of the two FMN groups in the cytoplasmic NAD+-reducing [NiFe]-hydrogenase from Ralstonia eutropha.

  European journal of biochemistry 20040201

• Novel poly(ADP-ribose) polymerase-1 inhibitor, AG14361, restores sensitivity to temozolomide in mismatch repair-deficient cells.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040201

• Structure of a cDNA for Ciona Cytochrome b(5) and the ubiquitous expression of mRNA in embryonic tissues.

  Journal of biochemistry 20040201

• Neuroprotective effect of 4-amino-1,8-napthalimide, a poly(ADP ribose) polymerase inhibitor in middle cerebral artery occlusion-induced focal cerebral ischemia in rat.

  Brain research bulletin 20040201

• Inhibition of the bacterial enoyl reductase FabI by triclosan: a structure-reactivity analysis of FabI inhibition by triclosan analogues.

  Journal of medicinal chemistry 20040129

• Inhibitory effect of natural phenolic lipids upon NAD-dependent dehydrogenases and on triglyceride accumulation in 3T3-L1 cells in culture.

  Journal of agricultural and food chemistry 20040128

• The action of extracellular NAD+ on Ca2+ efflux, hemodynamics and some metabolic parameters in the isolated perfused rat liver.

  European journal of pharmacology 20040126

• The PARP inhibitor benzamide protects against kainate and NMDA but not AMPA lesioning of the mouse striatum in vivo.

  Brain research 20040116

• Aplysia californica mediated cyclisation of novel 3'-modified NAD+ analogues: a role for hydrogen bonding in the recognition of cyclic adenosine 5'-diphosphate ribose.

  Bioorganic & medicinal chemistry 20040115

• Toward the elucidation of the catalytic mechanism of the mono-ADP-ribosyltransferase activity of Pseudomonas aeruginosa exotoxin A.

  Biochemistry 20040113

• Genes malh and pagl of Clostridium acetobutylicum ATCC 824 encode NAD+- and Mn2+-dependent phospho-alpha-glucosidase(s).

  The Journal of biological chemistry 20040109

• The 2.9A resolution crystal structure of malate dehydrogenase from Archaeoglobus fulgidus: mechanisms of oligomerisation and thermal stabilisation.

  Journal of molecular biology 20040102

• High-resolution visualization of oxygen distribution in the liver in vivo.

  American journal of physiology. Gastrointestinal and liver physiology 20040101

• Myocardial contractile function during postischemic low-flow reperfusion: critical thresholds of NADH and O2 delivery.

  American journal of physiology. Heart and circulatory physiology 20040101

• Biophysical properties and metabolic regulation of a TASK-like potassium channel in rat carotid body type 1 cells.

  American journal of physiology. Lung cellular and molecular physiology 20040101

• Functional characterization of an alternative [lactate dehydrogenase-like] malate dehydrogenase in Plasmodium falciparum.

  Parasitology research 20040101

• Enzymology of NAD+ homeostasis in man.

  Cellular and molecular life sciences : CMLS 20040101

• In vitro metabolism of hyperforin in rat liver microsomal systems.

  Drug metabolism and disposition: the biological fate of chemicals 20040101

• Novel pathway for utilization of cyclopropanecarboxylate by Rhodococcus rhodochrous.

  Applied and environmental microbiology 20040101

• Calorie restriction extends yeast life span by lowering the level of NADH.

  Genes & development 20040101

• Effects of excess nicotinamide administration on the urinary excretion of nicotinamide N-oxide and nicotinuric acid by rats.

  Bioscience, biotechnology, and biochemistry 20040101

• Organization and regulation of the cytosolic NADH metabolism in the yeast Saccharomyces cerevisiae.

  Molecular and cellular biochemistry 20040101

• Construction of an electro-enzymatic bioreactor for the production of (R)-mandelate from benzoylformate.

  Biotechnology letters 20040101

• Regulatory role of lactate in wound repair.

  Methods in enzymology 20040101

• Is aldosterone bad for the heart?

  Trends in endocrinology and metabolism: TEM 20040101

• Regulation of NADH/CoQ oxidoreductase: do phosphorylation events affect activity?

  The protein journal 20040101

• Differential metabolic effects on mitochondria by silica hydride using capillary electrophoresis.

  Journal of medicinal food 20040101

• Mitochondrial NADH redox state, monitoring discovery and deployment in tissue.

  Methods in enzymology 20040101

• Treatment of Alzheimer's disease with stabilized oral nicotinamide adenine dinucleotide: a randomized, double-blind study.

  Drugs under experimental and clinical research 20040101

• Antimycin A treatment decreases respiratory internal rotenone-insensitive NADH oxidation capacity in potato leaves.

  BMC plant biology 20040101

• Effect of preculturing conditions on growth of Lactobacillus rhamnosus on medium containing glucose and citrate.

  Microbiological research 20040101

• Cytosolic NADP phosphatases I and II from Arthrobacter sp. strain KM: implication in regulation of NAD+/NADP+ balance.

  Journal of basic microbiology 20040101

• Computational studies of the effects of myocardial blood flow reductions on cardiac metabolism.

  Biomedical engineering online 20040101

• [Cardioprotective effect of energostim in toxic allergic myocarditis].

  Eksperimental'naia i klinicheskaia farmakologiia 20040101

• Molecular adaptation: the malate dehydrogenase from the extreme halophilic bacterium Salinibacter ruber behaves like a non-halophilic protein.

  Biochimie 20040101

• [Activity of the key enzymes in xylose-assimilating yeasts at different rates of oxygen transfer to the fermentation medium].

  Mikrobiologiia 20040101

• Poly(ADP-ribosyl)ation enhancement in brain cell nuclei is associated with diabetic neuropathy.

  Journal of diabetes and its complications 20040101

• Redox ratio of mitochondria as an indicator for the response of photodynamic therapy.

  Journal of biomedical optics 20040101

• Circadian tracking of nicotinamide cofactor levels in an immortalized suprachiasmatic nucleus cell line.

  Neuroscience 20040101

• Integrated analysis of metabolic phenotypes in Saccharomyces cerevisiae.

  BMC genomics 20040101

• Repression of reserve lipid turnover in Cunninghamella echinulata and Mortierella isabellina cultivated in multiple-limited media.

  Journal of applied microbiology 20040101

• Metabolic analysis of Corynebacterium glutamicum during lactate and succinate productions under oxygen deprivation conditions.

  Journal of molecular microbiology and biotechnology 20040101

• [Rotenone-insensitive NADH oxydation in mitochondrial suspension occurs by NADH dehydrogenase of respiratory chain fragments].

  Biofizika 20040101

• The effects of organic solvents on poly(ADP-ribose) polymerase-1 activity: implications for neurotoxicity.

  Acta neurobiologiae experimentalis 20040101

• Fluorescence measurements of steady state peroxynitrite production upon SIN-1 decomposition: NADH versus dihydrodichlorofluorescein and dihydrorhodamine 123.

  Journal of fluorescence 20040101

• Constructing biological pathway models with hybrid functional Petri nets.

  In silico biology 20040101

• [Effect of intermittent hypoxic training on indices of adaptation to hypoxia in rats during physical exertion].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20040101

• How tyrosine phosphorylation affects the UDP-glucose dehydrogenase activity of Bacillus subtilis YwqF.

  Journal of molecular microbiology and biotechnology 20040101

• [Redox-state of NAD pairs and activity of lactatedehydrogenase and NADase in guinea pig tissues at different stages of development of experimental allergic encephalomyelitis].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20040101

• Mechanism of nicotinamide inhibition and transglycosidation by Sir2 histone/protein deacetylases.

  The Journal of biological chemistry 20031219

• Yeast life-span extension by calorie restriction is independent of NAD fluctuation.

  Science (New York, N.Y.) 20031219

• First estimation of C4-H bond dissociation energies of NADH and its radical cation in aqueous solution.

  Journal of the American Chemical Society 20031217

• Crystal structure of a ternary complex of the alcohol dehydrogenase from Sulfolobus solfataricus.

  Biochemistry 20031216

• Au nanoparticle-enhanced surface plasmon resonance sensing of biocatalytic transformations.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20031215

• Cofactor binding modulates the conformational stabilities and unfolding patterns of NAD(+)-dependent DNA ligases from Escherichia coli and Thermus scotoductus.

  The Journal of biological chemistry 20031212

• Targeting enzymes involved in spermidine metabolism of parasitic protozoa--a possible new strategy for anti-parasitic treatment.

  Parasitology research 20031201

• Significance of phosphoglucose isomerase for the shift between heterolactic and mannitol fermentation of fructose by Oenococcus oeni.

  Archives of microbiology 20031201

• Adenosine binding sites at S-adenosylhomocysteine hydrolase are controlled by the NAD+/NADH ratio of the enzyme.

  Biochemical pharmacology 20031201

• Purification and properties of the formate dehydrogenase and characterization of the fdhA gene of Sulfurospirillum multivorans.

  Archives of microbiology 20031201

• Monitoring enzymatic reactions in nanolitre wells.

  Journal of microscopy 20031201

• Rational proteomics I. Fingerprint identification and cofactor specificity in the short-chain oxidoreductase (SCOR) enzyme family.

  Proteins 20031201

• Structural genomics of Caenorhabditis elegans: structure of dihydropteridine reductase.

  Proteins 20031201

• Structure of rabbit-muscle glyceraldehyde-3-phosphate dehydrogenase.

  Acta crystallographica. Section D, Biological crystallography 20031201

• The existence of an NAD-dependent pathway for retinoic acid formation from vitamin A (retinol) in rat esophagus and its inhibition by ethanol and histamine 2 (H2) receptor antagonists.

  Medical science monitor : international medical journal of experimental and clinical research 20031201

• Cytosol-mitochondria transfer of reducing equivalents by a lactate shuttle in heterotrophic Euglena.

  European journal of biochemistry 20031201

• Superoxide does not mediate the acute vasoconstrictor effects of angiotensin II: a study in human and porcine arteries.

  Journal of hypertension 20031201

• Isolated durum wheat and potato cell mitochondria oxidize externally added NADH mostly via the malate/oxaloacetate shuttle with a rate that depends on the carrier-mediated transport.

  Plant physiology 20031201

• Proteomic analysis of Candida magnoliae strains by two-dimensional gel electrophoresis and mass spectrometry.

  Proteomics 20031201

• How to find 'missing' genes.

  Chemistry & biology 20031201

• NAD biosynthesis: identification of the tryptophan to quinolinate pathway in bacteria.

  Chemistry & biology 20031201

• Effects of iron limitation on the respiratory chain and the membrane cytochrome pattern of the Euryarchaeon Halobacterium salinarum.

  Biological chemistry 20031201

• Substrate specificity of glutaminyl cyclases from plants and animals.

  Biological chemistry 20031201

• Coenzyme specificity of enzymes in the oxidative pentose phosphate pathway of Gluconobacter oxydans.

  Bioscience, biotechnology, and biochemistry 20031201

• Cloning and characterization of the NAD-dependent 7alpha-Hydroxysteroid dehydrogenase from Bacteroides fragilis.

  Current microbiology 20031201

• Triggering of T-cell apoptosis by toxin-related ecto-ADP-ribosyltransferase ART2.

  Annals of the New York Academy of Sciences 20031201

• Purification and partial characterisation of camel milk xanthine oxidoreductase.

  Archives of physiology and biochemistry 20031201

• Preparation of poly(thionine) modified screen-printed carbon electrode and its application to determine NADH in flow injection analysis system.

  Biosensors & bioelectronics 20031130

• Phenol hydroxylase from Bacillus thermoglucosidasius A7, a two-protein component monooxygenase with a dual role for FAD.

  The Journal of biological chemistry 20031128

• Tryptophan phosphorescence spectroscopy reveals that a domain in the NAD(H)-binding component (dI) of transhydrogenase from Rhodospirillum rubrum has an extremely rigid and conformationally homogeneous protein core.

  The Journal of biological chemistry 20031128

• The structure of the S127P mutant of cytochrome b5 reductase that causes methemoglobinemia shows the AMP moiety of the flavin occupying the substrate binding site.

  Biochemistry 20031118

• Critical residues for the coenzyme specificity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase.

  Archives of biochemistry and biophysics 20031115

• The crystal structure of C3stau2 from Staphylococcus aureus and its complex with NAD.

  The Journal of biological chemistry 20031114

• H-tunneling in the multiple H-transfers of the catalytic cycle of morphinone reductase and in the reductive half-reaction of the homologous pentaerythritol tetranitrate reductase.

  The Journal of biological chemistry 20031107

• Fluorometric studies of ligand-induced conformational changes of CD38.

  Biochimica et biophysica acta 20031103

• Regulation of oxidative phosphorylation in different muscles and various experimental conditions.

  The Biochemical journal 20031101

• Nicotinamide offers multiple protective mechanisms in stroke as a precursor for NAD+, as a PARP inhibitor and by partial restoration of mitochondrial function.

  Pharmacology 20031101

• Perflubron emulsion improves hepatic microvascular integrity and mitochondrial redox state after hemorrhagic shock.

  Shock (Augusta, Ga.) 20031101

• Sepsis-induced failure of hepatic energy metabolism.

  The Journal of surgical research 20031101

• FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.

  Cancer research 20031101

• Oxidative DNA damage induced by benz[a]anthracene metabolites via redox cycles of quinone and unique non-quinone.

  Chemical research in toxicology 20031101

• NarE: a novel ADP-ribosyltransferase from Neisseria meningitidis.

  Molecular microbiology 20031101

• Carbohydrate metabolism in erythrocytes of copper deficient rats.

  The Journal of nutritional biochemistry 20031101

• Application of polyaniline/sol-gel derived tetraethylorthosilicate films to an amperometric lactate biosensor.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20031101

• 1-Methyl-3-nitropyridine: an efficient oxidant of NADH in non-enzymatic and enzyme-mediated processes.

  Free radical research 20031101

• Single-sample preparation for simultaneous cellular redox and energy state determination.

  Analytical biochemistry 20031101

• Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2-mediated transcriptional repression.

  The Journal of biological chemistry 20031031

• Active oxygen species generated from photoexcited fullerene (C60) as potential medicines: O2-* versus 1O2.

  Journal of the American Chemical Society 20031022

• Poly ADP-ribose polymerase (PARP) inhibitors transiently protect leukemia cells from alkylating agent induced cell death by three different effects.

  European journal of medical research 20031022

• Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated proliferation of human peripheral blood mononuclear cells.

  The Biochemical journal 20031015

• Superoxide and hydrogen peroxide production by Drosophila mitochondria.

  Free radical biology & medicine 20031015

• Metabolic network control of oxidative phosphorylation: multiple roles of inorganic phosphate.

  The Journal of biological chemistry 20031003

• An efficient and selective enzymatic oxidation system for the synthesis of enantiomerically pure D-tert-leucine.

  Organic letters 20031002

• Structure and autoregulation of the yeast Hst2 homolog of Sir2.

  Nature structural biology 20031001

• The structure of NADH in the enzyme dTDP-d-glucose dehydratase (RmlB).

  Journal of the American Chemical Society 20031001

• Structure and mechanism of a bacterial haloalcohol dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site.

  The EMBO journal 20031001

• NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor.

  Immunity 20031001

• Bioelectrocatalysts: engineered oxidoreductase system for utilization of fumarate reductase in chemical synthesis, detection, and fuel cells.

  Applied biochemistry and biotechnology 20031001

• Enzyme-assisted suicide: molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase.

  Chemistry & biology 20031001

• Purification and characterization of an alpha-haloketone-resistant formate dehydrogenase from Thiobacillus sp. strain KNK65MA, and cloning of the gene.

  Bioscience, biotechnology, and biochemistry 20031001

• Trypanosoma cruzi: molecular cloning and characterization of the S-adenosylhomocysteine hydrolase.

  Experimental parasitology 20031001

• NMR studies of the interaction of a type II dihydrofolate reductase with pyridine nucleotides reveal unexpected phosphatase and reductase activity.

  Biochemistry 20030930

• Escherichia coli cystathionine gamma-synthase does not obey ping-pong kinetics. Novel continuous assays for the elimination and substitution reactions.

  Biochemistry 20030930

• Crystallographic studies on Ascaris suum NAD-malic enzyme bound to reduced cofactor and identification of an effector site.

  The Journal of biological chemistry 20030926

• Purification, characterization, and physiological response of a catalase-peroxidase in Mycobacterium sp. strain JC1 DSM 3803 grown on methanol.

  FEMS microbiology letters 20030926

• Functional split and crosslinking of the membrane domain of the beta subunit of proton-translocating transhydrogenase from Escherichia coli.

  Biochemistry 20030923

• Production of reactive oxygen species by mitochondria: central role of complex III.

  The Journal of biological chemistry 20030919

• Formamides mimic aldehydes and inhibit liver alcohol dehydrogenases and ethanol metabolism.

  The Journal of biological chemistry 20030919

• The three-dimensional structures of the Mycobacterium tuberculosis dihydrodipicolinate reductase-NADH-2,6-PDC and -NADPH-2,6-PDC complexes. Structural and mutagenic analysis of relaxed nucleotide specificity.

  Biochemistry 20030916

• Inhibition of indoleamine 2,3-dioxygenase activity in IFN-gamma stimulated astroglioma cells decreases intracellular NAD levels.

  Biochemical pharmacology 20030915

• A novel sensor of NADH/NAD+ redox poise in Streptomyces coelicolor A3(2).

  The EMBO journal 20030915

• D-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease.

  The Journal of clinical investigation 20030915

• Probing the roles of key residues in the unique regulatory NADH binding site of type II citrate synthase of Escherichia coli.

  The Journal of biological chemistry 20030912

• Structure/function relationships responsible for coenzyme specificity and the isomerase activity of human type 1 3 beta-hydroxysteroid dehydrogenase/isomerase.

  The Journal of biological chemistry 20030912

• Occurrence of two different glutamate dehydrogenase activities in the halophilic bacterium Salinibacter ruber.

  FEMS microbiology letters 20030912

• Ageing: a toast to long life.

  Nature 20030911

• Hormonal control of ADP-ribosyl cyclase activity in pancreatic acinar cells from rats.

  The Journal of biological chemistry 20030905

• Mutational, structural, and kinetic studies of the ATP-binding site of Methanobacterium thermoautotrophicum nicotinamide mononucleotide adenylyltransferase.

  The Journal of biological chemistry 20030905

• NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes.

  Biochemical and biophysical research communications 20030905

• Substrate binding and catalysis of ecto-ADP-ribosyltransferase 2.2 from rat.

  Biochemistry 20030902

• Enzymatic assays for NAD-dependent deacetylase activities.

  Methods (San Diego, Calif.) 20030901

• Pyruvate inhibits zinc-mediated pancreatic islet cell death and diabetes.

  Diabetologia 20030901

• Characterization of the Tuber borchii nitrate reductase gene and its role in ectomycorrhizae.

  Molecular genetics and genomics : MGG 20030901

• An alcohol dehydrogenase ribozyme.

  Nature structural biology 20030901

• Identification of the C-signal, a contact-dependent morphogen coordinating multiple developmental responses in Myxococcus xanthus.

  Genes & development 20030901

• 5'-(2-Nitrophenylalkanoyl)-2'-deoxy-5-fluorouridines as potential prodrugs of FUDR for reductive activation.

  Bioorganic & medicinal chemistry 20030901

• Multi-NMR and fluorescence spectra study the effects of aluminum(III) on coenzyme NADH in aqueous solutions.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030901

• Enzymatic and oxidative metabolites of lycopene.

  The Journal of nutritional biochemistry 20030901

• Chemical modification of catalytically essential functional groups of NAD-dependent hydrogenase from Ralstonia eutropha H16.

