-
Autophagy plays a pro-survival role against methamphetamine-induced apoptosis in H9C2 cells.
Toxicology letters 20180915
-
Effect of cyclosporine, tacrolimus and sirolimus on cellular senescence in renal epithelial cells.
Toxicology in vitro : an international journal published in association with BIBRA 20180401
-
Inhibition of autophagy enhances Hydroquinone-induced TK6 cell death.
Toxicology in vitro : an international journal published in association with BIBRA 20170601
-
Effect of exogenous TGF-β1 on the cadmium-induced nephrotoxicity by inhibiting apoptosis of proximal tubular cells through PI3K-AKT-mTOR signaling pathway.
Chemico-biological interactions 20170501
-
Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia.
American journal of human genetics 20170302
-
mTOR inhibition by rapamycin protects against deltamethrin-induced apoptosis in PC12 Cells.
Environmental toxicology 20170101
-
Phosphoramide mustard induces autophagy markers and mTOR inhibition prevents follicle loss due to phosphoramide mustard exposure.
Reproductive toxicology (Elmsford, N.Y.) 20170101
-
CWF-145, a novel synthetic quinolone derivative exerts potent antimitotic activity against human prostate cancer: Rapamycin enhances antimitotic drug-induced apoptosis through the inhibition of Akt/mTOR pathway.
Chemico-biological interactions 20161225
-
Basal autophagy protects cardiomyocytes from doxorubicin-induced toxicity.
Toxicology 20160831
-
Knockdown of NogoA prevents MPP+‑induced neurotoxicity in PC12 cells via the mTOR/STAT3 signaling pathway.
Molecular medicine reports 20160201
-
Impairment of the autophagic flux in astrocytes intoxicated by trimethyltin.
Neurotoxicology 20160101
-
Cabozantinib versus Everolimus in Advanced Renal-Cell Carcinoma.
The New England journal of medicine 20151105
-
The role of mTOR during cisplatin treatment in an in vitro and ex vivo model of cervical cancer.
Toxicology 20150901
-
Cannabidiol, a Cannabis sativa constituent, inhibits cocaine-induced seizures in mice: Possible role of the mTOR pathway and reduction in glutamate release.
Neurotoxicology 20150901
-
Activation of Autophagic Flux against Xenoestrogen Bisphenol-A-induced Hippocampal Neurodegeneration via AMP kinase (AMPK)/Mammalian Target of Rapamycin (mTOR) Pathways.
The Journal of biological chemistry 20150821
-
The mechanism of synergistic effects of arsenic trioxide and rapamycin in acute myeloid leukemia cell lines lacking typical t(15;17) translocation.
International journal of hematology 20150701
-
A comprehensively characterized large panel of head and neck cancer patient-derived xenografts identifies the mTOR inhibitor everolimus as potential new treatment option.
International journal of cancer 20150615
-
Synergistic effect of JQ1 and rapamycin for treatment of human osteosarcoma.
International journal of cancer 20150501
-
Key role of phosphodiesterase 4A (PDE4A) in autophagy triggered by yessotoxin.
Toxicology 20150302
-
mTOR inhibition improves immune function in the elderly.
Science translational medicine 20141224
-
The immunosuppressant tributyltin oxide blocks the mTOR pathway, like rapamycin, albeit by a different mechanism.
Journal of applied toxicology : JAT 20141201
-
A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy.
Nature chemical biology 20141201
-
The bromodomain and extra-terminal inhibitor CPI203 enhances the antiproliferative effects of rapamycin on human neuroendocrine tumors.
Cell death & disease 20141001
-
P-glycoprotein, CYP3A, and plasma carboxylesterase determine brain and blood disposition of the mTOR Inhibitor everolimus (Afinitor) in mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 20140615
-
A phase Ib trial of LY2584702 tosylate, a p70 S6 inhibitor, in combination with erlotinib or everolimus in patients with solid tumours.
European journal of cancer (Oxford, England : 1990) 20140301
-
Resveratrol prevents rapamycin-induced upregulation of autophagy and selectively induces apoptosis in TSC2-deficient cells.
Cell cycle (Georgetown, Tex.) 20140201
-
Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency.
Nature immunology 20140101
-
Conversion to sirolimus ameliorates cyclosporine-induced nephropathy in the rat: focus on serum, urine, gene, and protein renal expression biomarkers.
BioMed research international 20140101
-
Rapamycin attenuated cardiac hypertrophy induced by isoproterenol and maintained energy homeostasis via inhibiting NF-κB activation.
Mediators of inflammation 20140101
-
Autophagy maturation associated with CD38-mediated regulation of lysosome function in mouse glomerular podocytes.
Journal of cellular and molecular medicine 20131201
-
Activation of autophagy rescues amiodarone-induced apoptosis of lung epithelial cells and pulmonary toxicity in rats.
Toxicological sciences : an official journal of the Society of Toxicology 20131101
-
PI3Kδ inhibition augments the efficacy of rapamycin in suppressing proliferation of Epstein-Barr virus (EBV)+ B cell lymphomas.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20130801
-
Synergistic interactions between sorafenib and everolimus in pancreatic cancer xenografts in mice.
Cancer chemotherapy and pharmacology 20130501
-
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
The Biochemical journal 20130415
-
Inhibition of rapamycin-induced Akt phosphorylation by cotylenin A correlates with their synergistic growth inhibition of cancer cells.
International journal of oncology 20130201
-
Efficacy of RNA polymerase II inhibitors in targeting dormant leukaemia cells.
BMC pharmacology & toxicology 20130101
-
Enhancement of autophagy by simvastatin through inhibition of Rac1-mTOR signaling pathway in coronary arterial myocytes.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20130101
-
Arsenic trioxide overcomes rapamycin-induced feedback activation of AKT and ERK signaling to enhance the anti-tumor effects in breast cancer.
PloS one 20130101
-
Involvement of autophagy in the pharmacological effects of the mTOR inhibitor everolimus in acute kidney injury.
European journal of pharmacology 20121205
-
A phase I study of temozolomide and everolimus (RAD001) in patients with newly diagnosed and progressive glioblastoma either receiving or not receiving enzyme-inducing anticonvulsants: an NCIC CTG study.
Investigational new drugs 20121201
-
A phase II trial of temsirolimus in second-line metastatic urothelial cancer.
Medical oncology (Northwood, London, England) 20121201
-
Rapamycin treatment inhibits CHO cell death in a serum-free suspension culture by autophagy induction.
Biotechnology and bioengineering 20121201
-
Autophagy is a cell self-protective mechanism against arsenic-induced cell transformation.
Toxicological sciences : an official journal of the Society of Toxicology 20121201
-
The isoprenoid perillyl alcohol inhibits telomerase activity in prostate cancer cells.
Biochimie 20121201
-
Acute and sustained effects of a metabotropic glutamate 5 receptor antagonist in the novelty-suppressed feeding test.
Behavioural brain research 20121201
-
Enteric-delivered rapamycin enhances resistance of aged mice to pneumococcal pneumonia through reduced cellular senescence.
Experimental gerontology 20121201
-
The expression of URGCP gene in prostate cancer cell lines: correlation with rapamycin.
Molecular biology reports 20121201
-
Potential anti-aging agents suppress the level of constitutive mTOR- and DNA damage- signaling.
Aging 20121201
-
Efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 in a preclinical model of adrenocortical carcinoma.
Molecular and cellular endocrinology 20121125
-
Sirolimus solid self-microemulsifying pellets: formulation development, characterization and bioavailability evaluation.
International journal of pharmaceutics 20121115
-
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Bioorganic & medicinal chemistry 20121115
-
Randomized comparison of the Nobori biolimus A9-eluting stent with the sirolimus-eluting stent in patients with stenosis in native coronary arteries.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20121101
-
Phase II trial of temsirolimus in patients with metastatic breast cancer.
Breast cancer research and treatment 20121101
-
Remarkable inhibition of mTOR signaling by the combination of rapamycin and 1,4-phenylenebis(methylene)selenocyanate in human prostate cancer cells.
International journal of cancer 20121101
-
Influence of sirolimus-loaded nanoparticles on physiological functions of native human polymorphonuclear neutrophils.
Nanomedicine : nanotechnology, biology, and medicine 20121101
-
Role of autophagy inhibitors and inducers in modulating the toxicity of trimethyltin in neuronal cell cultures.
Journal of neural transmission (Vienna, Austria : 1996) 20121101
-
Rapamycin enhances dimethyl sulfoxide-mediated growth arrest in human myelogenous leukemia cells.
Leukemia & lymphoma 20121101
-
Acetylation of histone H3 prevents resistance development caused by chronic mTOR inhibition in renal cell carcinoma cells.
Cancer letters 20121101
-
Assessment of an asymmetrical coating stent with sirolimus released from ablumial matrix in porcine model.
Clinical research in cardiology : official journal of the German Cardiac Society 20121101
-
Anti-thymocyte globulin (thymoglobulin), tacrolimus, and sirolimus as acute graft-versus-host disease prophylaxis for unrelated hematopoietic stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20121101
-
Rapamycin-mediated suppression of renal cyst expansion in del34 Pkd1-/- mutant mouse embryos: an investigation of the feasibility of renal cyst prevention in the foetus.
Nephrology (Carlton, Vic.) 20121101
-
UV-visible spectroscopy as an alternative to liquid chromatography for determination of everolimus in surfactant-containing dissolution media: a useful approach based on solid-phase extraction.
Journal of pharmaceutical and biomedical analysis 20121101
-
Proliferation signal inhibitors in the treatment of lupus nephritis: preliminary experience.
Nephrology (Carlton, Vic.) 20121101
-
Pharmacological targeting of mammalian target of rapamycin inhibits ovarian granulosa cell tumor growth.
Carcinogenesis 20121101
-
Autophagy-dependent and -independent involvement of AMP-activated protein kinase in 6-hydroxydopamine toxicity to SH-SY5Y neuroblastoma cells.
Biochimica et biophysica acta 20121101
-
A dose escalation trial for the combination of erlotinib and sirolimus for recurrent malignant gliomas.
Journal of neuro-oncology 20121101
-
NVP-BEZ235 alone and in combination in mantle cell lymphoma: an effective therapeutic strategy.
Expert opinion on investigational drugs 20121101
-
Autophagy modulators sensitize prostate epithelial cancer cell lines to TNF-alpha-dependent apoptosis.
Apoptosis : an international journal on programmed cell death 20121101
-
Towards excellence in revascularization for left main coronary artery disease.
Current opinion in cardiology 20121101
-
Everolimus synergizes with gefitinib in non-small-cell lung cancer cell lines resistant to epidermal growth factor receptor tyrosine kinase inhibitors.
Cancer chemotherapy and pharmacology 20121101
-
A drug safety evaluation of everolimus in kidney transplantation.
Expert opinion on drug safety 20121101
-
Endothelial progenitor cell response to antiproliferative drug exposure.
Atherosclerosis 20121101
-
Phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway inhibition: a breakthrough in the management of luminal (ER+/HER2-) breast cancers?
Current opinion in oncology 20121101
-
Prolonged response using gefitinib followed by sirolimus for advanced cutaneous squamous cell carcinoma.
Journal of the American Academy of Dermatology 20121101
-
Topical sirolimus for oral pemphigus vulgaris: 3 unresponsive cases.
Journal of the American Academy of Dermatology 20121101
-
Hemodialysis does not affect everolimus pharmacokinetics: two cases of patients with metastatic renal cell cancer.
Annals of oncology : official journal of the European Society for Medical Oncology 20121101
-
Bioanalytical method validation of rapamycin in ocular matrix by QTRAP LC-MS/MS: application to rabbit anterior tissue distribution by topical administration of rapamycin nanomicellar formulation.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20121101
-
Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice.
Neuroscience 20121025
-
Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia.
Blood 20121025
-
Mammalian target of rapamycin signaling is a key regulator of the transit-amplifying progenitor pool in the adult and aging forebrain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20121024
-
Stent thrombosis and major clinical events at 3 years after zotarolimus-eluting or sirolimus-eluting coronary stent implantation: a randomised, multicentre, open-label, controlled trial.
Lancet (London, England) 20121020
-
Sirolimus and skin-cancer prevention in kidney transplantation.
The New England journal of medicine 20121018
-
Clinical and histopathologic characteristics of rash in cancer patients treated with mammalian target of rapamycin inhibitors.
Cancer 20121015
-
Phase I study of the antiangiogenic antibody bevacizumab and the mTOR/hypoxia-inducible factor inhibitor temsirolimus combined with liposomal doxorubicin: tolerance and biological activity.
Clinical cancer research : an official journal of the American Association for Cancer Research 20121015
-
A comprehensive review of everolimus clinical reports: a new mammalian target of rapamycin inhibitor.
Transplantation 20121015
-
Genome sequencing identifies a basis for everolimus sensitivity.
Science (New York, N.Y.) 20121012
-
Mammalian target of rapamycin regulates neutrophil extracellular trap formation via induction of hypoxia-inducible factor 1 α.
Blood 20121011
-
Pharmacokinetic study of 3-in-1 poly(ethylene glycol)-block-poly(D, L-lactic acid) micelles carrying paclitaxel, 17-allylamino-17-demethoxygeldanamycin, and rapamycin.
Journal of controlled release : official journal of the Controlled Release Society 20121010
-
A new strategy for discontinuation of dual antiplatelet therapy: the RESET Trial (REal Safety and Efficacy of 3-month dual antiplatelet Therapy following Endeavor zotarolimus-eluting stent implantation).
Journal of the American College of Cardiology 20121009
-
Prevention of alveolar destruction and airspace enlargement in a mouse model of pulmonary lymphangioleiomyomatosis (LAM).
Science translational medicine 20121003
-
Sustained clinical effectiveness and favorable safety profile of topical sirolimus for tuberous sclerosis - associated facial angiofibroma.
Journal of the European Academy of Dermatology and Venereology : JEADV 20121001
-
Phase I study of temsirolimus in combination with EKB-569 in patients with advanced solid tumors.
Investigational new drugs 20121001
-
Sirolimus- versus paclitaxel-eluting stents for coronary bifurcations intervention: a meta-analysis of five clinical trials.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20121001
-
The XIENCE nano everolimus eluting coronary stent system for the treatment of small coronary arteries: the SPIRIT Small Vessel trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20121001
-
Rapamycin blocks hepatoblastoma growth in vitro and in vivo implicating new treatment options in high-risk patients.
European journal of cancer (Oxford, England : 1990) 20121001
-
The impact of prophylactic antiviral agents and statin administration on graft longevity in kidney allograft recipients.
Immunopharmacology and immunotoxicology 20121001
-
Phase II study of everolimus in patients with locally advanced or metastatic transitional cell carcinoma of the urothelial tract: clinical activity, molecular response, and biomarkers.
Annals of oncology : official journal of the European Society for Medical Oncology 20121001
-
Effects of FTY720 and rapamycin on inflammation in taurocholate-induced acute pancreatitis in the rat.
Pancreas 20121001
-
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones.
Cancer letters 20121001
-
Antitumor effect of the mTOR inhibitor everolimus in combination with trastuzumab on human breast cancer stem cells in vitro and in vivo.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20121001
-
Neoadjuvant therapy of renal cell carcinoma: a novel treatment option in the era of targeted therapy?
International journal of urology : official journal of the Japanese Urological Association 20121001
-
Tolerability and pharmacokinetics of intravitreal sirolimus.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20121001
-
Novel agents in Hodgkin lymphoma.
Current oncology reports 20121001
-
NEX-TRAP, a novel method for in vivo analysis of nuclear export of proteins.
Traffic (Copenhagen, Denmark) 20121001
-
Combined blockade of signalling pathways shows marked anti-tumour potential in phaeochromocytoma cell lines.
Journal of molecular endocrinology 20121001
-
Phase I study of pasireotide (SOM 230) and everolimus (RAD001) in advanced neuroendocrine tumors.
Endocrine-related cancer 20121001
-
Impact of the first-generation drug-eluting stent implantation on periprocedural myocardial injury in patients with stable angina pectoris.
Journal of cardiology 20121001
-
Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide-cGMP and PI3K/mTOR pathways.
Behavioural brain research 20121001
-
Macroautophagy can press a brake on presynaptic neurotransmission.
Autophagy 20121001
-
Ischemic postconditioning during reperfusion attenuates intestinal injury and mucosal cell apoptosis by inhibiting JAK/STAT signaling activation.
Shock (Augusta, Ga.) 20121001
-
Effects of sotrastaurin, mycophenolic acid and everolimus on human B-lymphocyte function and activation.
Transplant international : official journal of the European Society for Organ Transplantation 20121001
-
Serial change and its determinants of residual plaque characteristics under sirolimus-eluting stent: a coronary angioscopic study.
Journal of cardiology 20121001
-
Luteinizing hormone/human chorionic gonadotropin-mediated activation of mTORC1 signaling is required for androgen synthesis by theca-interstitial cells.
Molecular endocrinology (Baltimore, Md.) 20121001
-
Disrupting the mTOR signaling network as a potential strategy for the enhancement of cancer radiotherapy.
Current cancer drug targets 20121001
-
IL-22 induced cell proliferation is regulated by PI3K/Akt/mTOR signaling cascade.
Cytokine 20121001
-
Everolimus for advanced pancreatic neuroendocrine tumours: a subgroup analysis evaluating Japanese patients in the RADIANT-3 trial.
Japanese journal of clinical oncology 20121001
-
Association of sirolimus adverse effects with m-TOR, p70S6K or Raptor polymorphisms in kidney transplant recipients.
Pharmacogenetics and genomics 20121001
-
Everolimus for the treatment of pancreatic neuroendocrine tumors.
Expert opinion on pharmacotherapy 20121001
-
FLT-PET is superior to FDG-PET for very early response prediction in NPM-ALK-positive lymphoma treated with targeted therapy.
Cancer research 20121001
-
Hypoxia induces autophagy in primary human trophoblasts.
Endocrinology 20121001
-
A single supratherapeutic dose of ridaforolimus does not prolong the QTc interval in patients with advanced cancer.
Cancer chemotherapy and pharmacology 20121001
-
A phase I study of erlotinib and hydroxychloroquine in advanced non-small-cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20121001
-
Counteracting autophagy overcomes resistance to everolimus in mantle cell lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20121001
-
Everolimus in pediatric transplantation.
Current opinion in organ transplantation 20121001
-
Antitumor activity of Triolimus: a novel multidrug-loaded micelle containing Paclitaxel, Rapamycin, and 17-AAG.
Molecular cancer therapeutics 20121001
-
Analysis of cyclosporin A, tacrolimus, sirolimus, and everolimus in dried blood spot samples using liquid chromatography tandem mass spectrometry.
Analytical and bioanalytical chemistry 20121001
-
Targeting androgen receptor leads to suppression of prostate cancer via induction of autophagy.
The Journal of urology 20121001
-
Preventive and therapeutic effects of rapamycin, a mammalian target of rapamycin inhibitor, on food allergy in mice.
Allergy 20121001
-
Arsenic trioxide synergizes with everolimus (Rad001) to induce cytotoxicity of ovarian cancer cells through increased autophagy and apoptosis.
Endocrine-related cancer 20121001
-
An evaluation of sirolimus in renal transplantation.
Expert opinion on drug metabolism & toxicology 20121001
-
Everolimus and erlotinib as second- or third-line therapy in patients with advanced non-small-cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20121001
-
Target of rapamycin (TOR) controls vitellogenesis via activation of the S6 kinase in the fat body of the tick, Haemaphysalis longicornis.
International journal for parasitology 20121001
-
Successful sirolimus graded dose challenge in an erythromycin-allergic patient.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20121001
-
Sirolimus in renal transplantation: analysis of safety and efficacy in a nonprotocol conversion group.
Transplantation proceedings 20121001
-
Sirolimus as rescue therapy after liver transplantation.
Transplantation proceedings 20121001
-
Pain syndrome induced by calcineurin inhibitor and resolved by conversion to sirolimus in a child after kidney transplantation: a case report.
Transplantation proceedings 20121001
-
Topical use of rapamycin in herpetic stromal keratitis.
Ocular immunology and inflammation 20121001
-
Comparison of twelve-month outcomes after percutanous coronary intervention with everolimus-eluting versus zotarolimus-eluting or sirolimus-eluting stents from the PROENCY (PROmus ENdeavor CYpher) registry.
The Journal of invasive cardiology 20121001
-
Late stent thrombosis of a second-generation drug- eluting stent.
The Journal of invasive cardiology 20121001
-
Comparison of paclitaxal vs. sirolimus eluting stents with bio-degradable polymer for the treatment of coronary bifurcation lesions: subgroup analysis from DKCRUSH-I and DKCRUSH-II studies.
Chinese medical journal 20121001
-
Vascular healing in drug-eluting stents: differential drug-associated response of limus-eluting stents in a preclinical model of stent implantation.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20121001
-
Enhanced drug delivery capabilities from stents coated with absorbable polymer and crystalline drug.
Journal of controlled release : official journal of the Controlled Release Society 20120928
-
Folate-conjugated rapamycin slows progression of polycystic kidney disease.
Journal of the American Society of Nephrology : JASN 20120928
-
Tuberin inhibits production of the matrix protein fibronectin in diabetes.
Journal of the American Society of Nephrology : JASN 20120928
-
Targeting of mTORC1/2 by the mTOR kinase inhibitor PP242 induces apoptosis in AML cells under conditions mimicking the bone marrow microenvironment.
Blood 20120927
-
Wound healing complications and the use of mammalian target of rapamycin inhibitors in kidney transplantation: a critical review of the literature.
Transplantation 20120927
-
An elaborate regulation of Mammalian target of rapamycin activity is required for somatic cell reprogramming induced by defined transcription factors.
Stem cells and development 20120920
-
Serum lactate dehydrogenase predicts for overall survival benefit in patients with metastatic renal cell carcinoma treated with inhibition of mammalian target of rapamycin.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120920
-
Rapamycin impairs UV induction of mutant-p53 overexpressing cell clusters without affecting tumor onset.
International journal of cancer 20120915
-
Co-administration strategy to enhance brain accumulation of vandetanib by modulating P-glycoprotein (P-gp/Abcb1) and breast cancer resistance protein (Bcrp1/Abcg2) mediated efflux with m-TOR inhibitors.
International journal of pharmaceutics 20120915
-
Cost-effectiveness of everolimus- versus paclitaxel-eluting stents for patients undergoing percutaneous coronary revascularization (from the SPIRIT-IV Trial).
The American journal of cardiology 20120915
-
Immunomodulatory synergy by combining atorvastatin and rapamycin in the treatment of experimental autoimmune encephalomyelitis (EAE).
Journal of neuroimmunology 20120915
-
Human TSC-associated renal angiomyolipoma cells are hypersensitive to ER stress.
American journal of physiology. Renal physiology 20120915
-
Leptin-induced mTOR activation defines a specific molecular and transcriptional signature controlling CD4+ effector T cell responses.
Journal of immunology (Baltimore, Md. : 1950) 20120915
-
Heme oxygenase-1 promotes survival of renal cancer cells through modulation of apoptosis- and autophagy-regulating molecules.
The Journal of biological chemistry 20120914
-
mTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis.
Cell stem cell 20120907
-
Rapamycin down-regulates KCC2 expression and increases seizure susceptibility to convulsants in immature rats.
Neuroscience 20120906
-
A neurotrophic hypothesis of depression: role of synaptogenesis in the actions of NMDA receptor antagonists.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20120905
-
Rapamycin delays disease onset and prevents PrP plaque deposition in a mouse model of Gerstmann-Sträussler-Scheinker disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20120905
-
Antileukaemia effect of rapamycin alone or in combination with daunorubicin on Ph+ acute lymphoblastic leukaemia cell line.
Hematological oncology 20120901
-
Central pontine myelinolysis: a case report and clinical-pathological review.
Pediatric transplantation 20120901
-
Castleman disease in a pediatric liver transplant recipient: a case report and literature review.
Pediatric transplantation 20120901
-
Successful sirolimus rescue in tacrolimus-induced thrombotic microangiopathy after living-related liver transplantation.
Pediatric transplantation 20120901
-
In vivo comparison of a polymer-free Biolimus A9-eluting stent with a biodegradable polymer-based Biolimus A9 eluting stent and a bare metal stent in balloon denuded and radiated hypercholesterolemic rabbit iliac arteries.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120901
-
Randomized comparison of cost-saving and effectiveness of oral rapamycin plus bare-metal stents with drug-eluting stents: three-year outcome from the randomized oral rapamycin in Argentina (ORAR) III trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120901
-
Sirolimus - moving toward the mainstream in pediatric heart transplantation?
Pediatric transplantation 20120901
-
K-Ras mutation-mediated IGF-1-induced feedback ERK activation contributes to the rapalog resistance in pancreatic ductal adenocarcinomas.
Cancer letters 20120901
-
Enduring response to everolimus as third-line therapy in a patient with advanced renal cell carcinoma, including small-bowel metastases: loss of FHIT but normal VHL gene status.
Clinical genitourinary cancer 20120901
-
Repetitive angioscopic observations of a sirolimus-eluting stent deployed in a patient with silent chronic thrombotic occlusion.
Cardiovascular intervention and therapeutics 20120901
-
The development of novel biodegradable bifurcation stents for the sustainable release of anti-proliferative sirolimus.
Annals of biomedical engineering 20120901
-
Indications for an alternative effective treatment of head and neck squamous cell carcinoma with temsirolimus plus bevacizumab: from bench to bedside?
Anti-cancer drugs 20120901
-
Post-transplantation encapsulating peritoneal sclerosis in a pediatric patient.
Pediatric nephrology (Berlin, Germany) 20120901
-
The novel combination of sirolimus and bortezomib prevents graft-versus-host disease but maintains the graft-versus-leukemia effect after allogeneic transplantation.
Haematologica 20120901
-
Conversion to sirolimus in pediatric renal transplant patients: a single-center experience.
Pediatric transplantation 20120901
-
Safety of posaconazole and sirolimus coadministration in allogeneic hematopoietic stem cell transplants.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120901
-
Characterization of Foxp3 gene from grass carp (Ctenopharyngodon idellus): a rapamycin-inducible transcription factor in teleost immune system.
Developmental and comparative immunology 20120901
-
Role of Toll-like receptor 2 in the immune response against hepadnaviral infection.
Journal of hepatology 20120901
-
Case of complete response to everolimus for metastatic renal cell carcinoma.
International journal of urology : official journal of the Japanese Urological Association 20120901
-
The long-term efficacy of cilostazol in addition to dual antiplatelet therapy after sirolimus-eluting stent implantation for Japanese patients: an analysis of the 3-year follow-up outcomes from the j-Cypher registry.
Cardiovascular intervention and therapeutics 20120901
-
Sirolimus: more cause for alarm?
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120901
-
Impact of sirolimus and tacrolimus on mortality and graft loss in liver transplant recipients with or without hepatitis C virus: an analysis of the Scientific Registry of Transplant Recipients Database.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120901
-
Reduced intensity allogeneic hematopoietic stem cell transplantation for MDS using tacrolimus/sirolimus-based GVHD prophylaxis.
Leukemia research 20120901
-
Sorafenib enhances the therapeutic efficacy of rapamycin in colorectal cancers harboring oncogenic KRAS and PIK3CA.
Carcinogenesis 20120901
-
Contractile activity-induced mitochondrial biogenesis and mTORC1.
American journal of physiology. Cell physiology 20120901
-
Efficacy of everolimus, a novel mTOR inhibitor, against basal-like triple-negative breast cancer cells.
Cancer science 20120901
-
Rapamycin induces p53-independent apoptosis through the mitochondrial pathway in non-small cell lung cancer cells.
Oncology reports 20120901
-
Rapamycin/IL-2 combination therapy in patients with type 1 diabetes augments Tregs yet transiently impairs β-cell function.
Diabetes 20120901
-
Cap-dependent mRNA translation and the ubiquitin-proteasome system cooperate to promote ERBB2-dependent esophageal cancer phenotype.
Cancer gene therapy 20120901
-
Development of a lymphangioleiomyomatosis model by endonasal administration of human TSC2-/- smooth muscle cells in mice.
The American journal of pathology 20120901
-
Randomized controlled trial of sirolimus conversion in cardiac transplant recipients with renal insufficiency.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120901
-
Rapamycin for treatment of type I autosomal dominant polycystic kidney disease (RAPYD-study): a randomized, controlled study.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120901
-
PDGF receptor alpha is an alternative mediator of rapamycin-induced Akt activation: implications for combination targeted therapy of synovial sarcoma.
Cancer research 20120901
-
Effect of immunosuppressive drugs on spontaneous DNA repair in human peripheral blood mononuclear cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20120901
-
Does everolimus increase donor-specific HLA antibodies in kidney transplant recipients?
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120901
-
Dual targeting of the Akt/mTOR signaling pathway inhibits castration-resistant prostate cancer in a genetically engineered mouse model.
Cancer research 20120901
-
Dual targeting of mTOR and aurora-A kinase for the treatment of uterine Leiomyosarcoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20120901
-
Perifosine enhances mTORC1-targeted cancer therapy by activation of GSK3β in NSCLC cells.
Cancer biology & therapy 20120901
-
Serum and glucocorticoid-regulated kinase 1 (SGK1) activation in breast cancer: requirement for mTORC1 activity associates with ER-alpha expression.
Breast cancer research and treatment 20120901
-
Phase II study of the safety and efficacy of temsirolimus in East Asian patients with advanced renal cell carcinoma.
Japanese journal of clinical oncology 20120901
-
Temsirolimus: a safety and efficacy review.
Expert opinion on drug safety 20120901
-
Phase I studies of sirolimus alone or in combination with pharmacokinetic modulators in advanced cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 20120901
-
ESX-1 dependent impairment of autophagic flux by Mycobacterium tuberculosis in human dendritic cells.
Autophagy 20120901
-
Inhibition of mTOR in carcinoid tumors.
Targeted oncology 20120901
-
A novel image-based cytometry method for autophagy detection in living cells.
Autophagy 20120901
-
The role of mTOR signaling pathway in spinal cord injury.
Cell cycle (Georgetown, Tex.) 20120901
-
Incidence and risk of pulmonary toxicity in patients treated with mTOR inhibitors for malignancy. A meta-analysis of published trials.
Acta oncologica (Stockholm, Sweden) 20120901
-
Renal angiomyolipomatosis and Kaposi's sarcoma: a possible link disrupted by sirolimus.
Internal and emergency medicine 20120901
-
Resistance to targeted therapies in pancreatic neuroendocrine tumors (PNETs): molecular basis, preclinical data, and counteracting strategies.
Targeted oncology 20120901
-
Immunotherapy in type 1 diabetes: a shorter but more winding road?
Diabetes 20120901
-
Topical rapamycin therapy to alleviate the cutaneous manifestations of tuberous sclerosis complex: a double-blind, randomized, controlled trial to evaluate the safety and efficacy of topically applied rapamycin.
Drugs in R&D 20120901
-
Everolimus: a new treatment option for advanced pancreatic neuroendocrine tumors.
The Annals of pharmacotherapy 20120901
-
Conversion from calcineurin inhibitors to everolimus with low-dose cyclosporine in renal transplant recipients with squamous cell carcinoma of the skin.
Transplantation proceedings 20120901
-
Everolimus and enteric-coated mycophenolate sodium ab initio after liver transplantation: midterm results.
Transplantation proceedings 20120901
-
Caffeine induces apoptosis of osteosarcoma cells by inhibiting AKT/mTOR/S6K, NF-κB and MAPK pathways.
Anticancer research 20120901
-
Comparative evaluation of small-molecule chemosensitizers in reversal of cisplatin resistance in ovarian cancer cells.
Anticancer research 20120901
-
Long-term vascular healing in response to sirolimus- and paclitaxel-eluting stents: an optical coherence tomography study.
JACC. Cardiovascular interventions 20120901
-
[Treatment of pulmonary and retroperitoneal lymphangioleiomyomatosis with rapamycin: a case presentation and literature review].
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20120901
-
Drug choices in autoimmune hepatitis: part B--Nonsteroids.
Expert review of gastroenterology & hepatology 20120901
-
Emerging agents for the treatment of mantle cell lymphoma.
Expert review of anticancer therapy 20120901
-
Clinical trial end points for assessing efficacy of novel therapies for soft-tissue sarcomas.
Expert review of anticancer therapy 20120901
-
Intranasal rapamycin rescues mice from staphylococcal enterotoxin B-induced shock.
Toxins 20120901
-
Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice.
Nature 20120830
-
Effectiveness of a combination therapy using calcineurin inhibitor and mTOR inhibitor in preventing allograft rejection and post-transplantation renal cancer progression.
Cancer letters 20120828
-
Constitutive activation of the mTOR signaling pathway within the normal glomerulus.
Biochemical and biophysical research communications 20120824
-
Effect of biolimus-eluting stents with biodegradable polymer vs bare-metal stents on cardiovascular events among patients with acute myocardial infarction: the COMFORTABLE AMI randomized trial.
JAMA 20120822
-
New-generation drug-eluting stents for patients with myocardial infarction.
JAMA 20120822
-
Resistance to the mTOR-inhibitor RAD001 elevates integrin α2- and β1-triggered motility, migration and invasion of prostate cancer cells.
British journal of cancer 20120821
-
Metabotropic actions of the volatile anaesthetic sevoflurane increase protein kinase M synthesis and induce immediate preconditioning protection of rat hippocampal slices.
The Journal of physiology 20120815
-
Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan.
American journal of physiology. Endocrinology and metabolism 20120815
-
The mTOR-inhibitor rapamycin mediates proteinuria in nephrotoxic serum nephritis by activating the innate immune response.
American journal of physiology. Renal physiology 20120815
-
Multiple roles for mammalian target of rapamycin signaling in both glutamatergic and GABAergic synaptic transmission.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20120815
-
Resolution of chylous pulmonary congestion and respiratory failure in lymphangioleiomyomatosis with sirolimus therapy.
American journal of respiratory and critical care medicine 20120815
-
Sirolimus-eluting stents for treatment of infrapopliteal arteries reduce clinical event rate compared to bare-metal stents: long-term results from a randomized trial.
Journal of the American College of Cardiology 20120814
-
Stent elution rate determines drug deposition and receptor-mediated effects.
Journal of controlled release : official journal of the Controlled Release Society 20120810
-
Efficacy of rapamycin for refractory hemangioendotheliomas in Maffucci's syndrome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120810
-
Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons.
Neuron 20120809
-
The Cdc48 protein and its cofactor Vms1 are involved in Cdc13 protein degradation.
The Journal of biological chemistry 20120803
-
Sirolimus and everolimus intestinal absorption and interaction with calcineurin inhibitors: a differential effect between cyclosporine and tacrolimus.
Fundamental & clinical pharmacology 20120801
-
Dietary restriction but not rapamycin extends disease onset and survival of the H46R/H48Q mouse model of ALS.
Neurobiology of aging 20120801
-
Unprotected left main coronary artery stenting with zotarolimus (Endeavor) drug-eluting stents: a single center retrospective experience.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120801
-
Phase I and pharmacokinetic study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced solid malignancies.
Investigational new drugs 20120801
-
A role for maintenance therapy in managing sarcoma.
Cancer treatment reviews 20120801
-
Optical coherence tomographic comparison of neointimal coverage between sirolimus- and resolute zotarolimus-eluting stents at 9 months after stent implantation.
The international journal of cardiovascular imaging 20120801
-
Analysis of 1 year virtual histology changes in coronary plaque located behind the struts of the everolimus eluting bioresorbable vascular scaffold.
The international journal of cardiovascular imaging 20120801
-
Frequency and impact of bleeding in elective coronary stent clinical trials--utility of three commonly used definitions.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120801
-
Rapamycin inhibits transforming growth factor β-induced peritoneal angiogenesis by blocking the secondary hypoxic response.
Journal of cellular and molecular medicine 20120801
-
PKI-587 and sorafenib targeting PI3K/AKT/mTOR and Ras/Raf/MAPK pathways synergistically inhibit HCC cell proliferation.
The Journal of surgical research 20120801
-
Rapamycin induced ultrastructural and molecular alterations in glomerular podocytes in healthy mice.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120801
-
Rapamycin induces heme oxygenase-1 in liver but inhibits bile flow recovery after ischemia.
The Journal of surgical research 20120801
-
Mao-B elevation decreases parkin's ability to efficiently clear damaged mitochondria: protective effects of rapamycin.
Free radical research 20120801
-
Treatment of coronary bifurcation lesions with drug-eluting stents: insights from the first phase of the prospective multicenter german drug-eluting stent registry.
Journal of interventional cardiology 20120801
-
Rapamycin inhibits the invasive ability of thyroid cancer cells by down-regulating the expression of VEGF-C in vitro.
Cell biochemistry and function 20120801
-
Low-dose rapamycin treatment increases the ability of human regulatory T cells to inhibit transplant arteriosclerosis in vivo.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120801
-
Connective tissue growth factor (CTGF/CCN2): a protagonist in cardiac allograft vasculopathy development?
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120801
-
The inhibitory effect of rapamycin on the oval cell response and development of preneoplastic foci in the rat.
Experimental and molecular pathology 20120801
-
Combined use of rapamycin and leflunomide in prevention of acute cardiac allografts rejection in rats.
Transplant immunology 20120801
-
Comparative assessment of transient exposure of paclitaxel or zotarolimus on in vitro vascular cell death, proliferation, migration, and proinflammatory biomarker expression.
Journal of cardiovascular pharmacology 20120801
-
Autophagy sustains the replication of porcine reproductive and respiratory virus in host cells.
Virology 20120801
-
Randomized phase II trial of everolimus in combination with tamoxifen in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer with prior exposure to aromatase inhibitors: a GINECO study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120801
-
Sirolimus modulates HIVAN phenotype through inhibition of epithelial mesenchymal transition.
Experimental and molecular pathology 20120801
-
Rapamycin slows aging in mice.
Aging cell 20120801
-
Immunosuppressive drugs on inducing Ag-specific CD4(+)CD25(+)Foxp3(+) Treg cells during immune response in vivo.
Transplant immunology 20120801
-
Stability of GABAB receptor oligomers revealed by dual TR-FRET and drug-induced cell surface targeting.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120801
-
Inhibition of the mTOR/S6K signal is necessary to enhance fluorouracil-induced apoptosis in gastric cancer cells with HER2 amplification.
International journal of oncology 20120801
-
Synergistic activity of the mTOR inhibitor ridaforolimus and the antiandrogen bicalutamide in prostate cancer models.
International journal of oncology 20120801
-
Sulforaphane, a cruciferous vegetable-derived isothiocyanate, inhibits protein synthesis in human prostate cancer cells.
Biochimica et biophysica acta 20120801
-
Monitoring autophagic flux by an improved tandem fluorescent-tagged LC3 (mTagRFP-mWasabi-LC3) reveals that high-dose rapamycin impairs autophagic flux in cancer cells.
Autophagy 20120801
-
Impact of oncogenic driver mutations on feedback between the PI3K and MEK pathways in cancer cells.
Bioscience reports 20120801
-
Combination of sorafenib and everolimus impacts therapeutically on adrenocortical tumor models.
Endocrine-related cancer 20120801
-
Prevention of age-related macular degeneration-like retinopathy by rapamycin in rats.
The American journal of pathology 20120801
-
Xience side branch access stent for treatment of bifurcation coronary disease: a review of preclinical data.
Journal of interventional cardiology 20120801
-
Phase I study of bevacizumab, everolimus, and panobinostat (LBH-589) in advanced solid tumors.
Cancer chemotherapy and pharmacology 20120801
-
TORC1 of fission yeast is rapamycin-sensitive.
Genes to cells : devoted to molecular & cellular mechanisms 20120801
-
Flow patterns at stented coronary bifurcations: computational fluid dynamics analysis.
Circulation. Cardiovascular interventions 20120801
-
Pregnancy in a kidney transplant patient treated with everolimus.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20120801
-
Non-clear cell renal cell carcinoma: does the mammalian target of rapamycin represent a rational therapeutic target?
The oncologist 20120801
-
Targeting angiogenesis in metastatic breast cancer.
The oncologist 20120801
-
The mTOR inhibitor everolimus in combination with carboplatin in metastatic breast cancer--a phase I trial.
Anticancer research 20120801
-
Brain metastasis in a patient with a sarcomatoid variant RCC with well-controlled extracerebral metastases by temsirolimus.
Anticancer research 20120801
-
[Soft-tissue sarcoma: recent developments].
Deutsche medizinische Wochenschrift (1946) 20120801
-
How to save Medicare: the anti-aging remedy.
Aging 20120801
-
Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian Target of Rapamycin Complex 1.
PLoS genetics 20120801
-
Paclitaxcel-coated balloon plus bare metal stent vs. sirolimus-eluting stent in de novo lesions: an IVUS study.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120801
-
In silico prediction for the investigation of comedication interferences in quantitative LC-MS detection in the SRM mode.
Bioanalysis 20120801
-
Stromal cell-derived factor 1α mediates resistance to mTOR-directed therapy in pancreatic cancer.
Neoplasia (New York, N.Y.) 20120801
-
Second-generation everolimus-eluting stents versus first-generation sirolimus-eluting stents in acute myocardial infarction. 1-year results of the randomized XAMI (XienceV Stent vs. Cypher Stent in Primary PCI for Acute Myocardial Infarction) trial.
Journal of the American College of Cardiology 20120731
-
Transient sequestration of TORC1 into stress granules during heat stress.
Molecular cell 20120727
-
Rapamycin attenuates aggressive behavior in a rat model of pilocarpine-induced epilepsy.
Neuroscience 20120726
-
Sirolimus and secondary skin-cancer prevention in kidney transplantation.
The New England journal of medicine 20120726
-
Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation.
Science translational medicine 20120725
-
Rapamycin reverses elevated mTORC1 signaling in lamin A/C-deficient mice, rescues cardiac and skeletal muscle function, and extends survival.
Science translational medicine 20120725
-
Multistage pH-responsive liposomes for mitochondrial-targeted anticancer drug delivery.
Advanced materials (Deerfield Beach, Fla.) 20120717
-
Protein translocation as a tool: The current rapamycin story.
FEBS letters 20120716
-
Preliminary experience with personalized and targeted therapy for pediatric brain tumors.
Pediatric blood & cancer 20120715
-
Mammalian target of rapamycin and the kidney. II. Pathophysiology and therapeutic implications.
American journal of physiology. Renal physiology 20120715
-
The differential effects of prenatal and/or postnatal rapamycin on neurodevelopmental defects and cognition in a neuroglial mouse model of tuberous sclerosis complex.
Human molecular genetics 20120715
-
Calcium/calmodulin-dependent protein kinase IV limits organ damage in hepatic ischemia-reperfusion injury through induction of autophagy.
American journal of physiology. Gastrointestinal and liver physiology 20120715
-
Novel agents and new combination treatments on phase I studies on solid tumors and pancreatic cancer.
JOP : Journal of the pancreas 20120710
-
Insulin stimulates IGFBP-2 expression in 3T3-L1 adipocytes through the PI3K/mTOR pathway.
Molecular and cellular endocrinology 20120706
-
Threonine-120 phosphorylation regulated by phosphoinositide-3-kinase/Akt and mammalian target of rapamycin pathway signaling limits the antitumor activity of mammalian sterile 20-like kinase 1.
The Journal of biological chemistry 20120706
-
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease.
Science translational medicine 20120704
-
TNFα-mediated apoptosis in human osteoarthritic chondrocytes sensitized by PI3K-NF-κB inhibitor, not mTOR inhibitor.
Rheumatology international 20120701
-
Impact of renal insufficiency on safety and efficacy of drug-eluting stents compared to bare-metal stents at 6 years.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120701
-
Everolimus is an active agent in medullary thyroid cancer: a clinical and in vitro study.
Journal of cellular and molecular medicine 20120701
-
Rapamycin affects tissue plasminogen activator and plasminogen activator inhibitor I expression: a potential prothrombotic mechanism of drug-eluting stents.
Angiology 20120701
-
Preliminary report of the use of everolimus in a patient with progressive medullary thyroid carcinoma.
Clinical endocrinology 20120701
-
Everolimus in combination with cyclosporin a as pre- and posttransplantation immunosuppressive therapy in nonmyeloablative allogeneic hematopoietic stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120701
-
Dasatinib synergizes with both cytotoxic and signal transduction inhibitors in heterogeneous breast cancer cell lines--lessons for design of combination targeted therapy.
Cancer letters 20120701
-
A multicenter phase II trial (SAKK 36/06) of single-agent everolimus (RAD001) in patients with relapsed or refractory mantle cell lymphoma.
Haematologica 20120701
-
Optimisation of the tumour response threshold in patients treated with everolimus for metastatic renal cell carcinoma: analysis of response and progression-free survival in the RECORD-1 study.
European journal of cancer (Oxford, England : 1990) 20120701
-
Different involvement of autophagy in human malignant glioma cell lines undergoing irradiation and temozolomide combined treatments.
Journal of cellular biochemistry 20120701
-
Low-dose sirolimus-eluting hydroxyapatite coating on stents does not increase platelet activation and adhesion ex vivo.
Journal of thrombosis and thrombolysis 20120701
-
Effects of the combination of RAD001 and docetaxel on breast cancer stem cells.
European journal of cancer (Oxford, England : 1990) 20120701
-
What do you do with the antiplatelet agents in patients with drug eluting stents who then receive a mechanical valve?
Interactive cardiovascular and thoracic surgery 20120701
-
Phase II study of sirolimus in treatment-naive patients with advanced hepatocellular carcinoma.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120701
-
Impact of routine angiographic follow-up after percutaneous coronary intervention with drug-eluting stents in the SPIRIT III randomized trial at three years.
The American journal of cardiology 20120701
-
Pneumonitis associated with mTOR inhibitors therapy in patients with metastatic renal cell carcinoma: incidence, radiographic findings and correlation with clinical outcome.
European journal of cancer (Oxford, England : 1990) 20120701
-
Five-year results of a randomized trial comparing de novo sirolimus and cyclosporine in renal transplantation: the SPIESSER study.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120701
-
Re: Camillo Porta, Emiliano Calvo, Miguel A. Climent, et al. Efficacy and safety of everolimus in elderly patients with metastatic renal cell carcinoma: an exploratory analysis of the outcomes of elderly patients in the RECORD-1 Trial. Eur Urol 2012;61:826-33.
European urology 20120701
-
A randomized, controlled study to assess the conversion from calcineurin-inhibitors to everolimus after liver transplantation--PROTECT.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120701
-
Functional analysis of the single Est1/Ebs1 homologue in Kluyveromyces lactis reveals roles in both telomere maintenance and rapamycin resistance.
Eukaryotic cell 20120701
-
Combination of an allosteric Akt Inhibitor MK-2206 with etoposide or rapamycin enhances the antitumor growth effect in neuroblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20120701
-
Simultaneous targeting of EGFR and mTOR inhibits the growth of colorectal carcinoma cells.
Oncology reports 20120701
-
Everolimus quantification in peripheral blood mononuclear cells using ultra high performance liquid chromatography tandem mass spectrometry.
Journal of pharmaceutical and biomedical analysis 20120701
-
Rapamycin and thrombosis.
Angiology 20120701
-
Inhibition of mammalian target of rapamycin reduces epileptogenesis and blood-brain barrier leakage but not microglia activation.
Epilepsia 20120701
-
Population pharmacokinetics and pharmacogenetics of everolimus in renal transplant patients.
Clinical pharmacokinetics 20120701
-
A phase I study of bevacizumab, everolimus and panitumumab in advanced solid tumors.
Cancer chemotherapy and pharmacology 20120701
-
A phase I study of temsirolimus plus carboplatin plus paclitaxel for patients with recurrent or metastatic (R/M) head and neck squamous cell cancer (HNSCC).
Cancer chemotherapy and pharmacology 20120701
-
The minimal impact of food on the pharmacokinetics of ridaforolimus.
Cancer chemotherapy and pharmacology 20120701
-
A study about drug combination therapy of Schisandra sphenanthera extract and Rapamycin in healthy subjects.
Canadian journal of physiology and pharmacology 20120701
-
Caveolin-1 and accelerated host aging in the breast tumor microenvironment: chemoprevention with rapamycin, an mTOR inhibitor and anti-aging drug.
The American journal of pathology 20120701
-
Everolimus: a challenging drug in the treatment of multifocal inoperable cardiac rhabdomyoma.
Pediatrics 20120701
-
Primary care management of tuberous sclerosis complex in children.
Journal of the American Academy of Nurse Practitioners 20120701
-
[Remission of an iatrogenic Kaposi sarcoma in a patient with myasthenia gravis after switching immunosuppressive therapy to the mTOR inhibitor everolimus].
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20120701
-
Implications of the new histological classification (WHO 2010) for pancreatic neuroendocrine neoplasms.
Annals of oncology : official journal of the European Society for Medical Oncology 20120701
-
Dimerizer-mediated regulation of gene expression.
Cold Spring Harbor protocols 20120701
-
Dimerizer-mediated regulation of gene expression in vitro.
Cold Spring Harbor protocols 20120701
-
Dimerizer-mediated regulation of gene expression in vivo.
Cold Spring Harbor protocols 20120701
-
Activation of the mTOR pathway in primary medullary thyroid carcinoma and lymph node metastases.
Clinical cancer research : an official journal of the American Association for Cancer Research 20120701
-
Efficacy of sequential treatment with sunitinib-everolimus in an orthotopic mouse model of renal cell carcinoma.
Anticancer research 20120701
-
14-3-3 protects against stress-induced apoptosis.
Cell death & disease 20120701
-
Sirolimus versus calcineurin inhibitor-based immunosuppressive therapy in kidney transplantation: a 4-year follow-up.
Iranian journal of kidney diseases 20120701
-
Symptomatic osteonecrosis of the femoral head after adult orthotopic liver transplantation.
Chinese medical journal 20120701
-
In vivo evaluation of the delivery and efficacy of a sirolimus-laden polymer gel for inhibition of hyperplasia in a porcine model of arteriovenous hemodialysis graft stenosis.
Journal of controlled release : official journal of the Controlled Release Society 20120628
-
Autophagy activation is associated with neuroprotection against apoptosis via a mitochondrial pathway in a rat model of subarachnoid hemorrhage.
Neuroscience 20120628
-
mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.
Nature 20120628
-
The PP242 mammalian target of rapamycin (mTOR) inhibitor activates extracellular signal-regulated kinase (ERK) in multiple myeloma cells via a target of rapamycin complex 1 (TORC1)/eukaryotic translation initiation factor 4E (eIF-4E)/RAF pathway and activation is a mechanism of resistance.
The Journal of biological chemistry 20120622
-
Inhibition of the mTORC2 and chaperone pathways to treat leukemia.
Blood 20120621
-
mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma.
Science translational medicine 20120620
-
The FKBP-rapamycin binding domain of human TOR undergoes strong conformational changes in the presence of membrane mimetics with and without the regulator phosphatidic acid.
Biochemistry 20120619
-
Selective ATP-competitive inhibitors of TOR suppress rapamycin-insensitive function of TORC2 in Saccharomyces cerevisiae.
ACS chemical biology 20120615
-
Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence.
Cell cycle (Georgetown, Tex.) 20120615
-
Suppression of replicative senescence by rapamycin in rodent embryonic cells.
Cell cycle (Georgetown, Tex.) 20120615
-
Review of cytomegalovirus infection findings with mammalian target of rapamycin inhibitor-based immunosuppressive therapy in de novo renal transplant recipients.
Transplantation 20120615
-
Identification and expansion of highly suppressive CD8(+)FoxP3(+) regulatory T cells after experimental allogeneic bone marrow transplantation.
Blood 20120614
-
Long-term clinical and angiographic outcome after treatment of chronic total occlusion with everolimus or sirolimus eluting stents.
International journal of cardiology 20120614
-
Short- and long-term outcomes with drug-eluting and bare-metal coronary stents: a mixed-treatment comparison analysis of 117 762 patient-years of follow-up from randomized trials.
Circulation 20120612
-
Lipopolysaccharide induction of autophagy is associated with enhanced bactericidal activity in Dictyostelium discoideum.
Biochemical and biophysical research communications 20120608
-
Further developments for improving response and tolerance to irradiation for advanced renal cancer: concurrent (mTOR) inhibitor RAD001 and helical tomotherapy.
Investigational new drugs 20120601
-
Everolimus-related organizing pneumonia: a report establishing causality.
Investigational new drugs 20120601
-
Temsirolimus in renal cell carcinoma with sarcomatoid differentiation: a report of three cases.
Medical oncology (Northwood, London, England) 20120601
-
p70 S6K1 nuclear localization depends on its mTOR-mediated phosphorylation at T389, but not on its kinase activity towards S6.
Amino acids 20120601
-
Combination or sequencing strategies to improve the outcome of metastatic renal cell carcinoma patients: a critical review.
Critical reviews in oncology/hematology 20120601
-
40-O -[2-Hydroxyethyl]rapamycin modulates human dendritic cell function during exposure to Aspergillus fumigatus.
Journal of basic microbiology 20120601
-
Alpha-ketoglutarate inhibits glutamine degradation and enhances protein synthesis in intestinal porcine epithelial cells.
Amino acids 20120601
-
Early treatment with everolimus exerts nephroprotective effect in rats with adriamycin-induced nephrotic syndrome.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120601
-
Primary anti-vascular endothelial growth factor (VEGF)-refractory metastatic renal cell carcinoma: clinical characteristics, risk factors, and subsequent therapy.
Annals of oncology : official journal of the European Society for Medical Oncology 20120601
-
Autophagy modulates osteoarthritis-related gene expression in human chondrocytes.
Arthritis and rheumatism 20120601
-
Rapamycin and a hyaluronic acid-carboxymethylcellulose membrane did not lead to reduced adhesion formations in a rat abdominal adhesion model.
Archives of gynecology and obstetrics 20120601
-
Interstitial pneumonitis is a frequent complication in liver transplant recipients treated with sirolimus.
Irish journal of medical science 20120601
-
Is there a role for targeted therapies in the collecting ducts of Bellini carcinoma? Efficacy data from a retrospective analysis of 7 cases.
Clinical and experimental nephrology 20120601
-
Impact of incomplete stent apposition on long-term clinical outcome after drug-eluting stent implantation.
European heart journal 20120601
-
Inhibition of neointimal hyperplasia with a novel zotarolimus coated balloon catheter.
Clinical research in cardiology : official journal of the German Cardiac Society 20120601
-
Hypothalamic mTOR pathway mediates thyroid hormone-induced hyperphagia in hyperthyroidism.
The Journal of pathology 20120601
-
Regulatory T cells exhibit decreased proliferation but enhanced suppression after pulsing with sirolimus.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120601
-
Inhibition of mammalian target of rapamycin signaling by CCI-779 (temsirolimus) induces growth inhibition and cell cycle arrest in Cashmere goat fetal fibroblasts (Capra hircus).
DNA and cell biology 20120601
-
Combination of Temsirolimus and tyrosine kinase inhibitors in renal carcinoma and endothelial cell lines.
Journal of cancer research and clinical oncology 20120601
-
Sirolimus protective effects on bone: the need to be demonstrated.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120601
-
Cyclosporine lowering with everolimus versus mycophenolate mofetil in heart transplant recipients: long-term follow-up of the SHIRAKISS randomized, prospective study.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120601
-
Mammalian target of rapamycin: a valid therapeutic target through the autophagy pathway for Alzheimer's disease?
Journal of neuroscience research 20120601
-
Post-transcriptional modulation of C/EBPα prompts monocytic differentiation and apoptosis in acute myelomonocytic leukaemia cells.
Leukemia research 20120601
-
Modulation of mTOR effector phosphoproteins in blood basophils from allergic patients.
Journal of clinical immunology 20120601
-
System for integrated adherence monitoring: real-time non-adherence risk assessment in pediatric kidney transplantation.
Pediatric transplantation 20120601
-
Modulation of sodium iodide symporter expression and function by LY294002, Akti-1/2 and Rapamycin in thyroid cells.
Endocrine-related cancer 20120601
-
A single-dose placebo- and moxifloxacin-controlled study of the effects of temsirolimus on cardiac repolarization in healthy adults.
Cancer chemotherapy and pharmacology 20120601
-
Immunophyllin ligands show differential effects on alcohol self-administration in C57BL mice.
The Journal of pharmacology and experimental therapeutics 20120601
-
Ghrelin contributes to derangements of glucose metabolism induced by rapamycin in mice.
Diabetologia 20120601
-
Gli inhibitor GANT61 causes apoptosis in myeloid leukemia cells and acts in synergy with rapamycin.
Leukemia research 20120601
-
The role of mTOR inhibitors in the inhibition of growth and cortisol secretion in human adrenocortical carcinoma cells.
Endocrine-related cancer 20120601
-
A novel library screen identifies immunosuppressors that promote osteoblast differentiation.
Bone 20120601
-
Everolimus-eluting versus sirolimus-eluting stents: an updated meta-analysis of randomized trials.
Clinical research in cardiology : official journal of the German Cardiac Society 20120601
-
Influence of diabetes mellitus on long-term (five-year) outcomes of drug-eluting stents and coronary artery bypass grafting for multivessel coronary revascularization.
The American journal of cardiology 20120601
-
Pancreatic neuroendocrine and carcinoid tumors: what's new, what's old, and what's different?
Current oncology reports 20120601
-
Effect of everolimus on pre-existing atherosclerosis in LDL-receptor deficient mice.
Atherosclerosis 20120601
-
Measuring adherence to medications: are complex methods superior to simple ones?
Pediatric transplantation 20120601
-
Inhibition of mTORC1 kinase activates Smads 1 and 5 but not Smad8 in human prostate cancer cells, mediating cytostatic response to rapamycin.
Molecular cancer research : MCR 20120601
-
Subconjunctival sirolimus for the treatment of chronic active anterior uveitis: results of a pilot trial.
American journal of ophthalmology 20120601
-
Major involvement of mTOR in the PPARγ-induced stimulation of adipose tissue lipid uptake and fat accretion.
Journal of lipid research 20120601
-
Luteinizing hormone facilitates angiogenesis in ovarian epithelial tumor cells and metformin inhibits the effect through the mTOR signaling pathway.
Oncology reports 20120601
-
The impact of sirolimus on sex hormones in male adolescent kidney recipients.
Pediatric transplantation 20120601
-
Increase in cholesterol predicts survival advantage in renal cell carcinoma patients treated with temsirolimus.
Clinical cancer research : an official journal of the American Association for Cancer Research 20120601
-
Immunosuppressive regimen and interstitial fibrosis and tubules atrophy at 12 months postrenal transplant.
Clinical journal of the American Society of Nephrology : CJASN 20120601
-
Combination of Rad001 (everolimus) and propachlor synergistically induces apoptosis through enhanced autophagy in prostate cancer cells.
Molecular cancer therapeutics 20120601
-
A role of the mammalian target of rapamycin (mTOR) in glutamate-induced down-regulation of tuberous sclerosis complex proteins 2 (TSC2).
Journal of molecular neuroscience : MN 20120601
-
Endothelial-dependent vasomotion in a coronary segment treated by ABSORB everolimus-eluting bioresorbable vascular scaffold system is related to plaque composition at the time of bioresorption of the polymer: indirect finding of vascular reparative therapy?
European heart journal 20120601
-
Serum cholesterol and mTOR inhibitors: surrogate biomarker or epiphenomenon?
Clinical cancer research : an official journal of the American Association for Cancer Research 20120601
-
Circulating biomarkers of response to sunitinib in gastroenteropancreatic neuroendocrine tumors: current data and clinical outlook.
Molecular diagnosis & therapy 20120601
-
Cordycepin as a sensitizer to tumour necrosis factor (TNF)-α-induced apoptosis through eukaryotic translation initiation factor 2α (eIF2α)- and mammalian target of rapamycin complex 1 (mTORC1)-mediated inhibition of nuclear factor (NF)-κB.
Clinical and experimental immunology 20120601
-
Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response.
Biochimica et biophysica acta 20120601
-
Results of a phase II study of sirolimus and cyclophosphamide in patients with advanced sarcoma.
European journal of cancer (Oxford, England : 1990) 20120601
-
Effect of sirolimus on the regression of peritoneal sclerosis in an experimental rat model.
International urology and nephrology 20120601
-
Histopathological comparison of biodegradable polymer and permanent polymer based sirolimus eluting stents in a porcine model of coronary stent implantation.
Thrombosis and haemostasis 20120601
-
Radiosensitization of renal cell carcinoma in vitro through the induction of autophagy.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20120601
-
A further step towards vascular reparative therapy.
European heart journal 20120601
-
SIRT1 is required for the effects of rapamycin on high glucose-inducing mesangial cells senescence.
Mechanisms of ageing and development 20120601
-
Autophagy and cardiovascular aging: lesson learned from rapamycin.
Cell cycle (Georgetown, Tex.) 20120601
-
New targeted agents in gastroenteropancreatic neuroendocrine tumors.
Targeted oncology 20120601
-
Everolimus in different combinations as maintenance immunosuppressive therapy in heart transplant recipients.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120601
-
Everolimus-induced lymphedema in a renal transplant recipient: a case report.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120601
-
Conversion from cyclosporine to everolimus at 4.5 months posttransplant: 3-year results from the randomized ZEUS study.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120601
-
[Renal carcinoma: point on treatment of brain metastasis].
Bulletin du cancer 20120601
-
Peritoneovenous shunt for chylous ascites after lung transplantation for lymphangioleiomyomatosis.
Transplantation proceedings 20120601
-
Gender differences in patients treated with the zotarolimus-eluting stent at a tertiary medical center.
The Journal of invasive cardiology 20120601
-
Targeting mTOR in mantle cell lymphoma: current and future directions.
Best practice & research. Clinical haematology 20120601
-
Malignant perivascular epithelioid cell tumor in children: description of a case and review of the literature.
Journal of pediatric surgery 20120601
-
Lymphedema of the breast as a symptom of internal diseases or side effect of mTor inhibitors.
Lymphatic research and biology 20120601
-
Contemporary incidence and predictors of stent thrombosis and other major adverse cardiac events in the year after XIENCE V implantation: results from the 8,061-patient XIENCE V United States study.
JACC. Cardiovascular interventions 20120601
-
The role of autophagy during coxsackievirus infection of neural progenitor and stem cells.
Autophagy 20120601
-
Dissecting mammalian target of rapamycin to promote longevity.
Rejuvenation research 20120601
-
The BOLERO-2 trial: the addition of everolimus to exemestane in the treatment of postmenopausal hormone receptor-positive advanced breast cancer.
Future oncology (London, England) 20120601
-
Medium to long-term clinical outcomes with everolimus-eluting stents in real-life percutaneous coronary intervention.
Annals of the Academy of Medicine, Singapore 20120601
-
Proteinuria following sirolimus conversion is associated with deterioration of kidney function in liver transplant recipients.
Transplantation 20120527
-
Evaluation of the peri-strut low intensity area following sirolimus- and paclitaxel-eluting stents implantation: insights from an optical coherence tomography study in humans.
International journal of cardiology 20120517
-
Clinical performance of a drug-eluting stent with a biodegradable polymer in an unselected patient population: the NOBORI 2 study.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120515
-
mTOR inhibition with rapamycin causes impaired insulin signalling and glucose uptake in human subcutaneous and omental adipocytes.
Molecular and cellular endocrinology 20120515
-
Sirolimus-associated testicular toxicity: detrimental but reversible.
Transplantation 20120515
-
Impact of statin therapy on late target lesion revascularization after sirolimus-eluting stent implantation (from the CREDO-Kyoto Registry Cohort-2).
The American journal of cardiology 20120515
-
Radiochemical high-performance liquid chromatography detection of arginine metabolism in human endothelial cells.
Analytical biochemistry 20120515
-
Stable isotope-labelling analysis of the impact of inhibition of the mammalian target of rapamycin on protein synthesis.
The Biochemical journal 20120515
-
Impact of age on clinical outcomes after everolimus-eluting and paclitaxel-eluting stent implantation: pooled analysis from the SPIRIT III and SPIRIT IV clinical trials.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120515
-
Late clinical outcomes after implantation of drug-eluting stents coated with biodegradable polymers: 3-year follow-up of the PAINT randomised trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120515
-
Inhibition of influenza A virus replication by antagonism of a PI3K-AKT-mTOR pathway member identified by gene-trap insertional mutagenesis.
Antiviral chemistry & chemotherapy 20120514
-
Use of sirolimus in patients with primary steroid-resistant nephrotic syndrome.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20120514
-
Reduction of Na/K-ATPase potentiates marinobufagenin-induced cardiac dysfunction and myocyte apoptosis.
The Journal of biological chemistry 20120511
-
A perivascular system releasing sirolimus prevented intimal hyperplasia in a rabbit model in a medium-term study.
International journal of pharmaceutics 20120510
-
Regulation of the glutamate transporter EAAT3 by mammalian target of rapamycin mTOR.
Biochemical and biophysical research communications 20120504
-
Flat panel digital detector cinefluoroscopy late following SES or BMS implantation for detection of coronary stent fracture in asymptomatic patients.
International journal of cardiology 20120503
-
Everolimus in HR-positive advanced breast cancer.
The New England journal of medicine 20120503
-
Everolimus in HR-positive advanced breast cancer.
The New England journal of medicine 20120503
-
TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO.
Cell metabolism 20120502
-
Agreement and reproducibility of gray-scale intravascular ultrasound and optical coherence tomography for the analysis of the bioresorbable vascular scaffold.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501
-
Seven-year safety and efficacy of the unrestricted use of drug-eluting stents in saphenous vein bypass grafts.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501
-
Combination testing (Stage 2) of the Anti-IGF-1 receptor antibody IMC-A12 with rapamycin by the pediatric preclinical testing program.
Pediatric blood & cancer 20120501
-
Successful coronary intervention of chronic total occlusion of the right coronary artery by ipsilateral injection via an isolated conus artery.
Heart and vessels 20120501
-
A phase 1 study of weekly everolimus (RAD001) in combination with docetaxel in patients with metastatic breast cancer.
Cancer 20120501
-
Suppression of neointimal hyperplasia by sirolimus-eluting expanded polytetrafluoroethylene (ePTFE) haemodialysis grafts in comparison with paclitaxel-coated grafts.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120501
-
Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity.
Journal of molecular medicine (Berlin, Germany) 20120501
-
Repeat-dose sirolimus pharmacokinetics and pharmacodynamics in patients with hepatic allografts.
European journal of clinical pharmacology 20120501
-
The union of anti-CD34 antibody can improve the performance of drug-eluting stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501
-
Upregulation of mTORC2 activation by the selective agonist of EPAC, 8-CPT-2Me-cAMP, in prostate cancer cells: assembly of a multiprotein signaling complex.
Journal of cellular biochemistry 20120501
-
Molecular characterization and functional analysis of Cashmere goat mammalian target of rapamycin.
DNA and cell biology 20120501
-
Magnetic stents retain nanoparticle-bound antirestenotic drugs transported by lipid microbubbles.
Pharmaceutical research 20120501
-
Assay validation of phosphorylated S6 ribosomal protein for a pharmacodynamic monitoring of mTOR-inhibitors in peripheral human blood.
Cytometry. Part B, Clinical cytometry 20120501
-
Analysis of the pharmacodynamic activity of the mTOR inhibitor ridaforolimus (AP23573, MK-8669) in a phase 1 clinical trial.
Cancer chemotherapy and pharmacology 20120501
-
Sorafenib for recurrence of hepatocellular carcinoma after liver transplantation.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120501
-
Preparation and optimization of media using Pluronic® micelles for solubilization of sirolimus and release from the drug eluting stents.
Colloids and surfaces. B, Biointerfaces 20120501
-
V-AKT murine thymoma viral oncogene homolog/mammalian target of rapamycin activation induces a module of metabolic changes contributing to growth in insulin-induced hepatocarcinogenesis.
Hepatology (Baltimore, Md.) 20120501
-
Sustained antitumor activity by co-targeting mTOR and the microtubule with temsirolimus/vinblastine combination in hepatocellular carcinoma.
Biochemical pharmacology 20120501
-
The effect of multiple doses of rifampin and ketoconazole on the single-dose pharmacokinetics of ridaforolimus.
Cancer chemotherapy and pharmacology 20120501
-
Everolimus exhibits efficacy as a radiosensitizer in a model of non-small cell lung cancer.
Oncology reports 20120501
-
Impact of sirolimus duration on hepatitis C related fibrosis progression in liver transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120501
-
An indirect comparison of everolimus versus sorafenib in metastatic renal cell carcinoma - a flawed analysis?
Expert opinion on pharmacotherapy 20120501
-
Donor-specific HLA antibodies in a cohort comparing everolimus with cyclosporine after kidney transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120501
-
Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2).
Diabetologia 20120501
-
Akt inhibitors MK-2206 and nelfinavir overcome mTOR inhibitor resistance in diffuse large B-cell lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20120501
-
Safety and efficacy of the XIENCE V everolimus-eluting stent compared to first-generation drug-eluting stents in contemporary clinical practice.
The American journal of cardiology 20120501
-
Dose-dependent effects of sirolimus on mTOR signaling and polycystic kidney disease.
Journal of the American Society of Nephrology : JASN 20120501
-
Everolimus triggers cytokine release by macrophages: rationale for stents eluting everolimus and a glucocorticoid.
Arteriosclerosis, thrombosis, and vascular biology 20120501
-
Systemic rapamycin alone may not be a treatment option for malignant glioma: evidence from an in vivo study.
Journal of neuro-oncology 20120501
-
Acute depletion of plasma membrane phosphatidylinositol 4,5-bisphosphate impairs specific steps in endocytosis of the G-protein-coupled receptor.
Journal of cell science 20120501
-
Treatment of congenital tracheal stenosis by balloon-expandable metallic stents in paediatric intensive care unit.
Interactive cardiovascular and thoracic surgery 20120501
-
Autophagy proteins play cytoprotective and cytocidal roles in leucine starvation-induced cell death in Saccharomyces cerevisiae.
Autophagy 20120501
-
Effects of rapamycin-induced oligomerization of parvalbumin, Stim1 and Orai1 in puncta formation.
Cell calcium 20120501
-
The impact of sirolimus on sex hormones in male adolescent kidney recipients.
Pediatric transplantation 20120501
-
Prolonged survival of allogeneic islets in cynomolgus monkeys after short-term triple therapy.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120501
-
Cavitatory lung disease in thoracic transplant recipients receiving sirolimus.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120501
-
mTOR is required for asymmetric division through small GTPases in mouse oocytes.
Molecular reproduction and development 20120501
-
mTOR as a molecular target in HPV-associated oral and cervical squamous carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 20120501
-
Randomized controlled trial of sirolimus for renal transplant recipients at high risk for nonmelanoma skin cancer.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120501
-
Regulation of mTOR complex 2 signaling in neurofibromatosis 2-deficient target cell types.
Molecular cancer research : MCR 20120501
-
Patterns of interstitial lung disease during everolimus treatment in patients with metastatic renal cell carcinoma.
Japanese journal of clinical oncology 20120501
-
Limus is not limus--a proposal to adjust terminology in the context of drug-eluting stents.
Journal of cardiovascular pharmacology 20120501
-
Biodegradable polymer drug-eluting stents reduce the risk of stent thrombosis at 4 years in patients undergoing percutaneous coronary intervention: a pooled analysis of individual patient data from the ISAR-TEST 3, ISAR-TEST 4, and LEADERS randomized trials.
European heart journal 20120501
-
Inhibition of mammalian target of rapamycin augments lipopolysaccharide-induced lung injury and apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 20120501
-
Insulin growth factor-receptor (IGF-1R) antibody cixutumumab combined with the mTOR inhibitor temsirolimus in patients with refractory Ewing's sarcoma family tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 20120501
-
Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice.
The Journal of clinical investigation 20120501
-
Cyclosporin but not everolimus inhibits chemokine receptor expression on CD4+ T cell subsets circulating in the peripheral blood of renal transplant recipients.
Clinical and experimental immunology 20120501
-
Everolimus plus early tacrolimus minimization: a phase III, randomized, open-label, multicentre trial in renal transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20120501
-
Possible correlation of sirolimus plasma concentration with sinusoidal obstructive syndrome of the liver in patients undergoing myeloablative allogeneic hematopoietic cell transplantation.
Pharmacotherapy 20120501
-
A brain aggregate model gives new insights into the pathobiology and treatment of prion diseases.
Journal of neuropathology and experimental neurology 20120501
-
Objective versus subjective guidance of (bioabsorbable) stent implantation: the saga continues.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501
-
Proximal and distal maximal luminal diameters as a guide to appropriate deployment of the ABSORB everolimus-eluting bioresorbable vascular scaffold: a sub-study of the ABSORB Cohort B and the on-going ABSORB EXTEND Single Arm Study.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501
-
Emerging treatments in the management of tuberous sclerosis complex.
Pediatric neurology 20120501
-
mTOR inhibitors: a myth, a cure for cancer or something in between?
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120501
-
Comment on 'Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells' Haematologica 2011;96(9):1357-65.
Haematologica 20120501
-
Cardiac allograft vasculopathy compared by intravascular ultrasound sonography: everolimus to mycophenolate mofetil--one single-center experience.
Transplantation proceedings 20120501
-
Clinical experience of tacrolimus with everolimus in heart transplantation.
Transplantation proceedings 20120501
-
Metformin and the mTOR inhibitor everolimus (RAD001) sensitize breast cancer cells to the cytotoxic effect of chemotherapeutic drugs in vitro.
Anticancer research 20120501
-
The SPIRIT V diabetic study: a randomized clinical evaluation of the XIENCE V everolimus-eluting stent vs the TAXUS Liberté paclitaxel-eluting stent in diabetic patients with de novo coronary artery lesions.
American heart journal 20120501
-
Long-term clinical and angiographic outcomes of diabetic patients after revascularization with early generation drug-eluting stents.
American heart journal 20120501
-
The impact of preprocedural hemoglobin A1c on the efficacy of sirolimus-eluting and paclitaxel-eluting stents.
Cardiovascular intervention and therapeutics 20120501
-
Stability of ready-to-use temsirolimus infusion solution (100mg/L) in polypropylene containers under different storage conditions.
Annales pharmaceutiques francaises 20120501
-
Systemic exposure of sirolimus after coronary stent implantation in patients with de novo coronary lesions: Supralimus-Core® pharmacokinetic study.
Indian heart journal 20120501
-
Once again on rapamycin-induced insulin resistance and longevity: despite of or owing to.
Aging 20120501
-
[Progress and extensive meaning of mammalian target of rapamycin involved in restoration of nervous system injury].
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20120501
-
Brief report: a phase II 'window-of-opportunity' frontline study of the MTOR inhibitor, temsirolimus given as a single agent in patients with advanced NSCLC, an NCCTG study.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20120501
-
Late subcapsular lymphocele in a kidney graft.
Transplantation 20120427
-
The pan-deacetylase inhibitor panobinostat induces cell death and synergizes with everolimus in Hodgkin lymphoma cell lines.
Blood 20120426
-
Regulation of presynaptic neurotransmission by macroautophagy.
Neuron 20120426
-
Short- versus long-term duration of dual-antiplatelet therapy after coronary stenting: a randomized multicenter trial.
Circulation 20120424
-
Everolimus in metastatic renal cell carcinoma patients intolerant to previous VEGFr-TKI therapy: a RECORD-1 subgroup analysis.
British journal of cancer 20120424
-
Drug-eluting vs bare-metal stents in primary angioplasty: a pooled patient-level meta-analysis of randomized trials.
Archives of internal medicine 20120423
-
Effect of persistent activation of phosphoinositide 3-kinase on heart.
Life sciences 20120420
-
PI3-kinase and mTOR inhibitors differently modulate the function of the ABCG2 multidrug transporter.
Biochemical and biophysical research communications 20120420
-
Surface crystallization of rapamycin on stents using a temperature induced process.
Langmuir : the ACS journal of surfaces and colloids 20120417
-
Rapamycin with antiretroviral therapy in AIDS-associated Kaposi sarcoma: an AIDS Malignancy Consortium study.
Journal of acquired immune deficiency syndromes (1999) 20120415
-
Murine islet allograft tolerance upon blockade of the B-lymphocyte stimulator, BLyS/BAFF.
Transplantation 20120415
-
Blocking mTORC1 activity by rapamycin leads to impairment of spatial memory retrieval but not acquisition in C57BL/6J mice.
Behavioural brain research 20120415
-
Production of interferon α by human immunodeficiency virus type 1 in human plasmacytoid dendritic cells is dependent on induction of autophagy.
The Journal of infectious diseases 20120415
-
The struggle for energy in podocytes leads to nephrotic syndrome.
Cell cycle (Georgetown, Tex.) 20120415
-
Stent thrombosis with drug-eluting and bare-metal stents: evidence from a comprehensive network meta-analysis.
Lancet (London, England) 20120414
-
Controlled release formulations of IL-2, TGF-β1 and rapamycin for the induction of regulatory T cells.
Journal of controlled release : official journal of the Controlled Release Society 20120410
-
Primary endpoint results of the EVOLVE trial: a randomized evaluation of a novel bioabsorbable polymer-coated, everolimus-eluting coronary stent.
Journal of the American College of Cardiology 20120410
-
A randomized controlled trial in second-generation zotarolimus-eluting Resolute stents versus everolimus-eluting Xience V stents in real-world patients: the TWENTE trial.
Journal of the American College of Cardiology 20120410
-
Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells.
The Journal of biological chemistry 20120406
-
Des-acyl ghrelin exhibits pro-anabolic and anti-catabolic effects on C2C12 myotubes exposed to cytokines and reduces burn-induced muscle proteolysis in rats.
Molecular and cellular endocrinology 20120404
-
Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling.
Cell metabolism 20120404
-
Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice.
The Journal of clinical investigation 20120402
-
A phase I study of temsirolimus and metformin in advanced solid tumours.
Investigational new drugs 20120401
-
Combination testing of cediranib (AZD2171) against childhood cancer models by the pediatric preclinical testing program.
Pediatric blood & cancer 20120401
-
Sirolimus and mycophenolate mofetil as GVHD prophylaxis in myeloablative, matched-related donor hematopoietic cell transplantation.
Bone marrow transplantation 20120401
-
Major determinants for the uncovered stent struts on optical coherence tomography after drug-eluting stent implantation.
The international journal of cardiovascular imaging 20120401
-
Optical coherence tomography findings of very late stent thrombosis after drug-eluting stent implantation.
The international journal of cardiovascular imaging 20120401
-
Combination of targeted agents in metastatic renal cell carcinoma: a path forward or a dead-end street?
Cancer 20120401
-
Phase 1 trial of everolimus plus sunitinib in patients with metastatic renal cell carcinoma.
Cancer 20120401
-
Chronic mTOR inhibition by rapamycin induces muscle insulin resistance despite weight loss in rats.
British journal of pharmacology 20120401
-
Krüppel-like factor 4 is induced by rapamycin and mediates the anti-proliferative effect of rapamycin in rat carotid arteries after balloon injury.
British journal of pharmacology 20120401
-
Mechanical injury suppresses autophagy regulators and pharmacologic activation of autophagy results in chondroprotection.
Arthritis and rheumatism 20120401
-
Ridaforolimus for patients with progressive or recurrent malignant glioma: a perisurgical, sequential, ascending-dose trial.
Cancer chemotherapy and pharmacology 20120401
-
Dynamic contrast-enhanced micro-CT on mice with mammary carcinoma for the assessment of antiangiogenic therapy response.
European radiology 20120401
-
Autophagy activation by rapamycin reduces severity of experimental osteoarthritis.
Annals of the rheumatic diseases 20120401
-
Morphological and degradation studies of sirolimus-containing poly(lactide-co-glycolide) discs.
Journal of biomedical materials research. Part B, Applied biomaterials 20120401
-
Molecular targeted agents for gastric and gastroesophageal junction cancer.
Surgery today 20120401
-
Phase I study for ridaforolimus, an oral mTOR inhibitor, in Japanese patients with advanced solid tumors.
Cancer chemotherapy and pharmacology 20120401
-
Identification of a novel biomarker gene set with sensitivity and specificity for distinguishing between allograft rejection and tolerance.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120401
-
Combined mTOR inhibition and OX40 agonism enhances CD8(+) T cell memory and protective immunity produced by recombinant adenovirus vaccines.
Molecular therapy : the journal of the American Society of Gene Therapy 20120401
-
Regulatory T cells expanded by rapamycin in vitro suppress colitis in an experimental mouse model.
Journal of gastroenterology 20120401
-
Immunosuppressive drug rapamycin restores sporulation competence in industrial yeasts.
Journal of bioscience and bioengineering 20120401
-
Pharmacologic inhibition of mTOR antagonizes the cytotoxic activity of pemetrexed in non-small cell lung cancer.
Journal of cancer research and clinical oncology 20120401
-
Regulation of physiologic actions of LRRK2: focus on autophagy.
Neuro-degenerative diseases 20120401
-
Autophagy is a cell death mechanism in Toxoplasma gondii.
Cellular microbiology 20120401
-
Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling.
Aging cell 20120401
-
Meta-analysis of long-term outcomes for drug-eluting stents versus bare-metal stents in primary percutaneous coronary interventions for ST-segment elevation myocardial infarction.
The American journal of cardiology 20120401
-
TOR signaling is involved in PTTH-stimulated ecdysteroidogenesis by prothoracic glands in the silkworm, Bombyx mori.
Insect biochemistry and molecular biology 20120401
-
Development of a combination drug-eluting bead: towards enhanced efficacy for locoregional tumour therapies.
Anti-cancer drugs 20120401
-
Determination of everolimus in blood samples from kidney and liver transplant recipients using the sirolimus chemiluminescence magnetic microparticle immunoassay (CMIA) on the Architect-i1000® system.
Scandinavian journal of clinical and laboratory investigation 20120401
-
Adhesion and cohesion in structures containing suspended microscopic polymeric films.
Acta biomaterialia 20120401
-
Radical reduction of smooth muscle cells in explanted lung of a LAM patient treated with sirolimus: first case report.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120401
-
Everolimus-eluting stents and paclitaxel-eluting stents in patients presenting with myocardial infarction: insights from the two-year results of the COMPARE prospective randomised controlled trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401
-
Potential of T-regulatory cells to protect xenografts.
Current opinion in organ transplantation 20120401
-
Induced regulatory T cells: mechanisms of conversion and suppressive potential.
Human immunology 20120401
-
Efficacy and safety of everolimus in elderly patients with metastatic renal cell carcinoma: an exploratory analysis of the outcomes of elderly patients in the RECORD-1 Trial.
European urology 20120401
-
TORC2 signaling is antagonized by protein phosphatase 2A and the Far complex in Saccharomyces cerevisiae.
Genetics 20120401
-
Role of rapamycin-induced autophagy in pancreatic islets.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120401
-
Comparison of biolimus eluted from an erodible stent coating with bare metal stents in acute ST-elevation myocardial infarction (COMFORTABLE AMI trial): rationale and design.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401
-
Rapamycin resistance is linked to defective regulation of Skp2.
Cancer research 20120401
-
Immunological advantages of everolimus versus cyclosporin A in liver-transplanted recipients, as revealed by polychromatic flow cytometry.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20120401
-
Early conversion to a sirolimus-based, calcineurin-inhibitor-free immunosuppression in the SMART trial: observational results at 24 and 36months after transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20120401
-
Analytical performance of a new liquid chromatography/tandem mass spectrometric method for determination of everolimus concentrations in whole blood.
Therapeutic drug monitoring 20120401
-
New strategies for advanced neuroendocrine tumors in the era of targeted therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 20120401
-
Effects of an agonist interleukin-2/Fc fusion protein, a mutant antagonist interleukin-15/Fc fusion protein, and sirolimus on cardiac allograft survival in non-human primates.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120401
-
Regulating mammalian target of rapamycin to tune vaccination-induced CD8(+) T cell responses for tumor immunity.
Journal of immunology (Baltimore, Md. : 1950) 20120401
-
Blue rubber bleb nevus syndrome: successful treatment with sirolimus.
Pediatrics 20120401
-
Comparison of 5-year clinical outcomes between sirolimus-versus paclitaxel-eluting stent: Korean multicenter network analysis of 9000-patient cohort.
Circulation. Cardiovascular interventions 20120401
-
Everolimus: preventing organ rejection in adult kidney transplant recipients.
Expert opinion on pharmacotherapy 20120401
-
Impact of stenting and oral sirolimus on endothelium-dependent and independent coronary vasomotion.
Arquivos brasileiros de cardiologia 20120401
-
Long-term results of conversion from calcineurin inhibitors to sirolimus in 150 maintenance kidney transplant patients.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120401
-
Sirolimus conversion in liver transplant recipients with calcineurin inhibitor-induced complications: efficacy and safety.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120401
-
Periprocedural myocardial infarction in a randomized trial of everolimus-eluting and Paclitaxel-eluting coronary stents: frequency and impact on mortality according to historic versus universal definitions.
Circulation. Cardiovascular interventions 20120401
-
Targeting autophagy for drug-induced hepatotoxicity.
Autophagy 20120401
-
Everolimus: targeted therapy on the horizon for the treatment of breast cancer.
Pharmacotherapy 20120401
-
Autophagy: a new therapeutic target in cartilage injury and osteoarthritis.
The Journal of the American Academy of Orthopaedic Surgeons 20120401
-
Acute ST-elevation myocardial infarction 6 years following a sirolimus-eluting stent secondary to complete stent fracture.
The Journal of invasive cardiology 20120401
-
Successful sealing of a coronary artery perforation with a mesh-covered stent.
The Journal of invasive cardiology 20120401
-
The 4-week serum creatinine level predicts long-term renal dysfunction after adult living donor liver transplantation.
Transplantation proceedings 20120401
-
Rapamycin combined with allogenic immature dendritic cells selectively expands CD4+CD25+Foxp3+ regulatory T cells in rats.
Hepatobiliary & pancreatic diseases international : HBPD INT 20120401
-
Suppression of autophagy is protective in high glucose-induced cardiomyocyte injury.
Autophagy 20120401
-
Breakthroughs in myeloproliferative neoplasms.
Hematology (Amsterdam, Netherlands) 20120401
-
mTOR-dependent modulation of gastric nesfatin-1/NUCB2.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120401
-
The prequel: defining prognostically important criteria in the periprocedural PCI troponin saga.
Circulation. Cardiovascular interventions 20120401
-
Magnetic nanoparticles and rapamycin encapsulated into polymeric nanocarriers.
Journal of biomedical nanotechnology 20120401
-
Differences in neointimal thickness between the adluminal and the abluminal sides of malapposed and side-branch struts in a polylactide bioresorbable scaffold: evidence in vivo about the abluminal healing process.
JACC. Cardiovascular interventions 20120401
-
Nobori stent shows less vascular inflammation and early recovery of endothelial function compared with Cypher stent.
JACC. Cardiovascular interventions 20120401
-
DUrable polymer-based sTent CHallenge of Promus ElemEnt versus ReSolute integrity (DUTCH PEERS): rationale and study design of a randomized multicenter trial in a Dutch all-comers population.
American heart journal 20120401
-
ComparisOn of neointimal coVerage betwEen zotaRolimus-eluting stent and everolimus-eluting stent using Optical Coherence Tomography (COVER OCT).
American heart journal 20120401
-
Optical coherence tomography (OCT) evaluation after coronary stenting: the 'black hole' and other low OCT signal-intensity areas.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401
-
Atypical 'black hole' phenomenon after treatment of sirolimus stent restenosis with a paclitaxel-coated balloon.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401
-
Serial optical coherence tomography imaging of the 'black-hole' phenomenon by intravascular ultrasound following sirolimus-eluting stent implantation.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401
-
Targeted therapeutics in treatment of children and young adults with solid tumors: an expert survey and review of the literature.
Klinische Padiatrie 20120401
-
Rapamycin increases oxidative stress response gene expression in adult stem cells.
Aging 20120401
-
Plasmonic photothermic and stem cell therapy of atherosclerotic plaque as a novel nanotool for angioplasty and artery remodeling.
Rejuvenation research 20120401
-
[Effect of rapamycin on high glucose-induced autophagy impairment, oxidative stress and premature senescence in rat mesangial cells in vitro].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120401
-
Drug-eluting vs. bare metal stents for symptomatic vertebral artery stenosis.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20120401
-
[Rapamycin inhibits the proliferation of prostate cancer cell line 22RV1 and activity of S6K1].
Zhonghua nan ke xue = National journal of andrology 20120401
-
Phase II study of concurrent radiation therapy, temozolomide, and bevacizumab followed by bevacizumab/everolimus as first-line treatment for patients with glioblastoma.
Clinical advances in hematology & oncology : H&O 20120401
-
TOR signaling regulates ribosome and tRNA synthesis via LAMMER/Clk and GSK-3 family kinases.
Molecular cell 20120330
-
Rapamycin suppresses the recurrent excitatory circuits of dentate gyrus in a mouse model of temporal lobe epilepsy.
Biochemical and biophysical research communications 20120330
-
The TOR complex 1 is a direct target of Rho1 GTPase.