  Biochemistry. Biokhimiia 20030901

• Effect of richlocaine alone or in combination with energostim on the severity of endotoxemia and survival of the skin under conditions of reduced blood flow.

  Bulletin of experimental biology and medicine 20030901

• Morphological study of reparative processes in the gingiva during therapy of chronic periodontitis with energostim and application of orthopedic splinting constructions.

  Bulletin of experimental biology and medicine 20030901

• The reported human NADsyn2 is ammonia-dependent NAD synthetase from a pseudomonad.

  The Journal of biological chemistry 20030829

• Reversal of the deoxyhypusine synthesis reaction. Generation of spermidine or homospermidine from deoxyhypusine by deoxyhypusine synthase.

  The Journal of biological chemistry 20030829

• Interactions between transhydrogenase and thio-nicotinamide Analogues of NAD(H) and NADP(H) underline the importance of nucleotide conformational changes in coupling to proton translocation.

  The Journal of biological chemistry 20030829

• Inhibition of 11 beta-hydroxysteroid dehydrogenase type 2 by dithiocarbamates.

  Biochemical and biophysical research communications 20030822

• Thermodynamics and kinetics of the hydride-transfer cycles for 1-aryl-1,4-dihydronicotinamide and its 1,2-dihydroisomer.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030818

• An amperometric bi-enzyme sensor for determination of formate using cofactor regeneration.

  Biosensors & bioelectronics 20030815

• Chronic mild hypoxia protects heart-derived H9c2 cells against acute hypoxia/reoxygenation by regulating expression of the SUR2A subunit of the ATP-sensitive K+ channel.

  The Journal of biological chemistry 20030815

• Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry.

  Biochemistry 20030812

• Evidence for the role of a peroxidase compound I-type intermediate in the oxidation of glutathione, NADH, ascorbate, and dichlorofluorescin by cytochrome c/H2O2. Implications for oxidative stress during apoptosis.

  The Journal of biological chemistry 20030808

• Cofactor recycling mechanism in asymmetric biocatalytic reduction of carbonyl compounds mediated by yeast: which is the efficient electron donor?

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030804

• Extent of damage in ischemic, nonreperfused, and reperfused myocardium of anesthetized rats.

  American journal of physiology. Heart and circulatory physiology 20030801

• Evidence for the involvement of cell wall peroxidase in the generation of hydroxyl radicals mediating extension growth.

  Planta 20030801

• Interaction of oxidative stress and inflammatory response in coronary plaque instability: important role of C-reactive protein.

  Arteriosclerosis, thrombosis, and vascular biology 20030801

• Pyruvate modulates cardiac sarcoplasmic reticulum Ca2+ release in rats via mitochondria-dependent and -independent mechanisms.

  The Journal of physiology 20030801

• Nicotinamide attenuates focal ischemic brain injury in rats: with special reference to changes in nicotinamide and NAD+ levels in ischemic core and penumbra.

  Neurochemical research 20030801

• Oxygen solubilities of media used in electrochemical respiration measurements.

  Analytical biochemistry 20030801

• Tryptophan and the immune response.

  Immunology and cell biology 20030801

• Regulatory mechanisms in the interaction between carbohydrate and lipid oxidation during exercise.

  Acta physiologica Scandinavica 20030801

• Determination of the transglycosidation activity of NAD+ glycohydrolases with 4-(2'-alkyl-sulfanyl-vinyl)-pyridine derivatives generating chromophoric NAD+ analogs.

  Bioorganic chemistry 20030801

• Are poly(ADP-ribosyl)ation by PARP-1 and deacetylation by Sir2 linked?

  BioEssays : news and reviews in molecular, cellular and developmental biology 20030801

• Characteristics of NADH-dependent lipid peroxidation in sarcoplasmic reticulum of white shrimp, Litopenaeus vannamei, and freshwater prawn, Macrobrachium rosenbergii.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030801

• Oxidation of glyceraldehyde-3-phosphate dehydrogenase enhances its binding to nucleic acids.

  Biochemical and biophysical research communications 20030801

• POS5 gene of Saccharomyces cerevisiae encodes a mitochondrial NADH kinase required for stability of mitochondrial DNA.

  Eukaryotic cell 20030801

• Recent developments in pyridine nucleotide regeneration.

  Current opinion in biotechnology 20030801

• Endothelium and smooth muscle of pig coronary artery: differences in metabolism.

  Molecular and cellular biochemistry 20030801

• Cyanidin and cyanidin 3-O-beta-D -glucoside as DNA cleavage protectors and antioxidants.

  Cell biology and toxicology 20030801

• Cyclosporin A-insensitive permeability transition in brain mitochondria: inhibition by 2-aminoethoxydiphenyl borate.

  The Journal of biological chemistry 20030725

• Identification of regulatory domains in ADP-ribosyltransferase-1 that determine transferase and NAD glycohydrolase activities.

  The Journal of biological chemistry 20030718

• Differential modulation of cardiac and skeletal muscle ryanodine receptors by NADH.

  FEBS letters 20030717

• On-chip integration of enzyme and immunoassays: simultaneous measurements of insulin and glucose.

  Journal of the American Chemical Society 20030716

• Structure of xylose reductase bound to NAD+ and the basis for single and dual co-substrate specificity in family 2 aldo-keto reductases.

  The Biochemical journal 20030715

• Systemic poly(ADP-ribose) polymerase-1 activation, chronic inflammation, and oxidative stress in COPD patients.

  Free radical biology & medicine 20030715

• Brain mitochondria are primed by moderate Ca2+ rise upon hypoxia/reoxygenation for functional breakdown and morphological disintegration.

  The Journal of biological chemistry 20030711

• Physical and genetic interactions of cytosolic malate dehydrogenase with other gluconeogenic enzymes.

  The Journal of biological chemistry 20030711

• Stereospecific biocatalytic epoxidation: the first example of direct regeneration of a FAD-dependent monooxygenase for catalysis.

  Journal of the American Chemical Society 20030709

• Porin OmpP2 of Haemophilus influenzae shows specificity for nicotinamide-derived nucleotide substrates.

  The Journal of biological chemistry 20030704

• Skeletal muscle sarcoplasmic reticulum contains a NADH-dependent oxidase that generates superoxide.

  American journal of physiology. Cell physiology 20030701

• Electrochemical behavior of pyrroloquinoline quinone immobilized on silica gel modified with zirconium oxide.

  Journal of colloid and interface science 20030701

• In vitro metabolism of the mammalian soluble epoxide hydrolase inhibitor, 1-cyclohexyl-3-dodecyl-urea.

  Drug metabolism and disposition: the biological fate of chemicals 20030701

• Reconstructing eukaryotic NAD metabolism.

  BioEssays : news and reviews in molecular, cellular and developmental biology 20030701

• Mechanism of protection of peroxidase activity by oscillatory dynamics.

  European journal of biochemistry 20030701

• Structures of NAD(+)- and NADH-bound 1-l-myo-inositol 1-phosphate synthase.

  Acta crystallographica. Section D, Biological crystallography 20030701

• Expression, purification and crystallization of the Plasmodium falciparum enoyl reductase.

  Acta crystallographica. Section D, Biological crystallography 20030701

• Influence of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitors on endothelial nitric oxide synthase and the formation of oxidants in the vasculature.

  Atherosclerosis 20030701

• The effect of alcohol on blood glucose in Type 1 diabetes--metabolic modelling and integration in a decision support system.

  International journal of medical informatics 20030701

• Simultaneous detection of the antioxidant and pro-oxidant activity of dietary polyphenolics in a peroxidase system.

  Free radical research 20030701

• Transfer of pro-R hydrogen from NADH to dihydroxyacetonephosphate by sn-glycerol-1-phosphate dehydrogenase from the archaeon Methanothermobacter thermautotrophicus.

  Bioscience, biotechnology, and biochemistry 20030701

• Oxidoreductive capability of boar sperm mitochondria in fresh semen and during their preservation in BTS extender.

  Reproductive biology 20030701

• Impaired cortical energy metabolism but not major antioxidant defenses in experimental bacterial meningitis.

  Brain research 20030627

• Mechanism of xanthine oxidase catalyzed biotransformation of HMX under anaerobic conditions.

  Biochemical and biophysical research communications 20030627

• Coordinated production and utilization of FADH2 by NAD(P)H-flavin oxidoreductase and 4-hydroxyphenylacetate 3-monooxygenase.

  Biochemistry 20030624

• Superoxide stimulates a proton leak in potato mitochondria that is related to the activity of uncoupling protein.

  The Journal of biological chemistry 20030620

• Bio-mimetic hydrogen production from polysaccharide using the visible light sensitization of zinc porphyrin.

  Biotechnology and bioengineering 20030620

• Coenzyme isomerization is integral to catalysis in aldehyde dehydrogenase.

  Biochemistry 20030617

• Evidence for the two phosphate binding sites of an analogue of the thioacyl intermediate for the Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase-catalyzed reaction, from its crystal structure.

  Biochemistry 20030617

• Class I alcohol dehydrogenase is highly expressed in normal human mammary epithelium but not in invasive breast cancer: implications for breast carcinogenesis.

  Cancer research 20030615

• Proton translocation by transhydrogenase.

  FEBS letters 20030612

• Enhanced MTT-reducing activity under growth inhibition by resveratrol in CEM-C7H2 lymphocytic leukemia cells.

  Cancer letters 20030610

• Properties of the apo-form of the NADP(H)-binding domain III of proton-pumping Escherichia coli transhydrogenase: implications for the reaction mechanism of the intact enzyme.

  Biochimica et biophysica acta 20030605

• Roles of individual amino acids in helix 14 of the membrane domain of proton-translocating transhydrogenase from Escherichia coli as deduced from cysteine mutagenesis.

  Biochemistry 20030603

• Ovarian modulators of 11beta-hydroxysteroid dehydrogenase (11beta HSD) activity in follicular fluid from bovine and porcine large antral follicles and spontaneous ovarian cysts.

  Biology of reproduction 20030601

• Kinetic, spectroscopic and thermodynamic characterization of the Mycobacterium tuberculosis adrenodoxin reductase homologue FprA.

  The Biochemical journal 20030601

• Outlines for the definition of halotolerance/halophily in yeasts: Candida versatilis (halophila) CBS4019 as the archetype?

  FEMS yeast research 20030601

• Study on the use of NADH fluorescence measurements for monitoring wastewater treatment systems.

  Water research 20030601

• Quinol-based metabolic cycle for estrogens in rat liver microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20030601

• Interflavin electron transfer in human cytochrome P450 reductase is enhanced by coenzyme binding. Relaxation kinetic studies with coenzyme analogues.

  European journal of biochemistry 20030601

• Expression of Raldh2, Cyp26 and Hox-1 in normal and retinoic acid-treated Ciona intestinalis embryos.

  Gene expression patterns : GEP 20030601

• NADH supplementation decreases pinacidil-primed I K ATP in ventricular cardiomyocytes by increasing intracellular ATP.

  British journal of pharmacology 20030601

• Esterification of borate with NAD+ and NADH as studied by electrospray ionization mass spectrometry and 11B NMR spectroscopy.

  Journal of mass spectrometry : JMS 20030601

• Renal haemodynamics and natriuretic responses to intravenous administration of diadenosine tetraphosphate (Ap4A) and nicotinamide adenine dinucleotide (NAD) in rat.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20030601

• NMR spectra and potentiometry studies of aluminum(III) binding with coenzyme NAD+ in acidic aqueous solutions.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030601

• A FlashPlate assay for the identification of PARP-1 inhibitors.

  Journal of biomolecular screening 20030601

• Mitochondrials complex I activity is reduced in latent adriamycin-induced cardiomyopathy of rat.

  Molecular and cellular biochemistry 20030601

• Biliverdin reductase from the liver of Atlantic salmon (Salmo salar).

  Biochemistry. Biokhimiia 20030601

• Iron and CYP2E1-dependent oxidative stress and toxicity.

  Alcohol (Fayetteville, N.Y.) 20030601

• Leishmania mexicana glycerol-3-phosphate dehydrogenase showed conformational changes upon binding a bi-substrate adduct.

  Journal of molecular biology 20030530

• Absence of evidence for metabolite-modulated association between alpha-glycerol-3-phosphate dehydrogenase and L-lactate dehydrogenase.

  Biochemistry 20030527

• Crystal structure of Thermotoga maritima alpha-glucosidase AglA defines a new clan of NAD+-dependent glycosidases.

  The Journal of biological chemistry 20030523

• The crystal structure and stereospecificity of levodione reductase from Corynebacterium aquaticum M-13.

  The Journal of biological chemistry 20030523

• The 2.3-A crystal structure of the shikimate 5-dehydrogenase orthologue YdiB from Escherichia coli suggests a novel catalytic environment for an NAD-dependent dehydrogenase.

  The Journal of biological chemistry 20030523

• Poly(ADP-ribose) polymerase-1 is a positive regulator of the p53-mediated G1 arrest response following ionizing radiation.

  The Journal of biological chemistry 20030523

• The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria.

  The Journal of biological chemistry 20030523

• Reversible, electrochemical interconversion of NADH and NAD+ by the catalytic (Ilambda) subcomplex of mitochondrial NADH:ubiquinone oxidoreductase (complex I).

  Journal of the American Chemical Society 20030521

• Insights into the evolution of allosteric properties. The NADH binding site of hexameric type II citrate synthases.

  Biochemistry 20030520

• Inactivation of S-adenosyl-L-homocysteine hydrolase with novel 5'-thioadenosine derivatives. Antiviral effects.

  Bioorganic & medicinal chemistry letters 20030519

• Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress.

  The Journal of biological chemistry 20030516

• Role of redox signaling in the autonomous proliferative response of endothelial cells to hypoxia.

  Circulation research 20030516

• Recycling of vitamin C from its oxidized forms by human endothelial cells.

  Biochimica et biophysica acta 20030512

• Longevity research. Single signal unites treatments that prolong life.

  Science (New York, N.Y.) 20030509

• 1H and 13C NMR characterization of hemiamidal isoniazid-NAD(H) adducts as possible inhibitors of InhA reductase of Mycobacterium tuberculosis.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030509

• Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae.

  Nature 20030508

• Changes in actomyosin ATP consumption rate in rat diaphragm muscle fibers during postnatal development.

  Journal of applied physiology (Bethesda, Md. : 1985) 20030501

• Expression profile of the transient receptor potential (TRP) family in neutrophil granulocytes: evidence for currents through long TRP channel 2 induced by ADP-ribose and NAD.

  The Biochemical journal 20030501

• Characterization of the intracellular calcium store at the base of the sperm flagellum that regulates hyperactivated motility.

  Biology of reproduction 20030501

• The catalytic mechanism of Drosophila alcohol dehydrogenase: evidence for a proton relay modulated by the coupled ionization of the active site Lysine/Tyrosine pair and a NAD+ ribose OH switch.

  Proteins 20030501

• Mechanistic and comparative studies of melatonin and classic antioxidants in terms of their interactions with the ABTS cation radical.

  Journal of pineal research 20030501

• A dual role for poly-ADP-ribosylation in spatial memory acquisition after traumatic brain injury in mice involving NAD+ depletion and ribosylation of 14-3-3gamma.

  Journal of neurochemistry 20030501

• Purification and partial characterization of azoreductase from Enterobacter agglomerans.

  Archives of biochemistry and biophysics 20030501

• Screen-printed electrodes with electropolymerized Meldola Blue as versatile detectors in biosensors.

  Biosensors & bioelectronics 20030501

• Cytoprotection of pyruvic acid and reduced beta-nicotinamide adenine dinucleotide against hydrogen peroxide toxicity in neuroblastoma cells.

  Neurochemical research 20030501

• Cinnamic acid 4-hydroxylase from cell cultures of the hornwort Anthoceros agrestis.

  Planta 20030501

• Significantly enhanced stability of glucose dehydrogenase by directed evolution.

  Applied microbiology and biotechnology 20030501

• The oxygenase component of phenol hydroxylase from Acinetobacter radioresistens S13.

  European journal of biochemistry 20030501

• Superoxide synthase and dismutase activity of plasma membranes from maize roots.

  Protoplasma 20030501

• Redox-related peroxidative responses evoked by methyl-jasmonate in axenically cultured aeroponic sunflower (Helianthus annuus L.) seedling roots.

  Protoplasma 20030501

• Microanatomical and biochemical origins of normal and precancerous cervical autofluorescence using laser-scanning fluorescence confocal microscopy.

  Photochemistry and photobiology 20030501

• Purification and characterization of two NAD-dependent alcohol dehydrogenases (ADHs) induced in the quinoprotein ADH-deficient mutant of Acetobacter pasteurianus SKU1108.

  Bioscience, biotechnology, and biochemistry 20030501

• A history of research on yeasts 5: the fermentation pathway.

  Yeast (Chichester, England) 20030430

• Dual coenzyme specificity of photosynthetic glyceraldehyde-3-phosphate dehydrogenase interpreted by the crystal structure of A4 isoform complexed with NAD.

  Biochemistry 20030429

• Crystal structure of GDP-mannose dehydrogenase: a key enzyme of alginate biosynthesis in P. aeruginosa.

  Biochemistry 20030429

• Mechanisms of electron-transfer oxidation of NADH analogues and chemiluminescence. Detection of the keto and enol radical cations.

  Journal of the American Chemical Society 20030423

• Polysiloxane-supported NAD(P)H model 1-benzyl-1,4-dihydronicotinamide: synthesis and application in the reduction of activated olefins.

  The Journal of organic chemistry 20030418

• Dextran causes aggregation of mitochondria and influences their oxidoreductase activities and light scattering.

  Archives of biochemistry and biophysics 20030415

• 'Mitochondrial' photochemical drugs do not release toxic amounts of 1O(2) within the mitochondrial matrix space.

  Archives of biochemistry and biophysics 20030415

• Glucocorticoids inhibit interconversion of 7-hydroxy and 7-oxo metabolites of dehydroepiandrosterone: a role for 11beta-hydroxysteroid dehydrogenases?

  Archives of biochemistry and biophysics 20030415

• NAD(P)H fluorescence imaging of postsynaptic neuronal activation in murine hippocampal slices.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415

• Homologous binding sites in yeast isocitrate dehydrogenase for cofactor (NAD+) and allosteric activator (AMP).

  The Journal of biological chemistry 20030411

• Structural characterization of a human cytosolic NMN/NaMN adenylyltransferase and implication in human NAD biosynthesis.

  The Journal of biological chemistry 20030411

• Measurement of the kinetic isotope effect for the oxidation of NADH at a poly(aniline)-modified electrode.

  Journal of the American Chemical Society 20030409

• Biochemical and genetic characterization of a novel enzyme of pentitol metabolism: D-arabitol-phosphate dehydrogenase.

  The Biochemical journal 20030401

• Nicotinamide adenine dinucleotide, a metabolic regulator of transcription, longevity and disease.

  Current opinion in cell biology 20030401

• Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation.

  Biochemistry 20030401

• Oxygen control of nif gene expression in Klebsiella pneumoniae depends on NifL reduction at the cytoplasmic membrane by electrons derived from the reduced quinone pool.

  European journal of biochemistry 20030401

• Inhibition of mitochondrial Na+-Ca2+ exchanger increases mitochondrial metabolism and potentiates glucose-stimulated insulin secretion in rat pancreatic islets.

  Diabetes 20030401

• Alpha-5,6-dimethylbenzimidazole adenine dinucleotide (alpha-DAD), a putative new intermediate of coenzyme B12 biosynthesis in Salmonella typhimurium.

  Microbiology (Reading, England) 20030401

• Phloem metabolism and function have to cope with low internal oxygen.

  Plant physiology 20030401

• Prerigor injection using glycolytic inhibitors in low-quality beef muscles.

  Journal of animal science 20030401

• Purification and characterization of formate dehydrogenase from Ancylobacter aquaticus strain KNK607M, and cloning of the gene.

  Bioscience, biotechnology, and biochemistry 20030401

• [Reversibility of the effects of cadmium on the growth and nitrogen metabolism in the tomato(Lycopersicon esculentum)].

  Comptes rendus biologies 20030401

• Denaturation studies by fluorescence and quenching of thermophilic protein NAD+-glutamate dehydrogenase from Thermus thermophilus HB8.

  Journal of protein chemistry 20030401

• Molecular identification of human glutamine- and ammonia-dependent NAD synthetases. Carbon-nitrogen hydrolase domain confers glutamine dependency.

  The Journal of biological chemistry 20030328

• Glutamate-115 renders specificity of human 11beta-hydroxysteroid dehydrogenase type 2 for the cofactor NAD+.

  Molecular and cellular endocrinology 20030328

• The crystal structure of R-specific alcohol dehydrogenase from Lactobacillus brevis suggests the structural basis of its metal dependency.

  Journal of molecular biology 20030321

• Amino acid residues in the nicotinamide binding site contribute to catalysis by horse liver alcohol dehydrogenase.

  Biochemistry 20030318

• Characterization of Streptococcus pneumoniae enoyl-(acyl-carrier protein) reductase (FabK).

  The Biochemical journal 20030315

• On noxious desmin: functional effects of a novel heterozygous desmin insertion mutation on the extrasarcomeric desmin cytoskeleton and mitochondria.

  Human molecular genetics 20030315

• Ligand-induced conformational changes and a mechanism for domain closure in Aspergillus nidulans dehydroquinate synthase.

  Journal of molecular biology 20030314

• P but not R-axis interface is involved in cooperative binding of NAD on tetrameric phosphorylating glyceraldehyde-3-phosphate dehydrogenase from Bacillus stearothermophilus.

  Journal of molecular biology 20030307

• Two EPR-detectable [4Fe-4S] clusters, N2a and N2b, are bound to the NuoI (TYKY) subunit of NADH:ubiquinone oxidoreductase (Complex I) from Rhodobacter capsulatus.

  Biochimica et biophysica acta 20030306

• Electromagnetic field generation by ATP-induced reverse electron transfer.

  Archives of biochemistry and biophysics 20030301

• Chromaffin cell death induced by 6-hydroxydopamine is independent of mitochondrial swelling and caspase activation.

  Journal of neurochemistry 20030301

• MPP(+) causes inhibition of cellular energy supply in cerebellar granule cells.

  Neurotoxicology 20030301

• The expanding network of redox signaling: new observations, complexities, and perspectives.

  The Journal of clinical investigation 20030301

• 2-Oxo acid dehydrogenase complexes in redox regulation.

  European journal of biochemistry 20030301

• Reduction of S-nitrosoglutathione by human alcohol dehydrogenase 3 is an irreversible reaction as analysed by electrospray mass spectrometry.

  European journal of biochemistry 20030301

• Purification of a plant nucleotide pyrophosphatase as a protein that interferes with nitrate reductase and glutamine synthetase assays.

  European journal of biochemistry 20030301

• Regulation of the aerobic respiratory chain in the facultatively aerobic and hyperthermophilic archaeon Pyrobaculum oguniense.

  Microbiology (Reading, England) 20030301

• Responsiveness of renal glomeruli to adenosine in streptozotocin-induced diabetic rats dependent on hyperglycaemia level.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20030301

• Molecular engineering of proteins with predefined function. Part I: Design of a hemoglobin-based oxygen carrier.

  Biomolecular engineering 20030301

• Phenothiazine radicals inactivate Trypanosoma cruzi dihydrolipoamide dehydrogenase: enzyme protection by radical scavengers.

  Free radical research 20030301

• Beneficial effects of poly (ADP-ribose) polymerase inhibition against the reperfusion injury in heart transplantation.

  Free radical research 20030301

• Engineering of the metabolism of Saccharomyces cerevisiae for anaerobic production of mannitol.

  FEMS yeast research 20030301

• Nicotinamide adenine dinucleotide stimulates oligomerization, interaction with adenovirus E1A and an intrinsic dehydrogenase activity of CtBP.

  FEBS letters 20030227

• Enzymatic method for assaying calcium in serum with Ca++ -ATPase.

  Experimental & molecular medicine 20030227

• Catalytic strategy of S-adenosyl-L-homocysteine hydrolase: transition-state stabilization and the avoidance of abortive reactions.

  Biochemistry 20030225

• Catalysis of diaphorase reactions by Mycobacterium tuberculosis lipoamide dehydrogenase occurs at the EH4 level.

  Biochemistry 20030225

• Aqueous access channels in subunit a of rotary ATP synthase.

  The Journal of biological chemistry 20030221

• Sera from cancer patients contain two oscillating ECTO-NOX activities with different period lengths.

  Cancer letters 20030220

• Determination of the C4-H bond dissociation energies of NADH models and their radical cations in acetonitrile.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030217

• Selenite sensitizes mitochondrial permeability transition pore opening in vitro and in vivo: a possible mechanism for chemo-protection.

  The Biochemical journal 20030215

• External alternative NADH dehydrogenase of Saccharomyces cerevisiae: a potential source of superoxide.

  Free radical biology & medicine 20030215

• Cytochrome c-induced cytosolic nicotinamide adenine dinucleotide oxidation, mitochondrial permeability transition, and apoptosis.

  Archives of biochemistry and biophysics 20030215

• A spectrophotometric method to quantify linear DNA.

  Analytical biochemistry 20030215

• Continuous spectrophotometric assay amenable to 96-well plate format for prostaglandin E synthase activity.

  Analytical biochemistry 20030215

• Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism.

  Journal of molecular biology 20030214

• Glutamine 132 in the NAD(H)-binding component of proton-translocating transhydrogenase tethers the nucleotides before hydride transfer.

  Biochemistry 20030211

• Role of Thr(66) in porcine NADH-cytochrome b5 reductase in catalysis and control of the rate-limiting step in electron transfer.

  The Journal of biological chemistry 20030207

• The transition between active and de-activated forms of NADH:ubiquinone oxidoreductase (Complex I) in the mitochondrial membrane of Neurospora crassa.

  The Biochemical journal 20030201

• Mitochondrial respiration and Ca2+ waves are linked during fertilization and meiosis completion.

  Development (Cambridge, England) 20030201

• Exploring the interaction energies for the binding of hydroxydiphenyl ethers to enoyl-acyl carrier protein reductases.

  Journal of biomolecular structure & dynamics 20030201

• Role of calcium in metabolic signaling between cardiac sarcoplasmic reticulum and mitochondria in vitro.

  American journal of physiology. Cell physiology 20030201

• Preconditioning with sevoflurane reduces changes in nicotinamide adenine dinucleotide during ischemia-reperfusion in isolated hearts: reversal by 5-hydroxydecanoic acid.

  Anesthesiology 20030201

• Inhibition of NADH oxidation by chloramphenicol in the freely moving rat measured by picosecond time-resolved emission spectroscopy.

  Journal of neurochemistry 20030201

• Simultaneous determination of purine nucleotides, their metabolites and beta-nicotinamide adenine dinucleotide in cerebellar granule cells by ion-pair high performance liquid chromatography.

  Brain research. Brain research protocols 20030201

• Photochemical and photobiological studies of tirapazamine (SR 4233) and related quinoxaline 1,4-Di-N-oxide analogues.

  Chemical research in toxicology 20030201

• Identification and characterization of a second NMN adenylyltransferase gene in Saccharomyces cerevisiae.

  Protein expression and purification 20030201

• Chemical modifications to study mutations that affect the ability of the general base (E268) to function in human liver mitochondrial aldehyde dehydrogenase.

  Chemico-biological interactions 20030201

• Crystal structure of glutathione-independent formaldehyde dehydrogenase.

  Chemico-biological interactions 20030201

• Tetrameric NAD-dependent alcohol dehydrogenase.

  Chemico-biological interactions 20030201

• Differential pyridine nucleotide coenzyme binding to the beta-subunit of the voltage-sensitive K+ channel: a mechanism for redox regulation of excitability?

  Chemico-biological interactions 20030201

• Indigo production by Escherichia coli carrying the phenol hydroxylase gene from Acinetobacter sp strain ST-550 in a water-organic solvent two-phase system.

  Applied microbiology and biotechnology 20030201

• Exposure-disease continuum for 2-chloro-2'-deoxyadenosine, a prototype ocular teratogen. 3. Intervention with PK11195.

  Birth defects research. Part A, Clinical and molecular teratology 20030201

• Metabolic flux analysis of RQ-controlled microaerobic ethanol production by Saccharomyces cerevisiae.

  Yeast (Chichester, England) 20030130

• The ND5 subunit was labeled by a photoaffinity analogue of fenpyroximate in bovine mitochondrial complex I.

  Biochemistry 20030128

• Kynurenines and the respiratory parameters on rat heart mitochondria.

  Life sciences 20030124

• Molecular recognition in (+)-alpha-pinene oxidation by cytochrome P450cam.

  Journal of the American Chemical Society 20030122

• The role of oxoammonium cation in the SOD-mimic activity of cyclic nitroxides.

  Journal of the American Chemical Society 20030122

• Crystal structure and site-directed mutagenesis of enzymatic components from Clostridium perfringens iota-toxin.

  Journal of molecular biology 20030117

• Role of anthocyanidin reductase, encoded by BANYULS in plant flavonoid biosynthesis.

  Science (New York, N.Y.) 20030117

• Subcellular alteration of glyceraldehyde-3-phosphate dehydrogenase in Alzheimer's disease fibroblasts.

  Journal of neuroscience research 20030115

• Biosynthesis of 4-methylproline in cyanobacteria: cloning of nosE and nosF genes and biochemical characterization of the encoded dehydrogenase and reductase activities.

  The Journal of organic chemistry 20030110

• Hydride-exchange reactions between NADH and NAD+ model compounds under non-steady-state conditions. Apparent and real kinetic isotope effects.

  Organic & biomolecular chemistry 20030107

• Mechanism and substrate specificity of the flavin reductase ActVB from Streptomyces coelicolor.

  The Journal of biological chemistry 20030103

• Is neuroprotective efficacy of nNOS inhibitor 7-NI dependent on ischemic intracellular pH?

  American journal of physiology. Heart and circulatory physiology 20030101

• Transendothelial migration leads to protection from starvation-induced apoptosis in CD34+CD14+ circulating precursors: evidence for PECAM-1 involvement through Akt/PKB activation.

  Blood 20030101

• Aliphatic epoxide carboxylation.

  Annual review of biochemistry 20030101

• Tryptophan availability selectively limits NO-synthase induction in macrophages.

  Journal of leukocyte biology 20030101

• Biohydrogen production from sucrose using the visible light sensitization of artificial Zn chlorophyll-a.

  Bioconjugate chemistry 20030101

• The response of Leuconostoc mesenteroides to low external oxidoreduction potential generated by hydrogen gas.

  Journal of applied microbiology 20030101

• Effect of prenatal exposure to hydroxyprogesterone on steroidogenic enzymes in male rats.

  Die Naturwissenschaften 20030101

• The effect of carbon sources and lactate dehydrogenase deletion on 1,2-propanediol production in Escherichia coli.

  Journal of industrial microbiology & biotechnology 20030101

• Mutagenic activation of arylamines by subcellular fractions of Chamaelea gallina clams exposed to environmental pollutants.

  Environmental and molecular mutagenesis 20030101

• The tungsten-containing formate dehydrogenase from Methylobacterium extorquens AM1: purification and properties.

  European journal of biochemistry 20030101

• [Xanthine dehydrogenase (xanthine oxidase)].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• Different sensitivities of mutants and chimeric forms of human muscle and liver fructose-1,6-bisphosphatases towards AMP.

  Biological chemistry 20030101

• [Regulation of acetate metabolism in a strain of Acinetobacter sp., growing on ethanol].

  Prikladnaia biokhimiia i mikrobiologiia 20030101

• Role and regulation of TRP channels in neutrophil granulocytes.

  Cell calcium 20030101

• Clostridium perfringens iota-toxin, ADP-ribosyltransferase: structure and mechanism of action.

  Advances in enzyme regulation 20030101

• Chronic DNA damage and niacin deficiency enhance cell injury and cause unusual interactions in NAD and poly(ADP-ribose) metabolism in rat bone marrow.

  Nutrition and cancer 20030101

• Colorimetric dehydrogenase screen based on NAD(P)H generation.

  Methods in molecular biology (Clifton, N.J.) 20030101

• Hypoxia-induced modification of poly (ADP-ribose) polymerase and dna polymerase beta activity in cerebral cortical nuclei of newborn piglets: role of nitric oxide.

  Neuroscience 20030101

• Coenzyme Q releases the inhibitory effect of free fatty acids on mitochondrial glycerophosphate dehydrogenase.

  Acta biochimica Polonica 20030101

• Modulation of the voltage-dependent anion-selective channel by cytoplasmic proteins from wild type and the channel depleted cells of Saccharomyces cerevisiae.

  Acta biochimica Polonica 20030101

• Starvation-induced impairment of metabolism in a freshwater catfish.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101

• Arrest of cell cycle by inhibition of ribonucleotide reductase induces accumulation of NAD+ by Mn2+-supplemented growth of Corynebacterium ammoniagenes.

  Biotechnology letters 20030101

• Characterization of NADH: nitrate reductase from the coccolithophorid Emiliania huxleyi (Lohman) Hay & Mohler (Haptophyceae).

  Marine biotechnology (New York, N.Y.) 20030101

• IMP dehydrogenase: the dynamics of drug selectivity.

  Nucleic acids research. Supplement (2001) 20030101

• [The activity of xylose reductase and xylitol dehydrogenase in yeasts].

  Mikrobiologiia 20030101

• [Biochemical characterization of the yeast Yarrowia lipolytica overproducing carboxylic acids from ethanol. Nitrogen metabolism enzymes].

  Mikrobiologiia 20030101

• Reductive metabolism of the nitroimidazole-based hypoxia-selective cytotoxin NLCQ-1 (NSC 709257).

  Oncology research 20030101

• Stereocontrolled synthesis of diene and enyne sugar-modified nucleosides and their interaction with S-adenosyl-L-homocysteine hydrolase.

  Nucleosides, nucleotides & nucleic acids 20030101

• Cyclosporin A-sensitive cytochrome c release and activation of external pathway of NADH oxidation in liver mitochondria due to pore opening by acidification of phosphate-containing incubation medium.

  Bioscience reports 20030101

• Nature and mode of action of NAD and ATP dephosphorylating enzyme from Aspergillus terreus DSM 826.

  Antonie van Leeuwenhoek 20030101

• Pathophysiological aspects of cellular pyridine nucleotide metabolism: focus on the vascular endothelium. Review.

  Acta physiologica Hungarica 20030101

• Single dose of glutamine enhances myocardial tissue metabolism, glutathione content, and improves myocardial function after ischemia-reperfusion injury.

  JPEN. Journal of parenteral and enteral nutrition 20030101

• 3D QSAR studies on binding affinities of coumarin natural products for glycosomal GAPDH of Trypanosoma cruzi.

  Journal of computer-aided molecular design 20030101

• [Effect of energostim on myocardial damage during coronary artery occlusion].

  Eksperimental'naia i klinicheskaia farmakologiia 20030101

• [Effect of nickel compounds on glutathione-dependent antioxidant system of pea and maize shoots].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20030101

• Niacin and carcinogenesis.

  Nutrition and cancer 20030101

• Specificity of coenzyme Q inhibition of an aging-related cell surface NADH oxidase (ECTO-NOX) that generates superoxide.

  BioFactors (Oxford, England) 20030101

• Hepatocyte metabolism of coenzyme Q1 (ubiquinone-5) to its sulfate conjugate decreases its antioxidant activity.

  BioFactors (Oxford, England) 20030101

• Acrolein inhibits NADH-linked mitochondrial enzyme activity: implications for Alzheimer's disease.

  Neurotoxicity research 20030101

• Cytotoxicity and apoptosis induction by butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT).

  Anticancer research 20030101

• Antiangiogenic potency of FK866/K22.175, a new inhibitor of intracellular NAD biosynthesis, in murine renal cell carcinoma.

  Anticancer research 20030101

• Mechanosensing and signal transduction in tendrils.

  Advances in space research : the official journal of the Committee on Space Research (COSPAR) 20030101

• Recent advances in physiological and pathological significance of tryptophan-NAD+ metabolites: lessons from insulin-producing pancreatic beta-cells.

  Advances in experimental medicine and biology 20030101

• NAD levels in the rat primary cultured hepatocytes affected by peroxisome-proliferators.

  Advances in experimental medicine and biology 20030101

• The effects of phthalate esters on the tryptophan-niacin metabolism.

  Advances in experimental medicine and biology 20030101

• Application of NAD-dependent polyol dehydrogenases for enzymatic mannitol/sorbitol production with coenzyme regeneration.

  Communications in agricultural and applied biological sciences 20030101

• Mobility of fluorobenzyl alcohols bound to liver alcohol dehydrogenases as determined by NMR and X-ray crystallographic studies.

  Biochemistry 20021231

• Expression and characterization of ferredoxin and flavin adenine dinucleotide binding domains of the reductase component of soluble methane monooxygenase from Methylococcus capsulatus (Bath).

  Biochemistry 20021231

• Pertussis toxin-insensitive activation of the heterotrimeric G-proteins Gi/Go by the NG108-15 G-protein activator.

  The Journal of biological chemistry 20021227

• Human glutathione-dependent formaldehyde dehydrogenase. Structural changes associated with ternary complex formation.

  Biochemistry 20021224

• New UDP-GlcNAc C4 epimerase involved in the biosynthesis of 2-acetamino-2-deoxy-L-altruronic acid in the O-antigen repeating units of Plesiomonas shigelloides O17.

  Biochemistry 20021224

• Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine.

  Science (New York, N.Y.) 20021220

• Optimizing the enzymatic determination of galactose in the culture medium of rat liver and HepG2 cell spheroids.

  Analytical biochemistry 20021215

• Modification of the nucleotide cofactor-binding site of cytochrome P-450 reductase to enhance turnover with NADH in Vivo.

  The Journal of biological chemistry 20021213

• Characterization of a novel enoyl-acyl carrier protein reductase of diazaborine-resistant Rhodobacter sphaeroides mutant.

  Biochemical and biophysical research communications 20021213

• Direct detection of radical cations of NADH analogues.

  Journal of the American Chemical Society 20021211

• Roles of the proximal hydrogen bonding network in cytochrome P450cam-catalyzed oxygenation.

  Journal of the American Chemical Society 20021211

• The lipoamide dehydrogenase from Mycobacterium tuberculosis permits the direct observation of flavin intermediates in catalysis.

  Biochemistry 20021210

• Extracellular NAD+: a novel autocrine/paracrine signal in osteoblast physiology.

  Biochemical and biophysical research communications 20021206

• Oxidative DNA damage by a common metabolite of carcinogenic nitrofluorene and N-acetylaminofluorene.

  International journal of cancer 20021201

• Development of a quantitative assay method for 3 beta-hydroxy-delta 5-steroid dehydrogenase in the rat testis.

  Steroids 20021201

• Inhibition of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by cyclooxygenase inhibitors and chemopreventive agents.

  Prostaglandins, leukotrienes, and essential fatty acids 20021201

• Verification of a novel NADH-binding motif: combinatorial mutagenesis of three amino acids in the cofactor-binding pocket of Corynebacterium 2,5-diketo-D-gluconic acid reductase.

  Journal of molecular evolution 20021201

• Purification and characterization of the complex I from the respiratory chain of Rhodothermus marinus.

  Journal of bioenergetics and biomembranes 20021201

• NADH is specifically channeled through the mitochondrial porin channel in Saccharomyces cerevisiae.