Molecular cell 20120330
-
Cell biology. Rapamycin paradox resolved.
Science (New York, N.Y.) 20120330
-
Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity.
Science (New York, N.Y.) 20120330
-
Chronic activation of mTOR complex 1 is sufficient to cause hepatocellular carcinoma in mice.
Science signaling 20120327
-
Hyperplexing: a method for higher-order multiplexed quantitative proteomics provides a map of the dynamic response to rapamycin in yeast.
Science signaling 20120327
-
Rapid and orthogonal logic gating with a gibberellin-induced dimerization system.
Nature chemical biology 20120325
-
Transcription factor Foxo1 represses T-bet-mediated effector functions and promotes memory CD8(+) T cell differentiation.
Immunity 20120323
-
Rapamycin promotes autophagy and reduces neural tissue damage and locomotor impairment after spinal cord injury in mice.
Journal of neurotrauma 20120320
-
Randomized trial of optimal treatment strategies for in-stent restenosis after drug-eluting stent implantation.
Journal of the American College of Cardiology 20120320
-
Rapamycin enhances docetaxel-induced cytotoxicity in a androgen-independent prostate cancer xenograft model by survivin downregulation.
Biochemical and biophysical research communications 20120316
-
Single-cell pharmacodynamic monitoring of S6 ribosomal protein phosphorylation in AML blasts during a clinical trial combining the mTOR inhibitor sirolimus and intensive chemotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 20120315
-
Innate and adaptive immune responses are tolerized in chimeras prepared with nonmyeloablative conditioning.
Transplantation 20120315
-
Macrophage-induced tumor angiogenesis is regulated by the TSC2-mTOR pathway.
Cancer research 20120315
-
Phospho-specific flow: fixating on the target.
Clinical cancer research : an official journal of the American Association for Cancer Research 20120315
-
Effect of everolimus on left ventricular hypertrophy of de novo kidney transplant recipients: a 1 year, randomized, controlled trial.
Transplantation 20120315
-
Ovarian toxicity from sirolimus.
The New England journal of medicine 20120315
-
PIK3CA/PTEN mutations and Akt activation as markers of sensitivity to allosteric mTOR inhibitors.
Clinical cancer research : an official journal of the American Association for Cancer Research 20120315
-
Randomized comparison of everolimus-eluting and sirolimus-eluting stents in patients treated with percutaneous coronary intervention: the Scandinavian Organization for Randomized Trials with Clinical Outcome IV (SORT OUT IV).
Circulation 20120313
-
Phase II study of everolimus with biomarker exploration in patients with advanced gastric cancer refractory to chemotherapy including fluoropyrimidine and platinum.
British journal of cancer 20120313
-
Ridaforolimus in advanced sarcomas: a leap forward or missed opportunity?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120310
-
Spatio-temporal manipulation of small GTPase activity at subcellular level and on timescale of seconds in living cells.
Journal of visualized experiments : JoVE 20120309
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing.
The New England journal of medicine 20120308
-
Very late coronary stent thrombosis of a newer-generation everolimus-eluting stent compared with early-generation drug-eluting stents: a prospective cohort study.
Circulation 20120306
-
Synergistic anti-tumor effects of RAD001 with MEK inhibitors in neuroendocrine tumors: a potential mechanism of therapeutic limitation of mTOR inhibitor.
Molecular and cellular endocrinology 20120305
-
Quantitative multi-modality imaging analysis of a fully bioresorbable stent: a head-to-head comparison between QCA, IVUS and OCT.
The international journal of cardiovascular imaging 20120301
-
Rapamycin attenuates the expression of cocaine-induced place preference and behavioral sensitization.
Addiction biology 20120301
-
Favorable neointimal coverage in everolimus-eluting stent at 9 months after stent implantation: comparison with sirolimus-eluting stent using optical coherence tomography.
The international journal of cardiovascular imaging 20120301
-
Evaluation with in vivo optical coherence tomography and histology of the vascular effects of the everolimus-eluting bioresorbable vascular scaffold at two years following implantation in a healthy porcine coronary artery model: implications of pilot results for future pre-clinical studies.
The international journal of cardiovascular imaging 20120301
-
Perioperative rupture of the LIMA graft leading to cardiogenic shock, emergency angiography, and stenting with a polytetrafluoroethylene-covered stent.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301
-
Decreased risk of stent fracture-related restenosis between paclitaxel-eluting stents and sirolimus eluting stents: results of long-term follow-up.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301
-
Incomplete arterial healing 8 years after the implantation of sirolimus-eluting stent. In vivo visualization by optical coherence tomography.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301
-
Resolute Italian study in all comers: immediate and one-year outcomes.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301
-
Sirolimus-eluting stent fracture detection by three-dimensional optical coherence tomography.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301
-
Effects of everolimus in combination with sildenafil in monocrotaline-induced pulmonary hypertension in rats.
Cardiovascular toxicology 20120301
-
New targeted therapies in pituitary carcinoma resistant to temozolomide.
Pituitary 20120301
-
[Topical rapamycin solution to treat multiple facial angiofibromas in a patient with tuberous sclerosis].
Actas dermo-sifiliograficas 20120301
-
A phase I study of daily everolimus plus low-dose weekly cisplatin for patients with advanced solid tumors.
Cancer chemotherapy and pharmacology 20120301
-
Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition.
Human molecular genetics 20120301
-
Withdrawal of proliferation signal inhibitors due to adverse events in the maintenance phase of heart transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120301
-
Synergistic activity of rapamycin and dexamethasone in vitro and in vivo in acute lymphoblastic leukemia via cell-cycle arrest and apoptosis.
Leukemia research 20120301
-
Erk1/2 MAPK and mTOR signaling sequentially regulates progression through distinct stages of oligodendrocyte differentiation.
Glia 20120301
-
[Renal tolerance of targeted therapies].
Bulletin du cancer 20120301
-
Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma.
Neuro-oncology 20120301
-
Nutritional and hormonal regulation of the TOR effector 4E-binding protein (4E-BP) in the mosquito Aedes aegypti.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120301
-
Phase I trial of everolimus plus sorafenib for patients with advanced renal cell cancer.
Clinical genitourinary cancer 20120301
-
Clinical review: Current scientific rationale for the use of somatostatin analogs and mTOR inhibitors in neuroendocrine tumor therapy.
The Journal of clinical endocrinology and metabolism 20120301
-
Role and therapeutic potential of PI3K-mTOR signaling in de novo resistance to BRAF inhibition.
Pigment cell & melanoma research 20120301
-
Impairment of object recognition memory by rapamycin inhibition of mTOR in the amygdala or hippocampus around the time of learning or reactivation.
Behavioural brain research 20120301
-
Sorafenib, a multikinase inhibitor, is effective in vitro against non-Hodgkin lymphoma and synergizes with the mTOR inhibitor rapamycin.
American journal of hematology 20120301
-
Inhibition of MTOR disrupts autophagic flux in podocytes.
Journal of the American Society of Nephrology : JASN 20120301
-
Circumferential evaluation of the neointima by optical coherence tomography after ABSORB bioresorbable vascular scaffold implantation: can the scaffold cap the plaque?
Atherosclerosis 20120301
-
Rapamycin exerts antifungal activity in vitro and in vivo against Mucor circinelloides via FKBP12-dependent inhibition of Tor.
Eukaryotic cell 20120301
-
Sirolimus conversion regimen versus continued calcineurin inhibitors in liver allograft recipients: a randomized trial.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120301
-
The effects of immunosuppressants on vascular function, systemic oxidative stress and inflammation in rats.
Transplant international : official journal of the European Society for Organ Transplantation 20120301
-
Safety and efficacy of local periadventitial delivery of sirolimus for improving hemodialysis graft patency: first human experience with a sirolimus-eluting collagen membrane (Coll-R).
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120301
-
Better stent expansion by two-time inflation of stent balloon and its responsible mechanism.
Journal of cardiology 20120301
-
Rapamycin prevents the mutant huntingtin-suppressed GLT-1 expression in cultured astrocytes.
Acta pharmacologica Sinica 20120301
-
Polycystic kidney disease: a 2011 update.
Current opinion in nephrology and hypertension 20120301
-
mTOR inhibitors and its role in the treatment of head and neck squamous cell carcinoma.
Current treatment options in oncology 20120301
-
Long-term kidney allograft function and survival in prednisone-free regimens: tacrolimus/mycophenolate mofetil versus tacrolimus/sirolimus.
Clinical journal of the American Society of Nephrology : CJASN 20120301
-
Sirolimus conversion for renal dysfunction in liver transplant recipients: the devil really is in the details….
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120301
-
Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death.
Autophagy 20120301
-
Identification of autophagosome-associated proteins and regulators by quantitative proteomic analysis and genetic screens.
Molecular & cellular proteomics : MCP 20120301
-
Comparing outcomes after off-pump coronary artery bypass versus drug-eluting stent in diabetic patients.
Journal of cardiology 20120301
-
The haemodialysis arteriovenous graft: is a new era coming?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120301
-
Fatal acute pulmonary injury associated with everolimus.
The Annals of pharmacotherapy 20120301
-
Improvement in renal function after everolimus introduction and calcineurin inhibitor reduction in maintenance thoracic transplant recipients: the significance of baseline glomerular filtration rate.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120301
-
Molecular/genetic therapies in ovarian cancer: future opportunities and challenges.
Clinical obstetrics and gynecology 20120301
-
Fixing a broken stent.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301
-
Rapamycin slows aging in mice.
Cell cycle (Georgetown, Tex.) 20120301
-
Leptin regulates proliferation and apoptosis of colorectal carcinoma through PI3K/Akt/mTOR signalling pathway.
Journal of biosciences 20120301
-
Current status of immunosuppressive agents for solid organ transplantation in children.
Pediatric transplantation 20120301
-
Successful resolution of inflammation and increased regulatory T cells in sirolimus-treated post-transplant allograft hepatitis.
Pediatric transplantation 20120301
-
Autophagy regulates endoplasmic reticulum stress in ischemic preconditioning.
Autophagy 20120301
-
Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy.
Cell death & disease 20120301
-
Advances in the treatment of relapsed or refractory Hodgkin's lymphoma.
The oncologist 20120301
-
Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging.
Aging 20120301
-
mTOR kinase inhibitors as a treatment strategy in hematological malignancies.
Future medicinal chemistry 20120301
-
Five-year follow-up of the Sirolimus-Eluting Stents vs Vascular Brachytherapy for Bare Metal In-Stent Restenosis (SISR) trial.
American heart journal 20120301
-
Five-year results of the Multicenter Randomized Controlled Open-Label Study of the CYPHER Sirolimus-Eluting Stent in the Treatment of Diabetic Patients with De Novo Native Coronary Artery Lesions (SCORPIUS) study: a German multicenter investigation on the effectiveness of sirolimus-eluting stents in diabetic patients.
American heart journal 20120301
-
Comparison of drug-eluting and bare-metal stents for primary percutaneous coronary intervention with or without abciximab in ST-segment elevation myocardial infarction: DEBATER: the Eindhoven reperfusion study.
JACC. Cardiovascular interventions 20120301
-
Delamination of abluminal polymer of biolimus-eluting stent.
JACC. Cardiovascular interventions 20120301
-
LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis, and associates with the activated b-Raf-ERK1/2-mTOR pathway in breast cancer patients.
PLoS genetics 20120301
-
SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians.
PLoS genetics 20120301
-
Rapamycin inhibits lymphatic endothelial cell tube formation by downregulating vascular endothelial growth factor receptor 3 protein expression.
Neoplasia (New York, N.Y.) 20120301
-
First report of a novel abluminal groove filled biodegradable polymer rapamycin-eluting stent in de novo coronary artery disease: results of the first in man FIREHAWK trial.
Chinese medical journal 20120301
-
Safety and efficacy of cobalt chromium alloy based sirolimus-eluting stent with bioabsorbable polymer in porcine model.
Chinese medical journal 20120301
-
[Rapamycin treatment of recurrent autoimmune hemolytic anemia in 28 cases].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20120301
-
Everolimus as primary immunosuppression in kidney transplantation: experience in conversion from calcineurin inhibitors.
Transplantation 20120227
-
Rapamycin reduces clinical signs and neuropathic pain in a chronic model of experimental autoimmune encephalomyelitis.
Journal of neuroimmunology 20120227
-
Drug interaction between cyclosporine and mTOR inhibitors in experimental model of chronic cyclosporine nephrotoxicity and pancreatic islet dysfunction.
Transplantation 20120227
-
Aberrant activation of the mTOR pathway and anti-tumour effect of everolimus on oesophageal squamous cell carcinoma.
British journal of cancer 20120227
-
Amplification and demultiplexing in insulin-regulated Akt protein kinase pathway in adipocytes.
The Journal of biological chemistry 20120224
-
Everolimus alters white matter diffusion in tuberous sclerosis complex.
Neurology 20120221
-
New therapies for tuber-less sclerosis: white matter matters?
Neurology 20120221
-
How many therapeutic options are there for recurrent or metastatic salivary duct carcinoma?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120220
-
Inhibition of rapamycin-induced autophagy causes necrotic cell death associated with Bax/Bad mitochondrial translocation.
Neuroscience 20120217
-
Post-treatment with rapamycin does not prevent epileptogenesis in the amygdala stimulation model of temporal lobe epilepsy.
Neuroscience letters 20120216
-
Akt and p53 are potential mediators of reduced mammary tumor growth by cloroquine and the mTOR inhibitor RAD001.
Biochemical pharmacology 20120215
-
Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20120215
-
Randomized phase II trial of sorafenib with temsirolimus or tipifarnib in untreated metastatic melanoma (S0438).
Clinical cancer research : an official journal of the American Association for Cancer Research 20120215
-
Breast Cancer: Blocking both driver and escape pathways improves outcomes.
Nature reviews. Clinical oncology 20120214
-
MNK2 inhibits eIF4G activation through a pathway involving serine-arginine-rich protein kinase in skeletal muscle.
Science signaling 20120214
-
[Proliferation effects of sirolimus, cyclosporine A and mycophenolate mofetil on human transitional cell carcinoma cells].
Zhonghua yi xue za zhi 20120214
-
Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation.
The Journal of biological chemistry 20120210
-
Treatment of patients with advanced neurofibromatosis type 2 with novel molecularly targeted therapies: from bench to bedside.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120210
-
Improved insulin sensitivity by rapamycin is associated with reduction of mTOR and S6K1 activities in L6 myotubes.
Biochemical and biophysical research communications 20120210
-
Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer.
The New England journal of medicine 20120209
-
Sirolimus as primary immunosuppression attenuates allograft vasculopathy with improved late survival and decreased cardiac events after cardiac transplantation.
Circulation 20120207
-
Forced degradation studies of rapamycin: identification of autoxidation products.
Journal of pharmaceutical and biomedical analysis 20120205
-
[Effect of casamino acid on intergeneric conjugation in rapamycin-producing Streptomyces hygroscopicus ATCC29253].
Wei sheng wu xue bao = Acta microbiologica Sinica 20120204
-
Formation of tRNA granules in the nucleus of heat-induced human cells.
Biochemical and biophysical research communications 20120203
-
Successful treatment of angiofibromata of tuberous sclerosis complex with rapamycin.
The Journal of dermatological treatment 20120201
-
The combination of the novel glycolysis inhibitor 3-BrOP and rapamycin is effective against neuroblastoma.
Investigational new drugs 20120201
-
Schedule-dependent inhibition of T-cell lymphoma cells by cotreatment with the mTOR inhibitor everolimus and anticancer drugs.
Investigational new drugs 20120201
-
Preclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging.
Pediatric blood & cancer 20120201
-
Aprepitant (Emend) significantly increases sirolimus levels in patients undergoing allogeneic hematopoietic SCT.
Bone marrow transplantation 20120201
-
Cardiac tamponade potentially related to sirolimus following cord blood transplantation.
Bone marrow transplantation 20120201
-
Sustained clinical safety and efficacy of a biodegradable-polymer coated sirolimus-eluting stent in 'real-world' practice: three-year outcomes of the CREATE (Multi-Center Registry of EXCEL Biodegradable Polymer Drug Eluting Stents) study.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120201
-
mTOR signaling pathway regulates the IL-12/IL-10 axis in Leishmania donovani infection.
Medical microbiology and immunology 20120201
-
Effect of different immunosuppressive regimens on the evolution of distinct metabolic parameters: evidence from the Symphony study.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120201
-
[Sirolimus-eluting stent displaced fracture: case report and review of the literature].
Annales de cardiologie et d'angeiologie 20120201
-
Preparation and influencing factors of sirolimus liposome by supercritical fluid.
Artificial cells, blood substitutes, and immobilization biotechnology 20120201
-
[PI3K-AKT-mTOR pathway and cancer].
Bulletin du cancer 20120201
-
mTOR inhibition and erythropoiesis: microcytosis or anaemia?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120201
-
An international expanded-access programme of everolimus: addressing safety and efficacy in patients with metastatic renal cell carcinoma who progress after initial vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy.
European journal of cancer (Oxford, England : 1990) 20120201
-
[Intermittent fever under iatrogenic immunosuppression].
Der Internist 20120201
-
Mammalian target of rapamycin (mTOR) inhibitors slow skin carcinogenesis, but impair wound healing.
The British journal of dermatology 20120201
-
mTOR as a therapeutic target in patients with gastric cancer.
International journal of cancer 20120201
-
mTOR is a selective effector of the radiation therapy response in androgen receptor-positive prostate cancer.
Endocrine-related cancer 20120201
-
EGFR- and AKT-mediated reduction in PTEN expression contributes to tyrphostin resistance and is reversed by mTOR inhibition in endometrial cancer cells.
Molecular and cellular biochemistry 20120201
-
Antirestenotic mechanisms of everolimus on human coronary artery smooth muscle cells: inhibition of human coronary artery smooth muscle cell proliferation, but not migration.
Journal of cardiovascular pharmacology 20120201
-
Rapamycin provides a therapeutic option through inhibition of mTOR signaling in chronic myelogenous leukemia.
Oncology reports 20120201
-
Activation of mTOR by human T-cell leukemia virus type 1 Tax is important for the transformation of mouse T cells to interleukin-2-independent growth.
Cancer science 20120201
-
Five-year clinical outcome after primary stenting of totally occluded native coronary arteries: a randomised comparison of bare metal stent implantation with sirolimus-eluting stent implantation for the treatment of total coronary occlusions (PRISON II study).
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120201
-
Pharmacokinetic analysis after implantation of everolimus-eluting self-expanding stents in the peripheral vasculature.
Journal of vascular surgery 20120201
-
Insulin-induced mTOR activity exhibits anti-hepatitis C virus activity.
Molecular medicine reports 20120201
-
Clinical outcomes in kidney transplant recipients receiving long-term therapy with inhibitors of the mammalian target of rapamycin.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120201
-
Focal adhesion kinase governs cardiac concentric hypertrophic growth by activating the AKT and mTOR pathways.
Journal of molecular and cellular cardiology 20120201
-
Differential mTOR and ERK pathway utilization by effector CD4 T cells suggests combinatorial drug therapy of arthritis.
Clinical immunology (Orlando, Fla.) 20120201
-
Novel role of c-jun N-terminal kinase in regulating the initiation of cap-dependent translation.
International journal of oncology 20120201
-
Vascular disruption in combination with mTOR inhibition in renal cell carcinoma.
Molecular cancer therapeutics 20120201
-
Gene expression profile in response to doxorubicin-rapamycin combined treatment of HER-2-overexpressing human mammary epithelial cell lines.
Molecular cancer therapeutics 20120201
-
Successful and cost-efficient replacement of immunoassays by tandem mass spectrometry for the quantification of immunosuppressants in the clinical laboratory.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120201
-
Sorafenib and Mek inhibition is synergistic in medullary thyroid carcinoma in vitro.
Endocrine-related cancer 20120201
-
Tuberous sclerosis complex-associated angiomyolipomas: focus on mTOR inhibition.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20120201
-
Everolimus: in patients with subependymal giant cell astrocytoma associated with tuberous sclerosis complex.
Paediatric drugs 20120201
-
Tregs: application for solid-organ transplantation.
Current opinion in organ transplantation 20120201
-
Calorie restriction and rapamycin inhibit MMTV-Wnt-1 mammary tumor growth in a mouse model of postmenopausal obesity.
Endocrine-related cancer 20120201
-
New advances in the diagnosis and treatment of autoimmune lymphoproliferative syndrome.
Current opinion in pediatrics 20120201
-
Targeting protein synthesis in a Myc/mTOR-driven model of anorexia-cachexia syndrome delays its onset and prolongs survival.
Cancer research 20120201
-
Major response to everolimus in melanoma with acquired imatinib resistance.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120201
-
Randomized comparison of everolimus-eluting versus bare-metal stents in patients with critical limb ischemia and infrapopliteal arterial occlusive disease.
Journal of vascular surgery 20120201
-
Mammalian target of rapamycin (mTOR) inhibition reduces cerebral vasospasm following a subarachnoid hemorrhage injury in canines.
Experimental neurology 20120201
-
Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia.
Nature neuroscience 20120201
-
The risk of skin rash and stomatitis with the mammalian target of rapamycin inhibitor temsirolimus: a systematic review of the literature and meta-analysis.
European journal of cancer (Oxford, England : 1990) 20120201
-
Everolimus in metastatic renal cell carcinoma: Subgroup analysis of patients with 1 or 2 previous vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapies enrolled in the phase III RECORD-1 study.
European journal of cancer (Oxford, England : 1990) 20120201
-
L-leucine alters pancreatic β-cell differentiation and function via the mTor signaling pathway.
Diabetes 20120201
-
Rapalogs in viral cancers.
Expert opinion on investigational drugs 20120201
-
The CXCR4 antagonist POL5551 is equally effective as sirolimus in reducing neointima formation without impairing re-endothelialisation.
Thrombosis and haemostasis 20120201
-
Intrabiliary rapamycin may slow progression of primary sclerosing cholangitis.
Alimentary pharmacology & therapeutics 20120201
-
Stimulation of autophagy by rapamycin protects neurons from remote degeneration after acute focal brain damage.
Autophagy 20120201
-
miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1.
Autophagy 20120201
-
[Hepatocellular carcinoma: what's new?].
Deutsche medizinische Wochenschrift (1946) 20120201
-
Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy.
Autophagy 20120201
-
Roles of the mammalian target of rapamycin, mTOR, in controlling ribosome biogenesis and protein synthesis.
Biochemical Society transactions 20120201
-
Target of rapamcyin (TOR)-based therapeutics for cardiomyopathy: insights from zebrafish genetics.
Cell cycle (Georgetown, Tex.) 20120201
-
Increasingly aggressive endovascular management of tibial artery occlusive disease.
Journal of vascular surgery 20120201
-
Creating biodegradable-polymer drug-eluting stents: shortening the duration of polymer and dual antiplatelet therapy while lengthening the follow-up.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120201
-
Deregulated mTOR-mediated translation in intellectual disability.
Progress in neurobiology 20120201
-
Mechanism of edge restenosis after sirolimus-eluting stent implantation.
The Journal of invasive cardiology 20120201
-
Topical 0.1% rapamycin for angiofibromas in paediatric patients with tuberous sclerosis: a pilot study of four patients.
The Australasian journal of dermatology 20120201
-
Long-term outcome of conversion to sirolimus monotherapy after liver transplant.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120201
-
Sirolimus-eluting stents for the treatment of infrapopliteal arteries in chronic limb ischemia: long-term clinical and angiographic follow-up.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20120201
-
Prime time for infrapopliteal drug-eluting stents?
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20120201
-
Advantages of novel BioMimeTM Sirolimus Eluting Coronary Stent system. Moving towards biomimicry.
Minerva cardioangiologica 20120201
-
Comparison of early and late conversion of sirolimus in experimental model of chronic cyclosporine nephropathy.
Journal of Korean medical science 20120201
-
Surgical treatment of entrapped intravascular ultrasonography catheter.
General thoracic and cardiovascular surgery 20120201
-
Side branch fractional flow reserve measurements after main vessel stenting: a Nordic-Baltic Bifurcation Study III substudy.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120201
-
One-year outcomes of patients with the zotarolimus-eluting coronary stent: RESOLUTE International Registry.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120201
-
Calcified in-stent restenosis: a rare cause of dilation failure requiring rotational atherectomy.
Circulation. Cardiovascular interventions 20120201
-
OCT-verified neointimal hyperplasia is increased at fracture site in drug-eluting stents.
JACC. Cardiovascular imaging 20120201
-
Automated image analysis of nuclear shape: what can we learn from a prematurely aged cell?
Aging 20120201
-
Molecular imaging of drug-eluting coronary stents: method development, optimization and selected applications.
Journal of mass spectrometry : JMS 20120201
-
Long-term comparison of everolimus- and sirolimus-eluting stents in patients with acute coronary syndromes.
JACC. Cardiovascular interventions 20120201
-
No evidence of 'obesity paradox' after treatment with drug-eluting stents in a routine clinical practice: results from the prospective multicenter German DES.DE (German Drug-Eluting Stent) Registry.
JACC. Cardiovascular interventions 20120201
-
[Immunogenetic diagnosis of large granular lymphocytic leukemia and therapy by sirolimus].
Zhongguo shi yan xue ye xue za zhi 20120201
-
[Effect of granulocyte-macrophage colony-stimulating factor on the mammalian target of sirolimus signaling pathway in the wound of rat].
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20120201
-
[Sirolimus use in heart transplantation recipients with chronic renal dysfunction].
Zhonghua xin xue guan bing za zhi 20120201
-
Target of rapamycin (TOR)-based therapy for cardiomyopathy: evidence from zebrafish and human studies.
Trends in cardiovascular medicine 20120201
-
Very late stent thrombosis and late target lesion revascularization after sirolimus-eluting stent implantation: five-year outcome of the j-Cypher Registry.
Circulation 20120131
-
Very late stent thrombosis and late target lesion revascularization: no end in sight.
Circulation 20120131
-
Rapamycin inhibits osteolysis and improves survival in a model of experimental bone metastases.
Cancer letters 20120128
-
Saccharomyces cerevisiae Tel2 plays roles in TORC signaling and telomere maintenance that can be mutationally separated.
Biochemical and biophysical research communications 20120127
-
Response to 'Sirolimus or paclitaxel drug eluting stent in left main disease: the winner is...'.
International journal of cardiology 20120126
-
Influenza virus polymerase confers independence of the cellular cap-binding factor eIF4E for viral mRNA translation.
Virology 20120120
-
Rapamycin and glucose-target of rapamycin (TOR) protein signaling in plants.
The Journal of biological chemistry 20120120
-
Targeted therapies for renal cell carcinoma: review of adverse event management strategies.
Journal of the National Cancer Institute 20120118
-
Optimization of rapamycin-loaded acetalated dextran microparticles for immunosuppression.
International journal of pharmaceutics 20120117
-
Activation of mTOR/p70S6 kinase by ANG II inhibits insulin-stimulated endothelial nitric oxide synthase and vasodilation.
American journal of physiology. Endocrinology and metabolism 20120115
-
Leucine and arginine regulate trophoblast motility through mTOR-dependent and independent pathways in the preimplantation mouse embryo.
Developmental biology 20120115
-
Impact of early conversion from tacrolimus to sirolimus on chronic allograft changes in kidney recipients on rapid steroid withdrawal.
Transplantation 20120115
-
Rapamycin combined with TGF-β converts human invariant NKT cells into suppressive Foxp3+ regulatory cells.
Journal of immunology (Baltimore, Md. : 1950) 20120115
-
Facial angiofibromas treated with topical rapamycin: an excellent choice with fast response.
Dermatology online journal 20120115
-
Comparison of drug-eluting versus bare-metal stent implantation in ST-elevation myocardial infarction patients with renal insufficiency: results from the national registry in Korea.
International journal of cardiology 20120112
-
Dual mTORC1/mTORC2 inhibition diminishes Akt activation and induces Puma-dependent apoptosis in lymphoid malignancies.
Blood 20120112
-
CB2 cannabinoid receptors promote neural progenitor cell proliferation via mTORC1 signaling.
The Journal of biological chemistry 20120106
-
Hyperpolarized 13C MR spectroscopic imaging can be used to monitor Everolimus treatment in vivo in an orthotopic rodent model of glioblastoma.
NeuroImage 20120102
-
Rictor-dependent AKT activation and inhibition of urothelial carcinoma by rapamycin.
Urologic oncology 20120101
-
mTOR pathway inhibition in renal cell carcinoma.
Urologic oncology 20120101
-
An update on targeted therapy in metastatic renal cell carcinoma.
Urologic oncology 20120101
-
Morphological and functional evaluation of the bioresorption of the bioresorbable everolimus-eluting vascular scaffold using IVUS, echogenicity and vasomotion testing at two year follow-up: a patient level insight into the ABSORB A clinical trial.
The international journal of cardiovascular imaging 20120101
-
Reproducibility of Shin's method for necrotic core and calcium content in atherosclerotic coronary lesions treated with bioresorbable everolimus-eluting vascular scaffolds using volumetric intravascular ultrasound radiofrequency-based analysis.
The international journal of cardiovascular imaging 20120101
-
Pharmacokinetics and pharmacodynamics of mycophenolate sodium (EC-MPS) co-administered with cyclosporine in the early-phase post-kidney transplantation.
Clinical transplantation 20120101
-
Long-term effects on renal function of dose-reduced calcineurin inhibitor and sirolimus in cardiac transplant patients.
Clinical transplantation 20120101
-
The effect of mTOR inhibition alone or combined with MEK inhibitors on brain metastasis: an in vivo analysis in triple-negative breast cancer models.
Breast cancer research and treatment 20120101
-
A case of subacute thrombosis associated with clopidogrel resistance after implantation of a zotarolimus-eluting stent.
Heart and vessels 20120101
-
Temsirolimus in combination with carboplatin and paclitaxel in patients with advanced solid tumors: a NCIC-CTG, phase I, open-label dose-escalation study (IND 179).
Annals of oncology : official journal of the European Society for Medical Oncology 20120101
-
Third in-stent restenosis in sirolimus eluting stents: predictors of the next restenosis.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120101
-
Pathological features of in-stent restenosis after sirolimus-eluting stent versus bare metal stent placement.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 20120101
-
Rapamycin decreases survivin expression to induce NSCLC cell apoptosis under hypoxia through inhibiting HIF-1α induction.
Molecular biology reports 20120101
-
Sirolimus-based regimen is associated with decreased expression of glomerular vascular endothelial growth factor.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120101
-
Usefulness of preclinical models for assessing the efficacy of late-life interventions for sarcopenia.
The journals of gerontology. Series A, Biological sciences and medical sciences 20120101
-
Evaluating rational non-cross-resistant combination therapy in advanced clear cell renal cell carcinoma: combined mTOR and AKT inhibitor therapy.
Cancer chemotherapy and pharmacology 20120101
-
Safety and efficacy of temsirolimus in heavily pretreated patients with metastatic renal cell carcinoma.
Acta oncologica (Stockholm, Sweden) 20120101
-
The use of sirolimus should be restricted in liver transplantation.
Journal of hepatology 20120101
-
Hyperactivation of mTOR critically regulates abnormal osteoclastogenesis in neurofibromatosis Type 1.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20120101
-
Caloric restriction and chronic inflammatory diseases.
Oral diseases 20120101
-
Sirolimus--it doesn't deserve its bad Rap(a).
Journal of hepatology 20120101
-
Rapamycin reduces oxidative stress in frataxin-deficient yeast cells.
Mitochondrion 20120101
-
Is advanced hepatocellular carcinoma amenable of cure by liver transplantation with sorafenib as a neoadjuvant approach plus m-TOR inhibitors monotherapy?
Journal of surgical oncology 20120101
-
Erythropoietin mediated bone formation is regulated by mTOR signaling.
Journal of cellular biochemistry 20120101
-
S6K inhibition renders cardiac protection against myocardial infarction through PDK1 phosphorylation of Akt.
The Biochemical journal 20120101
-
Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin.
Neurobiology of disease 20120101
-
GADD34 mediates cytoprotective autophagy in mutant huntingtin expressing cells via the mTOR pathway.
Experimental cell research 20120101
-
CD40 blockade combines with CTLA4Ig and sirolimus to produce mixed chimerism in an MHC-defined rhesus macaque transplant model.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120101
-
Efficacy and safety of sorafenib in combination with mammalian target of rapamycin inhibitors for recurrent hepatocellular carcinoma after liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120101
-
Everolimus-eluting stents for treatment of chronic total coronary occlusions.
Clinical research in cardiology : official journal of the German Cardiac Society 20120101
-
Clinical long-term outcome after implantation of titanium nitride-oxide coated stents compared with paclitaxel- or sirolimus-eluting stents: propensity-score matched analysis.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101
-
Four-year clinical follow-up of the ABSORB everolimus-eluting bioresorbable vascular scaffold in patients with de novo coronary artery disease: the ABSORB trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101
-
Campylobacter jejuni induces colitis through activation of mammalian target of rapamycin signaling.
Gastroenterology 20120101
-
Lack of amino acids in mouse hepatocytes in culture induces the selection of preneoplastic cells.
Cellular signalling 20120101
-
Sirolimus-based immunosuppression in liver transplantation for hepatocellular carcinoma: a meta-analysis.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120101
-
Rapamycin causes upregulation of autophagy and impairs islets function both in vitro and in vivo.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120101
-
Pharmacokinetic drug interaction between AEE788 and RAD001 causing thrombocytopenia in patients with glioblastoma.
Cancer chemotherapy and pharmacology 20120101
-
Butyrolactone derivative 3-benzyl-5-((2-nitrophenoxy) methyl)-dihydrofuran-2(3H)-one protects against amyloid-β peptides-induced cytotoxicity in PC12 cells.
Journal of Alzheimer's disease : JAD 20120101
-
A theoretical model to characterize the drug release behavior of drug-eluting stents with durable polymer matrix coating.
Journal of biomedical materials research. Part A 20120101
-
Effective everolimus treatment of inoperable, life-threatening subependymal giant cell astrocytoma and intractable epilepsy in a patient with tuberous sclerosis complex.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20120101
-
Impact of calcification on the long-term outcomes of sirolimus-eluting stent implantation: subanalysis of the Cypher Post-Marketing Surveillance Registry.
Circulation journal : official journal of the Japanese Circulation Society 20120101
-
Production of 3-hydroxypropionic acid through propionaldehyde dehydrogenase PduP mediated biosynthetic pathway in Klebsiella pneumoniae.
Bioresource technology 20120101
-
Differential regulation of simultaneous antitumor and alloreactive CD8(+) T-cell responses in the same host by rapamycin.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120101
-
Is there any place for macrolides in mood disorders?
Medical hypotheses 20120101
-
Phase II trial of temsirolimus in children with high-grade glioma, neuroblastoma and rhabdomyosarcoma.
European journal of cancer (Oxford, England : 1990) 20120101
-
Inhibition of mTOR by rapamycin in the amygdala or hippocampus impairs formation and reconsolidation of inhibitory avoidance memory.
Neurobiology of learning and memory 20120101
-
Effect of early conversion from CNI to sirolimus on outcomes in kidney transplant recipients with allograft dysfunction.
Journal of nephrology 20120101
-
Three-year follow-up of sirolimus-eluting stents vs. bare metal stents for acute myocardial infarction.
Circulation journal : official journal of the Japanese Circulation Society 20120101
-
Rapamycin induces Bad phosphorylation in association with its resistance to human lung cancer cells.
Molecular cancer therapeutics 20120101
-
The PTPN11 loss-of-function mutation Q510E-Shp2 causes hypertrophic cardiomyopathy by dysregulating mTOR signaling.
American journal of physiology. Heart and circulatory physiology 20120101
-
Current development of the second generation of mTOR inhibitors as anticancer agents.
Chinese journal of cancer 20120101
-
Rapamycin inhibiting Jurkat T cells viability through changing mRNA expression of serine/threonine protein phosphatase 2A.
Transplant immunology 20120101
-
RhoA and Rho kinase mediate cyclosporine A and sirolimus-induced barrier tightening in renal proximal tubular cells.
The international journal of biochemistry & cell biology 20120101
-
Phase II study of the mammalian target of rapamycin inhibitor ridaforolimus in patients with advanced bone and soft tissue sarcomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120101
-
From node to pathway blockade: lessons learned from targeting mammalian target of rapamycin.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120101
-
Rapamycin inhibits osteoclast formation in giant cell tumor of bone through the C/EBPβ - MafB axis.
Journal of molecular medicine (Berlin, Germany) 20120101
-
Temsirolimus, an mTOR inhibitor, in combination with lower-dose clofarabine as salvage therapy for older patients with acute myeloid leukaemia: results of a phase II GIMEMA study (AML-1107).
British journal of haematology 20120101
-
The type 1 insulin-like growth factor receptor (IGF-IR) pathway is mandatory for the follistatin-induced skeletal muscle hypertrophy.
Endocrinology 20120101
-
Acquired Omenn-like syndrome, a novel posttransplant autoaggression syndrome reversed by rapamycin.
Clinical and vaccine immunology : CVI 20120101
-
Spatial distribution and temporal evolution of scattering centers by optical coherence tomography in the poly(L-lactide) backbone of a bioresorbable vascular scaffold.
Circulation journal : official journal of the Japanese Circulation Society 20120101
-
A randomized, dose-escalation study of subconjunctival and intravitreal injections of sirolimus in patients with diabetic macular edema.
Ophthalmology 20120101
-
Exercise modulates microRNAs that affect the PTEN/mTOR pathway in rats after spinal cord injury.
Experimental neurology 20120101
-
Mammalian target of rapamycin: a signaling kinase for every aspect of cellular life.
Methods in molecular biology (Clifton, N.J.) 20120101
-
Biochemical and pharmacological inhibition of mTOR by rapamycin and an ATP-competitive mTOR inhibitor.
Methods in molecular biology (Clifton, N.J.) 20120101
-
Evaluation of rapamycin-induced cell death.
Methods in molecular biology (Clifton, N.J.) 20120101
-
Evaluation of mTOR-regulated mRNA translation.
Methods in molecular biology (Clifton, N.J.) 20120101
-
A genome-wide RNAi screen for polypeptides that alter rpS6 phosphorylation.
Methods in molecular biology (Clifton, N.J.) 20120101
-
Quantitative visualization of autophagy induction by mTOR inhibitors.
Methods in molecular biology (Clifton, N.J.) 20120101
-
Expanding human T regulatory cells with the mTOR-inhibitor rapamycin.
Methods in molecular biology (Clifton, N.J.) 20120101
-
Rapamycin-induced enhancement of vaccine efficacy in mice.
Methods in molecular biology (Clifton, N.J.) 20120101
-
Exploring functional in vivo consequences of the selective genetic ablation of mTOR signaling in T helper lymphocytes.
Methods in molecular biology (Clifton, N.J.) 20120101
-
Evaluating the therapeutic potential of mTOR inhibitors using mouse genetics.
Methods in molecular biology (Clifton, N.J.) 20120101
-
Inhibition of PI3K-Akt-mTOR signaling in glioblastoma by mTORC1/2 inhibitors.
Methods in molecular biology (Clifton, N.J.) 20120101
-
Assessing the function of mTOR in human embryonic stem cells.
Methods in molecular biology (Clifton, N.J.) 20120101
-
Tissue-specific ablation of Tsc1 in pancreatic beta-cells.
Methods in molecular biology (Clifton, N.J.) 20120101
-
A mouse model of diet-induced obesity and insulin resistance.
Methods in molecular biology (Clifton, N.J.) 20120101
-
Rapamycin as immunosuppressant in murine transplantation model.
Methods in molecular biology (Clifton, N.J.) 20120101
-
Development of ATP-competitive mTOR inhibitors.
Methods in molecular biology (Clifton, N.J.) 20120101
-
Cre8â„¢ coronary stent: preclinical in vivo assessment of a new generation polymer-free DES with Amphilimusâ„¢ formulation.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101
-
Sirolimus-eluting stent vs. everolimus-eluting stent for coronary intervention in patients on chronic hemodialysis.
Circulation journal : official journal of the Japanese Circulation Society 20120101
-
In vivo optical coherence tomography of very late drug-eluting stent thrombosis compared with late in-stent restenosis.
Circulation journal : official journal of the Japanese Circulation Society 20120101
-
Preconditioning donor with a combination of tacrolimus and rapamacyn to decrease ischaemia-reperfusion injury in a rat syngenic kidney transplantation model.
Clinical and experimental immunology 20120101
-
Tacrolimus versus cyclosporine for early steroid withdrawal after renal transplantation.
Journal of nephrology 20120101
-
mTOR inhibitor-associated proteinuria in kidney transplant recipients.
Transplantation reviews (Orlando, Fla.) 20120101
-
Functional characterization of glycine N-methyltransferase and its interactive protein DEPDC6/DEPTOR in hepatocellular carcinoma.
Molecular medicine (Cambridge, Mass.) 20120101
-
An unusual cause of cancer mimicry following liver transplantation.
Annals of hepatology 20120101
-
Rapamycin activates autophagy in Hutchinson-Gilford progeria syndrome: implications for normal aging and age-dependent neurodegenerative disorders.
Autophagy 20120101
-
Sex-specific benefits of sirolimus-eluting stent on long-term outcomes in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: insights from the Multicenter Evaluation of Single High-Dose Bolus Tirofiban Versus Abciximab With Sirolimus-Eluting Stent or Bare-Metal Stent in Acute Myocardial Infarction Study trial.
American heart journal 20120101
-
Drug-eluting stents at a crossroads: the good, the bad and the ugly.
Future cardiology 20120101
-
A double whammy for aging? Rapamycin extends lifespan and inhibits cancer in inbred female mice.
Cell cycle (Georgetown, Tex.) 20120101
-
Repetita iuvant (repeating helps): why another paper on a new stent is important.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101
-
Five-year clinical follow-up from the MISSION! Intervention Study: sirolimus-eluting stent versus bare metal stent implantation in patients with ST-segment elevation myocardial infarction, a randomised controlled trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101
-
Predictors of early and late outcomes after everolimus and paclitaxel-eluting coronary stents.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101
-
Intravascular ultrasound assessment of postprocedural incomplete stent apposition.
The Journal of invasive cardiology 20120101
-
mTOR as a target of everolimus in refractory/relapsed Hodgkin lymphoma.
Current medicinal chemistry 20120101
-
The sirolimus-eluting Cypher Select coronary stent for the treatment of bare-metal and drug-eluting stent restenosis: insights from the e-SELECT (Multicenter Post-Market Surveillance) registry.
JACC. Cardiovascular interventions 20120101
-
Validation of an LC-MS/MS method to determine five immunosuppressants with deuterated internal standards including MPA.
BMC clinical pharmacology 20120101
-
[Drug-induced pneumonitis due to sirolimus: an interaction with atorvastatin?].
Revue des maladies respiratoires 20120101
-
Rapamycin-induced tumor vasculature remodeling in rhabdomyosarcoma xenografts increases the effectiveness of adjuvant ionizing radiation.
Journal of pediatric surgery 20120101
-
A novel application of topical rapamycin formulation, an inhibitor of mTOR, for patients with hypomelanotic macules in tuberous sclerosis complex.
Archives of dermatology 20120101
-
An adaptive group sequential phase II design to compare treatments for survival endpoints in rare patient entities.
Journal of biopharmaceutical statistics 20120101
-
Reversible acute encephalopathy with mutism, induced by calcineurin inhibitors after renal transplantation.
Journal of nephrology 20120101
-
HIV-1 promotes renal tubular epithelial cell protein synthesis: role of mTOR pathway.
PloS one 20120101
-
[Immunosuppression in kidney donors with rapamycin and tacrolimus. Proinflammatory cytokine expression].
Medicina 20120101
-
Additive effectiveness of everolimus plus tamoxifen therapy in treatment of encapsulating peritoneal sclerosis.
Renal failure 20120101
-
Randomized comparison of the efficacy and safety of zotarolimus-eluting stents vs. sirolimus-eluting stents for percutaneous coronary intervention in chronic total occlusion--CAtholic Total Occlusion Study (CATOS) trial.
Circulation journal : official journal of the Japanese Circulation Society 20120101
-
Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells.
Cell death & disease 20120101
-
A new path to longevity.
Scientific American 20120101
-
Everolimus with reduced-dose cyclosporine versus full-dose cyclosporine and mycophenolate in de novo renal transplant patients: a 2-year single-center experience.
Transplantation proceedings 20120101
-
Sirolimus-induced pneumonitis after renal transplantation: a single-center experience.
Transplantation proceedings 20120101
-
Trends in the use of immunosuppressive agents by outpatients after renal transplantation at a medical center in southern Taiwan.
Transplantation proceedings 20120101
-
Trends in maintenance immunosuppressive drugs used in taiwanese kidney transplant recipients: an analysis of the national health insurance research database.
Transplantation proceedings 20120101
-
Statins and stent thrombosis.
Swiss medical weekly 20120101
-
First-in-man study of simvastatin-eluting stent in de novo coronary lesions: the SIMVASTENT study.
Circulation journal : official journal of the Japanese Circulation Society 20120101
-
TSC1/2 signaling complex is essential for peripheral naïve CD8+ T cell survival and homeostasis in mice.
PloS one 20120101
-
Resveratrol inhibits inflammatory responses via the mammalian target of rapamycin signaling pathway in cultured LPS-stimulated microglial cells.
PloS one 20120101
-
Short- and long-term major adverse cardiac events in patients undergoing percutaneous coronary intervention with stenting for acute myocardial infarction complicated by cardiogenic shock.
Cardiology 20120101
-
Bullous pemphigoid in a transplant recipient: is this a sign of allograft rejection?
European journal of dermatology : EJD 20120101
-
Impact of positive peri-stent vascular remodeling after sirolimus-eluting and paclitaxel-eluting stent implantation on 5-year clinical outcomes: intravascular ultrasound analysis from the Poststent Optimal Stent Expansion Trial multicenter randomized trial.
Circulation journal : official journal of the Japanese Circulation Society 20120101
-
Steve Jobs's cancer. Pancreatic neuroendocrine tumors are becoming more common (the bad news) and also more treatable (the good news).
Harvard health letter 20120101
-
Antitumor activities of ATP-competitive inhibitors of mTOR in colon cancer cells.
BMC cancer 20120101
-
Delivering hydrophilic and hydrophobic chemotherapeutics simultaneously by magnetic mesoporous silica nanoparticles to inhibit cancer cells.
International journal of nanomedicine 20120101
-
Effects of STAT3 gene silencing and rapamycin on apoptosis in hepatocarcinoma cells.
International journal of medical sciences 20120101
-
Histological spectrum of pulmonary manifestations in kidney transplant recipients on sirolimus inclusive immunosuppressive regimens.
Diagnostic pathology 20120101
-
Delayed mTOR inhibition with low dose of everolimus reduces TGFβ expression, attenuates proteinuria and renal damage in the renal mass reduction model.
PloS one 20120101
-
Activation of PI3K/AKT and MAPK pathway through a PDGFRβ-dependent feedback loop is involved in rapamycin resistance in hepatocellular carcinoma.
PloS one 20120101
-
Clinical outcomes after treatment of multiple lesions with zotarolimus-eluting versus sirolimus-eluting coronary stents (a SORT OUT III substudy).
BMC cardiovascular disorders 20120101
-
[Metastatic breast cancer. Everolimus --a drug delays the progression of the tumor].
Perspective infirmiere : revue officielle de l'Ordre des infirmieres et infirmiers du Quebec 20120101
-
The 'Harmonizing Optimal Strategy for Treatment of coronary artery stenosis - sAfety & effectiveneSS of drug-elUting stents & antiplatelet REgimen' (HOST-ASSURE) trial: study protocol for a randomized controlled trial.
Trials 20120101
-
A case of Takayasu arteritis with repeated coronary artery restenosis after drug-eluting stent implantation successfully treated with a combination of steroids.
Internal medicine (Tokyo, Japan) 20120101
-
Conversion from everolimus with low-exposure cyclosporine to everolimus with mycophenolate sodium maintenance therapy in kidney transplant recipients: a randomized, open-label multicenter study.
Annals of transplantation 20120101
-
Rapamycin ameliorates kidney fibrosis by inhibiting the activation of mTOR signaling in interstitial macrophages and myofibroblasts.
PloS one 20120101
-
Targeting mTOR pathways in human malignancies.
Current pharmaceutical design 20120101
-
Autophagy-lysosomal pathway is involved in lipid degradation in rat liver.
Physiological research 20120101
-
Growth hormone improves growth retardation induced by rapamycin without blocking its antiproliferative and antiangiogenic effects on rat growth plate.
PloS one 20120101
-
Ex-vivo expanded baboon CD4+ CD25 Hi Treg cells suppress baboon anti-pig T and B cell immune response.
Xenotransplantation 20120101
-
Rapamycin conditioning of dendritic cells differentiated from human ES cells promotes a tolerogenic phenotype.
Journal of biomedicine & biotechnology 20120101
-
Rapamycin sensitive ROS formation and Na(+)/H(+) exchanger activity in dendritic cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
-
Vascular compliance changes of the coronary vessel wall after bioresorbable vascular scaffold implantation in the treated and adjacent segments.
Circulation journal : official journal of the Japanese Circulation Society 20120101
-
Outcomes of patients treated with the everolimus-eluting stent versus the zotarolimus eluting stent in a consecutive cohort of patients at a tertiary medical center.
Vascular health and risk management 20120101
-
Inflammation-driven reprogramming of CD4+ Foxp3+ regulatory T cells into pathogenic Th1/Th17 T effectors is abrogated by mTOR inhibition in vivo.
PloS one 20120101
-
Novel synergistic antitumor effects of rapamycin with bortezomib on hepatocellular carcinoma cells and orthotopic tumor model.
BMC cancer 20120101
-
[Neuroendocrine tumors: the age of targeted therapies].
Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20120101
-
Low dose rapamycin exacerbates autoimmune experimental uveitis.
PloS one 20120101
-
Onychopathy induced by temsirolimus, a mammalian target of rapamycin inhibitor.
Dermatology (Basel, Switzerland) 20120101
-
Preclinical evaluation of injectable sirolimus formulated with polymeric nanoparticle for cancer therapy.
International journal of nanomedicine 20120101
-
Simultaneous determination of cyclosporine A, tacrolimus, sirolimus, and everolimus in whole-blood samples by LC-MS/MS.
TheScientificWorldJournal 20120101
-
Drosophila poly suggests a novel role for the Elongator complex in insulin receptor-target of rapamycin signalling.
Open biology 20120101
-
Genotype-dependent efficacy of a dual PI3K/mTOR inhibitor, NVP-BEZ235, and an mTOR inhibitor, RAD001, in endometrial carcinomas.
PloS one 20120101
-
Sirolimus eluting coronary stent implantation in patients on maintenance hemodialysis: the OUCH study (outcome of cypher stent inhemodialysis patients).
Circulation journal : official journal of the Japanese Circulation Society 20120101
-
Paradoxical effects of rapamycin on experimental house dust mite-induced asthma.
PloS one 20120101
-
Preparation and in vivo evaluation of liposomal everolimus for lung carcinoma and thyroid carcinoma.
Biological & pharmaceutical bulletin 20120101
-
Extensive gene-specific translational reprogramming in a model of B cell differentiation and Abl-dependent transformation.
PloS one 20120101
-
BOLERO-2 - will this change practice in advanced breast cancer?
Breast cancer research : BCR 20120101
-
Comparative vascular responses three months after paclitaxel and everolimus-eluting stent implantation in streptozotocin-induced diabetic porcine coronary arteries.
Cardiovascular diabetology 20120101
-
Coronary artery aneurysm after implantation of an endothelial progenitor cell capturing stent.
Kardiologia polska 20120101
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Tumor growth effects of rapamycin on human biliary tract cancer cells.
European journal of medical research 20120101
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Inhibition of chondrosarcoma growth by mTOR inhibitor in an in vivo syngeneic rat model.
PloS one 20120101
-
Simultaneous determination of cyclosporine, sirolimus, and tacrolimus in whole blood using liquid chromatography-tandem mass spectrometry.
Methods in molecular biology (Clifton, N.J.) 20120101
-
Autophagy influences maternal mRNA degradation and apoptosis in porcine parthenotes developing in vitro.
The Journal of reproduction and development 20120101
-
Everolimus enhances gemcitabine-induced cytotoxicity in bladder-cancer cell lines.
Journal of toxicology and environmental health. Part A 20120101
-
Comparison of long-term clinical outcomes between sirolimus-eluting stents and paclitaxel-eluting stents following rotational atherectomy.
International heart journal 20120101
-
Occurrence of late acquired peri-stent contrast staining: comparison between sirolimus-eluting stents and everolimus-eluting stents.
International heart journal 20120101
-
Successful conversion to everolimus after cytomegalovirus infection in a heart transplant recipient.
International heart journal 20120101
-
A case of pancreatic cancer after heart transplantation.
International heart journal 20120101
-
Current status and perspectives of targeted therapy in well-differentiated neuroendocrine tumors.
Oncology 20120101
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Sunitinib and everolimus in pancreatic neuroendocrine tumors.
Tumori 20120101
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Protective role of p70S6K in intestinal ischemia/reperfusion injury in mice.
PloS one 20120101
-
Sirolimus induced phosphaturia is not caused by inhibition of renal apical sodium phosphate cotransporters.
PloS one 20120101
-
Mid-term clinical outcomes of ACS and non-ACS patients treated with everolimus-eluting stents.
International heart journal 20120101
-
Nuclear-cytoplasmic trafficking of NTF2, the nuclear import receptor for the RanGTPase, is subjected to regulation.
PloS one 20120101
-
BRAFV600E negatively regulates the AKT pathway in melanoma cell lines.
PloS one 20120101
-
Outcomes with various drug eluting or bare metal stents in patients with diabetes mellitus: mixed treatment comparison analysis of 22,844 patient years of follow-up from randomised trials.
BMJ (Clinical research ed.) 20120101
-
Rapamycin inhibits proliferation of hemangioma endothelial cells by reducing HIF-1-dependent expression of VEGF.
PloS one 20120101
-
Impact of rapamycin on peritoneal fibrosis and transport function.
Blood purification 20120101
-
Rapamycin regulates the expression and activity of Krüppel-like transcription factor 2 in human umbilical vein endothelial cells.
PloS one 20120101
-
Tolerance induction by exosomes from immature dendritic cells and rapamycin in a mouse cardiac allograft model.
PloS one 20120101
-
Impact of small molecules immunosuppressants on P-glycoprotein activity and T-cell function.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20120101
-
Progress in strategies for dosage regimen individualization.
Current topics in medicinal chemistry 20120101
-
Amino acids and TOR signaling promote prothoracic gland growth and the initiation of larval molts in the tobacco hornworm Manduca sexta.
PloS one 20120101
-
The mTOR inhibitor rapamycin has limited acute anticonvulsant effects in mice.
PloS one 20120101
-
[Comparing moderately late results of the application of stents coated with a medicinal antiproliferative agent for the treatment of patients with various forms of coronary heart disease: their efficacy and safety].
Klinicheskaia meditsina 20120101
-
The antitumor effect of GDC-0941 alone and in combination with rapamycin in breast cancer cells.
Chemotherapy 20120101
-
Impact of CYP3A4*1B and CYP3A5*3 polymorphisms on the pharmacokinetics of cyclosporine and sirolimus in renal transplant recipients.
Annals of transplantation 20120101
-
Inhibition of autophagy contributes to ischemic postconditioning-induced neuroprotection against focal cerebral ischemia in rats.
PloS one 20120101
-
Flt3L combined with rapamycin promotes cardiac allograft tolerance by inducing regulatory dendritic cells and allograft autophagy in mice.
PloS one 20120101
-
Angiogenesis impairment in diabetes: role of methylglyoxal-induced receptor for advanced glycation endproducts, autophagy and vascular endothelial growth factor receptor 2.
PloS one 20120101
-
Grape polyphenols inhibit Akt/mammalian target of rapamycin signaling and potentiate the effects of gefitinib in breast cancer.
Nutrition and cancer 20120101
-
Low-dose oral sirolimus and the risk of menstrual-cycle disturbances and ovarian cysts: analysis of the randomized controlled SUISSE ADPKD trial.
PloS one 20120101
-
Correcting overall survival for the impact of crossover via a rank-preserving structural failure time (RPSFT) model in the RECORD-1 trial of everolimus in metastatic renal-cell carcinoma.
Journal of biopharmaceutical statistics 20120101
-
Simultaneous very late stent thrombosis in multiple coronary arteries.
Texas Heart Institute journal 20120101
-
Everolimus and sirolimus in combination with cyclosporine have different effects on renal metabolism in the rat.
PloS one 20120101
-
Involvement of phosphatidylinositol 3-kinase/Akt pathway in gemcitabine-induced apoptosis-like cell death in insulinoma cell line INS-1.
Biological & pharmaceutical bulletin 20120101
-
Nitrogen-responsive regulation of GATA protein family activators Gln3 and Gat1 occurs by two distinct pathways, one inhibited by rapamycin and the other by methionine sulfoximine.
The Journal of biological chemistry 20111230
-
Nutrient limitations alter cell division control and chromosome segregation through growth-related kinases and phosphatases.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20111227
-
Associations of ABCB1 3435C>T and IL-10-1082G>A polymorphisms with long-term sirolimus dose requirements in renal transplant patients.
Transplantation 20111227
-
[Conversion from calcineurin inhibitors to sirolimus in chronic allograft nephropathy: a 4-year prospective study].
Zhonghua yi xue za zhi 20111227
-
The cdk1-cyclin B complex is involved in everolimus triggered resistance in the PC3 prostate cancer cell line.
Cancer letters 20111226
-
Defining the role of TORC1/2 in multiple myeloma.
Blood 20111222
-
mTORC1 and mTORC2 differentially regulate homeostasis of neoplastic and non-neoplastic human mast cells.
Blood 20111222
-
Tor complex 1 controls telomere length by affecting the level of Ku.
Current biology : CB 20111220
-
Effect of recombinant human SDF-1a on re-endothelialization after sirolimus-eluting stent implantation in rabbit aorta abdominalis.
Life sciences 20111219
-
Local persistent hypercoagulability after sirolimus-eluting stent implantation in patients with stable angina.
International journal of cardiology 20111215
-
Rapamycin does not control hemophagocytic lymphohistiocytosis in LCMV-infected perforin-deficient mice.
Pediatric blood & cancer 20111215
-
Rapamycin for life: a step to immortality.
Cell cycle (Georgetown, Tex.) 20111215
-
Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice.
Cell cycle (Georgetown, Tex.) 20111215
-
Late-onset proteinuria after antithymocyte globulin induction and de novo sirolimus monotherapy in kidney transplant recipients.
Transplantation 20111215
-
Targeting the mTOR/4E-BP pathway in endometrial cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 20111215
-
Rapamycin-induced glucose intolerance: hunger or starvation diabetes.
Cell cycle (Georgetown, Tex.) 20111215
-
Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival.
Journal of controlled release : official journal of the Controlled Release Society 20111210
-
mTOR inhibitor therapy for patients with carcinoid.
Lancet (London, England) 20111210
-
Everolimus plus octreotide long-acting repeatable for the treatment of advanced neuroendocrine tumours associated with carcinoid syndrome (RADIANT-2): a randomised, placebo-controlled, phase 3 study.
Lancet (London, England) 20111210
-
Fatty acids suppress autophagic turnover in β-cells.
The Journal of biological chemistry 20111209
-
A critical role for GluN2B-containing NMDA receptors in cortical development and function.
Neuron 20111208
-
Polymer drug-eluting stents: is the future biodegradable?
Lancet (London, England) 20111203
-
Long-term clinical outcomes of biodegradable polymer biolimus-eluting stents versus durable polymer sirolimus-eluting stents in patients with coronary artery disease (LEADERS): 4 year follow-up of a randomised non-inferiority trial.
Lancet (London, England) 20111203
-
Phosphorylation of eukaryotic translation initiation factor 4B (EIF4B) by open reading frame 45/p90 ribosomal S6 kinase (ORF45/RSK) signaling axis facilitates protein translation during Kaposi sarcoma-associated herpesvirus (KSHV) lytic replication.
The Journal of biological chemistry 20111202
-
Efficacy of RAD001 (everolimus) against advanced gastric cancer with peritoneal dissemination.
Investigational new drugs 20111201
-
Long-term stable disease in metastatic renal cell carcinoma: sorafenib sequenced to sunitinib and everolimus: a case study.
Medical oncology (Northwood, London, England) 20111201
-
Reactivation of tuberculosis during temsirolimus therapy.
Investigational new drugs 20111201
-
Long-term response with everolimus for metastatic renal cell carcinoma refractory to sunitinib.
Medical oncology (Northwood, London, England) 20111201
-
Role of the mTOR pathway in LPS-activated monocytes: influence of hypertonic saline.
The Journal of surgical research 20111201
-
[Immunosuppressive treatments: mechanisms of action and clinical use].
Nephrologie & therapeutique 20111201
-
Serial coronary angioscopic findings of drug-eluting stents implanted in a chronic totally occluded lesion.
International journal of cardiology 20111201
-
Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity.
International journal of cancer 20111201
-
3-Dimensional reconstruction of a bifurcation lesion with double wire after implantation of a second generation everolimus-eluting bioresorbable vascular scaffold.
International journal of cardiology 20111201
-
Effect of complementary pathway blockade on efficacy of combination enzastaurin and rapamycin.
Head & neck 20111201
-
Sirolimus for the treatment of complicated vascular anomalies in children.
Pediatric blood & cancer 20111201
-
Stimulation of cardiomyogenesis of embryonic stem cells by nitric oxide downstream of AMP-activated protein kinase and mTOR signaling pathways.
Stem cells and development 20111201
-
Sirolimus-eluting stent fracture and aneurysm formation in a young child with a coronary artery bypass graft.
Pediatric cardiology 20111201
-
Very late stent thrombosis due to DES fracture: description of a case and review of potential causes.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20111201
-
Comparison of pharmacokinetics of the limus-eluting stents in Japanese patients.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20111201
-
Sirolimus for refractory vascular anomalies.
Pediatric blood & cancer 20111201
-
Impact of sirolimus, tacrolimus and mycophenolate mofetil on osteoclastogenesis--implications for post-transplantation bone disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111201
-
Immunological aspects of allogeneic and autologous mesenchymal stem cell therapies.
Human gene therapy 20111201
-
Evaluation of the MassTrak Immunosuppressant XE Kit for the determination of everolimus and cyclosporin A in human whole blood employing isotopically labeled internal standards.
Clinical chemistry and laboratory medicine 20111201
-
Steroid or tacrolimus withdrawal in renal transplant recipients using sirolimus.
International urology and nephrology 20111201
-
Inhibitors of mTOR overcome drug resistance from topoisomerase II inhibitors in solid tumors.
Cancer letters 20111201
-
m-TOR inhibitors: what role in liver transplantation?
Journal of hepatology 20111201
-
Comparison of zotarolimus- versus everolimus-eluting stents in the treatment of coronary bifurcation lesions.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20111201
-
Sequence therapy in patients with metastatic renal cell carcinoma: comparison of common targeted treatment options following failure of receptor tyrosine kinase inhibitors.
European urology 20111201
-
Inhibition of induced autophagy increases apoptosis of Nara-H cells.
International journal of oncology 20111201
-
The activation state of the inositol 1,4,5-trisphosphate receptor regulates the velocity of intracellular Ca2+ waves in bovine aortic endothelial cells.
Journal of cellular biochemistry 20111201
-
Combining mTor inhibitors with rapamycin-resistant T cells: a two-pronged approach to tumor elimination.
Molecular therapy : the journal of the American Society of Gene Therapy 20111201
-
TGF-β1 mediates sirolimus and cyclosporine A-induced alteration of barrier function in renal epithelial cells via a noncanonical ERK1/2 signaling pathway.
American journal of physiology. Renal physiology 20111201
-
Three-year clinical outcome with the Endeavorâ„¢ zotarolimus-eluting stent in primary percutaneous coronary intervention for ST elevation myocardial infarction: the Endeavorâ„¢ primary PCI study (E-PPCI).
Journal of interventional cardiology 20111201
-
Renal function in children with heart transplantation after switching to CNI-free immunosuppression with everolimus.
Pediatric transplantation 20111201
-
mTOR: A pathogenic signaling pathway in developmental brain malformations.
Trends in molecular medicine 20111201
-
Therapeutic value of prenatal rapamycin treatment in a mouse brain model of tuberous sclerosis complex.
Human molecular genetics 20111201
-
Multi-Link Vision stent vs. first-generation drug-eluting stents: systematic review and meta-analysis.
QJM : monthly journal of the Association of Physicians 20111201
-
Everolimus in combination with pemetrexed in patients with advanced non-small cell lung cancer previously treated with chemotherapy: a phase I study using a novel, adaptive Bayesian dose-escalation model.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20111201
-
Involvement of the mammalian target of rapamycin signaling in the antidepressant-like effect of group II metabotropic glutamate receptor antagonists.
Neuropharmacology 20111201
-
Rapamycin protects against middle cerebral artery occlusion induced focal cerebral ischemia in rats.
Behavioural brain research 20111201
-
Preclinical testing of PI3K/AKT/mTOR signaling inhibitors in a mouse model of ovarian endometrioid adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20111201
-
Rapamycin decreases airway remodeling and hyperreactivity in a transgenic model of noninflammatory lung disease.
Journal of applied physiology (Bethesda, Md. : 1985) 20111201
-
CNI induced Th17/Treg imbalance and susceptibility to renal dysfunction in renal transplantation.
International immunopharmacology 20111201
-
Performance of everolimus-eluting versus paclitaxel-eluting coronary stents in small vessels: results from the SPIRIT III and SPIRIT IV clinical trials.
Journal of interventional cardiology 20111201
-
Expression of yeast high mobility group protein HMO1 is regulated by TOR signaling.
Gene 20111201
-
[Lymphangioleiomyomatosis: new therapeutic approaches].
Archivos de bronconeumologia 20111201
-
Rapamycin suppresses self-renewal and vasculogenic potential of stem cells isolated from infantile hemangioma.
The Journal of investigative dermatology 20111201
-
Pregnancy under everolimus-based immunosuppression.
Transplant international : official journal of the European Society for Organ Transplantation 20111201
-
SYNTAX score and Clinical SYNTAX score as predictors of very long-term clinical outcomes in patients undergoing percutaneous coronary interventions: a substudy of SIRolimus-eluting stent compared with pacliTAXel-eluting stent for coronary revascularization (SIRTAX) trial.
European heart journal 20111201
-
Do wound complications or lymphoceles occur more often in solid organ transplant recipients on mTOR inhibitors? A systematic review of randomized controlled trials.
Transplant international : official journal of the European Society for Organ Transplantation 20111201
-
Late withdrawal of calcineurin inhibitors and switch to mTOR inhibitors--beneficial or too late?
Pediatric transplantation 20111201
-
Integration of diffusion-weighted MRI data and a simple mathematical model to predict breast tumor cellularity during neoadjuvant chemotherapy.
Magnetic resonance in medicine 20111201
-
Comparison of zotarolimus-eluting stents versus sirolimus-eluting stents versus paclitaxel-eluting stents for primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction: results from the Korean Multicentre Endeavor (KOMER) acute myocardial infarction (AMI) trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111201
-
Focused ultrasound-mediated drug delivery from microbubbles reduces drug dose necessary for therapeutic effect on neointima formation--brief report.
Arteriosclerosis, thrombosis, and vascular biology 20111201
-
Enhanced delivery of rapamycin by V156K-apoA-I high-density lipoprotein inhibits cellular proatherogenic effects and senescence and promotes tissue regeneration.
The journals of gerontology. Series A, Biological sciences and medical sciences 20111201
-
Air-liquid biofilm formation is dependent on ammonium depletion in a Saccharomyces cerevisiae flor strain.
Yeast (Chichester, England) 20111201
-
Neuronal Nogo-A regulates glutamate receptor subunit expression in hippocampal neurons.
Journal of neurochemistry 20111201
-
Chromogranin A and neuron-specific enolase as prognostic markers in patients with advanced pNET treated with everolimus.
The Journal of clinical endocrinology and metabolism 20111201
-
Rapamycin reduces reactive oxygen species in cultured human corneal endothelial cells.
Current eye research 20111201
-
Targeted therapy in sarcomas: mammalian target of rapamycin inhibitors from bench to bedside.
Expert opinion on investigational drugs 20111201
-
Rapamycin attenuates airway hyperreactivity, goblet cells, and IgE in experimental allergic asthma.
Journal of immunology (Baltimore, Md. : 1950) 20111201
-
The metabolic and toxicological considerations for mTOR inhibitors in the treatment of hepatocarcinoma.
Expert opinion on drug metabolism & toxicology 20111201
-
Comprehensive intravascular ultrasound assessment of stent area and its impact on restenosis and adverse cardiac events in 403 patients with unprotected left main disease.
Circulation. Cardiovascular interventions 20111201
-
Infantile hemangioma research: looking backward and forward.
The Journal of investigative dermatology 20111201
-
Expression pattern and functions of autophagy-related gene atg5 in zebrafish organogenesis.
Autophagy 20111201
-
Kinetic nomograms assist individualization of drug regimens.
Clinical pharmacokinetics 20111201
-
Sirolimus in solid organ transplantation: current therapies and new frontiers.
Immunotherapy 20111201
-
Is there a critical period for mossy fiber sprouting in a mouse model of temporal lobe epilepsy?
Epilepsia 20111201
-
Autophagy in atherosclerosis: a potential drug target for plaque stabilization.
Arteriosclerosis, thrombosis, and vascular biology 20111201
-
TFEB, a novel mTORC1 effector implicated in lysosome biogenesis, endocytosis and autophagy.
Cell cycle (Georgetown, Tex.) 20111201
-
CDNA cloning and characterization of S6 kinase and its effect on yolk protein gene expression in the oriental fruit fly Bactrocera dorsalis (Hendel).
Archives of insect biochemistry and physiology 20111201
-
Bifurcation stenting with a provisional T strategy: drug eluting stent type does matter.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20111201
-
Rationale and design of the EXAMINATION trial: a randomised comparison between everolimus-eluting stents and cobalt-chromium bare-metal stents in ST-elevation myocardial infarction.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111201
-
Observations on enhanced port wine stain blanching induced by combined pulsed dye laser and rapamycin administration.
Lasers in surgery and medicine 20111201
-
Anti-inflammatory and anti-fibrotic effects of sirolimus on bleomycin-induced pulmonary fibrosis in rats.
Clinical and investigative medicine. Medecine clinique et experimentale 20111201
-
[Conversion from a calcineurin inhibitor to a sirolimus-based therapy after renal transplantation - An update of existing recommendations].
Deutsche medizinische Wochenschrift (1946) 20111201
-
Deoxyribose protects against rapamycin-induced cytotoxicity in colorectal cancer cells in vitro.
Nucleosides, nucleotides & nucleic acids 20111201
-
[Antihormonal therapy in breast cancer and mTOR inhibitors].
Bulletin du cancer 20111201
-
Activation of mTOR signaling in medullary and aggressive papillary thyroid carcinomas.
Surgery 20111201
-
Risk of target lesion failure in relationship to vessel angiographic geometry and stent conformability using the second generation of drug-eluting stents.
American heart journal 20111201
-
Outcomes in patients undergoing multivessel percutaneous coronary intervention using sirolimus-eluting stents: a report from the e-SELECT registry.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111201
-
Coronary pseudoaneurysm in a non-polymer drug-eluting stent: a rare entity.
Asian cardiovascular & thoracic annals 20111201
-
Allosteric activation of kinases: design and application of RapR kinases.
Current protocols in cell biology 20111201
-
Better actual 10-year renal transplant outcomes of 80% reduced cyclosporine exposure with sirolimus base therapy compared with full cyclosporine exposure without or with concomittant sirolimus treatment.
Transplantation proceedings 20111201
-
Impact of the conversion of the immunosuppressive regimen from prograf to advagraf or to sirolimus in long-term stable liver transplant recipients: indications, safety, and outcome.
Transplantation proceedings 20111201
-
Lipid profile changes during the first year after kidney transplantation: risk factors and influence of the immunosuppressive drug regimen.
Transplantation proceedings 20111201
-
Oxidative stress indices in rats under immunosuppression.
Transplantation proceedings 20111201
-
Stent area by intravascular ultrasound and outcomes in left main intervention with drug-eluting stents: small stents, more events.
Circulation. Cardiovascular interventions 20111201
-
Head-to-head comparison of the neointimal response between metallic and bioresorbable everolimus-eluting scaffolds using optical coherence tomography.
JACC. Cardiovascular interventions 20111201
-
Serial in vivo intravascular ultrasound-based echogenicity changes of everolimus-eluting bioresorbable vascular scaffold during the first 12 months after implantation insights from the ABSORB B trial.
JACC. Cardiovascular interventions 20111201
-
A new era of prospective real-world safety evaluation primary report of XIENCE V USA (XIENCE V Everolimus Eluting Coronary Stent System condition-of-approval post-market study).
JACC. Cardiovascular interventions 20111201
-
Mechanism of activation of AMPK and upregulation of OGG1 by rapamycin in cancer cells.
Oncotarget 20111201
-
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
PLoS computational biology 20111201
-
[What's new in dermatological therapy?].
Annales de dermatologie et de venereologie 20111201
-
Repetitive stent fractures with diffuse coronary artery microaneurysm formation--sirolimus eluting stent hypersensitivity?
Acta clinica Croatica 20111201
-
Sirolimus and tacrolimus as immune prophylaxis compared to cyclosporine with or without methotrexate in patients undergoing allogeneic haematopoietic stem cell transplantation for non-malignant disorders.
European journal of haematology 20111201
-
Combining an EGFR directed tyrosine kinase inhibitor with autophagy-inducing drugs: a beneficial strategy to combat non-small cell lung cancer.
Cancer letters 20111128
-
Everolimus prevents endomyocardial remodeling after heart transplantation.
Transplantation 20111127
-
Treatment of everolimus-resistant metastatic renal cell carcinoma with VEGF-targeted therapies.
British journal of cancer 20111122
-
Small-molecule control of protein degradation using split adaptors.
ACS chemical biology 20111118
-
Chemical tools for studying directed cell migration.
ACS chemical biology 20111118
-
microRNA-101 is a potent inhibitor of autophagy.
The EMBO journal 20111116
-
Phase 1/2 study of everolimus in advanced hepatocellular carcinoma.
Cancer 20111115
-
Stent-related cardiac events beyond three years after implantation of the sirolimus-eluting stent (from the EVASTENT Patients).
The American journal of cardiology 20111115
-
The role of skeletal muscle mTOR in the regulation of mechanical load-induced growth.
The Journal of physiology 20111115
-
Nonobese diabetic natural killer cells: a barrier to allogeneic chimerism that can be reduced by rapamycin.
Transplantation 20111115
-
Decreased lymphangiogenesis and lymph node metastasis by mTOR inhibition in head and neck cancer.
Cancer research 20111115
-
Discovery and SAR exploration of a novel series of imidazo[4,5-b]pyrazin-2-ones as potent and selective mTOR kinase inhibitors.
Bioorganic & medicinal chemistry letters 20111115
-
High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1.
Cell cycle (Georgetown, Tex.) 20111115
-
Five-year outcomes of sirolimus-eluting versus paclitaxel-eluting stents: a propensity matched study: clinical evidence of late catch-up?
International journal of cardiology 20111103
-
Turn motif phosphorylation negatively regulates activation loop phosphorylation in Akt.
Oncogene 20111103
-
Nucleocytoplasmic localization of p70 S6K1, but not of its isoforms p85 and p31, is regulated by TSC2/mTOR.
Oncogene 20111103
-
'Sirolimus or paclitaxel drug eluting stent in left main disease: the winner is... '.
International journal of cardiology 20111103
-
FRET detection of calmodulin binding to the cardiac RyR2 calcium release channel.
Biophysical journal 20111102
-
Acute myocardial infarction related to very late sirolimus-eluting stent thrombosis 6 months after discontinuation of dual antiplatelet therapy.
Journal of cardiovascular medicine (Hagerstown, Md.) 20111101
-
Effect of intravascular ultrasound-guided adjuvant high-pressure non-compliant balloon post-dilation after drug-eluting stent implantation.
Heart and vessels 20111101
-
Utility of myocardial fractional flow reserve for prediction of restenosis following sirolimus-eluting stent implantation.
Heart and vessels 20111101
-
Efficacy of paclitaxel-eluting stent implantation in hemodialysis patients.
Heart and vessels 20111101
-
TGFβ- and bleomycin-induced extracellular matrix synthesis is mediated through Akt and mammalian target of rapamycin (mTOR).
Journal of cellular physiology 20111101
-
[Association of post-transplant lymphoproliferative disease and visceral leishmaniasis after kidney transplantation].
Nephrologie & therapeutique 20111101
-
Low-dose sirolimus combined with angiotensin-converting enzyme inhibitor and statin stabilizes renal function and reduces glomerular proliferation in poor prognosis IgA nephropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111101
-
Influence of MRP2 on MPA pharmacokinetics in renal transplant recipients-results of the Pharmacogenomic Substudy within the Symphony Study.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111101
-
Subconjunctival sirolimus in the treatment of diabetic macular edema.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20111101
-
Autophagy induced by rapamycin and carbon-starvation have distinct proteome profiles in Aspergillus nidulans.
Biotechnology and bioengineering 20111101
-
Chronic hypoxia-induced alterations of key enzymes of glucose oxidative metabolism in developing mouse liver are mTOR dependent.
Molecular and cellular biochemistry 20111101
-
Differences in drug-eluting stents used in coronary artery disease.
The American journal of the medical sciences 20111101
-
Activation of the phosphatidylinositol 3'-kinase/AKT pathway in neuroblastoma and its regulation by thioredoxin 1.
Human pathology 20111101
-
mTOR signaling in polycystic kidney disease.
Trends in molecular medicine 20111101
-
Identification of cancer stem cells in human gastrointestinal carcinoid and neuroendocrine tumors.
Gastroenterology 20111101
-
Cytomegalovirus incidence between everolimus versus mycophenolate in de novo renal transplants: pooled analysis of three clinical trials.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20111101
-
Hydrogel containing L-valine residues as a platform for cisplatin chemotherapy.
Colloids and surfaces. B, Biointerfaces 20111101
-
The role of pre-conversion glomerular filtration rate in predicting long-term renal function after conversion to proliferation signal inhibitors in long-term heart transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20111101
-
Global and threshold-free Transcriptional Regulatory Networks reconstruction through integrating ChIP-Chip and expression data.
Current protein & peptide science 20111101
-
Multimodal biomarker investigation on efficacy and mechanism of action for the mammalian target of rapamycin inhibitor, temsirolimus, in a preclinical mammary carcinoma OncoMouse model: a translational medicine study in support for early clinical development.
The Journal of pharmacology and experimental therapeutics 20111101
-
Comparison of angioscopic findings and three-year cardiac events between sirolimus-eluting stent and bare-metal stent in acute myocardial infarction.
The American journal of cardiology 20111101
-
Monitoring of mycophenolic acid and kidney function during combined immunosuppressive therapy.
Clinical chemistry and laboratory medicine 20111101
-
Hot-topic debate on hepatitis C virus: the type of immunosuppression matters.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20111101
-
Outcome of sirolimus-eluting versus zotarolimus-eluting coronary stent implantation in patients with and without diabetes mellitus (a SORT OUT III Substudy).
The American journal of cardiology 20111101
-
Rapamycin protects against dominant negative-HNF1A-induced apoptosis in INS-1 cells.
Apoptosis : an international journal on programmed cell death 20111101
-
mTORC1 activation triggers the unfolded protein response in podocytes and leads to nephrotic syndrome.
Laboratory investigation; a journal of technical methods and pathology 20111101
-
Elimination of norovirus in a chronic carrier under immunosuppression after heart transplantation--effect of everolimus.
Transplant international : official journal of the European Society for Organ Transplantation 20111101
-
Rapamycin suppresses axon sprouting by somatostatin interneurons in a mouse model of temporal lobe epilepsy.
Epilepsia 20111101
-
Calcineurin inhibitor minimization using sirolimus leads to improved renal function in pediatric heart transplant recipients.
Pediatric transplantation 20111101
-
Calcineurin inhibitors in kidney transplantation: friend or foe?
Current opinion in nephrology and hypertension 20111101
-
A phase I trial of liposomal doxorubicin, bevacizumab, and temsirolimus in patients with advanced gynecologic and breast malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 20111101
-
Emerging roles for mammalian target of rapamycin inhibitors in the treatment of solid tumors and hematological malignancies.
Current opinion in oncology 20111101
-
Systemic inhibition of the mammalian target of rapamycin (mTOR) pathway reduces neuropathic pain in mice.
Pain 20111101
-
Immunosuppressant regimen based on sirolimus decreases aortic stiffness in renal transplant recipients in comparison to cyclosporine.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20111101
-
Role of everolimus in pancreatic neuroendocrine tumors.
Expert review of anticancer therapy 20111101
-
Sirolimus drug-eluting, hydrogel-impregnated polypropylene mesh reduces intra-abdominal adhesion formation in a mouse model.
Surgery 20111101
-
Identifying inhibitors of epithelial-mesenchymal transition by connectivity map-based systems approach.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20111101
-
Limiting hepatitis C virus progression in liver transplant recipients using sirolimus-based immunosuppression.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20111101
-
Sirolimus is coming of age.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20111101
-
Clinical outcome of B2/C type isolated proximal LAD disease treated with drug-eluting stents.
Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20111101
-
Inhibition of the mammalian target of rapamycin blocks epilepsy progression in NS-Pten conditional knockout mice.
Epilepsia 20111101
-
Autophagy and the evasion of host defense: a new variation on the theme for Burkholderia cepacia?
Autophagy 20111101
-
Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis.
Autophagy 20111101
-
Sirolimus in pediatric renal transplantation.
Pediatric transplantation 20111101
-
Sirolimus as renal and immunological rescue agent in pediatric liver transplant recipients.
Pediatric transplantation 20111101
-
In situ quantitative imaging of cellular lipids using molecular sensors.
Nature chemistry 20111101
-
The three year follow-up of the randomised 'all-comers' trial of a biodegradable polymer biolimus-eluting stent versus permanent polymer sirolimus-eluting stent (LEADERS).
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111101
-
mTOR kinase inhibition results in oocyte loss characterized by empty follicles in human ovarian cortical strips cultured in vitro.
Fertility and sterility 20111101
-
Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.
Nature biotechnology 20111101
-
[Second line AUO (Working Group Urological Oncology) study AB 35/09 on metastasized urothelial carcinoma. Phase II study with RAD001 in combination with paclitaxel for patients with metastasized urothelial carcinoma of the urinary bladder after failure of platinum-based chemotherapy (CRAD001)].
Der Urologe. Ausg. A 20111101
-
Successful treatment of a late presentation exercise-induced spontaneous left anterior descending artery dissection.
The Journal of invasive cardiology 20111101
-
The Spanish experience with hand, forearm, and arm transplantation.
Hand clinics 20111101
-
[Management of metastatic neuroendocrine tumors].
Annales de pathologie 20111101
-
Plant TOR signaling components.
Plant signaling & behavior 20111101
-
Statistical analysis of noncommensurate multiple outcomes.
Circulation. Cardiovascular quality and outcomes 20111101
-
Everolimus-induced loss of wound strength can be prevented by a short postoperative delay in its administration.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20111101
-
Long-term tissue coverage of a biodegradable polylactide polymer-coated biolimus-eluting stent: comparative sequential assessment with optical coherence tomography until complete resorption of the polymer.
American heart journal 20111101
-
Mechanisms of very late stent thrombosis after drug-eluting stent implantation: findings from coronary angioscopy and optical coherence tomography.
JACC. Cardiovascular imaging 20111101
-
Short-term immunossupressive treatment of the donor does not prevent ischemia-reperfusion kidney damage in the rat.
Transplantation proceedings 20111101
-
De novo use of everolimus with elimination or minimization of cyclosporine in renal transplant recipients.
Transplantation proceedings 20111101
-
Cost-effectiveness analysis of the early conversion of tacrolimus to mammalian target of rapamycin inhibitors in patients with renal transplantation.
Transplantation proceedings 20111101
-
Impact of lesion length and vessel size on clinical outcomes after percutaneous coronary intervention with everolimus- versus paclitaxel-eluting stents pooled analysis from the SPIRIT (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) and COMPARE (Second-generation everolimus-eluting and paclitaxel-eluting stents in real-life practice) Randomized Trials.
JACC. Cardiovascular interventions 20111101
-
Second-generation everolimus-eluting stents and the beat goes on?
JACC. Cardiovascular interventions 20111101
-
Yeast-like chronological senescence in mammalian cells: phenomenon, mechanism and pharmacological suppression.
Aging 20111101
-
The reverse, but coordinated, roles of Tor2 (TORC1) and Tor1 (TORC2) kinases for growth, cell cycle and separase-mediated mitosis in Schizosaccharomyces pombe.
Open biology 20111101
-
Rapamycin passes the torch: a new generation of mTOR inhibitors.
Nature reviews. Drug discovery 20111031
-
Unprotected left main stenting with a second-generation drug-eluting stent: one-year outcomes of the LEMAX Pilot study.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111030
-
Rapamycin sensitive mTOR activation mediates nerve growth factor (NGF) induced cell migration and pro-survival effects against hydrogen peroxide in retinal pigment epithelial cells.
Biochemical and biophysical research communications 20111028
-
Everolimus-eluting versus sirolimus-eluting stents in patients undergoing percutaneous coronary intervention: the EXCELLENT (Efficacy of Xience/Promus Versus Cypher to Reduce Late Loss After Stenting) randomized trial.
Journal of the American College of Cardiology 20111025
-
Head-to-head randomized comparisons of limus-eluting coronary stents: pursuing excellence or flying too high?
Journal of the American College of Cardiology 20111025
-
Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria.
European journal of histochemistry : EJH 20111019
-
Results of a prospective randomized trial of sirolimus conversion in kidney transplant recipients on early corticosteroid withdrawal.
Transplantation 20111015
-
Switching from calcineurin inhibitors to Mammalian target of rapamycin inhibitors--finally caught the right wave?
Transplantation 20111015
-
mTOR in podocyte function: is rapamycin good for diabetic nephropathy?
Cell cycle (Georgetown, Tex.) 20111015
-
Impact of the everolimus-eluting stent on stent thrombosis: a meta-analysis of 13 randomized trials.
Journal of the American College of Cardiology 20111004
-
Evaluation of the second generation of a bioresorbable everolimus-eluting vascular scaffold for the treatment of de novo coronary artery stenosis: 12-month clinical and imaging outcomes.
Journal of the American College of Cardiology 20111004
-
The magic of disappearing stents.
Journal of the American College of Cardiology 20111004
-
North Central Cancer Treatment Group Phase I trial N057K of everolimus (RAD001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme.
International journal of radiation oncology, biology, physics 20111001
-
Assessment of the serial changes of vessel wall contents in atherosclerotic coronary lesion with bioresorbable everolimus-eluting vascular scaffolds using Shin's method: an IVUS study.
The international journal of cardiovascular imaging 20111001
-
Weekly administration of temsirolimus for heavily pretreated patients with clear cell carcinoma of the ovary: a report of six cases.
International journal of clinical oncology 20111001
-
In vivo therapeutic efficacy of intra-renal CD40 silencing in a model of humoral acute rejection.
Gene therapy 20111001
-
Natural history, management and pharmacokinetics of everolimus-induced-oral ulcers: insights into compliance issues.
European journal of cancer (Oxford, England : 1990) 20111001
-
Evaluation of the effects of the flavonoid apigenin on apoptotic pathway gene expression on the colon cancer cell line (HT29).
Journal of medicinal food 20111001
-
Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells.
Aging cell 20111001
-
Long-term response in advanced bladder cancer involving the use of temsirolimus and vinflunine after platin resistance.
Anti-cancer drugs 20111001
-
Beclin 1-independent autophagy contributes to apoptosis in cortical neurons.
Autophagy 20111001
-
Myxoma virus combined with rapamycin treatment enhances adoptive T cell therapy for murine melanoma brain tumors.
Cancer immunology, immunotherapy : CII 20111001
-
Tissue coverage of a hydrophilic polymer-coated zotarolimus-eluting stent vs. a fluoropolymer-coated everolimus-eluting stent at 13-month follow-up: an optical coherence tomography substudy from the RESOLUTE All Comers trial.
European heart journal 20111001
-
A topical combination of rapamycin and tacrolimus for the treatment of angiofibroma due to tuberous sclerosis complex (TSC): a pilot study of nine Japanese patients with TSC of different disease severity.
The British journal of dermatology 20111001
-
Treatment of facial angiofibromas with topical application of oral rapamycin solution (1mgmL(-1) ) in two patients with tuberous sclerosis.
The British journal of dermatology 20111001
-
Enhanced cellular uptake and in vivo pharmacokinetics of rapamycin-loaded cubic phase nanoparticles for cancer therapy.