  Journal of bioenergetics and biomembranes 20021201

• The key role of the energized state of Saccharomyces cerevisiae mitochondria in modulations of the outer membrane channels by the intermembrane space proteins.

  Journal of bioenergetics and biomembranes 20021201

• T cells of different developmental stages differ in sensitivity to apoptosis induced by extracellular NAD.

  Developmental immunology 20021201

• Insight into the catalytic mechanism of Pseudomonas aeruginosa exotoxin A. Studies of toxin interaction with eukaryotic elongation factor-2.

  The Journal of biological chemistry 20021129

• Crystal structure of formaldehyde dehydrogenase from Pseudomonas putida: the structural origin of the tightly bound cofactor in nicotinoprotein dehydrogenases.

  Journal of molecular biology 20021129

• Dual-substrate specificity short chain retinol dehydrogenases from the vertebrate retina.

  The Journal of biological chemistry 20021122

• The C-terminal extension of glyceraldehyde-3-phosphate dehydrogenase subunit B acts as an autoinhibitory domain regulated by thioredoxins and nicotinamide adenine dinucleotide.

  The Journal of biological chemistry 20021122

• The effects of nicotinamide on energy metabolism following transient focal cerebral ischemia in Wistar rats.

  Neuroscience letters 20021122

• Identification of the first fungal NADP-GAPDH from Kluyveromyces lactis.

  Biochemistry 20021119

• Purification and kinetic properties of UDP-glucose dehydrogenase from sugarcane.

  Archives of biochemistry and biophysics 20021115

• Thermostable aldehyde dehydrogenase from psychrophile, Cytophaga sp. KUC-1: enzymological characteristics and functional properties.

  Biochemical and biophysical research communications 20021115

• Is reduction of the sulfonated tetrazolium 2,3-bis (2-methoxy-4-nitro-5-sulfophenyl)-2-tetrazolium 5-carboxanilide a reliable measure of intracellular superoxide production?

  Analytical biochemistry 20021115

• Extracellular metabolisation of NADH by blood cells correlates with intracellular ATP levels.

  Biochimica et biophysica acta 20021114

• Idiosyncratic NSAID drug induced oxidative stress.

  Chemico-biological interactions 20021110

• Crystal structure of Pseudomonas fluorescens mannitol 2-dehydrogenase binary and ternary complexes. Specificity and catalytic mechanism.

  The Journal of biological chemistry 20021108

• Novel tricyclic poly(ADP-ribose) polymerase-1 inhibitors with potent anticancer chemopotentiating activity: design, synthesis, and X-ray cocrystal structure.

  Journal of medicinal chemistry 20021107

• NADH model systems functionalized with Zn(II)-cyclen as flavin binding site-structure dependence of the redox reaction within reversible aggregates.

  Journal of the American Chemical Society 20021106

• Crystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis.

  Biochemistry 20021105

• Switch to anaerobic glucose metabolism with NADH accumulation in the beta-cell model of mitochondrial diabetes. Characteristics of betaHC9 cells deficient in mitochondrial DNA transcription.

  The Journal of biological chemistry 20021101

• Importance of glutamate 279 for the coenzyme binding of human glutamate dehydrogenase.

  The Journal of biological chemistry 20021101

• Regulation of alternative oxidase gene expression in soybean.

  Plant molecular biology 20021101

• Protection of focal cerebral ischemia by alkalinization of systemic pH.

  Neurosurgery 20021101

• Inhibitors of poly(ADP-ribose) polymerase-1 suppress transcriptional activation in lymphocytes and ameliorate autoimmune encephalomyelitis in rats.

  British journal of pharmacology 20021101

• Halothane, isoflurane and sevoflurane inhibit NADH:ubiquinone oxidoreductase (complex I) of cardiac mitochondria.

  The Journal of physiology 20021101

• Expression and purification of the recombinant subunits of toluene/o-xylene monooxygenase and reconstitution of the active complex.

  European journal of biochemistry 20021101

• Formation of pyridine nucleotides under symbiotic and non-symbiotic conditions between soybean nodules and free-living rhizobia.

  Phytochemistry 20021101

• Dehydrogenases, NAD, and transcription--what's the connection?

  Structure (London, England : 1993) 20021101

• Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis.

  European journal of immunology 20021101

• Role of mitochondrial NADH shuttle system in acute amylase secretion by acetylcholine from mouse pancreatic acinar cells.

  The Tohoku journal of experimental medicine 20021101

• Inhibitors of the IMPDH enzyme as potential anti-bovine viral diarrhoea virus agents.

  Antiviral chemistry & chemotherapy 20021101

• Purification of glutamate dehydrogenase from liver and brain.

  Current protocols in protein science 20021101

• Niacin deficiency increases spontaneous and etoposide-induced chromosomal instability in rat bone marrow cells in vivo.

  Mutation research 20021031

• CYP119 plus a Sulfolobus tokodaii strain 7 ferredoxin and 2-oxoacid:ferredoxin oxidoreductase constitute a high-temperature cytochrome P450 catalytic system.

  Journal of the American Chemical Society 20021030

• Scandium ion-promoted reduction of heterocyclic N=N double bond. Hydride transfer vs electron transfer.

  Journal of the American Chemical Society 20021023

• Crystal structures of transhydrogenase domain I with and without bound NADH.

  Biochemistry 20021022

• Cofactor binding to Escherichia coli D-3-phosphoglycerate dehydrogenase induces multiple conformations which alter effector binding.

  The Journal of biological chemistry 20021018

• Development of a fluorescence resonance energy transfer assay for measuring the activity of Streptococcus pneumoniae DNA ligase, an enzyme essential for DNA replication, repair, and recombination.

  Analytical biochemistry 20021015

• Tartrate dehydrogenase catalyzes the stepwise oxidative decarboxylation of D-malate with both NAD and thio-NAD.

  Biochemistry 20021008

• Atropoisomeric quinolinium salt promoting the access to both enantiomeric forms of methyl mandelate: a versatile NADH mimic.

  Chemical communications (Cambridge, England) 20021007

• Identification of a novel human nicotinamide mononucleotide adenylyltransferase.

  Biochemical and biophysical research communications 20021004

• A novel cycling assay for nicotinic acid-adenine dinucleotide phosphate with nanomolar sensitivity.

  The Biochemical journal 20021001

• Identification of cofactor discrimination sites in NAD-isocitrate dehydrogenase from Pyrococcus furiosus.

  Archives of microbiology 20021001

• Reverse flux through cardiac NADP(+)-isocitrate dehydrogenase under normoxia and ischemia.

  American journal of physiology. Heart and circulatory physiology 20021001

• Pyruvate improves redox status and decreases indicators of hepatic apoptosis during hemorrhagic shock in swine.

  American journal of physiology. Heart and circulatory physiology 20021001

• Ca(2+)-induced high amplitude swelling and cytochrome c release from wheat (Triticum aestivum L.) mitochondria under anoxic stress.

  Annals of botany 20021001

• Role of NADH shuttles in glucose-induced insulin secretion from fetal beta-cells.

  Diabetes 20021001

• Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species.

  European journal of biochemistry 20021001

• Effects of euthanasia on brain physiological activities monitored in real-time.

  Neurological research 20021001

• Effects of the nitric oxide donor 3-morpholinosydnonimine (SIN-1) in focal cerebral ischemia dependent on intracellular brain pH.

  Journal of neurosurgery 20021001

• Transcription corepressor CtBP is an NAD(+)-regulated dehydrogenase.

  Molecular cell 20021001

• The role of NADPH oxidase and neuronal nitric oxide synthase in zinc-induced poly(ADP-ribose) polymerase activation and cell death in cortical culture.

  Experimental neurology 20021001

• Real-time determination of glucose consumption by live cells using a lab-on-valve system with an integrated microbioreactor.

  The Analyst 20021001

• Glucose metabolism of lactic acid bacteria changed by quinone-mediated extracellular electron transfer.

  Bioscience, biotechnology, and biochemistry 20021001

• Mathematical modeling of in vitro enzymatic production of 2-Keto-L-gulonic acid using NAD(H) or NADP(H) as cofactors.

  Metabolic engineering 20021001

• Effect of the inhibition of the metabolism of 4-vinylphenol on its hepatotoxicity and pneumotoxicity in rats and mice.

  Toxicology 20020930

• Reductive activation of dioxygen by a myoglobin reconstituted with a flavohemin.

  Journal of the American Chemical Society 20020925

• Physiological role of soluble fumarate reductase in redox balancing during anaerobiosis in Saccharomyces cerevisiae.

  FEMS microbiology letters 20020924

• Molecular, biochemical, and functional characterization of a Nudix hydrolase protein that stimulates the activity of a nicotinoprotein alcohol dehydrogenase.

  The Journal of biological chemistry 20020920

• Detection of multiple active site domain motions in transient-state component time courses of the Clostridium symbiosum L-glutamate dehydrogenase-catalyzed oxidative deamination reaction.

  Biochemistry 20020917

• Catalytic reaction profile for NADH-dependent reduction of aromatic aldehydes by xylose reductase from Candida tenuis.

  The Biochemical journal 20020915

• Anionic substitutes for catalytic aspartic acids in phosphoribulokinase.

  Archives of biochemistry and biophysics 20020915

• Thiazolidinediones as a novel class of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.

  Archives of biochemistry and biophysics 20020915

• Reduced flavins promote oxidative DNA damage in non-respiring Escherichia coli by delivering electrons to intracellular free iron.

  The Journal of biological chemistry 20020913

• The B' helix determines cytochrome P450nor specificity for the electron donors NADH and NADPH.

  The Journal of biological chemistry 20020913

• Hydroxylation of indole by laboratory-evolved 2-hydroxybiphenyl 3-monooxygenase.

  The Journal of biological chemistry 20020913

• From NADH to ubiquinone in Neurospora mitochondria.

  Biochimica et biophysica acta 20020910

• Distinct patterns of mitochondrial changes precede induction of apoptosis by all-trans-retinoic acid and N-(4-hydroxyphenyl)retinamide in MCF7 breast cancer cells.

  Experimental cell research 20020910

• Human glutathione-dependent formaldehyde dehydrogenase. Structures of apo, binary, and inhibitory ternary complexes.

  Biochemistry 20020903

• Phosphite dehydrogenase: a versatile cofactor-regeneration enzyme.

  Angewandte Chemie (International ed. in English) 20020902

• Mitochondrial respiratory control can compensate for intracellular O(2) gradients in cardiomyocytes at low PO(2).

  American journal of physiology. Heart and circulatory physiology 20020901

• Comparison of the effects of ammonia on brain mitochondrial function in rats and gulf toadfish.

  American journal of physiology. Regulatory, integrative and comparative physiology 20020901

• A structurally conserved water molecule in Rossmann dinucleotide-binding domains.

  Protein science : a publication of the Protein Society 20020901

• CD38 expression and NAD+-induced intracellular Ca+ mobilization in isolated retinal Müller cells.

  Glia 20020901

• Inhibition of the mitochondrial respiratory chain by alanine in rat cerebral cortex.

  Metabolic brain disease 20020901

• Altered Ca2+ homeostasis and impaired mitochondrial function in cardiomyopathy.

  Molecular and cellular biochemistry 20020901

• Investigations of outbreaks of contagious caprine pleuropneumonia in Eritrea.

  Tropical animal health and production 20020901

• Malate dehydrogenases--structure and function.

  General physiology and biophysics 20020901

• Involvement of a plastid terminal oxidase in plastoquinone oxidation as evidenced by expression of the Arabidopsis thaliana enzyme in tobacco.

  The Journal of biological chemistry 20020830

• Rotenone-insensitive NADH dehydrogenase is a potential source of superoxide in procyclic Trypanosoma brucei mitochondria.

  Molecular and biochemical parasitology 20020828

• Biochemical and molecular characterization of the NAD(+)-dependent isocitrate dehydrogenase from the chemolithotroph Acidithiobacillus thiooxidans.

  FEMS microbiology letters 20020827

• NAD binding induces conformational changes in Rho ADP-ribosylating clostridium botulinum C3 exoenzyme.

  The Journal of biological chemistry 20020823

• Selective recovery of lactate dehydrogenase using affinity foam.

  Biotechnology and bioengineering 20020820

• Characterization of iron-sulfur protein assembly in isolated mitochondria. A requirement for ATP, NADH, and reduced iron.

  The Journal of biological chemistry 20020816

• In vitro co-metabolism of ethanol and cyclic ketones.

  Toxicology 20020815

• Significant enhancement of electron transfer reduction of NAD(+) analogues by complexation with scandium ion and the detection of the radical intermediate-scandium ion complex.

  Journal of the American Chemical Society 20020807

• Examining the relative timing of hydrogen abstraction steps during NAD(+)-dependent oxidation of secondary alcohols catalyzed by long-chain D-mannitol dehydrogenase from Pseudomonas fluorescens using pH and kinetic isotope effects.

  Biochemistry 20020806

• Is the glycolytic flux in Lactococcus lactis primarily controlled by the redox charge? Kinetics of NAD(+) and NADH pools determined in vivo by 13C NMR.

  The Journal of biological chemistry 20020802

• Kinetic regulation of the mitochondrial glycerol-3-phosphate dehydrogenase by the external NADH dehydrogenase in Saccharomyces cerevisiae.

  The Journal of biological chemistry 20020802

• Simultaneous measurements of mitochondrial NADH and Ca(2+) during increased work in intact rat heart trabeculae.

  Biophysical journal 20020801

• Prooxidant activity of free radicals derived from phenol-containing neurotransmitters.

  Toxicology 20020801

• UV filter instability: consequences for the human lens.

  Experimental eye research 20020801

• Increased glucose sensitivity of stimulus-secretion coupling in islets from Psammomys obesus after diet induction of diabetes.

  Diabetes 20020801

• Inhibition of oxidative stress produced by plasma membrane NADH oxidase delays low-potassium-induced apoptosis of cerebellar granule cells.

  Journal of neurochemistry 20020801

• NADH oxidation and NAD+ reduction catalysed by tightly coupled inside-out vesicles from Paracoccus denitrificans.

  European journal of biochemistry 20020801

• N-oxidation of aromatic amines by intracellular oxidases.

  Drug metabolism reviews 20020801

• L-aspartate oxidase is present in the anaerobic hyperthermophilic archaeon Pyrococcus horikoshii OT-3: characteristics and role in the de novo biosynthesis of nicotinamide adenine dinucleotide proposed by genome sequencing.

  Extremophiles : life under extreme conditions 20020801

• Nitric oxide induces caspase-dependent apoptosis and necrosis in neonatal rat cardiomyocytes.

  Journal of molecular and cellular cardiology 20020801

• Screening and simple purification of alanine dehydrogenase in Bacillus strains.

  Preparative biochemistry & biotechnology 20020801

• Characterization of competitive inhibitors for the transferase activity of Pseudomonas aeruginosa exotoxin A.

  Journal of enzyme inhibition and medicinal chemistry 20020801

• Regulation of cellular oncosis by uncoupling protein 2.

  The Journal of biological chemistry 20020726

• Longevity: don't hold your breath.

  Nature 20020718

• Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration.

  Nature 20020718

• Lactate -- the forgotten fuel!

  The Journal of physiology 20020715

• LC/MS analysis of NAD biosynthesis using stable isotope pyridine precursors.

  Analytical biochemistry 20020715

• Two-electron reduction of quinones by Enterobacter cloacae NAD(P)H:nitroreductase: quantitative structure-activity relationships.

  Archives of biochemistry and biophysics 20020715

• Inhibition of poly(ADP-ribose) polymerase activation attenuates beta-lapachone-induced necrotic cell death in human osteosarcoma cells.

  Toxicology and applied pharmacology 20020715

• Increased NADPH oxidase activity, gp91phox expression, and endothelium-dependent vasorelaxation during neointima formation in rabbits.

  Circulation research 20020712

• Cell biology. PARP-1--a perpetrator of apoptotic cell death?

  Science (New York, N.Y.) 20020712

• Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor.

  Science (New York, N.Y.) 20020712

• Platelet nitric oxide and superoxide release during the development of nitrate tolerance: effect of supplemental ascorbate.

  Circulation 20020709

• Ethanol cycle in an ethanologenic bacterium.

  FEBS letters 20020703

• Metabolism of the novel Ca2+-mobilizing messenger nicotinic acid-adenine dinucleotide phosphate via a 2'-specific Ca2+-dependent phosphatase.

  The Biochemical journal 20020701

• Alterations in renal mitochondrial respiration in response to the reactive oxoaldehyde methylglyoxal.

  American journal of physiology. Renal physiology 20020701

• Altered NADH and improved function by anesthetic and ischemic preconditioning in guinea pig intact hearts.

  American journal of physiology. Heart and circulatory physiology 20020701

• NH3-dependent NAD+ synthetase from Bacillus subtilis at 1 A resolution.

  Acta crystallographica. Section D, Biological crystallography 20020701

• Uptake, recycling, and antioxidant actions of alpha-lipoic acid in endothelial cells.

  Free radical biology & medicine 20020701

• Occurrence of a novel NADP(+)-linked alcohol dehydrogenase in Euglena gracilis.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020701

• Photoreactivity of aged human RPE melanosomes: a comparison with lipofuscin.

  Investigative ophthalmology & visual science 20020701

• Poly(ADP-ribose) polymerase inhibition prevents both apoptotic-like delayed neuronal death and necrosis after H(2)O(2) injury.

  Journal of neurochemistry 20020701

• Peroxidase activity develops in the micropylar endosperm of tomato seeds prior to radicle protrusion.

  Journal of experimental botany 20020701

• The importance of cycling of blood alcohol levels in the pathogenesis of experimental alcoholic liver disease in rats.

  Gastroenterology 20020701

• Effect of glucose on glycerol bioconversion by Lactobacillus reuteri.

  Applied microbiology and biotechnology 20020701

• Morphology of the cricopharyngeal muscle in Zenker and control specimens.

  The Annals of otology, rhinology, and laryngology 20020701

• The unorthodox histidine kinases BvgS and EvgS are responsive to the oxidation status of a quinone electron carrier.

  European journal of biochemistry 20020701

• Tricarboxylic acid cycle substrates prevent PARP-mediated death of neurons and astrocytes.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020701

• Synchrotron infrared spectromicroscopy as a novel bioanalytical microprobe for individual living cells: cytotoxicity considerations.

  Journal of biomedical optics 20020701

• Peroxo-bridged divanadate as selective bromide oxidant in bromoperoxidation.

  Molecular and cellular biochemistry 20020701

• Growth-promoting activity of pyrazinoic acid, a putative active compound of antituberculosis drug pyrazinamide, in niacin-deficient rats through the inhibition of ACMSD activity.

  Bioscience, biotechnology, and biochemistry 20020701

• [Role of NADH shuttle system in glucose-stimulated insulin secretion].

  Nihon rinsho. Japanese journal of clinical medicine 20020701

• Metabolic engineering of Escherichia coli: increase of NADH availability by overexpressing an NAD(+)-dependent formate dehydrogenase.

  Metabolic engineering 20020701

• The effect of increasing NADH availability on the redistribution of metabolic fluxes in Escherichia coli chemostat cultures.

  Metabolic engineering 20020701

• The effect of NAPRTase overexpression on the total levels of NAD, the NADH/NAD+ ratio, and the distribution of metabolites in Escherichia coli.

  Metabolic engineering 20020701

• Catalytic mechanism of S-adenosylhomocysteine hydrolase. Site-directed mutagenesis of Asp-130, Lys-185, Asp-189, and Asn-190.

  The Journal of biological chemistry 20020621

• Isocitrate binding at two functionally distinct sites in yeast NAD+-specific isocitrate dehydrogenase.