Acta biomaterialia 20111001
-
A ticking time bomb?: a case report of very late stent thrombosis more than 2 years after fracture of a Cypher stent.
Clinical research in cardiology : official journal of the German Cardiac Society 20111001
-
Efficacy of re-challenging metastatic renal cell carcinoma with mTOR inhibitors.
Acta oncologica (Stockholm, Sweden) 20111001
-
Phase II trial of the mTOR inhibitor, temsirolimus and evaluation of circulating tumor cells and tumor biomarkers in persistent and recurrent epithelial ovarian and primary peritoneal malignancies: a Gynecologic Oncology Group study.
Gynecologic oncology 20111001
-
Leflunomide with low-dose everolimus for treatment of Kaposi's sarcoma in a renal allograft recipient.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111001
-
Sex differences in neointimal hyperplasia following endeavor zotarolimus-eluting stent implantation.
The American journal of cardiology 20111001
-
Linking molecular feature space and disease terms for the immunosuppressive drug rapamycin.
Molecular bioSystems 20111001
-
In vitro interaction of caspofungin and immunosuppressives against agents of mucormycosis.
The Journal of antimicrobial chemotherapy 20111001
-
Serum levels after everolimus-stent implantation and paclitaxel-balloon angioplasty in an infant with recurrent pulmonary vein obstruction after repaired total anomalous pulmonary venous connection.
Pediatric cardiology 20111001
-
Everolimus tablets for patients with subependymal giant cell astrocytoma.
Expert opinion on pharmacotherapy 20111001
-
Antitumor activity of ridaforolimus and potential cell-cycle determinants of sensitivity in sarcoma and endometrial cancer models.
Molecular cancer therapeutics 20111001
-
Inhibition of protein synthesis by TOR inactivation revealed a conserved regulatory mechanism of the BiP chaperone in Chlamydomonas.
Plant physiology 20111001
-
De-novo calcineurin-inhibitor-free immunosuppression with sirolimus and mycophenolate mofetil after heart transplantation: 5-year results.
Current opinion in organ transplantation 20111001
-
The TEA transcription factor Tec1 links TOR and MAPK pathways to coordinate yeast development.
Genetics 20111001
-
Induction of autophagy with catalytic mTOR inhibitors reduces huntingtin aggregates in a neuronal cell model.
Journal of neurochemistry 20111001
-
mTORC1 activity as a determinant of cancer risk--rationalizing the cancer-preventive effects of adiponectin, metformin, rapamycin, and low-protein vegan diets.
Medical hypotheses 20111001
-
Role of biological targeted therapies in gastroenteropancreatic neuroendocrine tumours.
Endocrine 20111001
-
Clinical presentation and management of mTOR inhibitor-associated stomatitis.
Oral oncology 20111001
-
mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused.
IUBMB life 20111001
-
Evaluation of zotarolimus-eluting metal stent in animal ureters.
Journal of endourology 20111001
-
New target therapies for patients with neuroendocrine tumors of the pancreas.
Expert review of gastroenterology & hepatology 20111001
-
Activation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activation.
Diabetes 20111001
-
[The BASKET-PROVE study].
Giornale italiano di cardiologia (2006) 20111001
-
Vascular response to zotarolimus-coated balloons in injured superficial femoral arteries of the familial hypercholesterolemic Swine.
Circulation. Cardiovascular interventions 20111001
-
Rapamycin induces differentiation of glioma stem/progenitor cells by activating autophagy.
Chinese journal of cancer 20111001
-
ERas enhances resistance to CPT-11 in gastric cancer.
Anticancer research 20111001
-
Sunitinib re-challenge in metastatic renal cell carcinoma treated sequentially with tyrosine kinase inhibitors and everolimus.
Anticancer research 20111001
-
Alemtuzumab preconditioning allows steroid-calcineurin inhibitor-free regimen in live-donor kidney transplant.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20111001
-
A meta-analysis of specifically designed randomized trials of sirolimus-eluting versus paclitaxel-eluting stents in diabetic patients with coronary artery disease.
American heart journal 20111001
-
[Inflammation in tumor progression].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20111001
-
Human peripheral blood CD8+ CD28- T cells of renal allograft recipients do not express FOXP3 protein.
Transplantation proceedings 20111001
-
Long-term clinical and angiographic results of Sirolimus-Eluting Stent in Complex Coronary Chronic Total Occlusion Revascularization: the SECTOR registry.
Journal of interventional cardiology 20111001
-
Erythematous patches and plaques on the chest with induration of the breasts. Metastatic papillary RCC in dermal lymphatics.
Archives of dermatology 20111001
-
Bioresorbable polymeric vascular scaffolds: a cautionary tale.
Circulation. Cardiovascular interventions 20111001
-
Vascular inflammation and repair: implications for re-endothelialization, restenosis, and stent thrombosis.
JACC. Cardiovascular interventions 20111001
-
Assessing the temporal course of neointimal hyperplasia formation after different generations of drug-eluting stents.
JACC. Cardiovascular interventions 20111001
-
Late vascular response following drug-eluting stent implantation.
JACC. Cardiovascular interventions 20111001
-
Comparison of everolimus- and sirolimus-eluting stents in patients with long coronary artery lesions: a randomized LONG-DES-III (Percutaneous Treatment of LONG Native Coronary Lesions With Drug-Eluting Stent-III) Trial.
JACC. Cardiovascular interventions 20111001
-
Comparison of everolimus- and paclitaxel-eluting stents in patients with acute and stable coronary syndromes: pooled results from the SPIRIT (A Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) and COMPARE (A Trial of Everolimus-Eluting Stents and Paclitaxel-Eluting Stents for Coronary Revascularization in Daily Practice) Trials.
JACC. Cardiovascular interventions 20111001
-
Should everolimus-eluting stents be preferred in patients with acute and stable coronary syndromes?
JACC. Cardiovascular interventions 20111001
-
Dual antiplatelet therapy duration and clinical outcomes following treatment with zotarolimus-eluting stents.
JACC. Cardiovascular interventions 20111001
-
Will we ever know the optimal duration of dual antiplatelet therapy after drug-eluting stent implantation?
JACC. Cardiovascular interventions 20111001
-
Three-dimensional reconstruction of the post-dilated ABSORB everolimus-eluting bioresorbable vascular scaffold in a true bifurcation lesion for flow restoration.
JACC. Cardiovascular interventions 20111001
-
Two-year clinical outcomes of patients with long segments drug-eluting stents: comparison of sirolimus-eluting stent with paclitaxel-eluting stent.
Journal of Korean medical science 20111001
-
Comparison of restenosis rate with sirolimus-eluting stent in STEMI patients with and without diabetes at 6-month angiographic follow-up.
Acta cardiologica 20111001
-
Inactivation of mammalian target of rapamycin (mTOR) by rapamycin in a murine model of lipopolysaccharide-induced acute lung injury.
Chinese medical journal 20111001
-
Real world clinical performance of the zotarolimus eluting coronary stent system in Chinese patients: a prospective, multicenter registry study.
Chinese medical journal 20111001
-
Successful pregnancy complicated by persistent pneumothorax in a patient with lymphangioleiomyomatosis (LAM) on sirolimus.
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 20111001
-
[Effects of rapamycin on cholesterol homeostasis and secretory function of 3T3-L1 cells].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20111001
-
Pediatric kidney transplantation followed by de novo therapy with everolimus, low-dose cyclosporine A, and steroid elimination: 3-year data.
Transplantation 20110927
-
RNA polymerase II degradation in response to rapamycin is not mediated through ubiquitylation.
Biochemical and biophysical research communications 20110923
-
Switching heterotrimeric G protein subunits with a chemical dimerizer.
Chemistry & biology 20110923
-
Biodegradable polymer versus permanent polymer drug-eluting stents and everolimus- versus sirolimus-eluting stents in patients with coronary artery disease: 3-year outcomes from a randomized clinical trial.
Journal of the American College of Cardiology 20110920
-
Drug-eluting versus bare-metal stents in saphenous vein graft lesions (ISAR-CABG): a randomised controlled superiority trial.
Lancet (London, England) 20110917
-
Stress-responsive sestrins link p53 with redox regulation and mammalian target of rapamycin signaling.
Antioxidants & redox signaling 20110915
-
Rapamycin enhances the activity of oncolytic herpes simplex virus against tumor cells that are resistant to virus replication.
International journal of cancer 20110915
-
A phase 1 study of everolimus and sorafenib for metastatic clear cell renal cell carcinoma.
Cancer 20110915
-
Limitations in small intestinal neuroendocrine tumor therapy by mTor kinase inhibition reflect growth factor-mediated PI3K feedback loop activation via ERK1/2 and AKT.
Cancer 20110915
-
An updated meta-analysis of randomized controlled trials of everolimus- versus paclitaxel-eluting stents.
International journal of cardiology 20110915
-
Phase I trial of cixutumumab combined with temsirolimus in patients with advanced cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 20110915
-
Using tandem mass spectrometry in targeted mode to identify activators of class IA PI3K in cancer.
Cancer research 20110915
-
Combining EGFR and mTOR blockade for the treatment of epithelioid sarcoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20110915
-
Impact of de novo everolimus-based immunosuppression on incisional complications in heart transplantation.
Transplantation 20110915
-
Erlotinib antagonizes constitutive activation of SRC family kinases and mTOR in acute myeloid leukemia.
Cell cycle (Georgetown, Tex.) 20110915
-
Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors.
Cancer cell 20110913
-
Creating diverse target-binding surfaces on FKBP12: synthesis and evaluation of a rapamycin analogue library.
ACS combinatorial science 20110912
-
Salivary duct carcinoma: targeting the phosphatidylinositol 3-kinase pathway by blocking mammalian target of rapamycin with temsirolimus.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110910
-
BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription.
Blood 20110908
-
Small-molecule-based nanoassemblies as inducible nanoprobes for monitoring dynamic molecular interactions inside live cells.
Angewandte Chemie (International ed. in English) 20110905
-
Acute cholecystitis in a patient with metastatic renal cell carcinoma treated with everolimus.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20110901
-
Exaggerated inflammatory response following sirolimus-eluting stent fracture.
International journal of cardiology 20110901
-
Rapamycin-induced posterior reversible encephalopathy in a kidney transplantation patient.
International urology and nephrology 20110901
-
Optical coherence evaluation of everolimus-eluting stents 8 months after implantation.
Heart (British Cardiac Society) 20110901
-
Combination of everolimus with calcineurin inhibitor medication resulted in post-transplant haemolytic uraemic syndrome in lung transplant recipients--a case series.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110901
-
Combined inhibition of PI3K and mTOR exerts synergistic antiproliferative effect, but diminishes differentiative properties of rapamycin in acute myeloid leukemia cells.
Pathology oncology research : POR 20110901
-
Lymphangioleiomyomatosis treatment with sirolimus.
Archivos de bronconeumologia 20110901
-
Interaction of sirolimus and everolimus with hepatic and intestinal organic anion-transporting polypeptide transporters.
Xenobiotica; the fate of foreign compounds in biological systems 20110901
-
Toxicity spectrum of inhibitors of mammalian target of rapamycin in organ transplantation: etiology, pathogenesis and treatment.
Expert opinion on drug safety 20110901
-
[Metastatic renal cell cancer in Germany in 2010. Impact of different target therapies].
Der Urologe. Ausg. A 20110901
-
Sirolimus demonstrates activity in the primary therapy of acute graft-versus-host disease without systemic glucocorticoids.
Haematologica 20110901
-
Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells.
Haematologica 20110901
-
Intracellular angiotensin II activates rat myometrium.
American journal of physiology. Cell physiology 20110901
-
Sirolimus-eluting stents vs. bare-metal stents for treatment of focal lesions in infrapopliteal arteries: a double-blind, multi-centre, randomized clinical trial.
European heart journal 20110901
-
Assessment of the safety and biodistribution of a regulated AAV2 gene transfer vector after delivery to murine submandibular glands.
Toxicological sciences : an official journal of the Society of Toxicology 20110901
-
New therapeutic options for metastatic malignant insulinomas.
Clinical endocrinology 20110901
-
A combined approach of classical mutagenesis and rational metabolic engineering improves rapamycin biosynthesis and provides insights into methylmalonyl-CoA precursor supply pathway in Streptomyces hygroscopicus ATCC 29253.
Applied microbiology and biotechnology 20110901
-
Paronychia and pyogenic granuloma induced by new anticancer mTOR inhibitors.
Acta dermato-venereologica 20110901
-
Mesenchymal stem cells and carcinoma-associated fibroblasts sensitize breast cancer cells in 3D cultures to kinase inhibitors.
International journal of oncology 20110901
-
Comparison of drug-eluting versus bare metal stents in cardiac allograft vasculopathy.
The American journal of cardiology 20110901
-
Telmisartan reduces neointima volume and pulse wave velocity 8 months after zotarolimus-eluting stent implantation in hypertensive type 2 diabetic patients.
Heart (British Cardiac Society) 20110901
-
The mTOR protein as a target in thyroid cancer.
Expert opinion on therapeutic targets 20110901
-
Features of synergism between mesenchymal stem cells and immunosuppressive drugs in a murine heart transplantation model.
Transplant immunology 20110901
-
Cystogenic potential of CD133+ progenitor cells of human polycystic kidneys.
The Journal of pathology 20110901
-
Percutaneous coronary intervention in Takayasu's arteritis.
International journal of cardiology 20110901
-
Influence of immunosuppressive agents on tryptophan degradation and neopterin production in human peripheral blood mononuclear cells.
Transplant immunology 20110901
-
Role of the AMPK/SREBP-1 pathway in the development of orotic acid-induced fatty liver.
Journal of lipid research 20110901
-
Current management of lymphangioleiomyomatosis.
Current opinion in pulmonary medicine 20110901
-
Sirolimus and growth.
Pediatric transplantation 20110901
-
Identification of novel rapamycin derivatives as low-level impurities in active pharmaceutical ingredients.
The Journal of antibiotics 20110901
-
Influence of low-dose aspirin (81 mg) on the incidence of definite stent thrombosis in patients receiving bare-metal and drug-eluting stents.
Clinical cardiology 20110901
-
Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection.
The Journal of clinical investigation 20110901
-
Randomized trial of immunosuppressive regimens in renal transplantation.
Journal of the American Society of Nephrology : JASN 20110901
-
Managing refractory metastatic renal cell carcinoma: a RECORD spinning on a tilted AXIS.
Clinical genitourinary cancer 20110901
-
Effects of immunosuppressive therapy after experimental small bowel transplantation in rats.
Transplant immunology 20110901
-
Phase I trial of lenalidomide and CCI-779 in patients with relapsed multiple myeloma: evidence for lenalidomide-CCI-779 interaction via P-glycoprotein.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110901
-
Editorial.
Current opinion in pulmonary medicine 20110901
-
Sirolimus for acute pemphigus vulgaris: a case report and discussion of dualistic action providing for both immunosuppression and keratinocyte protection.
Journal of the American Academy of Dermatology 20110901
-
Neuroendocrine regulation of autophagy by leptin.
Cell cycle (Georgetown, Tex.) 20110901
-
The mTOR inhibitor RAD001 sensitizes tumor cells to the cytotoxic effect of carboplatin in breast cancer in vitro.
Anticancer research 20110901
-
Involvement of Akt and mTOR in chemotherapeutic- and hormonal-based drug resistance and response to radiation in breast cancer cells.
Cell cycle (Georgetown, Tex.) 20110901
-
Sirolimus-based immunosuppression for treatment of cutaneous warts in kidney transplant recipients.
Iranian journal of kidney diseases 20110901
-
Graft-versus-host disease therapy: something else beyond glucocorticoids?
Haematologica 20110901
-
Renal carcinoma with (6;11)(p21;q12) translocation: report of an adult case.
Pathology international 20110901
-
Linear growth in pediatric renal transplant recipients receiving sirolimus.
Pediatric transplantation 20110901
-
Persistent dyspnea in a 59-year-old woman receiving immunosuppressants.
Chest 20110901
-
Long-term experience with everolimus in kidney transplantation in the United States.
Transplantation proceedings 20110901
-
A retrospective 12-month study of conversion to everolimus in lung transplant recipients.
Transplantation proceedings 20110901
-
Sirolimus-induced pneumonitis complicated by pentamidine-induced phospholipidosis in a renal transplant recipient: a case report.
Transplantation proceedings 20110901
-
Everolimus and sunitinib: from mouse models to treatment of pancreatic neuroendocrine tumors.
Future oncology (London, England) 20110901
-
IVUS and OCT: either or survivor ….
JACC. Cardiovascular imaging 20110901
-
Hepatocellular carcinoma and liver transplantation: clinical perspective on molecular targeted strategies.
Medical molecular morphology 20110901
-
Three-year outcome of sirolimus-eluting stent implantation in coronary bifurcation lesions: the provisional side branch stenting approach versus the elective two-stent approach.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110901
-
Implantation of the biodegradable polymer biolimus-eluting stent in patients with high SYNTAX score is associated with decreased cardiac mortality compared to a permanent polymer sirolimus-eluting stent: two year follow-up results from the 'all-comers' LEADERS trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110901
-
Bifurcation Optimisation Stent System (BiOSS Lim) with sirolimus elution: results from porcine coronary artery model.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110901
-
Dramatic improvement of facial angiofibromas in tuberous sclerosis with topical rapamycin: optimizing a treatment protocol.
Archives of dermatology 20110901
-
Impact of intravascular ultrasound imaging on early and late clinical outcomes following percutaneous coronary intervention with drug-eluting stents.
JACC. Cardiovascular interventions 20110901
-
Sirolimus-eluting coronary stents in octogenarians: a 1-year analysis of the worldwide e-SELECT Registry.
JACC. Cardiovascular interventions 20110901
-
Serial analysis of the malapposed and uncovered struts of the new generation of everolimus-eluting bioresorbable scaffold with optical coherence tomography.
JACC. Cardiovascular interventions 20110901
-
Total aorto-ostial chronic occlusion of the right coronary artery successfully recanalized via retrograde approach.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110901
-
[Synergistic cytotoxic effects of rapamycin and idarubicin on human acute T-cell lymphoblastic leukemia Jurkat cells].
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20110901
-
The successful management of diffuse lymphangiomatosis using sirolimus: a case report.
The Laryngoscope 20110901
-
[Ryanodine downregulates the expression of p-eNOS (Thr495) and improves the functions of rapamycin treated endothelial outgrowth cells].
Zhonghua xin xue guan bing za zhi 20110901
-
[Basic efficiently of drug eluting stent 2011].
Nihon rinsho. Japanese journal of clinical medicine 20110901
-
[Sirolimis-eluting stent (SES)].
Nihon rinsho. Japanese journal of clinical medicine 20110901
-
[Zotarolimus-eluting stent].
Nihon rinsho. Japanese journal of clinical medicine 20110901
-
[Everolimus-eluting stent].
Nihon rinsho. Japanese journal of clinical medicine 20110901
-
[Biolimus eluting stent].
Nihon rinsho. Japanese journal of clinical medicine 20110901
-
[Effect of RAD001 or plus LBH589 on the proliferation, apoptosis and drug resistance in chemoresistant acute myeloid leukemic cells].
Zhonghua yi xue za zhi 20110830
-
Conversion of long-term kidney transplant recipients from calcineurin inhibitor therapy to everolimus: a randomized, multicenter, 24-month study.
Transplantation 20110827
-
Role of S6K1 in regulation of SREBP1c expression in the liver.
Biochemical and biophysical research communications 20110826
-
Localized ultrasound enhances delivery of rapamycin from microbubbles to prevent smooth muscle proliferation.
Journal of controlled release : official journal of the Controlled Release Society 20110825
-
Safety and efficacy of everolimus, a mTOR inhibitor, as single agent in a phase 1/2 study in patients with myelofibrosis.
Blood 20110825
-
Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4+CD25+Foxp3+ regulatory T cells.
Blood 20110825
-
Randomized comparison of everolimus-eluting stent versus sirolimus-eluting stent implantation for de novo coronary artery disease in patients with diabetes mellitus (ESSENCE-DIABETES): results from the ESSENCE-DIABETES trial.
Circulation 20110823
-
Differential clinical responses to everolimus-eluting and Paclitaxel-eluting coronary stents in patients with and without diabetes mellitus.
Circulation 20110823
-
Is diabetes the achilles' heel of limus-eluting stents?
Circulation 20110823
-
Phase II study of temsirolimus in women with recurrent or metastatic endometrial cancer: a trial of the NCIC Clinical Trials Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110820
-
Sirolimus- vs. paclitaxel-eluting stents for the treatment of unprotected left main coronary artery stenosis: complete 2-year follow-up of a two-center registry.
International journal of cardiology 20110818
-
Regulation of TFEB and V-ATPases by mTORC1.
The EMBO journal 20110817
-
Inhibition of mammalian target of rapamycin signaling by everolimus induces senescence in adult T-cell leukemia/lymphoma and apoptosis in peripheral T-cell lymphomas.
International journal of cancer 20110815
-
Everolimus-eluting versus paclitaxel-eluting stents for treatment of bare metal stent restenosis.
The American journal of cardiology 20110815
-
Therapeutic efficacy of polyclonal tregs does not require rapamycin in a low-dose irradiation bone marrow transplantation model.
Transplantation 20110815
-
Lower malignancy rates in renal allograft recipients converted to sirolimus-based, calcineurin inhibitor-free immunotherapy: 24-month results from the CONVERT trial.
Transplantation 20110815
-
Antagonistic control of muscle cell size by AMPK and mTORC1.
Cell cycle (Georgetown, Tex.) 20110815
-
Everolimus and long-term outcomes in renal transplantation: seeking an optimal strategy for immunosuppression.
Transplantation 20110815
-
Everolimus and long-term outcomes in renal transplantation.
Transplantation 20110815
-
Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110810
-
Polymer-free sirolimus- and probucol-eluting versus new generation zotarolimus-eluting stents in coronary artery disease: the Intracoronary Stenting and Angiographic Results: Test Efficacy of Sirolimus- and Probucol-Eluting versus Zotarolimus-eluting Stents (ISAR-TEST 5) trial.
Circulation 20110802
-
Human herpes virus type 8-associated Kaposi sarcoma in a pediatric liver transplant recipient.
Pediatric transplantation 20110801
-
The mammalian target of rapamycin inhibitor everolimus (RAD001) in early breast cancer: results of a pre-operative study.
Breast cancer research and treatment 20110801
-
Are we missing the mTOR target in breast cancer?
Breast cancer research and treatment 20110801
-
Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis.
Journal of hepatology 20110801
-
A phase 2 study of temsirolimus (CCI-779) in patients with soft tissue sarcomas: a study of the Mayo phase 2 consortium (P2C).
Cancer 20110801
-
The management of subependymal giant cell tumors in tuberous sclerosis: a clinician's perspective.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20110801
-
Oral rapamycin in the treatment of patients with hamartoma syndromes and PTEN mutation.
Pediatric blood & cancer 20110801
-
Conversion to everolimus in maintenance liver transplant patients: a multicenter, retrospective analysis.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20110801
-
Angiographic outcomes with biodegradable polymer and permanent polymer drug-eluting stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110801
-
The influence of co-solvents on the stability and bioavailability of rapamycin formulated in self-microemulsifying drug delivery systems.
Drug development and industrial pharmacy 20110801
-
Low stent thrombosis risk with the XIENCE V® Everolimus-Eluting Coronary Stent: evidence from randomized and single-arm clinical trials.
Journal of interventional cardiology 20110801
-
Cannabinoid receptor agonists modulate oligodendrocyte differentiation by activating PI3K/Akt and the mammalian target of rapamycin (mTOR) pathways.
British journal of pharmacology 20110801
-
FKBPs in chromatin modification and cancer.
Current opinion in pharmacology 20110801
-
Successful treatment of systemic de novo sarcoidosis with cyclosporine discontinuation and provision of rapamune after liver transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20110801
-
A pulse rapamycin therapy for infantile spasms and associated cognitive decline.
Neurobiology of disease 20110801
-
Hepatocyte growth factor-induced c-Src-phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway inhibits dendritic cell activation by blocking IκB kinase activity.
The international journal of biochemistry & cell biology 20110801
-
Subsets of human CD4(+) regulatory T cells express the peripheral homing receptor CXCR3.
European journal of immunology 20110801
-
Focus.
Journal of hepatology 20110801
-
Induction of tolerance to factor VIII by transient co-administration with rapamycin.
Journal of thrombosis and haemostasis : JTH 20110801
-
Sustained targeting of Bcr-Abl + leukemia cells by synergistic action of dual drug loaded nanoparticles and its implication for leukemia therapy.
Biomaterials 20110801
-
Inhibition of the mTOR/p70S6K pathway is not involved in the insulin-sensitizing effect of AMPK on cardiac glucose uptake.
American journal of physiology. Heart and circulatory physiology 20110801
-
A 3-in-1 polymeric micelle nanocontainer for poorly water-soluble drugs.
Molecular pharmaceutics 20110801
-
Modulation of morphogenesis in Candida albicans by various small molecules.
Eukaryotic cell 20110801
-
Cholesterol esters as growth regulators of lymphocytic leukaemia cells.
Cell proliferation 20110801
-
Tilt balance towards regulation: evolving new strategy for treatment of hemophilia inhibitors.
Journal of thrombosis and haemostasis : JTH 20110801
-
First clinical trial of nitinol self-expanding everolimus-eluting stent implantation for peripheral arterial occlusive disease.
Journal of vascular surgery 20110801
-
The ORION study: comparison of two sirolimus-based regimens versus tacrolimus and mycophenolate mofetil in renal allograft recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110801
-
How to use mTOR inhibitors? The search goes on.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110801
-
Rapamycin-induced hypophosphatemia and insulin resistance are associated with mTORC2 activation and Klotho expression.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110801
-
Preclinical characterization of OSI-027, a potent and selective inhibitor of mTORC1 and mTORC2: distinct from rapamycin.
Molecular cancer therapeutics 20110801
-
Direct activation of mTOR in B lymphocytes confers impairment in B-cell maturation andloss of marginal zone B cells.
European journal of immunology 20110801
-
Combinatorial effects of lapatinib and rapamycin in triple-negative breast cancer cells.
Molecular cancer therapeutics 20110801
-
The use of everolimus in pediatric liver transplant recipients: first experience in a single center.
Pediatric transplantation 20110801
-
Sirolimus-eluting stent implantation for ostial left anterior descending coronary artery lesions: three-year outcome from the j-Cypher Registry.
Circulation. Cardiovascular interventions 20110801
-
The mTOR/AKT inhibitor temsirolimus prevents deep infiltrating endometriosis in mice.
The American journal of pathology 20110801
-
Evaluation of the Abbott ARCHITECT i2000 sirolimus assay and comparison with the Abbott IMx sirolimus assay and an established liquid chromatography-tandem mass spectrometry method.
Therapeutic drug monitoring 20110801
-
Evaluation of performance of new, isotopically labeled internal standard ([13c2d4]RAD001) for everolimus using a novel high-performance liquid chromatography tandem mass spectrometry method.
Therapeutic drug monitoring 20110801
-
TORCing up the importance of calcium signaling.
Journal of the American Society of Nephrology : JASN 20110801
-
Skin cancer in solid organ transplant recipients: advances in therapy and management: part I. Epidemiology of skin cancer in solid organ transplant recipients.
Journal of the American Academy of Dermatology 20110801
-
mTor plays an important role in odontoblast differentiation.
Journal of endodontics 20110801
-
mTOR inhibitors in advanced renal cell carcinoma.
Hematology/oncology clinics of North America 20110801
-
Quality of life and targeted treatment for metastatic renal cell carcinoma.
The oncologist 20110801
-
How can we miss you, if you will never leave? Biodegradable stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110801
-
Everolimus-eluting versus sirolimus-eluting stents: a meta-analysis of randomized trials.
Circulation. Cardiovascular interventions 20110801
-
A phase II trial of bevacizumab plus everolimus for patients with refractory metastatic colorectal cancer.
The oncologist 20110801
-
Efficacy and safety of early cyclosporine conversion to sirolimus with continued MMF-four-year results of the Postconcept study.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110801
-
Impact of sirolimus-eluting stent fracture on 4-year clinical outcomes.
Circulation. Cardiovascular interventions 20110801
-
Everolimus vs. rapamycin for treating diabetic nephropathy in diabetic mouse model.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20110801
-
Effects of rapamycin on expression of Bcl-2 and Bax in human lens epithelial cells and cell cycle in rats.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20110801
-
Comparison of six-year clinical outcome of sirolimus- and paclitaxel-eluting stents to bare-metal stents in patients with ST-segment elevation myocardial infarction: an analysis of the RESEARCH (rapamycin-eluting stent evaluated at Rotterdam cardiology hospital) and T-SEARCH (taxus stent evaluated at Rotterdam cardiology hospital) registries.
The Journal of invasive cardiology 20110801
-
Long-term benefit using DES in STEMI patients.
The Journal of invasive cardiology 20110801
-
Rapamycin as an antiaging therapeutic?: targeting mammalian target of rapamycin to treat Hutchinson-Gilford progeria and neurodegenerative diseases.
Rejuvenation research 20110801
-
Meeting report: American Aging Association 40th Annual Meeting, Raleigh, North Carolina, June 3-6, 2011.
Rejuvenation research 20110801
-
2-year clinical follow-up from the randomized comparison of biolimus-eluting stents with biodegradable polymer and sirolimus-eluting stents with durable polymer in routine clinical practice.
JACC. Cardiovascular interventions 20110801
-
Everolimus: an mTOR inhibitor for the treatment of tuberous sclerosis.
Expert review of anticancer therapy 20110801
-
[Rapamycin for myeloid blast crisis in refractory chronic myeloid leukemia with imatinib-resistance].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110801
-
A shining light in the darkness for the treatment of pancreatic neuroendocrine tumors.
Cancer discovery 20110801
-
Use of remote film loading methodology to entrap sirolimus into liposomes: preparation, characterization and in vivo efficacy for treatment of restenosis.
International journal of pharmaceutics 20110729
-
Controlled poly(l-lactide-co-trimethylene carbonate) delivery system of cyclosporine A and rapamycine--the effect of copolymer chain microstructure on drug release rate.
International journal of pharmaceutics 20110729
-
Everolimus for cardiac allograft vasculopathy--every patient, at any time?
Transplantation 20110727
-
Racial variation in the development of posttransplant lymphoproliferative disorders after renal transplantation.
Transplantation 20110727
-
Effect of everolimus introduction on cardiac allograft vasculopathy--results of a randomized, multicenter trial.
Transplantation 20110727
-
[Adverse effects of new oncologic therapies].
Praxis 20110727
-
PIK3CA mutation, but not PTEN loss of function, determines the sensitivity of breast cancer cells to mTOR inhibitory drugs.
Oncogene 20110721
-
Efficacy and safety of sirolimus in lymphangioleiomyomatosis.
The New England journal of medicine 20110721
-
Efficacy and safety of sirolimus in lymphangioleiomyomatosis.
The New England journal of medicine 20110721
-
Phase I study of temsirolimus in pediatric patients with recurrent/refractory solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110720
-
Fighting neurodegeneration with rapamycin: mechanistic insights.
Nature reviews. Neuroscience 20110720
-
The role of autophagy emerging in postinfarction cardiac remodelling.
Cardiovascular research 20110715
-
Transplant-associated thrombotic microangiopathy in pediatric patients treated with sirolimus and tacrolimus.
Pediatric blood & cancer 20110715
-
Effect of pioglitazone on endothelial dysfunction after sirolimus-eluting stent implantation.
The American journal of cardiology 20110715
-
mTORC2 protein complex-mediated Akt (Protein Kinase B) Serine 473 Phosphorylation is not required for Akt1 activity in human platelets [corrected].
The Journal of biological chemistry 20110715
-
CCI-779 inhibits cell-cycle G2-M progression and invasion of castration-resistant prostate cancer via attenuation of UBE2C transcription and mRNA stability.
Cancer research 20110715
-
Inhibiting the mTOR pathway synergistically enhances cytotoxicity in ovarian cancer cells induced by etoposide through upregulation of c-Jun.
Clinical cancer research : an official journal of the American Association for Cancer Research 20110715
-
Insights into ALK-driven cancers revealed through development of novel ALK tyrosine kinase inhibitors.
Cancer research 20110715
-
Everolimus- versus first generation drug-eluting stents: the never-ending story of searching for a winner in the 'limus family'.
International journal of cardiology 20110715
-
The power of chemotherapeutic engineering: arresting cell cycle and suppressing senescence to protect from mitotic inhibitors.
Cell cycle (Georgetown, Tex.) 20110715
-
Stents versus CABG for left main coronary artery disease.
The New England journal of medicine 20110714
-
Stents versus CABG for left main coronary artery disease.
The New England journal of medicine 20110714
-
6-month clinical outcomes following implantation of the bioresorbable everolimus-eluting vascular scaffold in vessels smaller or larger than 2.5 mm.
Journal of the American College of Cardiology 20110712
-
L-threonine regulates G1/S phase transition of mouse embryonic stem cells via PI3K/Akt, MAPKs, and mTORC pathways.
The Journal of biological chemistry 20110708
-
Rapamycin (sirolimus) protects against hypoxic damage in primary heart cultures via Na+/Ca2+ exchanger activation.
Life sciences 20110704
-
Comparison of chronic-stage histopathological findings among 3 coronary stents implanted in the same patient.
International journal of cardiology 20110701
-
Rapamycin synergizes cisplatin sensitivity in basal-like breast cancer cells through up-regulation of p73.
Breast cancer research and treatment 20110701
-
Temporal changes of coronary artery plaque located behind the struts of the everolimus eluting bioresorbable vascular scaffold.
The international journal of cardiovascular imaging 20110701
-
Down-regulation of the ubiquitin-proteasome proteolysis system by amino acids and insulin involves the adenosine monophosphate-activated protein kinase and mammalian target of rapamycin pathways in rat hepatocytes.
Amino acids 20110701
-
Long-term (≥2 years) follow-up optical coherence tomographic study after sirolimus- and paclitaxel-eluting stent implantation: comparison to 9-month follow-up results.
The international journal of cardiovascular imaging 20110701
-
The mTOR pathway affects proliferation and chemosensitivity of urothelial carcinoma cells and is upregulated in a subset of human bladder cancers.
BJU international 20110701
-
mTORC1 activation in childhood ependymoma and response to sirolimus.
Journal of neuro-oncology 20110701
-
Serial angiographic and intravascular ultrasound evaluation to interrogate the presence of late 'catch-up' phenomenon after Cypher® sirolimus-eluting stent implantation.
The international journal of cardiovascular imaging 20110701
-
Long-term outcome after sirolimus-eluting stents versus bare metal stents in patients with diabetes mellitus: a patient-level meta-analysis of randomized trials.
Clinical research in cardiology : official journal of the German Cardiac Society 20110701
-
Twelve-month clinical outcomes of everolimus-eluting stent as compared to paclitaxel- and sirolimus-eluting stent in patients undergoing percutaneous coronary interventions. A meta-analysis of randomized clinical trials.
International journal of cardiology 20110701
-
Percutaneous intervention of a thrombotic-occluded saphenous vein graft successfully treated using the undersized stent approach to prevent distal embolization.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110701
-
An investigator-driven study of everolimus in surgical lung biopsy confirmed idiopathic pulmonary fibrosis.
Respirology (Carlton, Vic.) 20110701
-
Comparison of in vivo acute stent recoil between the bioresorbable everolimus-eluting coronary scaffolds (revision 1.0 and 1.1) and the metallic everolimus-eluting stent.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110701
-
Dual mTORC2/mTORC1 targeting results in potent suppressive effects on acute myeloid leukemia (AML) progenitors.
Clinical cancer research : an official journal of the American Association for Cancer Research 20110701
-
Primum non nocere: safety in clinical trials for IPF.
Respirology (Carlton, Vic.) 20110701
-
A phase I study of sirolimus and bevacizumab in patients with advanced malignancies.
European journal of cancer (Oxford, England : 1990) 20110701
-
Curcumin disrupts uterine leiomyosarcoma cells through AKT-mTOR pathway inhibition.
Gynecologic oncology 20110701
-
Rapamycin inhibits formation of urethral stricture in rabbits.
The Journal of pharmacology and experimental therapeutics 20110701
-
The serine/threonine kinase Pim-2 is a novel anti-apoptotic mediator in myeloma cells.
Leukemia 20110701
-
Rapamycin-sensitive signals control TCR/CD28-driven Ifng, Il4 and Foxp3 transcription and promoter region methylation.
European journal of immunology 20110701
-
Responses to liposomal Doxorubicin, bevacizumab, and temsirolimus in metaplastic carcinoma of the breast: biologic rationale and implications for stem-cell research in breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110701
-
Relapse of aplastic anemia responsive to sirolimus combined with cyclosporine.
Pediatric blood & cancer 20110701
-
Meta-analysis of everolimus-eluting stent as compared to sirolimus-eluting stent in patients undergoing percutaneous coronary interventions: an update.
International journal of cardiology 20110701
-
Starvation and rapamycin differentially regulate host cell lysosome exocytosis and invasion by Trypanosoma cruzi metacyclic forms.
Cellular microbiology 20110701
-
mTORC1 inhibition increases neurotensin secretion and gene expression through activation of the MEK/ERK/c-Jun pathway in the human endocrine cell line BON.
American journal of physiology. Cell physiology 20110701
-
Inhibition of mTOR by temsirolimus contributes to prolonged survival of mice with pleural dissemination of non-small-cell lung cancer cells.
Cancer science 20110701
-
Phase I trial of capecitabine plus everolimus (RAD001) in patients with previously treated metastatic gastric cancer.
Cancer chemotherapy and pharmacology 20110701
-
CD4(+)CD25(high)CD127(low) regulatory T cells in patients with stable angina and their dynamics after intracoronary sirolimus-eluting stent implantation.
Human immunology 20110701
-
Continuing response to subsequent treatment lines with tyrosine kinase inhibitors in an adolescent with metastatic renal cell carcinoma.
Journal of pediatric hematology/oncology 20110701
-
Rheb/mTOR activation and regulation in cancer: novel treatment strategies beyond rapamycin.
Current drug targets 20110701
-
Role of ROS in the protective effect of silibinin on sodium nitroprusside-induced apoptosis in rat pheochromocytoma PC12 cells.
Free radical research 20110701
-
High-throughput LC-MS/MS method for monitoring sirolimus and everolimus in the routine clinical laboratory.
Clinical chemistry and laboratory medicine 20110701
-
Rapamycin partially mimics the anticancer effects of calorie restriction in a murine model of pancreatic cancer.
Cancer prevention research (Philadelphia, Pa.) 20110701
-
Rapamycin-conditioned, alloantigen-pulsed myeloid dendritic cells present donor MHC class I/peptide via the semi-direct pathway and inhibit survival of antigen-specific CD8(+) T cells in vitro and in vivo.
Transplant immunology 20110701
-
An adjusted indirect comparison of everolimus and sorafenib therapy in sunitinib-refractory metastatic renal cell carcinoma patients using repeated matched samples.
Expert opinion on pharmacotherapy 20110701
-
Involvement of 4E-BP phosphorylation in embryonic development of the silkworm, Bombyx mori.
Journal of insect physiology 20110701
-
Combination of PI3K/mTOR inhibitors: antitumor activity and molecular correlates.
Cancer research 20110701
-
Restenosis after implantation of sirolimus-eluting stent begins suddenly, shows short term progression, and stops suddenly.
Journal of cardiology 20110701
-
The activity of trabectedin as a single agent or in combination with everolimus for clear cell carcinoma of the ovary.
Clinical cancer research : an official journal of the American Association for Cancer Research 20110701
-
S6 kinase 1 is required for rapamycin-sensitive liver proliferation after mouse hepatectomy.
The Journal of clinical investigation 20110701
-
mTOR and the differentiation of mesenchymal stem cells.
Acta biochimica et biophysica Sinica 20110701
-
Temsirolimus and bevacizumab, or sunitinib, or interferon alfa and bevacizumab for patients with advanced renal cell carcinoma (TORAVA): a randomised phase 2 trial.
The Lancet. Oncology 20110701
-
Combination therapy in metastatic renal cell carcinoma.
The Lancet. Oncology 20110701
-
Structural identification of SAR-943 metabolites generated by human liver microsomes in vitro using mass spectrometry in combination with analysis of fragmentation patterns.
Journal of mass spectrometry : JMS 20110701
-
Modulation of autophagy influences development and apoptosis in mouse embryos developing in vitro.
Molecular reproduction and development 20110701
-
Testing the strength of biodegradable stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110701
-
Cost-effectiveness of drug-eluting stents versus bare metal stents in clinical practice.
Circulation. Cardiovascular quality and outcomes 20110701
-
[Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma].
Aktuelle Urologie 20110701
-
[The influence of rapamycin on BTLA expression of human peripheral blood T lymphocytes].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20110701
-
Monitoring ketamine treatment response in a depressed patient via peripheral mammalian target of rapamycin activation.
The American journal of psychiatry 20110701
-
Successful stent implantation guided by intravascular ultrasound and a Doppler guidewire without contrast injection in a patient with allergy to iodinated contrast media.
The Journal of invasive cardiology 20110701
-
Transient coronary aneurysm formation after Nevoâ„¢ stent implantation versus persistent coronary aneurysm after Cypher Selectâ„¢ stent implantation.
The Journal of invasive cardiology 20110701
-
Local delivery of rapamycin: a toxicity and efficacy study in an experimental malignant glioma model in rats.
Neuro-oncology 20110701
-
Should stent selection in diabetic patients be considered as a special case?
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110701
-
Clinical and angiographic outcomes of elderly patients treated with everolimus-eluting versus paclitaxel-eluting stents: three-year results from the SPIRIT III randomised trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110701
-
Late lumen loss and intima hyperplasia after sirolimus-eluting and zotarolimus-eluting stent implantation in diabetic patients: the diabetes and drug-eluting stent (DiabeDES III) angiography and intravascular ultrasound trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110701
-
Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy.
Oncotarget 20110701
-
Ridaforolimus: a promising drug in the treatment of soft-tissue sarcoma and other malignancies.
Future oncology (London, England) 20110701
-
Rapamycin is a potent inhibitor of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Cancer prevention research (Philadelphia, Pa.) 20110701
-
Changes in reference vessel diameter in ST-segment elevation myocardial infarction after primary percutaneous coronary intervention: implications for appropriate stent sizing.
American heart journal 20110701
-
Progeria, rapamycin and normal aging: recent breakthrough.
Aging 20110701
-
Impact of drug release kinetics on vascular response to different zotarolimus-eluting stents implanted in patients with long coronary stenoses: the LongOCT study (Optical Coherence Tomography in Long Lesions).
JACC. Cardiovascular interventions 20110701
-
Linking drug-eluting stent kinetics and clinical outcomes: insights from optical coherence tomography.
JACC. Cardiovascular interventions 20110701
-
Development of a biodegradable sirolimus-eluting stent coated by ultrasonic atomizing spray.
Journal of nanoscience and nanotechnology 20110701
-
An increase in basal BDNF provokes hyperactivation of the Akt-mammalian target of rapamycin pathway and deregulation of local dendritic translation in a mouse model of Down's syndrome.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20110629
-
Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells.
Science translational medicine 20110629
-
2-year follow-up of a randomized controlled trial of everolimus- and paclitaxel-eluting stents for coronary revascularization in daily practice. COMPARE (Comparison of the everolimus eluting XIENCE-V stent with the paclitaxel eluting TAXUS LIBERTÉ stent in all-comers: a randomized open label trial).
Journal of the American College of Cardiology 20110628
-
Randomized comparison of everolimus- and paclitaxel-eluting stents. 2-year follow-up from the SPIRIT (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) IV trial.
Journal of the American College of Cardiology 20110628
-
Second-generation drug-eluting stents. Moving the field forward.
Journal of the American College of Cardiology 20110628
-
Tacrolimus and sirolimus induce reproductive abnormalities in female rats.
Transplantation 20110627
-
Five-year outcomes of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: are they equally good (or bad)?
Circulation 20110621
-
Five-year clinical and angiographic outcomes of a randomized comparison of sirolimus-eluting and paclitaxel-eluting stents: results of the Sirolimus-Eluting Versus Paclitaxel-Eluting Stents for Coronary Revascularization LATE trial.
Circulation 20110621
-
Summaries for patients. Sirolimus therapy in patients with lymphangioleiomyomatosis.
Annals of internal medicine 20110621
-
Changes in lung function and chylous effusions in patients with lymphangioleiomyomatosis treated with sirolimus.
Annals of internal medicine 20110621
-
Tuberous sclerosis complex and lymphangioleiomyomatosis: miles to go, promises to keep.
Annals of internal medicine 20110621
-
Mammalian target of rapamycin: a central node of complex signaling cascades.
International journal of clinical and experimental pathology 20110620
-
A proof of concept phase II non-inferiority criterion.
Statistics in medicine 20110615
-
Outcomes after unrestricted use of everolimus-eluting stent compared to paclitaxel- and sirolimus-eluting stents.
The American journal of cardiology 20110615
-
Sirolimus therapy for angiomyolipoma in tuberous sclerosis and sporadic lymphangioleiomyomatosis: a phase 2 trial.
Clinical cancer research : an official journal of the American Association for Cancer Research 20110615
-
Comparison of everolimus-eluting stent with paclitaxel-eluting stent in long chronic total occlusions.
The American journal of cardiology 20110615
-
mTOR kinase inhibitor AZD8055 enhances the immunotherapeutic activity of an agonist CD40 antibody in cancer treatment.
Cancer research 20110615
-
Persistent long-term synaptic plasticity requires activation of a new signaling pathway by additional stimuli.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20110615
-
Intestinal absorption and intestinal lymphatic transport of sirolimus from self-microemulsifying drug delivery systems assessed using the single-pass intestinal perfusion (SPIP) technique and a chylomicron flow blocking approach: linear correlation with oral bioavailabilities in rats.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110614
-
[Role of rapamycin in cholangiocytes regeneration after liver transplantation].
Zhonghua yi xue za zhi 20110614
-
Cell signaling. New mTOR targets Grb attention.
Science (New York, N.Y.) 20110610
-
The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.
Science (New York, N.Y.) 20110610
-
Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling.
Science (New York, N.Y.) 20110610
-
Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling.
Cell metabolism 20110608
-
Late asymptomatic sirolimus-eluting stent fracture in a female with systemic lupus erythematosus.
International journal of cardiology 20110602
-
Leucine promotes leptin receptor expression in mouse C2C12 myotubes through the mTOR pathway.
Molecular biology reports 20110601
-
Thrombotic thrombocytopenic purpura associated with everolimus use in a renal transplant patient.
International urology and nephrology 20110601
-
The selective VEGFR1-3 inhibitor axitinib (AG-013736) shows antitumor activity in human neuroblastoma xenografts.
International journal of cancer 20110601
-
Retinoic acid induces autophagosome maturation through redistribution of the cation-independent mannose-6-phosphate receptor.
Antioxidants & redox signaling 20110601
-
Four-year clinical follow-up of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with de novo coronary artery lesions: the SPIRIT II trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110601
-
Extended follow-up safety and effectiveness of the Endeavor zotarolimus-eluting stent in real-world clinical practice: two-year follow-up from the E-Five Registry.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110601
-
Prophylaxis with sirolimus and tacrolimus ± antithymocyte globulin reduces the risk of acute graft-versus-host disease without an overall survival benefit following allogeneic stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110601
-
Donor pre-treatment with everolimus or cyclosporine does not reduce ischaemia-reperfusion injury in a rat kidney transplant model.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110601
-
Decrease in transient receptor potential melastatin 6 mRNA stability caused by rapamycin in renal tubular epithelial cells.
Biochimica et biophysica acta 20110601
-
Expansion of CD4(+)CD25 (+) regulatory T cells from cord blood CD4(+) cells using the common γ-chain cytokines (IL-2 and IL-15) and rapamycin.
Annals of hematology 20110601
-
Clinical and molecular insights into tuberous sclerosis complex renal disease.
Pediatric nephrology (Berlin, Germany) 20110601
-
Endothelium-dependent coronary vasomotor response and neointimal coverage of zotarolimus-eluting stents 3 months after implantation.
Heart (British Cardiac Society) 20110601
-
Poly(ethylene glycol)-block-poly(2-methyl-2-benzoxycarbonyl-propylene carbonate) micelles for rapamycin delivery: in vitro characterization and biodistribution.
Journal of pharmaceutical sciences 20110601
-
Recent developments in drug-eluting stents.
Journal of molecular medicine (Berlin, Germany) 20110601
-
Temsirolimus in advanced leiomyosarcomas: patterns of response and correlation with the activation of the mammalian target of rapamycin pathway.
Anti-cancer drugs 20110601
-
Targeting glycolysis in leukemia: a novel inhibitor 3-BrOP in combination with rapamycin.
Leukemia research 20110601
-
PDGF-induced vascular smooth muscle cell proliferation is associated with dysregulation of insulin receptor substrates.
American journal of physiology. Cell physiology 20110601
-
Five-year experience using sirolimus-based, calcineurin inhibitor-free immunosuppression in pediatric renal transplantation.
Pediatric transplantation 20110601
-
Growth of kidney-transplanted pediatric patients treated with sirolimus.
Pediatric nephrology (Berlin, Germany) 20110601
-
Efficacy of ganitumab (AMG 479), alone and in combination with rapamycin, in Ewing's and osteogenic sarcoma models.
The Journal of pharmacology and experimental therapeutics 20110601
-
Complete induction of autophagy is essential for cardioprotection in sepsis.
Annals of surgery 20110601
-
Dramatic tumor response to everolimus for malignant epithelioid angiomyolipoma.
Japanese journal of clinical oncology 20110601
-
mTOR complex 2 activation by reconstituted high-density lipoprotein prevents senescence in circulating angiogenic cells.
Arteriosclerosis, thrombosis, and vascular biology 20110601
-
Autophagy protects against aminochrome-induced cell death in substantia nigra-derived cell line.
Toxicological sciences : an official journal of the Society of Toxicology 20110601
-
mTOR inhibition, a potential novel approach for bronchial carcinoids.
Endocrine-related cancer 20110601
-
The real world experience of the everolimus-eluting coronary stent system: audit of everolimus-eluting coronary stents.
Journal of interventional cardiology 20110601
-
Effects of rapamycin and TOR on aging and memory: implications for Alzheimer's disease.
Journal of neurochemistry 20110601
-
[Collecting duct renal cell carcinoma].
Actas urologicas espanolas 20110601
-
Impact of combined HDAC and mTOR inhibition on adhesion, migration and invasion of prostate cancer cells.
Clinical & experimental metastasis 20110601
-
Adiponectin induces vascular smooth muscle cell differentiation via repression of mammalian target of rapamycin complex 1 and FoxO4.
Arteriosclerosis, thrombosis, and vascular biology 20110601
-
The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells.
Cancer biology & therapy 20110601
-
Mammalian target of rapamycin expression in poorly differentiated endocrine carcinoma: clinical and therapeutic future challenges.
Targeted oncology 20110601
-
Acid β-glucosidase mutants linked to Gaucher disease, Parkinson disease, and Lewy body dementia alter α-synuclein processing.
Annals of neurology 20110601
-
Treatment of metastatic renal cell carcinoma and renal pelvic cancer.
Clinical and experimental nephrology 20110601
-
Management of adverse events associated with the use of everolimus in patients with advanced renal cell carcinoma.
European journal of cancer (Oxford, England : 1990) 20110601
-
Impaired autophagy: a link between neurodegenerative diseases and progressive myoclonus epilepsies.
Trends in molecular medicine 20110601
-
Everolimus induces rapid plasma glucose normalization in insulinoma patients by effects on tumor as well as normal tissues.
The oncologist 20110601
-
Ridaforolimus (AP23573; MK-8669), a potent mTOR inhibitor, has broad antitumor activity and can be optimally administered using intermittent dosing regimens.
Molecular cancer therapeutics 20110601
-
Everolimus augments the effects of sorafenib in a syngeneic orthotopic model of hepatocellular carcinoma.
Molecular cancer therapeutics 20110601
-
An intein-cassette integration approach used for the generation of a split TEV protease activated by conditional protein splicing.
Molecular bioSystems 20110601
-
Chemotherapy-related bilateral dermatitis associated with eccrine squamous syringometaplasia: reappraisal of epidemiological, clinical, and pathological features.
Journal of the American Academy of Dermatology 20110601
-
Common toxicities of mammalian target of rapamycin inhibitors.
Targeted oncology 20110601
-
Bone healing after secondary surgery on hand allografts under sirolimus-based maintenance immunosuppression.
Annals of plastic surgery 20110601
-
Predictive biomarkers for the activity of mammalian target of rapamycin (mTOR) inhibitors.
Targeted oncology 20110601
-
Long-term outcomes of sirolimus-eluting stents vs. paclitaxel-eluting stents in unprotected left main coronary artery bifurcation lesions.
Clinical cardiology 20110601
-
Clinical activity of mammalian target of rapamycin inhibitors in solid tumors.
Targeted oncology 20110601
-
Targeting phosphatidylinositol 3 kinase (PI3K)-Akt beyond rapalogs.
Targeted oncology 20110601
-
Generation and large-scale expansion of human inducible regulatory T cells that suppress graft-versus-host disease.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110601
-
mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry.
Genes & development 20110601
-
Impact of polymer formulations on neointimal proliferation after zotarolimus-eluting stent with different polymers: insights from the RESOLUTE trial.
Circulation. Cardiovascular interventions 20110601
-
The role of sirolimus in the prevention of cutaneous squamous cell carcinoma in organ transplant recipients.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20110601
-
Role of mTOR in podocyte function and diabetic nephropathy in humans and mice.
The Journal of clinical investigation 20110601
-
mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.
The Journal of clinical investigation 20110601
-
The targeted podocyte.
The Journal of clinical investigation 20110601
-
Hypoxia-induced ROS signaling is required for LOX up-regulation in endothelial cells.
Frontiers in bioscience (Elite edition) 20110601
-
Sirolimus: not so sparing in the Spare-the-Nephron trial.
Kidney international 20110601
-
Temsirolimus in relapsed and/or refractory mantle cell lymphoma†: profile report.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20110601
-
Posttransplant distal limb syndrome.
The Journal of orthopaedic and sports physical therapy 20110601
-
No role for early IGF-1 signalling in stimulating acute 'muscle building' responses.
The Journal of physiology 20110601
-
The isomerase Rrd1 mediates rapid loss of the Sgs1 helicase in response to rapamycin.
Biochemistry and cell biology = Biochimie et biologie cellulaire 20110601
-
The possibility of delayed arterial healing 5 years after implantation of sirolimus-eluting stents: serial observations by coronary angioscopy.
American heart journal 20110601
-
Aberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling.
The American journal of pathology 20110601
-
Are we ready to move away from nature?: the rapamycin story.
Targeted oncology 20110601
-
Enhanced efficacy of sirolimus-eluting bioabsorbable magnesium alloy stents in the prevention of restenosis.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20110601
-
Commentary: Deliver the drug and disappear: is the bioabsorbable magnesium stent growing up or still shrinking?
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20110601
-
Sirolimus therapy predisposes to new-onset diabetes mellitus after renal transplantation: a long-term analysis of various treatment regimens.
Transplantation proceedings 20110601
-
Vascular endothelial function of sirolimus maintenance regimen in renal transplant recipients.
Transplantation proceedings 20110601
-
Laparoscopic incisional hernia repair after solid-organ transplantation.
Transplantation proceedings 20110601
-
Everolimus plus dosage reduction of cyclosporine in cardiac transplant recipients with chronic kidney disease: a two-year follow-up study.
Transplantation proceedings 20110601
-
Calcineurin inhibitor-free immunosuppression using everolimus (Certican) after heart transplantation: 2 years' follow-up from the University Hospital Münster.
Transplantation proceedings 20110601
-
Efficacy and safety of sirolimus and everolimus in heart transplant patients: a retrospective analysis.
Transplantation proceedings 20110601
-
Long-term maintenance therapy for post-cardiac transplant monoclonal lymphoproliferative disorder: caveat mammalian target of rapamycin.
Transplantation proceedings 20110601
-
Local application of rapamycin inhibits vein graft restenosis in rabbits.
Transplantation proceedings 20110601
-
Comparison of titanium-nitride-oxide-coated stents with zotarolimus-eluting stents for coronary revascularization a randomized controlled trial.
JACC. Cardiovascular interventions 20110601
-
Paclitaxel-eluting balloons for sirolimus-eluting stent restenosis.
JACC. Cardiovascular interventions 20110601
-
In-stent restenosis after revascularization of myocardium with drug-eluting stents is accompanied by elevated level of blood plasma eosinophil cationic protein.
Canadian journal of physiology and pharmacology 20110601
-
Incidence, risk factors, and clinical sequelae of angiographic peri-stent contrast staining after sirolimus-eluting stent implantation.
Circulation 20110531
-
The impact of patient and lesion complexity on clinical and angiographic outcomes after revascularization with zotarolimus- and everolimus-eluting stents: a substudy of the RESOLUTE All Comers Trial (a randomized comparison of a zotarolimus-eluting stent with an everolimus-eluting stent for percutaneous coronary intervention).
Journal of the American College of Cardiology 20110531
-
Hormonally active vitamin D3 (1alpha,25-dihydroxycholecalciferol) triggers autophagy in human macrophages that inhibits HIV-1 infection.
The Journal of biological chemistry 20110527
-
Prospective study of everolimus with calcineurin inhibitor-free immunosuppression in maintenance heart transplant patients: results at 2 years.
Transplantation 20110527
-
Everolimus and minimization of cyclosporine in renal transplantation: 24-month follow-up of the EVEREST study.
Transplantation 20110527
-
Genetic and clinical risk factors of new-onset diabetes after transplantation in Hispanic kidney transplant recipients.
Transplantation 20110527
-
Long-term comparison of everolimus-eluting and sirolimus-eluting stents for coronary revascularization.
Journal of the American College of Cardiology 20110524
-
Akt/mammalian target of rapamycin signaling pathway regulates neurite outgrowth in cerebellar granule neurons stimulated by methylcobalamin.
Neuroscience letters 20110520
-
The long and winding road to rational treatment of cancer associated with LKB1/AMPK/TSC/mTORC1 signaling.
Oncogene 20110519
-
Combination of direct and adjusted indirect comparisons of sirolimus- versus paclitaxel-eluting stents for ST-segment elevation myocardial infarction.
International journal of cardiology 20110519
-
[Effects of sirolimus upon endothelial thrombotic function of human umbilical vein endothelial cells].
Zhonghua yi xue za zhi 20110517
-
Targeting the JNK signaling pathway potentiates the antiproliferative efficacy of rapamycin in LS174T colon cancer cells.
The Journal of surgical research 20110515
-
Sirolimus and proteinuria in renal transplant patients: evidence for a dose-dependent effect on slit diaphragm-associated proteins.
Transplantation 20110515
-
Successful pregnancy in a living-related kidney transplant recipient who received sirolimus throughout the whole gestation.
Transplantation 20110515
-
Advances in pancreatic neuroendocrine tumor treatment.
The New England journal of medicine 20110512
-
Everolimus- and temsirolimus-associated enteritis: report of three cases.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110510
-
Phosphomimetic substitution of heterogeneous nuclear ribonucleoprotein A1 at serine 199 abolishes AKT-dependent internal ribosome entry site-transacting factor (ITAF) function via effects on strand annealing and results in mammalian target of rapamycin complex 1 (mTORC1) inhibitor sensitivity.
The Journal of biological chemistry 20110506
-
Randomized trial of stents versus bypass surgery for left main coronary artery disease.
The New England journal of medicine 20110505
-
Everolimus interferes with the inflammatory phase of healing in experimental colonic anastomoses.
The Journal of surgical research 20110501
-
Biodegradable sirolimus-loaded poly(lactide) nanoparticles as drug delivery system for the prevention of in-stent restenosis in coronary stent application.
Journal of biomaterials applications 20110501
-
Rapamycin suppresses ROS-dependent apoptosis caused by selenomethionine in A549 lung carcinoma cells.
Cancer chemotherapy and pharmacology 20110501
-
Therapy of sclerodermatous chronic graft-versus-host disease with mammalian target of rapamycin inhibitors.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110501
-
Double umbilical cord blood transplantation with reduced intensity conditioning and sirolimus-based GVHD prophylaxis.
Bone marrow transplantation 20110501
-
Strategies to prevent EBV reactivation and posttransplant lymphoproliferative disorders (PTLD) after allogeneic stem cell transplantation in high-risk patients.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110501
-
Evaluation of sphingolipid metabolism in renal cortex of rats with streptozotocin-induced diabetes and the effects of rapamycin.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110501
-
The 5352 A allele of the pro-inflammatory caspase-1 gene predicts late-acquired stent malapposition in STEMI patients treated with sirolimus stents.
Heart and vessels 20110501
-
Adoptive transfer of CD4+CD25+ regulatory cells combined with low-dose sirolimus and anti-thymocyte globulin delays acute rejection of renal allografts in Cynomolgus monkeys.
International immunopharmacology 20110501
-
Generation of human regulatory T cells de novo with suppressive function prevent xenogeneic graft versus host disease.
International immunopharmacology 20110501
-
Somatostatin analogues for treatment of polycystic liver disease.
Current opinion in gastroenterology 20110501
-
Predictors of long-term renal function after conversion to proliferation signal inhibitors in long-term heart transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20110501
-
GSK3β inactivation in podocytes results in decreased phosphorylation of p70S6K accompanied by cytoskeletal rearrangements and inhibited motility.
American journal of physiology. Renal physiology 20110501
-
Differential effects of rapamycin on rods and cones during light-induced stress in albino mice.
Investigative ophthalmology & visual science 20110501
-
Costimulatory blockade with mTor inhibition abrogates effector T-cell responses allowing regulatory T-cell survival in renal transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20110501
-
Visfatin exerts angiogenic effects on human umbilical vein endothelial cells through the mTOR signaling pathway.
Biochimica et biophysica acta 20110501
-
Targeted inhibition of mTORC1 and mTORC2 by active-site mTOR inhibitors has cytotoxic effects in T-cell acute lymphoblastic leukemia.
Leukemia 20110501
-
Lack of compensatory pAKT activation and eIF4E phosphorylation of lymphoma cells towards mTOR inhibitor, RAD001.
European journal of cancer (Oxford, England : 1990) 20110501
-
Rapamycin treatment augments both protein ubiquitination and Akt activation in pressure-overloaded rat myocardium.
American journal of physiology. Heart and circulatory physiology 20110501
-
Rapamycin inhibits hydrogen peroxide-induced loss of vascular contractility.
American journal of physiology. Heart and circulatory physiology 20110501
-
Temsirolimus inhibits malignant pleural mesothelioma growth in vitro and in vivo: synergism with chemotherapy.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110501
-
AMPK and substrate availability regulate creatine transport in cultured cardiomyocytes.
American journal of physiology. Endocrinology and metabolism 20110501
-
The antagonist of the JAK-1/STAT-1 signaling pathway improves the severity of cerulein-stimulated pancreatic injury via inhibition of NF-κB activity.
International journal of molecular medicine 20110501
-
Five-year clinical follow-up after sirolimus-eluting stent implantation for the treatment of coronary in-stent restenosis.
Coronary artery disease 20110501
-
Effects of mTOR inhibitor everolimus (RAD001) on bladder cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 20110501
-
The mTOR-targeting drug temsirolimus enhances the growth-inhibiting effects of the cetuximab-bevacizumab-irradiation combination on head and neck cancer xenografts.
Oral oncology 20110501
-
The potential benefits and risks of the use of dual antiplatelet therapy beyond 6 months following sirolimus-eluting stent implantation for low-risk patients.
Journal of cardiology 20110501
-
Drug-related pneumonitis in patients with advanced renal cell carcinoma treated with temsirolimus.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110501
-
Patient-reported outcomes in a phase iii study of everolimus versus placebo in patients with metastatic carcinoma of the kidney that has progressed on vascular endothelial growth factor receptor tyrosine kinase inhibitor therapy.
The oncologist 20110501
-
Secreted factors from brain endothelial cells maintain glioblastoma stem-like cell expansion through the mTOR pathway.
EMBO reports 20110501
-
Regression of a cardiac rhabdomyoma in a patient receiving everolimus.
Pediatrics 20110501
-
Clinical outcomes by geographic region for patients implanted with the zotarolimus-eluting stent.
Arquivos brasileiros de cardiologia 20110501
-
Everolimus for the treatment of advanced renal cell carcinoma.
Expert opinion on pharmacotherapy 20110501
-
The cutaneous effects of post-transplant immunosuppression with cyclosporine in Muir-Torre syndrome.
Journal of the American Academy of Dermatology 20110501
-
Efficacy and comparative effectiveness of sirolimus as an anticancer drug.
The Laryngoscope 20110501
-
CD40-specific costimulation blockade enhances neonatal porcine islet survival in nonhuman primates.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110501
-
Ex vivo transfer of adenovirus-mediated CTLA4Ig gene combined with a short course of rapamycin therapy prolongs free flap allograft survival.
Plastic and reconstructive surgery 20110501
-
Rapamycin-loaded nanoparticles for inhibition of neointimal hyperplasia in experimental vein grafts.
Annals of vascular surgery 20110501
-
Predictors of death or myocardial infarction, ischaemic-driven revascularisation, and major adverse cardiovascular events following everolimus-eluting or paclitaxel-eluting stent deployment: pooled analysis from the SPIRIT II, III, IV and COMPARE trials.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501
-
PLATINUM QCA: a prospective, multicentre study assessing clinical, angiographic, and intravascular ultrasound outcomes with the novel platinum chromium thin-strut PROMUS Element everolimus-eluting stent in de novo coronary stenoses.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501
-
Impact of drug-eluting stent type on periprocedural myocardial necrosis.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501
-
Rationale and design of the clinical evaluation of the Resolute Zotarolimus-Eluting Coronary Stent System in the treatment of de novo lesions in native coronary arteries (the RESOLUTE US clinical trial).
American heart journal 20110501
-
Late-term clinical outcomes with zotarolimus- and sirolimus-eluting stents. 5-year follow-up of the ENDEAVOR III (A Randomized Controlled Trial of the Medtronic Endeavor Drug [ABT-578] Eluting Coronary Stent System Versus the Cypher Sirolimus-Eluting Coronary Stent System in De Novo Native Coronary Artery Lesions).
JACC. Cardiovascular interventions 20110501
-
My stent is better than your stent...Or is it?
JACC. Cardiovascular interventions 20110501
-
Usefulness of rotational atherectomy in preventing polymer damage of everolimus-eluting stent in calcified coronary artery.
JACC. Cardiovascular interventions 20110501
-
Experimental study of the anticancer effect of gemcitabine combined with sirolimus on chemically induced urothelial lesions.
Anticancer research 20110501
-
Once-a-day administration of everolimus is safe in de novo renal transplant recipients: 1-year results of a pilot study.
Transplantation proceedings 20110501
-
University of Modena experience in HIV-positive patients undergoing liver transplantation.
Transplantation proceedings 20110501
-
Causes of sirolimus discontinuation in 97 liver transplant recipients.
Transplantation proceedings 20110501
-
Incisional hernia after simultaneous pancreas kidney tranplantation: a single-center experience from Budapest.
Transplantation proceedings 20110501
-
Coactivation of receptor tyrosine kinases in malignant mesothelioma as a rationale for combination targeted therapy.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110501
-
Optical coherence tomography (OCT) in PCI for in-stent restenosis (ISR): rationale and design of the SEDUCE (Safety and Efficacy of a Drug elUting balloon in Coronary artery rEstenosis) study.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501
-
Local drug delivery - the early Berlin experience: single drug administration versus sustained release.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501
-
Paclitaxel and sirolimus differentially affect growth and motility of endothelial progenitor cells and coronary artery smooth muscle cells.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501
-
A prospective randomised study using optical coherence tomography to assess endothelial coverage and neointimal proliferation at 6-months after implantation of a coronary everolimus-eluting stent compared with a bare metal stent postdilated with a paclitaxel-eluting balloon (OCTOPUS Trial): rationale, design and methods.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501
-
Patient organizations and research on rare diseases.
The New England journal of medicine 20110428
-
Efficacy and safety of sirolimus in lymphangioleiomyomatosis.
The New England journal of medicine 20110428
-
Clinical evaluation of the Resolute zotarolimus-eluting coronary stent system in the treatment of de novo lesions in native coronary arteries: the RESOLUTE US clinical trial.
Journal of the American College of Cardiology 20110426
-
Isolation and structure of homotemsirolimuses A, B, and C.
Journal of natural products 20110425
-
[Novelties in the treatment for advanced renal-cell cancer].
Orvosi hetilap 20110424
-
The inhibition of MAPK potentiates the anti-angiogenic efficacy of mTOR inhibitors.
Biochemical and biophysical research communications 20110422
-
Inhibition of mTOR blocks the anti-inflammatory effects of glucocorticoids in myeloid immune cells.
Blood 20110421
-
Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection.
Cell host & microbe 20110421
-
Response of lymphangioleiomyomatosis to a mammalian target of rapamycin inhibitor (temsirolimus) -based treatment.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110420
-
Recent studies show promise for treating rare pancreatic tumors.
Journal of the National Cancer Institute 20110420
-
A prospective, randomized evaluation of a novel everolimus-eluting coronary stent: the PLATINUM (a Prospective, Randomized, Multicenter Trial to Assess an Everolimus-Eluting Coronary Stent System [PROMUS Element] for the Treatment of Up to Two de Novo Coronary Artery Lesions) trial.
Journal of the American College of Cardiology 20110419
-
Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure.
Biological psychiatry 20110415
-
Comparison of three-year clinical outcomes after sirolimus-eluting stent implantation among insulin-treated diabetic, non-insulin-treated diabetic, and non-diabetic patients from j-Cypher registry.
The American journal of cardiology 20110415
-
Rapamycin impairs proliferation of transplanted islet β cells.
Transplantation 20110415
-
Generation of adaptive regulatory T cells by alloantigen is required for some but not all transplant tolerance protocols.
Transplantation 20110415
-
Ex vivo rapamycin treatment of human cord blood CD34+ cells enhances their engraftment of NSG mice.
Blood cells, molecules & diseases 20110415
-
Th17 cells in alemtuzumab-treated patients: the effect of long-term maintenance immunosuppressive therapy.
Transplantation 20110415
-
Identification and elimination of ion suppression in the quantitative analysis of sirolimus in human blood by LC/ESI-MS/MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110415
-
An accurate quantitative LC/ESI-MS/MS method for sirolimus in human whole blood.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110415
-
Clinical outcome, angiographic outcome, and coronary endothelial function after drug-eluting stent implantation.
Journal of the American College of Cardiology 20110412
-
Unrestricted randomised use of two new generation drug-eluting coronary stents: 2-year patient-related versus stent-related outcomes from the RESOLUTE All Comers trial.
Lancet (London, England) 20110409
-
Long-term safety and efficacy of drug-eluting stents.
Lancet (London, England) 20110409
-
WIPI1 coordinates melanogenic gene transcription and melanosome formation via TORC1 inhibition.
The Journal of biological chemistry 20110408
-
A phase II study of everolimus in combination with imatinib for previously treated advanced renal carcinoma.
Investigational new drugs 20110401
-
Melanoma: from darkness to promise.
American journal of clinical oncology 20110401
-
Complete fracture and migration of a coronary sirolimus-eluting stent.
Journal of cardiovascular medicine (Hagerstown, Md.) 20110401
-
An investigation of reversal of imatinib resistance in the Bcr-Abl positive imatinib-resistant cell line K562r by dasatinib, nilotinib, rapamycin and bortezomib.
International journal of laboratory hematology 20110401
-
The pharmacokinetics of Biolimus A9 after elution from the BioMatrix II stent in patients with coronary artery disease: the Stealth PK Study.
European journal of clinical pharmacology 20110401
-
A high-throughput fluorescence chemical denaturation assay as a general screen for protein-ligand binding.
Analytical biochemistry 20110401
-
Bfl-1/A1 acts as a negative regulator of autophagy in mycobacteria infected macrophages.
The international journal of biochemistry & cell biology 20110401
-
Development and characterization of clinically relevant tumor models from patients with renal cell carcinoma.
European urology 20110401
-
Hot topics in aging research: protein translation and TOR signaling, 2010.
Aging cell 20110401
-
Autophagy regulates myeloid cell differentiation by p62/SQSTM1-mediated degradation of PML-RARα oncoprotein.
Autophagy 20110401
-
Mycophenolate mofetil-based immunosuppression with sirolimus in renal transplantation: a randomized, controlled Spare-the-Nephron trial.
Kidney international 20110401
-
Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
Autophagy 20110401
-
Comparison of haemodialysis patients and non-haemodialysis patients with respect to clinical characteristics and 3-year clinical outcomes after sirolimus-eluting stent implantation: insights from the Japan multi-centre post-marketing surveillance registry.
European heart journal 20110401
-
Late catch-up phenomenon associated with stent fracture after sirolimus-eluting stent implantation: incidence and outcome.
Journal of interventional cardiology 20110401
-
Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin.
Human molecular genetics 20110401
-
Volumetric analysis of MRI data monitoring the treatment of polycystic kidney disease in a mouse model.
Magma (New York, N.Y.) 20110401
-
Zymosan suppresses leukotriene Câ‚„ synthase activity in differentiating monocytes: antagonism by aspirin and protein kinase inhibitors.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110401
-
Oleate-mediated activation of phospholipase D and mammalian target of rapamycin (mTOR) regulates proliferation and rapamycin sensitivity of hepatocarcinoma cells.
Diabetologia 20110401
-
Evaluation of QMS everolimus assay using Hitachi 917 Analyzer: comparison with liquid chromatography/mass spectrometry.
Therapeutic drug monitoring 20110401
-
Targeting of active mTOR inhibits primary leukemia T cells and synergizes with cytotoxic drugs and signaling inhibitors.
Experimental hematology 20110401
-
Secretion of three enzymes for fatty acid synthesis into mouse milk in association with fat globules, and rapid decrease of the secreted enzymes by treatment with rapamycin.
Archives of biochemistry and biophysics 20110401
-
Rapamycin reverses splenomegaly and inhibits tumor development in a transgenic model of Epstein-Barr virus-related Burkitt's lymphoma.
Molecular cancer therapeutics 20110401
-
The Akt-specific inhibitor MK2206 selectively inhibits thyroid cancer cells harboring mutations that can activate the PI3K/Akt pathway.
The Journal of clinical endocrinology and metabolism 20110401
-
Microstructure and drug-release studies of sirolimus-containing poly(lactide-co-glycolide) films.
Journal of biomedical materials research. Part B, Applied biomaterials 20110401
-
Inhibition by rapamycin of the lipoteichoic acid-induced granulocyte-colony stimulating factor expression in mouse macrophages.
Archives of biochemistry and biophysics 20110401
-
The novel Raf inhibitor Raf265 decreases Bcl-2 levels and confers TRAIL-sensitivity to neuroendocrine tumour cells.
Endocrine-related cancer 20110401
-
The identification of raptor as a substrate for p44/42 MAPK.
Endocrinology 20110401
-
Targeting the mTOR kinase domain: the second generation of mTOR inhibitors.
Drug discovery today 20110401
-
Imidazo[1,5-a]pyrazines: orally efficacious inhibitors of mTORC1 and mTORC2.
Bioorganic & medicinal chemistry letters 20110401
-
Novel approaches for preventing or limiting events in diabetic patients (Naples-diabetes) trial: a randomized comparison of 3 drug-eluting stents in diabetic patients.
Circulation. Cardiovascular interventions 20110401
-
Comparison of zotarolimus-eluting stents with sirolimus-eluting and paclitaxel-eluting stents: intimal hyperplasia and vascular changes assessed by volumetric intravascular ultrasound analysis.
Circulation. Cardiovascular interventions 20110401
-
Rapamycin-mediated mTOR inhibition attenuates survivin and sensitizes glioblastoma cells to radiation therapy.
Acta biochimica et biophysica Sinica 20110401
-
Intravascular ultrasound results from the NEVO ResElution-I trial: a randomized, blinded comparison of sirolimus-eluting NEVO stents with paclitaxel-eluting TAXUS Liberté stents in de novo native coronary artery lesions.
Circulation. Cardiovascular interventions 20110401
-
The physiology and pathophysiology of rapamycin resistance: implications for cancer.
Cell cycle (Georgetown, Tex.) 20110401
-
A brief history of TOR.
Biochemical Society transactions 20110401
-
Differing effects of rapamycin and mTOR kinase inhibitors on protein synthesis.
Biochemical Society transactions 20110401
-
Blocking the mTOR pathway: a drug discovery perspective.
Biochemical Society transactions 20110401
-
Benefits of mTOR kinase targeting in oncology: pre-clinical evidence with AZD8055.
Biochemical Society transactions 20110401
-
A critical role for non-coding RNA GAS5 in growth arrest and rapamycin inhibition in human T-lymphocytes.
Biochemical Society transactions 20110401
-
Fragile X mental retardation protein regulates heterosynaptic plasticity in the hippocampus.
Learning & memory (Cold Spring Harbor, N.Y.) 20110401
-
Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: a phase 2 study.
The Lancet. Oncology 20110401
-
New combinations for mantle cell lymphoma: concerted action needed.
The Lancet. Oncology 20110401
-
Paradoxical aspects of rapamycin immunobiology in transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110401
-
Two drug interaction studies of sirolimus in combination with sorafenib or sunitinib in patients with advanced malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 20110401
-
Can the nephron be spared?
Kidney international 20110401
-
[Treatment of metastatic renal cell carcinoma].
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20110401
-
Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy.
The Journal of clinical investigation 20110401
-
Vulnerable plaque inside stent.
JACC. Cardiovascular imaging 20110401
-
Restenosis: delineating the numerous causes of drug-eluting stent restenosis.
Circulation. Cardiovascular interventions 20110401
-
The prognostic utility of the SYNTAX score on 1-year outcomes after revascularization with zotarolimus- and everolimus-eluting stents: a substudy of the RESOLUTE All Comers Trial.
JACC. Cardiovascular interventions 20110401
-
Randomized comparison of a polymer-free sirolimus-eluting stent versus a polymer-based paclitaxel-eluting stent in patients with diabetes mellitus: the LIPSIA Yukon trial.
JACC. Cardiovascular interventions 20110401
-
Five-year outcomes of percutaneous coronary intervention compared to bypass surgery in patients with multivessel disease involving the proximal left anterior descending artery: an ARTS-II sub-study.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110401
-
Comparison between the first and second generation bioresorbable vascular scaffolds: a six month virtual histology study.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110401
-
[Late thrombosis of sirolimus-eluting stent occurring in the perioperative period].
Masui. The Japanese journal of anesthesiology 20110401
-
[Use of mTOR-inhibitors in solid tumors].
Medizinische Monatsschrift fur Pharmazeuten 20110401
-
Comparison of long-term clinical outcome after successful implantation of FIREBIRD and CYPHER sirolimus-eluting stents in daily clinical practice: analysis of a large single-center registry.
Chinese medical journal 20110401
-
Technical difficulty in stenting Supralimus in radial artery graft.
Arquivos brasileiros de cardiologia 20110401
-
[Effect of rapamycin combined with cisplatin on head and neck squamous cancer cells regulated by CCL19].
Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20110401
-
mTOR inhibitors in the treatment of subependymal giant-cell astrocytomas associated with tuberous sclerosis.
Neurosurgery 20110401
-
Ribosomal protein S6 is highly expressed in non-Hodgkin lymphoma and associates with mRNA containing a 5' terminal oligopyrimidine tract.
Oncogene 20110331
-
Targeting the autophagy pathway using ectopic expression of Beclin 1 in combination with rapamycin in drug-resistant v-Ha-ras-transformed NIH 3T3 cells.
Molecules and cells 20110331
-
Stent thrombosis and bleeding complications after implantation of sirolimus-eluting coronary stents in an unselected worldwide population: a report from the e-SELECT (Multi-Center Post-Market Surveillance) registry.
Journal of the American College of Cardiology 20110329
-
Paclitaxel/sirolimus combination coated drug-eluting stent: in vitro and in vivo drug release studies.
Journal of pharmaceutical and biomedical analysis 20110325
-
Drug-eluting or bare-metal stents in large coronary arteries.
The New England journal of medicine 20110324
-
Chromophobe renal cell carcinoma with prolonged response to sequential sunitinib and everolimus.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110320
-
Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation.
The Journal of biological chemistry 20110318
-
Translational medicine: Cancer lessons from mice to humans.
Nature 20110317
-
Long-term (three-year) safety and efficacy of everolimus-eluting stents compared to paclitaxel-eluting stents (from the SPIRIT III Trial).
The American journal of cardiology 20110315
-
Three-year results of safety and efficacy of the everolimus-eluting coronary stent in women (from the SPIRIT III randomized clinical trial).
The American journal of cardiology 20110315
-
MAP kinase-interacting kinase 1 regulates SMAD2-dependent TGF-β signaling pathway in human glioblastoma.
Cancer research 20110315
-
Engineering the ABA plant stress pathway for regulation of induced proximity.
Science signaling 20110315
-
[Rapamycin-mediated interaction of spleen γδT lymphocytes and lung macrophages in acute lung injury of mice induced by lipopolysaccharide].
Zhonghua yi xue za zhi 20110315
-
Sindbis virus replication, is insensitive to rapamycin and torin1, and suppresses Akt/mTOR pathway late during infection in HEK cells.
Biochemical and biophysical research communications 20110311
-
Pancreatic neuroendocrine tumors: role of novel agents. Highlights from the '2011 ASCO Gastrointestinal Cancers Symposium'. San Francisco, CA, USA. January 20-22, 2011.
JOP : Journal of the pancreas 20110309
-
Everolimus-based, calcineurin-inhibitor-free regimen in recipients of de-novo kidney transplants: an open-label, randomised, controlled trial.
Lancet (London, England) 20110305
-
Immunosuppression without calcineurin inhibition: by ZEUS.
Lancet (London, England) 20110305
-
Stent fracture and restenosis after zotarolimus-eluting stent implantation.
International journal of cardiology 20110303
-
Long-term safety and efficacy of sirolimus- vs. paclitaxel-eluting stent implantation for acute ST-elevation myocardial infarction: 3-year follow-up of the PROSIT trial.
International journal of cardiology 20110303
-
Autophagy modification augmented the treatment effects initiated by arsenic trioxide in NB4 cells.
Medical oncology (Northwood, London, England) 20110301
-
Leucine supplementation in rats induced a delay in muscle IR/PI3K signaling pathway associated with overall impaired glucose tolerance.
The Journal of nutritional biochemistry 20110301
-
Comparative assessment of mammalian target of rapamycin inhibitor-eluting stents in the treatment of coronary artery bifurcation lesions: the CASTOR-Bifurcation registry.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110301
-
Hypoxia-inducible factor and mammalian target of rapamycin pathway markers in urothelial carcinoma of the bladder: possible therapeutic implications.
BJU international 20110301
-
Radiologic complete response with sirolimus and sorafenib in a hepatocellular carcinoma patient who relapsed after orthotopic liver transplantation.
Journal of gastrointestinal cancer 20110301
-
Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic β-cells: protective role of p62-positive cytoplasmic inclusions.
Cell death and differentiation 20110301
-
Leukemias induced by altered TRK-signaling are sensitive to mTOR inhibitors in preclinical models.
Annals of hematology 20110301
-
Five-year clinical outcomes of sirolimus-eluting versus paclitaxel-eluting stents in high-risk patients.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110301
-
Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin.
Disease models & mechanisms 20110301
-
Long-term angiographic outcomes of post-sirolimus-eluting stent restenosis in Japanese patients.
Heart and vessels 20110301
-
mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression.
Kidney international 20110301
-
Rapamycin increases the yield and effector function of human γδ T cells stimulated in vitro.
Cancer immunology, immunotherapy : CII 20110301
-
Angiographic late lumen loss at the site of overlap of multiple Cypherâ„¢ sirolimus-eluting stents: ALSOCE study.
Journal of cardiology 20110301
-
Diaphragm rupture in a liver transplant patient under chronic immunosuppressive therapy with sirolimus: rare complication after liver transplantation.
Updates in surgery 20110301
-
Pushing the envelope in the mTOR pathway: the second generation of inhibitors.
Molecular cancer therapeutics 20110301
-
Heat stress enhances mTOR signaling after resistance exercise in human skeletal muscle.
The journal of physiological sciences : JPS 20110301
-
The double-faced metabolic and inflammatory effects of standard drug therapy in patients after percutaneous treatment with drug-eluting stent.
Atherosclerosis 20110301
-
mTOR inhibitors show promising in vitro activity in bladder cancer and head and neck squamous cell carcinoma.
Oncology reports 20110301
-
mTOR couples cellular nutrient sensing to organismal metabolic homeostasis.
Trends in endocrinology and metabolism: TEM 20110301
-
Regulatory T cells require mammalian target of rapamycin signaling to maintain both homeostasis and alloantigen-driven proliferation in lymphocyte-replete mice.
Journal of immunology (Baltimore, Md. : 1950) 20110301
-
Current and future directions in mammalian target of rapamycin inhibitors development.
Expert opinion on investigational drugs 20110301
-
Biolimus-eluting biodegradable polymer-coated stent versus bare metal stent in acute ST-elevation and non-ST elevation myocardial infarction: Justification for biodegradable polymer-coated stent in acute coronary syndrome (JANICE) registry.
Acute cardiac care 20110301
-
Cyclosporin A, but not everolimus, inhibits DNA repair mediated by calcineurin: implications for tumorigenesis under immunosuppression.
Experimental dermatology 20110301
-
The outcome of bifurcation lesion stenting using a biolimus-eluting stent with a bio-degradable polymer compared to a sirolimus-eluting stent with a durable polymer.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110301
-
Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation.
The Journal of clinical investigation 20110301
-
Analytical and pharmacological aspects of therapeutic drug monitoring of mTOR inhibitors.
Current drug metabolism 20110301
-
Sirolimus enhances the magnitude and quality of viral-specific CD8+ T-cell responses to vaccinia virus vaccination in rhesus macaques.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110301
-
Weekly bortezomib in combination with temsirolimus in relapsed or relapsed and refractory multiple myeloma: a multicentre, phase 1/2, open-label, dose-escalation study.
The Lancet. Oncology 20110301
-
If I've heard it once, I've heard it (not yet) a hundred times.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110301
-
Primary percutaneous coronary intervention of an unprotected left main using mini-crush drug-eluting stents facilitated by intracoronary reteplase.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110301
-
Noninfectious pneumonitis in a patient with renal cell carcinoma treated with everolimus.
Oncology nursing forum 20110301
-
Reduced VEGF production, angiogenesis, and vascular regrowth contribute to the antitumor properties of dual mTORC1/mTORC2 inhibitors.
Cancer research 20110301
-
Ruptured-plaque-like appearance of restenotic tissue following sirolimus-eluting stent implantation: an optical coherence tomography case study.
The Journal of invasive cardiology 20110301
-
CYP3A5 genotype does not influence everolimus in vitro metabolism and clinical pharmacokinetics in renal transplant recipients.
Transplantation 20110301
-
Potential of mTOR inhibitors for the treatment of subependymal giant cell astrocytomas in tuberous sclerosis complex.
Aging 20110301
-
A randomized comparison of sirolimus- versus paclitaxel-eluting stent implantation in patients with diabetes mellitus: 4-year clinical outcomes of DES-DIABETES (drug-eluting stent in patients with DIABETES mellitus) trial.
JACC. Cardiovascular interventions 20110301
-
Prospective randomized comparison of sirolimus- or everolimus-eluting stent to treat bifurcated lesions by provisional approach.
JACC. Cardiovascular interventions 20110301
-
Steroid and calcineurin inhibitor-sparing protocols in kidney transplantation.
Transplantation proceedings 20110301
-
Conversion to low-dose tacrolimus or rapamycin 3 months after kidney transplantation: a prospective, protocol biopsy-guided study.
Transplantation proceedings 20110301
-
Rapamycin prevents interstitial fibrosis in renal allografts through decreasing angiogenesis and inflammation.
Transplantation proceedings 20110301
-
Exploring long-term protection of normal human fibroblasts and epithelial cells from chemotherapy in cell culture.
Oncotarget 20110301
-
Future directions of mammalian target of rapamycin (mTOR) inhibitor therapy in renal cell carcinoma.
Targeted oncology 20110301
-
Spatial distribution of neo-intimal hyperplasia 6 months after zotarolimus-eluting stent implantation, analysed by optical coherence tomography.
Archives of cardiovascular diseases 20110301
-
Mammalian target of rapamycin as a target in hematological malignancies.
Targeted oncology 20110301
-
A prospective multicenter parallel-controlled trial of TIVOLI biodegradable-polymer-based sirolimus-eluting stent compared to ENDEAVOR zotarolimus-eluting stent for the treatment of coronary artery disease: 8-month angiographic and 2-year clinical follow-up results.
Chinese medical journal 20110301
-
Efficacy and safety of Firebird sirolimus-eluting stent in treatment of complex coronary lesions in Chinese patients: one-year clinical and eight-month angiographic outcomes from the FIREMAN registry.
Chinese medical journal 20110301
-
Six-month clinical outcomes of Firebird 2TM sirolimus-eluting stent implantation in real-world patients with coronary artery diseases.
Chinese medical journal 20110301
-
Long-term effects of biodegradable versus durable polymer-coated sirolimus-eluting stents on coronary arterial wall morphology assessed by virtual histology intravascular ultrasound.
Chinese medical journal 20110301
-
Targeting the target of rapamycin (TOR): looking to mother nature.
Targeted oncology 20110301
-
The emerging role of mammalian target of rapamycin inhibitors in the treatment of sarcomas.
Targeted oncology 20110301
-
[Effect of daunorubicin and rapamycin combination on the proliferation of acute leukemia cells].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110301
-
Mechanisms of mTOR inhibitor resistance in cancer therapy.
Targeted oncology 20110301
-
[Current status in molecular-targeted therapy and IFNα for renal cell carcinoma in Japan].
Hinyokika kiyo. Acta urologica Japonica 20110301
-
[Determination of the content of zotarolimus on the drug eluting stents by HPLC].
Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation 20110301
-
Resveratrol enhances the anti-tumor activity of the mTOR inhibitor rapamycin in multiple breast cancer cell lines mainly by suppressing rapamycin-induced AKT signaling.
Cancer letters 20110227
-
Embryonic pig pancreatic tissue for the treatment of diabetes: potential role of immune suppression with 'off-the-shelf' third-party regulatory T cells.
Transplantation 20110227
-
Inhibitory effects of the HDAC inhibitor valproic acid on prostate cancer growth are enhanced by simultaneous application of the mTOR inhibitor RAD001.
Life sciences 20110227
-
mTOR-dependent regulation of PHLPP expression controls the rapamycin sensitivity in cancer cells.
The Journal of biological chemistry 20110225
-
A randomized clinical study comparing double kissing crush with provisional stenting for treatment of coronary bifurcation lesions: results from the DKCRUSH-II (Double Kissing Crush versus Provisional Stenting Technique for Treatment of Coronary Bifurcation Lesions) trial.
Journal of the American College of Cardiology 20110222
-
mTOR inhibitor treatment of pancreatic cancer in a patient With Peutz-Jeghers syndrome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110220
-
Use of drug-eluting stents for chronic total occlusions: a systematic review and meta-analysis.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110215
-
FOXO3a reactivation mediates the synergistic cytotoxic effects of rapamycin and cisplatin in oral squamous cell carcinoma cells.
Toxicology and applied pharmacology 20110215
-
Combination mTOR and IGF-1R inhibition: phase I trial of everolimus and figitumumab in patients with advanced sarcomas and other solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 20110215
-
Two-year safety and effectiveness of sirolimus-eluting stents (from a prospective registry).
The American journal of cardiology 20110215
-
Temsirolimus, an mTOR inhibitor, enhances anti-tumour effects of heat shock protein cancer vaccines.
British journal of cancer 20110215
-
Calcineurin inhibitor-free monotherapy in human leukocyte antigen–identical live donor renal transplantation.
Transplantation 20110215
-
Perivascular sirolimus-delivery system.
International journal of pharmaceutics 20110214
-
Everolimus for advanced pancreatic neuroendocrine tumors.
The New England journal of medicine 20110210
-
Promising advances in the treatment of malignant pancreatic endocrine tumors.
The New England journal of medicine 20110210
-
Everolimus and giant-cell astrocytomas in tuberous sclerosis.
The New England journal of medicine 20110210
-
Everolimus and giant-cell astrocytomas in tuberous sclerosis.
The New England journal of medicine 20110210
-
Spinal phosphinositide 3-kinase-Akt-mammalian target of rapamycin signaling cascades in inflammation-induced hyperalgesia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20110209
-
Rapamycin suppresses mossy fiber sprouting but not seizure frequency in a mouse model of temporal lobe epilepsy.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20110209
-
Sirolimus eluting stent restenosis: impact of angiographic patterns and the treatment factors on angiographic outcomes in contemporary practice.
International journal of cardiology 20110203
-
Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20110202
-
Early graft dysfunction in a child with renal transplantation.
Pediatric nephrology (Berlin, Germany) 20110201
-
mTOR partly mediates insulin resistance by phosphorylation of insulin receptor substrate-1 on serine(307) residues after burn.
Burns : journal of the International Society for Burn Injuries 20110201
-
Integrating bevacizumab, everolimus, and lapatinib into current neoadjuvant chemotherapy regimen for primary breast cancer. Safety results of the GeparQuinto trial.
Annals of oncology : official journal of the European Society for Medical Oncology 20110201
-
The PI3K/Akt/mTOR pathway is activated in murine lupus nephritis and downregulated by rapamycin.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110201
-
Comparison of sirolimus with azathioprine in a tacrolimus-based immunosuppressive regimen in lung transplantation.
American journal of respiratory and critical care medicine 20110201
-
National Cancer Institute pediatric preclinical testing program: model description for in vitro cytotoxicity testing.
Pediatric blood & cancer 20110201
-
Increased risk of venous thromboembolism with a sirolimus-based immunosuppression regimen in lung transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20110201
-
Aging and TOR: interwoven in the fabric of life.
Cellular and molecular life sciences : CMLS 20110201
-
Comparison of blood sirolimus, tacrolimus and everolimus concentrations measured by LC-MS/MS, HPLC-UV and immunoassay methods.
Clinical biochemistry 20110201
-
Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice.
The journals of gerontology. Series A, Biological sciences and medical sciences 20110201
-
Beta cell function during rapamycin monotherapy in long-term type 1 diabetes.
Diabetologia 20110201
-
Vertical inhibition of the mTORC1/mTORC2/PI3K pathway shows synergistic effects against melanoma in vitro and in vivo.
The Journal of investigative dermatology 20110201
-
Antagonistic interactions between the cAMP-dependent protein kinase and Tor signaling pathways modulate cell growth in Saccharomyces cerevisiae.
Genetics 20110201
-
A phase I study of bevacizumab (B) in combination with everolimus (E) and erlotinib (E) in advanced cancer (BEE).
Cancer chemotherapy and pharmacology 20110201
-
Evidence for the involvement of mTOR inhibition and basal autophagy in familial Mediterranean fever phenotype.
Human immunology 20110201
-
Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition.
Autophagy 20110201
-
Dissecting the dynamic turnover of GFP-LC3 in the autolysosome.
Autophagy 20110201
-
mTOR inhibitors and sorafenib for recurrent heptocellular carcinoma after orthotopic liver transplantation.
Journal of hepatology 20110201
-
Rapamycin for treating Tuberous sclerosis and Autism spectrum disorders.
Trends in molecular medicine 20110201
-
Combined targeting of the VEGFr/EGFr and the mammalian target of rapamycin (mTOR) signaling pathway delays cell cycle progression and alters adhesion behavior of prostate carcinoma cells.
Cancer letters 20110201
-
A comparative assessment by optical coherence tomography of the performance of the first and second generation of the everolimus-eluting bioresorbable vascular scaffolds.
European heart journal 20110201
-
Autophagy aids membrane expansion by neuropathic Schwann cells.
Autophagy 20110201
-
A phase II trial of the oral mTOR inhibitor everolimus in relapsed aggressive lymphoma.
Leukemia 20110201
-
Clinical safety and efficacy of everolimus-eluting stents compared to paclitaxel-eluting stents in patients with coronary artery disease.
Annals of medicine 20110201
-
Loss of canonical insulin signaling accelerates vascular smooth muscle cell proliferation and migration through changes in p27Kip1 regulation.
Endocrinology 20110201
-
Systemic influence of immunosuppressive drugs on small and large bowel transport and barrier function.
Transplant international : official journal of the European Society for Organ Transplantation 20110201
-
Interpreting mammalian target of rapamycin and cell growth inhibition in a genetically engineered mouse model of Nf1-deficient astrocytes.
Molecular cancer therapeutics 20110201
-
Influence of age on the clinical outcomes of coronary revascularisation for the treatment of patients with multivessel de novo coronary artery lesions: sirolimus-eluting stent vs. coronary artery bypass surgery and bare metal stent, insight from the multicentre randomised Arterial Revascularisation Therapy Study Part I (ARTS-I) and Part II (ARTS-II).
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110201
-
Infected coronary artery pseudoaneurysm after repeated percutaneous coronary intervention.
The Annals of thoracic surgery 20110201
-
Protein synthesis in plasma cells is regulated by crosstalk between endoplasmic reticulum stress and mTOR signaling.
European journal of immunology 20110201
-
The mTOR inhibitor rapamycin suppresses DNA double-strand break repair.
Radiation research 20110201
-
Randomized comparison of percutaneous coronary intervention with sirolimus-eluting stents versus coronary artery bypass grafting in unprotected left main stem stenosis.
Journal of the American College of Cardiology 20110201
-
Total recall of radiotherapy with mTOR inhibitors: a novel and potentially frequent side-effect?
Annals of oncology : official journal of the European Society for Medical Oncology 20110201
-
Very late thrombosis of sirolimus-eluting stent despite dual antiplatelet therapy for 4 years in a patient with lung cancer.
Minerva cardioangiologica 20110201
-
Tailoring immunosuppressive therapy for lung transplantation: moving beyond hand-me-down data.
American journal of respiratory and critical care medicine 20110201
-
Procedural and clinical evaluation of the novel zotarolimus-eluting resolute stent in patients with unselected bifurcated coronary stenosis treated by provisional approach: a multicenter registry.
The Journal of invasive cardiology 20110201
-
Resoluteâ„¢ drug-eluting stent: a resolution for bifurcation lesions?
The Journal of invasive cardiology 20110201
-
Primary everolimus-eluting stenting versus balloon angioplasty with bailout bare metal stenting of long infrapopliteal lesions for treatment of critical limb ischemia.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20110201
-
Targeted therapies for the treatment of metastatic renal cell carcinoma: clinical evidence.
The oncologist 20110201
-
Beyond traditional outcomes: improving quality of life in patients with renal cell carcinoma.
The oncologist 20110201
-
Treatment-associated adverse event management in the advanced renal cell carcinoma patient treated with targeted therapies.
The oncologist 20110201
-
Effectiveness of paclitaxel-eluting balloon catheter in patients with sirolimus-eluting stent restenosis.
JACC. Cardiovascular interventions 20110201
-
The SPIRIT V study: a clinical evaluation of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with de novo coronary artery lesions.
JACC. Cardiovascular interventions 20110201
-
Signaling to the ribosome in cancer--It is more than just mTORC1.
IUBMB life 20110201
-
[Types and characteristic features of drug-eluting stents].
Nihon rinsho. Japanese journal of clinical medicine 20110201
-
Ten-month laryngeal allograft survival with use of pulsed everolimus and anti-alphabeta T-cell receptor antibody immunosuppression.
The Annals of otology, rhinology, and laryngology 20110201
-
Conversion from cyclosporine to sirolimus in chronic renal allograft dysfunction: a 4-year prospective study.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20110201
-
Immunosuppressive therapy in children.
Journal of the Indian Medical Association 20110201
-
Rapamycin treatment causes developmental delay, pigmentation defects, and gastrointestinal malformation on Xenopus embryogenesis.
Biochemical and biophysical research communications 20110128
-
Allospecific regulatory effects of sirolimus and tacrolimus in the human mixed lymphocyte reaction.
Transplantation 20110127
-
Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP.
Journal of the American Chemical Society 20110126
-
Coronary responses and differential mechanisms of late stent thrombosis attributed to first-generation sirolimus- and paclitaxel-eluting stents.
Journal of the American College of Cardiology 20110125
-
Sirolimus- versus paclitaxel-eluting stents in patients with acute myocardial infarction: a meta-analysis of randomized trials.
International journal of cardiology 20110121
-
Randomized study on provisional stenting with sirolimus-eluting stent vs. bare metal stent for the treatment of true coronary bifurcations: the PROSUMER (PROvisional with sirolimus-eluting vs. bare metal stents in truE bifuRcations) study.
International journal of cardiology 20110121
-
Translation of 5' terminal oligopyrimidine tract (5'TOP) mRNAs in Aplysia Californica is regulated by the target of rapamycin (TOR).
Biochemical and biophysical research communications 20110121
-
mTOR inhibitors and autosomal dominant polycystic kidney disease.
The New England journal of medicine 20110120
-
mTOR inhibitors and autosomal dominant polycystic kidney disease.
The New England journal of medicine 20110120
-
mTOR inhibitors and autosomal dominant polycystic kidney disease.
The New England journal of medicine 20110120
-
Protective effect of immunosuppressive treatment before orthotopic kidney autotransplantation.
Transplant immunology 20110115
-
Adoptive transfer of DNT cells induces long-term cardiac allograft survival and augments recipient CD4(+)Foxp3(+) Treg cell accumulation.
Transplant immunology 20110115
-
Haplotypic arrangement in CYP3A locus is associated with side effects of proliferative signal inhibitors in renal transplant recipients.
Transplantation 20110115
-
Mean glomerular volume after renal transplantation in patients receiving sirolimus and cyclosporine a compared with elimination of cyclosporine a at 3 months.
Transplantation 20110115
-
Switching to sirolimus-based immune suppression after liver transplantation is safe and effective: a single-center experience.
Transplantation 20110115
-
Multi-timescale dynamics study of FKBP12 along the rapamycin-mTOR binding coordinate.
Journal of molecular biology 20110114
-
Inhibition of the mammalian target of rapamycin pathway by rapamycin blocks cocaine-induced locomotor sensitization.
Neuroscience 20110113
-
Pipecolic acid derivatives as small-molecule inhibitors of the Legionella MIP protein.
Journal of medicinal chemistry 20110113
-
A photocleavable rapamycin conjugate for spatiotemporal control of small GTPase activity.
Journal of the American Chemical Society 20110112
-
Identification of FUSE-binding protein 1 as a regulatory mRNA-binding protein that represses nucleophosmin translation.
Oncogene 20110106
-
α-TEA cooperates with MEK or mTOR inhibitors to induce apoptosis via targeting IRS/PI3K pathways.
British journal of cancer 20110104
-
mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice.
The Journal of clinical investigation 20110104
-
Coronary angiography and computed tomography angiography in the diagnosis of extrinsic compression of left internal mammary artery.
Journal of cardiovascular medicine (Hagerstown, Md.) 20110101
-
The role of CYP3A5 genotypes in dose requirements of tacrolimus and everolimus after heart transplantation.
Clinical transplantation 20110101
-
Inhibitors of phosphatidylinositol 3-kinase and mTOR but not Akt enhance replication of bovine ephemeral fever virus.
Veterinary journal (London, England : 1997) 20110101
-
Randomized, double-blind, placebo-controlled, single intravenous dose-escalation study to evaluate the safety, tolerability, and pharmacokinetics of the novel coronary smooth muscle cell proliferation inhibitor Biolimus A9 in healthy individuals.
Journal of clinical pharmacology 20110101
-
Inhibition of bladder tumour growth by sirolimus in an experimental carcinogenesis model.
BJU international 20110101
-
Impressive response to temsirolimus in a patient with chemotherapy refractory diffuse large B-cell non-Hodgkin's lymphoma.
Annals of hematology 20110101
-
Steroid minimization for sirolimus-treated renal transplant recipients.
Clinical transplantation 20110101
-
First nine-month complete invasive assessment (angiography, IVUS, and OCT) of the novel NEVO sirolimus-eluting stent with biodegradable polymer.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101
-
Sirolimus versus paclitaxel coronary stents in clinical practice.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101
-
Everolimus and PTK/ZK show synergistic growth inhibition in the orthotopic BL16/BL6 murine melanoma model.
Cancer chemotherapy and pharmacology 20110101
-
Temsirolimus in VEGF-refractory metastatic renal cell carcinoma.
Annals of oncology : official journal of the European Society for Medical Oncology 20110101
-
Inhibition of mTOR with sirolimus does not attenuate progression of liver and kidney disease in PCK rats.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110101
-
Calcineurin inhibitor sparing regimens using m-target of rapamycin inhibitors: an opportunity to improve cardiovascular risk following kidney transplantation?
Transplant international : official journal of the European Society for Organ Transplantation 20110101
-
Regression of subependymal giant cell astrocytomas with RAD001 (Everolimus) in tuberous sclerosis complex.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20110101
-
Activation of mTOR and RhoA is a major mechanism by which Ceramide 1-phosphate stimulates macrophage proliferation.
Cellular signalling 20110101
-
Mammalian target of rapamycin (mTOR) phosphorylates inositol 1,4,5-trisphosphate receptor type 2 and increases its Ca(2+) release activity.
Cellular signalling 20110101
-
Select nutrients in the ovine uterine lumen. VII. Effects of arginine, leucine, glutamine, and glucose on trophectoderm cell signaling, proliferation, and migration.
Biology of reproduction 20110101
-
Differential modulation of the cytokine-induced MMP-9/TIMP-1 protease-antiprotease system by the mTOR inhibitor rapamycin.
Biochemical pharmacology 20110101
-
Vitamin K3 attenuates cerulein-induced acute pancreatitis through inhibition of the autophagic pathway.
Pancreas 20110101
-
Evaluation of the mTOR inhibitor, everolimus, in combination with cytotoxic antitumor agents using human tumor models in vitro and in vivo.
Anti-cancer drugs 20110101
-
Angiographic and intravascular ultrasound follow up of paclitaxel- and sirolimus-eluting stent after poststent high-pressure balloon dilation: from the poststent optimal stent expansion trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101
-
Oral sirolimus after bare metal stent implantation: a glimpse to the future.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101
-
Activation of STAT1 is required for interferon-alpha-mediated cell death.
Experimental cell research 20110101
-
mTORC1/2 and rapamycin in female Han:SPRD rats with polycystic kidney disease.
American journal of physiology. Renal physiology 20110101
-
Enhanced sensitivity to rapamycin following long-term oestrogen deprivation in MCF-7, T-47-D and ZR-75-1 human breast cancer cells.
The Journal of endocrinology 20110101
-
The mammalian target of rapamycin inhibitor RAD001 (everolimus) synergizes with chemotherapeutic agents, ionizing radiation and proteasome inhibitors in pre-B acute lymphocytic leukemia.
Haematologica 20110101
-
Sirolimus damages podocytes in rats with protein overload nephropathy.
Journal of nephrology 20110101
-
Phase III trial of everolimus in metastatic renal cell carcinoma: subgroup analysis of Japanese patients from RECORD-1.
Japanese journal of clinical oncology 20110101
-
Identification of clinically used drugs that activate pregnane X receptors.
Drug metabolism and disposition: the biological fate of chemicals 20110101
-
Long-term outcome of sirolimus-eluting stent implantation for left main coronary artery stenosis in infancy.
Pediatric cardiology 20110101
-
Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase.
Autophagy 20110101
-
Deciphering the signaling pathways of cancer stem cells of glioblastoma multiforme: role of Akt/mTOR and MAPK pathways.
Advances in enzyme regulation 20110101
-
Partial graft recovery following eradication of hepatitis E virus infection after successful islet allograft transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20110101
-
Assessment by optical coherence tomography of stent struts across side branch. -Comparison of bare-metal stents and drug-elution stents.-.
Circulation journal : official journal of the Japanese Circulation Society 20110101
-
Age and sex differences in the effects of the immunosuppressants cyclosporine, sirolimus and everolimus on rat brain metabolism.
Neurotoxicology 20110101
-
Albuminuria after renal transplantation: maintenance with sirolimus/low-dose tacrolimus vs. mycophenolate mofetil/high-dose tacrolimus.
Clinical transplantation 20110101
-
Drug-eluting stents for the treatment of pulmonary vein stenosis after atrial fibrillation ablation.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110101
-
Impact of cytochrome P450 2C19*2 polymorphism on intra-stent thrombus after drug-eluting stent implantation in Japanese patients receiving clopidogrel.
Circulation journal : official journal of the Japanese Circulation Society 20110101
-
Predictors of stent fracture in patients treated with closed-cell design stents: sirolimus-eluting stent and its bare-metal counterpart, the BX velocity stent.
Coronary artery disease 20110101
-
Phase I trial of oral mTOR inhibitor everolimus in combination with trastuzumab and vinorelbine in pre-treated patients with HER2-overexpressing metastatic breast cancer.
Breast cancer research and treatment 20110101
-
Rapamycin inhibits lipopolysaccharide induction of granulocyte-colony stimulating factor and inducible nitric oxide synthase expression in macrophages by reducing the levels of octamer-binding factor-2.
The FEBS journal 20110101
-
Immunosuppression with belatacept-based, corticosteroid-avoiding regimens in de novo kidney transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110101
-
The relationship between late lumen loss and restenosis among various drug-eluting stents: a systematic review and meta-regression analysis of randomized clinical trials.
Atherosclerosis 20110101
-
Mechanisms mediating the cardioprotective effects of rapamycin in ischaemia-reperfusion injury.
Clinical and experimental pharmacology & physiology 20110101
-
Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway.
The FEBS journal 20110101
-
AP-1 regulates cyclin D1 and c-MYC transcription in an AKT-dependent manner in response to mTOR inhibition: role of AIP4/Itch-mediated JUNB degradation.
Molecular cancer research : MCR 20110101
-
Evaluation of the novel protein kinase C inhibitor sotrastaurin as immunosuppressive therapy after renal transplantation.
Expert opinion on drug metabolism & toxicology 20110101
-
Retrospective comparison of clinical and angiographic outcomes after primary stenting using sirolimus-eluting and bare-metal stents in nonrandomized consecutive 568 patients with first ST-segment elevated myocardial infarctions.
Journal of cardiology 20110101
-
Tolerability of everolimus-based immunosuppression in maintenance liver transplant recipients.
Clinical transplantation 20110101
-
Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology.
European journal of heart failure 20110101
-
Control of carcinoid syndrome with everolimus.
Annals of oncology : official journal of the European Society for Medical Oncology 20110101
-
Clinical and angiographic outcomes with sirolimus-eluting stent for coronary bifurcation lesions. The J-PMS study.
Circulation journal : official journal of the Japanese Circulation Society 20110101
-
Drug-eluting stents vs. bare metal stents in saphenous vein graft disease. Insights from a meta-analysis of 7,090 patients.
Circulation journal : official journal of the Japanese Circulation Society 20110101
-
Neointimal coverage over coronary stent struts crossing the side branch Ostia.
Circulation journal : official journal of the Japanese Circulation Society 20110101
-
Prolonged survival in renal transplant recipient with advanced renal cell carcinoma by everolimus and sorafenib.
Nephrology (Carlton, Vic.) 20110101
-
Everolimus: a new mammalian target of rapamycin inhibitor for the treatment of advanced renal cell carcinoma.
The Annals of pharmacotherapy 20110101
-
Sirolimus- versus paclitaxel-eluting stents for unselected patients with coronary artery disease.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101
-
Nevo stent: a successful stent makeover.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101
-
Tuberous sclerosis complex: tumors and tumorigenesis.
International journal of dermatology 20110101
-
Protein kinase B/Akt regulation in diabetic kidney disease.
Frontiers in bioscience (Scholar edition) 20110101
-
Drug interaction between rifampicin and sirolimus in transplant patients.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20110101
-
Medical management of skin disease: recent advances and future directions.
Journal of drugs in dermatology : JDD 20110101
-
Sirolimus-eluting stent implantation versus beta-irradiation for the treatment of in-stent restenotic lesions: clinical and ultrasound results from a randomised trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110101
-
Drug eluting stents for the treatment of bare metal in-stent restenosis: long-term outcomes in real world practice.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110101
-
Clinical usefulness of drug-eluting stents in the treatment of dialysis patients with coronary artery disease.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110101
-
The mTOR kinase inhibitor rapamycin decreases iNOS mRNA stability in astrocytes.
Journal of neuroinflammation 20110101
-
Clinical characteristics of coronary drug-eluting stent fracture: insights from a two-center des registry.
Journal of Korean medical science 20110101
-
Therapeutic targeting the loss of the birt-hogg-dube suppressor gene.
Molecular cancer therapeutics 20110101
-
Targeting the PI3K/mTOR pathway in murine endocrine cell lines: in vitro and in vivo effects on tumor cell growth.
The American journal of pathology 20110101
-
Conditional depletion of nuclear proteins by the Anchor Away system.
Current protocols in molecular biology 20110101
-
The final answer? For the treatment of saphenous vein graft disease, drug-eluting stents vs. bare-metal stents.
Circulation journal : official journal of the Japanese Circulation Society 20110101
-
Two-dose-level confirmatory study of the pharmacokinetics and tolerability of everolimus in Chinese patients with advanced solid tumors.
Journal of hematology & oncology 20110101
-
Two-year outcome of Turkish patients treated with Zotarolimus versus Paclitaxel eluting stents in an unselected population with coronary artery disease in the real world: a prospective non-randomized registry in southern Turkey.
International journal of medical sciences 20110101
-
Selective inhibition of cyclooxygenase-2 suppresses metastatic disease without affecting primary tumor growth in a murine model of Ewing sarcoma.
Journal of pediatric surgery 20110101
-
Good outcomes with cyclosporine very low exposure with everolimus high exposure in renal transplant patients.
Journal of nephrology 20110101
-
Late stent thrombosis secondary to carbon monoxide poisoning.
Cardiovascular revascularization medicine : including molecular interventions 20110101
-
Everolimus resolving hypoglycemia, producing hyperglycemia, and necessitating insulin use in a patient with diabetes and nonresectable malignant insulinoma.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20110101
-
Four-year follow-up of TYPHOON (trial to assess the use of the CYPHer sirolimus-eluting coronary stent in acute myocardial infarction treated with BallOON angioplasty).
JACC. Cardiovascular interventions 20110101
-
Very late stent thrombosis after primary percutaneous coronary intervention with bare-metal and drug-eluting stents for ST-segment elevation myocardial infarction: a 15-year single-center experience.
JACC. Cardiovascular interventions 20110101
-
Long-term follow-up of drug-eluting stents placed in the setting of ST-segment elevation myocardial infarction.
JACC. Cardiovascular interventions 20110101
-
Persistent coronary no flow after wire insertion is an early and readily available mortality risk factor despite successful mechanical intervention in acute myocardial infarction: a pooled analysis from the STRATEGY (Single High-Dose Bolus Tirofiban and Sirolimus-Eluting Stent Versus Abciximab and Bare-Metal Stent in Acute Myocardial Infarction) and MULTISTRATEGY (Multicenter Evaluation of Single High-Dose Bolus Tirofiban Versus Abciximab With Sirolimus-Eluting Stent or Bare-Metal Stent in Acute Myocardial
JACC. Cardiovascular interventions 20110101
-
Prediction of 1-year clinical outcomes using the SYNTAX score in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a substudy of the STRATEGY (Single High-Dose Bolus Tirofiban and Sirolimus-Eluting Stent Versus Abciximab and Bare-Metal Stent in Acute Myocardial Infarction) and MULTISTRATEGY (Multicenter Evaluation of Single High-Dose Bolus Tirofiban Versus Abciximab With Sirolimus-Eluting Stent or Bare-Metal Stent in Acute Myocardial Infarc
JACC. Cardiovascular interventions 20110101
-
Late restenosis following sirolimus-eluting stent implantation.
JACC. Cardiovascular interventions 20110101
-
Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells.
PloS one 20110101
-
The impact of sirolimus on hepatitis C recurrence after liver transplantation.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20110101
-
Rapamycin blocks production of KSHV/HHV8: insights into the anti-tumor activity of an immunosuppressant drug.
PloS one 20110101
-
Initial experience with temsirolimus in 2nd-, 3rd- and 4th-line therapy for metastatic renal cell cancer: good clinical response.
Urologia internationalis 20110101
-
Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma.
PloS one 20110101
-
Clinical evidence on the use of anti-mTOR drugs in renal transplantation.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101
-
Temsirolimus in metastatic chromophobe renal cell carcinoma after interferon and sorafenib therapy.
Anticancer research 20110101
-
Response to mTOR inhibition: activity of eIF4E predicts sensitivity in cell lines and acquired changes in eIF4E regulation in breast cancer.
Molecular cancer 20110101
-
The incidence of cancer and potential role of sirolimus immunosuppression conversion on mortality among a single-center renal transplantation cohort of 1,816 patients.
Transplantation proceedings 20110101
-
Sirolimus prevents short-term renal changes induced by ischemia-reperfusion injury in rats.
American journal of nephrology 20110101
-
Retrospective analyses of patient characteristics having predictive impact on survival under everolimus.
Onkologie 20110101
-
Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer.
Breast cancer research : BCR 20110101
-
The clinical evaluation of the Endeavor zotarolimus-eluting coronary stent in Japanese patients with de novo native coronary artery lesions: primary results and 3-year follow-up of the Endeavor Japan study.
Cardiovascular revascularization medicine : including molecular interventions 20110101
-
Late regression of Cypher in-stent restenosis.
Cardiovascular revascularization medicine : including molecular interventions 20110101
-
[Immunosuppressive agents in kidney transplantation].
Nihon Jinzo Gakkai shi 20110101
-
[Autosomal dominant polycystic kidney disease].
Nihon Jinzo Gakkai shi 20110101
-
Efficacy of paclitaxel-eluting stent in patients with impaired glucose tolerance--comparison with sirolimus-eluting stent.
Circulation journal : official journal of the Japanese Circulation Society 20110101
-
Candesartan with pioglitazone protects against endothelial dysfunction and inflammatory responses in porcine coronary arteries implanted with sirolimus-eluting stents.
Circulation journal : official journal of the Japanese Circulation Society 20110101
-
Angioscopic assessment of arterial repair following biodegradable polymer-coated biolimus A9-eluting stent implantation. - Comparison with durable polymer-coated sirolimus-eluting stent-.
Circulation journal : official journal of the Japanese Circulation Society 20110101
-
Rapamycin potentiates cytotoxicity by docetaxel possibly through downregulation of Survivin in lung cancer cells.
Journal of experimental & clinical cancer research : CR 20110101
-
Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis.
Nature communications 20110101
-
Inverse probability weighting to control for censoring in a post hoc analysis of quality-adjusted survival data from a clinical trial of temsirolimus for renal cell carcinoma.
Journal of medical economics 20110101
-
Conversion from sirolimus to everolimus in kidney transplant recipients receiving a calcineurin-free regimen.
Clinical transplantation 20110101
-
Targeting FK506 binding proteins to fight malarial and bacterial infections: current advances and future perspectives.
Current medicinal chemistry 20110101
-
Combined therapeutic strategy to improve vascular endothelial function after implantation of sirolimus-eluting stents.
Circulation journal : official journal of the Japanese Circulation Society 20110101
-
Protective role of autophagy in AGE-induced early injury of human vascular endothelial cells.
Molecular medicine reports 20110101
-
Regression of Kaposi's sarcoma in a Sudanese kidney transplant recipient after conversion to sirolimus: a focus on a common clinical problem.
Arab journal of nephrology and transplantation 20110101
-
The impact of new generation drug-eluting stent implantation on patients with chronic kidney disease and a single lesion in the proximal segment of the left anterior descending artery.
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20110101
-
Tuberous sclerosis complex-1 deficiency attenuates diet-induced hepatic lipid accumulation.
PloS one 20110101
-
Retrospective comparison of clinical and angiographic outcomes after sirolimus-eluting and bare-metal stent implantation in 312 consecutive, nonrandomized severely calcified lesions using a rotablator.
International heart journal 20110101
-
Switching to sirolimus monotherapy for de novo tumors after liver transplantation. A preliminary experience.
Hepato-gastroenterology 20110101
-
Amino acid signaling in TOR activation.
Annual review of biochemistry 20110101
-
Host-based Th2 cell therapy for prolongation of cardiac allograft viability.
PloS one 20110101
-
Rapid estimation of whole blood everolimus concentrations using architect sirolimus immunoassay and mathematical equations: comparison with everolimus values determined by liquid chromatography/mass spectrometry.
Journal of clinical laboratory analysis 20110101
-
Rapamycin-loaded nanoparticles for inhibition of neointimal hyperplasia in experimental vein grafts.
Journal of cardiothoracic surgery 20110101
-
Antigen-independent IFN-γ production by human naïve CD4 T cells activated by IL-12 plus IL-18.
PloS one 20110101
-
Rapamycin-induced impaired wound healing is associated with compromised tissue lactate accumulation and extracellular matrix remodeling.
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20110101
-
Sex difference in long-term clinical outcome after sirolimus-eluting stent implantation.
Coronary artery disease 20110101
-
[Breast cancer therapy with combination of endocrine and target drugs].
Voprosy onkologii 20110101
-
Is sirolimus a therapeutic option for patients with progressive pulmonary lymphangioleiomyomatosis?
Respiratory research 20110101
-
Immunosuppressant cytoprotection correlates with HMGB1 suppression in primary astrocyte cultures exposed to combined oxygen-glucose deprivation.
Pharmacological reports : PR 20110101
-
Efficacy of temsirolimus after previous treatment with sunitinib, sorafenib or everolimus in advanced renal cell cancer.
Oncology 20110101
-
Rapamycin ameliorates dystrophic phenotype in mdx mouse skeletal muscle.
Molecular medicine (Cambridge, Mass.) 20110101
-
Characterization of the metabolic phenotype of rapamycin-treated CD8+ T cells with augmented ability to generate long-lasting memory cells.
PloS one 20110101
-
Drug-eluting stent: importance of clinico-pathological correlations.
Circulation journal : official journal of the Japanese Circulation Society 20110101
-
[Changes of content of regulatory lymphocytes and concentration of soluble interleukine-2 receptor in blood of patients with ischemic heart disease after coronary artery angioplasty with implantation of stents with rapamycin covering].
Kardiologiia 20110101
-
Morphological and quantitative analysis of vascular wall and neointimal hyperplasia after coronary stenting: comparison of bare-metal and sirolimus-eluting stents using optical coherence tomography.
Circulation journal : official journal of the Japanese Circulation Society 20110101
-
Origin of restenosis after drug-eluting stent implantation in hyperglycemia is inflammatory cells and thrombus.
Journal of atherosclerosis and thrombosis 20110101
-
The role of mTOR inhibitors in renal diseases.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101
-
Effects of rapamycin on angiomyolipomas in patients with tuberous sclerosis.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101
-
Monitoring sirolimus levels: how does it affect the immunoassay used?
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101
-
Revascularization of left main coronary artery disease.
Cardiology in review 20110101
-
Estimating the threshold surface density of Gp120-CCR5 complexes necessary for HIV-1 envelope-mediated cell-cell fusion.
PloS one 20110101
-
Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in cancer stem cells.
Current medicinal chemistry 20110101
-
Targeting mTOR signaling pathway in ovarian cancer.
Current medicinal chemistry 20110101
-
Comparative study of clinical grade human tolerogenic dendritic cells.
Journal of translational medicine 20110101
-
Sirolimus may be associated with early recurrence of biliary obstruction in liver transplant patients undergoing endoscopic stenting of biliary strictures.
Annals of hepatology 20110101
-
Effects of cyclosporine, tacrolimus and rapamycin on renal calcium transport and vitamin D metabolism.
American journal of nephrology 20110101
-
The combination of RAD001 and NVP-BEZ235 exerts synergistic anticancer activity against non-small cell lung cancer in vitro and in vivo.
PloS one 20110101
-
Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN.
PloS one 20110101
-
Rapamycin-based inducible translocation systems for studying phagocytosis.
Methods in molecular biology (Clifton, N.J.) 20110101
-
Calcineurin inhibitor-based and free regimens have distinct gene expression patterns in subclinical graft fibrosis.
Annals of transplantation 20110101
-
Collapsing glomerulopathy in a renal transplant recipient: potential molecular mechanisms.
Annals of transplantation 20110101
-
[Rapamycin effect on senescence and autophagy processes in human cell lines].
Medicina 20110101
-
mTOR controls ovarian follicle growth by regulating granulosa cell proliferation.
PloS one 20110101
-
Determination of blood everolimus concentrations in kidney and liver transplant recipients using the sirolimus antibody conjugated magnetic immunoassay (ACMIA).
Clinical laboratory 20110101
-
Comparison of paclitaxel-, sirolimus-, and zotarolimus-eluting stents in patients with acute ST-segment elevation myocardial infarction and metabolic syndrome.
Circulation journal : official journal of the Japanese Circulation Society 20110101
-
Impact of acute gain on clinical outcomes of patients treated with sirolimus-eluting stent. - A sub-analysis study from the STLLR trial-.
Circulation journal : official journal of the Japanese Circulation Society 20110101
-
Very late sirolimus-eluting stent thrombosis due to stent fracture and late-acquired incomplete stent apposition detected on multislice computed tomography.
Circulation journal : official journal of the Japanese Circulation Society 20110101
-
Direct microscopic observation of striations in a fractured section of a sirolimus-eluting stent (Cypher Bx Velocity®) indicates induction of stent fracture by continuous shear stress.
International heart journal 20110101
-
Rapamycin inhibits the proliferation and apoptosis of gastric cancer cells by down regulating the expression of survivin.
Hepato-gastroenterology 20110101
-
Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer.
Journal of translational medicine 20110101
-
A periadventitial sirolimus-releasing mesh decreased intimal hyperplasia in a rabbit model.
Physiological research 20110101
-
Involvement of mTOR signaling in sphingosylphosphorylcholine-induced hypopigmentation effects.
Journal of biomedical science 20110101
-
Evolution of glomerular filtration rate, renal injury markers, anemia, and angiotensin blockers use after change from calcineurin inhibitors to sirolimus in transplant patients with neoplasia versus chronic allograft nephropathy.
Transplantation proceedings 20110101
-
Everolimus in clinical practice in long-term liver transplantation: an observational study.
Transplantation proceedings 20110101
-
Effectiveness and safety of everolimus in the treatment of autoimmune hepatitis related to anti-hepatitis C virus therapy after liver transplant: three case reports.
Transplantation proceedings 20110101
-
Conversion to everolimus in liver transplant patients with renal dysfunction.
Transplantation proceedings 20110101
-
Long-term use of everolimus in lung transplant patients.
Transplantation proceedings 20110101
-
Cutaneous and mucosal aphthosis during temsirolimus therapy for advanced renal cell carcinoma: review of cutaneous and mucosal side effects of mTOR inhibitors.
Dermatology (Basel, Switzerland) 20110101
-
SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 MAP kinase inhibition.
PloS one 20110101
-
Endothelial-like cells in chronic thromboembolic pulmonary hypertension: crosstalk with myofibroblast-like cells.
Respiratory research 20110101
-
Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis.
BMC cancer 20110101
-
[Mass spectrometry-based quantitative analysis and biomarker discovery].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101
-
Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1.
PloS one 20110101
-
Calcineurin inhibitor-induced and Ras-mediated overexpression of VEGF in renal cancer cells involves mTOR through the regulation of PRAS40.
PloS one 20110101
-
The peptidyl prolyl isomerase Rrd1 regulates the elongation of RNA polymerase II during transcriptional stresses.
PloS one 20110101
-
Inhibition of radiation induced migration of human head and neck squamous cell carcinoma cells by blocking of EGF receptor pathways.
BMC cancer 20110101
-
c-Myc dependent expression of pro-apoptotic Bim renders HER2-overexpressing breast cancer cells dependent on anti-apoptotic Mcl-1.
Molecular cancer 20110101
-
Chikungunya triggers an autophagic process which promotes viral replication.
Virology journal 20110101
-
Molecular mechanisms of l-DOPA-induced dyskinesia.
International review of neurobiology 20110101
-
Economic evaluation of everolimus versus sorafenib for the treatment of metastatic renal cell carcinoma after failure of first-line sunitinib.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20110101
-
Multicenter phase 2 trial of sirolimus for tuberous sclerosis: kidney angiomyolipomas and other tumors regress and VEGF- D levels decrease.
PloS one 20110101
-
Involvement of mTOR in CXCL12 mediated T cell signaling and migration.
PloS one 20110101
-
The activation of the p53 pathway by the AMP mimetic AICAR is reduced by inhibitors of the ATM or mTOR kinases.
Mechanisms of ageing and development 20110101
-
Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells.
PloS one 20110101
-
The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation.
Molecular systems biology 20110101
-
Ezetimibe in sirolimus-associated hyperlipidemia: to add or not to add to statins?
Annals of transplantation 20110101
-
The combination of gefitinib and RAD001 inhibits growth of HER2 overexpressing breast cancer cells and tumors irrespective of trastuzumab sensitivity.
BMC cancer 20110101
-
Temporal regulation of rapamycin on memory CTL programming by IL-12.
PloS one 20110101
-
Anti-proliferation effects of Sirolimus sustained delivery film in rabbit glaucoma filtration surgery.
Molecular vision 20110101
-
Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits.
PloS one 20110101
-
Human glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 mouse model of ALS.
PloS one 20110101
-
Elimination of proliferating cells unmasks the shift from senescence to quiescence caused by rapamycin.
PloS one 20110101
-
A mechanism for synergy with combined mTOR and PI3 kinase inhibitors.
PloS one 20110101
-
Retrospective comparison of the clinical and angiographic outcomes of the sirolimus-eluting stent and the bare-metal stent in 2031 nonrandomized consecutive de novo native coronary lesions.
Internal medicine (Tokyo, Japan) 20110101
-
Neoadjuvant chemotherapy and targeted therapies: a promising strategy.
Journal of the National Cancer Institute. Monographs 20110101
-
Combined treatment with antioxidants and immunosuppressants on cytokine release by human peripheral blood mononuclear cells - chemically injured keratocyte reaction.
Molecular vision 20110101
-
Mapping the interaction of Snf1 with TORC1 in Saccharomyces cerevisiae.
Molecular systems biology 20110101
-
[Metastatic renal cell carcinoma treated with everolimus--data from the RENIS Clinical Registry].
Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20110101
-
Targeting notch pathway enhances rapamycin antitumor activity in pancreas cancers through PTEN phosphorylation.
Molecular cancer 20110101
-
Concurrent HDAC and mTORC1 inhibition attenuate androgen receptor and hypoxia signaling associated with alterations in microRNA expression.
PloS one 20110101
-
Everolimus and long acting octreotide as a volume reducing treatment of polycystic livers (ELATE): study protocol for a randomized controlled trial.
Trials 20110101
-
S6K1 and 4E-BP1 are independent regulated and control cellular growth in bladder cancer.
PloS one 20110101
-
Giant bilateral renal angiomyolipomas and lymphangioleiomyomatosis presenting after two successive pregnancies successfully treated with surgery and rapamycin.
TheScientificWorldJournal 20110101
-
Phase I-II study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell cancer.
BMC cancer 20110101
-
Evaluation of an AAV2-based rapamycin-regulated glial cell line-derived neurotrophic factor (GDNF) expression vector system.
PloS one 20110101
-
Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with paclitaxel infusion.
PloS one 20110101
-
Transient mTOR inhibition facilitates continuous growth of liver tumors by modulating the maintenance of CD133+ cell populations.
PloS one 20110101
-
Therapy for aplastic anemia.
Hematology. American Society of Hematology. Education Program 20110101
-
Enhanced bioavailability of sirolimus via preparation of solid dispersion nanoparticles using a supercritical antisolvent process.
International journal of nanomedicine 20110101
-
Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation.
PloS one 20110101
-
Two cases of everolimus-associated interstitial pneumonia in patients with renal cell carcinoma.
Internal medicine (Tokyo, Japan) 20110101
-
Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway.
PloS one 20110101
-
Progressive lymphangiomatosis and Gorham's disease: case report and clinical implications.
Lymphatic research and biology 20110101
-
Pulmonary embolism and reactivation of tuberculosis during everolimus therapy in a kidney transplant recipient.
Annals of transplantation 20110101
-
Sensitivity of global translation to mTOR inhibition in REN cells depends on the equilibrium between eIF4E and 4E-BP1.
PloS one 20110101
-
Rapamycin prevents endothelial cell migration by inhibiting the endothelial-to-mesenchymal transition and matrix metalloproteinase-2 and -9: an in vitro study.
Molecular vision 20110101
-
Procedure for determination of immunosuppressive drugs in whole blood with liquid chromatography-isotope dilution mass spectrometry.
Clinical laboratory 20110101
-
Resveratrol inhibits protein translation in hepatic cells.
PloS one 20110101
-
Compassionate use of everolimus in a patient with a neuroendocrine tumor: a case report and discussion of the literature.
Oncology research 20110101
-
Combination effects of paclitaxel with signaling inhibitors in endometrial cancer cells.
Asian Pacific journal of cancer prevention : APJCP 20110101
-
[Efficiency of medical versus endovascular treatment using drug-eluting stents in coronary heart disease patients with extensive lesion of the coronary bed].
Vestnik rentgenologii i radiologii 20110101
-
[Post transplant lymphoproliferative disorder (PTLD)--10 years follow-up].
Przeglad lekarski 20110101
-
Acute thrombosis of drug eluting stent following protamine: a case report.
Indian heart journal 20110101
-
Two-year outcomes in thoracic transplant recipients after conversion to everolimus with reduced calcineurin inhibitor within a multicenter, open-label, randomized trial.
Transplantation 20101227
-
The International Registry on Hand and Composite Tissue Transplantation.
Transplantation 20101227
-
Anti-BK virus mechanisms of sirolimus and leflunomide alone and in combination: toward a new therapy for BK virus infection.
Transplantation 20101227
-
Hsp90 and environmental stress transform the adaptive value of natural genetic variation.
Science (New York, N.Y.) 20101224
-
Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways.
Blood 20101223
-
RAD001 shows activity against gastric cancer cells and overcomes 5-FU resistance by downregulating thymidylate synthase.
Cancer letters 20101218
-
Development of a dot-blot assay for screening monoclonal antibodies to low-molecular-mass drugs.
Analytical biochemistry 20101215
-
Treatment of childhood kaposiform hemangioendothelioma with sirolimus.
Pediatric blood & cancer 20101215
-
Temsirolimus for metastatic desmoplastic small round cell tumor.
Pediatric blood & cancer 20101215
-
Immunosuppression involving soluble CD83 induces tolerogenic dendritic cells that prevent cardiac allograft rejection.
Transplantation 20101215
-
Prolidase-dependent regulation of TGF β (corrected) and TGF β receptor expressions in human skin fibroblasts.
European journal of pharmacology 20101215
-
Unequal in the absence of death: a novel screen identifies cytotoxic compounds selective for cells with activated Akt.
Cancer biology & therapy 20101215
-
Identification of Akt-selective cytotoxic compounds that enhance cytotoxic responses to rapamycin.
Cancer biology & therapy 20101215
-
Zoledronic acid potentiates mTOR inhibition and abolishes the resistance of osteosarcoma cells to RAD001 (Everolimus): pivotal role of the prenylation process.
Cancer research 20101215
-
Isolation and expansion of human natural T regulatory cells for cellular therapy.
Journal of immunological methods 20101215
-
Mammalian target of rapamycin: biological function and target for novel anticancer agents.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101215
-
Increasing healthy lifespan by suppressing aging in our lifetime: preliminary proposal.
Cell cycle (Georgetown, Tex.) 20101215
-
Pemetrexed indirectly activates the metabolic kinase AMPK in human carcinomas.
Cancer research 20101215
-
BRAF mutation-selective inhibition of thyroid cancer cells by the novel MEK inhibitor RDEA119 and genetic-potentiated synergism with the mTOR inhibitor temsirolimus.
International journal of cancer 20101215
-
Outcomes in diabetic and nondiabetic patients treated with everolimus- or paclitaxel-eluting stents: results from the SPIRIT IV clinical trial (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System).
Journal of the American College of Cardiology 20101214
-
An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness.
Immunity 20101214
-
C60(Nd) nanoparticles enhance chemotherapeutic susceptibility of cancer cells by modulation of autophagy.
Nanotechnology 20101210
-
GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28- CD8+ T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression.
Blood 20101209
-
Drug-eluting versus bare-metal stents in large coronary arteries.
The New England journal of medicine 20101209
-
Combinations of mTORC1 inhibitor RAD001 with gemcitabine and paclitaxel for treating non-Hodgkin lymphoma.
Cancer letters 20101208
-
Copper-doxorubicin as a nanoparticle cargo retains efficacy with minimal toxicity.
Molecular pharmaceutics 20101206
-
Targeted drug delivery to lymphocytes: a route to site-specific immunomodulation?
Molecular pharmaceutics 20101206
-
Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity.
The Journal of biological chemistry 20101203
-
Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells.
Nature 20101202
-
Reflex sympathetic dystrophy in patients with metastatic renal cell carcinoma treated with everolimus.
Investigational new drugs 20101201
-
TAE226-mediated inhibition of focal adhesion kinase interferes with tumor angiogenesis and vasculogenesis.
Investigational new drugs 20101201
-
Pharmacodynamic evaluation of temsirolimus in patients with newly diagnosed advanced-stage head and neck squamous cell carcinoma.
Head & neck 20101201
-
Mammalian target of rapamycin signaling in the spinal cord is required for neuronal plasticity and behavioral hypersensitivity associated with neuropathy in the rat.
The journal of pain : official journal of the American Pain Society 20101201
-
Intrinsic and extrinsic mechanisms of oocyte loss.
Molecular human reproduction 20101201
-
Quantitative determination of sirolimus in dog blood using liquid chromatography-tandem mass spectrometry, and its applications to pharmacokinetic studies.
Journal of pharmaceutical and biomedical analysis 20101201
-
A phase 2 study of the oral mammalian target of rapamycin inhibitor, everolimus, in patients with recurrent endometrial carcinoma.
Cancer 20101201
-
TORC1 kinase and the S-phase cyclin Clb5 collaborate to promote mitotic spindle assembly and DNA replication in S. cerevisiae.
Current genetics 20101201
-
Sirolimus for calcineurin inhibitors in organ transplantation: contra.
Kidney international 20101201
-
Dysregulation of epithelial Na+ absorption induced by inhibition of the kinases TORC1 and TORC2.
British journal of pharmacology 20101201
-
Autosomal dominant polycystic kidney disease and mTOR inhibitors: the narrow road between hope and disappointment.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101201
-
Mammalian target of rapamycin inhibition abrogates insulin-mediated mammary tumor progression in type 2 diabetes.
Endocrine-related cancer 20101201
-
Regulation of gastric hormones by systemic rapamycin.
Peptides 20101201
-
Comparison of three-year clinical outcomes between sirolimus-versus paclitaxel-eluting stents in diabetic patients: prospective randomized multicenter trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101201
-
Mammalian target of rapamycin signaling activation patterns in neuroendocrine tumors of the lung.
Endocrine-related cancer 20101201
-
Silymarin inhibits endothelial progenitor cells' senescence and protects against the antiproliferative activity of rapamycin: preliminary study.
Journal of cardiovascular pharmacology 20101201
-
Curcumin inhibits carcinogen and nicotine-induced Mammalian target of rapamycin pathway activation in head and neck squamous cell carcinoma.
Cancer prevention research (Philadelphia, Pa.) 20101201
-
mTOR inhibitor rapamycin suppresses striatal post-ischemic LTP.
Experimental neurology 20101201
-
Crush stenting with drug-eluting stents: relevance of coronary bifurcation lesion location on angiographic and clinical outcomes.
Clinical cardiology 20101201
-
Dual blocking of mTor and PI3K elicits a prodifferentiation effect on glioblastoma stem-like cells.
Neuro-oncology 20101201
-
The potential benefits of rapamycin on renal function, tolerance, fibrosis, and malignancy following transplantation.
Kidney international 20101201
-
Rapamycin inhibits cell proliferation in type I and type II endometrial carcinomas: a search for biomarkers of sensitivity to treatment.
Gynecologic oncology 20101201
-
Third-line sorafenib after sequential therapy with sunitinib and mTOR inhibitors in metastatic renal cell carcinoma.
European urology 20101201
-
Inhibition of voltage-gated K+ channels in dendritic cells by rapamycin.
American journal of physiology. Cell physiology 20101201
-
mTOR-inhibition in metastatic renal cell carcinoma. Focus on temsirolimus: a review.
Minerva urologica e nefrologica = The Italian journal of urology and nephrology 20101201
-
Mechanical stretch activates signaling events for protein translation initiation and elongation in C2C12 myoblasts.
Molecules and cells 20101201
-
Phase I study of everolimus plus weekly paclitaxel and trastuzumab in patients with metastatic breast cancer pretreated with trastuzumab.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101201
-
Cellular and molecular changes associated with inhibitory effect of pioglitazone on neointimal growth in patients with type 2 diabetes after zotarolimus-eluting stent implantation.
Arteriosclerosis, thrombosis, and vascular biology 20101201
-
Determination of cyclosporine, tacrolimus, sirolimus and everolimus by liquid chromatography coupled to electrospray ionization and tandem mass spectrometry: assessment of matrix effects and assay performance.
Scandinavian journal of clinical and laboratory investigation 20101201
-
mTORC1 inhibition via rapamycin promotes triacylglycerol lipolysis and release of free fatty acids in 3T3-L1 adipocytes.
Lipids 20101201
-
Phase II study of everolimus (RAD001) in previously treated small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 20101201
-
Six-month results of the NEVO Res-Elution I (NEVO RES-I) trial: a randomized, multicenter comparison of the NEVO sirolimus-eluting coronary stent with the TAXUS Liberté paclitaxel-eluting stent in de novo native coronary artery lesions.
Circulation. Cardiovascular interventions 20101201
-
Lysosomal accumulation of mTOR is enhanced by rapamycin.
Histochemistry and cell biology 20101201
-
Developmental pharmacogenetics of immunosuppressants in pediatric organ transplantation.
Therapeutic drug monitoring 20101201
-
Development of a validated high-throughput LC-ESI-MS method for determination of sirolimus on dried blood spots.
Biomedical chromatography : BMC 20101201
-
Protein kinase Mzeta is essential for the induction and maintenance of dopamine-induced long-term potentiation in apical CA1 dendrites.
Learning & memory (Cold Spring Harbor, N.Y.) 20101201
-
The Kounis syndrome in everolimus-eluting stents and paclitaxel-eluting stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101201
-
Safety and efficacy of sirolimus-eluting stent implantation in patients with acute coronary syndrome in the real world.
The American journal of cardiology 20101201
-
Effect of FKBP65, a putative elastin chaperone, on the coacervation of tropoelastin in vitro.
Biochemistry and cell biology = Biochimie et biologie cellulaire 20101201
-
High glycemic stenting menu.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101201
-
Do mTOR inhibitors still have a future in ADPKD?
Nature reviews. Nephrology 20101201
-
Sirolimus and kidney transplantation: unraveling an inflammatory affair.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101201
-
Comparative transcriptional and phenotypic peripheral blood analysis of kidney recipients under cyclosporin A or sirolimus monotherapy.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101201
-
Recurrent stent fracture: first reported image of everolimus-eluting stent fracture leading to recurrent restenosis in cardiac allograft vasculopathy.
The Journal of invasive cardiology 20101201
-
Proteinuria among primarily sirolimus treated live-donor renal transplant recipients' long-term experience.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20101201
-
Rapamycin inhibits anal carcinogenesis in two preclinical animal models.
Cancer prevention research (Philadelphia, Pa.) 20101201
-
mTOR and its link to the picture of Dorian Gray - re-activation of mTOR promotes aging.
Aging 20101201
-
Intracellular amino acid sensing and mTORC1-regulated growth: new ways to block an old target?
Current opinion in investigational drugs (London, England : 2000) 20101201
-
Long-term outcome of very early cyclosporine minimization and de novo everolimus therapy in kidney transplant recipients: a pharmacokinetic guided approach.
Transplantation proceedings 20101201
-
Conversion from calcineurin inhibitor to either mycophenolate mofetil or sirolimus improves renal function in liver transplant recipients with chronic kidney disease: results of a prospective randomized trial.
Transplantation proceedings 20101201
-
Individualizing early use of sirolimus in renal transplantation.
Transplantation proceedings 20101201
-
Potential use of rapamycin in HIV infection.
British journal of clinical pharmacology 20101201
-
Unilateral upper limb lympatic obstruction and severe lymphoedema in a patient on long-term sirolimus.
Nephrology (Carlton, Vic.) 20101201
-
[Effect of rapamycin on proliferation of acute myeloid leukemia cell lines HL-60 and HL-60/VCR].
Zhongguo shi yan xue ye xue za zhi 20101201
-
[mTOR, the mammalian target of rapamycin].
Medecine sciences : M/S 20101201
-
More than 4 years of progression-free survival in a patient with metastatic renal cell carcinoma treated sequentially with sunitinib, everolimus, sorafenib, and temsirolimus.
Anticancer research 20101201
-
DNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescence.
Aging 20101201
-
[A case report of very late thrombosis in two sirolimus-eluting stents].
Zhonghua xin xue guan bing za zhi 20101201
-
[Down-regulation of mTOR activity and survivin expression during tamoxifen-induced apoptosis in hepatoblastoma cells].
Zhonghua zhong liu za zhi [Chinese journal of oncology] 20101201
-
Clinical follow-up 3 years after everolimus- and paclitaxel-eluting stents: a pooled analysis from the SPIRIT II (A Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System in the Treatment of Patients With De Novo Native Coronary Artery Lesions) and SPIRIT III (A Clinical Evaluation of the Investigational Device XIENCE V Everolimus Eluting Coronary Stent System [EECSS] in the Treatment of Subjects With De Novo Native Coronary Artery Lesions) randomized trials.
JACC. Cardiovascular interventions 20101201
-
Comparison of everolimus-eluting and paclitaxel-eluting coronary stents in patients undergoing multilesion and multivessel intervention: the SPIRIT III (A Clinical Evaluation of the Investigational Device XIENCE V Everolimus Eluting Coronary Stent System [EECSS] in the Treatment of Subjects With De Novo Native Coronary Artery Lesions) and SPIRIT IV (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System in the Treatment of Subjects With De Novo Native Coronary Artery Lesions) randomize
JACC. Cardiovascular interventions 20101201
-
Long-term clinical outcomes with zotarolimus-eluting versus bare-metal coronary stents.
JACC. Cardiovascular interventions 20101201
-
Temsirolimus and mantle cell lymphoma. Highly toxic, limited efficacy.
Prescrire international 20101201
-
High entrapment efficiency of chitosan/polylactic acid/tripolyphotspate nanosized microcapsules for rapamycin by an emulsion-evaporation approach.
Journal of biomedical nanotechnology 20101201
-
The AXXESSâ„¢ self-expanding biolimus A9â„¢ eluting stent system for coronary bifurcation lesions.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101201
-
Dedicated everolimus-eluting side branch access system: XIENCE SBA.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101201
-
Side branch occlusion with everolimus-eluting and paclitaxel-eluting stents: three-year results from the SPIRIT III randomised trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101201
-
Intracoronary optical coherence tomography and histology at 1 month and 2, 3, and 4 years after implantation of everolimus-eluting bioresorbable vascular scaffolds in a porcine coronary artery model: an attempt to decipher the human optical coherence tomography images in the ABSORB trial.
Circulation 20101130
-
Evaluation of the second generation of a bioresorbable everolimus drug-eluting vascular scaffold for treatment of de novo coronary artery stenosis: six-month clinical and imaging outcomes.
Circulation 20101130
-
Activation of phosphatidylinositol 3-kinase/Akt-mammalian target of Rapamycin signaling pathway in the hippocampus is essential for the acquisition of morphine-induced place preference in rats.
Neuroscience 20101124
-
Sirolimus plus sorafenib in treating HCC recurrence after liver transplantation: a case report.
World journal of gastroenterology 20101121
-
Bevacizumab and everolimus in renal cancer: a rational way forward.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101120
-
Sirolimus- vs. paclitaxel-eluting stents in patients undergoing off-label percutaneous coronary intervention.
International journal of cardiology 20101119
-
Multiple cellular proteins modulate the dynamics of K-ras association with the plasma membrane.
Biophysical journal 20101117
-
Roles of autophagy in cetuximab-mediated cancer therapy against EGFR.
Autophagy 20101116
-
B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer.
Cancer cell 20101116
-
A collection of caged compounds for probing roles of local translation in neurobiology.
Bioorganic & medicinal chemistry 20101115
-
Sex-specific outcomes following revascularization with zotarolimus-eluting stents: comparison of angiographic and late-term clinical results.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101115
-
Combination of temsirolimus (CCI-779) with chemoradiation in newly diagnosed glioblastoma multiforme (GBM) (NCCTG trial N027D) is associated with increased infectious risks.
Clinical cancer research : an official journal of the American Association for Cancer Research 20101115
-
Comparison of five-year outcome of octogenarians undergoing percutaneous coronary intervention with drug-eluting versus bare-metal stents (from the RESEARCH and T-SEARCH Registries).
The American journal of cardiology 20101115
-
Impact of moderate renal insufficiency on restenosis and adverse clinical events after sirolimus-eluting and bare metal stent implantation (from the SIRIUS trials).
The American journal of cardiology 20101115
-
Mammalian target of rapamycin-dependent acinar cell neoplasia after inactivation of Apc and Pten in the mouse salivary gland: implications for human acinic cell carcinoma.
Cancer research 20101115
-
Gender medicine and drug eluting coronary stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101115
-
A stress-responsive system for mitochondrial protein degradation.
Molecular cell 20101112
-
Akt and autophagy cooperate to promote survival of drug-resistant glioma.
Science signaling 20101109
-
Sirolimus-eluting versus bare-metal stent implantation in patients with ostial lesions.
International journal of cardiology 20101105
-
Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis.
The New England journal of medicine 20101104
-
Precise control of protein concentration in living cells.
Angewandte Chemie (International ed. in English) 20101102
-
Inducible somatic oocyte destruction in response to rapamycin requires wild-type regulation of follicle cell epithelial polarity.
Cell death and differentiation 20101101
-
Cyclin D1 and cyclin D3 show divergent responses to distinct mitogenic stimulation.
Journal of cellular physiology 20101101
-
Evidence for cell cycle-dependent, rapamycin-resistant phosphorylation of ribosomal protein S6 at S240/244.
Amino acids 20101101
-
Bortezomib and sirolimus inhibit the chronic active antibody-mediated rejection in experimental renal transplantation in the rat.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101101
-
Supplementing L-leucine to a low-protein diet increases tissue protein synthesis in weanling pigs.
Amino acids 20101101
-
Efficacy and safety of de novo or early everolimus with low cyclosporine in deceased-donor kidney transplant recipients at specified risk of delayed graft function: 12-month results of a randomized, multicenter trial.
Transplant international : official journal of the European Society for Organ Transplantation 20101101
-
Evaluation of the effects of everolimus-eluting and paclitaxel-eluting stents on target lesions with jailed side branches: 2-year results from the SPIRIT III randomized trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101
-
Comparative effects of sirolimus and cyclosporin on conduit arteries endothelial function in kidney recipients.
Transplant international : official journal of the European Society for Organ Transplantation 20101101
-
Posttranslational regulation of membrane type 1-matrix metalloproteinase (MT1-MMP) in mouse PTEN null prostate cancer cells: Enhanced surface expression and differential O-glycosylation of MT1-MMP.
Biochimica et biophysica acta 20101101
-
Low-dose rapamycin reduces kidney volume angiomyolipomas and prevents the loss of renal function in a patient with tuberous sclerosis complex.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101101
-
Efficacy of everolimus eluting stent implantation in patients with calcified coronary culprit lesions: two-year angiographic and three-year clinical results from the SPIRIT II study.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101
-
Maintenance immunosuppressive therapy with everolimus preserves humoral immune responses.
Kidney international 20101101
-
Sirolimus immunosuppression for graft-versus-host disease prophylaxis and therapy: an update.
Current opinion in hematology 20101101
-
Usefulness of sirolimus-based immunosuppression in ameliorating pre-transplant renal dysfunction in patients with Chagas' heart disease.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20101101
-
Concurrent involved field radiation therapy and temsirolimus in refractory mantle cell lymphoma (MCL).
American journal of hematology 20101101
-
Efficacy and safety/toxicity study of recombinant vaccinia virus JX-594 in two immunocompetent animal models of glioma.
Molecular therapy : the journal of the American Society of Gene Therapy 20101101
-
Lipids and renal cystic disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101101
-
Childhood rhabdomyosarcoma: new insight on biology and treatment.
Current oncology reports 20101101
-
Maintenance and consolidation strategies in non-Hodgkin's lymphoma: A review of the data.
Current oncology reports 20101101
-
Increased levels of p70S6 phosphorylation in the G93A mouse model of Amyotrophic Lateral Sclerosis and in valine-exposed cortical neurons in culture.
Experimental neurology 20101101
-
Temsirolimus has activity in non-mantle cell non-Hodgkin's lymphoma subtypes: The University of Chicago phase II consortium.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101101
-
An MHC-defined primate model reveals significant rejection of bone marrow after mixed chimerism induction despite full MHC matching.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101101
-
Antitumor effect of temsirolimus against oral squamous cell carcinoma associated with bone destruction.
Molecular cancer therapeutics 20101101
-
Comparisons of the effects of stent eccentricity on the neointimal hyperplasia between sirolimus-eluting stent versus paclitaxel-eluting stent.
Yonsei medical journal 20101101
-
Repeated sirolimus-eluting stent implantation to treat sirolimus-eluting stent and bare-metal stent restenosis.
Circulation journal : official journal of the Japanese Circulation Society 20101101
-
Comparison of vascular response to zotarolimus-eluting stent vs paclitaxel-eluting stent implantation: pooled IVUS results from the ZoMaxx I and II trials.
Circulation journal : official journal of the Japanese Circulation Society 20101101
-
Distinct patterns of autophagy evoked by two benzoxazine derivatives in vascular endothelial cells.
Autophagy 20101101
-
STAT3 transcriptional factor activated by reactive oxygen species induces IL6 in starvation-induced autophagy of cancer cells.
Autophagy 20101101
-
Inhibition of the mammalian target of rapamycin promotes cyclic AMP-induced differentiation of NG108-15 cells.
Autophagy 20101101
-
Three-month dual antiplatelet therapy after implantation of zotarolimus-eluting stents: the DATE (Duration of Dual Antiplatelet Therapy AfterImplantation of Endeavor Stent) registry.
Circulation journal : official journal of the Japanese Circulation Society 20101101
-
The use of sirolimus as a rescue therapy in pediatric intestinal transplant recipients.
Pediatric transplantation 20101101
-
Activation of Atg1 kinase in autophagy by regulated phosphorylation.
Autophagy 20101101
-
Autophagy: a target for retinoic acids.
Autophagy 20101101
-
Bevacizumab for metastatic renal cell carcinoma: a monoclonal antibody in a sea of small molecules.
Expert opinion on biological therapy 20101101
-
Pharmacologic eigenvalues: beating the rap on bone marrow failure.
The Journal of clinical investigation 20101101
-
Phase I study of the oral mammalian target of rapamycin inhibitor everolimus (RAD001) in Japanese patients with relapsed or refractory non-Hodgkin lymphoma.
International journal of hematology 20101101
-
Warning: this report does not address heavily calcified coronary arteries.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101
-
More openness and a little less strut: two good ideas for stents and the people who implant them.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101
-
Mammalian target of rapamycin complex 1 is involved in differentiation of regenerating myofibers in vivo.
Muscle & nerve 20101101
-
Transplantation: can sirolimus prevent skin cancer in transplant recipients?
Nature reviews. Nephrology 20101101
-
Comparison of outcomes in patients with insulin-dependent versus non-insulin dependent diabetes mellitus receiving drug-eluting stents (from the first phase of the prospective multicenter German DES.DE registry).
The American journal of cardiology 20101101
-
Lack of effect of oral beta-blocker therapy at discharge on long-term clinical outcomes of ST-segment elevation acute myocardial infarction after primary percutaneous coronary intervention.
The American journal of cardiology 20101101
-
Could Paclitaxel-eluting stents be superior to sirolimus-eluting stents for the treatment of saphenous vein graft lesions?
The American journal of cardiology 20101101
-
Conditionally controlling nuclear trafficking in yeast by chemical-induced protein dimerization.
Nature protocols 20101101
-
Differing effects of systemically administered rapamycin on consolidation and reconsolidation of context vs. cued fear memories.
Learning & memory (Cold Spring Harbor, N.Y.) 20101101
-
Impact of insulin-treated diabetes and hemodialysis on long-term clinical outcomes following sirolimus-eluting stent deployment. Insights from a sub-study of the Cypher Stent Japan Post-Marketing Surveillance(Cypher J-PMS) Registry.
Circulation journal : official journal of the Japanese Circulation Society 20101101
-
Long-term follow-up of the randomised controlled trial to evaluate the safety and efficacy of the zotarolimus-eluting driver coronary stent in de novo native coronary artery lesions: five year outcomes in the ENDEAVOR II study.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101101
-
Strut tissue coverage and endothelial cell coverage: a comparison between bare metal stent platforms and platinum chromium stents with and without everolimus-eluting coating.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101101
-
A phase I dose-escalation study to evaluate safety and tolerability of sorafenib combined with sirolimus in patients with advanced solid cancer.
British journal of cancer 20101101
-
The effect of shear stress on neointimal response following sirolimus- and paclitaxel-eluting stent implantation compared with bare-metal stents in humans.
JACC. Cardiovascular interventions 20101101
-
A comparison of the conformability of everolimus-eluting bioresorbable vascular scaffolds to metal platform coronary stents.
JACC. Cardiovascular interventions 20101101
-
In vivo assessment of local intravascular hemodynamics and arterial morphology to investigate vascular outcomes: a growing field coming of age.
JACC. Cardiovascular interventions 20101101
-
Neovascular microchannels in sirolimus-eluting stent occlusion at late phase.
JACC. Cardiovascular interventions 20101101
-
Low-dose calcineurin inhibitor regimen combined with mammalian target of rapamycin inhibitors preserves kidney functions in renal transplant recipients without allograft nephropathy.
Transplantation proceedings 20101101
-
Malignancies after heart transplantation: incidence, risk factors, and effects of calcineurin inhibitor withdrawal.
Transplantation proceedings 20101101
-
Common occurrence of everolimus-associated aphthous stomatitis in Japanese heart transplant recipients.
Transplantation proceedings 20101101
-
Use of genetically modified allograft to deliver local immunomodulatory molecule with minimal systemic toxicity in a rat model of allogeneic skin flap transplantation.
Transplantation proceedings 20101101
-
Recurrent non-melanoma skin cancer: remission of field cancerization after conversion from calcineurin inhibitor- to proliferation signal inhibitor-based immunosuppression in a cardiac transplant recipient.
Transplantation proceedings 20101101
-
Immunoregulation and tolerance.
Transplantation proceedings 20101101
-
Can we eliminate both calcineurin inhibitors and steroids?
Transplantation proceedings 20101101
-
Rationale for using belatacept in combination with sirolimus.
Transplantation proceedings 20101101
-
Can immunosuppressive strategies be used to reduce cancer risk in renal transplant patients?
Transplantation proceedings 20101101
-
Clinical insights for cancer outcomes in renal transplant patients.
Transplantation proceedings 20101101
-
Regression of left ventricular hypertrophy in kidney transplant recipients: the potential role for inhibition of mammalian target of rapamycin.
Transplantation proceedings 20101101
-
Impact of mammalian target of rapamycin inhibition on autosomal-dominant polycystic kidney disease.
Transplantation proceedings 20101101
-
The therapy of kidney cancer with biomolecular drugs.
Cancer treatment reviews 20101101
-
Biological targeted therapies in patients with advanced enteropancreatic neuroendocrine carcinomas.
Cancer treatment reviews 20101101
-
FK506 binding proteins as targets in anticancer therapy.
Anti-cancer agents in medicinal chemistry 20101101
-
Ras homolog enriched in brain (Rheb) enhances apoptotic signaling.
The Journal of biological chemistry 20101029
-
Descending serotonergic facilitation mediated by spinal 5-HT3 receptors engages spinal rapamycin-sensitive pathways in the rat.
Neuroscience letters 20101029
-
Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling.
Immunity 20101029
-
mTOR inhibition by everolimus counteracts VEGF induction by sunitinib and improves anti-tumor activity against gastric cancer in vivo.
Cancer letters 20101028
-
Assessment of efficacy and safety of FK778 in comparison with standard care in renal transplant recipients with untreated BK nephropathy.
Transplantation 20101027
-
[New possibilities of targeted therapy in the treatment of hepatocellular carcinoma with the help of molecular biology].
Orvosi hetilap 20101024
-
Phase I studies of drug combinations.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101020
-
Phase IB study of the mTOR inhibitor ridaforolimus with capecitabine.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101020
-
Generation of high rapamycin producing strain via rational metabolic pathway-based mutagenesis and further titer improvement with fed-batch bioprocess optimization.
Biotechnology and bioengineering 20101015
-
Rapamycin suppresses the expansion and differentiation of porcine neonatal pancreas cell clusters.
Transplantation 20101015
-
Combined administration of a mutant TGF-beta1/Fc and rapamycin promotes induction of regulatory T cells and islet allograft tolerance.
Journal of immunology (Baltimore, Md. : 1950) 20101015
-
Survival benefit with proapoptotic molecular and pathologic responses from dual targeting of mammalian target of rapamycin and epidermal growth factor receptor in a preclinical model of pancreatic neuroendocrine carcinogenesis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101010
-
Small tumors, intermediate models, big hopes.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101010
-
Steady-state kinetic and inhibition studies of the mammalian target of rapamycin (mTOR) kinase domain and mTOR complexes.
Biochemistry 20101005
-
Comparison of zotarolimus-eluting stents with sirolimus- and paclitaxel-eluting stents for coronary revascularization: the ZEST (comparison of the efficacy and safety of zotarolimus-eluting stent with sirolimus-eluting and paclitaxel-eluting stent for coronary lesions) randomized trial.
Journal of the American College of Cardiology 20101005
-
Tacrolimus-eluting carbon-coated stents versus sirolimus-eluting stents for prevention of symptom-driven clinical end points.
Clinical research in cardiology : official journal of the German Cardiac Society 20101001
-
Rapamycin sensitizes Akt inhibition in malignant human breast epithelial cells.
Cancer letters 20101001
-
Autoimmune cytopaenia after paediatric intestinal transplantation: a case series.
Transplant international : official journal of the European Society for Organ Transplantation 20101001
-
Early withdrawal of calcineurin inhibitors and everolimus monotherapy in de novo liver transplant recipients preserves renal function.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101001
-
A phase I-II study of everolimus (RAD001) in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors.
Annals of oncology : official journal of the European Society for Medical Oncology 20101001
-
Sirolimus oral ulcer with Cedecea davisae superinfection.
Transplant infectious disease : an official journal of the Transplantation Society 20101001
-
Sirolimus addition to tacrolimus-based immunosuppression induces complete remission of post-transplant lymphoproliferative disorder in a liver transplant recipient.
Transplant international : official journal of the European Society for Organ Transplantation 20101001
-
Amyloid-beta oligomers impair fear conditioned memory in a calcineurin-dependent fashion in mice.
Journal of neuroscience research 20101001
-
Immunosuppressive therapy and infection after kidney transplantation.
Transplant infectious disease : an official journal of the Transplantation Society 20101001
-
Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy.
Neurobiology of disease 20101001
-
Influence of combined treatment of low dose rapamycin and cyclosporin A on corneal allograft survival.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20101001
-
Activation of mammalian target of rapamycin signaling in spatial learning.
Neuroscience research 20101001
-
Gingival overgrowth in subjects under immunosuppressive regimens based on cyclosporine, tacrolimus, or sirolimus.
Journal of clinical periodontology 20101001
-
Novel mechanism of reducing tumourigenesis: upregulation of the DNA repair enzyme OGG1 by rapamycin-mediated AMPK activation and mTOR inhibition.
European journal of cancer (Oxford, England : 1990) 20101001
-
Evaluation of two sirolimus assays using the ARCHITECT-i1000(®) CMIA or RxL(®) ACMIA methods in comparison with the IMx(®) MEIA method.
Clinical chemistry and laboratory medicine 20101001
-
β-Amyloid regulates leptin expression and tau phosphorylation through the mTORC1 signaling pathway.
Journal of neurochemistry 20101001
-
Activation of the mammalian target of rapamycin signaling pathway in hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 20101001
-
Sirolimus attenuates disease progression in an orthologous mouse model of human autosomal dominant polycystic kidney disease.
Kidney international 20101001
-
Short- and mid-term intravascular ultrasound analysis of the new zotarolimus-eluting stent with durable polymer – results from the RESOLUTE trial –.
Circulation journal : official journal of the Japanese Circulation Society 20101001
-
Biological agents in kidney transplantation: belatacept is entering the field.
Expert opinion on biological therapy 20101001
-
Angiographic, IVUS and OCT evaluation of the long-term impact of coronary disease severity at the site of overlapping drug-eluting and bare metal stents: a substudy of the ODESSA trial.
Heart (British Cardiac Society) 20101001
-
Effect of rapamycin, an mTOR inhibitor, on radiation sensitivity of lung cancer cells having different p53 gene status.
International journal of oncology 20101001
-
Use of sirolimus in liver transplant recipients with renal insufficiency: a systematic review and meta-analysis.
Hepatology (Baltimore, Md.) 20101001
-
Autophagy-induced regression of hyaloid vessels in early ocular development.
Autophagy 20101001
-
Late vascular responses from 2 to 4 years after implantation of sirolimus-eluting stents: serial observations by intracoronary optical coherence tomography.
Circulation. Cardiovascular interventions 20101001
-
Temsirolimus: In relapsed and/or refractory mantle cell lymphoma.
Drugs 20101001
-
De novo therapy with everolimus, low-dose ciclosporine A, basiliximab and steroid elimination in pediatric kidney transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101001
-
Loss of nephrin expression in glomeruli of kidney-transplanted patients under m-TOR inhibitor therapy.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101001
-
18F-FLT PET as a surrogate marker of drug efficacy during mTOR inhibition by everolimus in a preclinical cisplatin-resistant ovarian tumor model.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20101001
-
Intravascular ultrasound findings of stent fractures in patients with Sirolimus- and Paclitaxel-eluting stents.
The American journal of cardiology 20101001
-
Monitoring molecular-specific pharmacodynamics of rapamycin in vivo with inducible Gal4->Fluc transgenic reporter mice.
Molecular cancer therapeutics 20101001
-
Phase II trial of gefitinib and everolimus in advanced non-small cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20101001
-
Everolimus: a proliferation signal inhibitor with clinical applications in organ transplantation, oncology, and cardiology.
Pharmacotherapy 20101001
-
Rapamycin regulates stearoyl CoA desaturase 1 expression in breast cancer.
Molecular cancer therapeutics 20101001
-
Effect of sirolimus on renal injury induced by bile duct ligation in rats.
Acta cirurgica brasileira 20101001
-
Diaphragm rupture in a liver transplant patient receiving chronic immunosuppressive therapy with sirolimus.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20101001
-
Rapamycin as an alternative to surgical treatment of subependymal giant cell astrocytomas in a patient with tuberous sclerosis complex.
Journal of neurosurgery. Pediatrics 20101001
-
Dramatic improvement in pulmonary hypertension with rapamycin.
Chest 20101001
-
Does early (CNI) conversion lead to eternal (renal) salvation?
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101001
-
Rapid adoption of drug-eluting stents: clinical practices and outcomes from the early drug-eluting stent era.
American heart journal 20101001
-
Serial angiographic findings and prognosis of stent fracture site without early restenosis after sirolimus-eluting stent implantation.
American heart journal 20101001
-
Oct1 is required for mTOR-induced G1 cell cycle arrest via the control of p27(Kip1) expression.
Cell cycle (Georgetown, Tex.) 20101001
-
Current status of the Xience V® everolimus-eluting coronary stent system.
Expert review of cardiovascular therapy 20101001
-
Paclitaxel-coated balloons - Survey of preclinical data.
Minerva cardioangiologica 20101001
-
Two-year clinical outcomes after large coronary stent (4.0 mm) placement: comparison of bare-metal stent versus drug-eluting stent.
Clinical cardiology 20101001
-
Improved late clinical safety with zotarolimus-eluting stents compared with paclitaxel-eluting stents in patients with de novo coronary lesions: 3-year follow-up from the ENDEAVOR IV (Randomized Comparison of Zotarolimus- and Paclitaxel-Eluting Stents in Patients With Coronary Artery Disease) trial.
JACC. Cardiovascular interventions 20101001
-
The unrestricted use of sirolimus- and paclitaxel-eluting stents results in better clinical outcomes during 6-year follow-up than bare-metal stents: an analysis of the RESEARCH (Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital) and T-SEARCH (Taxus-Stent Evaluated At Rotterdam Cardiology Hospital) registries.
JACC. Cardiovascular interventions 20101001
-
Different patterns of vascular response between patients with or without diabetes mellitus after drug-eluting stent implantation: optical coherence tomographic analysis.
JACC. Cardiovascular interventions 20101001
-
Late conversion to mammalian target of rapamycin inhibitor/proliferation signal inhibitors in kidney transplant patients: clinical experience in the last 5 years.
Transplantation proceedings 20101001
-
Proliferation signal inhibitors in heart transplantation: a 5-year experience.
Transplantation proceedings 20101001
-
Temporal trends in the use of proliferation signal inhibitors in maintenance heart transplantation: a Spanish multicenter study.
Transplantation proceedings 20101001
-
Evaluation of a fully automated method for the determination of sirolimus.
Transplantation proceedings 20101001
-
Comparative analysis of adverse events requiring suspension of mTOR inhibitors: everolimus versus sirolimus.
Transplantation proceedings 20101001
-
Pneumonitis associated with mammalian target of rapamycin inhibitors in renal transplant recipients: a single-center experience.
Transplantation proceedings 20101001
-
Clinical outcomes and cost-utility after sirolimus-eluting versus bare metal stent implantation.
Chinese medical journal 20101001
-
Androgen receptor-mTOR crosstalk is regulated by testosterone availability: implication for prostate cancer cell survival.
Anticancer research 20101001
-
Antiproliferative effects of rapamycin and celecoxib in angiosarcoma cell lines.
Anticancer research 20101001
-
Everolimus for the second-line treatment of advanced and/or metastatic renal cell cancer: a critique of the submission from Novartis.
Health technology assessment (Winchester, England) 20101001
-
Modulation of ghrelin O-acyltransferase expression in pancreatic islets.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20101001
-
Comment on 'Infantile spasms: a U.S. consensus report'.
Epilepsia 20101001
-
Rapamycin protects heart from ischemia/reperfusion injury independent of autophagy by activating PI3 kinase-Akt pathway and mitochondria K(ATP) channel.
Die Pharmazie 20101001
-
[Efficacy comparison of primary percutaneous coronary intervention with biodegradable polymer- and durable polymer-based sirolimus-eluting stents for patients with acute myocardial infarction].
Zhonghua xin xue guan bing za zhi 20101001
-
Combination therapy in patients with metastatic renal cell carcinoma.
Clinical advances in hematology & oncology : H&O 20101001
-
Recent advances in the discovery of small molecule mTOR inhibitors.
Future medicinal chemistry 20101001
-
Prolonging hormone sensitivity in prostate cancer xenografts through dual inhibition of AR and mTOR.
British journal of cancer 20100928
-
Improvement in renal function after late conversion to sirolimus-based immunosuppression in composite tissue allotransplantation.
Transplantation 20100927
-
Clinical outcomes after implantation of small diameter (=2.5Â mm) sirolimus- versus paclitaxel-eluting stents.
International journal of cardiology 20100924
-
Dual-color click beetle luciferase heteroprotein fragment complementation assays.
Chemistry & biology 20100924
-
[Everolimus-associated pneumonitis in adult liver transplant recipient].
Medicina clinica 20100918
-
Phase 3 trial of everolimus for metastatic renal cell carcinoma : final results and analysis of prognostic factors.
Cancer 20100915
-
Visceral Kaposi's sarcoma remission after intestinal transplant. First case report and systematic literature review.
Transplantation 20100915
-
Effect of coronary target lesion revascularization on late cardiac events after insertion of sirolimus-eluting or bare metal stents.
The American journal of cardiology 20100915
-
Safety and efficacy of the combination of erlotinib and sirolimus for the treatment of metastatic renal cell carcinoma after failure of sunitinib or sorafenib.
British journal of cancer 20100907
-
Treatment of prostate and breast tumors employing mono- and bi-specific antisense oligonucleotides targeting apoptosis inhibitory proteins clusterin and bcl-2.
Medical oncology (Northwood, London, England) 20100901
-
Spontaneous pyopneumothorax in patients treated with mTOR inhibitors for subpleural pulmonary metastases.
Medical oncology (Northwood, London, England) 20100901
-
Targeted agents in metastatic Xp11 translocation/TFE3 gene fusion renal cell carcinoma (RCC): a report from the Juvenile RCC Network.
Annals of oncology : official journal of the European Society for Medical Oncology 20100901
-
Combination of clopidogrel and everolimus dramatically reduced the development of transplant arteriosclerosis in murine aortic allografts.
Transplant international : official journal of the European Society for Organ Transplantation 20100901
-
Phosphorylated mTOR expression is associated with poor prognosis for patients with esophageal squamous cell carcinoma.
Annals of surgical oncology 20100901
-
Compensatory activation of Akt in response to mTOR and Raf inhibitors - a rationale for dual-targeted therapy approaches in neuroendocrine tumor disease.
Cancer letters 20100901
-
Rapamycin-induced phosphaturia.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100901
-
Cell-type- and cell-cycle-specific anti-mitogenesis by cicaprost.
Prostaglandins & other lipid mediators 20100901
-
Severe sirolimus-induced acute hepatitis in a renal transplant recipient.
Transplant international : official journal of the European Society for Organ Transplantation 20100901
-
Identification of p27/KIP1 expression level as a candidate biomarker of response to rapalogs therapy in human cancer.
Journal of molecular medicine (Berlin, Germany) 20100901
-
Everolimus as a new potential antiproliferative agent in aggressive human bronchial carcinoids.
Endocrine-related cancer 20100901
-
Rapamycin induces growth retardation by disrupting angiogenesis in the growth plate.
Kidney international 20100901
-
Bevacizumab and everolimus in the treatment of patients with metastatic melanoma: a phase 2 trial of the Sarah Cannon Oncology Research Consortium.
Cancer 20100901
-
Antiproliferation of cardamonin is involved in mTOR on aortic smooth muscle cells in high fructose-induced insulin resistance rats.
European journal of pharmacology 20100901
-
Coronary microvascular endothelial function deteriorates late (12 months) after sirolimus-eluting stent implantation.
Journal of cardiology 20100901
-
Choice of stenting strategy in true coronary artery bifurcation lesions.
Coronary artery disease 20100901
-
Cutaneous T-cell lymphoma cells are sensitive to rapamycin.
Experimental dermatology 20100901
-
Pilot study: rapamycin in advanced hepatocellular carcinoma.
Alimentary pharmacology & therapeutics 20100901
-
Human chorionic gonadotropin stimulates theca-interstitial cell proliferation and cell cycle regulatory proteins by a cAMP-dependent activation of AKT/mTORC1 signaling pathway.
Molecular endocrinology (Baltimore, Md.) 20100901
-
Everolimus: efficacy and safety in cardiac transplantation.
Expert opinion on drug safety 20100901
-
Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens.
EMBO molecular medicine 20100901
-
Autophagy induction with RAD001 enhances chemosensitivity and radiosensitivity through Met inhibition in papillary thyroid cancer.
Molecular cancer research : MCR 20100901
-
Rapamycin and thalidomide treatment of a patient with refractory metastatic gastroesophageal adenocarcinoma: a case report.
The oncologist 20100901
-
[Second line AUO study AB35/09 of metastasized urothelial cell carcinoma].
Der Urologe. Ausg. A 20100901
-
Can autophagy promote longevity?
Nature cell biology 20100901
-
Updates of mTOR inhibitors.
Anti-cancer agents in medicinal chemistry 20100901
-
Vulnerable disease may induce neointimal coverage after sirolimus-eluting stent implantation.
American heart journal 20100901
-
Everolimus-eluting stents: insights from the SPIRIT IV and COMPARE trials.
Expert review of cardiovascular therapy 20100901
-
Percutaneous coronary intervention for small-vessel coronary disease: highlight on the everolimus-eluting stent.
Expert review of cardiovascular therapy 20100901
-
Bone disease in renal transplantation and pleotropic effects of vitamin D therapy.
Transplantation proceedings 20100901
-
Sirolimus-induced isometric tubular vacuolization: a new sirolimus histopathologic manifestation.
Transplantation proceedings 20100901
-
Timing of conversion to mammalian target of rapamycin inhibitors is crucial in liver transplant recipients with impaired renal function at transplantation.
Transplantation proceedings 20100901
-
Sirolimus in liver transplant recipients: a large single-center experience.
Transplantation proceedings 20100901
-
Influence of immunosuppressive drugs on the development of CD4(+)CD25(high) Foxp3(+) T cells in liver transplant recipients.