  The Journal of biological chemistry 20020621

• Crystal structure of a biliverdin IXalpha reductase enzyme-cofactor complex.

  Journal of molecular biology 20020621

• The inhibition of poly(ADP-ribose) polymerase enhances growth rates of ataxia telangiectasia cells.

  Archives of biochemistry and biophysics 20020615

• Mitochondrial superoxide production during oxalate-mediated oxidative stress in renal epithelial cells.

  Free radical biology & medicine 20020615

• Integration of polyaniline/poly(acrylic acid) films and redox enzymes on electrode supports: an in situ electrochemical/surface plasmon resonance study of the bioelectrocatalyzed oxidation of glucose or lactate in the integrated bioelectrocatalytic systems.

  Journal of the American Chemical Society 20020605

• Multiple conformations of NAD and NADH when bound to human cytosolic and mitochondrial aldehyde dehydrogenase.

  Biochemistry 20020604

• Mitochondrial dysfunction is an early event in high-NaCl-induced apoptosis of mIMCD3 cells.

  American journal of physiology. Renal physiology 20020601

• A high-throughput screening microplate test for the interaction of drugs with P-glycoprotein.

  Analytical biochemistry 20020601

• A resorufin-based fluorescent assay for quantifying NADH.

  Analytical biochemistry 20020601

• Homology modeling and molecular dynamics study of NAD-dependent glycerol-3-phosphate dehydrogenase from Trypanosoma brucei rhodesiense, a potential target enzyme for anti-sleeping sickness drug development.

  Biophysical journal 20020601

• Unusual enzymatic hydrolysis of NAD by solubilized form of NAD(+) glycohydrolase.

  Chemical & pharmaceutical bulletin 20020601

• Variation on a theme of SDR. dTDP-6-deoxy-L- lyxo-4-hexulose reductase (RmlD) shows a new Mg2+-dependent dimerization mode.

  Structure (London, England : 1993) 20020601

• Altered arachidonic acid biosynthesis and antioxidant protection mechanisms in Schwann cells grown in elevated glucose.

  Journal of neurochemistry 20020601

• Kinetics of the transhydrogenase reaction catalyzed by mitochondrial NADH:ubiquinone oxidoreductase (complex I).

  Biochemistry. Biokhimiia 20020601

• Effects of fatty liver induced by niacin-free diet with orotic acid on the metabolism of tryptophan to niacin in rats.

  Bioscience, biotechnology, and biochemistry 20020601

• Substrate specificity of mammalian pyridine nucleotide transglycosidases.

  Journal of nutritional science and vitaminology 20020601

• Synthesis of pyridine nucleotide analogs consisting of nicotinoylamino acids by means of transglycosidation reactions catalyzed by mammalian pyridine nucleotide transglycosidases.

  Journal of nutritional science and vitaminology 20020601

• A bacterial flavin reductase system reduces chromate to a soluble chromium(III)-NAD(+) complex.

  Biochemical and biophysical research communications 20020531

• Structural identification of 2'- and 3'-O-acetyl-ADP-ribose as novel metabolites derived from the Sir2 family of beta -NAD+-dependent histone/protein deacetylases.

  The Journal of biological chemistry 20020524

• Optimizing an artificial metabolic pathway: engineering the cofactor specificity of Corynebacterium 2,5-diketo-D-gluconic acid reductase for use in vitamin C biosynthesis.

  Biochemistry 20020521

• A phosphate-stimulated NAD(P)+-dependent glyceraldehyde-3-phosphate dehydrogenase in Bacillus cereus.

  FEMS microbiology letters 20020521

• Glutamate dehydrogenase of Halobacterium salinarum: evidence that the gene sequence currently assigned to the NADP+-dependent enzyme is in fact that of the NAD+-dependent glutamate dehydrogenase.

  FEMS microbiology letters 20020521

• Purification and characterization of ferredoxin-NAD(P)(+) reductase from the green sulfur bacterium Chlorobium tepidum.

  Biochimica et biophysica acta 20020520

• A novel water-soluble Hantzsch 1,4-dihydropyridine compound that functions in biological processes through NADH regeneration.

  The Journal of organic chemistry 20020517

• Cardiolipin prevents rate-dependent uncoupling and provides osmotic stability in yeast mitochondria.

  The Biochemical journal 20020515

• Mediator-modified electrodes for catalytic NADH oxidation: high rate constants at interesting overpotentials.

  Bioelectrochemistry (Amsterdam, Netherlands) 20020515

• VDAC channels differentiate between natural metabolites and synthetic molecules.

  The Journal of membrane biology 20020515

• Purification and characterization of a doxorubicin-inhibited NADH-quinone (NADH-ferricyanide) reductase from rat liver plasma membranes.

  The Journal of biological chemistry 20020510

• Fluorinated NAD as an affinity surfactant.

  Chemical communications (Cambridge, England) 20020507

• Liposomal NAD(+) prevents diminished O(2) consumption by immunostimulated Caco-2 cells.

  American journal of physiology. Lung cellular and molecular physiology 20020501

• Two-photon fluorescence spectroscopy and microscopy of NAD(P)H and flavoprotein.

  Biophysical journal 20020501

• Mitochondrial oxidative stress and CD95 ligand: a dual mechanism for hepatocyte apoptosis in chronic alcoholism.

  Hepatology (Baltimore, Md.) 20020501

• Chiral alcohol production by NADH-dependent phenylacetaldehyde reductase coupled with in situ regeneration of NADH.

  European journal of biochemistry 20020501

• Oxidation of 5'-site guanine at GG and GGG sequences induced by a metabolite of carcinogenic heterocyclic amine PhIP in the presence of Cu(II) and NADH.

  Carcinogenesis 20020501

• Implication by site-directed mutagenesis of Arg314 and Tyr316 in the coenzyme site of pig mitochondrial NADP-dependent isocitrate dehydrogenase.

  Archives of biochemistry and biophysics 20020501

• Dinitrophenol pretreatment of rat ventricular myocytes protects against damage by metabolic inhibition and reperfusion.

  Journal of molecular and cellular cardiology 20020501

• Inhibition by wine polyphenols of peroxynitrite-initiated chemiluminescence and NADH oxidation.

  Annals of the New York Academy of Sciences 20020501

• Polyphenols in red wines prevent NADH oxidation induced by peroxynitrite.

  Annals of the New York Academy of Sciences 20020501

• Thyroid hormone-induced protein (TIP) gene expression by 3,5,3(')-triiodothyronine in the ovarian follicle of perch (Anabas testudineus, Bloch): modulation of 3beta-hydroxysteroid dehydrogenase/Delta(5)-Delta(4)-isomerase enzyme by TIP.

  General and comparative endocrinology 20020501

• 2,4,6-trinitrotoluene-induced reproductive toxicity via oxidative DNA damage by its metabolite.

  Free radical research 20020501

• X-ray crystal structure of benzoate 1,2-dioxygenase reductase from Acinetobacter sp. strain ADP1.

  Journal of molecular biology 20020426

• Crystal structure of the alcohol dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus at 1.85 A resolution.

  Journal of molecular biology 20020426

• Aerobic and anaerobic NAD+ metabolism in Saccharomyces cerevisiae.

  FEBS letters 20020424

• Identification of residues important for NAD+ binding by the Thermotoga maritima alpha-glucosidase AglA, a member of glycoside hydrolase family 4.

  FEBS letters 20020424

• Productive trapping of NAD-type radicals. Non-biomimetic reduction of pyridinium salts.

  Chemical communications (Cambridge, England) 20020421

• Furfural, 5-hydroxymethyl furfural, and acetoin act as external electron acceptors during anaerobic fermentation of xylose in recombinant Saccharomyces cerevisiae.

  Biotechnology and bioengineering 20020420

• Formation of peroxynitrite from reaction of nitroxyl anion with molecular oxygen.

  The Journal of biological chemistry 20020419

• Elucidation of the metabolic fate of glucose in the filamentous fungus Trichoderma reesei using expressed sequence tag (EST) analysis and cDNA microarrays.

  The Journal of biological chemistry 20020419

• Domain closure, substrate specificity and catalysis of D-lactate dehydrogenase from Lactobacillus bulgaricus.

  Journal of molecular biology 20020419

• Alteration of inhibitor selectivity by site-directed mutagenesis of Arg(294) in the ADP-glucose pyrophosphorylase from Anabaena PCC 7120.

  Archives of biochemistry and biophysics 20020415

• Reduced nicotinamide nucleotides prevent nitration of tyrosine hydroxylase by peroxynitrite.

  Brain research 20020412

• Reactive oxygen species inhibit the succinate oxidation-supported generation of membrane potential in wheat mitochondria.

  FEBS letters 20020410

• First purification of the antiquitin protein and demonstration of its enzymatic activity.

  FEBS letters 20020410

• Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues.

  The Journal of biological chemistry 20020405

• Modulation by substrates of the protective effect of cyclosporin A on mitochondrial damage.

  Life sciences 20020405

• Identification of a protein-promoting vibration in the reaction catalyzed by horse liver alcohol dehydrogenase.

  Journal of the American Chemical Society 20020403

• NADH interactions with WT- and S94A-acyl carrier protein reductase from Mycobacterium tuberculosis: an ab initio study.

  Proteins 20020401

• Influence of mycophenolic acid on inosine 5'-monophosphate dehydrogenase activity in human peripheral blood mononuclear cells.

  Clinica chimica acta; international journal of clinical chemistry 20020401

• Evidence that hydroxyl radicals mediate auxin-induced extension growth.

  Planta 20020401

• The chemistry of nicotinamide adenine dinucleotide (NAD) analogues containing C-nucleosides related to nicotinamide riboside.

  Current medicinal chemistry 20020401

• Lactate dehydrogenase-C4 is involved in heparin- and NADH-dependent bovine sperm capacitation.

  Andrologia 20020401

• The roles of the polytopic membrane proteins NarK, NarU and NirC in Escherichia coli K-12: two nitrate and three nitrite transporters.

  Molecular microbiology 20020401

• Glycyrrhizic acid suppresses type 2 11 beta-hydroxysteroid dehydrogenase expression in vivo.

  The Journal of steroid biochemistry and molecular biology 20020401

• Effect of coenzymes and thyroid hormones on the dual activities of Xenopus cytosolic thyroid-hormone-binding protein (xCTBP) with aldehyde dehydrogenase activity.

  European journal of biochemistry 20020401

• Metabolic engineering through cofactor manipulation and its effects on metabolic flux redistribution in Escherichia coli.

  Metabolic engineering 20020401

• [Electron transfer flavoprotein in mitochondria].

  Nihon rinsho. Japanese journal of clinical medicine 20020401

• Enzymes of malate metabolism in Mesorhizobium ciceri CC 1192.

  Canadian journal of microbiology 20020401

• Elucidation of the toxic mechanism of the plasticizers, phthalic acid esters, putative endocrine disrupters: effects of dietary di(2-ethylhexyl)phthalate on the metabolism of tryptophan to niacin in rats.

  Bioscience, biotechnology, and biochemistry 20020401

• NADH oxidation by manganese peroxidase with or without alpha-hydroxy acid.

  Bioscience, biotechnology, and biochemistry 20020401

• Biosynthesis of vitamin B6 in Rhizobium: in vitro synthesis of pyridoxine from 1-deoxy-D-xylulose and 4-hydroxy-L-threonine.

  Bioscience, biotechnology, and biochemistry 20020401

• The flavo-enzyme xanthine oxidase is under circadian control in the marine alga Gonyaulax.

  Die Naturwissenschaften 20020401

• Coenzyme Q cytoprotective mechanisms for mitochondrial complex I cytopathies involves NAD(P)H: quinone oxidoreductase 1(NQO1).

  Free radical research 20020401

• Glutathione and NADH, but not ascorbate, protect lens proteins from modification by UV filters.

  Experimental eye research 20020401

• Bioavailability of reduced nicotinamide-adenine-dinucleotide (NADH) in the central nervous system of the anaesthetized rat measured by laser-induced fluorescence spectroscopy.

  Pharmacology & toxicology 20020401

• NAD-dependent inhibition of the NAD-glycohydrolase activity in A549 cells.

  Molecular and cellular biochemistry 20020401

• Medicinal chemistry of nicotinamide in the treatment of ischemia and reperfusion.

  Mini reviews in medicinal chemistry 20020401

• Zinc is a potent inhibitor of thiol oxidoreductase activity and stimulates reactive oxygen species production by lipoamide dehydrogenase.

  The Journal of biological chemistry 20020322

• Conserved residues in domain Ia are required for the reaction of Escherichia coli DNA ligase with NAD+.

  The Journal of biological chemistry 20020322

• Mutation in the glucose-6-phosphate dehydrogenase gene leads to inactivation of Ku DNA end binding during oxidative stress.

  The Journal of biological chemistry 20020322

• Mechanism of peroxidase-mediated oxidation of carcinogenic o-anisidine and its binding to DNA.

  Mutation research 20020320

• The crystal structure and mechanism of 1-L-myo-inositol- 1-phosphate synthase.

  The Journal of biological chemistry 20020315

• Structure of human NMN adenylyltransferase. A key nuclear enzyme for NAD homeostasis.

  The Journal of biological chemistry 20020308

• Regulation of corepressor function by nuclear NADH.

  Science (New York, N.Y.) 20020308

• Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling.

  Circulation research 20020308

• Cytotoxic mechanism of Vibrio vulnificus cytolysin in CPAE cells.

  Life sciences 20020308

• Control of oxygen free radical formation from mitochondrial complex I: roles for protein kinase A and pyruvate dehydrogenase kinase.

  Free radical biology & medicine 20020301

• Overestimation of NADH-driven vascular oxidase activity due to lucigenin artifacts.

  Free radical biology & medicine 20020301

• The Antarctic Psychrobacter sp. TAD1 has two cold-active glutamate dehydrogenases with different cofactor specificities. Characterisation of the NAD+-dependent enzyme.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20020301

• A novel mechanism for coupling cellular intermediary metabolism to cytosolic Ca2+ signaling via CD38/ADP-ribosyl cyclase, a putative intracellular NAD+ sensor.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020301

• Red blood cell antioxidant and iron status in alcoholic and nonalcoholic cirrhosis.

  European journal of clinical investigation 20020301

• Histochemical evidence for pathways insulin cells use to oxidize glycolysis-derived NADH.

  Metabolism: clinical and experimental 20020301

• 1,3-Dinitrobenzene metabolism and protein binding.

  Chemical research in toxicology 20020301

• Telomeric and rDNA silencing in Saccharomyces cerevisiae are dependent on a nuclear NAD(+) salvage pathway.

  Genetics 20020301

• A low-resolution 3D model of the tetrameric alcohol dehydrogenase from Sulfolobus solfataricus.

  Protein engineering 20020301

• Interactions in solution of cobalt(II) and nickel(II) with nicotinamide adenine dinucleotide: a potentiometric and calorimetric study.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20020301

• Insulin increases NADH/NAD+ redox state, which stimulates guanylate cyclase in vascular smooth muscle.

  American journal of hypertension 20020301

• Purification and characterization of pyridoxal 4-dehydrogenase from Aureobacterium luteolum.

  Bioscience, biotechnology, and biochemistry 20020301

• Crystal structure of inositol 1-phosphate synthase from Mycobacterium tuberculosis, a key enzyme in phosphatidylinositol synthesis.

  Structure (London, England : 1993) 20020301

• The use of cyclic voltammetric measurements for the determination of kinetic constants in enzyme-based electrocatalysis. The case of the redox mediated dihydronicotinamide adenine dinucleotide oxidation catalyzed by flavoproteins.

  Annali di chimica 20020301

• [Effect of NADH against liver cell line L02 apoptosis induced by UVB irradiation].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20020301

• Reactivity of the B-H Bond in tris(pyrazolyl)hydroborato zinc complexes: unexpected example of zinc hydride formation in a protic solvent and its relevance towards hydrogen transfer to NAD(+) mimics by tris(pyrazolyl)hydroborato zinc complexes in alcoholic media.

  Inorganic chemistry 20020225

• Crystallographic studies on human BST-1/CD157 with ADP-ribosyl cyclase and NAD glycohydrolase activities.

  Journal of molecular biology 20020222

• Redox control of the P450cam catalytic cycle: effects of Y96F active site mutation and binding of a non-natural substrate.

  Chemical communications (Cambridge, England) 20020221

• Biphasic oxidation of mitochondrial NAD(P)H.

  Biochemical and biophysical research communications 20020215

• Correlation of NADH and Ca2+ signals in mouse pancreatic acinar cells.

  The Journal of physiology 20020215

• WK175, a novel antitumor agent, decreases the intracellular nicotinamide adenine dinucleotide concentration and induces the apoptotic cascade in human leukemia cells.

  Cancer research 20020215

• Control of oxidative phosphorylation by Complex I in rat liver mitochondria: implications for aging.

  Biochimica et biophysica acta 20020215

• An NADH-dependent bacterial thioredoxin reductase-like protein in conjunction with a glutaredoxin homologue form a unique peroxiredoxin (AhpC) reducing system in Clostridium pasteurianum.

  Biochemistry 20020212

• The 11 beta-hydroxysteroid dehydrogenase type 2 activity in human placental microsomes is inactivated by zinc and the sulfhydryl modifying reagent N-ethylmaleimide.

  Biochimica et biophysica acta 20020211

• Entrainment in solution of an oscillating NADH oxidase activity from the bovine milk fat globule membrane with a temperature-compensated period length suggestive of an ultradian time-keeping (clock) function.

  Biochimica et biophysica acta 20020210

• Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein.

  Science (New York, N.Y.) 20020208

• Enhanced activity of the plasma membrane oxidoreductase in circulating lymphocytes from insulin-dependent diabetes mellitus patients.

  Biochemical and biophysical research communications 20020208

• Substituted aniline interaction with submitochondrial particles and quantitative structure-activity relationships.

  Biochimica et biophysica acta 20020201

• Effects of NADH and NADPH on superoxide levels and cerebral vascular tone.

  American journal of physiology. Heart and circulatory physiology 20020201

• In situ staining of activities of enzymes involved in carbohydrate metabolism in plant tissues.

  Journal of experimental botany 20020201

• Evidence that a type-2 NADH:quinone oxidoreductase mediates electron transfer to particulate methane monooxygenase in methylococcus capsulatus.

  Archives of biochemistry and biophysics 20020201

• Identification and functional analysis of the Saccharomyces cerevisiae nicotinamidase gene, PNC1.

  Yeast (Chichester, England) 20020201

• Nitric oxide-mediated chondrocyte cell death requires the generation of additional reactive oxygen species.

  Arthritis and rheumatism 20020201

• Kinetic study of sn-glycerol-1-phosphate dehydrogenase from the aerobic hyperthermophilic archaeon, Aeropyrum pernix K1.

  European journal of biochemistry 20020201

• Modulation of apoptosis by mitochondrial uncouplers: apoptosis-delaying features despite intrinsic cytotoxicity.

  Biochemical pharmacology 20020201

• Steady-state kinetics of NADH:coenzyme Q oxidoreductase isolated from bovine heart mitochondria.

  Journal of bioenergetics and biomembranes 20020201

• Interactions between the cytochrome pathway and the alternative oxidase in isolated Acanthamoeba castellanii mitochondria.

  Journal of bioenergetics and biomembranes 20020201

• The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.

  Cancer chemotherapy and pharmacology 20020201

• The ARTT motif and a unified structural understanding of substrate recognition in ADP-ribosylating bacterial toxins and eukaryotic ADP-ribosyltransferases.

  International journal of medical microbiology : IJMM 20020201

• Isotope effects and intermediates in the reduction of NO by P450(NOR).

  Journal of inorganic biochemistry 20020201

• Alteration of the specificity of the cofactor-binding pocket of Corynebacterium 2,5-diketo-D-gluconic acid reductase A.