Transplantation proceedings 20100901
-
Sirolimus is associated with impaired hematopoiesis in heart transplant patients? A retrospective analysis.
Transplantation proceedings 20100901
-
American Society of Clinical Oncology 2010: report of selected studies from the CNS tumors section.
Expert review of anticancer therapy 20100901
-
Comparison of sirolimus- and paclitaxel-eluting stents in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction: a meta-analysis of randomized trials.
Clinical cardiology 20100901
-
mTOR pathway inhibitors in cancer therapy: moving past rapamycin.
Pharmacogenomics 20100901
-
Rapamycin and MPA, but not CsA, impair human NK cell cytotoxicity due to differential effects on NK cell phenotype.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100901
-
Comparison of everolimus-eluting and paclitaxel-eluting coronary stents in patients with two treated vessels: 2-year results from the SPIRIT III randomised trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100901
-
Three-year results of clinical follow-up after a bioresorbable everolimus-eluting scaffold in patients with de novo coronary artery disease: the ABSORB trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100901
-
Impact of arterial injury on neointimal hyperplasia after implantation of drug-eluting stents in coronary arteries: an intravascular ultrasound study.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100901
-
Vascular response to a third generation everolimus-eluting stent.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100901
-
Differential expression of mTOR signalling components in drug resistance in ovarian cancer.
Anticancer research 20100901
-
Ridaforolimus.
Drugs in R&D 20100901
-
Inflammation inhibitory effects of sirolimus and paclitaxel-eluting stents on interleukin-1β-induced coronary artery in-stent restenosis in pigs.
Chinese medical journal 20100901
-
[Inhibition of cell growth by rapamycin through targeting mammalian target of rapamycin signaling pathway in nasopharyngeal carcinoma].
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20100901
-
Antihyperalgesic and antiallodynic effect of sirolimus in neuropathic pain and the role of cytokines in this effect.
Neuroscience letters 20100830
-
Murine cytomegalovirus infection leads to increased levels of transplant arteriosclerosis in a murine aortic allograft model.
Transplantation 20100827
-
Sirolimus and kidney growth in autosomal dominant polycystic kidney disease.
The New England journal of medicine 20100826
-
Everolimus in patients with autosomal dominant polycystic kidney disease.
The New England journal of medicine 20100826
-
mTOR inhibitors in polycystic kidney disease.
The New England journal of medicine 20100826
-
Rapamycin activates autophagy and improves myelination in explant cultures from neuropathic mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20100825
-
Integrated preclinical and clinical development of mTOR inhibitors in pancreatic cancer.
British journal of cancer 20100824
-
Dual inhibition of EGFR and mTOR pathways in small cell lung cancer.
British journal of cancer 20100824
-
Regulation of the autophagy protein LC3 by phosphorylation.
The Journal of cell biology 20100823
-
Resistance to mammalian target of rapamycin inhibitor therapy in perivascular epithelioid cell tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100820
-
Neuroscience. A glutamate pathway to faster-acting antidepressants?
Science (New York, N.Y.) 20100820
-
mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists.
Science (New York, N.Y.) 20100820
-
Correlation of tissue drug concentrations with in vivo magnetic resonance images of polymer drug depot around arteriovenous graft.
Journal of controlled release : official journal of the Controlled Release Society 20100817
-
Early and late effects of the immunosuppressants rapamycin and mycophenolate mofetil on UV carcinogenesis.
International journal of cancer 20100815
-
Phase 1 and pharmacokinetic study of everolimus, a mammalian target of rapamycin inhibitor, in combination with docetaxel for recurrent/refractory nonsmall cell lung cancer.
Cancer 20100815
-
Intermittent antibody-based combination therapy removes alloantibodies and achieves indefinite heart transplant survival in presensitized recipients.
Transplantation 20100815
-
Cutting edge: Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses.
Journal of immunology (Baltimore, Md. : 1950) 20100815
-
Manipulating signal delivery - plasma-membrane ERK activation in aPKC-dependent migration.
Journal of cell science 20100815
-
Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer.
Cancer research 20100815
-
Comparison of everolimus- versus paclitaxel-eluting stents implanted in patients with diabetes mellitus as evaluated by three-dimensional intravascular ultrasound analysis.
The American journal of cardiology 20100815
-
Three-year outcomes following sirolimus- versus paclitaxel-eluting stent implantation in an unselected population with coronary artery disease (from the REWARDS Registry).
The American journal of cardiology 20100815
-
A novel clinically relevant approach to tip the balance toward regulation in stringent transplant model.
Transplantation 20100815
-
Revisiting the antagonistic pleiotropy theory of aging: TOR-driven program and quasi-program.
Cell cycle (Georgetown, Tex.) 20100815
-
Altered VEGF mRNA stability following treatments with immunosuppressive agents: implications for cancer development.
The Journal of biological chemistry 20100813
-
A novel Ca2+/calmodulin antagonist HBC inhibits angiogenesis and down-regulates hypoxia-inducible factor.
The Journal of biological chemistry 20100813
-
MLK3 is critical for breast cancer cell migration and promotes a malignant phenotype in mammary epithelial cells.
Oncogene 20100805
-
Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus.
The Journal of clinical investigation 20100802
-
PIK3CA and KRAS mutations predict for response to everolimus therapy: now that's RAD001.
The Journal of clinical investigation 20100802
-
The activity of mTOR inhibitor RAD001 (everolimus) in nasopharyngeal carcinoma and cisplatin-resistant cell lines.
Investigational new drugs 20100801
-
Large-scale expansion of pluripotent human embryonic stem cells in stirred-suspension bioreactors.
Tissue engineering. Part C, Methods 20100801
-
Sirolimus attenuates reduced-size liver ischemia-reperfusion injury but impairs liver regeneration in rats.
Digestive diseases and sciences 20100801
-
Enzastaurin (LY317615), a protein kinase C beta selective inhibitor, enhances antiangiogenic effect of radiation.
International journal of radiation oncology, biology, physics 20100801
-
Effect of everolimus on skin cancers in calcineurin inhihitor-treated heart transplant recipients.
Transplant international : official journal of the European Society for Organ Transplantation 20100801
-
Fatal diffuse alveolar hemorrhage associated with sirolimus after allogeneic hematopoietic cell transplantation.
Bone marrow transplantation 20100801
-
Sirolimus for treatment of steroid-refractory acute graft-versus-host disease.
Bone marrow transplantation 20100801
-
Sirolimus in renal transplant recipients with tuberous sclerosis complex: clinical effectiveness and implications for innate immunity.
Transplant international : official journal of the European Society for Organ Transplantation 20100801
-
Combination of tipifarnib and rapamycin synergistically inhibits the growth of leukemia cells and overcomes resistance to tipifarnib via alteration of cellular signaling pathways.
Leukemia research 20100801
-
Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells.
Breast cancer research and treatment 20100801
-
Noninfectious pneumonitis after everolimus therapy for advanced renal cell carcinoma.
American journal of respiratory and critical care medicine 20100801
-
Neoadjuvant temsirolimus effectiveness in downstaging advanced non-clear cell renal cell carcinoma.
European urology 20100801
-
IGFBP-2 expression in MCF-7 cells is regulated by the PI3K/AKT/mTOR pathway through Sp1-induced increase in transcription.
Growth factors (Chur, Switzerland) 20100801
-
Surface characterization of poly(lactic acid)/everolimus and poly(ethylene vinyl alcohol)/everolimus stents.
Drug delivery 20100801
-
Inhibition of mTORC1 by RAD001 (everolimus) potentiates the effects of 1,25-dihydroxyvitamin D(3) to induce growth arrest and differentiation of AML cells in vitro and in vivo.
Experimental hematology 20100801
-
Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice.
Gastroenterology 20100801
-
A spectrophotometric assay for routine measurement of mammalian target of rapamycin activity in cell lysates.
Analytical biochemistry 20100801
-
A Phase 1 clinical study of temsirolimus (CCI-779) in Japanese patients with advanced solid tumors.
Japanese journal of clinical oncology 20100801
-
Drug-eluting stents ameliorate pulmonary vein stenotic changes in pigs in vivo.
Pediatric cardiology 20100801
-
Sirolimus has a potential to influent viral recurrence in HCV positive liver transplant candidates.
International immunopharmacology 20100801
-
Pulmonary alveolar proteinosis in a kidney transplant: a rare complication of sirolimus.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100801
-
Endocrine control of oleic acid and glucose metabolism in rainbow trout (Oncorhynchus mykiss) muscle cells in culture.
American journal of physiology. Regulatory, integrative and comparative physiology 20100801
-
Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis.
Arthritis and rheumatism 20100801
-
Treatment with rapamycin prevents fibrosis in tight-skin and bleomycin-induced mouse models of systemic sclerosis.
Arthritis and rheumatism 20100801
-
Increased serum vWF and sVCAM-1 levels are associated with late or very late angiographic stent thrombosis after sirolimus-eluting stent implantation.
Coronary artery disease 20100801
-
Intravascular ultrasound criteria for determination of optimal longitudinal positioning of sirolimus-eluting stents.
Circulation journal : official journal of the Japanese Circulation Society 20100801
-
Liquid chromatography-tandem mass spectrometry outperforms fluorescence polarization immunoassay in monitoring everolimus therapy in renal transplantation.
Therapeutic drug monitoring 20100801
-
Effective targeting of STAT5-mediated survival in myeloproliferative neoplasms using ABT-737 combined with rapamycin.
Leukemia 20100801
-
Effects of sirolimus alone or in combination with cyclosporine A on renal ischemia/reperfusion injury.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20100801
-
Protein denaturation and protein:drugs interactions from intrinsic protein fluorescence measurements at the nanolitre scale.
Protein science : a publication of the Protein Society 20100801
-
Inhibition of glycogen biosynthesis via mTORC1 suppression as an adjunct therapy for Pompe disease.
Molecular genetics and metabolism 20100801
-
Beclin 1 self-association is independent of autophagy induction by amino acid deprivation and rapamycin treatment.
Journal of cellular biochemistry 20100801
-
Comparison of sirolimus-eluting and bare metal stent for treatment of patients with total coronary occlusions: results of the GISSOC II-GISE multicentre randomized trial.
European heart journal 20100801
-
New inhibitors of the mammalian target of rapamycin signaling pathway for cancer.
Expert opinion on investigational drugs 20100801
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Sirolimus and mycophenolate as combination prophylaxis in corneal transplant recipients at high rejection risk.
American journal of ophthalmology 20100801
-
TSC1/2 tumour suppressor complex maintains Drosophila germline stem cells by preventing differentiation.
Development (Cambridge, England) 20100801
-
The application of the National Institute of Clinical Excellence guidelines for treatment of metastatic renal cell carcinoma in the United Kingdom: friend or foe?
BJU international 20100801
-
Biosynthesis of rapamycin and its regulation: past achievements and recent progress.
The Journal of antibiotics 20100801
-
Differential proteome and phosphoproteome signatures in human T-lymphoblast cells induced by sirolimus.
Cell proliferation 20100801
-
In vitro effects of everolimus and intravenous immunoglobulin on cell proliferation and apoptosis induction in the mixed lymphocyte reaction.
Transplant immunology 20100801
-
Do drug elution components increase the risk of fracture of sirolimus-eluting stents?
Coronary artery disease 20100801
-
Conversion to sirolimus in renal transplant recipients: a single-center experience.
Artificial organs 20100801
-
Everolimus in the treatment of renal cell carcinoma and neuroendocrine tumors.
Advances in therapy 20100801
-
Rapamycin-conditioned donor dendritic cells differentiate CD4CD25Foxp3 T cells in vitro with TGF-beta1 for islet transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100801
-
Incidence and risk factors of late target lesion revascularization after sirolimus-eluting stent implantation (3-year follow-up of the j-Cypher Registry).
The American journal of cardiology 20100801
-
Comparison of sirolimus-eluting stents with paclitaxel-eluting stents in saphenous vein graft intervention (from a multicenter Southern California Registry).
The American journal of cardiology 20100801
-
The combination of multiple receptor tyrosine kinase inhibitor and mammalian target of rapamycin inhibitor overcomes erlotinib resistance in lung cancer cell lines through c-Met inhibition.
Molecular cancer research : MCR 20100801
-
Progeria syndromes and ageing: what is the connection?
Nature reviews. Molecular cell biology 20100801
-
Islet transplantation in type 1 diabetics using an immunosuppressive protocol based on the anti-LFA-1 antibody efalizumab.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100801
-
Off-label prescribing: a matter of trust.
Nature reviews. Nephrology 20100801
-
Elevated high sensitive C-reactive protein and apelin levels after percutaneous coronary intervention and drug-eluting stent implantation.
Journal of Zhejiang University. Science. B 20100801
-
Very late thrombosis after subintimal sirolimus-eluting stent implantation during percutaneous coronary intervention for chronic total occlusion.
The Journal of invasive cardiology 20100801
-
Primary use of sirolimus-eluting stents in the infrapopliteal arteries.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20100801
-
Commentary: infrapopliteal angioplasty with drug-eluting stents: from heart to toe.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20100801
-
Xenohormetic, hormetic and cytostatic selective forces driving longevity at the ecosystemic level.
Aging 20100801
-
How does the mammalian target of rapamycin (mTOR) influence CD8 T cell differentiation?
Cell cycle (Georgetown, Tex.) 20100801
-
Different patterns of BK and JC polyomavirus reactivation following renal transplantation.
Journal of clinical pathology 20100801
-
Targeted therapy at the end of life for patients with lung cancer.
Journal of palliative medicine 20100801
-
New drug-eluting stents: an overview on biodegradable and polymer-free next-generation stent systems.
Circulation. Cardiovascular interventions 20100801
-
3-Dimensional optical coherence tomography assessment of jailed side branches by bioresorbable vascular scaffolds: a proposal for classification.
JACC. Cardiovascular interventions 20100801
-
Effect of oral sirolimus therapy on inflammatory biomarkers following coronary stenting.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20100801
-
Arnold Lester Demain: a good friend, an outstanding scientist and a valuable professor.
The Journal of antibiotics 20100801
-
Everolimus in renal cell carcinoma.
Drugs of today (Barcelona, Spain : 1998) 20100801
-
Short and long term comparison (24 months) of an alternative sirolimus-coated stent with bioabsorbable polymer and a bare metal stent of similar design in chronic coronary occlusions: the CORACTO trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100801
-
Intravascular ultrasound, angioscopic and histopathological characterisation of heterogeneous patterns of restenosis after sirolimus-eluting stent implantation: insights into potential 'thromborestenosis' phenomenon.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100801
-
A quantitative coronary angiography-matched comparison between a prospective randomised multicentre cutting balloon angioplasty and bare metal stent trial (REDUCE III) and the Rapamycin-Eluting Stent Evaluation At Rotterdam Cardiology Hospital (RESEARCH) study.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100801
-
The combination of sirolimus and rosiglitazone produces a renoprotective effect on diabetic kidney disease in rats.
Life sciences 20100731
-
Rapamycin promotes beta-amyloid production via ADAM-10 inhibition.
Biochemical and biophysical research communications 20100730
-
Modulation of high-voltage activated Ca(2+) channels by membrane phosphatidylinositol 4,5-bisphosphate.
Neuron 20100729
-
Renal function, efficacy, and safety of sirolimus and mycophenolate mofetil after short-term calcineurin inhibitor-based quadruple therapy in de novo renal transplant patients: one-year analysis of a randomized multicenter trial.
Transplantation 20100727
-
Effect of sirolimus on calcineurin inhibitor-induced nephrotoxicity using renal expression of KLOTHO, an antiaging gene.
Transplantation 20100727
-
The TOR complex 1 is distributed in endosomes and in retrograde vesicles that form from the vacuole membrane and plays an important role in the vacuole import and degradation pathway.
The Journal of biological chemistry 20100723
-
Identification of Pep4p as the protease responsible for formation of the SAGA-related SLIK protein complex.
The Journal of biological chemistry 20100723
-
[Chronic renal failure is associated with worse outcome after implantation of sirolimus eluting stent].
Medicina clinica 20100717
-
Selective induction of catalase-mediated autophagy by dihydrocapsaicin in lung cell lines.
Free radical biology & medicine 20100715
-
Enteric-coated mycophenolate sodium versus mycophenolate mofetil maintenance immunosuppression: outcomes analysis of the United Network for Organ Sharing/Organ Procurement and Transplantation Network database.
Transplantation 20100715
-
R1507, a fully human monoclonal antibody targeting IGF-1R, is effective alone and in combination with rapamycin in inhibiting growth of osteosarcoma xenografts.
Pediatric blood & cancer 20100715
-
Optimal everolimus concentration is associated with risk reduction for acute rejection in de novo renal transplant recipients.
Transplantation 20100715
-
mTORC1 signaling in Parkinson's disease and L-DOPA-induced dyskinesia: A sensitized matter.
Cell cycle (Georgetown, Tex.) 20100715
-
The efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 compared with rapamycin in renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20100715
-
Comparison of zotarolimus-eluting and everolimus-eluting coronary stents.
The New England journal of medicine 20100708
-
Sirolimus-eluting stent versus balloon angioplasty for sirolimus-eluting stent restenosis: Insights from the j-Cypher Registry.
Circulation 20100706
-
Comparisons of baseline demographics, clinical presentation, and long-term outcome among patients with early, late, and very late stent thrombosis of sirolimus-eluting stents: Observations from the Registry of Stent Thrombosis for Review and Reevaluation (RESTART).
Circulation 20100706
-
Sirolimus therapy for fibromatosis and multifocal renal cell carcinoma in a child with tuberous sclerosis complex.
Pediatric blood & cancer 20100701
-
Effect of combination treatment of rapamycin and isoflavones on mTOR pathway in human glioblastoma (U87) cells.
Neurochemical research 20100701
-
Antiangiogenic effects and transcriptional regulation of pigment epithelium-derived factor in diabetic retinopathy.
Microvascular research 20100701
-
Inhibition of MEK/ERK signaling induces apoptosis of acute myelogenous leukemia cells via inhibition of eukaryotic initiation factor 4E-binding protein 1 and down-regulation of Mcl-1.
Apoptosis : an international journal on programmed cell death 20100701
-
Inhibition of mTORC1 signaling reduces tumor growth but does not prevent cancer progression in a mouse model of thyroid cancer.
Carcinogenesis 20100701
-
Four-year clinical outcome of sirolimus- and paclitaxel-eluting stents compared to bare-metal stents for the percutaneous treatment of stable coronary artery disease.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701
-
In vitro and in vivo changes to PLGA/sirolimus coating on drug eluting stents.
Biomaterials 20100701
-
MTOR downregulates iodide uptake in thyrocytes.
The Journal of endocrinology 20100701
-
Gingival overgrowth in cyclosporine, tacrolimus, or sirolimus-based immunosuppressive regimens and the single nucleotide IL-6 (-174 G/C) gene polymorphism.
Archives of oral biology 20100701
-
Regulation of the creatine transporter by AMP-activated protein kinase in kidney epithelial cells.
American journal of physiology. Renal physiology 20100701
-
New developments in targeted therapy for soft tissue sarcoma.
Current oncology reports 20100701
-
Sirolimus and everolimus reduce albumin endocytosis in proximal tubule cells via an angiotensin II-dependent pathway.
Transplant immunology 20100701
-
New drugs in neuroendocrine tumors: rising of new therapeutic philosophies?
Current opinion in oncology 20100701
-
Gene expression profiling of response to mTOR inhibitor everolimus in pre-operatively treated post-menopausal women with oestrogen receptor-positive breast cancer.
Breast cancer research and treatment 20100701
-
cAMP-dependent activation of mammalian target of rapamycin (mTOR) in thyroid cells. Implication in mitogenesis and activation of CDK4.
Molecular endocrinology (Baltimore, Md.) 20100701
-
Complete resolution of oral Kaposi's sarcoma achieved by changing immunosuppression: a case report.
Annals of the Royal College of Surgeons of England 20100701
-
Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor-positive human breast cancer.
The Journal of clinical investigation 20100701
-
Visualization of embryonic lymphangiogenesis advances the use of the zebrafish model for research in cancer and lymphatic pathologies.
Developmental dynamics : an official publication of the American Association of Anatomists 20100701
-
Outcomes after differential use of drug-eluting stents in diabetic patients: 1-year results from the DES.DE (Drug-Eluting Stent.DEutschland) registry.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701
-
Which DES for diabetics? Round 1: A draw. Round 2: Everolimus leading?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701
-
An everolimus-eluting stent versus a paclitaxel-eluting stent in small vessel coronary artery disease: a pooled analysis from the SPIRIT II and SPIRIT III trials.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701
-
Another small step for small vessels.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701
-
[Sirolimus-eluting stent in the prevention of restenosis in small coronary arteries].
La Tunisie medicale 20100701
-
Development and performance of the zotarolimus-eluting Endeavor coronary stent.
Expert review of medical devices 20100701
-
Effectiveness and safety of drug-eluting stents in a cardiology clinic in Curitiba, PR, Brazil.
Arquivos brasileiros de cardiologia 20100701
-
Recent advances in the development of selective, ATP-competitive inhibitors of mTOR.
Current opinion in drug discovery & development 20100701
-
Efficacy and safety of rapamycin as compared to paclitaxel-eluting stents: a meta-analysis.
The Journal of invasive cardiology 20100701
-
Long-term clinical outcome of sirolimus-eluting stent implantation in metabolic syndrome and diabetes.
The Journal of invasive cardiology 20100701
-
Three-year outcome of sirolimus-eluting versus bare-metal stents for the treatment of ST-segment elevation myocardial infarction (from the MISSION! Intervention Study).
The American journal of cardiology 20100701
-
SPIRIT III JAPAN versus SPIRIT III USA: a comparative intravascular ultrasound analysis of the everolimus-eluting stent.
The American journal of cardiology 20100701
-
Therapeutic approaches to epileptogenesis--hope on the horizon.
Epilepsia 20100701
-
Modeling new therapies for infantile spasms.
Epilepsia 20100701
-
Clinical recommendations for the use of everolimus in heart transplantation.
Transplantation reviews (Orlando, Fla.) 20100701
-
Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes.
Aging 20100701
-
[Current impact of natural products in the discovery of anticancer drugs].
Annales pharmaceutiques francaises 20100701
-
Influence of immunosuppression on alloresponse, inflammation and contractile function of graft after intestinal transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100701
-
Therapeutic mTOR inhibition in autosomal dominant polycystic kidney disease: What is the appropriate serum level?
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100701
-
Topical rapamycin: a novel approach to facial angiofibromas in tuberous sclerosis.
Archives of dermatology 20100701
-
Specific coronary drug-eluting stents interfere with distal microvascular function after single stent implantation in pigs.
JACC. Cardiovascular interventions 20100701
-
[Subacute thrombosis of drug eluting stent immediately after off-pump coronary artery bypass grafting].
Kyobu geka. The Japanese journal of thoracic surgery 20100701
-
Temsirolimus: is improved survival the correct expression of drug activity?
The oncologist 20100701
-
Combination therapy of 5-fluorouracil with rapamycin for hormone receptor-negative human breast cancer.
Anticancer research 20100701
-
Rapamycin treatment suppresses epileptogenic activity in conditional Pten knockout mice.
Cell cycle (Georgetown, Tex.) 20100701
-
Thymoglobulin induction and sirolimus versus tacrolimus in kidney transplant recipients receiving mycophenolate mofetil and steroids.
Transplantation 20100627
-
Oxidative stress changes after stent implantation: a randomized comparative study of sirolimus-eluting and bare metal stents.
International journal of cardiology 20100625
-
Design of selective, ATP-competitive inhibitors of Akt.
Journal of medicinal chemistry 20100624
-
Mammalian target of rapamycin (mTOR) and S6 kinase down-regulate phospholipase D2 basal expression and function.
The Journal of biological chemistry 20100618
-
Randomized trial of paclitaxel- versus sirolimus-eluting stents for treatment of coronary restenosis in sirolimus-eluting stents: the ISAR-DESIRE 2 (Intracoronary Stenting and Angiographic Results: Drug Eluting Stents for In-Stent Restenosis 2) study.
Journal of the American College of Cardiology 20100615
-
Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks.
Circulation research 20100611
-
Structure of the human mTOR complex I and its implications for rapamycin inhibition.
Molecular cell 20100611
-
Chemically controlled protein assembly: techniques and applications.
Chemical reviews 20100609
-
2-year clinical and angiographic outcomes from a randomized trial of polymer-free dual drug-eluting stents versus polymer-based Cypher and Endeavor [corrected] drug-eluting stents.
Journal of the American College of Cardiology 20100608
-
Distinct phosphatase requirements and GATA factor responses to nitrogen catabolite repression and rapamycin treatment in Saccharomyces cerevisiae.
The Journal of biological chemistry 20100604
-
Mechanisms involved in the enhancement of mammalian target of rapamycin signalling and hypertrophy in skeletal muscle of myostatin-deficient mice.
FEBS letters 20100603
-
Feasibility of sequential use of sunitinib and temsirolimus in advanced renal cell carcinoma.
Medical oncology (Northwood, London, England) 20100601
-
Phase I, pharmacokinetic study of temsirolimus administered orally to patients with advanced cancer.
Investigational new drugs 20100601
-
Mammalian target of rapamycin (mTOR) is involved in the survival of cells mediated by chemokine receptor 7 through PI3K/Akt in metastatic squamous cell carcinoma of the head and neck.
The British journal of oral & maxillofacial surgery 20100601
-
Gonadal dysfunction and infertility in kidney transplant patients receiving sirolimus.
International urology and nephrology 20100601
-
A model of chronic lung allograft rejection in the rat.
The European respiratory journal 20100601
-
Rapamycin enhances chemotherapy-induced cytotoxicity by inhibiting the expressions of TS and ERK in gastric cancer cells.
International journal of cancer 20100601
-
Phase Ib study of weekly mammalian target of rapamycin inhibitor ridaforolimus (AP23573; MK-8669) with weekly paclitaxel.
Annals of oncology : official journal of the European Society for Medical Oncology 20100601
-
Sirolimus-associated acute interstitial nephritis in a renal allograft.
Transplant international : official journal of the European Society for Organ Transplantation 20100601
-
FAK mediates the activation of cardiac fibroblasts induced by mechanical stress through regulation of the mTOR complex.
Cardiovascular research 20100601
-
The role of mTOR signaling in controlling mammalian life span: what a fungicide teaches us about longevity.
The journals of gerontology. Series A, Biological sciences and medical sciences 20100601
-
Correlation between circulating endothelial progenitor cell function and allograft rejection in heart transplant patients.
Transplant international : official journal of the European Society for Organ Transplantation 20100601
-
Cyclosporine, tacrolimus and sirolimus retain their distinct toxicity profiles despite low doses in the Symphony study.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100601
-
Switch to a sirolimus-based immunosuppression in long-term renal transplant recipients: reduced rate of (pre-)malignancies and nonmelanoma skin cancer in a prospective, randomized, assessor-blinded, controlled clinical trial.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100601
-
Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1.
Cellular signalling 20100601
-
Long-term complication after LM bifurcation treatment.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601
-
Proximal protection in recanalization of totally occluded saphenous vein grafts in acute coronary syndrome.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601
-
Update on systemic therapies of metastatic renal cell carcinoma.
World journal of urology 20100601
-
Reversible severe synovitis associated with everolimus.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20100601
-
Central leptin treatment modulates brain glucosensing function and peripheral energy metabolism of rainbow trout.
Peptides 20100601
-
Substitution of corticosteroid with everolimus after lung transplantation: a pediatric case report.
Pharmacy world & science : PWS 20100601
-
Pharmacokinetic and pharmacodynamic interactions between the immunosuppressant sirolimus and the lipid-lowering drug ezetimibe in healthy volunteers.
Clinical pharmacology and therapeutics 20100601
-
PI3K/Akt and mTOR/p70S6K pathways mediate neuroprotectin D1-induced retinal pigment epithelial cell survival during oxidative stress-induced apoptosis.
Experimental eye research 20100601
-
Sirolimus-based calcineurin inhibitor withdrawal immunosuppressive regimen in kidney transplantation: a single center experience.
Clinical and experimental nephrology 20100601
-
Downregulation of Akt/mammalian target of rapamycin pathway in skeletal muscle is associated with increased REDD1 expression in response to chronic hypoxia.
American journal of physiology. Regulatory, integrative and comparative physiology 20100601
-
Chronic rapamycin treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose tissue.
Diabetes 20100601
-
Benefit of early conversion from CNI-based to everolimus-based immunosuppression in heart transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20100601
-
Rhabdomyolysis and acute kidney injury secondary to concomitant use of fluvastatin and rapamycin in a renal transplant recipient.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100601
-
EP1 prostanoid receptor coupling to G i/o up-regulates the expression of hypoxia-inducible factor-1 alpha through activation of a phosphoinositide-3 kinase signaling pathway.
Molecular pharmacology 20100601
-
The protein kinase CaSch9p is required for the cell growth, filamentation and virulence in the human fungal pathogen Candida albicans.
FEMS yeast research 20100601
-
A phase I study of weekly temsirolimus and topotecan in the treatment of advanced and/or recurrent gynecologic malignancies.
Gynecologic oncology 20100601
-
Sirolimus inhibits endogenous cholesterol synthesis induced by inflammatory stress in human vascular smooth muscle cells.
American journal of physiology. Heart and circulatory physiology 20100601
-
Luteinizing hormone stimulates mammalian target of rapamycin signaling in bovine luteal cells via pathways independent of AKT and mitogen-activated protein kinase: modulation of glycogen synthase kinase 3 and AMP-activated protein kinase.
Endocrinology 20100601
-
The fate of incomplete stent apposition with drug-eluting stents: an optical coherence tomography-based natural history study.
European heart journal 20100601
-
Late progression after sirolimus-eluting stent implantation for de novo lesions--comparison with bare metal stent implantation.
Circulation journal : official journal of the Japanese Circulation Society 20100601
-
Does tacrolimus, in comparison with sirolimus, increase mycophenolic acid exposure in kidney transplant recipients?
Clinical pharmacology and therapeutics 20100601
-
Mammalian target of rapamycin (mTOR) regulates cellular proliferation and tumor growth in urothelial carcinoma.
The American journal of pathology 20100601
-
Emergent toxicities associated with the use of mTOR inhibitors in patients with advanced renal carcinoma.
Anti-cancer drugs 20100601
-
Effects of vatalanib on tumor growth can be potentiated by mTOR blockade in vivo.
Cancer biology & therapy 20100601
-
Rapamycin joins the aging fray: maybe Ponce de Leon visited Rapa Nui, not Florida.
The journals of gerontology. Series A, Biological sciences and medical sciences 20100601
-
Randomized intervention studies in human polycystic kidney and liver disease.
Journal of the American Society of Nephrology : JASN 20100601
-
Use of pharmacogenetics to optimize immunosuppressive therapy.
Therapeutic drug monitoring 20100601
-
Development of a novel prohealing stent designed to deliver sirolimus from a biodegradable abluminal matrix.
Circulation. Cardiovascular interventions 20100601
-
Everolimus plus reduced-exposure CsA versus mycophenolic acid plus standard-exposure CsA in renal-transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100601
-
Treatment of metastatic renal cell carcinoma.
Nature reviews. Urology 20100601
-
[Treatment of adult patients with metastatic sarcoma: current shift in concepts].
Bulletin du cancer 20100601
-
Sirolimus therapy to halt the progression of ADPKD.
Journal of the American Society of Nephrology : JASN 20100601
-
Optic nerve tumor in tuberous sclerosis complex is not responsive to sirolimus.
Pediatric neurology 20100601
-
Twelve-month outcomes in patients with diabetes implanted with a zotarolimus-eluting stent: results from the E-Five Registry.
Heart (British Cardiac Society) 20100601
-
PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 20100601
-
Regulation of insulin-like growth factor-mammalian target of rapamycin signaling by microRNA in childhood adrenocortical tumors.
Cancer research 20100601
-
A pharmacodynamic study of rapamycin in men with intermediate- to high-risk localized prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 20100601
-
Rapamycin reduces intrahepatic alpha-1-antitrypsin mutant Z protein polymers and liver injury in a mouse model.
Experimental biology and medicine (Maywood, N.J.) 20100601
-
Rapamycin regulates Akt and ERK phosphorylation through mTORC1 and mTORC2 signaling pathways.
Molecular carcinogenesis 20100601
-
Five-year long-term clinical follow-up of the XIENCE V everolimus eluting coronary stent system in the treatment of patients with de novo coronary artery lesions: the SPIRIT FIRST trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601
-
Long-term follow-up of the First In Man experience with everolimus-eluting stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601
-
Percutaneous UPLM revascularisation: the time has come.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601
-
Procedure-related myonecrosis after bare and drug-eluting stent implantation.
Asian cardiovascular & thoracic annals 20100601
-
Current progress in pharmacogenetics and individualized immunosuppressive drug dosing in organ transplantation.
Current opinion in molecular therapeutics 20100601
-
The TOR pathway modulates the structure of cell walls in Arabidopsis.
The Plant cell 20100601
-
Rapamycin can inhibit the development of Chlamydia pneumoniae, which might partly contribute to the prevention of in-stent restenosis.
Cardiovascular drugs and therapy 20100601
-
[mTOR inhibitors].
Nihon rinsho. Japanese journal of clinical medicine 20100601
-
The importance of skin cancer prevention in organ transplant patients an editorial to paper by Salgo: 'switch to sirolimus in long-term renal transplant recipients: reduced premalignancies and nonmelanoma skin cancer in a controlled, prospective, randomized, blinded study'.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100601
-
Clinical and angiographic outcomes of drug-eluting stents in patients with large vessel and single coronary artery lesion.
Clinical cardiology 20100601
-
A randomised comparison of novolimus-eluting and zotarolimus-eluting coronary stents: 9-month follow-up results of the EXCELLA II study.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100601
-
The twelve-month outcomes of a biolimus eluting stent with a biodegradable polymer compared with a sirolimus eluting stent with a durable polymer.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100601
-
Coronary angioscopic findings eight months after sirolimus-eluting stent implantation: a comparison between ST-elevation myocardial infarction and stable angina pectoris.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100601
-
Risk of diarrhoea in a long-term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the UGT1A8 2 variant allele.
British journal of clinical pharmacology 20100601
-
Targeting multiple angiogenic pathways for the treatment of neuroblastoma.
Journal of pediatric surgery 20100601
-
Comparison of the safety and efficacy of cyclosporine minimization versus cyclosporine elimination in de novo renal allograft patients receiving sirolimus.
Transplantation proceedings 20100601
-
Rapamycin promotes the expansion of CD4(+) Foxp3(+) regulatory T cells after liver transplantation.
Transplantation proceedings 20100601
-
Relationship between everolimus blood concentration assessed using the Innofluor Certican Fluorescence Polarization Immunoassay and the Architect i System sirolimus chemiluminescent microparticle immunoassay.
Transplantation proceedings 20100601
-
Rapamycin inhibits activator protein-1 but not nuclear factor-kappaB activity of mature bone marrow-derived dendritic cells.
Transplantation proceedings 20100601
-
Posttransplantation therapeutic rapamycin concentration protects nitric oxide-related vascular endothelial function: comparative effects in rat thoracic aorta and coronary endothelial cell culture.
Transplantation proceedings 20100601
-
Long-term clinical results following stenting of the left main stem: insights from RESEARCH (Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital) and T-SEARCH (Taxus-Stent Evaluated at Rotterdam Cardiology Hospital) Registries.
JACC. Cardiovascular interventions 20100601
-
Strut coverage and vessel wall response to zotarolimus-eluting and bare-metal stents implanted in patients with ST-segment elevation myocardial infarction: the OCTAMI (Optical Coherence Tomography in Acute Myocardial Infarction) Study.
JACC. Cardiovascular interventions 20100601
-
A status report on drug-associated acne and acneiform eruptions.
Journal of drugs in dermatology : JDD 20100601
-
The phosphatidylinositol 3-kinase/Akt/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients.
Oncotarget 20100601
-
mTOR-mediated activation of p70 S6K induces differentiation of pluripotent human embryonic stem cells.
Cellular reprogramming 20100601
-
Hyperglycemia induced by tacrolimus and sirolimus is reversible in normal sprague-dawley rats.
Endocrine 20100601
-
Autism spectrum disorder is related to endoplasmic reticulum stress induced by mutations in the synaptic cell adhesion molecule, CADM1.
Cell death & disease 20100601
-
Initial experience with an everolimus-eluting, second-generation drug-eluting stent for treatment of intracranial atherosclerosis.
Journal of neurointerventional surgery 20100601
-
Involvement of heterogeneous ribonucleoprotein F in the regulation of cell proliferation via the mammalian target of rapamycin/S6 kinase 2 pathway.
The Journal of biological chemistry 20100528
-
mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs.
Science (New York, N.Y.) 20100528
-
Thrombotic microangiopathy after GVHD prophylaxis with tacrolimus/sirolimus: a call for use of consensus definition in reporting.
Blood 20100527
-
Late airway anastomotic dehiscence associated with sirolimus and migratory staples in a lung transplant recipient.
Transplantation 20100527
-
Smooth muscle cells orchestrate the endothelial cell response to flow and injury.
Circulation 20100525
-
Phosphatidic acid is a leukocyte chemoattractant that acts through S6 kinase signaling.
The Journal of biological chemistry 20100521
-
FOXO3a regulates glycolysis via transcriptional control of tumor suppressor TSC1.
The Journal of biological chemistry 20100521
-
[18F]Fluorodeoxyglucose positron emission tomography for outcome prediction of mammalian target of rapamycin inhibitor therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100520
-
Rapamycin and quasi-programmed aging: four years later.
Cell cycle (Georgetown, Tex.) 20100515
-
Conversion to sirolimus in African American renal allograft recipients undergoing early steroid withdrawal: intermediate-term risks and benefits.
Transplantation 20100515
-
Long-term vascular changes after drug-eluting stent implantation assessed by serial volumetric intravascular ultrasound analysis.
The American journal of cardiology 20100515
-
Quality of life in patients with advanced renal cell carcinoma treated with temsirolimus or interferon-alpha.
British journal of cancer 20100511
-
Single amino-acid changes that confer constitutive activation of mTOR are discovered in human cancer.
Oncogene 20100506
-
Everolimus-eluting versus paclitaxel-eluting stents in coronary artery disease.
The New England journal of medicine 20100506
-
Second-generation drug-eluting coronary stents.
The New England journal of medicine 20100506
-
Mammalian target of rapamycin signaling modulates photic entrainment of the suprachiasmatic circadian clock.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20100505
-
Everolimus and pazopanib: two new drugs for renal cell cancer.
The Medical letter on drugs and therapeutics 20100503
-
Late stent malapposition risk is higher after drug-eluting stent compared with bare-metal stent implantation and associates with late stent thrombosis.
European heart journal 20100501
-
mTOR inhibitor RAD001 (Everolimus) enhances the effects of imatinib in chronic myeloid leukemia by raising the nuclear expression of c-ABL protein.
Leukemia research 20100501
-
Combined treatment with cisplatin and sirolimus to enhance cell death in human mesothelioma.
The Journal of thoracic and cardiovascular surgery 20100501
-
Sirolimus and everolimus clearance in maintenance kidney and liver transplant recipients: diagnostic efficiency of the concentration/dose ratio for the prediction of trough steady-state concentrations.
Upsala journal of medical sciences 20100501
-
Effects of the novel protein kinase C inhibitor AEB071 (Sotrastaurin) on rat cardiac allograft survival using single agent treatment or combination therapy with cyclosporine, everolimus or FTY720.
Transplant international : official journal of the European Society for Organ Transplantation 20100501
-
Identification of functional FKB protein in Echinococcus granulosus: its involvement in the protoscolicidal action of rapamycin derivates and in calcium homeostasis.
International journal for parasitology 20100501
-
Intrarenal vascular resistance parameters in kidney transplant patients receiving calcineurin inhibitor-based or sirolimus-based regimens.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100501
-
Anaemia, microcytosis and sirolimus--is iron the missing link?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100501
-
Methylglyoxal activates Gcn2 to phosphorylate eIF2alpha independently of the TOR pathway in Saccharomyces cerevisiae.
Applied microbiology and biotechnology 20100501
-
IVUS radiofrequency analysis in the evaluation of the polymeric struts of the bioabsorbable everolimus-eluting device during the bioabsorption process.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100501
-
Randomized comparison of everolimus- and paclitaxel-eluting stents: pooled analysis of the 2-year clinical follow-up from the SPIRIT II and III trials.
European heart journal 20100501
-
Mammalian target of rapamycin regulates vascular endothelial growth factor-dependent liver cyst growth in polycystin-2-defective mice.
Hepatology (Baltimore, Md.) 20100501
-
Histology of highly echolucent regions in optical coherence tomography images from two patients with sirolimus-eluting stent restenosis.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100501
-
Sirolimus versus paclitaxel-eluting stents in small coronary vessels: long-term outcomes from a single-center registry.
Journal of cardiovascular medicine (Hagerstown, Md.) 20100501
-
Regulation of the autophagic machinery in human neutrophils.
European journal of immunology 20100501
-
Therapies for the medical management of persistent hypoglycaemia in two cases of inoperable malignant insulinoma.
European journal of endocrinology 20100501
-
The treatment of recurrent/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL) with everolimus results in clinical responses and mobilization of CLL cells into the circulation.
Cancer 20100501
-
Delayed re-endothelialization with rapamycin-coated stents is rescued by the addition of a glycogen synthase kinase-3beta inhibitor.
Cardiovascular research 20100501
-
In vitro and in vivo performance of a dual drug-eluting stent (DDES).
Biomaterials 20100501
-
Exendin-4 protects pancreatic beta cells from the cytotoxic effect of rapamycin by inhibiting JNK and p38 phosphorylation.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20100501
-
Indications, tolerance and complications of a sirolimus and calcineurin inhibitor immunosuppression regimen: intermediate experience in pediatric heart transplantation recipients.
Pediatric transplantation 20100501
-
Treatment with the mTOR inhibitor temsirolimus in patients with malignant PEComa.
Annals of oncology : official journal of the European Society for Medical Oncology 20100501
-
Comparison by optical coherence tomography of paclitaxel-eluting stents with sirolimus-eluting stents implanted in one coronary artery in one procedure. - 6-month follow-up -.
Circulation journal : official journal of the Japanese Circulation Society 20100501
-
Natural products in structure-assisted design of molecular cancer therapeutics.
Current pharmaceutical design 20100501
-
A Phase II trial of the oral mTOR inhibitor everolimus in relapsed Hodgkin lymphoma.
American journal of hematology 20100501
-
MCF-7 breast cancer cells selected for tamoxifen resistance acquire new phenotypes differing in DNA content, phospho-HER2 and PAX2 expression, and rapamycin sensitivity.
Cancer biology & therapy 20100501
-
Papillary renal cell carcinoma with cutaneous metastases.
The American journal of the medical sciences 20100501
-
Impact of angiographic and intravascular ultrasound features on clinical outcome after sirolimus-eluting stent implantation for de-novo lesions in nondiabetic and type 2 diabetic patients.
Coronary artery disease 20100501
-
Transforming growth factor beta 1 (TGF-beta1) and rapamycin synergize to effectively suppress human T cell responses via upregulation of FoxP3+ Tregs.
Transplant immunology 20100501
-
Giant warts in a kidney transplant patient: regression with sirolimus.
The British journal of dermatology 20100501
-
Personalized molecular targeted therapy in advanced, recurrent hepatocellular carcinoma after liver transplantation: a proof of principle.
Journal of hepatology 20100501
-
Predictor of subsequent target lesion revascularization in patients with drug-eluting stent restenosis undergoing percutaneous coronary intervention.
Journal of cardiology 20100501
-
Rapamycin extends maximal lifespan in cancer-prone mice.
The American journal of pathology 20100501
-
How to interpret phase II data for everolimus plus bevacizumab in renal cell carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100501
-
Phase II trial of bevacizumab and everolimus in patients with advanced renal cell carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100501
-
The initial extent of malapposition in ST-elevation myocardial infarction treated with drug-eluting stent: the usefulness of optical coherence tomography.
Yonsei medical journal 20100501
-
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.
Nature neuroscience 20100501
-
Mutant protein kinase C gamma that causes spinocerebellar ataxia type 14 (SCA14) is selectively degraded by autophagy.
Genes to cells : devoted to molecular & cellular mechanisms 20100501
-
A functional link between polo-like kinase 1 and the mammalian target-of-rapamycin pathway?
Cell cycle (Georgetown, Tex.) 20100501
-
Preferential increase in memory and regulatory subsets during T-lymphocyte immune reconstitution after Thymoglobulin induction therapy with maintenance sirolimus vs cyclosporine.
Transplant immunology 20100501
-
Calcineurin inhibitor-related cholestasis complicating lung transplantation.
The Annals of thoracic surgery 20100501
-
Novel immunosuppressive agents in kidney transplantation.
Clinical nephrology 20100501
-
Addition of induction therapy offsets the hazard of marked calcineurin minimization among renal transplant recipients treated with sirolimus.
Clinical nephrology 20100501
-
True comparison of different stents in the same coronary artery.
Circulation journal : official journal of the Japanese Circulation Society 20100501
-
Vascular response to overlapping everolimus-eluting stents. - Comparison with paclitaxel-eluting stents -.
Circulation journal : official journal of the Japanese Circulation Society 20100501
-
Everolimus in relapsed Hodgkin's lymphoma: something exciting or a case of caveat mTOR?
American journal of hematology 20100501
-
High incidence of thrombus formation at 18 months after paclitaxel-eluting stent implantation: angioscopic comparison with sirolimus-eluting stent.
American heart journal 20100501
-
Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy.
Cell cycle (Georgetown, Tex.) 20100501
-
Long-interval T2-weighted subtraction magnetic resonance imaging: a powerful new outcome measure in multiple sclerosis trials.
Annals of neurology 20100501
-
Longer-term outcomes of paclitaxel stent implantation as an initial treatment strategy for sirolimus-eluting stent restenosis.
The Journal of invasive cardiology 20100501
-
Sirolimus and tuberous sclerosis-associated renal angiomyolipomas.
Archives of disease in childhood 20100501
-
[Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma].
Aktuelle Urologie 20100501
-
[Gingival hyperplasia secondary to everolimus therapy].
Actas dermo-sifiliograficas 20100501
-
Paclitaxel- versus sirolimus-eluting stents for treatment of ST-segment elevation myocardial infarction: with analyses for diabetic and nondiabetic subpopulation.
JACC. Cardiovascular interventions 20100501
-
Optical coherence tomography assessment of in vivo vascular response after implantation of overlapping bare-metal and drug-eluting stents.
JACC. Cardiovascular interventions 20100501
-
10-year follow-up of the first Cypher stent implanted in human: an invasive evaluation with angiography, intravascular ultrasound, and optical coherence tomography.
JACC. Cardiovascular interventions 20100501
-
Calorie restriction: what recent results suggest for the future of ageing research.
European journal of clinical investigation 20100501
-
Immunosuppressive agents and bone disease in renal transplant patients with hypercalcemia.
Transplantation proceedings 20100501
-
De novo everolimus-based therapy in renal transplant recipients: effect on proteinuria and renal prognosis.
Transplantation proceedings 20100501
-
Once-a-day administration of everolimus, cyclosporine, and steroid after renal transplantation: a review of the rationale.
Transplantation proceedings 20100501
-
Once daily everolimus is safe and effective in de novo renal transplant recipients: six-month results of a pilot study.
Transplantation proceedings 20100501
-
Conversion of stable kidney transplant recipients from a twice-daily to once-daily everolimus regimen.
Transplantation proceedings 20100501
-
Conversion to rapamycin immunosuppression for malignancy after kidney transplantation.
Transplantation proceedings 20100501
-
Effects of sirolimus on human mesangial cells.
Transplantation proceedings 20100501
-
Liver transplantation due to iatrogenic injuries: two case reports.
Transplantation proceedings 20100501
-
Liver resection associated with mini porto-caval shunt as salvage treatment in patients with progression of hepatocellular carcinoma before liver transplantation: a case report.
Transplantation proceedings 20100501
-
Lower homocysteine levels in renal transplant recipients treated with everolimus: a possible link with a decreased cardiovascular risk?
Transplantation proceedings 20100501
-
Eighteen-month clinical safety and efficacy outcomes of sirolimus-, paclitaxel- and zotarolimus-drug eluting stents in diabetic patients undergoing percutaneous coronary intervention for complex coronary artery stenosis.
Annals of the Academy of Medicine, Singapore 20100501
-
The role of mTOR in memory CD8 T-cell differentiation.
Immunological reviews 20100501
-
A randomised comparison between everolimus-eluting stent and sirolimus-eluting stent in chronic coronary total occlusions. Rationale and design of the CIBELES (non-acute Coronary occlusion treated by EveroLimus-Eluting Stent) trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100501
-
Endothelial function rather than endothelial restoration is altered in paclitaxel- as compared to bare metal-, sirolimusand tacrolimus-eluting stents.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100501
-
Neuroendocrine gastroenteropancreatic tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Annals of oncology : official journal of the European Society for Medical Oncology 20100501
-
Present state of target therapy for disseminated renal cell carcinoma.
Immunotherapy 20100501
-
Regulation of survivin by PI3K/Akt/p70S6K1 pathway.
Biochemical and biophysical research communications 20100430
-
mTOR inhibitor rapamycin alone or combined with cisplatin inhibits growth of esophageal squamous cell carcinoma in nude mice.
Cancer letters 20100428
-
Impact of immunosuppressants on the therapeutic efficacy of in vitro-expanded CD4+CD25+Foxp3+ regulatory T cells in allotransplantation.
Transplantation 20100427
-
Interaction between everolimus and tacrolimus in renal transplant recipients: a pharmacokinetic controlled trial.
Transplantation 20100427
-
Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.
The Journal of biological chemistry 20100423
-
Sirolimus- versus paclitaxel-eluting stents for the treatment of coronary bifurcations results: from the COBIS (Coronary Bifurcation Stenting) Registry.
Journal of the American College of Cardiology 20100420
-
Rapamycin regulates endothelial cell migration through regulation of the cyclin-dependent kinase inhibitor p27Kip1.
The Journal of biological chemistry 20100416
-
Ribosomal protein S6 kinase is a critical downstream effector of the target of rapamycin complex 1 for long-term facilitation in Aplysia.
The Journal of biological chemistry 20100416
-
Long-term follow-up of patients with sirolimus-eluting stents for treatment of bare-metal in-stent restenosis.
International journal of cardiology 20100415
-
Long-term outcome after drug eluting stenting in patients with ST-segment elevation myocardial infarction: data from the REAL registry.
International journal of cardiology 20100415
-
Everolimus with reduced calcineurin inhibitor in thoracic transplant recipients with renal dysfunction: a multicenter, randomized trial.
Transplantation 20100415
-
Sensitive quantification of sirolimus and everolimus by LC-MS/MS with online sample cleanup.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100415
-
Comparison by meta-analysis of drug-eluting stents and bare metal stents for saphenous vein graft intervention.
The American journal of cardiology 20100415
-
Multicenter phase II study of everolimus in patients with previously treated metastatic gastric cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100410
-
Late and very late stent thrombosis after polymer-based sirolimus- or paclitaxel-eluting stent implantation in real-world clinical practice.
Chinese medical journal 20100405
-
Gender difference in patients with acute myocardial infarction treated by primary percutaneous coronary intervention in drug-eluting stent era.
Chinese medical journal 20100405
-
Absence of gender disparity in short-term clinical outcomes in patients with acute ST-segment elevation myocardial infarction undergoing sirolimus-eluting stent based primary coronary intervention: a report from Shanghai Acute Coronary Event (SACE) Registry.
Chinese medical journal 20100405
-
Comparison of long-term clinical outcome after successful implantation of Firebird sirolimus- and Taxus paclitaxel-eluting stents in Chinese population: analysis of a large single center registry.
Chinese medical journal 20100405
-
CD4+Foxp3+ regulatory T cells converted by rapamycin from peripheral CD4+CD25(-) naive T cells display more potent regulatory ability in vitro.
Chinese medical journal 20100405
-
Everolimus-eluting versus paclitaxel-eluting stents.
Lancet (London, England) 20100403
-
Everolimus-eluting versus paclitaxel-eluting stents.
Lancet (London, England) 20100403
-
The autophagy-lysosome pathway: a novel mechanism involved in the processing of oxidized LDL in human vascular endothelial cells.
Biochemical and biophysical research communications 20100402
-
Treatment of vertebral artery origin stenosis with anti-proliferative drug-eluting stents.
Journal of neuroimaging : official journal of the American Society of Neuroimaging 20100401
-
Fracture of a paclitaxol-eluting stent implanted for in-stent restenosis at the site of sirolimus-eluting stent fracture.
International journal of cardiology 20100401
-
Death caused by simultaneous subacute stent thrombosis of sirolimus-eluting stents in left anterior descending artery and left circumflex artery.
International journal of cardiology 20100401
-
Rapamycin inhibits proliferation and migration of hepatoma cells in vitro.
The Journal of surgical research 20100401
-
Rapamycin promotes the osteoblastic differentiation of human embryonic stem cells by blocking the mTOR pathway and stimulating the BMP/Smad pathway.
Stem cells and development 20100401
-
Involvement of mTOR and survivin inhibition in tamoxifen-induced apoptosis in human hepatoblastoma cell line HepG2.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100401
-
Increase in proteinuria >200 mg/g after late rejection is associated with poor graft survival.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100401
-
Impact of Cyclin B2 and Cell division cycle 2 on tubular hyperplasia in progressive chronic renal failure rats.
American journal of physiology. Renal physiology 20100401
-
Tuberous sclerosis complex: a brave new world?
Current opinion in neurology 20100401
-
A clinical and angiographic study of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with multivessel coronary artery disease. Study design and rationale of the EXECUTIVE trial.
Journal of cardiovascular medicine (Hagerstown, Md.) 20100401
-
Activation of mTOR signaling pathway contributes to survival of cervical cancer cells.
Gynecologic oncology 20100401
-
Targeting of VEGF-dependent transendothelial migration of cancer cells by bevacizumab.
Molecular oncology 20100401
-
Inhibition of target of rapamycin signaling and stress activate autophagy in Chlamydomonas reinhardtii.
Plant physiology 20100401
-
Implication of RICTOR in the mTOR inhibitor-mediated induction of insulin-like growth factor-I receptor (IGF-IR) and human epidermal growth factor receptor-2 (Her2) expression in gastrointestinal cancer cells.
Biochimica et biophysica acta 20100401
-
In vitro interaction of posaconazole with calcineurin inhibitors and sirolimus against zygomycetes.
The Journal of antimicrobial chemotherapy 20100401
-
Inhibition of glycolysis enhances cisplatin-induced apoptosis in ovarian cancer cells.
American journal of obstetrics and gynecology 20100401
-
A 3-year clinical outcome after percutaneous coronary intervention using sirolimus-eluting stent and off-pump coronary artery bypass grafting for the treatment of diabetic patients with multivessel disease.
Circulation journal : official journal of the Japanese Circulation Society 20100401
-
Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: an in vivo bioluminescence imaging study.
European journal of cancer (Oxford, England : 1990) 20100401
-
Activation of autophagy and Akt/CREB signaling play an equivalent role in the neuroprotective effect of rapamycin in neonatal hypoxia-ischemia.
Autophagy 20100401
-
Sirolimus-based immunosuppression is associated with increased survival after liver transplantation for hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 20100401
-
4-Substituted-7-azaindoles bearing a ureidobenzofuranone moiety as potent and selective, ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR).
Bioorganic & medicinal chemistry letters 20100401
-
New drug-eluting stent concepts.
Nature reviews. Cardiology 20100401
-
Long-term clinical outcome of chronic total occlusive lesions treated with drug-eluting stents: comparison of sirolimus-eluting and paclitaxel-eluting stents.
Circulation journal : official journal of the Japanese Circulation Society 20100401
-
RAD001 offers a therapeutic intervention through inhibition of mTOR as a potential strategy for esophageal cancer.
Oncology reports 20100401
-
Relevance of the mTOR signaling pathway in the pathophysiology of splenomegaly in rats with chronic portal hypertension.
Journal of hepatology 20100401
-
mTOR signaling and drug development in cancer.
Nature reviews. Clinical oncology 20100401
-
Real world, long-term outcomes comparison between paclitaxel-eluting and sirolimus-eluting stent platforms.
Journal of interventional cardiology 20100401
-
Two-year clinical registry follow-up of endothelial progenitor cell capture stent versus sirolimus-eluting bioabsorbable polymer-coated stent versus bare metal stents in patients undergoing primary percutaneous coronary intervention for ST elevation myocardial infarction.
Journal of interventional cardiology 20100401
-
Role of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway.
Genes to cells : devoted to molecular & cellular mechanisms 20100401
-
FDA approval summary: temsirolimus as treatment for advanced renal cell carcinoma.
The oncologist 20100401
-
Periadventitial rapamycin-eluting microbeads promote vein graft disease in long-term pig vein-into-artery interposition grafts.
Circulation. Cardiovascular interventions 20100401
-
In-hospital and 12-month postprocedural clinical outcome of coronary bifurcational lesion treatment with the endeavor stent.
Journal of interventional cardiology 20100401
-
Drug-eluting stents versus bare-metal stents in acute ST-segment elevation myocardial infarction. a single-center experience with long-term follow up.
The Journal of invasive cardiology 20100401
-
Drug-eluting stent versus bare-metal stent in acute ST-segment elevation myocardial infarction: a word of caution.
The Journal of invasive cardiology 20100401
-
Percutaneous interventions below the knee in patients with critical limb ischemia using drug eluting stents.
The Journal of cardiovascular surgery 20100401
-
Drug eluting stents versus PTA with GP IIb/IIIa blockade below the knee in patients with current ulcers--The BELOW Study.
The Journal of cardiovascular surgery 20100401
-
Missing data in repeated measures study.
Heart (British Cardiac Society) 20100401
-
Increased restenosis rates 12 months after coronary implantation of the sirolimus-eluting YUKON-choice stent compared to the paclitaxel-eluting TAXUS Stent.
Clinical cardiology 20100401
-
Thrombus in sirolimus-eluting stent identified by optical coherence tomography.
Clinical cardiology 20100401
-
Palliative chemotherapy for pancreatic malignancies.
The Surgical clinics of North America 20100401
-
Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma.
Molecular cancer therapeutics 20100401
-
Evaluation of a rapamycin-regulated serotype 2 adeno-associated viral vector in macaque parotid glands.
Oral diseases 20100401
-
Sirolimus- versus paclitaxel-eluting stents for the treatment of cardiac allograft vasculopathy.
JACC. Cardiovascular interventions 20100401
-
Monitoring in vivo absorption of a drug-eluting bioabsorbable stent with intravascular ultrasound-derived parameters a feasibility study.
JACC. Cardiovascular interventions 20100401
-
Catheter-induced stent occlusion: uncommon complication during diagnostic angiography.
JACC. Cardiovascular interventions 20100401
-
Polymer-free biolimus a9-coated stent demonstrates more sustained intimal inhibition, improved healing, and reduced inflammation compared with a polymer-coated sirolimus-eluting cypher stent in a porcine model.
Circulation. Cardiovascular interventions 20100401
-
A case of lipid core plaque progression and rupture at the edge of a coronary stent: elucidating the mechanisms of drug-eluting stent failure.
Circulation. Cardiovascular interventions 20100401
-
[Effect of rapamycin on apoptosis in human myelodysplastic syndrome cell line MUTZ-1 and its possible mechanisms].
Zhongguo shi yan xue ye xue za zhi 20100401
-
Can cyclosporine blood level be reduced to half after heart transplantation?
Transplantation proceedings 20100401
-
Combined sirolimus-calcineurin inhibitor immunosuppressive therapy in simultaneous heart and kidney transplantation: a retrospective analysis of a single hospital's experience.
Transplantation proceedings 20100401
-
The survival of heart transplant recipients using cyclosporine and everolimus is not inferior to that using cyclosporine and mycophenolate.
Transplantation proceedings 20100401
-
Sunitinib, sorafenib, temsirolimus or bevacizumab in the treatment of metastatic renal cell carcinoma: a review of health economic evaluations.
Journal of chemotherapy (Florence, Italy) 20100401
-
[Mammalian target of rapamycin inhibitors for the targeted therapy of non-small cell lung cancer].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20100401
-
[Neuroendocrine carcinoma of the lung: a diagnostic and therapeutic challenge].
Medizinische Klinik (Munich, Germany : 1983) 20100401
-
Effect and mechanism of panaxoside Rg1 on neovascularization in myocardial infarction rats.
Chinese journal of integrative medicine 20100401
-
Stem cell marker upregulation in normal cutaneous vessels following pulsed-dye laser exposure and its abrogation by concurrent rapamycin administration: implications for treatment of port-wine stain birthmarks.
Journal of cutaneous pathology 20100401
-
[Everolimus (RAD001/Afinitor) in the treatment of metastatic cell carcinoma].
Revue medicale de Liege 20100401
-
Paclitaxel and sirolimus eluting stents versus bare metal stents: long-term risk of stent thrombosis and other outcomes. From the Western Denmark Heart Registry.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100401
-
In vivo evaluation of stent strut distribution patterns in the bioabsorbable everolimus-eluting device: an OCT ad hoc analysis of the revision 1.0 and revision 1.1 stent design in the ABSORB clinical trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100401
-
Short- and long-term health related quality-of-life and anginal status of the Arterial Revascularisation Therapies Study part II, ARTS-II; sirolimus-eluting stents for the treatment of patients with multivessel coronary artery disease.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100401
-
Identification of annexin A13 as a regulator of chemotherapy resistance using random homozygous gene perturbation.
Analytical and quantitative cytology and histology 20100401
-
[Effect of sirolimus on capacity of splenic dendritic cells from traumatized mice in inducing T cell responses ex vivo].
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20100401
-
Rapamycin inhibits relapsing experimental autoimmune encephalomyelitis by both effector and regulatory T cells modulation.
Journal of neuroimmunology 20100330
-
First report on a series of HIV patients undergoing rapamycin monotherapy after liver transplantation.
Transplantation 20100327
-
Comparing an early corticosteroid/late calcineurin-free immunosuppression protocol to a sirolimus-, cyclosporine A-, and prednisone-based regimen for pancreas-kidney transplantation.
Transplantation 20100327
-
Efficacy and safety of zotarolimus-eluting and sirolimus-eluting coronary stents in routine clinical care (SORT OUT III): a randomised controlled superiority trial.
Lancet (London, England) 20100327
-
Sorting out drug-eluting stents.
Lancet (London, England) 20100327
-
Bafilomycins produced in culture by Streptomyces spp. isolated from marine habitats are potent inhibitors of autophagy.
Journal of natural products 20100326
-
Letter by Virmani et al regarding article, 'Drug-eluting stents in animals and patients: where do we stand today?'.
Circulation 20100323
-
An expeditious route to fluorinated rapamycin analogues by utilising mutasynthesis.
Chembiochem : a European journal of chemical biology 20100322
-
Lesion complexity determines arterial drug distribution after local drug delivery.
Journal of controlled release : official journal of the Controlled Release Society 20100319
-
Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation.
Oncogene 20100318
-
TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity.
Oncogene 20100318
-
5-year clinical outcomes of the ARTS II (Arterial Revascularization Therapies Study II) of the sirolimus-eluting stent in the treatment of patients with multivessel de novo coronary artery lesions.
Journal of the American College of Cardiology 20100316
-
Immunosuppressant neurotoxicity in rat brain models: oxidative stress and cellular metabolism.
Chemical research in toxicology 20100315
-
Comparison of outcomes between Zotarolimus- and sirolimus-eluting stents in patients with ST-segment elevation acute myocardial infarction.
The American journal of cardiology 20100315
-
Rapamycin for Kaposi's sarcoma and graft-versus-host disease in bone marrow transplant recipient.
Transplantation 20100315
-
Pregnancy restores the regenerative capacity of the aged liver via activation of an mTORC1-controlled hyperplasia/hypertrophy switch.
Genes & development 20100315
-
mTOR Ser-2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of action.
The Journal of biological chemistry 20100312
-
Rapamycin inhibits oncogenic intestinal ion channels and neoplasia in APC(Min/+) mice.
Oncogene 20100311
-
Stem-cell transplantation for sickle cell disease.
The New England journal of medicine 20100311
-
Phase II trial of the oral mammalian target of rapamycin inhibitor everolimus in relapsed or refractory Waldenstrom macroglobulinemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100310
-
Nocardiopsins: new FKBP12-binding macrolide polyketides from an Australian marine-derived actinomycete, Nocardiopsis sp.
Chemistry (Weinheim an der Bergstrasse, Germany) 20100308
-
Neuroendocrine tumors of the pancreas: what's new. Highlights from the '2010 ASCO Gastrointestinal Cancers Symposium'. Orlando, FL, USA. January 22-24, 2010.
JOP : Journal of the pancreas 20100305
-
Liquid chromatography-tandem mass spectrometry method for determination of Sirolimus coated drug eluting nano porous carbon stents.
Biomedical chromatography : BMC 20100301
-
Rapamycin potentiates the effects of paclitaxel in endometrial cancer cells through inhibition of cell proliferation and induction of apoptosis.
International journal of cancer 20100301
-
Comparative pharmacokinetics of RAD001 (everolimus) in normal and tumor-bearing rodents.
Cancer chemotherapy and pharmacology 20100301
-
Increased frequency of regulatory T cells and selection of highly potent CD62L+ cells during treatment of human lung transplant recipients with rapamycin.
Transplant international : official journal of the European Society for Organ Transplantation 20100301
-
Sirolimus monotherapy as maintenance immunosuppression: a multicenter experience.
Transplant international : official journal of the European Society for Organ Transplantation 20100301
-
Rapamycin (sirolimus) in tuberous sclerosis associated pediatric central nervous system tumors.
Pediatric blood & cancer 20100301
-
Rapamycin, unlike cyclosporine A, enhances suppressive functions of in vitro-induced CD4+CD25+ Tregs.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100301
-
Autophagy is involved in starvation response and cell death in Blastocystis.
Microbiology (Reading, England) 20100301
-
[Impact of immunotherapy in metastatic kidney cancer in Germany after introduction of new target therapy--results of a telephone survey of the German Society of Immuno- and Targeted Therapy (DGFIT)].
Aktuelle Urologie 20100301
-
Rapamycin and the transcription factor C/EBPbeta as a switch in osteoclast differentiation: implications for lytic bone diseases.
Journal of molecular medicine (Berlin, Germany) 20100301
-
Sirolimus and cyclosporine A alter barrier function in renal proximal tubular cells through stimulation of ERK1/2 signaling and claudin-1 expression.
American journal of physiology. Renal physiology 20100301
-
Dissecting the role of mTOR: lessons from mTOR inhibitors.
Biochimica et biophysica acta 20100301
-
Cytocidal amino acid starvation of Saccharomyces cerevisiae and Candida albicans acetolactate synthase (ilv2{Delta}) mutants is influenced by the carbon source and rapamycin.
Microbiology (Reading, England) 20100301
-
Rapamycin ameliorates PKD resulting from conditional inactivation of Pkd1.
Journal of the American Society of Nephrology : JASN 20100301
-
AZD6244 (ARRY-142886) enhances the antitumor activity of rapamycin in mouse models of human hepatocellular carcinoma.
Cancer 20100301
-
The release kinetics of drug eluting stents containing sirolimus as coated drug: role of release media.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100301
-
Fission yeast TORC1 regulates phosphorylation of ribosomal S6 proteins in response to nutrients and its activity is inhibited by rapamycin.
Journal of cell science 20100301
-
Bioequivalence testing of immunosuppressants: concepts and misconceptions.
Kidney international. Supplement 20100301
-
Effects of aging and gender on muscle mass and regulation of Akt-mTOR-p70s6k related signaling in the F344BN rat model.
Mechanisms of ageing and development 20100301
-
Simulation of sirolimus exposures and population variability immediately post renal transplantation: importance of the patient's CYP3A5 genotype in tailoring treatment.
Biopharmaceutics & drug disposition 20100301
-
Protection from rapamycin-induced apoptosis by insulin-like growth factor-I is partially dependent on protein kinase C signaling.
Cancer research 20100301
-
Everolimus.
Clinical cancer research : an official journal of the American Association for Cancer Research 20100301
-
Recent advances and future directions in the management of metastatic renal cell carcinoma.
Anti-cancer agents in medicinal chemistry 20100301
-
Restenosis rates following vertebral artery origin stenting: does stent type make a difference?
The Journal of invasive cardiology 20100301
-
Conversion of cyclosporine to sirolimus before 12 months is associated with marked improvement in renal function and low proteinuria in a South African renal transplant population.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20100301
-
[Recent progress in the molecular-targeting treatment of neuroendocrine tumors].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20100301
-
Molecular basis of different outcomes for drug-eluting stents that release sirolimus or tacrolimus.
Current opinion in drug discovery & development 20100301
-
Treatment of non-left main bifurcation lesions using the sirolimus-eluting stent: A comparison of chronic outcomes of cross-over single stenting and crush stenting.
Journal of cardiology 20100301
-
Rapamycin and tacrolimus differentially modulate acute graft-versus-host disease in rats after liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20100301
-
Does 'late catch-up' exist in drug-eluting stents: insights from a serial quantitative coronary angiography analysis of sirolimus versus paclitaxel-eluting stents.
American heart journal 20100301
-
Long-term outcome of percutaneous catheter intervention for de novo coronary bifurcation lesions with drug-eluting stents or bare-metal stents.
American heart journal 20100301
-
Everolimus (RAD001) in the treatment of advanced renal cell carcinoma: a review.
The oncologist 20100301
-
Treatment strategies and clinical trial design in ADPKD.
Advances in chronic kidney disease 20100301
-
Predictive value of C-reactive protein after drug-eluting stent implantation.
Future cardiology 20100301
-
Use of tacrolimus and the development of posttransplant diabetes mellitus: a Brazilian single-center, observational study.
Transplantation proceedings 20100301
-
Recovery of renal function in heart transplantation patients after conversion from a calcineurin inhibitor-based therapy to sirolimus.
Transplantation proceedings 20100301
-
Cell phenotype evaluation at various sites after skin transplantation and FTY720 plus sirolimus therapy.
Transplantation proceedings 20100301
-
Sirolimus in combination with FTY720: analysis of urinary and serum parameters.
Transplantation proceedings 20100301
-
Rescue immunosuppression with mammalian target of rapamycin inhibitor drugs in liver transplantation.
Transplantation proceedings 20100301
-
mTOR signaling: a central pathway to pathogenesis in systemic lupus erythematosus?
Discovery medicine 20100301
-
Long-term clinical outcomes after sirolimus-eluting stent implantation in dialysis patients.
International heart journal 20100301
-
Rapamycin-mediated FOXO1 inactivation reduces the anticancer efficacy of rapamycin.
Anticancer research 20100301
-
[Recent advance in tuberous sclerosis-related genes and their expression].
Zhonghua bing li xue za zhi = Chinese journal of pathology 20100301
-
[Vessel response evaluation by optical coherence tomography after drug-eluting stent implantation in the left main coronary artery].
Giornale italiano di cardiologia (2006) 20100301
-
Sirolimus-induced severe hypertriglyceridemia in a lung transplant recipient.
Transplantation 20100227
-
StatBite: FDA oncology drug product approvals in 2009.
Journal of the National Cancer Institute 20100224
-
Maintenance of long-term clinical benefit with sirolimus-eluting stents in patients with ST-segment elevation myocardial infarction 3-year results of the SESAMI (sirolimus-eluting stent versus bare-metal stent in acute myocardial infarction) trial.
Journal of the American College of Cardiology 20100223
-
Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice.
Blood 20100218
-
Rapid inactivation of proteins by rapamycin-induced rerouting to mitochondria.
Developmental cell 20100216
-
Long-term effectiveness and safety of sirolimus stent implantation for coronary in-stent restenosis results of the TRUE (Tuscany Registry of sirolimus for unselected in-stent restenosis) registry at 4 years.
Journal of the American College of Cardiology 20100216
-
Three-year outcome of drug-eluting stent implantation for coronary artery bifurcation lesions.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100215
-
Comparison of 2-year clinical outcomes with sirolimus and paclitaxel-eluting stents for patients with diabetes: results of the Registro Regionale AngiopLastiche Emilia-Romagna Registry.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100215
-
Initiation of neuronal differentiation requires PI3-kinase/TOR signalling in the vertebrate neural tube.
Developmental biology 20100215
-
Systemic rapamycin without loading dose for restenosis prevention after coronary bare metal stent implantation.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100215
-
Noninvasive detection of target modulation following phosphatidylinositol 3-kinase inhibition using hyperpolarized 13C magnetic resonance spectroscopy.
Cancer research 20100215
-
Supplemental islet infusions restore insulin independence after graft dysfunction in islet transplant recipients.
Transplantation 20100215
-
The impact of body mass index on the one year outcomes of patients treated by percutaneous coronary intervention with Biolimus- and Sirolimus-eluting stents (from the LEADERS Trial).
The American journal of cardiology 20100215
-
Mammalian target of rapamycin signaling and autophagy: roles in lymphangioleiomyomatosis therapy.
Proceedings of the American Thoracic Society 20100215
-
Systemic rapamycin to prevent restenosis: a glimpse to the past?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100215
-
Is diabetes a leveler of efficacy of DES types?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100215
-
Sirolimus and temsirolimus for epithelioid angiomyolipoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100210
-
Clinical activity of mTOR inhibition with sirolimus in malignant perivascular epithelioid cell tumors: targeting the pathogenic activation of mTORC1 in tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100210
-
A randomized comparison of the Endeavor zotarolimus-eluting stent versus the TAXUS paclitaxel-eluting stent in de novo native coronary lesions 12-month outcomes from the ENDEAVOR IV trial.
Journal of the American College of Cardiology 20100209
-
Autophagy impairment inhibits differentiation of glioma stem/progenitor cells.
Brain research 20100208
-
The rapamycin-derivative RAD001 (everolimus) inhibits cell viability and interacts with the Akt-mTOR-p70S6K pathway in human medullary thyroid carcinoma cells.
Molecular and cellular endocrinology 20100205
-
p70 S6 kinase limits tumor necrosis factor-alpha-induced interleukin-6 synthesis in osteoblast-like cells.
Molecular and cellular endocrinology 20100205
-
Insulin-stimulated interaction with 14-3-3 promotes cytoplasmic localization of lipin-1 in adipocytes.
The Journal of biological chemistry 20100205
-
Rapamycin enhances the susceptibility of both androgen-dependent and -independent prostate carcinoma cells to docetaxel.
Chinese medical journal 20100205
-
A phase II pilot study of tacrolimus/sirolimus GVHD prophylaxis for sibling donor hematopoietic stem cell transplantation using 3 conditioning regimens.
Blood 20100204
-
Steroid avoidance using sirolimus and cyclosporine in pediatric renal transplantation: one year analysis.
Pediatric transplantation 20100201
-
Cost-effectiveness of immunosuppressive regimens in renal transplant recipients in Germany: a model approach.
The European journal of health economics : HEPAC : health economics in prevention and care 20100201
-
Rapamycin-insensitive up-regulation of MMP2 and other genes in tuberous sclerosis complex 2-deficient lymphangioleiomyomatosis-like cells.
American journal of respiratory cell and molecular biology 20100201
-
Metabolic control of antifungal drug resistance.
Fungal genetics and biology : FG & B 20100201
-
Novel mechanism of rapamycin in GVHD: increase in interstitial regulatory T cells.
Bone marrow transplantation 20100201
-
Lower incidence of cytomegalovirus infection with everolimus versus mycophenolate mofetil in de novo cardiac transplant recipients: a randomized, multicenter study.
Transplant infectious disease : an official journal of the Transplantation Society 20100201
-
Rapamycin or tacrolimus alone fails to resist cardiac allograft accelerated rejection mediated by alloreactive CD4(+) memory T cells in mice.
Transplant immunology 20100201
-
Multicentric outcome analysis of sirolimus-based immunosuppression in 252 liver transplant recipients.
Transplant international : official journal of the European Society for Organ Transplantation 20100201
-
Improved outcomes using tacrolimus/sirolimus for graft-versus-host disease prophylaxis with a reduced-intensity conditioning regimen for allogeneic hematopoietic cell transplant as treatment of myelofibrosis.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20100201
-
Treatment of renal artery in-stent restenosis with sirolimus-eluting stents.
Vascular medicine (London, England) 20100201
-
Rapamycin: the cure for all that ails.
Journal of molecular cell biology 20100201
-
Clinical and angiographic outcomes with an everolimus-eluting stent in large coronary arteries: the SPIRIT III 4.0 mm registry.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100201
-
Coronary stenting with the sirolimus-eluting stent in patients with restenosis after intracoronary brachytherapy: results from the prospective multicentre German Cypher Stent Registry.
Clinical research in cardiology : official journal of the German Cardiac Society 20100201
-
Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species.
Free radical research 20100201
-
Bim is the key mediator of glucocorticoid-induced apoptosis and of its potentiation by rapamycin in human myeloma cells.
Biochimica et biophysica acta 20100201
-
Calcineurin inhibitors affect B cell antibody responses indirectly by interfering with T cell help.
Clinical and experimental immunology 20100201
-
Rapamycin inhibits lung metastasis of B16 melanoma cells through down-regulating alphav integrin expression and up-regulating apoptosis signaling.
Cancer science 20100201
-
Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle.
American journal of physiology. Cell physiology 20100201
-
Tubular toxicity in sirolimus- and cyclosporine-based transplant immunosuppression strategies: an ancillary study from a randomized controlled trial.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20100201
-
Delayed correlation of mRNA and protein expression in rapamycin-treated cells and a role for Ggc1 in cellular sensitivity to rapamycin.
Molecular & cellular proteomics : MCP 20100201
-
Quantitative nuclear proteomics identifies mTOR regulation of DNA damage response.
Molecular & cellular proteomics : MCP 20100201
-
Potential role of everolimus in inducing cholestasis.
Annals of oncology : official journal of the European Society for Medical Oncology 20100201
-
Effect of everolimus on cell viability in nonfunctioning pituitary adenomas.
The Journal of clinical endocrinology and metabolism 20100201
-
Coronary stenting with the sirolimus-eluting stent in clinical practice: final results from the prospective multicenter German Cypher Stent Registry.
Journal of interventional cardiology 20100201
-
Ultra fast liquid chromatography-tandem mass spectrometry routine method for simultaneous determination of cyclosporin A, tacrolimus, sirolimus, and everolimus in whole blood using deuterated internal standards for cyclosporin A and everolimus.
Therapeutic drug monitoring 20100201
-
RAD 001 (everolimus) prevents mTOR and Akt late re-activation in response to imatinib in chronic myeloid leukemia.
Journal of cellular biochemistry 20100201
-
Tubular epithelial cell and podocyte apoptosis with de novo sirolimus based immunosuppression in renal allograft recipients with DGF.
Histology and histopathology 20100201
-
Comparison of neointimal coverage of sirolimus-eluting stents and paclitaxel-eluting stents using optical coherence tomography at 9 months after implantation.
Circulation journal : official journal of the Japanese Circulation Society 20100201
-
Drug-eluting stent fracture: incidence, contributing factors, and clinical implications.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100201
-
MYC activity mitigates response to rapamycin in prostate cancer through 4EBP1-mediated inhibition of autophagy.
Autophagy 20100201
-
Experience with everolimus (RAD001), an oral mammalian target of rapamycin inhibitor, in patients with systemic mastocytosis.
Leukemia & lymphoma 20100201
-
Pharmacokinetic sub-study in the SPIRIT III Randomized and Controlled Trial of XIENCE V everolimus eluting coronary stent system.
Journal of interventional cardiology 20100201
-
Clinical predictors of proteinuria after conversion to sirolimus in kidney transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100201
-
Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.
Nature medicine 20100201
-
A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer.
Molecular endocrinology (Baltimore, Md.) 20100201
-
Broadening the therapeutic scope for rapamycin treatment.
Autophagy 20100201
-
New Drugs2010, PART 1.
Nursing 20100201
-
Resveratrol and rapamycin: are they anti-aging drugs?
BioEssays : news and reviews in molecular, cellular and developmental biology 20100201
-
Surgical biology for the clinician: vascular effects of immunosuppression.
Canadian journal of surgery. Journal canadien de chirurgie 20100201
-
Major adverse cardiac events in patients with moderate to severe renal insufficiency treated with first-generation drug-eluting stents.
The American journal of cardiology 20100201
-
Augmentation of autophagy by mTOR-inhibition in myocardial infarction: When size matters.
Autophagy 20100201
-
Rapamycin inhibits cholangiocyte regeneration by blocking interleukin-6-induced activation of signal transducer and activator of transcription 3 after liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20100201
-
Rapid improvement of nephrogenic systemic fibrosis with rapamycin therapy: possible role of phospho-70-ribosomal-S6 kinase.
Journal of the American Academy of Dermatology 20100201
-
Why do patients develop proteinuria with sirolimus? Do we have the answer?
American journal of kidney diseases : the official journal of the National Kidney Foundation 20100201
-
Paclitaxel-eluting versus sirolimus-eluting stents in diabetes mellitus: a report from the National Heart, Lung, and Blood Institute Dynamic Registry.
Circulation. Cardiovascular interventions 20100201
-
Dependence on phosphoinositide 3-kinase and RAS-RAF pathways drive the activity of RAF265, a novel RAF/VEGFR2 inhibitor, and RAD001 (Everolimus) in combination.
Molecular cancer therapeutics 20100201
-
Outcomes of unselected recipients of sirolimus-eluting stents: the Cypher stent U.S. post-marketing surveillance registry.
The Journal of invasive cardiology 20100201
-
Outcomes of overlapping bare-metal stents with sirolimus-eluting stents for long lesions in small coronary vessels.
The Journal of invasive cardiology 20100201
-
Diffuse alveolar hemorrhage induced by everolimus.
Chest 20100201
-
Sotrastaurin and everolimus pharmacokinetics after single-dose coadministration.
International journal of clinical pharmacology and therapeutics 20100201
-
A pooled gender based analysis comparing the XIENCE V(R) everolimus-eluting stent and the TAXUS paclitaxel-eluting stent in male and female patients with coronary artery disease, results of the SPIRIT II and SPIRIT III studies: two-year analysis.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100201
-
Cost-effectiveness of the Endeavor stent in de novo native coronary artery lesions updated with contemporary data.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100201
-
A comparison of clinical presentations, angiographic patterns and outcomes of in-stent restenosis between bare metal stents and drug eluting stents.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100201
-
Effect of drug-eluting stents in patients with acute ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention: a meta-analysis of randomised trials and an adjusted indirect comparison.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100201
-
Comments on the article by Routledge et al 'Three-year clinical outcome of percutaneous treatment of bifurcation lesions in multivessel coronary artery disease with the sirolimus-eluting stent: insights from the Arterial Revascularisation Therapies Study, part II (ARTS II)'.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100201
-
Rapamycin inhibits VEGF-induced microvascular hyperpermeability in vivo.
Microcirculation (New York, N.Y. : 1994) 20100201
-
Long-term blood vessel removal with combined laser and topical rapamycin antiangiogenic therapy: implications for effective port wine stain treatment.
Lasers in surgery and medicine 20100201
-
Impact of multiple and long sirolimus-eluting stent implantation on 3-year clinical outcomes in the j-Cypher Registry.
JACC. Cardiovascular interventions 20100201
-
Impact of drug-eluting stent length on outcomes less is more...more or less.
JACC. Cardiovascular interventions 20100201
-
Difference of neointimal formational pattern and incidence of thrombus formation among 3 kinds of stents: an angioscopic study.
JACC. Cardiovascular interventions 20100201
-
[Effects of rapamycin-loaded poly(lactic-co-glycolic) acid nanoparticles on distribution of cell cycle, expression of p27 protein, and proliferation of human umbilical arterial vascular smooth muscle cell in vitro].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20100201
-
Comparison of long-term results of drug-eluting stent and bare metal stent implantation in heart transplant recipients with coronary artery disease.
Kardiologia polska 20100201
-
Influence of drug-eluting stent on inflammation during restenosis in a porcine coronary model.
Acta cardiologica 20100201
-
The pathophysiology of tuberous sclerosis complex.
Epilepsia 20100201
-
[Intravascular ultrasound evaluation on the efficacy of national made Firebird stents comparing with Cypher stents].
Zhonghua xin xue guan bing za zhi 20100201
-
[Treatment of locally advanced renal tumors].
Actas urologicas espanolas 20100201
-
Sirolimus-eluting stents versus paclitaxel-eluting stents in patients with chronic renal insufficiency.
Journal of interventional cardiology 20100201
-
Resolvin E1 receptor activation signals phosphorylation and phagocytosis.
The Journal of biological chemistry 20100129
-
Effect of different immunosuppressive schedules on recurrence-free survival after liver transplantation for hepatocellular carcinoma.
Transplantation 20100127
-
Cyclosporine lowering with everolimus or mycophenolate to preserve renal function in heart recipients: a randomized study.
Transplantation 20100127
-
Sirolimus-eluting stent implantation in small coronary arteries: a three dimensional intravascular ultrasound study from the SIRIUS trial.
International journal of cardiology 20100121
-
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20100120
-
[mTOR and non-small cell lung cancer].
Zhongguo fei ai za zhi = Chinese journal of lung cancer 20100120
-
Second-generation everolimus-eluting and paclitaxel-eluting stents in real-life practice (COMPARE): a randomised trial.
Lancet (London, England) 20100116
-
Everolimus or paclitaxel stents in real life: go COMPARE.
Lancet (London, England) 20100116
-
Preclinical in vivo evaluation of rapamycin in human malignant peripheral nerve sheath explant xenograft.
International journal of cancer 20100115
-
Omega-3 polyunsaturated fatty acids affect sirolimus exposure in kidney transplant recipients on calcineurin inhibitor-free regimen.
Transplantation 20100115
-
Myxoma virus virotherapy for glioma in immunocompetent animal models: optimizing administration routes and synergy with rapamycin.
Cancer research 20100115
-
The somatostatin analogue octreotide confers sensitivity to rapamycin treatment on pituitary tumor cells.
Cancer research 20100115
-
Beyond rapalog therapy: preclinical pharmacology and antitumor activity of WYE-125132, an ATP-competitive and specific inhibitor of mTORC1 and mTORC2.
Cancer research 20100115
-
Outcome of undersized drug-eluting stents for percutaneous coronary intervention of saphenous vein graft lesions.
The American journal of cardiology 20100115
-
Hybrid inhibitors of phosphatidylinositol 3-kinase (PI3K) and the mammalian target of rapamycin (mTOR): design, synthesis, and superior antitumor activity of novel wortmannin-rapamycin conjugates.
Journal of medicinal chemistry 20100114
-
Dysregulation of mTOR signaling in fragile X syndrome.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20100113
-
Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster.
Cell metabolism 20100106
-
Depletion of mammalian target of rapamycin (mTOR) via siRNA mediated knockdown leads to stabilization of beta-catenin and elicits distinct features of cardiomyocyte hypertrophy.
FEBS letters 20100104
-
Oral ulcers after a transplant.
The British journal of oral & maxillofacial surgery 20100101
-
Everolimus-induced pneumonitis: report of the first case in a liver transplant recipient and review of treatment options.
Transplant international : official journal of the European Society for Organ Transplantation 20100101
-
Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma.
Journal of neuro-oncology 20100101
-
Rapamycin promotes arterial thrombosis in vivo: implications for everolimus and zotarolimus eluting stents.
European heart journal 20100101
-
Celecoxib reduces the effects of acute and chronic UVB exposure in mice treated with therapeutically relevant immunosuppressive drugs.
International journal of cancer 20100101
-
Late conversion of tacrolimus to sirolimus in a prednisone-free immunosuppression regimen in renal transplant patients.
Clinical transplantation 20100101
-
mTOR inhibitor everolimus ameliorates progressive tubular dysfunction in chronic renal failure rats.
Biochemical pharmacology 20100101
-
The PI3K/Akt and mTOR/P70S6K signaling pathways in human uveal melanoma cells: interaction with B-Raf/ERK.
Investigative ophthalmology & visual science 20100101
-
Acute rejection after paediatric heart transplantation: far less common and less severe.
Transplant international : official journal of the European Society for Organ Transplantation 20100101
-
Repeat renal allografts treated with sirolimus, cyclosporine, anti-thymocyte globulin induction and continuous steroids achieve similar immunosuppressive efficacy as primary transplants.
Clinical transplantation 20100101
-
Long-term results after conversion from calcineurin inhibitors to sirolimus in renal transplant patients.
Clinical transplantation 20100101
-
Acute rejection in low-toxicity regimens: clinical impact and risk factors in the Symphony study.
Clinical transplantation 20100101
-
Phase I clinical and pharmacokinetic study of RAD001 (everolimus) administered daily to Japanese patients with advanced solid tumors.
Japanese journal of clinical oncology 20100101
-
The sensing of essential amino acid deficiency in the anterior piriform cortex, that requires the uncharged tRNA/GCN2 pathway, is sensitive to wortmannin but not rapamycin.
Pharmacology, biochemistry, and behavior 20100101
-
Cost-effectiveness of temsirolimus for first line treatment of advanced renal cell carcinoma.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20100101
-
Rapamycin inhibits yeast nucleotide excision repair independently of tor kinases.
Toxicological sciences : an official journal of the Society of Toxicology 20100101
-
Rapamycin impairs metabolism-secretion coupling in rat pancreatic islets by suppressing carbohydrate metabolism.
The Journal of endocrinology 20100101
-
Mammalian target of rapamycin (mTOR) inhibition as a potential antiepileptogenic therapy: From tuberous sclerosis to common acquired epilepsies.
Epilepsia 20100101
-
Glucocorticoids increase NPY gene expression in the arcuate nucleus by inhibiting mTOR signaling in rat hypothalamic organotypic cultures.
Peptides 20100101
-
Rapamycin and CCI-779 inhibit the mammalian target of rapamycin signalling in hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver 20100101
-
Noncanonical TGF-beta pathways, mTORC1 and Abl, in renal interstitial fibrogenesis.
American journal of physiology. Renal physiology 20100101
-
Preliminary characterization of oral lesions associated with inhibitors of mammalian target of rapamycin in cancer patients.
Cancer 20100101
-
Aortic dissection in a patient treated by sunitinib for metastatic renal cell carcinoma.
Annals of oncology : official journal of the European Society for Medical Oncology 20100101
-
A novel mTOR activating protein protects dopamine neurons against oxidative stress by repressing autophagy related cell death.
Journal of neurochemistry 20100101
-
Expression of metabolically targeted biomarkers in endometrial carcinoma.
Gynecologic oncology 20100101
-
Systemic drugs for restenosis prevention: old idea, new drugs.
Cardiology 20100101
-
Preventing restenosis after implantation of bare stents with oral rapamycin: a randomized angiographic and intravascular ultrasound study with a 5-year clinical follow-up.
Cardiology 20100101
-
Failed rescue therapy with rapamycin after paraquat intoxication.
Clinical toxicology (Philadelphia, Pa.) 20100101
-
An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study.
European heart journal 20100101
-
Transcription factor GATA4 inhibits doxorubicin-induced autophagy and cardiomyocyte death.
The Journal of biological chemistry 20100101
-
The application of electrostatic dry powder deposition technology to coat drug-eluting stents.
Pharmaceutical research 20100101
-
A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1.
Molecular and cellular biology 20100101
-
Sirolimus-induced signaling modifications in Kaposi's sarcoma with resolution in a liver transplant recipient.
Clinical transplantation 20100101
-
Proteinuria after conversion to sirolimus in kidney transplant recipients: impact of pre-existing proteinuria, graft function, and angiotensin-converting enzyme inhibitors/angiotensin-receptor antagonists.
Clinical transplantation 20100101
-
Unravelling the endovascular microenvironment by optical coherence tomography.
European heart journal 20100101
-
Daily oral everolimus activity in patients with metastatic pancreatic neuroendocrine tumors after failure of cytotoxic chemotherapy: a phase II trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100101
-
Pharmacological modification of dendritic cells to promote their tolerogenicity in transplantation.
Methods in molecular biology (Clifton, N.J.) 20100101
-
Recent progress in percutaneous coronary intervention: evolution of the drug-eluting stents, focus on the XIENCE V drug-eluting stent.
Coronary artery disease 20100101
-
Treatment of mild-moderate calcified coronary lesions with sirolimus-eluting stent: real world data from a single center.
Coronary artery disease 20100101
-
The impact of sirolimus on hepatocyte proliferation after living donor liver transplantation.
Clinical transplantation 20100101
-
Anthropogenic factors and the risk of highly pathogenic avian influenza H5N1: prospects from a spatial-based model.
Veterinary research 20100101
-
Influence of selective immunosuppressive drugs on the healing of exposed dogs' dental pulp capped with mineral trioxide aggregate.
Journal of endodontics 20100101
-
Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3.
Brain : a journal of neurology 20100101
-
Pharmacological inhibition of phosphoinositide 3 and TOR kinases improves survival of Drosophila melanogaster.
Rejuvenation research 20100101
-
Mammalian target of rapamycin (mTOR) induces proliferation and de-differentiation responses to three coordinate pathophysiologic stimuli (mechanical strain, hypoxia, and extracellular matrix remodeling) in rat bladder smooth muscle.
The American journal of pathology 20100101
-
Drug-eluting stents for the treatment of acute myocardial infarction: the view to the HORIZONS.
Heart, lung & circulation 20100101
-
Bevacizumab, sorafenib tosylate, sunitinib and temsirolimus for renal cell carcinoma: a systematic review and economic evaluation.
Health technology assessment (Winchester, England) 20100101
-
The role of the Akt/mTOR pathway in tobacco carcinogen-induced lung tumorigenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 20100101
-
Vorinostat enhances the activity of temsirolimus in renal cell carcinoma through suppression of survivin levels.
Clinical cancer research : an official journal of the American Association for Cancer Research 20100101
-
Small-molecule inhibitors of phosphatidylinositol 3-kinase/Akt signaling inhibit Wnt/beta-catenin pathway cross-talk and suppress medulloblastoma growth.
Cancer research 20100101
-
Early (fifth day) vs. late (sixth month) steroid withdrawal in renal transplant recipients treated with Neoral(®) plus Rapamune(®): four-yr results of a randomized monocenter study.
Clinical transplantation 20100101
-
Reduction of cyclosporine following the introduction of everolimus in maintenance heart transplant recipients: a pilot study.
Transplant international : official journal of the European Society for Organ Transplantation 20100101
-
Stage 2 combination testing of rapamycin with cytotoxic agents by the Pediatric Preclinical Testing Program.
Molecular cancer therapeutics 20100101
-
The ATM inhibitor KU-55933 suppresses cell proliferation and induces apoptosis by blocking Akt in cancer cells with overactivated Akt.
Molecular cancer therapeutics 20100101
-
Management of chronic allograft dysfunction by switch over to rapamycin.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20100101
-
Temsirolimus.
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20100101
-
Quantitation of sirolimus using liquid chromatography-tandem mass spectrometry (LC-MS-MS).
Methods in molecular biology (Clifton, N.J.) 20100101
-
Persistent effects of everolimus on strength of experimental wounds in intestine and fascia.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20100101
-
Progress in the management of advanced renal cell carcinoma (RCC).
Aktuelle Urologie 20100101
-
Long-term laryngeal allograft survival using low-dose everolimus.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20100101
-
Lingual angioedema associated with everolimus.
Acta oncologica (Stockholm, Sweden) 20100101
-
Effect of rapamycin on lifespan in Drosophila.
Geriatrics & gerontology international 20100101
-
Meta-analysis of five randomized clinical trials comparing sirolimus- versus paclitaxel-eluting stents in patients with diabetes mellitus.
The American journal of cardiology 20100101
-
Sirolimus-eluting stent implantation for ostial stenosis of left main coronary artery after Bentall operation in aortitis syndrome.
Journal of cardiology 20100101
-
Incidence and predictors of very late (>or=4 years) major cardiac adverse events in the DESIRE (Drug-Eluting Stents in the Real World)-Late registry.
JACC. Cardiovascular interventions 20100101
-
First clinical experience of 'flower petal stenting': a novel technique for the treatment of coronary bifurcation lesions.
JACC. Cardiovascular interventions 20100101
-
The artisan approach for stenting bifurcation lesions.
JACC. Cardiovascular interventions 20100101
-
Anti-CD34 antibodies immobilized on the surface of sirolimus-eluting stents enhance stent endothelialization.
JACC. Cardiovascular interventions 20100101
-
Drug-eluting stent endothelium: presence or dysfunction.
JACC. Cardiovascular interventions 20100101
-
Increased restenosis rate after implantation of drug-eluting stents in patients with elevated serum activity of matrix metalloproteinase-2 and -9.
JACC. Cardiovascular interventions 20100101
-
Regulation of gene expression in hepatic cells by the mammalian Target of Rapamycin (mTOR).
PloS one 20100101
-
Lkb1 inactivation is sufficient to drive endometrial cancers that are aggressive yet highly responsive to mTOR inhibitor monotherapy.
Disease models & mechanisms 20100101
-
[Stromal progenitor cells and blood leukocytes after implantation of drug-eluting stents].
Kardiologiia 20100101
-
Comparison of three rapamycin dosing schedules in A/J Tsc2+/- mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneous tuberous sclerosis related tumors.
Journal of translational medicine 20100101
-
[First-line therapy of metastatic renal cell carcinoma--update 2009].
Onkologie 20100101
-
[Current aspects of second-line and sequence therapy of metastatic renal cell carcinoma].
Onkologie 20100101
-
[Outlook: Future therapy of renal cell carcinoma].
Onkologie 20100101
-
Thrombotic microangiopathy following intestinal transplantation: a single center experience.
Transplantation proceedings 20100101
-
Effects of immunosuppressive drugs on rat renal ischemia reperfusion injury.
Transplantation proceedings 20100101
-
Everolimus versus azathioprine in a cyclosporine and ketoconazole-based immunosuppressive therapy in kidney transplant: 3-year follow-up of an open-label, prospective, cohort, comparative clinical trial.
Transplantation proceedings 20100101
-
Results of the conversion to everolimus in renal transplant recipients with posttransplantation malignancies.
Transplantation proceedings 20100101
-
Effectiveness and cost of replacing a calcineurin inhibitor with sirolimus to slow the course of chronic kidney disease in renal allografts.
Transplantation proceedings 20100101
-
Conversion to sirolimus allows preservation of renal function in kidney and kidney-pancreas allograft recipients.
Transplantation proceedings 20100101
-
South American Heart Transplantation Registry of patients receiving everolimus in their immunosuppressive regimens.
Transplantation proceedings 20100101
-
Everolimus in lung transplantation in Chile.
Transplantation proceedings 20100101
-
Sirolimus in kidney transplant donors and clinical and histologic improvement in recipients: rat model.
Transplantation proceedings 20100101
-
In vitro and in vivo characterization of novel biodegradable polymers for application as drug-eluting stent coatings.
Journal of biomaterials science. Polymer edition 20100101
-
mTOR inhibitor-associated dermatologic and mucosal problems.
Clinical transplantation 20100101
-
Toxic tacrolimus blood levels with rifampin administration in a renal transplant recipient.
Annals of transplantation 20100101
-
Sirolimus-eluting stent fractures leading to restenosis in cardiac allograft vasculopathy.
Cardiovascular revascularization medicine : including molecular interventions 20100101
-
Rapamycin induces autophagy and exacerbates metabolism associated complications in a mouse model of type 1 diabetes.
Indian journal of experimental biology 20100101
-
New therapeutic strategies for renal cell carcinoma.
Urologic nursing 20100101
-
Evaluation of the firebird sirololimus eluting stent in all comers with coronary artery stenosis.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20100101
-
[Toxic effect of immunosuppression agent Everolimus on insuloma cells and pancreatic islets of SD rat].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100101
-
Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease.
PloS one 20100101
-
A therapeutic exploratory study to determine the efficacy and safety of calcineurin-inhibitor-free de-novo immunosuppression after liver transplantation: CILT.
BMC surgery 20100101
-
VEGF secretion by neuroendocrine tumor cells is inhibited by octreotide and by inhibitors of the PI3K/AKT/mTOR pathway.
Neuroendocrinology 20100101
-
Sirolimus-based immunosuppression in kidney transplantation for type 2 diabetic nephropathy.
Urologia internationalis 20100101
-
Pulmonary toxicity associated with sirolimus following kidney transplantation: computed tomography findings.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20100101
-
Rapamycin inhibits re-endothelialization after percutaneous coronary intervention by impeding the proliferation and migration of endothelial cells and inducing apoptosis of endothelial progenitor cells.
Texas Heart Institute journal 20100101
-
[Renal cell carcinoma management and therapies in 2010].
Bulletin du cancer 20100101
-
[mTOR inhibitors: temsirolimus and everolimus in the treatment of renal cell carcinoma].
Bulletin du cancer 20100101
-
[Targeted therapies: sequential and combined treatments].
Bulletin du cancer 20100101
-
[Management of side effects associated with antiangiogenic treatment in renal cell carcinoma].
Bulletin du cancer 20100101
-
[Advanced renal carcinomas with special situations. How to treat them?].
Bulletin du cancer 20100101
-
[Signalling pathways in renal-cell carcinoma: from the molecular biology to the future therapy].
Bulletin du cancer 20100101
-
Epidermal growth factor induces HCCR expression via PI3K/Akt/mTOR signaling in PANC-1 pancreatic cancer cells.
BMC cancer 20100101
-
Anti-CD154 mAb and rapamycin induce T regulatory cell mediated tolerance in rat-to-mouse islet transplantation.
PloS one 20100101
-
A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma.
BMC cancer 20100101
-
Severe aphthous stomatitis associated with oral calcineurin and mTOR inhibitors.
International journal of dermatology 20100101
-
Significant sirolimus and dronedarone interaction in a kidney transplant recipient.
The Annals of pharmacotherapy 20100101
-
Different immunosuppressive combinations on T-cell regulation in renal transplant recipients.
American journal of nephrology 20100101
-
Rapamycin inhibits IGF-1 stimulated cell motility through PP2A pathway.
PloS one 20100101
-
Accelerated wound healing by mTOR activation in genetically defined mouse models.
PloS one 20100101
-
[Change in regulations for dispensing immunosuppressants to patients who have undergone a kidney transplant].
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20100101
-
Xenotransplantation of hepatocytes in rats with acute liver failure using sirolimus for immunosuppression.
The Journal of international medical research 20100101
-
mTOR regulates the invasive properties of synovial fibroblasts in rheumatoid arthritis.
Molecular medicine (Cambridge, Mass.) 20100101
-
Rationale and design of a randomized clinical comparison of everolimus-eluting (Xience v/Promus) and sirolimus-eluting (cypher select+) coronary stents in unselected patients with coronary heart disease.
Cardiology 20100101
-
mTOR signaling in cancer cell motility and tumor metastasis.
Critical reviews in eukaryotic gene expression 20100101
-
Rapamycin pharmacokinetic and pharmacodynamic relationships in osteosarcoma: a comparative oncology study in dogs.
PloS one 20100101
-
Drug-eluting stent thrombosis 1,659 days after stent deployment: case report and literature review.
Texas Heart Institute journal 20100101
-
New inhibitors of the PI3K-Akt-mTOR pathway: insights into mTOR signaling from a new generation of Tor Kinase Domain Inhibitors (TORKinibs).
Current topics in microbiology and immunology 20100101
-
Q-TWiST analysis of patients receiving temsirolimus or interferon alpha for treatment of advanced renal cell carcinoma.
PharmacoEconomics 20100101
-
Rapamycin in combination with donor-specific CD4+CD25+Treg cells amplified in vitro might be realize the immune tolerance in clinical organ transplantation.
Cellular immunology 20100101
-
Choice of immunosuppression influences cytomegalovirus DNAemia in cynomolgus monkey (Macaca fascicularis) islet allograft recipients.
Cell transplantation 20100101
-
Comparison of the effect of preinterventional arterial remodeling on intimal hyperplasia after implantation of a sirolimus- or paclitaxel-eluting stent.
Cardiology 20100101
-
Efficacy of sirolimus-eluting stents compared with paclitaxel-eluting stents in an unselected population with coronary artery disease: 24-month outcomes of patients in a prospective non-randomized registry in Southern Turkey.
International journal of medical sciences 20100101
-
[Percutaneous copronary intervention using sirolimus-eluting stents may improve long-term prognosis of elderly women].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20100101
-
Development of encapsulating peritoneal sclerosis in a renal transplant recipient on sirolimus immunotherapy.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20100101
-
Inhibition of the mammalian target of rapamycin (mTOR) in advanced pancreatic cancer: results of two phase II studies.
BMC cancer 20100101
-
Peripheral blood T regulatory cell counts may not predict transplant rejection.
BMC immunology 20100101
-
Combination of rapamycin and IL-2 do not affect antigen presentation ability of rat B cell and could promote Tregs proliferation and inhibitory activity.
Cellular immunology 20100101
-
[Interstitial pneumonitis from everolimus].
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20100101
-
HIV-1 inhibits autophagy in bystander macrophage/monocytic cells through Src-Akt and STAT3.
PloS one 20100101
-
Severe stomatitis complicating immune-suppressive switch after cardiac transplantation.
Acta chirurgica Belgica 20100101
-
Similar early complication rate in simultaneous pancreas and kidney recipients on tacrolimus/mycophenolate mofetil versus tacrolimus/sirolimus immunosuppressive regimens.
Transplantation proceedings 20100101
-
Calcineurin inhibitors in renal transplantation still needed but in reduced doses: a review.
Transplantation proceedings 20100101
-
Antivascular endothelial growth factor in diabetic retinopathy.
Developments in ophthalmology 20100101
-
Mammalian target of rapamycin (mTOR) regulates TLR3 induced cytokines in human oral keratinocytes.
Molecular immunology 20100101
-
The effects of rapamycin on lens epithelial cell proliferation, migration, and matrix formation: an in vitro study.
Molecular vision 20100101
-
Cytostatic and anti-angiogenic effects of temsirolimus in refractory mantle cell lymphoma.
Journal of hematology & oncology 20100101
-
Study protocol: a pilot study to determine the safety and efficacy of induction-therapy, de novo MPA and delayed mTOR-inhibition in liver transplant recipients with impaired renal function. PATRON-study.
BMC nephrology 20100101
-
Asymptomatic migration of a sirolimus-eluting stent into the aorta.
Internal medicine (Tokyo, Japan) 20100101
-
A randomized pilot study of systemic immunosuppression in the treatment of age-related macular degeneration with choroidal neovascularization.
Retina (Philadelphia, Pa.) 20100101
-
Metabolic engineering of resveratrol and other longevity boosting compounds.
BioFactors (Oxford, England) 20100101
-
Life span extension by resveratrol, rapamycin, and metformin: The promise of dietary restriction mimetics for an healthy aging.
BioFactors (Oxford, England) 20100101
-
The DTH effector response and IL-2 are unaffected by cyclosporine A in autoimmune B6D2F1 mice.
Cellular immunology 20100101
-
Rationale and design of EXPLORE: a randomized, prospective, multicenter trial investigating the impact of recanalization of a chronic total occlusion on left ventricular function in patients after primary percutaneous coronary intervention for acute ST-elevation myocardial infarction.
Trials 20100101
-
Antitumour activity of a potent MEK inhibitor RDEA119/BAY 869766 combined with rapamycin in human orthotopic primary pancreatic cancer xenografts.
BMC cancer 20100101
-
Activated mammalian target of rapamycin is a potential therapeutic target in gastric cancer.
BMC cancer 20100101
-
Thrombogenicity of sirolimus-eluting stents and bare metal stents: evaluation in the early phase after stent implantation.
In vivo (Athens, Greece) 20100101
-
Rapamycin therapy for renal, brain, and skin lesions in a tuberous sclerosis patient.
Renal failure 20100101
-
Pretreatment with intraluminal rapamycin nanoparticle perfusion inhibits neointimal hyperplasia in a rabbit vein graft model.
International journal of nanomedicine 20100101
-
Small coronary vessel angioplasty: outcomes and technical considerations.
Vascular health and risk management 20100101
-
Rapamycin sensitizes T-ALL cells to dexamethasone-induced apoptosis.
Journal of experimental & clinical cancer research : CR 20100101
-
Improved outcome after 'bottom-up' immunosuppression in liver transplant recipients with preoperative renal impairment.
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20100101
-
Targeted therapy in lymphoma.
Journal of hematology & oncology 20100101
-
Rrd1 isomerizes RNA polymerase II in response to rapamycin.
BMC molecular biology 20100101
-
Teaching an old drug new tricks: metformin as a targeted therapy for lung cancer.
Seminars in thoracic and cardiovascular surgery 20100101
-
A comprehensive map of the mTOR signaling network.
Molecular systems biology 20100101
-
Primary PCI for acute anterior wall MI with pulmonary edema and left anterior descending artery ostial stenosis.
Indian heart journal 20100101
-
Preclinical evaluation of KIT/PDGFRA and mTOR inhibitors in gastrointestinal stromal tumors using small animal FDG PET.
Journal of experimental & clinical cancer research : CR 20100101
-
Niclosamide prevents the formation of large ubiquitin-containing aggregates caused by proteasome inhibition.
PloS one 20100101
-
Clinical studies with sirolimus, zotarolimus, everolimus, and biolimus A9 drug-eluting stent systems.
Current pharmaceutical design 20100101
-
Sirolimus and its analogs and its effects on vascular diseases.
Current pharmaceutical design 20100101
-
The Drosophila FoxA ortholog Fork head regulates growth and gene expression downstream of Target of rapamycin.
PloS one 20100101
-
Is it possible to optimize the use of targeted therapies in the treatment of renal cell carcinoma?
Tumori 20100101
-
Perspectives in the development of novel treatment approaches.
Tumori 20100101
-
Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy.
Cell death & disease 20100101
-
[Financial justification of investments into special diet for patients with phenylketonuria].
Medicinski pregled 20100101
-
[Long-term follow-up use of 'cypher' sirolimus-eluting stents in patients with coronary heart disease after coronary artery bypass grafting with occlusive lesions of the coronary artery].
Vestnik rentgenologii i radiologii 20100101
-
Rapamycin increases the p53/MDM2 protein ratio and p53-dependent apoptosis by translational inhibition of mdm2 in cancer cells.
Cancer letters 20091228
-
Impact of reduced nephron mass on cyclosporine- and/or sirolimus-induced nephrotoxicity.
Transplantation 20091227
-
Bortezomib can suppress activation of rapamycin-resistant memory T cells without affecting regulatory T-cell viability in non-human primates.
Transplantation 20091227
-
A chemical genetic screen for mTOR pathway inhibitors based on 4E-BP-dependent nuclear accumulation of eIF4E.
Chemistry & biology 20091224
-
Coronary aneurysm and very late stent thrombosis formation associated with sirolimus-eluting stent implantation.
Chinese medical journal 20091220
-
Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction.
The Journal of biological chemistry 20091218
-
Breakthrough of the year. The runners-up.
Science (New York, N.Y.) 20091218
-
[Autosomal dominant polycystic kidney disease (ADPKD): rapamycin as a new treatment option].
Praxis 20091216
-
Pharmacologic induction of CD8+ T cell memory: better living through chemistry.
Science translational medicine 20091216
-
Three-dimensional time-of-flight secondary ion mass spectrometry imaging of a pharmaceutical in a coronary stent coating as a function of elution time.
Analytical chemistry 20091215
-
TOR-driven aging: speeding car without brakes.
Cell cycle (Georgetown, Tex.) 20091215
-
Pseudo-DNA damage response in senescent cells.
Cell cycle (Georgetown, Tex.) 20091215
-
Histopathology of clinical coronary restenosis in drug-eluting versus bare metal stents.
The American journal of cardiology 20091215
-
Prolonged survival of composite facial allografts in non-human primates associated with posttransplant lymphoproliferative disorder.
Transplantation 20091215
-
EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy.
Science signaling 20091215
-
Beneficial effects of Mammalian target of rapamycin inhibition on left ventricular remodeling after myocardial infarction.
Journal of the American College of Cardiology 20091215
-
Assimilating the current clinical data of fully bioabsorbable stents.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091215
-
Novel fully bioabsorbable salicylate-based sirolimus-eluting stent.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091215
-
OrbusNeich fully absorbable coronary stent platform incorporating dual partitioned coatings.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091215
-
NEVOâ„¢: a new generation of sirolimus-eluting coronary stent.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091215
-
Everolimus-eluting bioabsorbable stent--Abbot Vascular programme.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091215
-
Allogeneic hematopoietic stem-cell transplantation for sickle cell disease.
The New England journal of medicine 20091210
-
Hematopoietic stem-cell transplantation for adults with sickle cell disease.
The New England journal of medicine 20091210
-
Structural identification and characterization of potential degradants of zotarolimus on zotarolimus-coated drug-eluting stents.
Journal of pharmaceutical and biomedical analysis 20091205
-
Blockade of Hsp20 phosphorylation exacerbates cardiac ischemia/reperfusion injury by suppressed autophagy and increased cell death.
Circulation research 20091204
-
Limited sampling strategies for sirolimus after pediatric renal transplantation.
Pediatric transplantation 20091201
-
Optical coherence tomography evaluation of zotarolimus-eluting stents at 9-month follow-up: comparison with sirolimus-eluting stents.
Heart (British Cardiac Society) 20091201
-
Phosphorylation of translation factors in response to anoxia in turtles, Trachemys scripta elegans: role of the AMP-activated protein kinase and target of rapamycin signalling pathways.
Molecular and cellular biochemistry 20091201
-
Rapid regression of lymphadenopathy upon rapamycin treatment in a child with autoimmune lymphoproliferative syndrome.
Pediatric blood & cancer 20091201
-
Treatment with sirolimus ameliorates tacrolimus-induced autoimmune cytopenias after solid organ transplant.
Pediatric blood & cancer 20091201
-
Quantitative coronary angiography in the current era: principles and applications.
Journal of interventional cardiology 20091201
-
Rapamycin impairs trabecular bone acquisition from high-dose but not low-dose intermittent parathyroid hormone treatment.
Journal of cellular physiology 20091201
-
Rapamycin induces the TGFbeta1/Smad signaling cascade in renal mesangial cells upstream of mTOR.
Cellular signalling 20091201
-
Transfer from ciclosporin to mycophenolate-sirolimus immunosuppression for chronic renal disease after heart transplantation: safety and efficacy of two regimens.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091201
-
Rapamycin has dual opposing effects on proteinuric experimental nephropathies: is it a matter of podocyte damage?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091201
-
Rapamycin protects against rotenone-induced apoptosis through autophagy induction.
Neuroscience 20091201
-
Quality of life in patients with metastatic renal cell carcinoma: the importance of patient-reported outcomes.
Cancer treatment reviews 20091201
-
The carina angle-new geometrical parameter associated with periprocedural side branch compromise and the long-term results in coronary bifurcation lesions with main vessel stenting only.
Journal of interventional cardiology 20091201
-
Emerging drugs for coronary restenosis: the role of systemic oral agents the in stent era.
Expert opinion on emerging drugs 20091201
-
A phase I/II study of the safety and efficacy of the addition of sirolimus to tacrolimus/methotrexate graft versus host disease prophylaxis after allogeneic haematopoietic cell transplantation in paediatric acute lymphoblastic leukaemia (ALL).
British journal of haematology 20091201
-
CDKs as therapeutic targets for the human genetic disease tuberous sclerosis?
European journal of clinical investigation 20091201
-
Five-year clinical outcomes after coronary stenting of chronic total occlusion using sirolimus-eluting stents: insights from the rapamycin-eluting stent evaluated at Rotterdam Cardiology Hospital-(Research) Registry.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091201
-
Exploring mammalian target of rapamycin (mTOR) inhibition for treatment of mantle cell lymphoma and other hematologic malignancies.
Leukemia & lymphoma 20091201
-
Rapamycin enhances lifespan: at last, an advantage for transplant recipients?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091201
-
Pulse mTOR inhibitor treatment effectively controls cyst growth but leads to severe parenchymal and glomerular hypertrophy in rat polycystic kidney disease.
American journal of physiology. Renal physiology 20091201
-
The multifunctional role of mTOR in innate immunity: implications for transplant immunity.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20091201
-
Long-term follow-up of neointimal coverage of sirolimus-eluting stents--evaluation with optical coherence tomography.
Circulation journal : official journal of the Japanese Circulation Society 20091201
-
Lack of clinical benefit of improved angiographic results with sirolimus-eluting stents compared with paclitaxel and zotarolimus-eluting stents in patients with acute myocardial infarction undergoing percutaneous coronary intervention.
Circulation journal : official journal of the Japanese Circulation Society 20091201
-
Effect of itraconazole on the pharmacokinetics of everolimus administered by different routes in rats.
Biopharmaceutics & drug disposition 20091201
-
mTOR regulates skeletal muscle regeneration in vivo through kinase-dependent and kinase-independent mechanisms.
American journal of physiology. Cell physiology 20091201
-
Effects of chronic overload on muscle hypertrophy and mTOR signaling in young adult and aged rats.
The journals of gerontology. Series A, Biological sciences and medical sciences 20091201
-
Significance and management of proteinuria in kidney transplant recipients.
Journal of the American Society of Nephrology : JASN 20091201
-
Five-year clinical follow-up after implantation of the Endeavor zotarolimus-eluting stent: ENDEAVOR I, first-in-human study.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091201
-
TOR complex 2: a signaling pathway of its own.
Trends in biochemical sciences 20091201
-
Characterization of p70 S6 kinase 1 in early development of mouse embryos.
Developmental dynamics : an official publication of the American Association of Anatomists 20091201
-
Mammalian target of rapamycin is a critical regulator of cardiac hypertrophy in spontaneously hypertensive rats.
Hypertension (Dallas, Tex. : 1979) 20091201
-
The rationale for mTOR inhibition in epithelial ovarian cancer.
Expert opinion on investigational drugs 20091201
-
Low toxicity regimens in renal transplantation: a country subset analysis of the Symphony study.
Transplant international : official journal of the European Society for Organ Transplantation 20091201
-
Evaluation of in vivo antineoplastic effects of rapamycin in patients with chemotherapy-refractory AML.
European journal of internal medicine 20091201
-
Pharmacological retention of oral mucosa progenitor/stem cells.
Journal of dental research 20091201
-
Oral rapamycin attenuates atherosclerosis without affecting the arterial responsiveness of resistance vessels in apolipoprotein E-deficient mice.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20091201
-
Targeting mTOR globally in cancer: thinking beyond rapamycin.
Cell cycle (Georgetown, Tex.) 20091201
-
Emerging treatment combinations: integrating therapy into clinical practice.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20091201
-
Targeting translation in acute myeloid leukemia: a new paradigm for therapy?
Cell cycle (Georgetown, Tex.) 20091201
-
Impact of sirolimus on the recurrence of hepatocellular carcinoma after liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20091201
-
Improvement of renal function after the switch from a calcineurin inhibitor to everolimus in liver transplant recipients with chronic renal dysfunction.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20091201
-
Delayed neointimalization on drug-eluting stents--speculation from optical coherence tomography.
Circulation journal : official journal of the Japanese Circulation Society 20091201
-
Metastatic renal cell carcinoma: current standards of care.
Clinical journal of oncology nursing 20091201
-
Management of mTOR inhibitor side effects.
Clinical journal of oncology nursing 20091201
-
The role of mTOR in bladder cancer.
Cancer biology & therapy 20091201
-
Comparison of sirolimus and paclitaxel-eluting stents for complex coronary lesions: an intravascular ultrasound study.
The Korean journal of internal medicine 20091201
-
Rapamycin versus methotrexate in early diffuse systemic sclerosis: results from a randomized, single-blind pilot study.
Arthritis and rheumatism 20091201
-
Intravesical delivery of rapamycin suppresses tumorigenesis in a mouse model of progressive bladder cancer.
Cancer prevention research (Philadelphia, Pa.) 20091201
-
The molecular, the bad, and the ugly: preventing bladder cancer via mTOR inhibition.
Cancer prevention research (Philadelphia, Pa.) 20091201
-
Are we totally clear?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091201
-
The long-term results of the 'Endeavor' stent.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091201
-
Rationale and design of the Patient Related OuTcomes with Endeavor versus Cypher stenting Trial (PROTECT): randomized controlled trial comparing the incidence of stent thrombosis and clinical events after sirolimus or zotarolimus drug-eluting stent implantation.
American heart journal 20091201
-
Clinical and angiographic comparison of everolimus-eluting and paclitaxel-eluting stents in small coronary arteries: a post hoc analysis of the SPIRIT III randomized trial.
American heart journal 20091201
-
Clinical development of temsirolimus, a novel mTOR inhibitor, for treatment of advanced malignancies.
Seminars in oncology 20091201
-
Intravenous temsirolimus in cancer patients: clinical pharmacology and dosing considerations.
Seminars in oncology 20091201
-
Clinical trial experience with temsirolimus in patients with advanced renal cell carcinoma.
Seminars in oncology 20091201
-
Mammalian target of rapamycin: discovery of rapamycin reveals a signaling pathway important for normal and cancer cell growth.
Seminars in oncology 20091201
-
Temsirolimus in mantle cell lymphoma and other non-Hodgkin lymphoma subtypes.
Seminars in oncology 20091201
-
Evaluating temsirolimus activity in multiple tumors: a review of clinical trials.
Seminars in oncology 20091201
-
Preprocedural inflammation does not affect neointimal hyperplasia following everolimus-eluting stent implantation.
The Journal of invasive cardiology 20091201
-
Late-acquired stent malapposition after sirolimus-eluting stent implantation following acute coronary syndrome: angiographic, IVUS, OCT and coronary angioscopic observation.
The Journal of invasive cardiology 20091201
-
Chinese 'Firebird' brand sirolimus-eluting stent fracture.
The Journal of invasive cardiology 20091201
-
Very late subacute thrombosis of a sirolimus-eluting stent after 57 months.
The Journal of invasive cardiology 20091201
-
Translational modulation of proteins expressed from bicistronic vectors.
Molecular imaging 20091201
-
Effects of delayed rapamycin treatment on renal fibrosis and inflammation in experimental ischemia reperfusion injury.
Transplantation proceedings 20091201
-
Potential differences in kidney allograft outcomes between ethnicities when converting to sirolimus base immunosuppression.
Transplantation proceedings 20091201
-
Renal function outcomes in kidney transplant recipients after conversion to everolimus-based immunosuppression regimen with CNI reduction or elimination.
Transplantation proceedings 20091201
-
Improved 24-hour blood pressure control with sirolimus versus calcineurin inhibitor based immunosuppression in renal transplant recipients.
Transplantation proceedings 20091201
-
Immunosuppression using the mammalian target of rapamycin (mTOR) inhibitor everolimus: pilot study shows significant cognitive and affective improvement.
Transplantation proceedings 20091201
-
Three year follow-up of the sirolimus-eluting stent and the paclitaxel-eluting stent in daily practice.
Clinical cardiology 20091201
-
Prognostic values of C-reactive protein levels on clinical outcome after implantation of sirolimus-eluting stents in patients on hemodialysis.
Circulation. Cardiovascular interventions 20091201
-
In-hospital and mid-term clinical outcomes after percutaneous coronary intervention with the use of sirolimus- or paclitaxel-eluting stents.
Kardiologia polska 20091201
-
Inhibition of mammalian target of rapamycin as a therapeutic strategy in the management of bladder cancer.
Cancer biology & therapy 20091201
-
[Benefits of proliferation signal inhibitors beyond immunosuppression. Vascular protection and experience in heart transplantation].
Nephrologie & therapeutique 20091201
-
[Proliferation signal inhibitors: what therapeutic protocols are followed in 2009?].
Nephrologie & therapeutique 20091201
-
[Replacing calcineurin inhibitors with proliferation signal inhibitors after kidney transplantation: indications, results, and disadvantages].
Nephrologie & therapeutique 20091201
-
The first-generation drug-eluting stents and coronary endothelial dysfunction.
JACC. Cardiovascular interventions 20091201
-
3-year clinical follow-up of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with de novo coronary artery lesions: the SPIRIT II trial (Clinical Evaluation of the Xience V Everolimus Eluting Coronary Stent System in the Treatment of Patients with de novo Native Coronary Artery Lesions).
JACC. Cardiovascular interventions 20091201
-
Long-term clinical and economic analysis of the Endeavor zotarolimus-eluting stent versus the cypher sirolimus-eluting stent: 3-year results from the ENDEAVOR III trial (Randomized Controlled Trial of the Medtronic Endeavor Drug [ABT-578] Eluting Coronary Stent System Versus the Cypher Sirolimus-Eluting Coronary Stent System in De Novo Native Coronary Artery Lesions).
JACC. Cardiovascular interventions 20091201
-
Late safety, efficacy, and cost-effectiveness of a zotarolimus-eluting stent compared with a paclitaxel-eluting stent in patients with de novo coronary lesions: 2-year follow-up from the ENDEAVOR IV trial (Randomized, Controlled Trial of the Medtronic Endeavor Drug [ABT-578] Eluting Coronary Stent System Versus the Taxus Paclitaxel-Eluting Coronary Stent System in De Novo Native Coronary Artery Lesions).
JACC. Cardiovascular interventions 20091201
-
Clinical outcomes after unrestricted implantation of everolimus-eluting stents.
JACC. Cardiovascular interventions 20091201
-
Safety and effectiveness of the Endeavor zotarolimus-eluting stent in real-world clinical practice: 12-month data from the E-Five registry.
JACC. Cardiovascular interventions 20091201
-
Evaluation in 3 months duration of neointimal coverage after zotarolimus-eluting stent implantation by optical coherence tomography: the ENDEAVOR OCT trial.
JACC. Cardiovascular interventions 20091201
-
Progression of late stent malapposition beyond 2 years after sirolimus-eluting stent implantation.
JACC. Cardiovascular interventions 20091201
-
Quantifying pharmacologic suppression of cellular senescence: prevention of cellular hypertrophy versus preservation of proliferative potential.
Aging 20091201
-
[Are stents eluting sirolimus and paclitaxel equally efficacious?].
Kardiologia polska 20091201
-
Rationale and design for the PAINT randomized trial.
Arquivos brasileiros de cardiologia 20091201
-
Temsirolimus for the treatment of mantle cell lymphoma.
Expert review of hematology 20091201
-
Drug repositioning using in silico compound profiling.
Future medicinal chemistry 20091201
-
Cyclin D1 induction by benzo[a]pyrene-7,8-diol-9,10-epoxide via the phosphatidylinositol 3-kinase/Akt/MAPK- and p70s6k-dependent pathway promotes cell transformation and tumorigenesis.
The Journal of biological chemistry 20091127
-
Fibrogenesis in kidney transplantation: potential targets for prevention and therapy.
Transplantation 20091127
-
Everolimus with very low-exposure cyclosporine a in de novo kidney transplantation: a multicenter, randomized, controlled trial.
Transplantation 20091127
-
Discovery of potent and selective inhibitors of the mammalian target of rapamycin (mTOR) kinase.
Journal of medicinal chemistry 20091126
-
A rapamycin-sensitive signaling pathway is essential for the full expression of persistent pain states.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20091125
-
Regulation of SREBP1c expression by mTOR signaling in hepatocytes.
The Kobe journal of medical sciences 20091124
-
If mammalian target of metformin indirectly is mammalian target of rapamycin, then the insulin-like growth factor-1 receptor axis will audit the efficacy of metformin in cancer clinical trials.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091120
-
The role of mTORC1 pathway in intestinal tumorigenesis.
Cell cycle (Georgetown, Tex.) 20091115
-
Clinical outcomes after sirolimus-eluting, paclitaxel-eluting, and bare metal stents (from the first phase of the prospective multicenter German DES.DE Registry).
The American journal of cardiology 20091115
-
Comparison of the efficacy and safety of zotarolimus-, sirolimus-, and paclitaxel-eluting stents in patients with ST-elevation myocardial infarction.
The American journal of cardiology 20091115
-
Rapamycin for refractory acute graft-versus-host disease.
Transplantation 20091115
-
[The effect of the different immunosuppression therapy on CD4(+)Foxp3(+) Treg cells in kidney recipients].
Zhonghua wai ke za zhi [Chinese journal of surgery] 20091115
-
Three-year outcomes after sirolimus-eluting stent implantation for unprotected left main coronary artery disease: insights from the j-Cypher registry.
Circulation 20091110
-
The 5-year clinical outcomes after a randomized comparison of sirolimus-eluting versus bare-metal stent implantation in patients with ST-segment elevation myocardial infarction.
Journal of the American College of Cardiology 20091110
-
Differential healing after sirolimus, paclitaxel, and bare metal stent placement in combination with peroxisome proliferator-activator receptor gamma agonists: requirement for mTOR/Akt2 in PPARgamma activation.
Circulation research 20091106
-
Conversion to sirolimus of patients with chronic allograft nephropathy--a retrospective analysis of outcome and influencing factors.
Langenbeck's archives of surgery 20091101
-
Therapeutic drug monitoring of everolimus using the dried blood spot method in combination with liquid chromatography-mass spectrometry.
Journal of pharmaceutical and biomedical analysis 20091101
-
Variations in the effects on synthesis of amyloid beta protein in modulated autophagic conditions.
Neurological research 20091101
-
Rapamycin prevents transforming growth factor-alpha-induced pulmonary fibrosis.
American journal of respiratory cell and molecular biology 20091101
-
Phase II trial of temsirolimus in patients with relapsed or refractory multiple myeloma.
Leukemia research 20091101
-
Safety and tolerability of sirolimus treatment in patients with autosomal dominant polycystic kidney disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091101
-
Gender-based evaluation of the XIENCE V everolimus-eluting coronary stent system: clinical and angiographic results from the SPIRIT III randomized trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091101
-
Response to imatinib plus sirolimus in advanced chordoma.
Annals of oncology : official journal of the European Society for Medical Oncology 20091101
-
Involvement of mTOR kinase in cytokine-dependent microglial activation and cell proliferation.
Biochemical pharmacology 20091101
-
Tumour flare during interruption of temsirolimus treatment for metastatic renal cell cancer.
Clinical oncology (Royal College of Radiologists (Great Britain)) 20091101
-
Randomized evaluation of two drug-eluting stents with identical metallic platform and biodegradable polymer but different agents (paclitaxel or sirolimus) compared against bare stents: 1-year results of the PAINT trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091101
-
Critical roles for the TSC-mTOR pathway in β-cell function.
American journal of physiology. Endocrinology and metabolism 20091101
-
Rapamycin selectively inhibits expression of an inducible keratin (K6a) in human keratinocytes and improves symptoms in pachyonychia congenita patients.
Journal of dermatological science 20091101
-
Predictors and prognosis of stent fracture after sirolimus-eluting stent implantation.
Circulation journal : official journal of the Japanese Circulation Society 20091101
-
Cryptosporidiosis in paediatric renal transplantation.
Pediatric nephrology (Berlin, Germany) 20091101
-
Spreading of mesothelioma cells is rapamycin-sensitive and requires continuing translation.
Journal of cellular biochemistry 20091101
-
Insulin resistance without elevated mammalian target of rapamycin complex 1 activity in muscles of mice fed a high-fat diet.
Journal of applied physiology (Bethesda, Md. : 1985) 20091101
-
Characterization of pneumonitis in patients with advanced non-small cell lung cancer treated with everolimus (RAD001).
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20091101
-
Distinct subsets of Sit4 holophosphatases are required for inhibition of Saccharomyces cerevisiae growth by rapamycin and zymocin.
Eukaryotic cell 20091101
-
Clinical outcomes of sirolimus-eluting stenting after rotational atherectomy.
Circulation journal : official journal of the Japanese Circulation Society 20091101
-
Development and validation of a semi-automated assay for the highly sensitive quantification of Biolimus A9 in human whole blood using high-performance liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091101
-
Morbus Crohn--a disease of failing macroautophagy in the immune system?
International immunology 20091101
-
Everolimus but not mycophenolate mofetil therapy is associated with soluble HLA-G expression in heart transplant patients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20091101
-
Sirolimus-eluting stent placement for refractory renal artery in-stent restenosis: sustained patency and clinical benefit at 24 months.
Vascular medicine (London, England) 20091101
-
The stent-eluting drugs sirolimus and paclitaxel suppress healing of the endothelium by induction of autophagy.
The American journal of pathology 20091101
-
Balancing needs and means: the dilemma of the beta-cell in the modern world.
Diabetes, obesity & metabolism 20091101
-
Downregulation of 18F-FDG uptake in PET as an early pharmacodynamic effect in treatment of non-small cell lung cancer with the mTOR inhibitor everolimus.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20091101
-
Interstitial fibrosis quantification in renal transplant recipients randomized to continue cyclosporine or convert to sirolimus.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20091101
-
A phase I study of the mammalian target of rapamycin inhibitor sirolimus and MEC chemotherapy in relapsed and refractory acute myelogenous leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 20091101
-
Transplantation: time to rethink immunosuppression by mTOR inhibitors?
Nature reviews. Nephrology 20091101
-
HOTLINE II, ISAR-TEST-4 trial, biodegradable stent coatings show promise.
European heart journal 20091101
-
Covered stent for the treatment of coronary aneurysm after sirolimus-eluting stent implantation in a patient with Takayasu's arteritis.
The Journal of invasive cardiology 20091101
-
Sirolimus therapy for patients with adult polycystic kidney disease: a pilot study.
Transplantation proceedings 20091101
-
Rapamycin as a therapy of choice after renal transplantation in a patient with tuberous sclerosis complex.
Transplantation proceedings 20091101
-
Usefulness of sirolimus as rescue therapy in heart transplant recipients with renal failure: analysis of the Spanish Multicenter Observational Study (RAPACOR).
Transplantation proceedings 20091101
-
[Conversion to rapamycin in liver transpant recipients with renal insufficiency].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20091101
-
Sirolimus: a novel immunosuppressive drug in heart transplantation.
Recent patents on cardiovascular drug discovery 20091101
-
Long-term risk of adverse outcomes and new malignancies in patients treated with oral sirolimus for prevention of restenosis.
JACC. Cardiovascular interventions 20091101
-
No association of chromosome 9p21.3 variation with clinical and angiographic outcomes after placement of drug-eluting stents.
JACC. Cardiovascular interventions 20091101
-
Comparison of long-term outcomes following sirolimus-eluting stent vs paclitaxel-eluting stent implantation in patients with long calcified coronary lesions.
Clinical cardiology 20091101
-
Cost analysis of sirolimus-eluting stents in the Japanese health insurance system.
International heart journal 20091101
-
Long-term effects of novel biodegradable, polymer-coated, sirolimus-eluting stents on neointimal formation in a porcine coronary model.
International heart journal 20091101
-
[Indications of mTOR inhibitors in liver transplantation].
Gastroenterologie clinique et biologique 20091101
-
Everolimus de novo in liver transplantation.
Gastroenterologie clinique et biologique 20091101
-
[Minimize kidney failure in transplantation patients with proliferation signal inhibitors].
Gastroenterologie clinique et biologique 20091101
-
[Liver transplantation for hepatocellular carcinoma and potential application of PSI].
Gastroenterologie clinique et biologique 20091101
-
[Antitumoral effect of proliferation signal inhibitors].
Gastroenterologie clinique et biologique 20091101
-
[Side effects of proliferation signal inhibitors and their management].
Gastroenterologie clinique et biologique 20091101
-
Impact of sirolimus-eluting stent implantation compared to bare-metal stent implantation for acute myocardial infarction on coronary plaque composition at nine months follow-up: a Virtual Histology intravascular ultrasound analysis. Results from the Leiden MISSION! intervention study.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091101
-
How should I treat a complex Post-CABG patient?
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091101
-
Prospective observational study of sirolimus as primary immunosuppression after renal transplantation.
Transplantation 20091027
-
Everolimus: in advanced renal cell carcinoma.
Drugs 20091022
-
Synergistic anti-cancer effects of immunotoxin and cyclosporin in vitro and in vivo.
British journal of cancer 20091020
-
Preparation and in vitro release profiles of drug-eluting controlled biodegradable polymer coating stents.
Colloids and surfaces. B, Biointerfaces 20091015
-
A novel PTEN-dependent link to ubiquitination controls FLIPS stability and TRAIL sensitivity in glioblastoma multiforme.
Cancer research 20091015
-
Gastric cancer: trastuzumab trial results spur search for other targets.
Journal of the National Cancer Institute 20091007
-
mTOR signaling in epileptogenesis: too much of a good thing?
The Journal of neuroscience : the official journal of the Society for Neuroscience 20091007
-
Recurrent acute myocardial infarction after 32 months: very late stent thrombosis after sirolimus-eluting stent implantation.
Chinese medical journal 20091005
-
Specification of neuronal polarity regulated by local translation of CRMP2 and Tau via the mTOR-p70S6K pathway.
The Journal of biological chemistry 20091002
-
Rapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability.
The Journal of biological chemistry 20091002
-
Cell signaling. Aging is RSKy business.
Science (New York, N.Y.) 20091002
-
Antitumoral activity of rapamycin mediated through inhibition of HIF-1alpha and VEGF in hepatocellular carcinoma.
Digestive diseases and sciences 20091001
-
Pathological finding of sirolimus-eluting stent (SES) restenosis lesion with black hole appearance on intravascular ultrasound.
Circulation journal : official journal of the Japanese Circulation Society 20091001
-
Activation of the mammalian target of rapamycin signalling pathway in prostate cancer and its association with patient clinicopathological characteristics.
BJU international 20091001
-
Inhibition of mammalian target of rapamycin (mTOR) signalling in C2C12 myoblasts prevents myogenic differentiation without affecting the hyperphosphorylation of 4E-BP1.
Cellular signalling 20091001
-
Distribution of angiographic measures of restenosis after drug-eluting stent implantation.
Heart (British Cardiac Society) 20091001
-
Growth failure associated with sirolimus: case report.
Pediatric nephrology (Berlin, Germany) 20091001
-
Rapamycin-treated mature dendritic cells have a unique cytokine secretion profile and impaired allostimulatory capacity.
Transplant international : official journal of the European Society for Organ Transplantation 20091001
-
Inhibition of mammalian target of rapamycin signaling potentiates the effects of all-trans retinoic acid to induce growth arrest and differentiation of human acute myelogenous leukemia cells.
International journal of cancer 20091001
-
Role of the novel mTOR inhibitor RAD001 (everolimus) in anaplastic thyroid cancer.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20091001
-
Efficacy of everolimus (RAD001) in patients with advanced NSCLC previously treated with chemotherapy alone or with chemotherapy and EGFR inhibitors.
Annals of oncology : official journal of the European Society for Medical Oncology 20091001
-
Targeting the mammalian target of Rapamycin to inhibit VEGF and cytokines for the treatment of primary effusion lymphoma.
Leukemia 20091001
-
Multi-site analytical evaluation of a chemiluminescent magnetic microparticle immunoassay (CMIA) for sirolimus on the Abbott ARCHITECT analyzer.
Clinical biochemistry 20091001
-
Effective treatment of advanced colorectal cancer by rapamycin and 5-FU/oxaliplatin monitored by TIMP-1.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20091001
-
Mammalian target of rapamycin is activated in association with myometrial proliferation during pregnancy.
Endocrinology 20091001
-
Mechanical properties, drug eluting characteristics and in vivo performance of a genipin-crosslinked chitosan polymeric stent.
Biomaterials 20091001
-
Signal transducer and activator of transcription 3 is required for abnormal proliferation and survival of TSC2-deficient cells: relevance to pulmonary lymphangioleiomyomatosis.
Molecular pharmacology 20091001
-
Increased mycophenolic acid exposure in stable kidney transplant recipients on tacrolimus as compared with those on sirolimus: implications for pharmacokinetics.
Clinical pharmacology and therapeutics 20091001
-
Effects of prostaglandin D2 on Na-dependent phosphate transport activity and its intracellular signaling mechanism in osteoblast-like cells.
Prostaglandins, leukotrienes, and essential fatty acids 20091001
-
Lipopolysaccharide directly alters renal tubule transport through distinct TLR4-dependent pathways in basolateral and apical membranes.
American journal of physiology. Renal physiology 20091001
-
The short-term effect on restenosis and thrombosis of a cobalt-chromium stent eluting two drugs in a porcine coronary artery model.
Journal of interventional cardiology 20091001
-
Targeted epidermal growth factor receptor nanoparticle bioconjugates for breast cancer therapy.
Biomaterials 20091001
-
Inhibition of mTOR attenuates store-operated Ca2+ entry in cells from endarterectomized tissues of patients with chronic thromboembolic pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology 20091001
-
AMP-activated protein kinase enhances the expression of muscle-specific ubiquitin ligases despite its activation of IGF-1/Akt signaling in C2C12 myotubes.
Journal of cellular biochemistry 20091001
-
Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2.
Blood 20091001
-
Identification of novel autophagy regulators by a luciferase-based assay for the kinetics of autophagic flux.
Autophagy 20091001
-
Cyclosporine and sirolimus pharmacokinetics and drug-to-drug interactions in kidney transplant recipients.
Fundamental & clinical pharmacology 20091001
-
Rosiglitazone prevents sirolimus-induced hypomagnesemia, hypokalemia, and downregulation of NKCC2 protein expression.
American journal of physiology. Renal physiology 20091001
-
Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivo.
Journal of hepatology 20091001
-
Immunosuppressive drugs and Tregs: a critical evaluation!
Clinical journal of the American Society of Nephrology : CJASN 20091001
-
Expression and mechanism of mammalian target of rapamycin in age-related renal cell senescence and organ aging.
Mechanisms of ageing and development 20091001
-
Long-term clinical outcomes and stent thrombosis of sirolimus-eluting versus bare metal stents in patients with end-stage renal disease: results of Korean multicenter angioplasty team (KOMATE) Registry.
Journal of interventional cardiology 20091001
-
Significant association of coronary artery calcification in stent delivery route with restenosis after sirolimus-eluting stent implantation.
Circulation journal : official journal of the Japanese Circulation Society 20091001
-
Percutaneous treatment with drug-eluting stent vs bypass surgery in patients suffering from chronic stable angina with multivessel disease involving significant proximal stenosis in left anterior descending artery.
Circulation journal : official journal of the Japanese Circulation Society 20091001
-
Randomized, non-inferiority trial of three limus agent-eluting stents with different polymer coatings: the Intracoronary Stenting and Angiographic Results: Test Efficacy of 3 Limus-Eluting Stents (ISAR-TEST-4) Trial.
European heart journal 20091001
-
Sirolimus-containing graft-versus-host disease prophylaxis in patients with lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091001
-
Dual inhibition of mitogen-activated protein kinase kinase and mammalian target of rapamycin in differentiated and anaplastic thyroid cancer.
The Journal of clinical endocrinology and metabolism 20091001
-
Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility.
International journal of oncology 20091001
-
Red blood cells carry out T cell growth and survival bioactivities that are sensitive to cyclosporine A.
Cellular and molecular life sciences : CMLS 20091001
-
Focal brain malformations: seizures, signaling, sequencing.
Epilepsia 20091001
-
Animal models of focal cortical dysplasia and tuberous sclerosis complex: recent progress toward clinical applications.
Epilepsia 20091001
-
Combined Bcl-2/mammalian target of rapamycin inhibition leads to enhanced radiosensitization via induction of apoptosis and autophagy in non-small cell lung tumor xenograft model.
Clinical cancer research : an official journal of the American Association for Cancer Research 20091001
-
MYC activity mitigates response to rapamycin in prostate cancer through eukaryotic initiation factor 4E-binding protein 1-mediated inhibition of autophagy.
Cancer research 20091001
-
Benefits of drug-eluting stents as compared to bare metal stent in ST-segment elevation myocardial infarction: four year results of the PaclitAxel or Sirolimus-Eluting stent vs bare metal stent in primary angiOplasty (PASEO) randomized trial.
American heart journal 20091001
-
SPIRIT IV trial design: a large-scale randomized comparison of everolimus-eluting stents and paclitaxel-eluting stents in patients with coronary artery disease.
American heart journal 20091001
-
Significantly lower incidence of early definite stent thrombosis of drug-eluting stents after unrestricted use in Japan using ticlopidine compared to western countries using clopidogrel: a retrospective comparison with western mega-studies.
Journal of cardiology 20091001
-
A combined, rational approach towards inhibition of the MEK-ERK and mTOR pathways in pancreatic ductal adenocarcinoma: promise or deja vu?
Cancer biology & therapy 20091001
-
Regulation by FK506 and rapamycin of Ca2+ release from the sarcoplasmic reticulum in vascular smooth muscle: the role of FK506 binding proteins and mTOR.
British journal of pharmacology 20091001
-
The insulin-like growth factor-1 receptor-targeting antibody, CP-751,871, suppresses tumor-derived VEGF and synergizes with rapamycin in models of childhood sarcoma.
Cancer research 20091001
-
Conversion from a calcineurin inhibitor to everolimus therapy in maintenance liver transplant recipients: a prospective, randomized, multicenter trial.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20091001
-
Rapamycin inhibits hepatic fibrosis in rats by attenuating multiple profibrogenic pathways.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20091001
-
Long-term safety and efficacy of sirolimus-eluting stents in Japanese patients: a single-center cohort study.
The Journal of invasive cardiology 20091001
-
Rotational atherectomy is useful to treat restenosis lesions due to crushing of a sirolimus-eluting stent implanted in severely calcified lesions: experimental study and initial clinical experience.
The Journal of invasive cardiology 20091001
-
Pentagalloylglucose induces autophagy and caspase-independent programmed deaths in human PC-3 and mouse TRAMP-C2 prostate cancer cells.
Molecular cancer therapeutics 20091001
-
Relationship between expression of mutant type glutathione S-transferase theta-1 gene and reactivity of rapamycin in myelodysplastic syndrome.
Hematology (Amsterdam, Netherlands) 20091001
-
Clinical and angiographic outcomes in diabetics from the ENDEAVOR IV trial: randomized comparison of zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease.
JACC. Cardiovascular interventions 20091001
-
Clinical and angiographic results with the next-generation resolute stent system: a prospective, multicenter, first-in-human trial.
JACC. Cardiovascular interventions 20091001
-
A generation 2.5 drug-eluting stent?
JACC. Cardiovascular interventions 20091001
-
Optimal stent-sizing with intravascular ultrasound contributes to complete neointimal coverage after sirolimus-eluting stent implantation assessed by angioscopy.
JACC. Cardiovascular interventions 20091001
-
Optimal stent expansion and complete neointimal coverage: does this association make sense?
JACC. Cardiovascular interventions 20091001
-
Current approaches to the use of sirolimus in renal transplantation.
Transplantation proceedings 20091001
-
Conversion from calcineurin inhibitors to sirolimus in kidney transplant recipients: a retrospective cohort study.
Transplantation proceedings 20091001
-
Human mesenchymal stem cells and immunosuppressive drug interactions in allogeneic responses: an in vitro study using human cells.
Transplantation proceedings 20091001
-
[Recent progress in the diagnosis and treatment of aplastic anemia in children].
[Rinsho ketsueki] The Japanese journal of clinical hematology 20091001
-
[The role of intracellular signal pathway of mTOR/S6 in CD3+ T lymphocytes of refractory/relapsed aplastic anemia patients].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20091001
-
Effects of combined inhibition of MEK and mTOR on downstream signaling and tumor growth in pancreatic cancer xenograft models.
Cancer biology & therapy 20091001
-
Treatment of acute myocardial infarction with sirolimus-eluting stents results in chronic endothelial dysfunction in the infarct-related coronary artery.
Circulation. Cardiovascular interventions 20091001
-
Frontline therapy in mantle cell lymphoma: the role of high-dose therapy and integration of new agents.
Current hematologic malignancy reports 20091001
-
DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212.
Neuron 20090924
-
Pore-filling nanoporous templates from degradable block copolymers for nanoscale drug delivery.
ACS nano 20090922
-
Randomized phase II study comparing two schedules of everolimus in patients with recurrent/metastatic breast cancer: NCIC Clinical Trials Group IND.163.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090920
-
Triple antiplatelet therapy for clopidogrel resistance with stent malapposition: a case report.
Chinese medical journal 20090920
-
Genetic alterations in the phosphoinositide 3-kinase/Akt signaling pathway confer sensitivity of thyroid cancer cells to therapeutic targeting of Akt and mammalian target of rapamycin.
Cancer research 20090915
-
Long-Term outcome of drug-eluting stents compared with bare metal stents in ST-segment elevation myocardial infarction: results of the paclitaxel- or sirolimus-eluting stent versus bare metal stent in Primary Angioplasty (PASEO) Randomized Trial.
Circulation 20090915
-
Renal cell carcinoma with an emphasis on drug therapy of advanced disease, part 2.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090915
-
mTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells.
Cancer research 20090915
-
Inhibition of tumor growth progression by antiandrogens and mTOR inhibitor in a Pten-deficient mouse model of prostate cancer.
Cancer research 20090915
-
Mammalian target of rapamycin inhibition prevents glomerular hypertrophy in a model of renal mass reduction.
Transplantation 20090915
-
Outcomes with conversion from calcineurin inhibitors to sirolimus after renal transplantation in the context of steroid withdrawal or steroid continuation.
Transplantation 20090915
-
[Effects of Rapamycin on angiogenesis and tumor progression in human hepatocellular carcinoma implantation mice].
Zhonghua wai ke za zhi [Chinese journal of surgery] 20090915
-
Sirolimus, bevacizumab, 5-Fluorouracil and irinotecan for advanced colorectal cancer: a pilot study.
World journal of gastroenterology 20090914
-
Impact of drug-eluting stent selection on long-term clinical outcomes in patients treated for unprotected left main coronary artery disease: the sirolimus vs paclitaxel drug-eluting stent for left main registry (SP-DELFT).
International journal of cardiology 20090911
-
The Vam6 GEF controls TORC1 by activating the EGO complex.
Molecular cell 20090911
-
Mutation of a phosphorylatable residue in Put3p affects the magnitude of rapamycin-induced PUT1 activation in a Gat1p-dependent manner.
The Journal of biological chemistry 20090904
-
mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging.
Cell stem cell 20090904
-
Ribavirin enhances interferon signaling via stimulation of mTOR and p53 activities.
FEBS letters 20090903
-
Silent very late thrombotic occlusion of sirolimus-eluting stent confirmed by directional coronary atherectomy.
Circulation journal : official journal of the Japanese Circulation Society 20090901
-
Effective inhibition of xenografts of hepatocellular carcinoma (HepG2) by rapamycin and bevacizumab in an intrahepatic model.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20090901
-
The effect of rapamycin on bone growth in rabbits.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20090901
-
Calcineurin inhibitor minimization in pediatric liver allograft recipients.
Pediatric transplantation 20090901
-
Novel and evolving therapies in the treatment of malignant phaeochromocytoma: experience with the mTOR inhibitor everolimus (RAD001).
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090901
-
Everolimus restores gefitinib sensitivity in resistant non-small cell lung cancer cell lines.
Biochemical pharmacology 20090901
-
Molecular mechanisms of pancreatic dysfunction induced by protein malnutrition.
Gastroenterology 20090901
-
Oral rapamycin reduces tumour burden and vascularization in Lkb1(+/-) mice.
The Journal of pathology 20090901
-
Monotherapy rapamycin allows an increase of CD4 CD25 FoxP3 T cells in renal recipients.
Transplant international : official journal of the European Society for Organ Transplantation 20090901
-
S6 kinase 1 knockout inhibits uninephrectomy- or diabetes-induced renal hypertrophy.
American journal of physiology. Renal physiology 20090901
-
Synergistic effect of rapamycin and cisplatin in endometrial cancer cells.
Cancer 20090901
-
Sirolimus-related dyspnoea, airway obstruction and pleural effusion after lung transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20090901
-
Long-term administration of rapamycin reduces adiposity, but impairs glucose tolerance in high-fat diet-fed KK/HlJ mice.
Basic & clinical pharmacology & toxicology 20090901
-
Calcineurin-mediated GABA(A) receptor dephosphorylation in rats after kainic acid-induced status epilepticus.
Seizure 20090901
-
Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer.
Gastroenterology 20090901
-
Twenty-four months clinical outcomes of sirolimus-eluting stents for the treatment of small coronary arteries: the long-term SES-SMART clinical study.
European heart journal 20090901
-
Mammalian target of rapamycin inhibitors rapamycin and RAD001 (everolimus) induce anti-proliferative effects in GH-secreting pituitary tumor cells in vitro.
Endocrine-related cancer 20090901
-
Inhibition of PKHD1 may cause S-phase entry via mTOR signaling pathway.
Cell biology international 20090901
-
Management of sorafenib, sunitinib, and temsirolimus toxicity in metastatic renal cell carcinoma.
Current opinion in supportive and palliative care 20090901
-
Rapamycin inhibits hepatectomy-induced stimulation of metastatic tumor growth by reduction of angiogenesis, microvascular blood perfusion, and tumor cell proliferation.
Annals of surgical oncology 20090901
-
An imbalance in Akt/mTOR is involved in the apoptotic and acantholytic processes in a mouse model of pemphigus vulgaris.
Experimental dermatology 20090901
-
Successful control of intractable hypoglycemia using rapamycin in an 86-year-old man with a pancreatic insulin-secreting islet cell tumor and metastases.
The Journal of clinical endocrinology and metabolism 20090901
-
The growing importance of mTORC1-S6K1 signaling in kidney.
American journal of physiology. Renal physiology 20090901
-
Rapamycin by itself and additively in combination with carboplatin inhibits the growth of ovarian cancer cells.
Gynecologic oncology 20090901
-
Prophylactic immune tolerance induced by changing the ratio of antigen-specific effector to regulatory T cells.
Journal of thrombosis and haemostasis : JTH 20090901
-
Rapamycin, the mTOR kinase inhibitor, sensitizes acute myeloid leukemia cells, HL-60 cells, to the cytotoxic effect of arabinozide cytarabine.
Anti-cancer drugs 20090901
-
Randomised trial of three rapamycin-eluting stents with different coating strategies for the reduction of coronary restenosis: 2-year follow-up results.
Heart (British Cardiac Society) 20090901
-
A small GTPase, human Rab32, is required for the formation of autophagic vacuoles under basal conditions.
Cellular and molecular life sciences : CMLS 20090901
-
Quantification of nuclear protein transport using induced heterodimerization.
Traffic (Copenhagen, Denmark) 20090901
-
Infrapopliteal application of sirolimus-eluting versus bare metal stents for critical limb ischemia: analysis of long-term angiographic and clinical outcome.
Journal of vascular and interventional radiology : JVIR 20090901
-
Three-year prognosis of Japanese patients with ST-elevation myocardial infarction treated with sirolimus-eluting stents.
Coronary artery disease 20090901
-
Posttransplantation hypomagnesemia and its relation with immunosuppression as predictors of new-onset diabetes after transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090901
-
Influence of sirolimus on cyclosporine-induced pancreas islet dysfunction in rats.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090901
-
Treatment with rapamycin ameliorates clinical and histological signs of protracted relapsing experimental allergic encephalomyelitis in Dark Agouti rats and induces expansion of peripheral CD4+CD25+Foxp3+ regulatory T cells.
Journal of autoimmunity 20090901
-
Rapamycin enhances platelet aggregation induced by adenosine diphosphate in vitro.
Platelets 20090901
-
Systematic gene expression profile of hypothalamus in calorie-restricted mice implicates the involvement of mTOR signaling in neuroprotective activity.
Mechanisms of ageing and development 20090901
-
Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling.
Nature neuroscience 20090901
-
CCR5 blockade in combination with rapamycin prolongs cardiac allograft survival in mice.
Clinical and experimental immunology 20090901
-
Advanced neointimal growth is not associated with a low risk of in-stent thrombus. Optical coherence tomographic findings after first-generation drug-eluting stent implantation.
Circulation journal : official journal of the Japanese Circulation Society 20090901
-
CD137 ligand-mediated reverse signals increase cell viability and cytokine expression in murine myeloid cells: involvement of mTOR/p70S6 kinase and Akt.
European journal of immunology 20090901
-
Increasing longevity through caloric restriction or rapamycin feeding in mammals: common mechanisms for common outcomes?
Aging cell 20090901
-
Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss.
Nature neuroscience 20090901
-
mTOR is a promising therapeutic target both in cisplatin-sensitive and cisplatin-resistant clear cell carcinoma of the ovary.
Clinical cancer research : an official journal of the American Association for Cancer Research 20090901
-
Insulin-like growth factor-1 receptor inhibition induces a resistance mechanism via the epidermal growth factor receptor/HER3/AKT signaling pathway: rational basis for cotargeting insulin-like growth factor-1 receptor and epidermal growth factor receptor in hepatocellular carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20090901
-
Concurrent and sequential administration of chemotherapy and the Mammalian target of rapamycin inhibitor temsirolimus in human cancer cells and xenografts.
Clinical cancer research : an official journal of the American Association for Cancer Research 20090901
-
5-year clinical outcomes after sirolimus-eluting stent implantation insights from a patient-level pooled analysis of 4 randomized trials comparing sirolimus-eluting stents with bare-metal stents.
Journal of the American College of Cardiology 20090901
-
Rapamycin--rather than FK506--might promote allograft tolerance induced by CD4+CD25+ regulatory T cells.
Surgery 20090901
-
Images in cardiovascular medicine: Late abnormal vessel wall reaction 3 years after sirolimus-eluting stent implantation.
Circulation 20090901
-
Very late stent thrombosis of sirolimus-eluting stent combined with late stent malapposition and aneurysm formation.
The Journal of invasive cardiology 20090901
-
Long-term follow-up after drug eluting stent implantation in left main trifurcations.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090901
-
Bifurcation stenting with drug-eluting stents: a systematic review and meta-analysis of randomised trials.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090901
-
Scanning electron microscopic assessment of the biodegradable coating on expanded biolimus-eluting stents.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090901
-
Proliferation signal inhibitors for the treatment of refractory autoimmune rheumatic diseases: a new therapeutic option.
Annals of the New York Academy of Sciences 20090901
-
Early sirolimus therapy in renal transplant recipients at high risk: is it justified?
Transplantation proceedings 20090901
-
Conversion to sirolimus for chronic allograft nephropathy and calcineurin inhibitor toxicity and the adverse effects of sirolimus after conversion.
Transplantation proceedings 20090901
-
Impact of vessel size on angiographic and clinical outcomes of revascularization with biolimus-eluting stent with biodegradable polymer and sirolimus-eluting stent with durable polymer the LEADERS trial substudy.
JACC. Cardiovascular interventions 20090901
-
Effect of balloon inflation time on expansion of sirolimus-eluting stent.
Heart and vessels 20090901
-
Resolution of late sirolimus-eluting stent thrombosis after tirofiban treatment.
Heart and vessels 20090901
-
[Bemusement and strategy on the efficacy of clinical application of targeted anticancer drugs].
Zhonghua zhong liu za zhi [Chinese journal of oncology] 20090901
-
[Effect of signal transduction inhibitors on human endometrial carcinoma cells with differential PTEN gene expression].
Zhonghua fu chan ke za zhi 20090901
-
[Clinical study of application of sirolimus with dose-reduced or discontinued cyclosporine A for prevention of acute rejection after kidney transplantation].
Zhonghua wai ke za zhi [Chinese journal of surgery] 20090901
-
Cell signaling. Blocking Akt-ivity.
Science (New York, N.Y.) 20090828
-
Indirect antitumor effects of mammalian target of rapamycin inhibitors against Kaposi sarcoma in transplant patients.
Transplantation 20090827
-
Long-term clinical outcomes of sirolimus- versus paclitaxel-eluting stents for patients with unprotected left main coronary artery disease: analysis of the MAIN-COMPARE (revascularization for unprotected left main coronary artery stenosis: comparison of percutaneous coronary angioplasty versus surgical revascularization) registry.
Journal of the American College of Cardiology 20090825
-
Letter by Movahed regarding article, 'Randomized Study of the Crush Technique Versus Provisional Side-Branch Stenting in True Coronary Bifurcations: The CACTUS (Coronary Bifurcations: Application of the Crushing Technique Using Sirolimus-Eluting Stents) Study'.
Circulation 20090825
-
Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia.
Blood 20090820
-
Sirolimus-eluting stent treatment at high-volume centers confers lower mortality at 6-month follow-up: results from the prospective multicenter German Cypher Registry.
Circulation 20090818
-
Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells.
Autophagy 20090816
-
Targeted inhibition of mammalian target of rapamycin for the treatment of advanced renal cell carcinoma.
Cancer 20090815
-
Analysis of PTEN and HIF-1alpha and correlation with efficacy in patients with advanced renal cell carcinoma treated with temsirolimus versus interferon-alpha.
Cancer 20090815
-
Pirfenidone inhibits T-cell activation, proliferation, cytokine and chemokine production, and host alloresponses.
Transplantation 20090815
-
Minimization of maintenance immunosuppression early after renal transplantation: an interim analysis.
Transplantation 20090815
-
Increased interleukin-10 production without expansion of CD4+CD25+ T-regulatory cells in early stable renal transplant patients on calcineurin inhibitors.
Transplantation 20090815
-
Is the intracellular ATP concentration of CD4+ T-Cells a predictive biomarker of immune status in stable transplant recipients?
Transplantation 20090815
-
Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.
Genes & development 20090815
-
A Rab escort protein integrates the secretion system with TOR signaling and ribosome biogenesis.
Genes & development 20090815
-
Opposing role of condensin and radiation-sensitive gene RAD52 in ribosomal DNA stability regulation.
The Journal of biological chemistry 20090814
-
Rapamycin inhibits poly(ADP-ribosyl)ation in intact cells.
Biochemical and biophysical research communications 20090814
-
Phase III study to evaluate temsirolimus compared with investigator's choice therapy for the treatment of relapsed or refractory mantle cell lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090810
-
The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis.
Proceedings of the National Academy of Sciences of the United States of America 20090804
-
Use of a novel anti-proliferative compound coated on a biopolymer to mitigate platelet-derived growth factor-induced proliferation in human aortic smooth muscle cells: comparison with sirolimus.
Glycoconjugate journal 20090801
-
Participation of mammalian target of rapamycin complex 1 in Toll-like receptor 2- and 4-induced neutrophil activation and acute lung injury.
American journal of respiratory cell and molecular biology 20090801
-
Short and long-term benefits of sirolimus-eluting stent in ST-segment elevation myocardial infarction: a meta-analysis of randomized trials.
Journal of thrombosis and thrombolysis 20090801
-
Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma.
Journal of cellular and molecular medicine 20090801
-
Rapamycin for focal segmental glomerulosclerosis: a report of 3 cases.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20090801
-
Long-term rapamycin therapy in the Han:SPRD rat model of polycystic kidney disease (PKD).
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090801
-
Clinical impact of sirolimus-eluting stent in ST-segment elevation myocardial infarction: a meta-analysis of randomized clinical trials.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090801
-
Therapeutic role of sirolimus in non-transplant kidney disease.
Pharmacology & therapeutics 20090801
-
Everolimus, a promising medical therapy for coronary heart disease?
Medical hypotheses 20090801
-
Clinical and angiographic outcomes following percutaneous coronary intervention with sirolimus-eluting stents versus bare-metal stents in hemodialysis patients.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20090801
-
Gastric mammalian target of rapamycin signaling regulates ghrelin production and food intake.
Endocrinology 20090801
-
The role of MTOR in mouse uterus during embryo implantation.
Reproduction (Cambridge, England) 20090801
-
Rapamycin inhibition of the Akt/mTOR pathway blocks select stages of VEGF-A164-driven angiogenesis, in part by blocking S6Kinase.
Arteriosclerosis, thrombosis, and vascular biology 20090801
-
In vitro interactions between antifungals and immunosuppressive drugs against zygomycetes.
Antimicrobial agents and chemotherapy 20090801
-
Autophagy is required for extension of yeast chronological life span by rapamycin.
Autophagy 20090801
-
Effect of rapamycin on cue-induced drug craving in abstinent heroin addicts.
European journal of pharmacology 20090801
-
Testosterone induces cardiomyocyte hypertrophy through mammalian target of rapamycin complex 1 pathway.
The Journal of endocrinology 20090801
-
Rapamycin prevents concanavalin A-induced liver injury by inhibiting lymphocyte activation.
Journal of gastroenterology and hepatology 20090801
-
Clinical grade preparation of human natural regulatory T-cells encoding the thymidine kinase suicide gene as a safety gene: authors' reponse.
The journal of gene medicine 20090801
-
Posttransplant anemia: the role of sirolimus.
Kidney international 20090801
-
Infusion of mesenchymal stem cells and rapamycin synergize to attenuate alloimmune responses and promote cardiac allograft tolerance.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090801
-
Performance of the new mycophenolate assay based on IMPDH enzymatic activity for pharmacokinetic investigations and setup of Bayesian estimators in different populations of allograft recipients.
Therapeutic drug monitoring 20090801
-
Biochemical, cellular, and in vivo activity of novel ATP-competitive and selective inhibitors of the mammalian target of rapamycin.
Cancer research 20090801
-
Enhanced interaction between Hsp90 and raptor regulates mTOR signaling upon T cell activation.
Molecular immunology 20090801
-
Quiz page August 2009: Respiratory distress 5 years after kidney transplantation.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20090801
-
Are drug-eluting stents safe?: Definitely! Or probably... possibly? Or maybe not yet...
Clinical pharmacology and therapeutics 20090801
-
A spontaneous acinar cell carcinoma model for monitoring progression of pancreatic lesions and response to treatment through noninvasive bioluminescence imaging.
Clinical cancer research : an official journal of the American Association for Cancer Research 20090801
-
Comparison of radiosensitizing effects of the mammalian target of rapamycin inhibitor CCI-779 to cisplatin in experimental models of head and neck squamous cell carcinoma.
Molecular cancer therapeutics 20090801
-
A fractured sirolimus-eluting stent with a coronary aneurysm.
The Annals of thoracic surgery 20090801
-
Mid-term angiographic benefit of sirolimus-eluting stents compared with paclitaxel-eluting stents in patients with acute myocardial infarction.
Journal of cardiology 20090801
-
Coronary aneurysm associated with coronary perforation after sirolimus-eluting stents implantation: close follow-up exceeding 2 years by coronary 3-dimensional computed tomography.
Journal of cardiology 20090801
-
A case of a newly developed yellow neointima at stent implanted site 1 year after sirolimus-eluting stent placement: angioscopic findings.
Journal of cardiology 20090801
-
Rapamycin delays tumor development in murine livers by inhibiting proliferation of hepatocytes with DNA damage.
Hepatology (Baltimore, Md.) 20090801
-
SES for AMI: moving in the right direction.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090801
-
Black hole phenomenon observed on IVUS after late restenosis following sirolimus-eluting stent implantation.
The Journal of invasive cardiology 20090801
-
The effects of sirolimus on urothelial lesions chemically induced in ICR mice by BBN.
Anticancer research 20090801
-
[Effects of rapamycin on prostate cancer PC-3 cells].
Ai zheng = Aizheng = Chinese journal of cancer 20090801
-
Incomplete stent apposition after coronary stent implantation: myth or reality?
Journal of interventional cardiology 20090801
-
Predictive factors of re-restenosis after repeated sirolimus-eluting stent implantation for SES restenosis and clinical outcomes after percutaneous coronary intervention for SES restenosis.
Journal of interventional cardiology 20090801
-
Eosinophilic rash secondary to temsirolimus.
Clinical genitourinary cancer 20090801
-
In-hospital and 1-year outcomes among unselected percutaneous coronary intervention patients treated with either sirolimus- or paclitaxel-eluting stents: results from the EVENT (Evaluation of Drug Eluting Stents and Ischemic Events) registry.
JACC. Cardiovascular interventions 20090801
-
Angiographic restenosis and clinical recurrence after sirolimus- and paclitaxel-eluting stent implantation.
JACC. Cardiovascular interventions 20090801
-
Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease.
JACC. Cardiovascular interventions 20090801
-
Stent expansion at the segment with thrombus.
JACC. Cardiovascular interventions 20090801
-
[Effect of rapamycin on leukemia cell lines].
Zhongguo shi yan xue ye xue za zhi 20090801
-
Effect of coadministered HIV-protease inhibitors on tacrolimus and sirolimus blood concentrations in a kidney transplant recipient.
Fundamental & clinical pharmacology 20090801
-
Live fast, die young: new lessons in mammalian longevity.
Rejuvenation research 20090801
-
Biolimus-eluting biodegradable polymer versus sirolimus-eluting permanent polymer stent performance in long lesions: results from the LEADERS multicentre trial substudy.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090801
-
Angiographic and intravascular ultrasound findings following implantation of the Endeavor zotarolimus-eluting stents in patients from the real-world clinical practice.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090801
-
Immunosuppressants: JC virus encephalopathy. Rare but fatal.
Prescrire international 20090801
-
Novel role for the Saccharomyces cerevisiae oligopeptide transporter Opt2 in drug detoxification.
Biochemistry and cell biology = Biochimie et biologie cellulaire 20090801
-
[Bronchiolitis obliterans with organizing pneumonia associated with sirolimus in a patient after liver transplantation].
Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20090801
-
Comparison of temsirolimus pharmacokinetics in patients with renal cell carcinoma not receiving dialysis and those receiving hemodialysis: a case series.
Clinical therapeutics 20090801
-
Two-year clinical, angiographic, and intravascular ultrasound follow-up of the XIENCE V everolimus-eluting stent in the treatment of patients with de novo native coronary artery lesions: the SPIRIT II trial.
Circulation. Cardiovascular interventions 20090801
-
Contrast enhanced sonography shows superior microvascular renal allograft perfusion in patients switched from cyclosporine A to everolimus.
Transplantation 20090727
-
The use of intra-coronary optical coherence tomography for the assessment of sirolimus-eluting stent fracture.
International journal of cardiology 20090724
-
Infectious tolerance via the consumption of essential amino acids and mTOR signaling.
Proceedings of the National Academy of Sciences of the United States of America 20090721
-
Extracellular matrix binding mixed micelles for drug delivery applications.
Journal of controlled release : official journal of the Controlled Release Society 20090720
-
Different edge effects of paclitaxel- and sirolimus-eluting stents on proximal and distal edges in patients with unstable angina: serial intravascular ultrasound analysis.
Chinese medical journal 20090720
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
Nature 20090716
-
Ageing: A midlife longevity drug?
Nature 20090716
-
Comparison of rapamycin- and paclitaxel-eluting stents in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction.
The American journal of cardiology 20090715
-
Incidence of delayed graft function and wound healing complications after deceased-donor kidney transplantation is not affected by de novo everolimus.
Transplantation 20090715
-
Everolimus with reduced cyclosporine versus MMF with standard cyclosporine in de novo heart transplant recipients.
Transplantation 20090715
-
Comparison of inflammatory response after implantation of sirolimus- and paclitaxel-eluting stents in porcine coronary arteries.
Circulation 20090714
-
The everolimus-eluting stent in real-world patients: 6-month follow-up of the X-SEARCH (Xience V Stent Evaluated at Rotterdam Cardiac Hospital) registry.
Journal of the American College of Cardiology 20090714
-
The mTOR pathway is highly activated in diabetic nephropathy and rapamycin has a strong therapeutic potential.
Biochemical and biophysical research communications 20090710
-
Sirolimus can reverse resistance to gemcitabine, capecitabine and docetaxel combination therapy in pancreatic cancer.
JOP : Journal of the pancreas 20090706
-
mTOR regulates memory CD8 T-cell differentiation.
Nature 20090702
-
Immunology: A metabolic switch to memory.
Nature 20090702
-
RAD001 (everolimus) inhibits tumour growth in xenograft models of human hepatocellular carcinoma.
Journal of cellular and molecular medicine 20090701
-
Disposition of desipramine, a sensitive cytochrome P450 2D6 substrate, when coadministered with intravenous temsirolimus.
Cancer chemotherapy and pharmacology 20090701
-
Phospho-mTOR and phospho-4EBP1 in endometrial adenocarcinoma: association with stage and grade in vivo and link with response to rapamycin treatment in vitro.
Journal of cancer research and clinical oncology 20090701
-
Rapamycin-induced proteinuria following allogeneic hematopoietic stem cell transplantation.
Bone marrow transplantation 20090701
-
Amniotic membrane transplantation induces apoptosis in T lymphocytes in murine corneas with experimental herpetic stromal keratitis.
Investigative ophthalmology & visual science 20090701
-
Microarray analyses of the effects of NF-kappaB or PI3K pathway inhibitors on the LPS-induced gene expression profile in RAW264.7 cells: synergistic effects of rapamycin on LPS-induced MMP9-overexpression.
Cellular signalling 20090701
-
Performance characteristics of a no-pretreatment, random access sirolimus assay for the Dimension RxL clinical chemistry system.
Clinical biochemistry 20090701
-
Sirolimus-eluting stents, bare metal stents or coronary artery bypass grafting for patients with multivessel disease including involvement of the proximal left anterior descending artery: analysis of the Arterial Revascularization Therapies study part 2 (ARTS-II).
Heart (British Cardiac Society) 20090701
-
A novel role for the Drosophila epsin (lqf): involvement in autophagy.
Autophagy 20090701
-
An insight into the mechanistic role of p53-mediated autophagy induction in response to proteasomal inhibition-induced neurotoxicity.
Autophagy 20090701
-
The pharmacokinetics of mycophenolate mofetil in renal transplant recipients receiving standard-dose or low-dose cyclosporine, low-dose tacrolimus or low-dose sirolimus: the Symphony pharmacokinetic substudy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090701
-
Long-term clinical and angiographic outcomes after implantation of sirolimus-eluting stents with a 'modified mini-crush' technique in coronary bifurcation lesions.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090701
-
The incidence and predictors of postprocedural incomplete stent apposition after angiographically successful drug-eluting stent implantation.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090701
-
RAD001 (Everolimus) induces autophagy in acute lymphoblastic leukemia.
Autophagy 20090701
-
Practical recommendations for the early use of m-TOR inhibitors (sirolimus) in renal transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20090701
-
Optimal management of metastatic renal cell carcinoma: an algorithm for treatment.
BJU international 20090701
-
Rapamycin inhibits mTORC1, but not completely.
Autophagy 20090701
-
Improved long-term prognosis of elderly women in the era of sirolimus-eluting stents.
Circulation journal : official journal of the Japanese Circulation Society 20090701
-
Regulation and function of proline oxidase under nutrient stress.
Journal of cellular biochemistry 20090701
-
Late progression of renal pathology and cyst enlargement is reduced by rapamycin in a mouse model of nephronophthisis.
Kidney international 20090701
-
Rapamycin enhances LPS induction of tissue factor and tumor necrosis factor-alpha expression in macrophages by reducing IL-10 expression.
Molecular immunology 20090701
-
FK506 and rapamycin neuroprotect erection and involve different immunophilins in a rat model of cavernous nerve injury.
The journal of sexual medicine 20090701
-
The impact of everolimus versus mycophenolate on blood and lymphocyte cyclosporine exposure in heart-transplant recipients.
European journal of clinical pharmacology 20090701
-
Limited sampling strategies for the estimation of sirolimus daily exposure in kidney transplant recipients on a calcineurin inhibitor-free regimen.
Journal of clinical pharmacology 20090701
-
Rapamycin enhances aplaviroc anti-HIV activity: implications for the clinical development of novel CCR5 antagonists.
Antiviral research 20090701
-
Effect of autophagy on multiple myeloma cell viability.
Molecular cancer therapeutics 20090701
-
Considerations in sirolimus use in the early and late post-transplant periods.
Expert opinion on drug safety 20090701
-
(18)F-FDG and (18)F-FLT uptake early after cyclophosphamide and mTOR inhibition in an experimental lymphoma model.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090701
-
The 'mini-crush' technique for managing bifurcation lesions.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090701
-
Comparison of Tacrolimus and Sirolimus (Tac/Sir) versus Tacrolimus, Sirolimus, and mini-methotrexate (Tac/Sir/MTX) as acute graft-versus-host disease prophylaxis after reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090701
-
Sirolimus as primary treatment of acute graft-versus-host disease following allogeneic hematopoietic cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090701
-
Relationship between severity of renal impairment and 2-year outcomes after sirolimus-eluting stent implantation.
American heart journal 20090701
-
Relationship between neointimal coverage of sirolimus-eluting stents and lesion characteristics: a study with serial coronary angioscopy.
American heart journal 20090701
-
Transplantation: To convert or not to convert: lessons from the CONVERT trial.
Nature reviews. Nephrology 20090701
-
'Rapping' on the door of drug resistance.
Leukemia & lymphoma 20090701
-
Targeting mammalian target of rapamycin to both downregulate and disable the P-glycoprotein pump in multidrug-resistant B-cell lymphoma cell lines.
Leukemia & lymphoma 20090701
-
[Renal epithelioid angiomyolipoma].
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20090701
-
Everolimus.
Nature reviews. Drug discovery 20090701
-
Long-term outcomes comparison of different types of DES in elderly patients from a real-world experience.
The Journal of invasive cardiology 20090701
-
Defining the optimal treatment for elderly patients: lessons from real-world data.
The Journal of invasive cardiology 20090701
-
Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates.
Nature medicine 20090701
-
[Mammalian target of rapamycin, its mode of action and clinical response in metastatic clear cell carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy 20090701
-
Late stent malapposition with marked positive vascular remodeling observed only at the site of drug-eluting stents after multivessel coronary stenting.
Heart and vessels 20090701
-
Different vascular response to concurrent implantation of sirolimus- and zotarolimus-eluting stents in the same vessel.
Heart and vessels 20090701
-
Impact of sex on 3-year outcome after percutaneous coronary intervention using bare-metal and drug-eluting stents in previously untreated coronary artery disease: insights from the RESEARCH (Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital) and T-SEARCH (Taxus-Stent Evaluated at Rotterdam Cardiology Hospital) Registries.