  Protein engineering 20020201

• Isolation and characterization of tightly coupled mitochondria from wild type and nap mutant Neurospora crassa.

  Biochemistry. Biokhimiia 20020201

• Mechanistic model of myocardial energy metabolism under normal and ischemic conditions.

  Annals of biomedical engineering 20020201

• Chemical modification of specific active site amino acid residues of Enterobacter aerogenes glycerol dehydrogenase.

  Journal of enzyme inhibition and medicinal chemistry 20020201

• Biomimetic NAD(+) models for tandem cofactor regeneration, horse liver alcohol dehydrogenase recognition of 1,4-NADH derivatives, and chiral synthesis.

  Angewandte Chemie (International ed. in English) 20020201

• A mutational analysis of the active site of human type II inosine 5'-monophosphate dehydrogenase.

  Biochimica et biophysica acta 20020131

• A site-directed mutagenesis analysis of tNOX functional domains.

  Biochimica et biophysica acta 20020131

• Oxidative decarboxylation of UDP-glucuronic acid in extracts of polymyxin-resistant Escherichia coli. Origin of lipid a species modified with 4-amino-4-deoxy-L-arabinose.

  The Journal of biological chemistry 20020125

• Double base lesions of DNA by a metabolite of carcinogenic benzo[a]pyrene.

  Biochemical and biophysical research communications 20020118

• Roles of DNA fragmentation factor and poly(ADP-ribose) polymerase-1 in sensitization of fibroblasts to tumor necrosis factor-induced apoptosis.

  Biochemical and biophysical research communications 20020118

• A novel cycling assay for cellular cADP-ribose with nanomolar sensitivity.

  The Biochemical journal 20020115

• Paraquat-induced oxidative stress and dysfunction of the glutathione redox cycle in pulmonary microvascular endothelial cells.

  Toxicology and applied pharmacology 20020115

• Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury.

  Biochemical pharmacology 20020115

• Structure of the plant alternative oxidase. Site-directed mutagenesis provides new information on the active site and membrane topology.

  The Journal of biological chemistry 20020111

• Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient mice.

  The Journal of biological chemistry 20020104

• Metabolic consequence of long-term exposure of pancreatic beta cells to free fatty acid with special reference to glucose insensitivity.

  Biochimica et biophysica acta 20020102

• An aldose reductase inhibitor reverses early diabetes-induced changes in peripheral nerve function, metabolism, and antioxidative defense.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020101

• Intracellular redox status affects transplasma membrane electron transport in pulmonary arterial endothelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20020101

• Identification of tissue transglutaminase-reactive lysine residues in glyceraldehyde-3-phosphate dehydrogenase.

  Protein science : a publication of the Protein Society 20020101

• Detection of poly(ADP-ribose) polymerase activation in oxidatively stressed cells and tissues using biotinylated NAD substrate.

  The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20020101

• Dynamics of nucleotides in VDAC channels: structure-specific noise generation.

  Biophysical journal 20020101

• Reactive oxygen species alter gene expression in podocytes: induction of granulocyte macrophage-colony-stimulating factor.

  Journal of the American Society of Nephrology : JASN 20020101

• Inducible protective processes in animal systems. X. Influence of nicotinamide in methyl methanesulfonate-adapted mouse bone marrow cells.

  Mutagenesis 20020101

• Pharmacological intakes of niacin increase bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats.

  The Journal of nutrition 20020101

• Immobilisation of enzymes on poly(aniline)-poly(anion) composite films. Preparation of bioanodes for biofuel cell applications.

  Bioelectrochemistry (Amsterdam, Netherlands) 20020101

• Crystal structures of E. coli nicotinate mononucleotide adenylyltransferase and its complex with deamido-NAD.

  Structure (London, England : 1993) 20020101

• LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death.

  Molecular cell 20020101

• Inhibition of 11beta-hydroxysteroid dehydrogenase in guinea pig kidney by three bioflavonoids and their interactions with gossypol.

  Acta pharmacologica Sinica 20020101

• A role for MAP kinase in the antitumor activity of a nucleoside analog.

  Cancer gene therapy 20020101

• On-column enzyme-catalyzed microreactions using capillary electrophoresis: quantitative studies.

  Journal of capillary electrophoresis and microchip technology 20020101

• Enzymatic amplification by substrate recycling for alpha-ketoglutarate in conjunction with capillary electrophoresis.

  Journal of capillary electrophoresis and microchip technology 20020101

• Minimal promoter for the NAD+-specific glutamate dehydrogenase gene of Neurospora crassa.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20020101

• The role of poly-hydroxy-alkanoate form in determining the response of enhanced biological phosphorus removal biomass to volatile fatty acids.

  Water environment research : a research publication of the Water Environment Federation 20020101

• Utilization of xylitol dehydrogenase in a combined microbial/enzymatic process for production of xylitol from D-glucose.

  Applied biochemistry and biotechnology 20020101

• Cell enlargement of plant tissue explants oscillates with a temperature-compensated period of ca. 24 min.

  In vitro cellular & developmental biology. Plant : journal of the Tissue Culture Association 20020101

• Molecular cloning and tissue distribution of mammalian L-threonine 3-dehydrogenases.

  BMC biochemistry 20020101

• Visible light induced biohydrogen production from sucrose using the photosensitization of Mg chlorophyll-a.

  Bioconjugate chemistry 20020101

• Functional imaging of mitochondrial redox state.

  Methods in enzymology 20020101

• Three-dimensional redox imaging of frozen-quenched brain and other organs.

  Methods in enzymology 20020101

• Cell death and metabolic activity during epileptiform discharges and status epilepticus in the hippocampus.

  Progress in brain research 20020101

• Threonine 11 of human NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase may interact with NAD(+) during catalysis.

  Prostaglandins, leukotrienes, and essential fatty acids 20020101

• Pyridine nucleotide redox potential in erythrocytes of saudi subjects with sickle cell disease.

  Acta haematologica 20020101

• Studies on the cardiotoxicity of noradrenaline in isolated rabbit hearts.

  Arzneimittel-Forschung 20020101

• [Intermittent hypoxic training and L-arginine as corrective agents for myocardial energy supply under acute hypoxia].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20020101

• Impaired hypoxic tolerance and altered protein binding of NADH in presymptomatic APP23 transgenic mice.

  Neuroscience 20020101

• Time dependent responses of glycolytic intermediates in a detailed glycolytic model of Lactococcus lactis during glucose run-out experiments.

  Molecular biology reports 20020101

• [Effect of nicotinamide adenine dinucleotide on the serotoninergic mediator system in the rat brain during 3-acetylpyridine administration].

  Voprosy meditsinskoi khimii 20020101

• Streptozotocin upregulates GAD67 expression in MIN6N8a mouse beta cells.

  Journal of autoimmunity 20020101

• [Stabilized NADH (ENADA) improves jet lag-induced cognitive performance deficit].

  Wiener medizinische Wochenschrift (1946) 20020101

• Desferrioxamine decreases NAD redox potential of intact red blood cells: evidence for desferrioxamine as an inducer of oxidant stress in red blood cells.

  BMC clinical pharmacology 20020101

• Sensitizer-linked substrates and ligands: ruthenium probes of cytochrome P450 structure and mechanism.

  Methods in enzymology 20020101

• NAD+ catabolism in pheochromocytoma rat cells.

  Journal of biological regulators and homeostatic agents 20020101

• Role of dihydrolipoyl dehydrogenase (E3) and a novel E3-binding protein in the NADH sensitivity of the pyruvate dehydrogenase complex from anaerobic mitochondria of the parasitic nematode, Ascaris suum.

  Molecular and biochemical parasitology 20020101

• Interference-free biosensor based on screen-printing technology and sol-gel immobilization for determination of acetaldehyde in wine.

  Journal of AOAC International 20020101

• Melatonin inhibits the contractile effect of vanadate in the isolated pulmonary arterial rings of rats: possible role of hydrogen peroxide.

  Journal of biochemical and molecular toxicology 20020101

• X-linked myotubular myopathy with probable germline mosaicism.

  Clinical neuropathology 20020101

• Bench-to-bedside review: Cytopathic hypoxia.

  Critical care (London, England) 20020101

• Kinetic and molecular modeling of nucleoside and nucleotide inhibition of malate dehydrogenase.

  Nucleosides, nucleotides & nucleic acids 20020101

• Development of a high-throughput screening-amenable assay for human poly(ADP-ribose) polymerase inhibitors.

  Journal of pharmacological and toxicological methods 20020101

• Reduction of 8a-hydroxy-2,2,5,7,8-pentamethyl-6-chromanone.

  Redox report : communications in free radical research 20020101

• Structure-based experimental confirmation of biochemical function to a methyltransferase, MJ0882, from hyperthermophile Methanococcus jannaschii.

  Journal of structural and functional genomics 20020101

• Structural analysis of Saccharomyces cerevisiae myo-inositol phosphate synthase.

  Journal of structural and functional genomics 20020101

• Reduction of mercuric ion in vitro by superoxide anion.

  Physiological chemistry and physics and medical NMR 20020101

• Chemistry of gene silencing: the mechanism of NAD+-dependent deacetylation reactions.

  Biochemistry 20011225

• Identification of a small molecule inhibitor of Sir2p.

  Proceedings of the National Academy of Sciences of the United States of America 20011218

• Bioorganometallic chemistry. 13. Regioselective reduction of NAD(+) models, 1-benzylnicotinamde triflate and beta-nicotinamide ribose-5'-methyl phosphate, with in situ generated [CpRh(Bpy)H](+): structure-activity relationships, kinetics, and mechanistic aspects in the formation of the 1,4-NADH derivatives.

  Inorganic chemistry 20011217

• Assay for ADP-ribosyl cyclase by reverse-phase high-performance liquid chromatography.

  Analytical biochemistry 20011215

• Kinetic determinants of the interaction of enoyl-ACP reductase from Plasmodium falciparum with its substrates and inhibitors.

  Biochemical and biophysical research communications 20011214

• Recognition templates for predicting adenylate-binding sites in proteins.

  Journal of molecular biology 20011214

• Dynamic structures of horse liver alcohol dehydrogenase (HLADH): results of molecular dynamics simulations of HLADH-NAD(+)-PhCH(2)OH, HLADH-NAD(+)-PhCH(2)O(-), and HLADH-NADH-PhCHO.

  Journal of the American Chemical Society 20011205

• Diphtheria toxin catalyzed hydrolysis of NAD(+): molecular dynamics study of enzyme-bound substrate, transition state, and inhibitor.

  Journal of the American Chemical Society 20011205

• Functional evaluation of serine/threonine residues in the P-Loop of Rhodobacter sphaeroides phosphoribulokinase.

  Biochemistry 20011204

• The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases.

  The EMBO journal 20011203

• A fast and efficient metal-mediated oxidation of isoniazid and identification of isoniazid-NAD(H) adducts.

  Chembiochem : a European journal of chemical biology 20011203

• Electrodes modified with nitrofluorenone derivatives as a basis for new biosensors.

  Biosensors & bioelectronics 20011201

• Determination of the mechanism of human malic enzyme with natural and alternate dinucleotides by isotope effects.

  Archives of biochemistry and biophysics 20011201

• Kinetic locking-on strategy and auxiliary tactics for bioaffinity purification of NAD(P)(+)-dependent dehydrogenases.

  Analytical biochemistry 20011201

• 3Beta-brassinosteroid dehydrogenase activity in Arabidopsis and tomato.

  Phytochemistry 20011201

• Glutamate-loading stimulates metabolic flux and improves cell recovery following chemical hypoxia in isolated cardiomyocytes.

  Journal of molecular and cellular cardiology 20011201

• Regulation of sodium-calcium exchange and mitochondrial energetics by Bcl-2 in the heart of transgenic mice.

  Journal of molecular and cellular cardiology 20011201

• AI-based algorithms for protein surface comparisons.

  Computers & chemistry 20011201

• Activities of enzymes in the malate-aspartate shuttle in the peripheral leukocytes of dogs and cats.

  Veterinary research communications 20011201

• Characterization of pyridine nucleotide coenzymes in the hyperthermophilic archaeon Pyrococcus furiosus.

  Extremophiles : life under extreme conditions 20011201

• In vivo NADH fluorescence monitoring as an assay for cellular damage in photodynamic therapy.

  Photochemistry and photobiology 20011201

• Human aldehyde dehydrogenase catalytic activity and structural interactions with coenzyme analogs.

  Journal of biomolecular structure & dynamics 20011201

• Deoxypodophyllotoxin 6-hydroxylase, a cytochrome P450 monooxygenase from cell cultures of Linum flavum involved in the biosynthesis of cytotoxic lignans.

  Planta 20011201

• Cold acclimation of Arabidopsis thaliana results in incomplete recovery of photosynthetic capacity, associated with an increased reduction of the chloroplast stroma.

  Planta 20011201

• Rapid reversion of aging phenotypes by nicotinamide through possible modulation of histone acetylation.

  Cellular and molecular life sciences : CMLS 20011201

• Determination of NADH in frozen rat brain sections by laser-induced fluorescence.

  Biological chemistry 20011201

• Purification and enzymatic activity of an NADH-fumarate reductase and other mitochondrial activities of Leishmania parasites.

  APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20011201

• The determination of ketone bodies: preanalytical, analytical and physiological considerations.

  Clinical and experimental medicine 20011201

• UDP-galactose 4-epimerase from Escherichia coli: equilibrium unfolding studies.

  Indian journal of biochemistry & biophysics 20011201

• Fast hydride transfer in proton-translocating transhydrogenase revealed in a rapid mixing continuous flow device.

  The Journal of biological chemistry 20011130

• Peroxidase activity of in vitro-selected 2'-amino RNAs.

  Biotechnology and bioengineering 20011120

• Respiratory chain network in mitochondria of Candida parapsilosis: ADP/O appraisal of the multiple electron pathways.

  FEBS letters 20011116

• Hydride transfer in liver alcohol dehydrogenase: quantum dynamics, kinetic isotope effects, and role of enzyme motion.

  Journal of the American Chemical Society 20011114

• The structure and biochemistry of NADH-dependent cytochrome b5 reductase are now consistent.

  Biochemistry 20011113

• NADH dehydrogenase of Corynebacterium glutamicum. Purification of an NADH dehydrogenase II homolog able to oxidize NADPH.

  FEMS microbiology letters 20011113

• Comparative analysis of folding and substrate binding sites between regulated hexameric type II citrate synthases and unregulated dimeric type I enzymes.

  Biochemistry 20011106

• The 'open' and 'closed' structures of the type-C inorganic pyrophosphatases from Bacillus subtilis and Streptococcus gordonii.

  Journal of molecular biology 20011102

• Chemical synthesis of 16beta-propylaminoacyl derivatives of estradiol and their inhibitory potency on type 1 17beta-hydroxysteroid dehydrogenase and binding affinity on steroid receptors.

  Steroids 20011101

• Critical residues for the specificity of cofactors and substrates in human estrogenic 17beta-hydroxysteroid dehydrogenase 1: variants designed from the three-dimensional structure of the enzyme.

  Molecular endocrinology (Baltimore, Md.) 20011101

• NAD degradation and regulation of CD38 expression by human monocytes/macrophages.

  European journal of biochemistry 20011101

• Octyl glucoside induced formation of the molten globule-like state of glutamate dehydrogenase.

  Journal of biochemistry 20011101

• Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo.

  Nature medicine 20011101

• Abscisic acid activation of plasma membrane Ca(2+) channels in guard cells requires cytosolic NAD(P)H and is differentially disrupted upstream and downstream of reactive oxygen species production in abi1-1 and abi2-1 protein phosphatase 2C mutants.

  The Plant cell 20011101

• Metabolism of tirapazamine by multiple reductases in the nucleus.

  Biochemical pharmacology 20011101

• Hydroxyurea induces site-specific DNA damage via formation of hydrogen peroxide and nitric oxide.

  Japanese journal of cancer research : Gann 20011101

• NADH/NADPH oxidase p22 phox C242T polymorphism and lipid peroxidation in coronary artery disease.

  Clinical physiology (Oxford, England) 20011101

• Determination of D-sorbitol in human erythrocytes by an enzymatic fluorometric method with an improved deproteinization procedure.

  Annals of clinical biochemistry 20011101

• Contribution of engineered electrostatic interactions to the stability of cytosolic malate dehydrogenase.

  Protein engineering 20011101

• Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymerase.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20011101

• Changes of pyridine nucleotide levels during adipocyte differentiation of mouse 3T3-L1 cells.

  Bioscience, biotechnology, and biochemistry 20011101

• Self-powered enzyme-based biosensors.

  Journal of the American Chemical Society 20011031

• Metal ion-catalyzed cycloaddition vs hydride transfer reactions of NADH analogues with p-benzoquinones.

  Journal of the American Chemical Society 20011024

• Contributions of valine-292 in the nicotinamide binding site of liver alcohol dehydrogenase and dynamics to catalysis.

  Biochemistry 20011023

• Enhanced acid stability of a reduced nicotinamide adenine dinucleotide (NADH) analogue.

  Chemical communications (Cambridge, England) 20011021

• Lack of complex I activity in human cells carrying a mutation in MtDNA-encoded ND4 subunit is corrected by the Saccharomyces cerevisiae NADH-quinone oxidoreductase (NDI1) gene.

  The Journal of biological chemistry 20011019

• Negative control of p53 by Sir2alpha promotes cell survival under stress.

  Cell 20011019

• Effects of environment on flavin reactivity in morphinone reductase: analysis of enzymes displaying differential charge near the N-1 atom and C-2 carbonyl region of the active-site flavin.

  The Biochemical journal 20011015

• Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death.

  Proceedings of the National Academy of Sciences of the United States of America 20011009

• Conversion of a peroxiredoxin into a disulfide reductase by a triplet repeat expansion.

  Science (New York, N.Y.) 20011005

• Mechanisms of ascorbic acid recycling in human erythrocytes.

  Biochimica et biophysica acta 20011003

• The effect of carvedilol on enhanced ADP-ribosylation and red blood cell membrane damage caused by free radicals.

  Cardiovascular research 20011001

• Vitamin C and quinapril abrogate LVH and endothelial dysfunction in aortic-banded guinea pigs.

  American journal of physiology. Heart and circulatory physiology 20011001

• beta-Oxidation of simvastatin in mouse liver preparations.

  Drug metabolism and disposition: the biological fate of chemicals 20011001

• Nitric oxide inhibits mitochondrial NADH:ubiquinone reductase activity through peroxynitrite formation.

  The Biochemical journal 20011001

• Assimilatory nitrate reductase: lysine 741 participates in pyridine nucleotide binding via charge complementarity.

  Archives of biochemistry and biophysics 20011001

• Analysis of reactive oxygen species generating systems in rat epididymal spermatozoa.

  Biology of reproduction 20011001

• Effects of flavin-binding motif amino acid mutations in the NADH-cytochrome b5 reductase catalytic domain on protein stability and catalysis.

  Journal of biochemistry 20011001

• An enzymatic cycling method for the measurement of myo-inositol in biological samples.

  Clinica chimica acta; international journal of clinical chemistry 20011001

• Activities of enzymes related to the malate-aspartate shuttle in the blood cells of thoroughbred horses undergoing training exercise.

  Veterinary research communications 20011001

• Different effects of tert-butylhydroperoxide-induced peroxynitrite-dependent and -independent DNA single-strand breakage on PC12 cell poly(ADP-ribose) polymerase activity.

  European journal of biochemistry 20011001

• N-t-Butyl hydroxylamine is an antioxidant that reverses age-related changes in mitochondria in vivo and in vitro.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011001

• DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria.

  Journal of neurochemistry 20011001

• Optimizing the energy status of skin cells during solar radiation.