JACC. Cardiovascular interventions 20090701
-
The efficacy of drug-eluting stents in women: a window of opportunity.
JACC. Cardiovascular interventions 20090701
-
Population pharmacokinetics of sirolimus in de novo Chinese adult renal transplant patients.
British journal of clinical pharmacology 20090701
-
[The mTOR inhibitor enhances chemosensitivity of androgen-independent prostate cancer cell line].
Zhonghua nan ke xue = National journal of andrology 20090701
-
Use of a cocktail regimen consisting of soluble galectin-1, rapamycin and histone deacetylase inhibitor may effectively prevent type 1 diabetes.
Archives of medical research 20090701
-
New mTOR inhibitor for renal cell cancer.
Oncology (Williston Park, N.Y.) 20090701
-
The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1.
Aging 20090701
-
Overproduction of cyclin D1 is dependent on activated mTORC1 signal in nasopharyngeal carcinoma: implication for therapy.
Cancer letters 20090628
-
A novel accelerated in vitro release method for biodegradable coating of drug eluting stents: Insight to the drug release mechanisms.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090628
-
Mesenchymal stem cell and immunosuppressive drug interactions.
Transplantation 20090627
-
Distribution pattern of neointimal hyperplasia following sirolimus-eluting stent implantation assessed by 3-dimensional intravascular ultrasound.
International journal of cardiology 20090626
-
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer.
Nature 20090625
-
Inhibition of the mammalian target of rapamycin signaling pathway suppresses dentate granule cell axon sprouting in a rodent model of temporal lobe epilepsy.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20090624
-
Randomized comparison of minimally invasive direct coronary artery bypass surgery versus sirolimus-eluting stenting in isolated proximal left anterior descending coronary artery stenosis.
Journal of the American College of Cardiology 20090623
-
Down-regulation of mTOR leads to up-regulation of osteoprotegerin in bone marrow cells.
Biochemical and biophysical research communications 20090619
-
m(en)TOR(ing) differentiating T helper cells.
Immunity 20090619
-
Sirolimus and everolimus induce endothelial cellular senescence via sirtuin 1 down-regulation: therapeutic implication of cilostazol after drug-eluting stent implantation.
Journal of the American College of Cardiology 20090616
-
Aging-suppressants: cellular senescence (hyperactivation) and its pharmacologic deceleration.
Cell cycle (Georgetown, Tex.) 20090615
-
Rapamycin decelerates cellular senescence.
Cell cycle (Georgetown, Tex.) 20090615
-
Forever young, slim and fit: rapamycin to the rescue.
Cell cycle (Georgetown, Tex.) 20090615
-
Pharmacologic inhibition of MEK and PI-3K converges on the mTOR/S6 pathway to decelerate cellular senescence.
Cell cycle (Georgetown, Tex.) 20090615
-
TORC1 controls degradation of the transcription factor Stp1, a key effector of the SPS amino-acid-sensing pathway in Saccharomyces cerevisiae.
Journal of cell science 20090615
-
Tacrolimus/sirolimus versus tacrolimus/mycophenolate in kidney transplantation: improved 3-year graft and patient survival in recent era.
Transplantation 20090615
-
Fluvastatin accelerates re-endothelialization impaired by local sirolimus treatment.
European journal of pharmacology 20090610
-
Biphasic activation of the mTOR pathway in the gustatory cortex is correlated with and necessary for taste learning.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20090610
-
Deregulation of mTOR signaling is involved in thymic lymphoma development in Atm-/- mice.
Biochemical and biophysical research communications 20090605
-
FDG uptake is a surrogate marker for defining the optimal biological dose of the mTOR inhibitor everolimus in vivo.
British journal of cancer 20090602
-
Comparison of inflammatory markers and angiographic outcomes after implantation of sirolimus and paclitaxel-eluting stents.
Heart (British Cardiac Society) 20090601
-
Apoptosis of CD4(+)CD25(high) T cells in response to Sirolimus requires activation of T cell receptor and is modulated by IL-2.
Cancer immunology, immunotherapy : CII 20090601
-
Polylactide-glycoli acid and rapamycin coating intraocular lens prevent posterior capsular opacification in rabbit eyes.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20090601
-
Monitoring kidney and renal cyst volumes applying MR approaches on a rapamycin treated mouse model of ADPKD.
Magma (New York, N.Y.) 20090601
-
High prevalence of ovarian cysts in premenopausal women receiving sirolimus and tacrolimus after clinical islet transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20090601
-
Rapamycin, but not cyclosporine A, inhibits vascularization and incorporation of implanted surgical meshes.
Transplant international : official journal of the European Society for Organ Transplantation 20090601
-
Combined inhibition of Dnmt and mTOR signaling inhibits formation and growth of colorectal cancer.
International journal of colorectal disease 20090601
-
Combination of immunosuppressive drugs leaves specific 'fingerprint' on gene expression in vitro.
Immunopharmacology and immunotoxicology 20090601
-
Generation of high-yield rapamycin-producing strains through protoplasts-related techniques.
Applied microbiology and biotechnology 20090601
-
Lung cavitation due to Mycobacterium xenopi in a renal transplant recipient.
Transplant infectious disease : an official journal of the Transplantation Society 20090601
-
Sirolimus-associated lymphoedema: eight new cases and a proposed mechanism.
The British journal of dermatology 20090601
-
Intracellular parasitism with Toxoplasma gondii stimulates mammalian-target-of-rapamycin-dependent host cell growth despite impaired signalling to S6K1 and 4E-BP1.
Cellular microbiology 20090601
-
A phase 2 study with a daily regimen of the oral mTOR inhibitor RAD001 (everolimus) in patients with metastatic clear cell renal cell cancer.
Cancer 20090601
-
Mammalian target of rapamycin inhibitors and their potential role in therapy in leukaemia and other haematological malignancies.
British journal of haematology 20090601
-
Rapamycin selectively reduces the association of transcripts containing complex 5' UTRs with ribosomes in C4-2B prostate cancer cells.
Journal of cellular biochemistry 20090601
-
Immunosuppressive therapy in lung transplantation: state of the art.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20090601
-
Severe multivessel coronary spasm after sirolimus-eluting stent implantation.
Journal of cardiovascular medicine (Hagerstown, Md.) 20090601
-
Intervention for jailed diagonal branch is not necessary while stenting the left anterior descending artery.
Journal of interventional cardiology 20090601
-
Delayed neointimalization on sirolimus-eluting stents: 6-month and 12-month follow up by optical coherence tomography.
Circulation journal : official journal of the Japanese Circulation Society 20090601
-
Assessment of sirolimus-eluting coronary stent implantation with aspirin plus low dose ticlopidine administration: one year results from CYPHER Stent Japan Post-Marketing Surveillance Registry (J-PMS).
Circulation journal : official journal of the Japanese Circulation Society 20090601
-
Comparison of low vs moderate dose of atorvastatin in clopidogrel resistance after coronary stenting in Korean patients with acute coronary syndrome.
Circulation journal : official journal of the Japanese Circulation Society 20090601
-
Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090601
-
[18F]fluorodeoxyglucose positron emission tomography correlates with Akt pathway activity but is not predictive of clinical outcome during mTOR inhibitor therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090601
-
Sirolimus as primary immunosuppression is associated with improved coronary vasomotor function compared with calcineurin inhibitors in stable cardiac transplant recipients.
European heart journal 20090601
-
Leucine restriction inhibits chondrocyte proliferation and differentiation through mechanisms both dependent and independent of mTOR signaling.
American journal of physiology. Endocrinology and metabolism 20090601
-
Antagonism of the mammalian target of rapamycin selectively mediates metabolic effects of epidermal growth factor receptor inhibition and protects human malignant glioma cells from hypoxia-induced cell death.
Brain : a journal of neurology 20090601
-
Expression of mTOR pathway proteins in human amniotic fluid stem cells.
International journal of molecular medicine 20090601
-
The methylation of the TSC2 promoter underlies the abnormal growth of TSC2 angiomyolipoma-derived smooth muscle cells.
The American journal of pathology 20090601
-
Black and white: rapamycin as a regulator of cardiac mTOR signaling.
Cell cycle (Georgetown, Tex.) 20090601
-
Let it be, let it be.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090601
-
Strategies for drug-eluting stent treatment of bifurcation coronary artery disease in the United States: insights from the e-Cypher S.T.L.L.R.trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090601
-
Combined inhibition of MEK and mammalian target of rapamycin abolishes phosphorylation of cyclin-dependent kinase 4 in glioblastoma cell lines and prevents their proliferation.
Cancer research 20090601
-
Improved cardiac function after sirolimus-eluting stent placement in diabetic patients by pioglitazone: combination therapy with statin.
Journal of cardiology 20090601
-
Absence of proteinuria predicts improvement in renal function after conversion to sirolimus-based immunosuppressive regimens in lung transplant survivors with chronic kidney disease.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20090601
-
Adverse effects of nicotine and immunosuppression on proximal tubular epithelial cell viability, tissue repair and oxidative stress gene expression.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20090601
-
Rapamycin down-regulates inducible nitric oxide synthase by inducing proteasomal degradation.
Biological & pharmaceutical bulletin 20090601
-
Overexpression of thymosin beta4 increases pseudopodia formation in LNCaP prostate cancer cells.
Biological & pharmaceutical bulletin 20090601
-
Long-term clinical follow-up after sirolimus-eluting stent versus bare metal stent implantation in patients with acute coronary syndrome.
Journal of interventional cardiology 20090601
-
Everolimus (RAD001): an mTOR inhibitor for the treatment of metastatic renal cell carcinoma.
Expert review of anticancer therapy 20090601
-
First-in-man use of polymer-free valsartan-eluting stents in small coronary vessels: a comparison to polymer-free rapamycin (2%)-eluting stents.
Journal of the renin-angiotensin-aldosterone system : JRAAS 20090601
-
Validation of the type 1 insulin-like growth factor receptor as a therapeutic target in renal cancer.
Molecular cancer therapeutics 20090601
-
Simultaneous blockade of the epidermal growth factor receptor/mammalian target of rapamycin pathway by epidermal growth factor receptor inhibitors and rapamycin results in reduced cell growth and survival in biliary tract cancer cells.
Molecular cancer therapeutics 20090601
-
Cyclooxygenase 2 mediates the antiangiogenic effect of rapamycin in Ewing sarcoma.
Journal of pediatric surgery 20090601
-
Infarct size is increased in female post-MI rats treated with rapamycin.
Canadian journal of physiology and pharmacology 20090601
-
Impact of stent length on restenosis in patients with acute myocardial infarction treated with primary percutaneous coronary intervention: analysis based on data from the Trial to Assess the Use of the Cypher Stent in Acute Myocardial Infarction Treated with Balloon Angioplasty (TYPHOON).
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090601
-
Reproducibility of quantitative optical coherence tomography for stent analysis.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090601
-
Treatment of refractory chronic urticaria with sirolimus.
Archives of dermatology 20090601
-
Conversion from calcineurin inhibitors to sirolimus reduces vascularization and thickness of post-transplant cutaneous squamous cell carcinomas.
Anticancer research 20090601
-
Inhibition of IGF-I receptor signaling in combination with rapamycin or temsirolimus increases MYC-N phosphorylation.
Anticancer research 20090601
-
The role of antiangiogenesis therapy: bevacizumab and beyond.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20090601
-
Efficacy of combined inhibition of mTOR and ERK/MAPK pathways in treating a tuberous sclerosis complex cell model.
Journal of genetics and genomics = Yi chuan xue bao 20090601
-
Impact of target lesion and nontarget lesion cardiac events on 5-year clinical outcomes after sirolimus-eluting or bare-metal stenting.
JACC. Cardiovascular interventions 20090601
-
The PASEO (PaclitAxel or Sirolimus-Eluting Stent Versus Bare Metal Stent in Primary Angioplasty) Randomized Trial.
JACC. Cardiovascular interventions 20090601
-
The risk of stent thrombosis in patients with acute coronary syndromes treated with bare-metal and drug-eluting stents.
JACC. Cardiovascular interventions 20090601
-
Clinical impact of polymorphisms of transport proteins and enzymes involved in the metabolism of immunosuppressive drugs.
Transplantation proceedings 20090601
-
Long-term follow-up of 100 high-risk renal transplant recipients converted from calcineurin inhibitors to sirolimus: a single center experience.
Transplantation proceedings 20090601
-
The effect of Malononitrilamides (FK778) on phenotypic properties of human peripheral dendritic cells.
Transplantation proceedings 20090601
-
Effect of cyclosporine and sirolimus on fatty acid desaturase activities in cultured HEPG2 cells.
Transplantation proceedings 20090601
-
[Effects of sirolimus on the growth of transplanted hepatocellular carcinoma].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090601
-
Two-year outcomes of the sirolimus-eluting stent according to unprotected left main lesion.
Clinical cardiology 20090601
-
[The MULTISTRATEGY study].
Giornale italiano di cardiologia (2006) 20090601
-
Decreased acute rejection and improved renal allograft survival using sirolimus and low-dose calcineurin inhibitors without induction therapy.
The International journal of artificial organs 20090601
-
[Combined rapamycin eye drop in nanometer vector and poly (lactic acid) wafers of cyclosporine A effectively prevents high-risk corneal allograft rejection in rabbits].
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20090601
-
Randomized comparison of the Nobori Biolimus A9-eluting coronary stent with the Taxus Liberté paclitaxel-eluting coronary stent in patients with stenosis in native coronary arteries: the NOBORI 1 trial--Phase 2.
Circulation. Cardiovascular interventions 20090601
-
Bioabsorbable coronary stents.
Circulation. Cardiovascular interventions 20090601
-
'Intracoronary whirling current phenomenon' and thrombus formation after sirolimus-eluting stent implantation visualized by optical coherence tomography.
Circulation. Cardiovascular interventions 20090601
-
Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy.
Aging 20090601
-
Three-year clinical outcome of percutaneous treatment of bifurcation lesions in multivessel coronary artery disease with the sirolimus-eluting stent: insights from the Arterial Revascularisation Therapies Study, part II (ARTS II).
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090601
-
Long-term outcome after the V stenting technique in de novo bifurcation lesions using drug-eluting stents.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090601
-
Percutaneous coronary intervention with oral sirolimus and bare metal stents has comparable safety and efficacy to treatment with drug eluting stents, but with significant cost saving: long-term follow-up results from the randomised, controlled ORAR III (Oral Rapamycin in ARgentina) study.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090601
-
Impact of plasma and whole-blood anticoagulant counter ion choice on drug stability and matrix effects during bioanalysis.
Bioanalysis 20090601
-
Impressive sirolimus-eluting stent fracture immediately after stent implantation: a case report.
International journal of cardiology 20090529
-
Changes in sodium pump expression dictate the effects of ouabain on cell growth.
The Journal of biological chemistry 20090529
-
Mammalian target of rapamycin complex 1 (mTORC1) activity is associated with phosphorylation of raptor by mTOR.
The Journal of biological chemistry 20090529
-
Akt signals through the mammalian target of rapamycin pathway to regulate CNS myelination.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20090527
-
The mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsy.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20090527
-
[Monitoring and adjustment of immunosuppression after heart transplantation].
Revue medicale suisse 20090527
-
Fluorescent probes to characterise FK506-binding proteins.
Chembiochem : a European journal of chemical biology 20090525
-
Multimodal dynamic imaging of therapeutic biomedical coatings in aqueous medium.
Langmuir : the ACS journal of surfaces and colloids 20090519
-
Chemopreventive efficacy of rapamycin on Peutz-Jeghers syndrome in a mouse model.
Cancer letters 20090518
-
Acute myocardial infarction as a consequence of stent fracture and plaque rupture after sirolimus-eluting stent implantation.
International journal of cardiology 20090515
-
Various optical coherence tomographic findings in restenotic lesions after sirolimus-eluting stent implantation.
International journal of cardiology 20090515
-
Use of multiple overlapping sirolimus-eluting stents for treatment of long coronary artery lesions: results from a single-center registry in 318 consecutive patients.
International journal of cardiology 20090515
-
Targeting mTOR in renal cell carcinoma.
Cancer 20090515
-
Acute liver transplant rejection upon immunosuppression withdrawal in a tolerance induction trial: potential role of IFN-gamma-secreting CD8+ T cells.
Transplantation 20090515
-
Long-term treatment of sirolimus but not cyclosporine ameliorates diabetic nephropathy in the rat.
Transplantation 20090515
-
The challenge of achieving target drug concentrations in clinical trials: experience from the Symphony study.
Transplantation 20090515
-
Disposition of everolimus in mdr1a-/1b- mice and after a pre-treatment of lapatinib in Swiss mice.
Biochemical pharmacology 20090515
-
Predictors of heightened platelet reactivity despite dual-antiplatelet therapy in patients undergoing percutaneous coronary intervention.
The American journal of cardiology 20090515
-
Rapamycin prevents early onset of tumorigenesis in an oral-specific K-ras and p53 two-hit carcinogenesis model.
Cancer research 20090515
-
Paclitaxel- versus sirolimus-eluting stents for unprotected left main coronary artery disease.
Journal of the American College of Cardiology 20090512
-
Left main coronary artery stenting: crossing the Rubicon.
Journal of the American College of Cardiology 20090512
-
Regulation of RNA polymerase III transcription involves SCH9-dependent and SCH9-independent branches of the target of rapamycin (TOR) pathway.
The Journal of biological chemistry 20090508
-
XAP2 inhibits glucocorticoid receptor activity in mammalian cells.
FEBS letters 20090506
-
A prospective, randomized, 6-month comparison of the coronary vasomotor response associated with a zotarolimus- versus a sirolimus-eluting stent: differential recovery of coronary endothelial dysfunction.
Journal of the American College of Cardiology 20090505
-
Differences in restenosis rate with different drug-eluting stents in patients with and without diabetes mellitus: a report from the SCAAR (Swedish Angiography and Angioplasty Registry).
Journal of the American College of Cardiology 20090505
-
Successful treatment of a child having generalized Kaposi's sarcoma after living donor liver transplantation with conversion to sirolimus.
Pediatric transplantation 20090501
-
Experiences and practical conclusions concerning temsirolimus use and adverse event management in advanced renal cell carcinoma within a compassionate use program in Germany.
Cancer chemotherapy and pharmacology 20090501
-
Sirolimus inhibits the growth and metastatic progression of hepatocellular carcinoma.
Journal of cancer research and clinical oncology 20090501
-
PTEN deficiency is a common defect in juvenile myelomonocytic leukemia.
Leukemia research 20090501
-
Calcineurin inhibitor-free GVHD prophylaxis with sirolimus, mycophenolate mofetil and ATG in Allo-SCT for leukemia patients with high relapse risk: an observational cohort study.
Bone marrow transplantation 20090501
-
Decrease in sirolimus-induced proteinuria after switch to everolimus in a liver transplant recipient with diabetic nephropathy.
Transplant international : official journal of the European Society for Organ Transplantation 20090501
-
Impact of clopidogrel resistance on thrombotic events after percutaneous coronary intervention with drug-eluting stent.
Thrombosis research 20090501
-
Induction of iodide uptake in transformed thyrocytes: a compound screening in cell lines.
European journal of nuclear medicine and molecular imaging 20090501
-
Suppression of mTOR complex 2-dependent AKT phosphorylation in melanoma cells by combined treatment with rapamycin and LY294002.
The British journal of dermatology 20090501
-
Ready for a comeback of natural products in oncology.
Biochemical pharmacology 20090501
-
Differential effects of immunosuppressive drugs on COX-2 activity in vitro and in kidney transplant patients in vivo.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090501
-
Assaying autophagic activity in transgenic GFP-Lc3 and GFP-Gabarap zebrafish embryos.
Autophagy 20090501
-
Novel agents for renal cell carcinoma require novel selection paradigms to optimise first-line therapy.
Cancer treatment reviews 20090501
-
The eIF4E-binding proteins are modifiers of cytoplasmic eIF4E relocalization during the heat shock response.
American journal of physiology. Cell physiology 20090501
-
LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.
Acta physiologica (Oxford, England) 20090501
-
Tolerability of first-line therapy for metastatic renal cell carcinoma.
Cancer treatment reviews 20090501
-
Recent advances in molecular targeted therapy for metastatic renal cell carcinoma.
International journal of urology : official journal of the Japanese Urological Association 20090501
-
[Targeted therapies and their indications in solid neoplasias].
La Revue de medecine interne 20090501
-
Quantitation of selective autophagic protein aggregate degradation in vitro and in vivo using luciferase reporters.
Autophagy 20090501
-
Comparative healing response after sirolimus- and paclitaxel-eluting stent implantation in a pig model of restenosis.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090501
-
Targeting of mTOR is associated with decreased growth and decreased VEGF expression in acute myeloid leukaemia cells.
European journal of clinical investigation 20090501
-
Long-term small molecule and protein elution from TiO2 nanotubes.
Nano letters 20090501
-
Rapamycin reduces high-amplitude, mechanical stretch-induced apoptosis in pulmonary microvascular endothelial cells.
Microvascular research 20090501
-
Targeting the mTOR signaling network for cancer therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090501
-
Progress in the treatment of neuroendocrine tumors.
Current oncology reports 20090501
-
Targeted therapies in metastatic renal cancer in 2009.
BJU international 20090501
-
Early and limited use of tacrolimus to avoid rejection in an alemtuzumab and sirolimus regimen for kidney transplantation: clinical results and immune monitoring.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090501
-
Ultra-performance hydrophilic interaction liquid chromatography/tandem mass spectrometry for the determination of everolimus in mouse plasma.
Rapid communications in mass spectrometry : RCM 20090501
-
Re-restenosis and target lesion revascularization after treatment of sirolimus-eluting stent restenosis: retrospective analysis of 4 Japanese hospitals.
Circulation journal : official journal of the Japanese Circulation Society 20090501
-
Adenovirus-mediated eukaryotic initiation factor 4E binding protein-1 in combination with rapamycin inhibits tumor growth of pancreatic ductal adenocarcinoma in vivo.
International journal of oncology 20090501
-
Atg17 recruits Atg9 to organize the pre-autophagosomal structure.
Genes to cells : devoted to molecular & cellular mechanisms 20090501
-
Efficacy of Xience/promus versus Cypher in rEducing Late Loss after stENTing (EXCELLENT) trial: study design and rationale of a Korean multicenter prospective randomized trial.
American heart journal 20090501
-
Relationship of deregulated signaling converging onto mTOR with prognosis and classification of lung adenocarcinoma shown by two independent in silico analyses.
Cancer research 20090501
-
Transplantation: sirolimus plus calcineurin inhibitors in transplantation.
Nature reviews. Nephrology 20090501
-
New oral treatment for kidney cancer approved.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090501
-
Combination of C-reactive protein and cardiac troponin I for predicting adverse cardiac events after sirolimus-eluting stent implantation.
Coronary artery disease 20090501
-
Recent advances in the chemistry, biosynthesis and pharmacology of rapamycin analogs.
Natural product reports 20090501
-
Significant response after treatment with the mTOR inhibitor sirolimus in combination with carboplatin and paclitaxel in metastatic melanoma patients.
Journal of the American Academy of Dermatology 20090501
-
PTEN deficiency is fully penetrant for prostate adenocarcinoma in C57BL/6 mice via mTOR-dependent growth.
The American journal of pathology 20090501
-
Comparison of medium-term outcomes obtained with drug-eluting stents and coronary artery bypass grafts in an unselected population of diabetic patients with multivessel coronary disease. Propensity score analysis.
Revista espanola de cardiologia 20090501
-
Beyond monoclonal antibodies: new therapeutic agents in non-Hodgkin's lymphomas.
The oncologist 20090501
-
Intravascular ultrasound guidance of multiple drug-eluting stent implantation in lesions associated with coronary aneurysms.
The Journal of invasive cardiology 20090501
-
Percutaneous revascularization of chronic total occlusion of left anterior descending artery using contralateral injection via isolated conus artery.
The Journal of invasive cardiology 20090501
-
Dual targeting of AKT and mammalian target of rapamycin: a potential therapeutic approach for malignant peripheral nerve sheath tumor.
Molecular cancer therapeutics 20090501
-
Xience V everolimus-eluting coronary stent.
Expert review of medical devices 20090501
-
Efficacy on renal function of early conversion from cyclosporine to sirolimus 3 months after renal transplantation: concept study.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090501
-
The applicability of mTOR inhibition in solid tumors.
Current cancer drug targets 20090501
-
Atherosclerotic and thrombogenic neointima formed over sirolimus drug-eluting stent: an angioscopic study.
JACC. Cardiovascular imaging 20090501
-
One step forward and two steps back with drug-eluting-stents: from preventing restenosis to causing late thrombosis and nouveau atherosclerosis.
JACC. Cardiovascular imaging 20090501
-
Prospective clinical trial comparing two immunosuppressive regimens, tacrolimus and mycophenolate mofetil versus everolimus and low-dose cyclosporine, in de novo renal transplant recipients: results at 6 months follow-up.
Transplantation proceedings 20090501
-
Cardiovascular risk profile in kidney transplant recipients treated with two immunosuppressive regimens: tacrolimus and mycophenolate mofetil versus everolimus and low-dose cyclosporine.
Transplantation proceedings 20090501
-
Immunosuppressive agents and metabolic factors of cardiovascular risk in renal transplant recipients.
Transplantation proceedings 20090501
-
Posttransplant proteinuria associated with everolimus.
Transplantation proceedings 20090501
-
Immunosuppressive switch to sirolimus in renal dysfunction after liver transplantation.
Transplantation proceedings 20090501
-
The impact of everolimus on renal function in maintenance liver transplantation.
Transplantation proceedings 20090501
-
Does everolimus associated with a low dose of cyclosporine in long-term cardiac transplant recipients improve renal function? Initial experience.
Transplantation proceedings 20090501
-
Rapamycin reduces proteinuria and renal damage in the rat remnant kidney model.
Transplantation proceedings 20090501
-
1-year results of the hydroxyapatite polymer-free sirolimus-eluting stent for the treatment of single de novo coronary lesions: the VESTASYNC I trial.
JACC. Cardiovascular interventions 20090501
-
A randomized optical coherence tomography study of coronary stent strut coverage and luminal protrusion with rapamycin-eluting stents.
JACC. Cardiovascular interventions 20090501
-
Incomplete stent apposition and delayed tissue coverage are more frequent in drug-eluting stents implanted during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction than in drug-eluting stents implanted for stable/unstable angina: insights from optical coherence tomography.
JACC. Cardiovascular interventions 20090501
-
Local determinants of thrombus formation following sirolimus-eluting stent implantation assessed by optical coherence tomography.
JACC. Cardiovascular interventions 20090501
-
From a foggy sight to a clear vision.
JACC. Cardiovascular interventions 20090501
-
Biodegradable polymer films for releasing nanovehicles containing sirolimus.
Drug delivery 20090501
-
[Drug-eluting stents - new standard of restenosis treatment].
Kardiologia polska 20090501
-
Combined therapy of CD4(+)CD25(+) regulatory T cells with low-dose sirolimus, but not calcineurin inhibitors, preserves suppressive function of regulatory T cells and prolongs allograft survival in mice.
International immunopharmacology 20090501
-
In vitro induced CD4(+)CD25(+)Foxp3(+) Tregs attenuate hepatic ischemia-reperfusion injury.
International immunopharmacology 20090501
-
[Intravascular ultrasound assessment of sirolimus-eluting stent restenosis or thrombosis after stent implantation].
Zhonghua xin xue guan bing za zhi 20090501
-
Five-year follow-up after sirolimus-eluting stent implantation results of the SIRIUS (Sirolimus-Eluting Stent in De-Novo Native Coronary Lesions) Trial.
Journal of the American College of Cardiology 20090428
-
Sirolimus in kidney transplantation indications and practical guidelines: de novo sirolimus-based therapy without calcineurin inhibitors.
Transplantation 20090427
-
Sirolimus-based therapy for kidney transplantation from expanded criteria donors.
Transplantation 20090427
-
Minimizing the risk of posttransplant malignancy.
Transplantation 20090427
-
Management of side effects of sirolimus therapy.
Transplantation 20090427
-
Inhibitors of the mammalian target of rapamycin and transplant tolerance.
Transplantation 20090427
-
Review of symposium. Sirolimus in kidney transplantation.
Transplantation 20090427
-
Protocol conversion from a calcineurin inhibitor based therapy to sirolimus.
Transplantation 20090427
-
Rapamycin-eluting stents in the arterial duct: experimental observations in the pig model.
Circulation 20090421
-
Focus Issue: demystifying mTOR signaling.
Science signaling 20090421
-
The pharmacology of mTOR inhibition.
Science signaling 20090421
-
Immune regulation by rapamycin: moving beyond T cells.
Science signaling 20090421
-
Frequency, predictors and outcome of stent fracture after sirolimus-eluting stent implantation.
International journal of cardiology 20090417
-
Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway.
Clinical cancer research : an official journal of the American Association for Cancer Research 20090415
-
Efficacy of systemically administered oncolytic vaccinia virotherapy for malignant gliomas is enhanced by combination therapy with rapamycin or cyclophosphamide.
Clinical cancer research : an official journal of the American Association for Cancer Research 20090415
-
Serial intravascular ultrasound analysis of peri-stent remodeling and proximal and distal edge effects after sirolimus-eluting or paclitaxel-eluting stent implantation in patients with diabetes mellitus.
The American journal of cardiology 20090415
-
Activating transcription factor 4 and CCAAT/enhancer-binding protein-beta negatively regulate the mammalian target of rapamycin via Redd1 expression in response to oxidative and endoplasmic reticulum stress.
Free radical biology & medicine 20090415
-
Sirolimus to replace calcineurin inhibitors? Too early yet.
Lancet (London, England) 20090411
-
Potentiating effects of RAD001 (Everolimus) on vincristine therapy in childhood acute lymphoblastic leukemia.
Blood 20090402
-
The role of mTOR in the management of solid tumors: an overview.
Cancer treatment reviews 20090401
-
Comparison of changes in early inflammatory markers between sirolimus- and paclitaxel-eluting stent implantation.
Cardiovascular drugs and therapy 20090401
-
Safe conversion of mycophenolate mofetil to azathioprine in kidney transplant recipients with sirolimus-based immunosuppression.
Nephrology (Carlton, Vic.) 20090401
-
The evaluation of primary stenting of sirolimus-eluting versus bare-metal stents in the treatment of atherosclerotic lesions of crural arteries.
European radiology 20090401
-
S6K1 is involved in polyploidization through its phosphorylation at Thr421/Ser424.
Journal of cellular physiology 20090401
-
Early systemic inflammatory response to drug-eluting stents implantation: the heart of the difference? Editorial to: 'Comparison of changes in early inflammatory markers between sirolimus- and paclitaxel-eluting stent implantation' by Li et al.
Cardiovascular drugs and therapy 20090401
-
Role of the Botrytis cinerea FKBP12 ortholog in pathogenic development and in sulfur regulation.
Fungal genetics and biology : FG & B 20090401
-
Rapamycin prevents and breaks the anti-CD3-induced tolerance in NOD mice.
Diabetes 20090401
-
Rapamycin reduces seizure frequency in tuberous sclerosis complex.
Journal of child neurology 20090401
-
Everolimus and sirolimus antagonize tacrolimus based calcineurin inhibition via competition for FK-binding protein 12.
Biochemical pharmacology 20090401
-
Autophagy in coxsackievirus-infected neurons.
Autophagy 20090401
-
Relevance of cytotoxic alloreactivity under different immunosuppressive regimens in clinical islet cell transplantation.
Clinical and experimental immunology 20090401
-
Uremic cardiac hypertrophy is reversed by rapamycin but not by lowering of blood pressure.
Kidney international 20090401
-
The prolyl isomerase Pin1 interacts with a ribosomal protein S6 kinase to enhance insulin-induced AP-1 activity and cellular transformation.
Carcinogenesis 20090401
-
Correlation between quantitative angiographic and intravascular ultrasound parameters in patients treated with sirolimus analogous-eluting stents.
The international journal of cardiovascular imaging 20090401
-
Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis.
The Journal of physiology 20090401
-
Both tacrolimus and sirolimus decrease Th1/Th2 ratio, and increase regulatory T lymphocytes in the liver after ischemia/reperfusion.
Laboratory investigation; a journal of technical methods and pathology 20090401
-
Amino acid-sensing mTOR signaling is involved in modulation of lipolysis by chronic insulin treatment in adipocytes.
American journal of physiology. Endocrinology and metabolism 20090401
-
PI3K and mTOR inhibitors: a new generation of targeted anticancer agents.
Current opinion in cell biology 20090401
-
Treatment with sirolimus results in complete responses in patients with autoimmune lymphoproliferative syndrome.
British journal of haematology 20090401
-
Differential control of allo-antigen-specific regulatory T cells and effector T cells by anti-CD4 and other agents in establishing transplantation tolerance.
International immunology 20090401
-
Tubers and tumors: rapamycin therapy for benign and malignant tumors.
Current opinion in cell biology 20090401
-
A polymer-free dual drug-eluting stent in patients with coronary artery disease: a randomized trial vs. polymer-based drug-eluting stents.
European heart journal 20090401
-
Myeloma cell growth inhibition is augmented by synchronous inhibition of the insulin-like growth factor-1 receptor by NVP-AEW541 and inhibition of mammalian target of rapamycin by Rad001.
Anti-cancer drugs 20090401
-
Comparison of the systemic levels of inflammatory markers after percutaneous coronary intervention with bare metal versus sirolimus-eluting stents.
Journal of interventional cardiology 20090401
-
Repetitive stretch suppresses denervation-induced atrophy of soleus muscle in rats.
Muscle & nerve 20090401
-
Targeting mTOR with rapamycin: one dose does not fit all.
Cell cycle (Georgetown, Tex.) 20090401
-
Combining sirolimus-eluting stents and external irradiation in cholesterol-fed rabbits increased incomplete stent apposition and decreased re-endothelialization.
Journal of cardiovascular pharmacology 20090401
-
Novel neointimal formation over sirolimus-eluting stents identified by coronary angioscopy and optical coherence tomography.
Journal of cardiology 20090401
-
A qualitative and quantitative angiographic analysis of stent fracture late following sirolimus-eluting stent implantation.
The American journal of cardiology 20090401
-
One-year outcomes from the TAXUS express stent versus cypher stent.
The American journal of cardiology 20090401
-
Sirolimus and mTORC1: centre stage in the story of what makes muscles bigger?
The Journal of physiology 20090401
-
Management of chronic allograft nephropathy: a systematic review.
Clinical journal of the American Society of Nephrology : CJASN 20090401
-
No major neurologic complications with sirolimus use in heart transplant recipients.
Mayo Clinic proceedings 20090401
-
The HER-2 receptor and breast cancer: ten years of targeted anti-HER-2 therapy and personalized medicine.
The oncologist 20090401
-
Neuroendocrine tumors: nursing implications for oral targeted agents and patient management: Part II.
Clinical journal of oncology nursing 20090401
-
Critical role for hypothalamic mTOR activity in energy balance.
Cell metabolism 20090401
-
The toxicities of modern targeted therapies: learning from the price of progress.
Targeted oncology 20090401
-
Zotarolimus for the treatment of coronary artery disease: pathophysiology, DES design, clinical evaluation and future perspective.
Expert opinion on pharmacotherapy 20090401
-
Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition.
Molecular cancer therapeutics 20090401
-
Targeting melanoma with dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitors.
Molecular cancer research : MCR 20090401
-
Rapamycin protects against high fat diet-induced obesity in C57BL/6J mice.
Journal of pharmacological sciences 20090401
-
Prospects for mTOR targeting in adult T cell leukemia.
Leukemia & lymphoma 20090401
-
Rapamycin and curcumin induce apoptosis in primary resting B chronic lymphocytic leukemia cells.
Leukemia & lymphoma 20090401
-
mTOR inhibition and adult T-cell leukemia.
Leukemia & lymphoma 20090401
-
Targeting the mTOR pathway using deforolimus in cancer therapy.
Future oncology (London, England) 20090401
-
Hypertension induced by immunosuppressive drugs: a comparative analysis between sirolimus and cyclosporine.
Transplantation proceedings 20090401
-
Sirolimus in pediatric liver transplantation: a single-center experience.
Transplantation proceedings 20090401
-
Sirolimus-induced drug fever in a renal transplant patient: a case report.
Transplantation proceedings 20090401
-
Mucosa-associated lymphoid tissue gastric lymphoma regression in a renal transplant patient after conversion of the immunosuppression to sirolimus: a case report.
Transplantation proceedings 20090401
-
Safety of an immunosuppressant protocol based on sirolimus in liver transplant recipients with malignancies or high risk of tumor recurrence.
Transplantation proceedings 20090401
-
Right adrenal metastases of hepatocarcinoma after liver transplantation: case report and literature review.
Transplantation proceedings 20090401
-
mTOR in renal cell cancer: modulator of tumor biology and therapeutic target.
Expert review of molecular diagnostics 20090401
-
Novel side branch ostial stent.
Journal of interventional cardiology 20090401
-
[Effect of rapamycin on proliferation, apoptosis and regulation of chemokine receptor CXCR4 in RPMI8226 cells].
Zhongguo shi yan xue ye xue za zhi 20090401
-
The emerging safety profile of mTOR inhibitors, a novel class of anticancer agents.
Targeted oncology 20090401
-
Drug-eluting stents versus bare-metal stents in diabetic patients with ST-segment elevation acute myocardial infarction: a pooled analysis of individual patient data from seven randomized trials.
Revista espanola de cardiologia 20090401
-
RAD001 (Everolimus) Can prevent tamoxifen-related endometrial and stromal hyperplasia.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20090401
-
Rapamycin effects on mTOR signaling in benign, premalignant and malignant human breast epithelial cells.
Anticancer research 20090401
-
Treatment for the recurrence of hepatocellular carcinoma following liver transplantation: what is the best strategy?
Cancer biology & therapy 20090401
-
Cost-effectiveness of the real-world use of drug-eluting stents at 9-month follow-up: results from the Sicilian DES Registry.
Journal of cardiovascular medicine (Hagerstown, Md.) 20090401
-
Lowering the dose of sirolimus, released from a nonpolymeric hydroxyapatite coated coronary stent, reduces signs of delayed healing.
JACC. Cardiovascular interventions 20090401
-
Durability of antirestenotic efficacy in drug-eluting stents with and without permanent polymer.
JACC. Cardiovascular interventions 20090401
-
Temporal course of neointimal formation after drug-eluting stent placement: is our understanding of restenosis changing?
JACC. Cardiovascular interventions 20090401
-
Safety and efficacy of biodegradable polymer-coated sirolimus-eluting stents in 'real-world' practice: 18-month clinical and 9-month angiographic outcomes.
JACC. Cardiovascular interventions 20090401
-
The excel stent: a good DES, but can we really stop clopidogrel after 6 months?
JACC. Cardiovascular interventions 20090401
-
Rare diseases offer insights into autism spectrum disorders. Preliminary laboratory studies suggest new biological targets for intervention.
The Harvard mental health letter 20090401
-
Drug-eluting coronary stents: many meta-analyses, little benefit.
Prescrire international 20090401
-
Frequency and clinical consequences associated with sidebranch occlusion during stent implantation using zotarolimus-eluting and paclitaxel-eluting coronary stents.
Circulation. Cardiovascular interventions 20090401
-
Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling.
Molecular cell 20090327
-
9-month clinical, angiographic, and intravascular ultrasound results of a prospective evaluation of the Axxess self-expanding biolimus A9-eluting stent in coronary bifurcation lesions: the DIVERGE (Drug-Eluting Stent Intervention for Treating Side Branches Effectively) study.
Journal of the American College of Cardiology 20090324
-
Molecular events in the activation of B cells and macrophages by a non-microbial TLR4 agonist, G1-4A from Tinospora cordifolia.
Immunology letters 20090324
-
mTORC1 activation regulates beta-cell mass and proliferation by modulation of cyclin D2 synthesis and stability.
The Journal of biological chemistry 20090320
-
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1.
The Journal of biological chemistry 20090320
-
Evaluation of neointimal coverage of overlapping sirolimus-eluting stents by optical coherence tomography.
Chinese medical journal 20090320
-
Long-term clinical outcomes after bioabsorbable polymer- and durable polymer-based sirolimus-eluting stents implantation: two-year follow-up results from a large single-center database.
Chinese medical journal 20090320
-
Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR.
Science signaling 20090317
-
Aberrant hyperactivation of akt and Mammalian target of rapamycin complex 1 signaling in sporadic chordomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 20090315
-
CDC25B mediates rapamycin-induced oncogenic responses in cancer cells.
Cancer research 20090315
-
A novel JAK3 inhibitor, R348, attenuates chronic airway allograft rejection.
Transplantation 20090315
-
Mycophenolate and sirolimus as calcineurin inhibitor-free immunosuppression improves renal function better than calcineurin inhibitor-reduction in late cardiac transplant recipients with chronic renal failure.
Transplantation 20090315
-
A bioabsorbable everolimus-eluting coronary stent system (ABSORB): 2-year outcomes and results from multiple imaging methods.
Lancet (London, England) 20090314
-
Clinical outcome of patients with chronic total occlusion treated with drug-eluting stents.
International journal of cardiology 20090306
-
S6 kinase 1 regulates estrogen receptor alpha in control of breast cancer cell proliferation.
The Journal of biological chemistry 20090306
-
Rapamycin induces transactivation of the EGFR and increases cell survival.
Oncogene 20090305
-
Targeting mTOR: something old, something new.
Journal of the National Cancer Institute 20090304
-
A randomized comparison of sirolimus- versus paclitaxel-eluting stent implantation in patients with diabetes mellitus 2-year clinical outcomes of the DES-DIABETES trial.
Journal of the American College of Cardiology 20090303
-
Nanoscale mechanical measurement determination of the glass transition temperature of poly(lactic acid)/everolimus coated stents in air and dissolution media.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090302
-
Phosphorylation of p70S6 kinase predicts overall survival in patients with clear margin-resected hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver 20090301
-
The effect of switching from calcineurin inhibitor to sirolimus on the incidence of skin cancers in kidney transplant recipients.
Journal of the European Academy of Dermatology and Venereology : JEADV 20090301
-
Activation of interleukin-6/STAT3 in rat cholangiocyte proliferation induced by lipopolysaccharide.
Digestive diseases and sciences 20090301
-
A pilot trial of the mTOR (mammalian target of rapamycin) inhibitor RAD001 in patients with advanced B-CLL.
Annals of hematology 20090301
-
Sirolimus as a potential radiosensitizer in squamous cell cancer of the head and neck.
Head & neck 20090301
-
Negative vascular remodelling after implantation of bioabsorbable magnesium alloy stents in porcine coronary arteries: a randomised comparison with bare-metal and sirolimus-eluting stents.
Heart (British Cardiac Society) 20090301
-
Hypersensitivity of Ph-positive lymphoid cell lines to rapamycin: Possible clinical application of mTOR inhibitor.
Leukemia research 20090301
-
Liquid chromatographic method for the determination of sirolimus in blood using electrochemical detection.
Biomedical chromatography : BMC 20090301
-
A pilot study of everolimus and gefitinib in the treatment of recurrent glioblastoma (GBM).
Journal of neuro-oncology 20090301
-
Factors associated with proteinuria in renal transplant recipients treated with sirolimus.
Transplant international : official journal of the European Society for Organ Transplantation 20090301
-
Conversion to everolimus monotherapy in maintenance liver transplantation: feasibility, safety, and impact on renal function.
Transplant international : official journal of the European Society for Organ Transplantation 20090301
-
Sirolimus monotherapy effectiveness in liver transplant recipients with renal dysfunction due to calcineurin inhibitors.
Journal of clinical gastroenterology 20090301
-
Rapamycin inhibits in vitro growth and release of angiogenetic factors in human bladder cancer.
Urology 20090301
-
Nitrogen catabolite repression-sensitive transcription as a readout of Tor pathway regulation: the genetic background, reporter gene and GATA factor assayed determine the outcomes.
Genetics 20090301
-
Immunoregulatory profiles in liver transplant recipients on different immunosuppressive agents.
Human immunology 20090301
-
Stimulation of skeletal muscle myofibrillar protein synthesis, p70 S6 kinase phosphorylation, and ribosomal protein S6 phosphorylation by inhibition of myostatin in mature mice.
American journal of physiology. Endocrinology and metabolism 20090301
-
Angiographic patterns of restenosis after sirolimus-eluting stent implantation.
Circulation journal : official journal of the Japanese Circulation Society 20090301
-
Everolimus attenuates neointimal hyperplasia in cultured human saphenous vein grafts.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20090301
-
Treatment of severe aplastic anemia with a combination of horse antithymocyte globulin and cyclosporine, with or without sirolimus: a prospective randomized study.
Haematologica 20090301
-
Combined inhibition of MEK and mTOR signaling inhibits initiation and progression of colorectal cancer.
Cancer investigation 20090301
-
Effects of oral posaconazole on the pharmacokinetics of sirolimus.
Current medical research and opinion 20090301
-
Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor.
British journal of pharmacology 20090301
-
Trypanosome TOR complex 2 functions in cytokinesis.
Cell cycle (Georgetown, Tex.) 20090301
-
mTOR inhibitor RAD001 (everolimus) has antiangiogenic/vascular properties distinct from a VEGFR tyrosine kinase inhibitor.
Clinical cancer research : an official journal of the American Association for Cancer Research 20090301
-
Phospho-p70S6K/p85S6K and cdc2/cdk1 are novel targets for diffuse large B-cell lymphoma combination therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 20090301
-
Percutaneous coronary intervention for a right coronary artery stent occlusion using retrograde delivery of a sirolimus-eluting stent via a septal perforator.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090301
-
Value of drug-eluting stents in cardiac transplant recipients.
The American journal of cardiology 20090301
-
Oral rapamycin attenuates inflammation and enhances stability of atherosclerotic plaques in rabbits independent of serum lipid levels.
British journal of pharmacology 20090301
-
Determination of blood sirolimus concentrations in liver and kidney transplant recipients using the Innofluor fluorescence polarization immunoassay: comparison with the microparticle enzyme immunoassay and high-performance liquid chromatography-ultraviolet method.
Upsala journal of medical sciences 20090301
-
Immunosuppressive treatment for aplastic anemia: are we hitting the ceiling?
Haematologica 20090301
-
Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells.
Nature medicine 20090301
-
Recommendations from the Spanish Oncology Genitourinary Group for the treatment of metastatic renal cancer.
Cancer chemotherapy and pharmacology 20090301
-
ID2-VEGF-related pathways in the pathogenesis of Kaposi's sarcoma: a link disrupted by rapamycin.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090301
-
Using the stochastic collocation method for the uncertainty quantification of drug concentration due to depot shape variability.
IEEE transactions on bio-medical engineering 20090301
-
Recent advances in the systemic treatment of metastatic papillary renal cancer.
Expert review of anticancer therapy 20090301
-
Inhibition of Janus kinase 2 and signal transduction and activator of transcription 3 protect against cecal ligation and puncture-induced multiple organ damage and mortality.
The Journal of trauma 20090301
-
Drug exposure and perceived adverse drug events reported by liver-transplant patients.
International journal of clinical pharmacology and therapeutics 20090301
-
Safety and efficacy of 2.5-mm sirolimus-eluting stent implantation at lower deployment pressures in very small vessels (<2.5 mm).
Coronary artery disease 20090301
-
Prolonged dual antiplatelet therapy improves clinical outcomes in high-risk patients implanted with sirolimus-eluting stents.
Clinical cardiology 20090301
-
Late conversion from calcineurin inhibitor-based to sirolimus-based immunosuppression due to chronic toxicity: a prospective study with protocol biopsy amendment.
Transplantation proceedings 20090301
-
[Prevention of hepatic tumor growth and metastasis in rats with rapamycin].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090301
-
Incidence of stent thrombosis in patients with drug eluting stents and short-term dual antiplatelet therapy.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090301
-
Re-examining minimal luminal diameter relocation and quantitative coronary angiography--intravascular ultrasound correlations in stented saphenous vein grafts: methodological insights from the randomised RRISC trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090301
-
Advances in the pathogenesis and treatment of polycystic kidney disease.
Current opinion in nephrology and hypertension 20090301
-
Mini-crush versus T-provisional techniques in bifurcation lesions: clinical and angiographic long-term outcome after implantation of drug-eluting stents.
JACC. Cardiovascular interventions 20090301
-
[Lymphoproliferative disorders after renal transplantation in a child].
Revista medica de Chile 20090301
-
Paclitaxel versus sirolimus stents in diabetic and nondiabetic patients.
Circulation. Cardiovascular quality and outcomes 20090301
-
Validation of anti-aging drugs by treating age-related diseases.
Aging 20090301
-
Target of rapamycin (TOR) mediates the transduction of nutritional signals into juvenile hormone production.
The Journal of biological chemistry 20090227
-
Progression of renal dysfunction in cardiac transplantation after the introduction of everolimus in the immunosuppressive regime.
Transplantation 20090227
-
Antiplatelet therapy and stent thrombosis after sirolimus-eluting stent implantation.
Circulation 20090224
-
2-year clinical outcomes after implantation of sirolimus-eluting, paclitaxel-eluting, and bare-metal coronary stents: results from the WDHR (Western Denmark Heart Registry).
Journal of the American College of Cardiology 20090224
-
Paclitaxel versus sirolimus: the battle is still ongoing.
Journal of the American College of Cardiology 20090224
-
Highly diastereoselective desymmetrisation of cyclic meso-anhydrides and derivatisation for use in natural product synthesis.
Organic & biomolecular chemistry 20090221
-
Zebrafish Tsc1 reveals functional interactions between the cilium and the TOR pathway.
Human molecular genetics 20090215
-
T cell dependence on mTOR signaling.
Cell cycle (Georgetown, Tex.) 20090215
-
Evaluation of mTOR function by a gain-of-function approach.
Cell cycle (Georgetown, Tex.) 20090215
-
Marked activity of irinotecan and rapamycin combination toward colon cancer cells in vivo and in vitro is mediated through cooperative modulation of the mammalian target of rapamycin/hypoxia-inducible factor-1alpha axis.
Clinical cancer research : an official journal of the American Association for Cancer Research 20090215
-
Not all substrates are treated equally: implications for mTOR, rapamycin-resistance and cancer therapy.
Cell cycle (Georgetown, Tex.) 20090215
-
Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation.
Journal of immunology (Baltimore, Md. : 1950) 20090215
-
Long-term outcomes of left main coronary intervention with drug-eluting stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090215
-
Long-term clinical outcomes after drug-eluting stent implantation in unprotected left main coronary artery disease.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090215
-
AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001.
Clinical cancer research : an official journal of the American Association for Cancer Research 20090215
-
A phase I trial to determine the safety, tolerability, and maximum tolerated dose of deforolimus in patients with advanced malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 20090215
-
Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20090211
-
Delivery of rapamycin to dendritic cells using degradable microparticles.
Journal of controlled release : official journal of the Controlled Release Society 20090210
-
Randomized comparison of everolimus-eluting and paclitaxel-eluting stents: two-year clinical follow-up from the Clinical Evaluation of the Xience V Everolimus Eluting Coronary Stent System in the Treatment of Patients with de novo Native Coronary Artery Lesions (SPIRIT) III trial.
Circulation 20090210
-
Coronary stent strut fracture after drug-eluting stent implantation: a newly recognized complication.
International journal of cardiology 20090206
-
Investigation of the regulation of transcriptional changes in Ancylostoma caninum larvae following serum activation, with a focus on the insulin-like signalling pathway.
Veterinary parasitology 20090205
-
Characterization of sirolimus metabolites in pediatric solid organ transplant recipients.
Pediatric transplantation 20090201
-
Synthesis of glycose carbamides and evaluation of the induction of erythroid differentiation of human erythroleukemic K562 cells.
European journal of medicinal chemistry 20090201
-
Complex functions of phosphatidylinositol 4,5-bisphosphate in regulation of TRPC5 cation channels.
Pflugers Archiv : European journal of physiology 20090201
-
Rapamycin in islet transplantation: friend or foe?
Transplant international : official journal of the European Society for Organ Transplantation 20090201
-
Adenovirus-mediated FKBP12.6 overexpression induces hypertrophy and apoptosis in cultured neonatal cardiomyocytes.
Clinical and experimental pharmacology & physiology 20090201
-
Sirolimus interacts with pathways essential for podocyte integrity.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090201
-
The pre-clinical assessment of rapamycin-eluting, durable polymer-free stent coating concepts.
Biomaterials 20090201
-
Sphingosine-1-phosphate induced mTOR-activation is mediated by the E3-ubiquitin ligase PAM.
Cellular signalling 20090201
-
IGF-I, EGF, and sex steroids regulate autophagy in bovine mammary epithelial cells via the mTOR pathway.
European journal of cell biology 20090201
-
Activation of the mammalian target of rapamycin signalling pathway in epidermal tumours and its correlation with cyclin-dependent kinase 2.
The British journal of dermatology 20090201
-
mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes.
American journal of physiology. Renal physiology 20090201
-
Inhibitory effect of rapamycin and dexamethasone on production of IL-17 and IFN-gamma in Vogt-Koyanagi-Harada patients.
The British journal of ophthalmology 20090201
-
Everolimus inhibits monocyte/macrophage migration in vitro and their accumulation in carotid lesions of cholesterol-fed rabbits.
The Journal of pharmacology and experimental therapeutics 20090201
-
Recent advances in neurobiology of Tuberous Sclerosis Complex.
Brain & development 20090201
-
The autophagic induction in Helicobacter pylori-infected macrophage.
Experimental biology and medicine (Maywood, N.J.) 20090201
-
Robust, high-throughput LC-MS/MS method for therapeutic drug monitoring of cyclosporine, tacrolimus, everolimus, and sirolimus in whole blood.
Therapeutic drug monitoring 20090201
-
Preventing the unfolded protein response via aberrant activation of 4E-binding protein 1 by versipelostatin.
Cancer science 20090201
-
mTOR regulates vascular smooth muscle cell differentiation from human bone marrow-derived mesenchymal progenitors.
Arteriosclerosis, thrombosis, and vascular biology 20090201
-
Blocking eukaryotic initiation factor 4F complex formation does not inhibit the mTORC1-dependent activation of protein synthesis in cardiomyocytes.
American journal of physiology. Heart and circulatory physiology 20090201
-
Impact of a prolonged delivery inflation time for optimal drug-eluting stent expansion.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090201
-
Targeting heat-shock protein 90 improves efficacy of rapamycin in a model of hepatocellular carcinoma in mice.
Hepatology (Baltimore, Md.) 20090201
-
LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection.
American journal of physiology. Heart and circulatory physiology 20090201
-
Belatacept as maintenance immunosuppression for postrenal transplant de novo drug-induced thrombotic microangiopathy.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090201
-
Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dependent and GCN2-independent pathways.
The FEBS journal 20090201
-
Pretreatment with insulin before ischaemia reduces infarct size in Langendorff-perfused rat hearts.
Acta physiologica (Oxford, England) 20090201
-
Metallothionein: a new soldier in the fight against chronic renal hypoxia?
Kidney international 20090201
-
Targeted therapy of human osteosarcoma with 17AAG or rapamycin: characterization of induced apoptosis and inhibition of mTOR and Akt/MAPK/Wnt pathways.
International journal of oncology 20090201
-
Laminar and compartmental regulation of dendritic growth in mature cortex.
Nature neuroscience 20090201
-
Inflation time and drug-eluting stent: the longer, the better..
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090201
-
Cost-effectiveness of drug-eluting stents including the economic impact of late stent thrombosis.
The American journal of cardiology 20090201
-
Comparison of the sirolimus-eluting versus paclitaxel-eluting coronary stent in patients with diabetes mellitus: the diabetes and drug-eluting stent (DiabeDES) randomized angiography trial.
The American journal of cardiology 20090201
-
In early-stage diabetic retinopathy, risk of cardiac events after implantation of sirolimus-eluting stent is higher than after coronary artery bypass surgery.
Journal of cardiology 20090201
-
Inhibition of class I phosphoinositide 3-kinase activity impairs proliferation and triggers apoptosis in acute promyelocytic leukemia without affecting atra-induced differentiation.
Cancer research 20090201
-
The protein kinase Tor1 regulates adhesin gene expression in Candida albicans.
PLoS pathogens 20090201
-
Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.
PLoS biology 20090201
-
Common variable immunodeficiency with regulatory T-cell deficiency treated with rapamycin.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20090201
-
Activation of the AKT and mammalian target of rapamycin pathways and the inhibitory effects of rapamycin on those pathways in canine malignant melanoma cell lines.
American journal of veterinary research 20090201
-
Multiple spontaneous coronary artery dissection associated with a left main coronary artery lesion treated by stenting. Late multiple stent fractures detected by multislice CT.
Revista espanola de cardiologia 20090201
-
FKBP12 depletion leads to loss of sarcoplasmic reticulum Ca(2+) stores in rat vas deferens.
Journal of pharmacological sciences 20090201
-
mTOR-blocking agents in advanced renal cancer: an emerging therapeutic option.
Expert opinion on investigational drugs 20090201
-
Interaction with phosphoinositides confers adaptation onto the TRPV1 pain receptor.
PLoS biology 20090201
-
Tacrolimus pharmacokinetic drug interactions: effect of prednisone, mycophenolic acid or sirolimus.
Fundamental & clinical pharmacology 20090201
-
Optical coherence tomography to diagnose under-expansion of a drug-eluting stent.
JACC. Cardiovascular imaging 20090201
-
Clinical and angiographic outcomes with sirolimus-eluting stents in total coronary occlusions: the ACROSS/TOSCA-4 (Approaches to Chronic Occlusions With Sirolimus-Eluting Stents/Total Occlusion Study of Coronary Arteries-4) trial.
JACC. Cardiovascular interventions 20090201
-
[The effect of rapamycin liposome gutta inhibiting rat corneal neovascularization].
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20090201
-
Randomized comparison of coronary bifurcation stenting with the crush versus the culotte technique using sirolimus eluting stents: the Nordic stent technique study.
Circulation. Cardiovascular interventions 20090201
-
Novel role of the CXC chemokine receptor 3 in inflammatory response to arterial injury: involvement of mTORC1.
Circulation research 20090130
-
The Rheb-mTOR pathway is upregulated in reactive astrocytes of the injured spinal cord.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20090128
-
Safety and pharmacokinetics of paclitaxel and the oral mTOR inhibitor everolimus in advanced solid tumours.
British journal of cancer 20090127
-
Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53.
British journal of cancer 20090127
-
What does the CONVERT trial really tell us about conversion from calcineurin inhibitors to sirolimus?
Transplantation 20090127
-
Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial.
Transplantation 20090127
-
A systematic approach to minimizing wound problems for de novo sirolimus-treated kidney transplant recipients.
Transplantation 20090127
-
LKB1/KRAS mutant lung cancers constitute a genetic subset of NSCLC with increased sensitivity to MAPK and mTOR signalling inhibition.
British journal of cancer 20090127
-
One year clinical and six month angiographic results of drug eluting stents for ST elevation acute myocardial infarction: 'real world' comparison between sirolimus- and paclitaxel-eluting stents.
International journal of cardiology 20090124
-
Rapamycin-induced Gln3 dephosphorylation is insufficient for nuclear localization: Sit4 and PP2A phosphatases are regulated and function differently.
The Journal of biological chemistry 20090123
-
[SORT OUT II--a randomized study of drug-eluting coronary stents--secondary publication].
Ugeskrift for laeger 20090119
-
Three-year survival following multivessel percutaneous coronary intervention with bare-metal or drug-eluting stents in unselected patients.
The American journal of cardiology 20090115
-
Inhibition of mTOR radiosensitizes soft tissue sarcoma and tumor vasculature.
Clinical cancer research : an official journal of the American Association for Cancer Research 20090115
-
Oral mTOR inhibitor everolimus in patients with gemcitabine-refractory metastatic pancreatic cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090110
-
Clinical characteristics of stent fracture after sirolimus-eluting stent implantation.
International journal of cardiology 20090109
-
Biomedicine. A new view on--and hope for--an old disease.
Science (New York, N.Y.) 20090109
-
Biomedicine. A discriminating killer.
Science (New York, N.Y.) 20090109
-
New uracil dimers showing erythroid differentiation inducing activities.
Journal of medicinal chemistry 20090108
-
Glycemic control in patients with insulinoma treated with everolimus.
The New England journal of medicine 20090108
-
Randomized study of the crush technique versus provisional side-branch stenting in true coronary bifurcations: the CACTUS (Coronary Bifurcations: Application of the Crushing Technique Using Sirolimus-Eluting Stents) Study.
Circulation 20090106
-
SP600125 negatively regulates the mammalian target of rapamycin via ATF4-induced Redd1 expression.
FEBS letters 20090105
-
Rapamycin instead of mycophenolate mofetil or azathioprine in treatment of post-renal transplantation urothelial carcinoma.
Chinese medical journal 20090105
-
Clinical outcomes of serolimus-eluting stents versus bare metal stents in ST-segment elevation myocardial infarction patients: a meta-analysis.
Chinese medical journal 20090105
-
[Current concepts and treatment advances in systemic mastocytosis].
La Revue de medecine interne 20090101
-
Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies.
Cell death and differentiation 20090101
-
Moderate-severe renal insufficiency is a risk factor for sirolimus-eluting stent thrombosis. The RIFT study.
Cardiology 20090101
-
Multigene targeting of signal transduction pathways for the treatment of breast and prostate tumors: comparison between combination therapies employing bispecific oligonucleotides with either Rapamycin or Paclitaxel.
Medical oncology (Northwood, London, England) 20090101
-
Minimization protocols in pancreas transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20090101
-
Immunosuppression without calcineurin inhibition: optimization of renal function in expanded criteria donor renal transplantation.
Clinical transplantation 20090101
-
Metabolic control of T cell activation and death in SLE.
Autoimmunity reviews 20090101
-
Steroid withdrawal five days after renal transplantation allows for the prevention of wound-healing complications associated with sirolimus therapy.
Clinical transplantation 20090101
-
Influence of HLA disparity, immunosuppressive regimen used, and type of kidney allograft on production of anti-HLA class-I antibodies after transplant and occurrence of rejection.
Immunopharmacology and immunotoxicology 20090101
-
Activation of HIF-1alpha in exponentially growing cells via hypoxic stimulation is independent of the Akt/mTOR pathway.
Journal of cellular physiology 20090101
-
Different profile of gene expression of cytokines in peripheral blood mononuclear cells of transplant recipients treated with m-TOR inhibitor and calcineurin inhibitor.
Transplant immunology 20090101
-
The characteristics and in vivo suppression of neointimal formation with sirolimus-eluting polymeric stents.
Biomaterials 20090101
-
The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway.
Human molecular genetics 20090101
-
Rapamycin attenuates the severity of murine adriamycin nephropathy.
American journal of nephrology 20090101
-
Calcineurin-inhibitor minimization protocols in heart transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20090101
-
Portal venous donor-specific transfusion in conjunction with sirolimus prolongs renal allograft survival in nonhuman primates.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090101
-
Mechanisms behind the synergistic effect of sirolimus and imatinib in preventing restenosis after intimal injury.
Journal of vascular research 20090101
-
Regulation of placental amino acid transporter activity by mammalian target of rapamycin.
American journal of physiology. Cell physiology 20090101
-
Treatment of refractory oral erosive lichen planus with topical rapamycin: 7 cases.
Dermatology (Basel, Switzerland) 20090101
-
Significant association of coronary stent fracture with in-stent restenosis in sirolimus-eluting stents.
Coronary artery disease 20090101
-
Limited utility of rapamycin in severe, refractory Wegener's granulomatosis.
The Journal of rheumatology 20090101
-
Impact of direct sirolimus-eluting stent implantation on the early systemic inflammatory response compared with complementary stent implantation.
Coronary artery disease 20090101
-
Use of rapamycin in the induction of tolerogenic dendritic cells.
Handbook of experimental pharmacology 20090101
-
Inhibition of human immunodeficiency virus (HIV-1) infection in human peripheral blood leucocytes-SCID reconstituted mice by rapamycin.
Clinical and experimental immunology 20090101
-
Three-year clinical outcome after primary stenting of totally occluded native coronary arteries: a randomized comparison of bare-metal stent implantation with sirolimus-eluting stent implantation for the treatment of total coronary occlusions (Primary Stenting of Totally Occluded Native Coronary Arteries [PRISON] II study).
American heart journal 20090101
-
Multicenter international registry of unprotected left main coronary artery percutaneous coronary intervention with drug-eluting stents in patients with myocardial infarction.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101
-
Percutaneous revascularization of the 'unprotected' left main during acute myocardial infarction: 'Dare to struggle! Dare to win!'.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101
-
Analysis of left main coronary artery bifurcation lesions treated with biolimus-eluting DEVAX AXXESS plus nitinol self-expanding stent: intravascular ultrasound results of the AXXENT trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101
-
Treating the left main bifurcation lesion: the 'three stent solution'.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101
-
Multiple stent fractures at the site of coronary artery bypass insertion.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101
-
Coronary stent fracture: the hidden truth of a problem more common than stent thrombosis.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101
-
Assessment with optical coherence tomography of a new strategy for bifurcational lesion treatment: the Tryton Side-Branch Stent.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101
-
Step-by-step StentBoost-guided small vessel stenting using the self-expandable Sparrow stent-in-wire.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101
-
Urine metabolites reflect time-dependent effects of cyclosporine and sirolimus on rat kidney function.
Chemical research in toxicology 20090101
-
Sirolimus treatment for recurrent lymphangioleiomyomatosis after lung transplantation.
The Annals of thoracic surgery 20090101
-
Characterization of the effects and functions of sumoylation through rapamycin-mediated heterodimerization.
Methods in molecular biology (Clifton, N.J.) 20090101
-
San Antonio Breast Cancer Symposium.
The Lancet. Oncology 20090101
-
Distinct roles for mammalian target of rapamycin complexes in the fibroblast response to transforming growth factor-beta.
Cancer research 20090101
-
Therapeutic strategy targeting the mTOR-HIF-1alpha-VEGF pathway in ovarian clear cell adenocarcinoma.
Pathology international 20090101
-
Photodynamic therapy targets the mTOR signaling network in vitro and in vivo.
Molecular pharmaceutics 20090101
-
[Effect of Rapamycin and Cyclosporin A on the expression of TLR5 and Foxp3 in allorejection].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20090101
-
Effect of sirolimus on urinary bladder cancer T24 cell line.
Journal of experimental & clinical cancer research : CR 20090101
-
Sera from patients with diabetes do not alter the effect of mammalian target of rapamycin inhibition on smooth muscle cell proliferation.
Journal of cardiovascular pharmacology 20090101
-
Everolimus-associated pneumonitis in 3 heart transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20090101
-
Graft-versus-host disease prophylaxis with everolimus and tacrolimus is associated with a high incidence of sinusoidal obstruction syndrome and microangiopathy: results of the EVTAC trial.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090101
-
Rapamycin for chemoprevention of upper aerodigestive tract cancers.
Cancer prevention research (Philadelphia, Pa.) 20090101
-
Targeting mammalian target of rapamycin by rapamycin prevents tumor progression in an oral-specific chemical carcinogenesis model.
Cancer prevention research (Philadelphia, Pa.) 20090101
-
Regulation of D-cyclin translation inhibition in myeloma cells treated with mammalian target of rapamycin inhibitors: rationale for combined treatment with extracellular signal-regulated kinase inhibitors and rapamycin.
Molecular cancer therapeutics 20090101
-
Bone growth during rapamycin therapy in young rats.
BMC pediatrics 20090101
-
mTOR in growth and protection of hypertrophying myocardium.
Cardiovascular & hematological agents in medicinal chemistry 20090101
-
Recent patents and patent applications relating to mTOR pathway.
Recent patents on DNA & gene sequences 20090101
-
Inhibition of autophagy causes tau proteolysis by activating calpain in rat brain.
Journal of Alzheimer's disease : JAD 20090101
-
Conditional nuclear import and export of yeast proteins using a chemical inducer of dimerization.
Cell biochemistry and biophysics 20090101
-
The pharmacodynamic effect of sirolimus: individual variation of cytokine mRNA expression profiles in human whole blood samples.
Immunobiology 20090101
-
Comparison of bare metal stent with pioglitazone versus sirolimus-eluting stent for percutaneous coronary intervention in patients with Type 2 diabetes mellitus.
Cardiovascular revascularization medicine : including molecular interventions 20090101
-
Extremely late drug-eluting stent thrombosis: 2037 days after deployment.
Cardiovascular revascularization medicine : including molecular interventions 20090101
-
[Assessment of the course of ischemic heart disease after placement of stents with drug covering and uncovered metal stents: data of 3 years follow-up].
Kardiologiia 20090101
-
Temsirolimus in patients with advanced renal cell carcinoma: an overview.
Advances in therapy 20090101
-
Metastatic renal cell cancer treatments: an indirect comparison meta-analysis.
BMC cancer 20090101
-
[Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma].
Aktuelle Urologie 20090101
-
Sirolimus-based rescue therapy after rejection in liver transplantation.
Clinical transplantation 20090101
-
Cyclosporin A, but not everolimus, inhibits DNA repair in human fibroblasts and lymphoblasts.
International journal of clinical pharmacology and therapeutics 20090101
-
Total synthesis of rapamycin.
Chemistry (Weinheim an der Bergstrasse, Germany) 20090101
-
Conversion to sirolimus with calcineurin inhibitor elimination vs. dose minimization and renal outcome in heart and lung transplant recipients.
Clinical transplantation 20090101
-
[Topics in mTOR pathway and its inhibitors].
Bulletin du cancer 20090101
-
Temsirolimus-induced glomerulopathy.
Oncology 20090101
-
Phase I study combining treatment with temsirolimus and sunitinib malate in patients with advanced renal cell carcinoma.
Clinical genitourinary cancer 20090101
-
Chest pain without significant coronary stenosis after implantation of sirolimus-eluting stents.
Internal medicine (Tokyo, Japan) 20090101
-
Effect of temsirolimus versus interferon-alpha on outcome of patients with advanced renal cell carcinoma of different tumor histologies.
Medical oncology (Northwood, London, England) 20090101
-
Depletion of kinesin 5B affects lysosomal distribution and stability and induces peri-nuclear accumulation of autophagosomes in cancer cells.
PloS one 20090101
-
No in vivo infection of triple immunosuppressed non-human primates after inoculation with high titers of porcine endogenous retroviruses.
Xenotransplantation 20090101
-
Survival benefit in heart transplant recipients who have coronary artery disease confirmed using angiography and are receiving sirolimus.
Transplantation proceedings 20090101
-
Rapamycin induces autophagy in islets: relevance in islet transplantation.
Transplantation proceedings 20090101
-
Effects of systemic immunosuppression on islet engraftment and function into a subcutaneous biocompatible device.
Transplantation proceedings 20090101
-
Effect of low-dose rapamycin on tumor growth in two human hepatocellular cancer cell lines.
Transplantation proceedings 20090101
-
Effect of liver regeneration on the pharmacokinetics of immunosuppressive drugs.
Transplantation proceedings 20090101
-
Rapamycin promotes the enrichment of CD4(+)CD25(hi)FoxP3(+) T regulatory cells from naïve CD4(+) T cells of baboon that suppress antiporcine xenogenic response in vitro.
Transplantation proceedings 20090101
-
Sirolimus for rescue of steroid and anti-thymocyte globulin-resistant recurrent acute rejection after liver transplantation: report of one case.
Transplantation proceedings 20090101
-
Late conversion to everolimus complicated with necrotizing glomerulonephritis in a renal allograft recipient: case report.
Transplantation proceedings 20090101
-
Activated mammalian target of rapamycin is associated with T regulatory cell insufficiency in nasal polyps.
Respiratory research 20090101
-
[A case of Kaposi's sarcoma in the rapamycin era].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20090101
-
Low coronary flow velocity and shear stress predict restenosis after sirolimus-eluting stent implantation.
Scandinavian cardiovascular journal : SCJ 20090101
-
Everolimus in liver and lung transplantation.
Drugs of today (Barcelona, Spain : 1998) 20090101
-
The gender paradox.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101
-
Observational studies of drug-eluting stents--some are more equal than others.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101
-
Assessment of the absorption process following bioabsorbable everolimus-eluting stent implantation: temporal changes in strain values and tissue composition using intravascular ultrasound radiofrequency data analysis. A substudy of the ABSORB clinical trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101
-
Long-term follow-up of percutaneous coronary intervention of unprotected left main lesions with drug eluting stents: predictors of clinical outcome.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101
-
The relative safety and efficacy of bare-metal and drug-eluting stents in low and high-risk patient subsets. An epidemiological analysis of three sequential cohorts of consecutive all comers (n = 6129).
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101
-
Effect of gender differences on early and mid-term clinical outcome after percutaneous or surgical coronary revascularisation in patients with multivessel coronary artery disease: insights from ARTS I and ARTS II.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101
-
In vivo evaluation of a biolimus eluting nickel titanium self expanding stent with overlapping balloon expandable drug eluting and bare metal stents in a porcine coronary model.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101
-
Metabolic profiles in urine reflect nephrotoxicity of sirolimus and cyclosporine following rat kidney transplantation.
Nephron. Experimental nephrology 20090101
-
Conditional protein stabilization via the small molecules Shld-1 and rapamycin increases the signal-to-noise ratio with tet-inducible gene expression.
BioTechniques 20090101
-
Glucose amplifies fatty acid-induced endoplasmic reticulum stress in pancreatic beta-cells via activation of mTORC1.
PloS one 20090101
-
A rapid HPLC-MS/MS method for the simultaneous quantification of cyclosporine A, tacrolimus, sirolimus and everolimus in human blood samples.
Nature protocols 20090101
-
A central role for Foxp3+ regulatory T cells in K-Ras-driven lung tumorigenesis.
PloS one 20090101
-
Testing intravitreal toxicity of rapamycin in rabbit eyes.
Arquivos brasileiros de oftalmologia 20090101
-
Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models.
BMC pharmacology 20090101
-
Ligand-regulated peptide aptamers.
Methods in molecular biology (Clifton, N.J.) 20090101
-
Systemic chemoprevention.
Cancer treatment and research 20090101
-
Larger dosage required for everolimus than sirolimus to maintain same blood concentration in two pancreatic islet transplant patients with tacrolimus.
Drug metabolism and pharmacokinetics 20090101
-
Fibrocyte CXCR4 regulation as a therapeutic target in pulmonary fibrosis.
The international journal of biochemistry & cell biology 20090101
-
[Targeting of the AKT-mTOR pathway in head and neck and lung cancer].
Bulletin du cancer 20090101
-
Diabetes mellitus: a prothrombotic state implications for outcomes after coronary revascularization.
Vascular health and risk management 20090101
-
Interferon-alpha-induced mTOR activation is an anti-hepatitis C virus signal via the phosphatidylinositol 3-kinase-Akt-independent pathway.
Journal of gastroenterology 20090101
-
Rapamycin inhibits growth of cholangiocarcinoma cells.
Hepato-gastroenterology 20090101
-
A kinase-dead knock-in mutation in mTOR leads to early embryonic lethality and is dispensable for the immune system in heterozygous mice.
BMC immunology 20090101
-
Sirolimus-eluting stents or vascular brachytherapy for in-stent restenosis after 3-year follow-up of the SISR (Sirolimus-Eluting Stent Versus Vascular Brachytherapy for In-Stent Restenosis) trial: a call for caution?
JACC. Cardiovascular interventions 20090101
-
Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia.
Disease models & mechanisms 20090101
-
Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells.
BMC cancer 20090101
-
Relationship between renal resistance index and renal function in liver transplant recipients after cessation of calcineurin inhibitor.
Clinical transplantation 20090101
-
The influence of commonly used immunosuppressive drugs on the small bowel functions - a comparative experimental study.
Annals of transplantation 20090101
-
Current status and challenges associated with targeting mTOR for cancer therapy.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20090101
-
Management of metabolic cytochrome P450 3A4 drug-drug interaction between everolimus and azole antifungals in a renal transplant patient.
Clinical drug investigation 20090101
-
Formalin-induced behavioural hypersensitivity and neuronal hyperexcitability are mediated by rapid protein synthesis at the spinal level.
Molecular pain 20090101
-
Different effects of FK506, rapamycin, and mycophenolate mofetil on glucose-stimulated insulin release and apoptosis in human islets.
Cell transplantation 20090101
-
Equivalent benefit of mTORC1 blockade and combined PI3K-mTOR blockade in a mouse model of tuberous sclerosis.
Molecular cancer 20090101
-
[Long-term results of coronary endovascular revascularisation with sirolimus-eluting stents in patients with ischemic heart disease comorbid with type-2 diabetes mellitus: data from 18-month prospective study].
Terapevticheskii arkhiv 20090101
-
Differential responses of human regulatory T cells (Treg) and effector T cells to rapamycin.
PloS one 20090101
-
New approach for local delivery of rapamycin by bioadhesive PLGA-carbopol nanoparticles.
Drug delivery 20090101
-
Noninvasive evaluation of coronary endothelial function following sirolimus-eluting stent implantation by using positron emission tomography.
Cardiology 20090101
-
There is a choice for immunosuppressive drug nephrotoxicity: Is it time to change?
Journal of nephrology 20090101
-
Cost effectiveness of sirolimus-eluting stents compared with bare metal stents in acute myocardial infarction: insights from the TYPHOON trial.
Applied health economics and health policy 20090101
-
Methods for analysis of brain tumor stem cell and neural stem cell self-renewal.
Methods in molecular biology (Clifton, N.J.) 20090101
-
Transport-metabolism interplay: LXRalpha-mediated induction of human ABC transporter ABCC2 (cMOAT/MRP2) in HepG2 cells.
Molecular pharmaceutics 20090101
-
Human protein phosphatase PP6 regulatory subunits provide Sit4-dependent and rapamycin-sensitive sap function in Saccharomyces cerevisiae.
PloS one 20090101
-
[Economic evaluation and budget impact analysis of the Endeavor drug-eluting stent in Spain].
Gaceta sanitaria 20090101
-
Optimizing immunosuppression with sirolimus in the first year posttransplantation: experience in the United States.
Transplantation proceedings 20090101
-
Where did we leave off in 2008? Conclusions from the 8th International Symposium.
Transplantation proceedings 20090101
-
Reducing the risk of left ventricular hypertrophy in kidney transplant recipients: the potential role of mammalian target of rapamycin.
Transplantation proceedings 20090101
-
New approaches to de novo immunosuppression and steroid elimination.
Transplantation proceedings 20090101
-
De novo immunosuppression with mammalian target of rapamycin inhibitors and posttransplantation malignancy in focus.
Transplantation proceedings 20090101
-
[Association between late incomplete stent apposition after sirolimus eluting stent implantation and clinical outcomes in patients with acute coronary syndrome].
Zhonghua xin xue guan bing za zhi 20090101
-
Timing of sirolimus conversion influences recovery of renal function in liver transplant recipients.
Clinical transplantation 20090101
-
Combination of everolimus and tacrolimus in kidney transplant patients with intolerance to mycophenolate mofetil/mycophenolic acid.
Transplantation proceedings 20090101
-
De novo kidney transplant recipients need higher doses of Advagraf compared with Prograf to get therapeutic levels.
Transplantation proceedings 20090101
-
Conversion to everolimus in kidney transplant recipients with decreased renal function.
Transplantation proceedings 20090101
-
Evaluation of the efficacy and safety of conversion to sirolimus in 85 renal transplant recipients.
Transplantation proceedings 20090101
-
Sirolimus and everolimus induced pneumonitis in adult renal allograft recipients: experience in a center.
Transplantation proceedings 20090101
-
Indications and management of everolimus after liver transplantation.
Transplantation proceedings 20090101
-
Efficacy, tolerance, and safety of mammalian target of rapamycin inhibitors as rescue immunosuppressants in liver transplantation.
Transplantation proceedings 20090101
-
Everolimus represents an advance in immunosuppression for patients who have developed cancer after renal transplantation.
Transplantation proceedings 20090101
-
Switching to sirolimus in renal transplant recipients with hepatitis C virus: a safe option.
Transplantation proceedings 20090101
-
Similar lipid profile but improved long-term outcomes with sirolimus after cyclosporine withdrawal compared to sirolimus with continuous cyclosporine.
Transplantation proceedings 20090101
-
Complete switch to everolimus in long-term kidney transplants: evolution of the renal function.
Transplantation proceedings 20090101
-
Clinical implications of proteinuria in renal transplant recipients switching to rapamycin for chronic allograft dysfunction.
Transplantation proceedings 20090101
-
Monotherapy rapamycin in renal transplant recipients with lymphoma successfully treated with rituximab.
Transplantation proceedings 20090101
-
FTY720 and everolimus in de novo renal transplant patients at risk for delayed graft function: results of an exploratory one-yr multicenter study.
Clinical transplantation 20090101
-
Chronic allograft nephropathy--a clinical syndrome: early detection and the potential role of proliferation signal inhibitors.
Clinical transplantation 20090101
-
Stent thrombosis four and a half years after implantation of a sirolimus-eluting stent.
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20090101
-
Post-transplantation malignancy: a cell autonomous mechanism with implications for therapy.
Transactions of the American Clinical and Climatological Association 20090101
-
Interstitial pneumonitis in the transplant patient: consider sirolimus-associated pulmonary toxicity.
The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society 20090101
-
The rapamycin-regulated gene expression signature determines prognosis for breast cancer.
Molecular cancer 20090101
-
Comparative analysis of neointimal coverage with paclitaxel and zotarolimus drug-eluting stents, using optical coherence tomography 6 months after implantation.
Archives of cardiovascular diseases 20090101
-
New therapeutic approaches in the management of metastatic renal cell carcinoma.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20090101
-
Can proliferation signal inhibitor-induced Tregs really reflect transplantation tolerance in clinical solid organ transplantation?
International reviews of immunology 20090101
-
Effects of everolimus on cytokines, oxidative stress, and renal histology in ischemia-reperfusion injury of the kidney.
Renal failure 20090101
-
Multiple coronary artery aneurysm formation one year and four years after sirolimus-eluting coronary stent implantation.
Cardiovascular revascularization medicine : including molecular interventions 20090101
-
Rapamycin response in tumorigenic and non-tumorigenic hepatic cell lines.
PloS one 20090101
-
Limited sampling models and Bayesian estimation for mycophenolic acid area under the curve prediction in stable renal transplant patients co-medicated with ciclosporin or sirolimus.
Clinical pharmacokinetics 20090101
-
[Pneumonitis caused by sirolimus: improvement after switching to everolimus].
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20090101
-
[The influence of coronary stenting with rapamycin-eluting stents on the number of circulating CD4+CD25high+regulatory T-cells].
Terapevticheskii arkhiv 20090101
-
Rapid modification of proteins using a rapamycin-inducible tobacco etch virus protease system.
PloS one 20090101
-
Malignant epithelioid angiomyolipoma in the kidney and liver of a patient with pulmonary lymphangioleiomyomatosis: lack of response to sirolimus.
Internal medicine (Tokyo, Japan) 20090101
-
Development and characterization of liposomal formulations for rapamycin delivery and investigation of their antiproliferative effect on MCF7 cells.
Journal of liposome research 20090101
-
Induction of granzyme B expression in T-cell receptor/CD28-stimulated human regulatory T cells is suppressed by inhibitors of the PI3K-mTOR pathway.
BMC immunology 20090101
-
Conversion from cyclosporin A to sirolimus retards the progression of chronic allograft nephropathy in the long term in a rat kidney transplantation model.
The Journal of international medical research 20090101
-
mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells.
Science signaling 20090101
-
[Acute renal failure in a patient with renal carcinoma treated with temsirolimus].
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20090101
-
Adherence must always be considered: is everolimus really ineffective as a treatment for atopic dermatitis?
The Journal of dermatological treatment 20090101
-
Severe atopic dermatitis treated with everolimus.
The Journal of dermatological treatment 20090101
-
Repeated plaque prolapse after sirolimus-eluting stent implantation in the treatment of chronic total occlusion lesion.
Acute cardiac care 20090101
-
Inhibition of mTOR Activates the MAPK Pathway in Glioblastoma Multiforme.
Cancer genomics & proteomics 20090101
-
Controversies in breast cancer: the mammalian target of rapamycin as a target for breast cancer therapy.
Breast cancer research : BCR 20090101
-
Update on the everolimus-eluting coronary stent system: results and implications from the SPIRIT clinical trial program.
Vascular health and risk management 20090101
-
Combined effect of rapamycin and cisplatin on survival of Hep-2 cells in vitro.
Oncology research 20090101
-
Fracture of zotarolimus-eluting stent after implantation.
Texas Heart Institute journal 20090101
-
Mycophenolate mofetil versus Rapamycin in Han: SPRD rats with Polycystic Kidney Disease.
Biological research 20090101
-
Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density.
Aging 20090101
-
Rapamycin does not adversely affect intrahepatic islet engraftment in mice and improves early islet engraftment in humans.
Islets 20090101
-
Islet transplantation with alemtuzumab induction and calcineurin-free maintenance immunosuppression results in improved short- and long-term outcomes.
Transplantation 20081227
-
Safety and efficacy of statin therapy in patients switched from cyclosporine a to sirolimus after cardiac transplantation.
Transplantation 20081227
-
Rapamycin reverses TLR4 signaling-triggered tumor apoptosis resistance by disrupting Akt-mediated Bcl-xL upregulation.
International immunopharmacology 20081220
-
Acute coronary syndrome is an independent risk factor for late incomplete stent apposition after sirolimus-eluting stent implantation.
Chinese medical journal 20081220
-
Treatment of diffuse in-stent restenosis with drug-eluting stents vs. intracoronary beta-radiation therapy: INDEED Study.
International journal of cardiology 20081217
-
Endothelialization and late stent thrombosis in diabetics.
Journal of the American College of Cardiology 20081216
-
mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).
The Biochemical journal 20081215
-
Mass balance in rapamycin autoxidation.
Journal of pharmaceutical and biomedical analysis 20081215
-
Overview of the 2007 Food and Drug Administration Circulatory System Devices Panel meeting on the Xience V Everolimus-Eluting Coronary Stent.
The American journal of cardiology 20081215
-
Inhibition of Mammalian target of rapamycin by rapamycin causes the regression of carcinogen-induced skin tumor lesions.
Clinical cancer research : an official journal of the American Association for Cancer Research 20081215
-
Deconstructing feedback-signaling networks to improve anticancer therapy with mTORC1 inhibitors.
Cell cycle (Georgetown, Tex.) 20081215
-
Differential dependence of hypoxia-inducible factors 1 alpha and 2 alpha on mTORC1 and mTORC2.
The Journal of biological chemistry 20081212
-
Improved survival in lymphoma patients receiving sirolimus for graft-versus-host disease prophylaxis after allogeneic hematopoietic stem-cell transplantation with reduced-intensity conditioning.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081210
-
Multivessel coronary revascularization in patients with and without diabetes mellitus: 3-year follow-up of the ARTS-II (Arterial Revascularization Therapies Study-Part II) trial.
Journal of the American College of Cardiology 20081209
-
Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis.
Cancer cell 20081209
-
Recovery of tacrolimus-associated brachial neuritis after conversion to everolimus in a pediatric renal transplant recipient--case report and review of the literature.
Pediatric transplantation 20081201
-
Involvement of the TGF-beta and mTOR/p70S6Kinase pathways in the transformation process induced by v-ErbA.
Leukemia research 20081201
-
Induction of HIF-1alpha expression by intermittent hypoxia: involvement of NADPH oxidase, Ca2+ signaling, prolyl hydroxylases, and mTOR.
Journal of cellular physiology 20081201
-
Low viral load post-transplant lymphoproliferative disease localized within the tongue.
Transplant infectious disease : an official journal of the Transplantation Society 20081201
-
Sirolimus in unmanipulated haploidentical cell transplantation.
Bone marrow transplantation 20081201
-
Rheb activates protein synthesis and growth in adult rat ventricular cardiomyocytes.
Journal of molecular and cellular cardiology 20081201
-
Genome-wide expression analysis reveals TORC1-dependent and -independent functions of Sch9.
FEMS yeast research 20081201
-
Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury.
Neurobiology of disease 20081201
-
Sirolimus is associated with veno-occlusive disease of the liver after myeloablative allogeneic stem cell transplantation.
Blood 20081201
-
Blockade of mTOR signaling potentiates the ability of histone deacetylase inhibitor to induce growth arrest and differentiation of acute myelogenous leukemia cells.
Leukemia 20081201
-
Exploring the role of novel agents in the treatment of renal cell carcinoma.
Cancer treatment reviews 20081201
-
ERK and p38 pathways regulate amino acid signalling.
Biochimica et biophysica acta 20081201
-
Phosphorylation of eIF4E by MNKs supports protein synthesis, cell cycle progression and proliferation in prostate cancer cells.
Carcinogenesis 20081201
-
Ethylenecarbodiimide-coupled allogeneic antigen presenting cells induce human CD4+ regulatory T cells.