  Journal of photochemistry and photobiology. B, Biology 20011001

• Effects of MgATP on ATP utilization and force under normal and simulated ischaemic conditions in rat cardiac trabeculae.

  Pflugers Archiv : European journal of physiology 20011001

• Enzyme redesign.

  Chemical reviews 20011001

• Study of the properties of phosphorylating D-glyceraldehyde-3-phosphate dehydrogenase.

  Biochemistry. Biokhimiia 20011001

• Influence of adenine-induced renal failure on tryptophan-niacin metabolism in rats.

  Bioscience, biotechnology, and biochemistry 20011001

• Pyrimidine base catabolism in Pseudomonas putida biotype B.

  Antonie van Leeuwenhoek 20011001

• Structural and metabolic characteristic of nephrocytes during peritonitis of various genesis.

  Bulletin of experimental biology and medicine 20011001

• NAD+-dependent DNA ligase encoded by a eukaryotic virus.

  The Journal of biological chemistry 20010928

• Mycobacterium tuberculosis lipoamide dehydrogenase is encoded by Rv0462 and not by the lpdA or lpdB genes.

  Biochemistry 20010925

• 13C NMR analysis of electrostatic interactions between NAD+ and active site residues of UDP-galactose 4-epimerase: implications for the activation induced by uridine nucleotides.

  Biochemistry 20010918

• Effect of exogenous lactate on rat glioma metabolism.

  Journal of neuroscience research 20010915

• Oxidation of NADH by chloramines and chloramides and its activation by iodide and by tertiary amines.

  Archives of biochemistry and biophysics 20010915

• Glucose-induced oscillations in cytoplasmic free Ca2+ concentration precede oscillations in mitochondrial membrane potential in the pancreatic beta-cell.

  The Journal of biological chemistry 20010914

• Assimilation of D-malate by Rhodobacter capsulatus E1F1.

  Current microbiology 20010901

• Standardized measurements and differential spectroscopy in microplates.

  Analytical biochemistry 20010901

• Glyceraldehyde-3-phosphate dehydrogenase is negatively regulated by ADP-ribosylation in the fungus Phycomyces blakesleeanus.

  Microbiology (Reading, England) 20010901

• Is ischemia involved in the pathogenesis of murine cerebral malaria?

  The American journal of pathology 20010901

• Involvement of NADH/NADPH oxidase in human platelet ROS production.

  Thrombosis research 20010901

• Sensitivity of mitochondrial respiration to different inhibitors in Venturia inaequalis.

  Pest management science 20010901

• Glycerol dehydrogenase. structure, specificity, and mechanism of a family III polyol dehydrogenase.

  Structure (London, England : 1993) 20010901

• Desaturation reactions catalyzed by soluble methane monooxygenase.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20010901

• Effects of ADP on different inhibitory properties of brain glutamate dehydrogenase isoproteins by perphenazine.

  Biochimie 20010901

• Metabolism of NAD+ in nuclei of Saccharomyces cerevisiae during stimulation of its biosynthesis by nicotinamide.

  Biochemistry. Biokhimiia 20010901

• [The mechanism of action of isoniazid. A chemical model of activation].

  Annales pharmaceutiques francaises 20010901

• Protein-protein interaction using tryptophan analogues: novel spectroscopic probes for toxin-elongation factor-2 interactions.

  Biochemistry 20010828

• Transient-state and steady-state kinetic studies of the mechanism of NADH-dependent aldehyde reduction catalyzed by xylose reductase from the yeast Candida tenuis.

  Biochemistry 20010828

• Structural analyses of a malate dehydrogenase with a variable active site.

  The Journal of biological chemistry 20010817

• The heterotrimer of the membrane-peripheral components of transhydrogenase and the alternating-site mechanism of proton translocation.

  The Journal of biological chemistry 20010817

• Immunocyte Ca2+ influx system mediated by LTRPC2.

  Science (New York, N.Y.) 20010817

• Synthesis, mechanism of action, and antiviral activity of a new series of covalent mechanism-based inhibitors of S-adenosyl-L-homocysteine hydrolase.

  Journal of medicinal chemistry 20010816

• Adenine recognition: a motif present in ATP-, CoA-, NAD-, NADP-, and FAD-dependent proteins.

  Proteins 20010815

• Nicotinamide adenine dinucleotide (NAD) and its metabolites inhibit T lymphocyte proliferation: role of cell surface NAD glycohydrolase and pyrophosphatase activities.

  Journal of immunology (Baltimore, Md. : 1950) 20010815

• Phenotypic and genetic characterization of NAD-dependent Pasteurellaceae from the respiratory tract of pigs and their possible pathogenetic importance.

  Veterinary microbiology 20010808

• Mechanistic roles of Thr134, Tyr160, and Lys 164 in the reaction catalyzed by dTDP-glucose 4,6-dehydratase.

  Biochemistry 20010807

• Reaction of superoxide and nitric oxide with peroxynitrite. Implications for peroxynitrite-mediated oxidation reactions in vivo.

  The Journal of biological chemistry 20010803

• Extracellular NAD(+) induces calcium signaling and apoptosis in human osteoblastic cells.

  Biochemical and biophysical research communications 20010803

• Oxidative pentose phosphate pathway and pyridine nucleotides in relation to heartwood formation in Robinia pseudoacacia L.

  Phytochemistry 20010801

• A biochemical hypothesis explaining the response of enhanced biological phosphorus removal biomass to organic substrates.

  Water research 20010801

• Ca(2+)-calmodulin antagonist chlorpromazine and poly(ADP-ribose) polymerase modulators 4-aminobenzamide and nicotinamide influence hepatic expression of BCL-XL and P53 and protect against acetaminophen-induced programmed and unprogrammed cell death in mice.

  Free radical biology & medicine 20010801

• Site specificity and mechanism of oxidative DNA damage induced by carcinogenic catechol.

  Carcinogenesis 20010801

• A spectrophotometric assay for quantitative determination of kcat of herpes simplex virus type 1 thymidine kinase substrates.

  Analytical biochemistry 20010801

• Evidence of a role for cyclic ADP-ribose in calcium signalling and neurotransmitter release in cultured astrocytes.

  Journal of neurochemistry 20010801

• Effect of melatonin on cellular energy depletion mediated by peroxynitrite and poly (ADP-ribose) synthetase activation in an acute model of inflammation.

  Journal of pineal research 20010801

• Molecular characterization of Escherichia coli NAD kinase.

  European journal of biochemistry 20010801

• Azorhizobium caulinodans pyruvate dehydrogenase activity is dispensable for aerobic but required for microaerobic growth.

  Microbiology (Reading, England) 20010801

• Is a NAD pyrophosphatase activity necessary for Haemophilus influenzae type b multiplication in the blood stream?

  International journal of medical microbiology : IJMM 20010801

• Purification and characterization of L-2,3-butanediol dehydrogenase of Brevibacterium saccharolyticum C-1012 expressed in Escherichia coli.

  Bioscience, biotechnology, and biochemistry 20010801

• Metabolic control through L calcium channel, PKC and opioid receptors modulation by an association of naloxone and calcium salts.

  Current drug targets. Immune, endocrine and metabolic disorders 20010801

• The effect of ethanol on metabolic, hemodynamic and electrical responses to cortical spreading depression.

  Brain research 20010727

• Oxidative DNA damage by an N-hydroxy metabolite of the mutagenic compound formed from norharman and aniline.

  Mutation research 20010725

• Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors.

  Science (New York, N.Y.) 20010720

• GroEL-assisted dehydrogenase folding mediated by coenzyme is ATP-independent.

  Biochemical and biophysical research communications 20010713

• The first examples of (S)-2-hydroxyacid dehydrogenases catalyzing the transfer of the pro-4S hydrogen of NADH are found in the archaea.

  Biochimica et biophysica acta 20010709

• Functional coupling of PSST and ND1 subunits in NADH:ubiquinone oxidoreductase established by photoaffinity labeling.

  Biochimica et biophysica acta 20010702

• Diadenosine phosphates and S-adenosylmethionine: novel boron binding biomolecules detected by capillary electrophoresis.

  Biochimica et biophysica acta 20010702

• Simulation of cardiac work transitions, in vitro: effects of simultaneous Ca2+ and ATPase additions on isolated porcine heart mitochondria.

  Cell calcium 20010701

• Rapid induction of naive T cell apoptosis by ecto-nicotinamide adenine dinucleotide: requirement for mono(ADP-ribosyl)transferase 2 and a downstream effector.

  Journal of immunology (Baltimore, Md. : 1950) 20010701

• High-resolution neutron structure of nicotinamide adenine dinucleotide.

  Acta crystallographica. Section D, Biological crystallography 20010701

• Recycling of the ascorbate free radical by human erythrocyte membranes.

  Free radical biology & medicine 20010701

• The NADH-dependent reductase of a putative multicomponent tetrahydrofuran mono-oxygenase contains a covalently bound FAD.

  European journal of biochemistry 20010701

• Allosteric activation of pyruvate kinase via NAD+ in rat liver cells.

  European journal of biochemistry 20010701

• Modulation of VP-16 cytotoxicity by carboplatin and 41.8 degrees C hyperthermia.

  Journal of cancer research and clinical oncology 20010701

• Superoxide dismutase plays an important role in the survival of Lactobacillus sake upon exposure to elevated oxygen.

  Archives of microbiology 20010701

• Purification and properties of two malate dehydrogenases from Candida sp. N-16 grown on methanol.

  Bioscience, biotechnology, and biochemistry 20010701

• NAD and glutathione modulate sensitivity of bone marrow cells to oxidative stress.

  Bulletin of experimental biology and medicine 20010701

• Activity of key enzymes in microsomal and mitochondrial membranes depends on the redox reactions involving lipid radicals.

  Membrane & cell biology 20010701

• Effect of addition of proton carriers in culture medium on growth and secretion of hybridoma cell line OKT3.

  Indian journal of physiology and pharmacology 20010701

• Aspartate aminotransferase levels in gingival crevicular fluid before and after initial periodontal treatment.

  Journal of the International Academy of Periodontology 20010701

• Toxic effects of MPP(+) and MPTP in PC12 cells independent of reactive oxygen species formation.

  Brain research 20010629

• An interplay between the TOM complex and porin isoforms in the yeast Saccharomyces cerevisiae mitochondria.

  FEBS letters 20010629

• In vivo role of NAD(P)H:quinone oxidoreductase 1 (NQO1) in the regulation of intracellular redox state and accumulation of abdominal adipose tissue.

  The Journal of biological chemistry 20010622

• Melatonin activates the peroxidase-oxidase reaction and promotes oscillations.

  Biochemical and biophysical research communications 20010622

• NADH oxidase activity (NOX) and enlargement of HeLa cells oscillate with two different temperature-compensated period lengths of 22 and 24 minutes corresponding to different NOX forms.

  Biochimica et biophysica acta 20010620

• The A245K mutation exposes another stage of the bacterial L-lactate dehydrogenase reaction mechanism.

  Biochemistry 20010619

• Interaction of 11-cis-retinol dehydrogenase with the chromophore of retinal g protein-coupled receptor opsin.

  The Journal of biological chemistry 20010615

• Purification and catalytic properties of the chlorophenol 4-monooxygenase from Burkholderia cepacia strain AC1100.

  Biochimica et biophysica acta 20010611

• Probing catalysis by Escherichia coli dTDP-glucose-4,6-dehydratase: identification and preliminary characterization of functional amino acid residues at the active site.

  Biochemistry 20010605

• Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane.

  The Journal of biological chemistry 20010601

• Effect of poly(ADP-ribose) polymerase inhibitors on the ischemia-reperfusion-induced oxidative cell damage and mitochondrial metabolism in Langendorff heart perfusion system.

  Molecular pharmacology 20010601

• Enoyl-ACP reductase (FabI) of Haemophilus influenzae: steady-state kinetic mechanism and inhibition by triclosan and hexachlorophene.

  Archives of biochemistry and biophysics 20010601

• A high-capacity screen for adipogenic differentiation.

  Analytical biochemistry 20010601

• Inhibitory effects of nitric oxide on oxidative phosphorylation in plant mitochondria.

  Nitric oxide : biology and chemistry 20010601

• NADH: sensor of blood flow need in brain, muscle, and other tissues.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010601

• Biological processes, quantum mechanics and electromagnetic fields: the possibility of device-encapsulated human intention in medical therapies.

  Medical hypotheses 20010601

• Nicotinamide adenine dinucleotide-dependent retinoic acid formation from retinol in the human gastric mucosa: inhibition by ethanol, acetaldehyde, and H2 blockers.

  Alcoholism, clinical and experimental research 20010601

• Alcohol dehydrogenase activities in the human gastric mucosa: effects of Helicobacter pylori infection, sex, age, and the part of the stomach.

  Alcoholism, clinical and experimental research 20010601

• Effects of chronic alcohol consumption on hepatic poly-ADP-ribosylation in the rat.

  Alcoholism, clinical and experimental research 20010601

• Bacterial DNA ligases.

  Molecular microbiology 20010601

• Changes in activities of enzymes related to malate-aspartate shuttle in leukocytes from dogs given a herb supplement.

  The Journal of veterinary medical science 20010601

• Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats.

  Bioscience, biotechnology, and biochemistry 20010601

• Myocardial ischemic preconditioning in rodents is dependent on poly (ADP-ribose) synthetase.

  Molecular medicine (Cambridge, Mass.) 20010601

• [Effect of feeding with a poisonous mushroom Clitocybe acromelalga on the metabolism of tryptophan-niacin in rats].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20010601

• A quantitative analysis for the ADP-ribosylation activity of pertussis toxin: an enzymatic-HPLC coupled assay applicable to formulated whole cell and acellular pertussis vaccine products.

  Biologicals : journal of the International Association of Biological Standardization 20010601

• Methylenetetrahydrofolate reductase from Escherichia coli: elucidation of the kinetic mechanism by steady-state and rapid-reaction studies.

  Biochemistry 20010529

• Folate activation and catalysis in methylenetetrahydrofolate reductase from Escherichia coli: roles for aspartate 120 and glutamate 28.

  Biochemistry 20010529

• A study of the structure-activity relationship for diazaborine inhibition of Escherichia coli enoyl-ACP reductase.

  Journal of molecular biology 20010525

• Purification and characterization of a novel phosphorus-oxidizing enzyme from Pseudomonas stutzeri WM88.

  The Journal of biological chemistry 20010518

• Human oestrogenic 17beta-hydroxysteroid dehydrogenase specificity: enzyme regulation through an NADPH-dependent substrate inhibition towards the highly specific oestrone reduction.

  The Biochemical journal 20010515

• Regulation of glutamate dehydrogenase by reversible ADP-ribosylation in mitochondria.

  The EMBO journal 20010515

• NADH oxidase activity of mitochondrial apoptosis-inducing factor.

  The Journal of biological chemistry 20010511

• Human UDP-galactose 4-epimerase. Accommodation of UDP-N-acetylglucosamine within the active site.

  The Journal of biological chemistry 20010504

• In vitro effects of nicotine on mitochondrial respiration and superoxide anion generation.

  Brain research 20010504

• Simultaneous occurrence of two different glyceraldehyde-3-phosphate dehydrogenases in heterocystous N(2)-fixing cyanobacteria.

  Biochemical and biophysical research communications 20010504

• The 'strict' anaerobe Desulfovibrio gigas contains a membrane-bound oxygen-reducing respiratory chain.

  FEBS letters 20010504

• Catechol estrogens induce oxidative DNA damage and estradiol enhances cell proliferation.

  International journal of cancer 20010501

• Nitric oxide reduces energy supply by direct action on the respiratory chain in isolated cardiomyocytes.

  American journal of physiology. Heart and circulatory physiology 20010501

• Structure-function studies of human deoxyhypusine synthase: identification of amino acid residues critical for the binding of spermidine and NAD.

  The Biochemical journal 20010501

• Mycobacterium tuberculosis mycothione reductase: pH dependence of the kinetic parameters and kinetic isotope effects.

  Biochemistry 20010501

• Pyruvate : NADP+ oxidoreductase from the mitochondrion of Euglena gracilis and from the apicomplexan Cryptosporidium parvum: a biochemical relic linking pyruvate metabolism in mitochondriate and amitochondriate protists.

  Molecular biology and evolution 20010501

• Application of a fluorometric assay for characterization of the catalytic competency of a domain III fragment of Pseudomonas aeruginosa exotoxin A.

  Analytical biochemistry 20010501

• NADP+ and NAD+ binding to the dual coenzyme specific enzyme Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase: different interdomain hinge angles are seen in different binary and ternary complexes.

  Acta crystallographica. Section D, Biological crystallography 20010501

• Cytosolic redox metabolism in aerobic chemostat cultures of Saccharomyces cerevisiae.

  Yeast (Chichester, England) 20010501

• Voltammetric biosensors for the determination of formate and glucose-6-phosphate based on the measurement of dehydrogenase-generated NADH and NADPH.

  Biosensors & bioelectronics 20010501

• Generation of a proton potential by succinate dehydrogenase of Bacillus subtilis functioning as a fumarate reductase.

  European journal of biochemistry 20010501

• [NADH oxidase (peroxiredoxin reductase) in hydroperoxide scavenging system].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20010501

• [Oxygen metabolism and oxidative stress in lactic acid bacteria].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20010501

• Kinetic characterization of the rotenone-insensitive internal NADH: ubiquinone oxidoreductase of mitochondria from Saccharomyces cerevisiae.

  Archives of biochemistry and biophysics 20010501

• Standard apparent reduction potentials for biochemical half reactions as a function of pH and ionic strength.

  Archives of biochemistry and biophysics 20010501

• Multiparameter analysis of physiological changes in apoptosis.

  Current protocols in cytometry 20010501

• Structural basis for triclosan and NAD binding to enoyl-ACP reductase of Plasmodium falciparum.

  Biochemical and biophysical research communications 20010427

• Gas phase biotransformation reaction catalyzed by baker's yeast.

  Biotechnology and bioengineering 20010420

• Mitochondrial permeability transition and oxidative stress.

  FEBS letters 20010420

• Metabolite and enzyme profiles of glycogen metabolism in Methanococcoides methylutens.

  FEMS microbiology letters 20010420

• Mutational analyses of Aquifex pyrophilus DNA ligase define essential domains for self-adenylation and DNA binding activity.

  Archives of biochemistry and biophysics 20010415

• Characterization of mutants of beta histidine91, beta aspartate213, and beta asparagine222, possible components of the energy transduction pathway of the proton-translocating pyridine nucleotide transhydrogenase of Escherichia coli.

  Archives of biochemistry and biophysics 20010415

• Crystal structure of the MJ0490 gene product of the hyperthermophilic archaebacterium Methanococcus jannaschii, a novel member of the lactate/malate family of dehydrogenases.

  Journal of molecular biology 20010413

• Dynamics of protein ligand binding on multiple time scales: NADH binding to lactate dehydrogenase.

  Biochemistry 20010403

• Activity of one of two engineered heterodimers of AhpF, the NADH:peroxiredoxin oxidoreductase from Salmonella typhimurium, reveals intrasubunit electron transfer between domains.

  Biochemistry 20010403

• Inhibitory effect of sorbitol on sugar metabolism of Streptococcus mutans in vitro and on acid production in dental plaque in vivo.

  Oral microbiology and immunology 20010401

• Iodide and bromide inhibit Ca(2+) uptake by cardiac sarcoplasmic reticulum.

  American journal of physiology. Heart and circulatory physiology 20010401

• Direct imaging of dehydrogenase activity within living cells using enzyme-dependent fluorescence recovery after photobleaching (ED-FRAP).

  Biophysical journal 20010401

• Mass spectrometry as a novel approach to probe cooperativity in multimeric enzymatic systems.

  Analytical biochemistry 20010401

• Crystallization and preliminary X-ray analysis of dmpFG-encoded 4-hydroxy-2-ketovalerate aldolase--aldehyde dehydrogenase (acylating) from Pseudomonas sp. strain CF600.

  Acta crystallographica. Section D, Biological crystallography 20010401

• Mechanism of oxidative DNA damage induced by carcinogenic 4-aminobiphenyl.

  Free radical biology & medicine 20010401

• A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons.

  Journal of neurochemistry 20010401

• Mobilization of Ca2+ by cyclic ADP-ribose from the endoplasmic reticulum of cauliflower florets.

  Plant physiology 20010401

• Melatonin protects against streptozotocin, but not interleukin-1beta-induced damage of rodent pancreatic beta-cells.

  Journal of pineal research 20010401

• Quantitation of localized (31)P magnetic resonance spectra based on the reciprocity principle.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20010401

• Enhanced superoxide anion formation in vascular tissues from spontaneously hypertensive and desoxycorticosterone acetate-salt hypertensive rats.

  Journal of hypertension 20010401

• Assessment of chloroaniline toxicity by the submitochondrial particle assay.

  Environmental toxicology and chemistry 20010401

• Electrophilic methyl groups present in the diet ameliorate pathological states induced by reductive and oxidative stress: a hypothesis.

  The British journal of nutrition 20010401

• Catechol derivatives of aminopyrazine and cell protection against UVB-induced mortality.

  Bioorganic & medicinal chemistry 20010401

• Glucose-induced hyperproliferation of cultured rat aortic smooth muscle cells through polyol pathway hyperactivity.

  Diabetologia 20010401

• The NADH diphosphatase encoded by the Saccharomyces cerevisiae NPY1 nudix hydrolase gene is located in peroxisomes.

  Archives of biochemistry and biophysics 20010401

• Failure of exogenous NADH and cytochrome c to support energy-dependent swelling of mitochondria.

  Archives of biochemistry and biophysics 20010401

• Cytopathic hypoxia in sepsis: a true problem?

  Minerva anestesiologica 20010401

• Metabolic flux analysis of Clostridium thermosuccinogenes: effects of pH and culture redox potential.

  Applied biochemistry and biotechnology 20010401

• Under conditions of insufficient permeability of VDAC1, external NADH may use the TOM complex channel to cross the outer membrane of Saccharomyces cerevisiae mitochondria.

  Journal of bioenergetics and biomembranes 20010401

• Elevation of blood NAD level after moderate exercise in young women and mice.

  Journal of nutritional science and vitaminology 20010401

• NADH-dependent dehydroascorbate reductase in the rabbit lens.

  The Tokai journal of experimental and clinical medicine 20010401

• On the enzymatic activation of NADH.

  The Journal of biological chemistry 20010323

• Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation.

  Journal of molecular biology 20010323

• Phosphite dehydrogenase: an unusual phosphoryl transfer reaction.

  Journal of the American Chemical Society 20010321

• The crystal structure of dTDP-D-Glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar Typhimurium, the second enzyme in the dTDP-l-rhamnose pathway.

  Journal of molecular biology 20010316

• Effect of active shortening on the rate of ATP utilisation by rabbit psoas muscle fibres.

  The Journal of physiology 20010315

• Electron spin resonance characterization of the NAD(P)H oxidase in vascular smooth muscle cells.

  Free radical biology & medicine 20010315

• Conformation of NADH studied by fluorescence excitation transfer spectroscopy.

  Biophysical chemistry 20010315

• Photochemical generation of cyclopentadienyliron dicarbonyl anion by a nicotinamide adenine dinucleotide dimer analogue.

  Inorganic chemistry 20010312

• Dynamic responses of Pseudomonas fluorescens DF57 to nitrogen or carbon source addition.

  Journal of biotechnology 20010309

• Characterization of recombinant human nicotinamide mononucleotide adenylyl transferase (NMNAT), a nuclear enzyme essential for NAD synthesis.

  FEBS letters 20010309

• NAD/NADH models with axial/central chiralities: superiority of the quinoline ring system.

  The Journal of organic chemistry 20010309

• Interleukin-3 withdrawal induces an early increase in mitochondrial membrane potential unrelated to the Bcl-2 family. Roles of intracellular pH, ADP transport, and F(0)F(1)-ATPase.

  The Journal of biological chemistry 20010302

• Expression of NAD(+)-dependent isocitrate dehydrogenase in brown adipose tissue.

  Biochemical and biophysical research communications 20010302

• Glucose deprivation and chemical hypoxia: neuroprotection by P2 receptor antagonists.

  Neurochemistry international 20010301

• Active-site characterization of Candida boidinii formate dehydrogenase.

  The Biochemical journal 20010301

• Flux-balance analysis of mitochondrial energy metabolism: consequences of systemic stoichiometric constraints.

  American journal of physiology. Regulatory, integrative and comparative physiology 20010301

• Lysophosphatidylcholine increases the secretion of matrix metalloproteinase 2 through the activation of NADH/NADPH oxidase in cultured aortic endothelial cells.

  Atherosclerosis 20010301

• Crystal structure of rat biliverdin reductase.

  Nature structural biology 20010301

• Construction, separation and properties of hybrid hexamers of glutamate dehydrogenase in which five of the six subunits are contributed by the catalytically inert D165S.

  European journal of biochemistry 20010301

• Oxidation of polychlorinated benzenes by genetically engineered CYP101 (cytochrome P450(cam)).

  European journal of biochemistry 20010301

• Reduction of ubiquinone by lipoamide dehydrogenase. An antioxidant regenerating pathway.

  European journal of biochemistry 20010301

• Theoretical studies on the regulation of oxidative phosphorylation in intact tissues.

  Biochimica et biophysica acta 20010301

• Purification and characterization of the fatty acid synthase from Bugula neritina.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010301

• Cobas Mira S endpoint enzymatic assay for plasma formate.

  Journal of analytical toxicology 20010301

• Aromatic hydroxylation catalyzed by toluene 4-monooxygenase in organic solvent/aqueous buffer mixtures.

  Applied biochemistry and biotechnology 20010301

• Influence of glucose on glycerol metabolism by wild-type and mutant strains of Clostridium butyricum E5 grown in chemostat culture.

  Applied microbiology and biotechnology 20010301

• Facilitated electrochemical oxidation of NADH and its model compound at gold electrode modified with terminally substituted electroinactive self-assembled monolayers.

  Bioelectrochemistry (Amsterdam, Netherlands) 20010301

• Respiratory electron transport and light-induced energy transduction in membranes from the aerobic photosynthetic bacterium Roseobacter denitrificans.

  Archives of microbiology 20010301

• Protein thiol modification of glyceraldehyde-3-phosphate dehydrogenase and caspase-3 by nitric oxide.

  Current protein & peptide science 20010301

• Rapid screening of H(2)O(2) production by Mycoplasma mycoides and differentiation of European subsp. mycoides SC (small colony) isolates.

  Veterinary microbiology 20010226

• Paradoxical effects of copper and manganese on brain mitochondrial function.

  Life sciences 20010223

• Purification and characterization of aminopropionaldehyde dehydrogenase from Arthrobacter sp. TMP-1.

  FEMS microbiology letters 20010220

• A positively charged cluster formed in the heme-distal pocket of cytochrome P450nor is essential for interaction with NADH.

  The Journal of biological chemistry 20010216

• NAD+ inhibits the self-splicing of the group I intron.

  Biochemical and biophysical research communications 20010216

• Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide.

  Biochimica et biophysica acta 20010216

• Seven new mutations in the nicotinamide adenine dinucleotide reduced-cytochrome b(5) reductase gene leading to methemoglobinemia type I.

  Blood 20010215

• Differential transfers of reduced flavin cofactor and product by bacterial flavin reductase to luciferase.

  Biochemistry 20010213

• Substrate and cofactor binding to fluorescently labeled cytoplasmic malate dehydrogenase.

  Biochimica et biophysica acta 20010209

• The crystal structure of an asymmetric complex of the two nucleotide binding components of proton-translocating transhydrogenase.

  Structure (London, England : 1993) 20010207

• Intracellular fluxes in a recombinant xylose-utilizing Saccharomyces cerevisiae cultivated anaerobically at different dilution rates and feed concentrations.

  Biotechnology and bioengineering 20010205

• Vascular NAD(P)H oxidase is distinct from the phagocytic enzyme and modulates vascular reactivity control.

  American journal of physiology. Heart and circulatory physiology 20010201

• 6-formylpterin, a xanthine oxidase inhibitor, intracellularly generates reactive oxygen species involved in apoptosis and cell proliferation.

  Free radical biology & medicine 20010201

• The time-course of acid excretion, levels of fluorescence dependent on cellular nicotinamide adenine nucleotide and glycolytic intermediates of Streptococcus mutans cells exposed and not exposed to air in the presence of glucose and sorbitol.

  Oral microbiology and immunology 20010201

• Identification of many crystal forms of Aspergillus nidulans dehydroquinate synthase.

  Acta crystallographica. Section D, Biological crystallography 20010201

• Crystal structure of meso-2,3-butanediol dehydrogenase in a complex with NAD+ and inhibitor mercaptoethanol at 1.7 A resolution for understanding of chiral substrate recognition mechanisms.

  Journal of biochemistry 20010201

• Crystal structure of glucose dehydrogenase from Bacillus megaterium IWG3 at 1.7 A resolution.

  Journal of biochemistry 20010201

• Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum.

  Nature medicine 20010201

• Predominant 4-hydroxylation of estradiol by constitutive cytochrome P450s in the female ACI rat liver.

  Carcinogenesis 20010201

• Oxidases and reductases are involved in metronidazole sensitivity in Helicobacter pylori.

  The international journal of biochemistry & cell biology 20010201

• Characterization of the lys2 gene of Acremonium chrysogenum encoding a functional alpha-aminoadipate activating and reducing enzyme.

  Molecular & general genetics : MGG 20010201

• Cardiac energetics during ischaemia and the rationale for metabolic interventions.

  Coronary artery disease 20010201

• Stereoselective reduction with NADH model BNAH through chiral induction in cyclodextrins.

  Bioorganic chemistry 20010201

• Haliangicin, a novel antifungal metabolite produced by a marine myxobacterium. 1. Fermentation and biological characteristics.

  The Journal of antibiotics 20010201

• Order and disorder in mitochondrial aldehyde dehydrogenase.

  Chemico-biological interactions 20010130

• Interaction of sheep liver cytosolic aldehyde dehydrogenase with quercetin, resveratrol and diethylstilbestrol.

  Chemico-biological interactions 20010130

• Complexes of NADH with betaine aldehyde dehydrogenase from leaves of the plant Amaranthus hypochondriacus L.

  Chemico-biological interactions 20010130

• Interaction of human aldehyde dehydrogenase with aromatic substrates and ligands.

  Chemico-biological interactions 20010130

• Molecular dynamics simulation of class 3 aldehyde dehydrogenase.

  Chemico-biological interactions 20010130

• Crystal structure of sorbitol dehydrogenase.

  Chemico-biological interactions 20010130

• Ternary complexes of liver alcohol dehydrogenase.

  Chemico-biological interactions 20010130

• Bioinorganic and bioorganic studies of liver alcohol dehydrogenase.

  Chemico-biological interactions 20010130

• Genesis of Drosophila ADH: the shaping of the enzymatic activity from a SDR ancestor.

  Chemico-biological interactions 20010130

• Characterization and functional role of Saccharomyces cerevisiae 2,3-butanediol dehydrogenase.

  Chemico-biological interactions 20010130

• Kinetic effects of a single-amino acid mutation in a highly variable loop (residues 114-120) of class IV ADH.

  Chemico-biological interactions 20010130

• Mouse alcohol dehydrogenase 4: kinetic mechanism, substrate specificity and simulation of effects of ethanol on retinoid metabolism.

  Chemico-biological interactions 20010130

• 3alpha-Hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni: biological significance, three-dimensional structure and gene regulation.

  Chemico-biological interactions 20010130

• Coenzyme specificity of human monomeric carbonyl reductase: contribution of Lys-15, Ala-37 and Arg-38.

  Chemico-biological interactions 20010130

• Binding of pyridine coenzymes to the beta-subunit of the voltage sensitive potassium channels.

  Chemico-biological interactions 20010130

• Calcium activation of heart mitochondrial oxidative phosphorylation: rapid kinetics of mVO2, NADH, AND light scattering.

  The Journal of biological chemistry 20010126

• The reactive oxygen species--and Michael acceptor-inducible human aldo-keto reductase AKR1C1 reduces the alpha,beta-unsaturated aldehyde 4-hydroxy-2-nonenal to 1,4-dihydroxy-2-nonene.

  The Journal of biological chemistry 20010126

• Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperfusion of the heart.

  The Journal of biological chemistry 20010126

• Is the cancer protective effect correlated with growth inhibitions by green tea (-)-epigallocatechin gallate mediated through an antioxidant mechanism?

  Cancer letters 20010126

• An old but simple and efficient method to elucidate the oxidation mechanism of NAD(P)H model 1-Aryl-1,4-dihydronicotinamides by cations 2-methyl-5-nitroisoquinolium, tropylium, and xanthylium in aqueous solution.

  The Journal of organic chemistry 20010126

• A disubstituted NAD+ analogue is a nanomolar inhibitor of trypanosomal glyceraldehyde-3-phosphate dehydrogenase.

  Bioorganic & medicinal chemistry letters 20010122

• Expression of a cytoplasmic transhydrogenase in Saccharomyces cerevisiae results in formation of 2-oxoglutarate due to depletion of the NADPH pool.

  Yeast (Chichester, England) 20010115

• Oxidative DNA damage by a metabolite of carcinogenic 1-nitropyrene.

  Biochemical and biophysical research communications 20010112

• Homoserine dehydrogenase from Saccharomyces cerevisiae: kinetic mechanism and stereochemistry of hydride transfer.

  Biochimica et biophysica acta 20010112

• Crystal structure and novel recognition motif of rho ADP-ribosylating C3 exoenzyme from Clostridium botulinum: structural insights for recognition specificity and catalysis.

  Journal of molecular biology 20010105

• Use of a real-time, coupled assay to measure the ATPase activity of DNA topoisomerase II.

  Methods in molecular biology (Clifton, N.J.) 20010101

• Connexin 43 hemi channels mediate Ca2+-regulated transmembrane NAD+ fluxes in intact cells.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010101

• Changes in [Na(+)](i), compartmental [Ca(2+)], and NADH with dysfunction after global ischemia in intact hearts.

  American journal of physiology. Heart and circulatory physiology 20010101

• Molecular and physiological characterization of the NAD-dependent glycerol 3-phosphate dehydrogenase in the filamentous fungus Aspergillus nidulans.

  Molecular microbiology 20010101

• Extracellular cyclic ADP-ribose potentiates ACh-induced contraction in bovine tracheal smooth muscle.

  American journal of physiology. Lung cellular and molecular physiology 20010101

• Thiols can either enhance or suppress DNA damage induction by catecholestrogens.

  Free radical biology & medicine 20010101

• Metabolic fate of extracellular NAD in human skin fibroblasts.

  Journal of cellular biochemistry 20010101

• The nicotinamide biosynthetic pathway is a by-product of the RNA world.

  Journal of molecular evolution 20010101

• An organically modified silicate-based ethanol biosensor.

  Analytical biochemistry 20010101

• Inhibition of protein synthesis sequentially impairs distinct steps of stimulus-secretion coupling in pancreatic beta cells.

  Endocrinology 20010101

• Evolutionary optimization of metabolic pathways. Theoretical reconstruction of the stoichiometry of ATP and NADH producing systems.

  Bulletin of mathematical biology 20010101

• Melatonin protects against 6-OHDA-induced neurotoxicity in rats: a role for mitochondrial complex I activity.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010101

• Stoichiometry and compartmentation of NADH metabolism in Saccharomyces cerevisiae.

  FEMS microbiology reviews 20010101

• The biosynthesis of nicotinamide adenine dinucleotides in bacteria.

  Vitamins and hormones 20010101

• Apparent absence of a redox requirement for blue light activation of pump current in broad bean guard cells.

  Plant physiology 20010101

• Fatty acid chain elongation synthesis in eel (Anguilla anguilla) liver mitochondria.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010101

• Regulation of cyclosporin A sensitive mitochondrial permeability transition by the redox state of pyridine nucleotides.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010101

• Effects of nicotinamide coenzymes on the stability of enzyme activities and proteins in niacin-deficient quail tissues against trypsin treatment.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010101

• The best defense is a good offense--Salmonella deploys an ADP-ribosylating toxin.

  Trends in microbiology 20010101

• Oxidative DNA damage induced by an N-hydroxy metabolite of carcinogenic 4-dimethylaminoazobenzene.

  Japanese journal of cancer research : Gann 20010101

• Oxidative stress, metabolism of ethanol and alcohol-related diseases.

  Journal of biomedical science 20010101

• O-ADP-Ribosylation in the NAD/NADase system: 2-alkanols as efficient substrates.

  Chemical & pharmaceutical bulletin 20010101

• NADH-stimulated, cyanide-resistant superoxide production in maize coleoptiles analyzed with a tetrazolium-based assay.

  Planta 20010101

• Differences in intracellular sites of action of Adriamycin in neoplastic and normal differentiated cells.

  Cancer chemotherapy and pharmacology 20010101

• Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects.

  Teratogenesis, carcinogenesis, and mutagenesis 20010101

• Amperometric flow-injection determination of sucrose with a mediated tri-enzyme electrode based on sucrose phosphorylase and electrocatalytic oxidation of NADH.

  Biosensors & bioelectronics 20010101

• The effects of delta sleep-inducing peptide on the intensity of lipid peroxidation and xanthine oxidase activity in rat tissues during cold stress.

  Neuroscience and behavioral physiology 20010101

• Liver diseases by alcohol and hepatitis C: early detection and new insights in pathogenesis lead to improved treatment.

  The American journal on addictions 20010101

• Membrane-bound sugar alcohol dehydrogenase in acetic acid bacteria catalyzes L-ribulose formation and NAD-dependent ribitol dehydrogenase is independent of the oxidative fermentation.

  Bioscience, biotechnology, and biochemistry 20010101

• Diabetes-induced changes in retinal NAD-redox status: pharmacological modulation and implications for pathogenesis of diabetic retinopathy.

  Pharmacology 20010101

• Polymer modified electrodes for the reversible oxidation-reduction of NAD+/NADH for use within amperometric biosensors.

  Biomedical sciences instrumentation 20010101

• NADPH and NADH serve as electron donor for the superoxide-generating enzyme in tilapia (Oreochromis niloticus) neutrophils.

  Developmental and comparative immunology 20010101

• Ferredoxin:NADP oxidoreductase from Pyrococcus furiosus.

  Methods in enzymology 20010101

• A metabolic model for acetate uptake under anaerobic conditions by glycogen accumulating organisms: Stoichiometry, kinetics, and the effect of pH.

  Biotechnology and bioengineering 20010101

• Glutamate synthesis via photoreduction of NADP+ by photostable chlorophyllide coupled with polyethylene-glycol.

  Biotechnology and bioengineering 20010101

• In vivo ESR study on hepatic reduction of a nitroxide radical after administration of glucose in rats.

  IUBMB life 20010101

• Catalog of 434 single-nucleotide polymorphisms (SNPs) in genes of the alcohol dehydrogenase, glutathione S-transferase, and nicotinamide adenine dinucleotide, reduced (NADH) ubiquinone oxidoreductase families.

  Journal of human genetics 20010101

• The role of cerebral oedema in the pathogenesis of cerebral malaria.

  Redox report : communications in free radical research 20010101

• [Supramolecular regulation of the activity of some oxidoreductases in the norm and in pathology].

  Voprosy meditsinskoi khimii 20010101

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