Clinical immunology (Orlando, Fla.) 20081201
-
Randomized trial on routine vs. provisional T-stenting in the treatment of de novo coronary bifurcation lesions.
European heart journal 20081201
-
The effect of sirolimus on prostate-specific antigen (PSA) levels in male renal transplant recipients without prostate cancer.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20081201
-
CD8+ T-Cell depletion and rapamycin synergize with combined coreceptor/stimulation blockade to induce robust limb allograft tolerance in mice.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20081201
-
ABT-869, a multi-targeted tyrosine kinase inhibitor, in combination with rapamycin is effective for subcutaneous hepatocellular carcinoma xenograft.
Journal of hepatology 20081201
-
Laryngeal transplantation in the setting of cancer: a rat model.
The Laryngoscope 20081201
-
Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.
Rapid communications in mass spectrometry : RCM 20081201
-
Temsirolimus in patients with renal cancer on hemodialysis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081201
-
Overcoming mTOR inhibition-induced paradoxical activation of survival signaling pathways enhances mTOR inhibitors' anticancer efficacy.
Cancer biology & therapy 20081201
-
Ocular toxicity and distribution of subconjunctival and intravitreal rapamycin in horses.
Journal of veterinary pharmacology and therapeutics 20081201
-
Culotte stenting technique in coronary bifurcation disease: angiographic follow-up using dedicated quantitative coronary angiographic analysis and 12-month clinical outcomes.
European heart journal 20081201
-
Deforolimus (AP23573) a novel mTOR inhibitor in clinical development.
Expert opinion on investigational drugs 20081201
-
Regulation of adiponectin secretion by insulin and amino acids in 3T3-L1 adipocytes.
Metabolism: clinical and experimental 20081201
-
The pharmacokinetics of Biolimus A9 after elution from the Nobori stent in patients with coronary artery disease: the NOBORI PK study.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081201
-
Inhibition of the alloimmune response through the generation of regulatory T cells by a MHC class II-derived peptide.
Journal of immunology (Baltimore, Md. : 1950) 20081201
-
CD40-induced signaling in human endothelial cells results in mTORC2- and Akt-dependent expression of vascular endothelial growth factor in vitro and in vivo.
Journal of immunology (Baltimore, Md. : 1950) 20081201
-
Insulin-like growth factor stimulation increases radiosensitivity of a pancreatic cancer cell line through endoplasmic reticulum stress under hypoxic conditions.
Cancer science 20081201
-
LC3-I conversion to LC3-II does not necessarily result in complete autophagy.
International journal of molecular medicine 20081201
-
Is there a preferable DES in diabetic patients? A critical appraisal of the evidence.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081201
-
Sirolimus ameliorated post lung transplant chylothorax in lymphangioleiomyomatosis.
The Annals of thoracic surgery 20081201
-
Treatment for genetic diseases.
Current opinion in pediatrics 20081201
-
Incidence of bleeding and compliance on prolonged dual antiplatelet therapy (aspirin + thienopyridine) following drug-eluting stent implantation.
The American journal of cardiology 20081201
-
Very late thrombosis of sirolimus-eluting stent due to late malapposition: serial observations with optical coherence tomography.
Journal of cardiology 20081201
-
A whole-animal microplate assay for metabolic rate using zebrafish.
Journal of biomolecular screening 20081201
-
Autophagy-induced tumor dormancy in ovarian cancer.
The Journal of clinical investigation 20081201
-
The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells.
The Journal of clinical investigation 20081201
-
Rapamycin shows anticancer activity in primary chronic lymphocytic leukemia cells in vitro, as single agent and in drug combination.
Leukemia & lymphoma 20081201
-
Formalin can alter the intracellular localization of some transcription factors in Saccharomyces cerevisiae.
FEMS yeast research 20081201
-
Endothelialization of sirolimus-eluting stents with slow and extended drug release in the porcine overstretch model.
The Journal of invasive cardiology 20081201
-
Proliferation signal inhibitor-induced decrease of vascular endothelial cadherin expression and increase of endothelial permeability in vitro are prevented by an anti-oxidant.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20081201
-
Epstein-Barr virus, rapamycin, and host immune responses.
Current opinion in organ transplantation 20081201
-
In vivo characterization of a polymeric nanoparticle platform with potential oral drug delivery capabilities.
Molecular cancer therapeutics 20081201
-
Re: 'midterm results of a sirolimus-eluting stent implanted for recurrent carotid in-stent restenosis'.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20081201
-
[Everolimus (RAD001) and solid tumours: a 2008 summary].
Bulletin du cancer 20081201
-
Therapeutic effect of Tripterygium wilfordii on proteinuria associated with sirolimus in renal transplant recipients.
Transplantation proceedings 20081201
-
Sirolimus-based immunosuppression therapy in liver transplantation for patients with hepatocellular carcinoma exceeding the Milan criteria.
Transplantation proceedings 20081201
-
Conversion to sirolimus in kidney-pancreas and pancreas transplantation.
Transplantation proceedings 20081201
-
A combination of donor specific transfusion and rapamycin prolongs cardiac allograft survival in mice.
Transplantation proceedings 20081201
-
Treatment of chronic allograft nephropathy at late stages using everolimus or FTY720 in combination with cyclosporine.
Transplantation proceedings 20081201
-
Severe sirolimus-related inflammatory state anemia in an HIV+ liver transplant patient with calcineurin inhibitor renal insufficiency: a case report.
Transplantation proceedings 20081201
-
Fifteen years of clinical studies and clinical practice in renal transplantation: reviewing outcomes with de novo use of sirolimus in combination with cyclosporine.
Transplantation proceedings 20081201
-
Modern approaches to combining sirolimus with calcineurin inhibitors.
Transplantation proceedings 20081201
-
Reviewing the evidence for de novo immunosuppression with sirolimus.
Transplantation proceedings 20081201
-
Optimizing early de novo immunosuppression with sirolimus.
Transplantation proceedings 20081201
-
The impact of mTOR inhibitors on the development of malignancy.
Transplantation proceedings 20081201
-
Temsirolimus in renal cell carcinoma.
Transplantation proceedings 20081201
-
Minimizing the risk of posttransplant malignancy.
Transplantation proceedings 20081201
-
New approaches to de novo immunosuppression and steroid elimination.
Transplantation proceedings 20081201
-
Stratifying risk and targeting immunosuppressive strategies.
Transplantation proceedings 20081201
-
Treatment of saphenous vein graft lesions with paclitaxel- and sirolimus-eluting stents: comparison of short- and long-term clinical outcomes.
Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20081201
-
Rapamycin inhibits growth factor-induced cell cycle regulation in pancreatic beta cells.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20081201
-
[Outcome of patients implanted with bioabsorbable polymer sirolimus-eluting stent (Excel) and the durable polymer sirolimus-eluting stent (Cypher)].
Zhonghua xin xue guan bing za zhi 20081201
-
Comparison of vasa vasorum after intravascular stent placement with sirolimis drug-eluting and bare metal stents.
Journal of medical imaging and radiation oncology 20081201
-
Effects of rapamycin on intracellular cholesterol homeostasis of glomerular mesangial cell in the presence of interleukin-1 beta.
Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20081201
-
[Expression of mammalian target of rapamycin and p70 S6 kinase in rabbit periodontal tissues remodeling during orthodontic tooth movement].
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20081201
-
Temsirolimus: new drug. Metastatic kidney cancer: more assessment needed.
Prescrire international 20081201
-
Common corruption of the mTOR signaling network in human tumors.
Oncogene 20081201
-
Interference of drug-eluting stents with endothelium-dependent coronary vasomotion: evidence for device-specific responses.
Circulation. Cardiovascular interventions 20081201
-
Inhibition of apoptosis through localized delivery of rapamycin-loaded nanoparticles prevented neointimal hyperplasia and reendothelialized injured artery.
Circulation. Cardiovascular interventions 20081201
-
Regulation of androgen receptor transcriptional activity by rapamycin in prostate cancer cell proliferation and survival.
Oncogene 20081127
-
Sirolimus as primary immunosuppressant reduces left ventricular mass and improves diastolic function of the cardiac allograft.
Transplantation 20081127
-
Comparison of sirolimus plus tacrolimus versus sirolimus plus cyclosporine in high-risk renal allograft recipients: results from an open-label, randomized trial.
Transplantation 20081115
-
Susceptibility of human mesenchymal stem cells to tacrolimus, mycophenolic acid, and rapamycin.
Transplantation 20081115
-
Effects of immunosuppressive drugs on purified human B cells: evidence supporting the use of MMF and rapamycin.
Transplantation 20081115
-
Serial angiographic and intravascular ultrasound analysis of late stent strut fracture of sirolimus-eluting stents in native coronary arteries.
International journal of cardiology 20081112
-
Fracture of a sirolimus-eluting stent with migration.
International journal of cardiology 20081112
-
Thrombus causes fluctuations in arterial drug delivery from intravascular stents.
Journal of controlled release : official journal of the Controlled Release Society 20081112
-
Late stent recoil of the bioabsorbable everolimus-eluting coronary stent and its relationship with plaque morphology.
Journal of the American College of Cardiology 20081111
-
Long-term clinical benefit of sirolimus-eluting stents in patients with in-stent restenosis results of the RIBS-II (Restenosis Intra-stent: Balloon angioplasty vs. elective sirolimus-eluting Stenting) study.
Journal of the American College of Cardiology 20081111
-
A mathematical model for predicting drug release from a biodurable drug-eluting stent coating.
Journal of biomedical materials research. Part A 20081101
-
Tacrolimus withdrawal and conversion to sirolimus at three months post-pediatric renal transplantation.
Pediatric transplantation 20081101
-
Dopaminergic modulation of auditory cortex-dependent memory consolidation through mTOR.
Cerebral cortex (New York, N.Y. : 1991) 20081101
-
Cyclin B synthesis and rapamycin-sensitive regulation of protein synthesis during starfish oocyte meiotic divisions.
Molecular reproduction and development 20081101
-
[Primary chronic autoimmune neutropenia successfully treated with sirolimus].
La Revue de medecine interne 20081101
-
Reactive oxygen species in tumor necrosis factor-alpha-activated primary human keratinocytes: implications for psoriasis and inflammatory skin disease.
The Journal of investigative dermatology 20081101
-
mTOR mediates survival signals in malignant mesothelioma grown as tumor fragment spheroids.
American journal of respiratory cell and molecular biology 20081101
-
Conversion to sirolimus for chronic renal allograft dysfunction: risk factors for graft loss and severe side effects.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081101
-
Restoration of renal function in zebrafish models of ciliopathies.
Pediatric nephrology (Berlin, Germany) 20081101
-
Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism.
Amino acids 20081101
-
Dentritic cell derived IL-18 production is inhibited by rapamycin and sanglifehrin A, but not cyclosporine A.
Transplant immunology 20081101
-
Differential promotion of hematopoietic chimerism and inhibition of alloreactive T cell proliferation by combinations of anti-CD40Ligand, anti-LFA-1, everolimus, and deoxyspergualin.
Transplant immunology 20081101
-
Rapamycin reverses NPM-ALK-induced glucocorticoid resistance in lymphoid tumor cells by inhibiting mTOR signaling pathway, enhancing G1 cell cycle arrest and apoptosis.
Leukemia 20081101
-
[Molecular basis of targeted therapy in metastatic renal cancer].
Der Pathologe 20081101
-
Rapamycin does not improve insulin sensitivity despite elevated mammalian target of rapamycin complex 1 activity in muscles of ob/ob mice.
American journal of physiology. Regulatory, integrative and comparative physiology 20081101
-
Comparison of four different immunosuppression protocols without long-term steroid therapy in kidney recipients monitored by surveillance biopsy: five-year outcomes.
Transplant immunology 20081101
-
Sirolimus affects cardiomyocytes to reduce left ventricular mass in heart transplant recipients.
European heart journal 20081101
-
Sirolimus-based, calcineurin-inhibitor sparing immunotherapy, long-term (6-year) results.
Transplant immunology 20081101
-
Prolonged insulin independence after islet allotransplants in recipients with type 1 diabetes.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20081101
-
Pharmacokinetic interaction between everolimus and antifungal triazoles in a liver transplant patient.
The Annals of pharmacotherapy 20081101
-
Targeting the mammalian target of rapamycin in myxoid chondrosarcoma.
Anti-cancer drugs 20081101
-
Neointimal hyperplasia after sirolimus-eluting and paclitaxel-eluting stent implantation in diabetic patients: the Randomized Diabetes and Drug-Eluting Stent (DiabeDES) Intravascular Ultrasound Trial.
European heart journal 20081101
-
[Myocardial revascularization: the point in 2008].
Presse medicale (Paris, France : 1983) 20081101
-
Immediate and long-term results of treatment of complex lesions of the left anterior descending coronary artery involving a large diagonal branch with drug-eluting stents.
Journal of cardiovascular medicine (Hagerstown, Md.) 20081101
-
Switch of immunosuppression from cyclosporine A to everolimus: impact on pulse wave velocity in stable de-novo renal allograft recipients.
Journal of hypertension 20081101
-
Mechanism of action of rapalogues: the antiangiogenic hypothesis.
Expert opinion on investigational drugs 20081101
-
Drug-eluting stents for the treatment of ostial coronary lesions: comparison of sirolimus-eluting stent with paclitaxel-eluting stent.
Coronary artery disease 20081101
-
Minimization of immunosuppression: transplant immunology.
Transplant immunology 20081101
-
Sirolimus treatment of left ventricular hypertrophy: who, and when?
European heart journal 20081101
-
Comparison of sirolimus-eluting stent and paclitaxel-eluting stent for long-term cardiac adverse events in diabetic patients: the Korean Multicenter Angioplasty Team (KOMATE) Registry.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081101
-
Clinical presentation of patients with late target lesion revascularization.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081101
-
Growth stimulation leads to cellular senescence when the cell cycle is blocked.
Cell cycle (Georgetown, Tex.) 20081101
-
A randomized comparison of sirolimus-eluting versus bare metal stents in the treatment of diabetic patients with native coronary artery lesions: the DECODE study.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081101
-
Regression of pulmonary lymphangioleiomyomatosis (PLAM)-associated retroperitoneal angiomyolipoma post-lung transplantation with rapamycin treatment.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20081101
-
Gingival status of Brazilian renal transplant recipients under sirolimus-based regimens.
Journal of periodontology 20081101
-
Intractable Prinzmetal's angina three months after implantation of sirolimus-eluting stent.
The Journal of invasive cardiology 20081101
-
Systemic immunosuppressive therapy with oral Sirolimus after bare metal stent implantation: the missing alternative in the prevention of coronary restenosis after percutaneous coronary interventions.
Recent patents on cardiovascular drug discovery 20081101
-
Systemic therapy for metastatic renal cell carcinoma.
The Urologic clinics of North America 20081101
-
[Treatment of drug-eluting stent restenosis with another drug-eluting stent: do not fail the second time!].
Revista espanola de cardiologia 20081101
-
[Treatment of Paclitaxel-eluting stent restenosis with sirolimus-eluting stent implantation: angiographic and clinical outcomes].
Revista espanola de cardiologia 20081101
-
[67-year-old patient with speech disorder and dysphagia].
Deutsche medizinische Wochenschrift (1946) 20081101
-
Tolerance profile of the proliferation signal inhibitors everolimus and sirolimus in heart transplantation.
Transplantation proceedings 20081101
-
Preliminary experience with conversion from calcineurin inhibitors to everolimus in cardiac transplantation maintenance therapy.
Transplantation proceedings 20081101
-
Conversion to rapamycin in a renal transplant patient with von Hippel-Lindau disease: encouraging results-a case report.
Transplantation proceedings 20081101
-
Use of everolimus in de novo renal recipients: initial experience in the Greek population.
Transplantation proceedings 20081101
-
Metabolic changes following conversion from an anticalcineurin-based therapy to an everolimus-based one: a single-center experience.
Transplantation proceedings 20081101
-
Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration.
Cell metabolism 20081101
-
[Oral ulcers in kidney allograft recipients treated with sirolimus].
Annales de dermatologie et de venereologie 20081101
-
Percutaneous coronary implantation of sirolimus-eluting stents in unselected patients and lesions: clinical results and multiple outcome predictors.
American heart journal 20081101
-
Long-term coronary endothelial function after zotarolimus-eluting stent implantation. A 9 month comparison between zotarolimus-eluting and sirolimus-eluting stents.
International heart journal 20081101
-
Four-year safety and efficacy of the unrestricted use of sirolimus- and paclitaxel-eluting stents in coronary artery bypass grafts.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20081101
-
Very late thrombosis in acute myocardial infarction: drug-eluting versus uncoated stents.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20081101
-
Long-term safety and efficacy are observed after implantation of Zotarolimus-Eluting stent in real-world clinical practice.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20081101
-
[Benefit-risk ratio of coronary drug-eluting stents: 2nd part: evaluation in the diabetic population].
Revue medicale de Liege 20081101
-
The changing face of angiographic patterns of restenosis after drug-eluting stent placement: sirolimus versus paclitaxel-eluting stent.
International journal of cardiology 20081030
-
Simultaneous subacute stent thrombosis of two sirolimus-eluting stents in a patient treated by ReoPro, thrombus aspiration and triple anti-platelet agents.
International journal of cardiology 20081030
-
Rapamycin downregulates the inhibitory receptors ILT2, ILT3, ILT4 on human dendritic cells and yet induces T cell hyporesponsiveness independent of FoxP3 induction.
Immunology letters 20081030
-
One year follow-up of steroid-free immunosuppression plus everolimus in isolated pancreas transplantation.
Transplantation 20081027
-
mTORC1 inhibitors: is temsirolimus in renal cancer telling us how they really work?
British journal of cancer 20081021
-
[Effects of constant magnetic fields on proliferation and migration of endothelial progenitor cells under rapamycin intervention: experiment with rats].
Zhonghua yi xue za zhi 20081021
-
[Sirolimus inhibits the expression of type I collagen and fibronectin in cultured renal cortical myofibroblasts].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20081018
-
Metabolic stress induces the lysosomal degradation of neuropilin-1 but not neuropilin-2.
The Journal of biological chemistry 20081017
-
Melatonin prevents ischemic brain injury through activation of the mTOR/p70S6 kinase signaling pathway.
Neuroscience letters 20081017
-
The TSC-mTOR signaling pathway regulates the innate inflammatory response.
Immunity 20081017
-
Dual inhibition of PI3Kalpha and mTOR as an alternative treatment for Kaposi's sarcoma.
Cancer research 20081015
-
Shp2 negatively regulates growth in cardiomyocytes by controlling focal adhesion kinase/Src and mTOR pathways.
Circulation research 20081010
-
Very late stent fracture associated with a sirolimus-eluting stent.
Heart, lung & circulation 20081001
-
An investigation of adhesion in drug-eluting stent layers.
Journal of biomedical materials research. Part A 20081001
-
Lack of antileukemic activity of rapamycin in elderly patients with acute myeloid leukemia evolving from a myelodysplastic syndrome.
Leukemia research 20081001
-
Sirolimus reduces the incidence and progression of UVB-induced skin cancer in SKH mice even with co-administration of cyclosporine A.
The Journal of investigative dermatology 20081001
-
Different renal toxicity profiles in the association of cyclosporine and tacrolimus with sirolimus in rats.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081001
-
Thrombin induces osteoprotegerin synthesis via phosphatidylinositol 3'-kinase/mammalian target of rapamycin pathway in human periodontal ligament cells.
Journal of periodontal research 20081001
-
[Value of targeted therapy for prostate cancer].
Der Urologe. Ausg. A 20081001
-
[Value of targeted therapies for renal cell cancer].
Der Urologe. Ausg. A 20081001
-
Effects of peroxisome proliferator-activated receptor alpha (PPARalpha) agonists on leucine-induced phosphorylation of translational targets in C2C12 cells.
Biochimica et biophysica acta 20081001
-
Mechanisms of Disease: survival benefit of temsirolimus validates a role for mTOR in the management of advanced RCC.
Nature clinical practice. Oncology 20081001
-
Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1.
Human molecular genetics 20081001
-
Phospho-proteomic approach to identify new targets of leucine deprivation in muscle cells.
Analytical biochemistry 20081001
-
Simultaneous islet and kidney transplantation in seven patients with type 1 diabetes and end-stage renal disease using a glucocorticoid-free immunosuppressive regimen with alemtuzumab induction.
Diabetes 20081001
-
Randomized comparison of early inflammatory response after sirolimus-eluting stent vs bare metal stent implantation in native coronary lesions.
Clinica chimica acta; international journal of clinical chemistry 20081001
-
Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancement.
Neurobiology of disease 20081001
-
Prolonged response to temsirolimus in a pre-treated patient with metastatic renal cell carcinoma and poor performance status.
Clinical oncology (Royal College of Radiologists (Great Britain)) 20081001
-
Kaposi sarcoma in transplantation.
Transplantation reviews (Orlando, Fla.) 20081001
-
Effect of mTOR inhibitor on body weight: from an experimental rat model to human transplant patients.
Transplant international : official journal of the European Society for Organ Transplantation 20081001
-
Severe everolimus-associated pneumonitis in a renal transplant recipient.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081001
-
Bioabsorbable drug-eluting stents: the future of coronary angioplasty?
Nature clinical practice. Cardiovascular medicine 20081001
-
Leucine stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing mTORC1 activation.
American journal of physiology. Endocrinology and metabolism 20081001
-
[Targeted therapy - point blank or single shot].
Der Urologe. Ausg. A 20081001
-
Prolongation of corneal allograft survival by topical application of everolimus in experimental keratoplasty.
Ophthalmic research 20081001
-
Everolimus- and zotarolimus-eluting stents for bare metal stent in-stent restenosis treatment: a prospective study.
Journal of interventional cardiology 20081001
-
Morphological and biochemical characterization of basal and starvation-induced autophagy in isolated adult rat cardiomyocytes.
American journal of physiology. Heart and circulatory physiology 20081001
-
Impact of current transplantation management on the development of cytomegalovirus disease after renal transplantation.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20081001
-
TOR regulates the subcellular distribution of DIM2, a KH domain protein required for cotranscriptional ribosome assembly and pre-40S ribosome export.
RNA (New York, N.Y.) 20081001
-
Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway.
Nature immunology 20081001
-
Prevention of cancer by inhibiting aging.
Cancer biology & therapy 20081001
-
Persistent clinical impact of cytomegalovirus in organ transplantation.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20081001
-
Sirolimus: a potential chemopreventive agent.
The Journal of investigative dermatology 20081001
-
Insulin induces monocytic CXCL8 secretion by the mitogenic signalling pathway.
Cytokine 20081001
-
Impact of mammalian target of rapamycin inhibition on lymphoid homing and tolerogenic function of nanoparticle-labeled dendritic cells following allogeneic hematopoietic cell transplantation.
Journal of immunology (Baltimore, Md. : 1950) 20081001
-
Suboptimal percutaneous coronary intervention.
The American journal of cardiology 20081001
-
Prognostic value of lesion classification for the clinical outcome after stent placement.
The American journal of cardiology 20081001
-
Novel drugs for renal cell carcinoma.
Expert opinion on investigational drugs 20081001
-
Complete versus incomplete revascularization in patients with multivessel disease undergoing percutaneous coronary intervention with drug-eluting stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081001
-
Sirolimus-eluting stents versus bare-metal stents in patients with in-stent restenosis: results of a pooled analysis of two randomized studies.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081001
-
Letter by Kounis et al regarding article, 'sirolimus-eluting stents suppress neointimal formation irrespective of metallic allergy'.
Circulation journal : official journal of the Japanese Circulation Society 20081001
-
'Neither horseshoes nor hand grenades'--does close count in percutaneous coronary revascularization?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081001
-
Repetita iuvant.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081001
-
[Systemic therapy of metastasizing renal cell carcinoma].
Der Urologe. Ausg. A 20081001
-
Recent advances in the treatment of renal cell carcinoma and the role of targeted therapies.
European journal of cancer (Oxford, England : 1990) 20081001
-
Unprotected left main coronary artery bifurcation stenosis: impact of plaque debulking prior to single sirolimus-eluting stent implantation.
The Journal of invasive cardiology 20081001
-
[Recent therapeutic progress in non-Hodgkin lymphoma: focusing on diffuse large B-cell lymphoma and follicular lymphoma].
[Rinsho ketsueki] The Japanese journal of clinical hematology 20081001
-
Targeted therapies for metastatic renal cell carcinoma: an overview of toxicity and dosing strategies.
The oncologist 20081001
-
Robust and systematic drug screening method using chemical arrays and the protein library: identification of novel inhibitors of carbonic anhydrase II.
Bioscience, biotechnology, and biochemistry 20081001
-
ABT-263 and rapamycin act cooperatively to kill lymphoma cells in vitro and in vivo.
Molecular cancer therapeutics 20081001
-
Size matters (but so does time), and it's OK to be different.
Developmental cell 20081001
-
The TOR pathway couples nutrition and developmental timing in Drosophila.
Developmental cell 20081001
-
Systemic exposure of everolimus after stent implantation: a pharmacokinetic study.
American heart journal 20081001
-
Avoidance of calcineurin inhibitors with use of proliferation signal inhibitors in de novo heart transplantation with renal failure.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20081001
-
Heart transplantation under cyclosporine or tacrolimus combined with mycophenolate mofetil or everolimus.
Transplantation proceedings 20081001
-
Rapamycin-induced cytotoxic signal transduction pathway.
Transplantation proceedings 20081001
-
Rapamycin and cyclosporine have different effects on expression of Ang-1 and Ang-2 and Tie2 in rat renal allograft with chronic allograft nephropathy.
Transplantation proceedings 20081001
-
Sirolimus-eluting and paclitaxel-eluting stents for the treatment of coronary bifurcations.
American heart journal 20081001
-
Regression of subependymal giant cell astrocytoma with rapamycin in tuberous sclerosis complex.
Journal of child neurology 20081001
-
[Effect of chemotherapy with cisplatin and rapamycin against Hep-2 cells in vitro].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20081001
-
Combination treatment with plasmapheresis and sirolimus does not seem to benefit nephrogenic systemic fibrosis.
The International journal of artificial organs 20081001
-
mTOR inhibition reverses acquired endocrine therapy resistance of breast cancer cells at the cell proliferation and gene-expression levels.
Cancer science 20081001
-
Status of drug-eluting coronary stents.
Medicine and health, Rhode Island 20081001
-
Out with the old, in with the new: immunosuppression minimization in children.
Current opinion in organ transplantation 20081001
-
Therapies for interstitial lung disease: past, present and future.
Therapeutic advances in respiratory disease 20081001
-
[Blockage of mTOR signaling pathway by rapamycin contributes to inhibition of tumor cell proliferation in ALK-positive lymphoid cell strains].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20081001
-
A randomized, controlled, multicenter trial to evaluate the safety and efficacy of zotarolimus- versus paclitaxel-eluting stents in de novo occlusive lesions in coronary arteries The ZoMaxx I trial.
JACC. Cardiovascular interventions 20081001
-
The process of bringing new drug-eluting stents to market will they see the light of day?
JACC. Cardiovascular interventions 20081001
-
Differential healing responses in polymer- and nonpolymer-based sirolimus-eluting stents.
JACC. Cardiovascular interventions 20081001
-
Preliminary results of the hydroxyapatite nonpolymer-based sirolimus-eluting stent for the treatment of single de novo coronary lesions a first-in-human analysis of a third-generation drug-eluting stent system.
JACC. Cardiovascular interventions 20081001
-
Tissue sirolimus levels of distal vessel, stented myocardium, and distal myocardium.
JACC. Cardiovascular interventions 20081001
-
Primary percutaneous coronary intervention with drug-eluting stents: another chapter in the stent controversy.
Circulation. Cardiovascular interventions 20081001
-
Primary percutaneous coronary intervention for acute myocardial infarction: long-term outcome after bare metal and drug-eluting stent implantation.
Circulation. Cardiovascular interventions 20081001
-
Incidence and correlates of drug-eluting stent thrombosis in routine clinical practice. 4-year results from a large 2-institutional cohort study.
Journal of the American College of Cardiology 20080930
-
Biolimus-eluting stent with biodegradable polymer versus sirolimus-eluting stent with durable polymer for coronary revascularisation (LEADERS): a randomised non-inferiority trial.
Lancet (London, England) 20080927
-
Drug-eluting stents: is new necessarily better?
Lancet (London, England) 20080927
-
Calcineurin inhibitor sparing in renal transplantation.
Transplantation 20080927
-
The anchor-away technique: rapid, conditional establishment of yeast mutant phenotypes.
Molecular cell 20080926
-
Angioscopic findings of delayed healing at sites of sirolimus-eluting stent overlap after 21-month implantation.
International journal of cardiology 20080916
-
Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation.
Blood 20080915
-
Defects in skin gamma delta T cell function contribute to delayed wound repair in rapamycin-treated mice.
Journal of immunology (Baltimore, Md. : 1950) 20080915
-
Safety of drug-eluting stents in patients with left ventricular dysfunction undergoing percutaneous coronary intervention.
The American journal of cardiology 20080915
-
Enhancing mammalian target of rapamycin (mTOR)-targeted cancer therapy by preventing mTOR/raptor inhibition-initiated, mTOR/rictor-independent Akt activation.
Cancer research 20080915
-
FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression.
Science (New York, N.Y.) 20080912
-
Efficacy of RAD001 (everolimus) and octreotide LAR in advanced low- to intermediate-grade neuroendocrine tumors: results of a phase II study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080910
-
Rapamycin down-regulates LDL-receptor expression independently of SREBP-2.
Biochemical and biophysical research communications 20080905
-
CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation.
The Journal of biological chemistry 20080905
-
Long-term efficacy and safety of Chinese made sirolimus eluting stents: results, including off label usage, from two centres over three years.
Chinese medical journal 20080905
-
Inhibition of mTOR restores cisplatin sensitivity through down-regulation of growth and anti-apoptotic proteins.
European journal of pharmacology 20080904
-
Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer.
European journal of pharmacology 20080904
-
Rapamycin reduces VEGF expression in retinal pigment epithelium (RPE) and inhibits RPE-induced sprouting angiogenesis in vitro.
FEBS letters 20080903
-
Major treatment improvements encourage kidney cancer researchers to seek further gains.
Journal of the National Cancer Institute 20080903
-
SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth.
Cell metabolism 20080903
-
Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer.
The Journal of clinical investigation 20080902
-
The impact of lesion length and vessel size on outcomes after sirolimus-eluting stent implantation for in-stent restenosis.
Heart (British Cardiac Society) 20080901
-
Introducing the first polymer-free leflunomide eluting stent.
Atherosclerosis 20080901
-
Combination antifungal therapy involving amphotericin B, rapamycin and 5-fluorocytosine using PEG-phospholipid micelles.
Pharmaceutical research 20080901
-
Rapamycin attenuates the severity of established nephritis in lupus-prone NZB/W F1 mice.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080901
-
Use of sirolimus in IPEX and IPEX-like children.
Journal of clinical immunology 20080901
-
Kaposi's sarcoma and mTOR: a crossroad between viral infection neoangiogenesis and immunosuppression.
Transplant international : official journal of the European Society for Organ Transplantation 20080901
-
The alpha4-containing form of protein phosphatase 2A in liver and hepatic cells.
Journal of cellular biochemistry 20080901
-
Rapamycin monotherapy in patients with type 1 diabetes modifies CD4+CD25+FOXP3+ regulatory T-cells.
Diabetes 20080901
-
Maternal protein restriction during early lactation induces GLUT4 translocation and mTOR/Akt activation in adipocytes of adult rats.
American journal of physiology. Endocrinology and metabolism 20080901
-
Lifetime cost-effectiveness of calcineurin inhibitor withdrawal after de novo renal transplantation.
Journal of the American Society of Nephrology : JASN 20080901
-
Late and very late stent thrombosis following drug-eluting stent implantation in unprotected left main coronary artery: a multicentre registry.
European heart journal 20080901
-
Autophagy-inducing agents augment the antitumor effect of telerase-selve oncolytic adenovirus OBP-405 on glioblastoma cells.
Gene therapy 20080901
-
Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin.
Molecular and cellular neurosciences 20080901
-
Huntington's disease: degradation of mutant huntingtin by autophagy.
The FEBS journal 20080901
-
A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression.
American journal of physiology. Cell physiology 20080901
-
Late drug-eluting stent thrombosis in unprotected left main coronary artery lesions--sometimes possible, but rarely definite or probable.
European heart journal 20080901
-
Targeted therapy in renal cell carcinoma.
Current opinion in urology 20080901
-
Positive reasons for publishing negative findings.
The American journal of gastroenterology 20080901
-
A multicenter, randomized, double-blind trial of everolimus versus azathioprine and placebo to maintain steroid-induced remission in patients with moderate-to-severe active Crohn's disease.
The American journal of gastroenterology 20080901
-
Strut fracture: a further concern with drug-eluting stents.
Journal of cardiovascular medicine (Hagerstown, Md.) 20080901
-
Small molecule enhancers of autophagy for neurodegenerative diseases.
Molecular bioSystems 20080901
-
Everolimus (RAD001) and anti-angiogenic cyclophosphamide show long-term control of gastric cancer growth in vivo.
Cancer biology & therapy 20080901
-
Sirolimus-induced aphthous ulcers which disappeared with conversion to everolimus.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20080901
-
Use of sirolimus (rapamycin) to treat refractory Crohn's disease.
Gut 20080901
-
Ras-mediated up-regulation of survivin expression in cytokine-dependent murine pro-B lymphocytic cells.
The Tohoku journal of experimental medicine 20080901
-
One-year clinical outcomes of dialysis patients after implantation with sirolimus-eluting coronary stents.
Circulation journal : official journal of the Japanese Circulation Society 20080901
-
Urothelial carcinoma in kidney transplant recipients: conversion from calcineurin inhibitor to proliferation signal inhibitor?
American journal of kidney diseases : the official journal of the National Kidney Foundation 20080901
-
Involvement of insulin in early development of mouse one-cell stage embryos.
Science in China. Series C, Life sciences 20080901
-
Pharmacodynamic-guided modified continuous reassessment method-based, dose-finding study of rapamycin in adult patients with solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080901
-
Chemoprevention and treatment of experimental Cowden's disease by mTOR inhibition with rapamycin.
Cancer research 20080901
-
Safety of drug-coated stents.
Expert opinion on drug safety 20080901
-
Late unilateral pulmonary edema in single lung transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080901
-
mTOR inhibitors and unilateral edema.
Revista espanola de cardiologia 20080901
-
Novel therapeutic options in metastatic renal cancer - review and post ASCO 2007 update.
Reviews on recent clinical trials 20080901
-
Symptomatic pulmonary allograft Kaposi's sarcoma in two lung transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080901
-
Impact of variability of sirolimus trough level on chronic allograft nephropathy.
Transplantation proceedings 20080901
-
De novo sirolimus-based regimen in Thai renal transplant recipients.
Transplantation proceedings 20080901
-
Sirolimus conversion experience in a single center.
Transplantation proceedings 20080901
-
Everolimus with reduced-dose cyclosporine in de novo renal transplant recipients: Philippine experience.
Transplantation proceedings 20080901
-
Possible mechanism by which rapamycin increases cyclosporine nephrotoxicity.
Transplantation proceedings 20080901
-
Sirolimus does not absolutely abolish the occurrence/recurrence of urothelial carcinoma in renal transplant recipients.
Transplantation proceedings 20080901
-
Late spontaneous kidney graft decapsulation after administration of sirolimus in a recipient with chronic hepatitis B and C infection: a case report.
Transplantation proceedings 20080901
-
Sirolimus used during pregnancy in a living related renal transplant recipient: a case report.
Transplantation proceedings 20080901
-
Long-term efficacy and safety of sirolimus-eluting vs bare-metal stents.
Connecticut medicine 20080901
-
[Renal cell carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy 20080901
-
Pilot study of rapamycin in patients with hormone-refractory prostate cancer.
Clinical genitourinary cancer 20080901
-
NCCN Task Force Report: mTOR inhibition in solid tumors.
Journal of the National Comprehensive Cancer Network : JNCCN 20080901
-
Clinical investigations in T-cell and NK-cell non-Hodgkin lymphoma.
Clinical advances in hematology & oncology : H&O 20080901
-
Use of sirolimus in a case of severe paraquat poisoning.
Clinical toxicology (Philadelphia, Pa.) 20080901
-
Complete fracture and restenosis of sirolimus-eluting stent in ostial saphenous vein graft.
International journal of cardiology 20080829
-
Drug eluting stents in patients with diabetes.
BMJ (Clinical research ed.) 20080829
-
Rapamycin inhibits F-actin reorganization and phosphorylation of focal adhesion proteins.
Oncogene 20080828
-
Reduction in erythropoietin resistance after conversion from sirolimus to enteric coated mycophenolate sodium.
Transplantation 20080827
-
Improved renal function, with similar proteinuria, after two years of early tacrolimus withdrawal from a regimen of sirolimus plus tacrolimus.
Transplantation 20080827
-
A randomized comparison of sirolimus- versus Paclitaxel-eluting stent implantation in patients with diabetes mellitus.
Journal of the American College of Cardiology 20080826
-
Angioscopic comparison of neointimal coverage between zotarolimus- and sirolimus-eluting stents.
Journal of the American College of Cardiology 20080826
-
Heterogeneous nuclear ribonucleoprotein A1 regulates cyclin D1 and c-myc internal ribosome entry site function through Akt signaling.
The Journal of biological chemistry 20080822
-
Firebird and cypher sirolimus-eluting stents and bare metal stents in treatment of very long coronary lesions.
Chinese medical journal 20080820
-
Quantitation of autophagy by luciferase release assay.
Autophagy 20080816
-
Frequency modulation of synchronized Ca(2+) spikes in cultured hippocampal networks through mTOR.
Neuroscience letters 20080815
-
Effect of rapamycin alone and in combination with sorafenib in an orthotopic model of human hepatocellular carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20080815
-
Prolongation of cardiac allograft survival by rapamycin and the invariant natural killer T cell glycolipid agonist OCH.
Transplantation 20080815
-
S6K1 plays a key role in glial transformation.
Cancer research 20080815
-
Tumorigenic activity and therapeutic inhibition of Rheb GTPase.
Genes & development 20080815
-
Watchdog set to reject four drugs for kidney cancer on the NHS.
BMJ (Clinical research ed.) 20080814
-
Progression-free survival as endpoint in metastatic RCC?
Lancet (London, England) 20080809
-
Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial.
Lancet (London, England) 20080809
-
A strategy to offset the extra cost of sirolimus-eluting stent in patients undergoing intervention for acute myocardial infarction.
International journal of cardiology 20080801
-
Activation of the mTOR signaling pathway in breast cancer and its correlation with the clinicopathologic variables.
Breast cancer research and treatment 20080801
-
Everolimus in patients with rheumatoid arthritis receiving concomitant methotrexate: a 3-month, double-blind, randomised, placebo-controlled, parallel-group, proof-of-concept study.
Annals of the rheumatic diseases 20080801
-
Sirolimus and regression of Kaposi's sarcoma in immunosuppressed transplant patient.
Journal of the European Academy of Dermatology and Venereology : JEADV 20080801
-
Antineoplastic effect of rapamycin is potentiated by inhibition of IRS-1 signaling in prostate cancer cells xenografts.
Journal of cancer research and clinical oncology 20080801
-
Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells.
The Journal of investigative dermatology 20080801
-
The PI 3-kinase and mTOR signaling pathways are important modulators of epithelial tubule formation.
Journal of cellular physiology 20080801
-
Temsirolimus safety profile and management of toxic effects in patients with advanced renal cell carcinoma and poor prognostic features.
Annals of oncology : official journal of the European Society for Medical Oncology 20080801
-
Hypoxia-inducible factor-2alpha: effect on radiation sensitivity and differential regulation by an mTOR inhibitor.
BJU international 20080801
-
The macrolide everolimus forms an unusual metabolite in animals and humans: identification of a phosphocholine ester.
Drug metabolism and disposition: the biological fate of chemicals 20080801
-
mTOR in squamous cell carcinoma of the oesophagus: a potential target for molecular therapy?
Journal of clinical pathology 20080801
-
Differential effects of rapamycin in anti-GBM glomerulonephritis.
Journal of the American Society of Nephrology : JASN 20080801
-
Stimulation of autophagy suppresses the intracellular survival of Burkholderia pseudomallei in mammalian cell lines.
Autophagy 20080801
-
What controls TOR?
IUBMB life 20080801
-
Localization of autophagy-related proteins in yeast using a versatile plasmid-based resource of fluorescent protein fusions.
Autophagy 20080801
-
Temsirolimus in metastatic renal cell carcinoma.
Annals of oncology : official journal of the European Society for Medical Oncology 20080801
-
mTOR inhibitor monotherapy is insufficient to suppress viremia and disease progression in Epstein-Barr virus-driven lymphoproliferative disorders (EBV-LPD).
American journal of hematology 20080801
-
Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma: a phase 2 trial in the North Central Cancer Treatment Group.
Cancer 20080801
-
The mTOR inhibitor rapamycin significantly improves facial angiofibroma lesions in a patient with tuberous sclerosis.
The British journal of dermatology 20080801
-
Randomized trial of three rapamycin-eluting stents with different coating strategies for the reduction of coronary restenosis.
European heart journal 20080801
-
The potential clinical utility of intravascular ultrasound guidance in patients undergoing percutaneous coronary intervention with drug-eluting stents.
European heart journal 20080801
-
The effect of rapamycin on DNA synthesis in multiple tissues from late gestation fetal and postnatal rats.
American journal of physiology. Cell physiology 20080801
-
Vascular endothelial growth factor protein levels and gene expression in peripheral monocytes after stenting: a randomized comparative study of sirolimus-eluting and bare-metal stents.
European heart journal 20080801
-
Patient selection critical for calcineurin inhibitor withdrawal in pediatric kidney transplantation.
Pediatric transplantation 20080801
-
Hepatic translation control in the late-gestation fetal rat.
American journal of physiology. Regulatory, integrative and comparative physiology 20080801
-
Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis.
Nature medicine 20080801
-
Effect of sirolimus on left ventricular hypertrophy in kidney transplant recipients: a 1-year nonrandomized controlled trial.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20080801
-
Biodegradable coating for drug-eluting stents--more than a facelift?
European heart journal 20080801
-
Combination of rapamycin and 17-allylamino-17-demethoxygeldanamycin abrogates Akt activation and potentiates mTOR blockade in breast cancer cells.
Anti-cancer drugs 20080801
-
In-vitro synergism of m-TOR inhibitors, statins, and classical chemotherapy: potential implications in acute leukemia.
Anti-cancer drugs 20080801
-
Sirolimus-eluting stent implantation for bare-metal in-stent restenosis: is there any evidence for a late catch-up phenomenon?
Journal of cardiovascular medicine (Hagerstown, Md.) 20080801
-
Clinical-grade preparation of human natural regulatory T-cells encoding the thymidine kinase suicide gene as a safety gene.
The journal of gene medicine 20080801
-
The MAP kinase-activated protein kinase Rck2p plays a role in rapamycin sensitivity in Saccharomyces cerevisiae and Candida albicans.
FEMS yeast research 20080801
-
Nutrient content of diet affects the signaling activity of the insulin/target of rapamycin/p70 S6 kinase pathway in the African malaria mosquito Anopheles gambiae.
Journal of insect physiology 20080801
-
Two-year outcome of patients treated with sirolimus- versus paclitaxel-eluting stents in an unselected population with coronary artery disease (from the REWARDS Registry).
The American journal of cardiology 20080801
-
Intravascular ultrasound evaluation of optimal drug-eluting stent expansion after poststent balloon dilation using a noncompliant balloon versus a semicompliant balloon (from the Poststent Optimal Stent Expansion Trial [POET]).
The American journal of cardiology 20080801
-
Angiographic patterns of drug-eluting stent restenosis and one-year outcomes after treatment with repeated percutaneous coronary intervention.
The American journal of cardiology 20080801
-
Sirolimus, tacrolimus, and low-dose methotrexate as graft-versus-host disease prophylaxis in related and unrelated donor reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080801
-
Sirolimus in combination with tacrolimus in allogeneic stem cell transplantation--timing and conditioning regimen may be crucial.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080801
-
Development of a predictive limited sampling strategy for estimation of mycophenolic acid area under the concentration time curve in patients receiving concomitant sirolimus or cyclosporine.
Therapeutic drug monitoring 20080801
-
Biodegradable polymers--are they the answer to late stent thrombosis? Too early to tell.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080801
-
Novel bioabsorbable salicylate-based polymer as a drug-eluting stent coating.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080801
-
Early days of an ingenious aspirin and sirolimus-eluting stent.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080801
-
Long-term clinical, angiographic, and intravascular ultrasound outcomes of biodegradable polymer-coated sirolimus-eluting stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080801
-
Optical coherence tomography: high resolution intravascular imaging to evaluate vascular healing after coronary stenting.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080801
-
Sirolimus amelioration of clinical symptoms of recurrent lymphangioleiomyomatosis after living-donor lobar lung transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080801
-
Evaluation of a deuterium-labeled internal standard for the measurement of sirolimus by high-throughput HPLC electrospray ionization tandem mass spectrometry.
Clinical chemistry 20080801
-
Corneal permeation studies of everolimus microemulsion.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20080801
-
A small molecule-directed approach to control protein localization and function.
Yeast (Chichester, England) 20080801
-
Evaluation of the mammalian target of rapamycin pathway and the effect of rapamycin on target expression and cellular proliferation in osteosarcoma cells from dogs.
American journal of veterinary research 20080801
-
Temsirolimus, an mTOR inhibitor for treatment of patients with advanced renal cell carcinoma.
Clinical journal of oncology nursing 20080801
-
Two-year intravascular ultrasound observations in diabetic patients treated with single and double dose sirolimus-eluting stents: results of the double dose diabetes (3D) study.
The Journal of invasive cardiology 20080801
-
Coexistent in-stent restenosis, late incomplete stent apposition and mural thrombus in a zotarolimus-eluting stent.
The Journal of invasive cardiology 20080801
-
'Black hole' restenosis after sirolimus-eluting stent implantation.
The Journal of invasive cardiology 20080801
-
Oral sirolimus for prevention of recurrent infrainguinal arterial obstructions after surgical and endovascular revascularizations.
VASA. Zeitschrift fur Gefasskrankheiten 20080801
-
Rapamycin modulates the maturation of rat bone marrow-derived dendritic cells.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20080801
-
[Can defective TGF-Beta signaling be an Achilles heel in human cancer?].
Ai zheng = Aizheng = Chinese journal of cancer 20080801
-
In-stent restenosis in bare metal stents versus sirolimus-eluting stents after primary coronary intervention for acute myocardial infarction and subsequent transcoronary transplantation of autologous stem cells.
Clinical cardiology 20080801
-
Aging, stem cells, and mammalian target of rapamycin: a prospect of pharmacologic rejuvenation of aging stem cells.
Rejuvenation research 20080801
-
Cotylenin A, a new differentiation inducer, and rapamycin cooperatively inhibit growth of cancer cells through induction of cyclin G2.
Cancer science 20080801
-
Inference of protein complex activities from chemical-genetic profile and its applications: predicting drug-target pathways.
PLoS computational biology 20080801
-
What the similarities of specific polycystic liver and kidney diseases can teach us about both.
Nephrology news & issues 20080801
-
Conversion from sirolimus to everolimus in maintenance renal transplant recipients within a calcineurin inhibitor-free regimen: results of a 6-month pilot study.
Clinical nephrology 20080801
-
[Effect of rapamycin in inducing naïve murine effector T cell convert to regulatory T cell].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20080801
-
[Rapamycin-loaded poly (lactic-co-glycolic) acid nanoparticles for intraarterial local drug delivery: preparation, characterization, and in vitro/in vivo release].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20080801
-
Clinical outcomes of sirolimus with eluting stent implantation in coronary artery disease.
JPMA. The Journal of the Pakistan Medical Association 20080801
-
One year results of a new in situ length-adjustable stent platform with a biodegradable biolimus A9 eluting polymer: results of the CUSTOM-II trial.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080801
-
Safety in simple versus complex stenting of coronary artery bifurcation lesions. The nordic bifurcation study 14-month follow-up results.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080801
-
Elective implantation of sirolimus-eluting stents for bifurcated and non-bifurcated unprotected left main coronary artery lesions: clinical outcomes at one year.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080801
-
3-year follow-up of the SISR (Sirolimus-Eluting Stents Versus Vascular Brachytherapy for In-Stent Restenosis) trial.
JACC. Cardiovascular interventions 20080801
-
Lack of association between large angiographic late loss and low risk of in-stent thrombus: angioscopic comparison between paclitaxel- and sirolimus-eluting stents.
Circulation. Cardiovascular interventions 20080801
-
Antidepressive-like effects of rapamycin in animal models: Implications for mTOR inhibition as a new target for treatment of affective disorders.
Brain research bulletin 20080730
-
Endothelial cell recovery between comparator polymer-based drug-eluting stents.
Journal of the American College of Cardiology 20080729
-
Beneficial effect of omega-3 fatty acids on sirolimus- or everolimus-induced hypertriglyceridemia in heart transplant recipients.
Transplantation 20080727
-
Clinical trials probe new therapies for some difficult-to-treat cancers.
JAMA 20080723
-
Anti-proinflammatory effects of sirolimus on human islet preparations.
Transplantation 20080715
-
Chronic kidney disease--a common and serious complication after intestinal transplantation.
Transplantation 20080715
-
Prolongation of cardiac and islet allograft survival by a blocking hamster anti-mouse CXCR3 monoclonal antibody.
Transplantation 20080715
-
Sirolimus (rapamycin) induced proteinuria in a patient undergoing allogeneic hematopoietic stem cell transplant.
Transplantation 20080715
-
Sirolimus in metatastic renal cell carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080710
-
[Effects of sirolimus-eluting stent and the paclitaxel-eluting stent: a three-year follow-up study].
Zhonghua yi xue za zhi 20080708
-
Simultaneous subacute stent thrombosis after implantation of sirolimus-eluting stent and bare-metal stent.
International journal of cardiology 20080704
-
Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors.
Oncogene 20080703
-
Localization of polypyrimidine-tract-binding protein is involved in the regulation of albumin synthesis by branched-chain amino acids in HepG2 cells.
The Journal of nutritional biochemistry 20080701
-
Antiproliferative effects of rapamycin as a single agent and in combination with carboplatin and paclitaxel in head and neck cancer cell lines.
Cancer chemotherapy and pharmacology 20080701
-
Sirolimus enhances the effect of apoptotic cell infusion on hematopoietic engraftment and tolerance induction.
Leukemia 20080701
-
Incisional surgical site infection in kidney transplantation.
Urology 20080701
-
Systemic inhibition of mammalian target of rapamycin inhibits fear memory reconsolidation.
Neurobiology of learning and memory 20080701
-
Treatment of in-stent restenosis with sirolimus-eluting-stents: results from the prospective German Cypher stent registry.
Clinical research in cardiology : official journal of the German Cardiac Society 20080701
-
Introduction: new insights, treatments, and management strategies for ADPKD.
Clinical journal of the American Society of Nephrology : CJASN 20080701
-
Sirolimus is associated with new-onset diabetes in kidney transplant recipients.
Journal of the American Society of Nephrology : JASN 20080701
-
Prospective randomized comparison of sirolimus- versus paclitaxel-eluting stents for the treatment of acute ST-elevation myocardial infarction: pROSIT trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080701
-
Fluvastatin synergistically improves the antiproliferative effect of everolimus on rat smooth muscle cells by altering p27Kip1/cyclin E expression.
Molecular pharmacology 20080701
-
Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer.
Autophagy 20080701
-
Caveolin-1 increases basal and TGF-beta1-induced expression of type I procollagen through PI-3 kinase/Akt/mTOR pathway in human dermal fibroblasts.
Cellular signalling 20080701
-
Leucine induces phosphorylation and activation of p70S6K in cortical neurons via the system L amino acid transporter.
Journal of neurochemistry 20080701
-
Rapamycin affects early fracture healing in mice.
British journal of pharmacology 20080701
-
Phase I, pharmacokinetic and pharmacodynamic study of the anti-insulinlike growth factor type 1 Receptor monoclonal antibody CP-751,871 in patients with multiple myeloma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080701
-
Inhibition of mTOR in combination with doxorubicin in an experimental model of hepatocellular carcinoma.
Journal of hepatology 20080701
-
Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma.
Journal of hepatology 20080701
-
Glibenclamide activates translation in rat pancreatic beta cells through calcium-dependent mTOR, PKA and MEK signalling pathways.
Diabetologia 20080701
-
Multivariate analysis applied to the study of spatial distributions found in drug-eluting stent coatings by confocal Raman microscopy.
Analytical chemistry 20080701
-
Mammalian target of rapamycin inhibitor dyslipidemia in kidney transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080701
-
Sirolimus may reduce fertility in male renal transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080701
-
Caffeine extends yeast lifespan by targeting TORC1.
Molecular microbiology 20080701
-
Evaluation of the variables characterized by significant discriminating power in the application of SIMCA classification method to proteomic studies.
Journal of proteome research 20080701
-
Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model.
The Journal of clinical investigation 20080701
-
Sirolimus-associated pneumonitis in heart transplant recipients.
The Annals of pharmacotherapy 20080701
-
Drug-eluting stents in ST elevation myocardial infarction: In light of the PROSIT trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080701
-
IL-1beta-driven ST2L expression promotes maturation resistance in rapamycin-conditioned dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 20080701
-
Intravascular ultrasound assessment of expansion of the sirolimus-eluting (cypher select) and paclitaxel-eluting (Taxus Express-2) stent in patients with diabetes mellitus.
The American journal of cardiology 20080701
-
Comparison of neointimal coverage by optical coherence tomography of a sirolimus-eluting stent versus a bare-metal stent three months after implantation.
The American journal of cardiology 20080701
-
Safety and efficacy of sirolimus-eluting stent in patients with acute coronary syndrome undergoing emergency procedure.
Circulation journal : official journal of the Japanese Circulation Society 20080701
-
Very late stent thrombosis associated with multiple stent fractures and peri-stent aneurysm formation after sirolimus-eluting stent implantation.
Circulation journal : official journal of the Japanese Circulation Society 20080701
-
Diabetes after transplantation and sirolimus: what's the connection?
Journal of the American Society of Nephrology : JASN 20080701
-
De-novo [corrected] post renal transplantation inflammatory bowel disease.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20080701
-
New drugs08, part 2.
Nursing 20080701
-
Everolimus-related pulmonary toxicity in heart transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080701
-
Renal cell carcinoma: the translation of molecular biology into new treatments, new patient outcomes, and nursing implications.
Oncology nursing forum 20080701
-
Corticosteroid interactions with cyclosporine, tacrolimus, mycophenolate, and sirolimus: fact or fiction?
The Annals of pharmacotherapy 20080701
-
[Targeted therapy for locally advanced and/or metastatic bladder cancer].
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20080701
-
Genetic interactions of MAF1 identify a role for Med20 in transcriptional repression of ribosomal protein genes.
PLoS genetics 20080701
-
Angiographic time course of in-stent restenosis with zotarolimus drug-eluting stents.
The Canadian journal of cardiology 20080701
-
Formation of tissue factor-factor VIIa-factor Xa complex induces activation of the mTOR pathway which regulates migration of human breast cancer cells.
Thrombosis and haemostasis 20080701
-
Variability in the prevalence of acute bronchoresponsiveness in different populations of patients with lymphangioleiomyomatosis.
Chest 20080701
-
Favorable results of concomitant tacrolimus and sirolimus therapy in Taiwanese renal transplant recipients at 12 months.
Journal of the Formosan Medical Association = Taiwan yi zhi 20080701
-
[Effeet of rapamycin on mTOR and eIF-4E expression in coxsackievirus B3-induced rat myocardial cells].
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20080701
-
Drug eluting stents: friend or foe? A review of cellular mechanisms behind the effects of Paclitaxel and sirolimus eluting stents.
Current drug metabolism 20080701
-
Oral everolimus inhibits neointimal proliferation in prosthetic pulmonary valved stents in pigs.
The Journal of heart valve disease 20080701
-
[Comparison of different drug-eluting stents in the treatment of coronary artery disease: a single center four-year clinical follow-up].
Zhonghua nei ke za zhi 20080701
-
Comparison of vascular response after sirolimus-eluting stent implantation between patients with unstable and stable angina pectoris: a serial optical coherence tomography study.
JACC. Cardiovascular imaging 20080701
-
Does underlying plaque morphology play a role in vessel healing after drug-eluting stent implantation?
JACC. Cardiovascular imaging 20080701
-
Cyclosporine A and Rapamycin induce in vitro cholesteryl ester transfer protein activity, and suppress lipoprotein lipase activity in human plasma.
International journal of pharmaceutics 20080624
-
Clinical efficacy of drug-eluting stents in diabetic patients: a meta-analysis.
Journal of the American College of Cardiology 20080624
-
Novel genetically encoded biosensors using firefly luciferase.
ACS chemical biology 20080620
-
Delivery of rapamycin-loaded nanoparticle down regulates ICAM-1 expression and maintains an immunosuppressive profile in human CD34+ progenitor-derived dendritic cells.
Journal of biomedical materials research. Part A 20080615
-
Development of a novel biocompatible polymer system for extended drug release in a next-generation drug-eluting stent.
Journal of biomedical materials research. Part A 20080615
-
Impact of stent deployment procedural factors on long-term effectiveness and safety of sirolimus-eluting stents (final results of the multicenter prospective STLLR trial).
The American journal of cardiology 20080615
-
Protein phosphatase 2A and rapamycin regulate the nuclear localization and activity of the transcription factor GLI3.
Cancer research 20080615
-
PTEN loss does not predict for response to RAD001 (Everolimus) in a glioblastoma orthotopic xenograft test panel.
Clinical cancer research : an official journal of the American Association for Cancer Research 20080615
-
The forgotten player of in-stent restenosis: endothelial dysfunction.
International journal of cardiology 20080606
-
Reduced exposure to calcineurin inhibitors in renal transplantation.
The New England journal of medicine 20080605
-
Differential effects of ketoconazole on exposure to temsirolimus following intravenous infusion of temsirolimus.
British journal of cancer 20080603
-
Differential effects of drug-eluting stents on local endothelium-dependent coronary vasomotion.
Journal of the American College of Cardiology 20080603
-
Sirolimus-induced vascular dysfunction. Increased mitochondrial and nicotinamide adenosine dinucleotide phosphate oxidase-dependent superoxide production and decreased vascular nitric oxide formation.
Journal of the American College of Cardiology 20080603
-
Endothelial dysfunction associated with drug-eluting stents what, where, when, and how?
Journal of the American College of Cardiology 20080603
-
Contribution of organized thrombus to in-stent restenosis after sirolimus-eluting stent implantation: optical coherence tomography findings.
European heart journal 20080601
-
Sirolimus and intraoperative hyperthermic peritoneal chemoperfusion with mitomycin-C do not impair healing of bowel anastomoses.
Transplant international : official journal of the European Society for Organ Transplantation 20080601
-
In human endothelial cells rapamycin causes mTORC2 inhibition and impairs cell viability and function.
Cardiovascular research 20080601
-
Immunosuppressive medications, clinical and metabolic parameters in new-onset diabetes mellitus after kidney transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20080601
-
Everolimus for refractory Crohn's disease: a case report.
Inflammatory bowel diseases 20080601
-
Inhibition of mTOR by sirolimus induces remission of post-transplant lymphoproliferative disorders.
Transplant international : official journal of the European Society for Organ Transplantation 20080601
-
Combination of rapamycin and IL-2 increases de novo induction of human CD4(+)CD25(+)FOXP3(+) T cells.
Journal of autoimmunity 20080601
-
Response of human renal tubular cells to cyclosporine and sirolimus: a toxicogenomic study.
Toxicology and applied pharmacology 20080601
-
Long-term efficacy and safety of a calcineurin inhibitor-free regimen in live-donor renal transplant recipients.
Journal of the American Society of Nephrology : JASN 20080601
-
Effect of Paclitaxel-eluting versus sirolimus-eluting stents on coronary restenosis in Korean diabetic patients.
Journal of interventional cardiology 20080601
-
Graft rejection: pharmacogenetic analysis or drug anamnesis?
British journal of clinical pharmacology 20080601
-
Simultaneous quantification of cyclosporine, tacrolimus, sirolimus and everolimus in whole blood by liquid chromatography-electrospray mass spectrometry.
Clinical biochemistry 20080601
-
RAD001 (Everolimus) inhibits growth of prostate cancer in the bone and the inhibitory effects are increased by combination with docetaxel and zoledronic acid.
The Prostate 20080601
-
Lithium-mediated suppression of morphogenesis and growth in Candida albicans.
FEMS yeast research 20080601
-
Difficult stent delivery: use of an aspiration catheter as a 'sheath'.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080601
-
Comparison of Akt/mTOR signaling in primary breast tumors and matched distant metastases.
Cancer 20080601
-
Long-term clinical outcomes of real-world experience using sirolimus-eluting stents in saphenous vein graft disease.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080601
-
Safety of drug-eluting stents.
Nature clinical practice. Cardiovascular medicine 20080601
-
Rapamycin conditionally inhibits Hsp90 but not Hsp70 mRNA translation in Drosophila: implications for the mechanisms of Hsp mRNA translation.
Cell stress & chaperones 20080601
-
Regulated insulin delivery from human epidermal cells reverses hyperglycemia.
Molecular therapy : the journal of the American Society of Gene Therapy 20080601
-
Rapamycin treatment for a child with germline PTEN mutation.
Nature clinical practice. Oncology 20080601
-
Pharmacodynamic effects of everolimus on anti-CD3 antibody-stimulated T-lymphocyte proliferation and interleukin-10 synthesis in stable kidney-transplant patients.
Cytokine 20080601
-
Expression of c-Kit isoforms in multiple myeloma: differences in signaling and drug sensitivity.
Haematologica 20080601
-
An Epstein-Barr virus positive natural killer lymphoma xenograft derived for drug testing.
Leukemia & lymphoma 20080601
-
Autophagy activation by rapamycin eliminates mouse Mallory-Denk bodies and blocks their proteasome inhibitor-mediated formation.
Hepatology (Baltimore, Md.) 20080601
-
Multicenter trial of everolimus in pediatric renal transplant recipients: results at three year.
Pediatric transplantation 20080601
-
Study comparing the double kissing (DK) crush with classical crush for the treatment of coronary bifurcation lesions: the DKCRUSH-1 Bifurcation Study with drug-eluting stents.
European journal of clinical investigation 20080601
-
Impact of body mass index on the one-year clinical outcome of patients undergoing multivessel revascularization with sirolimus-eluting stents (from the Arterial Revascularization Therapies Study Part II).
The American journal of cardiology 20080601
-
Comparison of effectiveness and safety of sirolimus-eluting stents versus bare-metal stents in patients with diabetes mellitus (from the Italian Multicenter Randomized DESSERT Study).
The American journal of cardiology 20080601
-
Differential involvement of IkappaB kinases alpha and beta in cytokine- and insulin-induced mammalian target of rapamycin activation determined by Akt.
Journal of immunology (Baltimore, Md. : 1950) 20080601
-
Drug reactions - new observations.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20080601
-
Drug-eluting stent in saphenous vein graft lesions.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080601
-
Platelet glycoprotein IIb/IIIa receptor inhibitors: is their future as bright as their past?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080601
-
Impact of platelet glycoprotein IIb/IIIa receptor inhibitors on outcomes of diabetic patients undergoing percutaneous coronary interventions using sirolimus-eluting stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080601
-
Angiographic and clinical outcomes after sirolimus-eluting stent implantation to de novo ostial lesion of the right coronary artery: a retrospective study.
Circulation journal : official journal of the Japanese Circulation Society 20080601
-
Sirolimus-eluting stents suppress neointimal formation irrespective of metallic allergy.
Circulation journal : official journal of the Japanese Circulation Society 20080601
-
Concurrent administration of sirolimus and voriconazole: a pilot study assessing safety and approaches to appropriate management.
Pharmacotherapy 20080601
-
Preliminary study of the use of drug-eluting stents in atherosclerotic renal artery stenoses 4 mm in diameter or smaller.
Journal of vascular and interventional radiology : JVIR 20080601
-
Safety and efficacy of overlapping sirolimus-eluting versus paclitaxel-eluting stents.
American heart journal 20080601
-
Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK.
Genes & development 20080601
-
Human melanoma cytolysis by combined inhibition of mammalian target of rapamycin and vascular endothelial growth factor/vascular endothelial growth factor receptor-2.
Cancer research 20080601
-
Changes in tumor metabolism as readout for Mammalian target of rapamycin kinase inhibition by rapamycin in glioblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20080601
-
Combination strategy targeting the hypoxia inducible factor-1 alpha with mammalian target of rapamycin and histone deacetylase inhibitors.
Clinical cancer research : an official journal of the American Association for Cancer Research 20080601
-
Very late sirolimus-eluting stent displaced fracture in the mid-left anterior descending artery.
The Journal of invasive cardiology 20080601
-
Midterm results of a sirolimus-eluting stent implanted for recurrent carotid in-stent restenosis.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20080601
-
A novel bioengineered small-caliber vascular graft incorporating heparin and sirolimus: excellent 6-month patency.
The Journal of thoracic and cardiovascular surgery 20080601
-
Failure of immunosuppressive drug levels to predict T-cell reactivity in pediatric transplant patients.
Journal of pediatric surgery 20080601
-
Mammalian target of rapamycin inhibition as a therapeutic strategy in the management of urologic malignancies.
Molecular cancer therapeutics 20080601
-
Intrinsically lower AKT, mammalian target of rapamycin, and hypoxia-inducible factor activity correlates with increased sensitivity to 2-deoxy-D-glucose under hypoxia in lung cancer cell lines.
Molecular cancer therapeutics 20080601
-
Reduced risk of cytomegalovirus infection in solid organ transplant recipients treated with sirolimus: a pooled analysis of clinical trials.
Transplantation proceedings 20080601
-
Observation of efficacy and safety of converting the calcineurin inhibitor to sirolimus in renal transplant recipients with chronic allograft nephropathy.
Transplantation proceedings 20080601
-
The impact of conversion from mycophenolate mofetil to mycophenolate sodium among renal transplant recipients on a sirolimus-based regimen.
Transplantation proceedings 20080601
-
Sirolimus-based immunosuppressive therapy in liver transplant recipient with tacrolimus-related chronic renal insufficiency.
Transplantation proceedings 20080601
-
Demyelinating sensorimotor polyneuropathy associated with the use of sirolimus: a case report.
Transplantation proceedings 20080601
-
Rapamycin, mycophenolate mofetil, methylprednisolone, and cytotoxic T-lymphocyte-associated antigen 4 immunoglobulin-based conditioning regimen to induce partial tolerance to hind limb allografts without cytoreductive conditioning.
Transplantation proceedings 20080601
-
Antiproliferative and overadditive effects of rapamycin and FTY720 in pancreatic cancer cells in vitro.
Transplantation proceedings 20080601
-
Case report: successful treatment of posttransplant lymphoproliferative disorder and quiescence of dermatomyositis with rituximab and sirolimus.
Transplantation proceedings 20080601
-
Chylous ascites in a renal transplant recipient under sirolimus (rapamycin) treatment.
Transplantation proceedings 20080601
-
Everolimus: an update on the mechanism of action, pharmacokinetics and recent clinical trials.
Expert opinion on drug metabolism & toxicology 20080601
-
Short-term Efficacy of Topical Immunosuppressive Agents on the Survival of Cultivated Allo-Conjunctival Equivalents.
Korean journal of ophthalmology : KJO 20080601
-
A retrospective study of conversion from tacrolimus-based to sirolimus-based immunosuppression in orthotopic liver transplant recipients.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20080601
-
[Recent progress in the study on antitumor drugs targeting hypoxia-inducible factor-1].
Yao xue xue bao = Acta pharmaceutica Sinica 20080601
-
[Side branch occlusion rate at sites of overlapping sirolimus- or paclitaxel-eluting stents for treating long coronary lesions].
Zhonghua xin xue guan bing za zhi 20080601
-
Abnormal vasomotor function of porcine coronary arteries distal to sirolimus-eluting stents.
JACC. Cardiovascular interventions 20080601
-
AMP-activated protein kinase is essential for survival in chronic hypoxia.
Biochemical and biophysical research communications 20080530
-
Randomized trial of single-dose versus divided-dose rabbit anti-thymocyte globulin induction in renal transplantation: an interim report.
Transplantation 20080527
-
Long-term outcome in patients treated with sirolimus-eluting stents in complex coronary artery lesions: 3-year results of the SCANDSTENT (Stenting Coronary Arteries in Non-Stress/Benestent Disease) trial.
Journal of the American College of Cardiology 20080527
-
Aminoacyl-tRNA synthetase inhibitors as potent and synergistic immunosuppressants.
Journal of medicinal chemistry 20080522
-
DTCA for PTCA--crossing the line in consumer health education?
The New England journal of medicine 20080522
-
Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20080521
-
Mammalian target of rapamycin contributes to the acquired apoptotic resistance of human mesothelioma multicellular spheroids.
The Journal of biological chemistry 20080509
-
Synthesis and drug release properties of poly(ethylene oxide) segmented polysulfone copolymers.
Journal of controlled release : official journal of the Controlled Release Society 20080508
-
[Drug-eluting stent-associated thrombosis: clinical relevance of impaired vessel-wall healing].
Postepy higieny i medycyny doswiadczalnej (Online) 20080508
-
Study power in the SORT OUT II trial.
JAMA 20080507
-
Epstein Barr virus induced lymphoma in a child with IPEX syndrome.
Pediatric blood & cancer 20080501
-
Low dose rapamycin does not modulate p-glycoprotein function in acute myeloid leukaemia.
Leukemia research 20080501
-
Neointimal coverage of bare-metal and sirolimus-eluting stents evaluated with optical coherence tomography.
Heart (British Cardiac Society) 20080501
-
Prevention of atherosclerosis by the mTOR inhibitor everolimus in LDLR-/- mice despite severe hypercholesterolemia.
Atherosclerosis 20080501
-
Selective inhibition of SCLC growth by the A12 anti-IGF-1R monoclonal antibody correlates with inhibition of Akt.
Lung cancer (Amsterdam, Netherlands) 20080501
-
Inhibitors of mammalian target of rapamycin downregulate MYCN protein expression and inhibit neuroblastoma growth in vitro and in vivo.
Oncogene 20080501
-
Insulin-like growth factor-1 (IGF-1) and leucine activate pig myogenic satellite cells through mammalian target of rapamycin (mTOR) pathway.
Molecular reproduction and development 20080501
-
Toxicities associated with the administration of sorafenib, sunitinib, and temsirolimus and their management in patients with metastatic renal cell carcinoma.
European urology 20080501
-
Effects of stem cell therapy with G-CSF on coronary artery after drug-eluting stent implantation in patients with acute myocardial infarction.
Heart (British Cardiac Society) 20080501
-
Accuracy and variability of equations to estimate glomerular filtration rates in renal transplant patients receiving sirolimus and/or calcineurin inhibitor immunosuppression.
Transplant international : official journal of the European Society for Organ Transplantation 20080501
-
Nitric oxide mediates NMDA-induced persistent inhibition of protein synthesis through dephosphorylation of eukaryotic initiation factor 4E-binding protein 1 and eukaryotic initiation factor 4G proteolysis.
The Biochemical journal 20080501
-
Autophagy plays a protective role during zVAD-induced necrotic cell death.
Autophagy 20080501
-
Combined treatment with triptolide and rapamycin prolongs graft survival in a mouse model of cardiac transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20080501
-
Induction of transplantation tolerance by combining non-myeloablative conditioning with delivery of alloantigen by T cells.
Clinical immunology (Orlando, Fla.) 20080501
-
Intramural delivery of rapamycin with alphavbeta3-targeted paramagnetic nanoparticles inhibits stenosis after balloon injury.
Arteriosclerosis, thrombosis, and vascular biology 20080501
-
Sirolimus-based immunosuppression following liver transplantation for hepatocellular carcinoma.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20080501
-
Rapamycin suppresses TLR4-triggered IL-6 and PGE(2) production of colon cancer cells by inhibiting TLR4 expression and NF-kappaB activation.
Molecular immunology 20080501
-
Renal cell carcinoma.
Current opinion in oncology 20080501
-
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway.
Nature chemical biology 20080501
-
Impact of rapamycin on liver regeneration.
Virchows Archiv : an international journal of pathology 20080501
-
Leucine-enriched nutrients and the regulation of mammalian target of rapamycin signalling and human skeletal muscle protein synthesis.
Current opinion in clinical nutrition and metabolic care 20080501
-
Sirolimus in combination with cyclosporine or tacrolimus plus methotrexate for prevention of graft-versus-host disease following hematopoietic cell transplantation from unrelated donors.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080501
-
Incidence of PTLD in pediatric renal transplant recipients receiving basiliximab, calcineurin inhibitor, sirolimus and steroids.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080501
-
Amelioration of protein misfolding disease by rapamycin: translation or autophagy?
Autophagy 20080501
-
Nanomedicine captures cardiovascular disease.
Arteriosclerosis, thrombosis, and vascular biology 20080501
-
Cutting edge: Foxp3-mediated induction of pim 2 allows human T regulatory cells to preferentially expand in rapamycin.
Journal of immunology (Baltimore, Md. : 1950) 20080501
-
Constitutive activation of p70 S6 kinase is associated with intrinsic resistance to cisplatin.
International journal of oncology 20080501
-
Islet transplantation in patients with autoimmune diabetes induces homeostatic cytokines that expand autoreactive memory T cells.
The Journal of clinical investigation 20080501
-
Sirolimus conversion for renal preservation in liver transplantation: not so fast.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20080501
-
Sirolimus in liver transplant recipients with renal dysfunction offers no advantage over low-dose calcineurin inhibitor regimens.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20080501
-
Overproduction of non-translatable mRNA silences. The transcription of Ty1 retrotransposons in S. cerevisiae via functional inactivation of the nuclear cap-binding complex and subsequent hyperstimulation of the TORC1 pathway.
Yeast (Chichester, England) 20080501
-
Outcomes after sirolimus- and paclitaxel-eluting stent implantation in patients with insulin-treated diabetes mellitus.
The American journal of cardiology 20080501
-
Effect of rapamycin therapy on coronary artery physiology early after cardiac transplantation.
American heart journal 20080501
-
Sirolimus for lymphangioleiomyomatosis lesions.
The New England journal of medicine 20080501
-
Loss of tuberous sclerosis complex-2 function and activation of mammalian target of rapamycin signaling in endometrial carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20080501
-
A phase 2 clinical trial of deforolimus (AP23573, MK-8669), a novel mammalian target of rapamycin inhibitor, in patients with relapsed or refractory hematologic malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 20080501
-
Coronary aneurysm formation in a patient early after everolimus-eluting stent implantation.
The Journal of invasive cardiology 20080501
-
[Coronary artery bypass grafting for simultaneous subacute stent thrombosis after sirolimus-eluting stent implantation].
Kyobu geka. The Japanese journal of thoracic surgery 20080501
-
Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors.
Molecular cancer therapeutics 20080501
-
Kaposi's sarcoma resolves after sirolimus therapy in a patient with pemphigus vulgaris.
Archives of dermatology 20080501
-
Classic Mediterranean Kaposi's sarcoma regression with sirolimus treatment.
Archives of dermatology 20080501
-
Molecular target therapies in endometrial cancer: from the basic research to the clinic.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20080501
-
Polycystic kidney disease: will it become treatable?
Polskie Archiwum Medycyny Wewnetrznej 20080501
-
[Use of Sirolimus in five pediatric patients undergoing solid organ transplantation].
Revista medica de Chile 20080501
-
EXCELLA First-in-Man (FIM) study: safety and efficacy of novolimus-eluting stent in de novo coronary lesions.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080501
-
Biodegradable-polymer-based, sirolimus-eluting Supralimus stent: 6-month angiographic and 30-month clinical follow-up results from the series I prospective study.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080501
-
Novel drug eluting stent system for customised treatment of coronary lesions: CUSTOM I feasibility trial 24 month results.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080501
-
Kidney transplant histology after one year of continuous therapy with sirolimus compared with tacrolimus.
Transplantation 20080427
-
The incidence and clinical impact of stent strut fractures developed after drug-eluting stent implantation.
International journal of cardiology 20080425
-
Safety and efficacy of the CYPHER Select Sirolimus-eluting stent in the 'Real World'--clinical and angiographic results from the China CYPHER Select registry.
International journal of cardiology 20080425
-
Comparison of an everolimus-eluting stent and a paclitaxel-eluting stent in patients with coronary artery disease: a randomized trial.
JAMA 20080423
-
Next-generation drug-eluting stents: a spirited step forward or more of the same.
JAMA 20080423
-
Four-year clinical follow-up of the rapamycin-eluting stent evaluated at Rotterdam Cardiology Hospital registry.
The American journal of cardiology 20080415
-
Carcinoma 'en Cuirasse' from cutaneous squamous cell carcinoma in a renal transplant patient.
Transplantation 20080415
-
Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma.
Cancer research 20080415
-
A new pharmacologic action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis.
Cancer research 20080415
-
Tor pathway control of the nitrogen-responsive DAL5 gene bifurcates at the level of Gln3 and Gat1 regulation in Saccharomyces cerevisiae.
The Journal of biological chemistry 20080404
-
The PtdIns(4,5)P2 ligand itself influences the localization of PKCalpha in the plasma membrane of intact living cells.
Journal of molecular biology 20080404
-
Initial testing (stage 1) of the mTOR inhibitor rapamycin by the pediatric preclinical testing program.
Pediatric blood & cancer 20080401
-
Quantitative spatial distribution of sirolimus and polymers in drug-eluting stents using confocal Raman microscopy.
Journal of biomedical materials research. Part A 20080401
-
mTOR is activated in the majority of malignant melanomas.
The Journal of investigative dermatology 20080401
-
Drug-eluting stents in renal artery stenosis.
European radiology 20080401
-
GLN3 encodes a global regulator of nitrogen metabolism and virulence of C. albicans.
Fungal genetics and biology : FG & B 20080401
-
Assessment of potential relationship between wall shear stress and arterial wall response after bare metal stent and sirolimus-eluting stent implantation in patients with diabetes mellitus.
The international journal of cardiovascular imaging 20080401
-
[Renal cell carcinoma and antiangiogenic therapies].
Presse medicale (Paris, France : 1983) 20080401
-
Evaluation of the dedicated Frontier coronary bifurcation stent: A matched pair analysis with drug-eluting and bare metal stents.
Clinical research in cardiology : official journal of the German Cardiac Society 20080401
-
Sirolimus-eluting stents in the treatment of chronic total coronary occlusions: results from the prospective multi-center German Cypher Stent Registry.
Clinical research in cardiology : official journal of the German Cardiac Society 20080401
-
Rapamycin modulates the eNOS vs. shear stress relationship.
Cardiovascular research 20080401
-
mTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes.
Diabetes 20080401
-
The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes.
Traffic (Copenhagen, Denmark) 20080401
-
Modulation of Na+-Ca2+ exchanger expression by immunosuppressive drugs is isoform-specific.
Molecular pharmacology 20080401
-
Rapamycin inhibits polyglutamine aggregation independently of autophagy by reducing protein synthesis.
Molecular pharmacology 20080401
-
Roles of autophagy and mTOR signaling in neuronal differentiation of mouse neuroblastoma cells.
Cellular signalling 20080401
-
Hypoxia stimulus: An adaptive immune response during dendritic cell maturation.
Kidney international 20080401
-
Strategies to induce marked prolongation of secondary skin allograft survival in alloantigen-primed mice.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080401
-
Development of proteinuria after switch to sirolimus-based immunosuppression in long-term cardiac transplant patients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080401
-
CD4+ CD25+ FOXP3+ regulatory T cells increase de novo in kidney transplant patients after immunodepletion with Campath-1H.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080401
-
Long-term effects of rapamycin treatment on insulin mediated phosphorylation of Akt/PKB and glycogen synthase activity.
Experimental cell research 20080401
-
Trends in adult post-kidney transplant immunosuppressive use in Australia, 1991-2005.
Nephrology (Carlton, Vic.) 20080401
-
Long-term clinical outcomes after sirolimus-eluting stent implantation for treatment of restenosis within bare-metal versus drug-eluting stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401
-
Identifying optimal biologic doses of everolimus (RAD001) in patients with cancer based on the modeling of preclinical and clinical pharmacokinetic and pharmacodynamic data.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080401
-
Dose- and schedule-dependent inhibition of the mammalian target of rapamycin pathway with everolimus: a phase I tumor pharmacodynamic study in patients with advanced solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080401
-
Phase I pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080401
-
Evaluation and management of steroid-unresponsive nephrotic syndrome.
Current opinion in pediatrics 20080401
-
Very very late thrombosis of a sirolimus-eluting stent: does suboptimal stent expansion take its toll even after three years?
Journal of cardiovascular medicine (Hagerstown, Md.) 20080401
-
Simultaneous subacute coronary drug-eluting stent thrombosis in two different vessels of a patient with factor V Leiden mutation.
Journal of cardiovascular medicine (Hagerstown, Md.) 20080401
-
Short-period hypoxia increases mouse embryonic stem cell proliferation through cooperation of arachidonic acid and PI3K/Akt signalling pathways.
Cell proliferation 20080401
-
Acute allograft rejection and immunosuppression: influence on endogenous melatonin secretion.
Journal of pineal research 20080401
-
Temsirolimus downregulates p21 without altering cyclin D1 expression and induces autophagy and synergizes with vorinostat in mantle cell lymphoma.
Experimental hematology 20080401
-
Activation and function of the mTORC1 pathway in mast cells.
Journal of immunology (Baltimore, Md. : 1950) 20080401
-
Antiproliferative effect of rapamycin on human T-cell leukemia cell line Jurkat by cell cycle arrest and telomerase inhibition.
Acta pharmacologica Sinica 20080401
-
Long-term (>3 Years) outcome and predictors of clinical events after insertion of sirolimus-eluting stent in one or more native coronary arteries (from the Israeli arm of the e-Cypher registry).
The American journal of cardiology 20080401
-
Rapamycin and tuberous sclerosis complex: from Easter Island to epilepsy.
Annals of neurology 20080401
-
Treatment of drug-eluting stent restenosis: a sandwich may not be the best combo.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401
-
Stent fracture, an incidental finding or a significant marker of clinical in-stent restenosis?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401
-
Stent strut fracture: seeing is believing.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401
-
Survival advantage in Medicare patients receiving drug-eluting stents compared with bare metal stents: real or artefactual?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401
-
DES editorial. Is there a survival benefit?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401
-
Effect of lumen narrowing within sirolimus-eluting stents on proximal and distal vessel segments.
Circulation journal : official journal of the Japanese Circulation Society 20080401
-
Pharmacokinetics of mycophenolate mofetil and sirolimus in children.
Therapeutic drug monitoring 20080401
-
Role of pharmacogenetics of immunosuppressive drugs in organ transplantation.
Therapeutic drug monitoring 20080401
-
Toxicodynamic therapeutic drug monitoring of immunosuppressants: promises, reality, and challenges.
Therapeutic drug monitoring 20080401
-
The effect of drug-eluting stents on intermediate angiographic and clinical outcomes in diabetic patients: insights from randomized clinical trials.
American heart journal 20080401
-
P70 S6 kinase negatively regulates fibroblast growth factor 2-stimulated interleukin-6 synthesis in osteoblasts: function at a point downstream from protein kinase C.
The Journal of endocrinology 20080401
-
Effects of cyclosporine, tacrolimus and sirolimus on vascular changes related to immune response.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080401
-
Regression of pulmonary lymphangioleiomyomatosis (PLAM)-associated retroperitoneal angiomyolipoma post-lung transplantation with rapamycin treatment.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080401
-
Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy.
Cancer research 20080401
-
Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex.
Annals of neurology 20080401
-
Rapid activation of Akt2 is sufficient to stimulate GLUT4 translocation in 3T3-L1 adipocytes.
Cell metabolism 20080401
-
Treatment options for metastatic renal cell carcinoma: a review.
The Canadian journal of urology 20080401
-
Rapamycin prevents the development of nephritis in lupus-prone NZB/W F1 mice.
Lupus 20080401
-
Preclinical evidences suggest new treatment options for endocrine disorders: Pasireotide (SOM230) and Everolimus (RAD001).
Annales d'endocrinologie 20080401
-
Conversion therapy to everolimus in renal transplant recipients: results after one year.
Transplantation proceedings 20080401
-
Drug-eluting stents: present and future.
Cardiovascular & hematological agents in medicinal chemistry 20080401
-
Polypyrimidine tract-binding protein is involved in regulation of albumin synthesis in response to food intake.
Journal of nutritional science and vitaminology 20080401
-
Results of provisional stenting with a Sirolimus-eluting stent for bifurcation lesion: multicenter study in Japan.
Journal of cardiology 20080401
-
[Coronary angioplasty in the real world: the RESTEM registry. Outcome of patients treated with sirolimus-eluting stents].
Giornale italiano di cardiologia (2006) 20080401
-
mToR inhibitors-induced proteinuria: mechanisms, significance, and management.
Transplantation reviews (Orlando, Fla.) 20080401
-
Drug-eluting versus bare-metal stents in the treatment of patients with ST-segment elevation myocardial infarction.
JACC. Cardiovascular interventions 20080401
-
Should we routinely use drug-eluting stents for acute myocardial infarction? Let's wait and see.
JACC. Cardiovascular interventions 20080401
-
Stent malapposition after sirolimus-eluting and bare-metal stent implantation in patients with ST-segment elevation myocardial infarction: acute and 9-month intravascular ultrasound results of the MISSION! intervention study.
JACC. Cardiovascular interventions 20080401
-
Drug essentials mTOR inhibitors.
Oncology (Williston Park, N.Y.) 20080401
-
Human immunodeficiency virus type-1 infection inhibits autophagy.
AIDS (London, England) 20080330
-
Intravascular ultrasound findings in patients with restenosis of sirolimus- and paclitaxel-eluting stents.
International journal of cardiology 20080328
-
Impact of significant chronic kidney disease on long-term clinical outcomes after drug-eluting stent versus bare metal stent implantation.
International journal of cardiology 20080328
-
Impact of immunosuppressive drugs on CD4+CD25+FOXP3+ regulatory T cells: does in vitro evidence translate to the clinical setting?
Transplantation 20080327
-
Multicenter, randomized study of the use of everolimus with tacrolimus after renal transplantation demonstrates its effectiveness.
Transplantation 20080327
-
Asymmetric dimethylarginine and cardiac allograft vasculopathy progression: modulation by sirolimus.
Transplantation 20080327
-
Novel immunosuppression: R348, a JAK3- and Syk-inhibitor attenuates acute cardiac allograft rejection.
Transplantation 20080327
-
Overview of the 2007 Food and Drug Administration Circulatory System Devices Panel meeting on the endeavor zotarolimus-eluting coronary stent.
Circulation 20080325
-
Sirolimus-eluting cobalt-chromium stents: two-year clinical results from first-in-man study on the Firebird 2 stent.
Chinese medical journal 20080320
-
Neointimal coverage of sirolimus-eluting stents 6 months and 12 months after implantation: evaluation by optical coherence tomography.
Chinese medical journal 20080320
-
Crush stenting in treating coronary bifurcate lesions: paclitaxel eluting stents versus sirolimus eluting stents.
Chinese medical journal 20080320
-
Inflammatory response, drug-eluting stent and restenosis.
Chinese medical journal 20080320
-
Delivery of rapamycin by PLGA nanoparticles enhances its suppressive activity on dendritic cells.
Journal of biomedical materials research. Part A 20080315
-
Effectiveness of drug-eluting stent implantation for patients with unprotected left main coronary artery stenosis.
The American journal of cardiology 20080315
-
Mammalian target of rapamycin repression by 3,3'-diindolylmethane inhibits invasion and angiogenesis in platelet-derived growth factor-D-overexpressing PC3 cells.
Cancer research 20080315
-
Biodegradable drug-eluting stents: promises and pitfalls.
Lancet (London, England) 20080315
-
Decision time for pancreatic islet-cell transplantation.
Lancet (London, England) 20080315
-
A bioabsorbable everolimus-eluting coronary stent system for patients with single de-novo coronary artery lesions (ABSORB): a prospective open-label trial.
Lancet (London, England) 20080315
-
Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis.
Molecular cell 20080314
-
Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumours sensitive and resistant to anti-EGFR drugs.
British journal of cancer 20080311
-
Drug-eluting stent thrombosis: results from the multicenter Spanish registry ESTROFA (Estudio ESpañol sobre TROmbosis de stents FArmacoactivos).
Journal of the American College of Cardiology 20080311
-
Long-term follow-up evaluation after sirolimus-eluting stent implantation by optical coherence tomography: do uncovered struts persist?
Journal of the American College of Cardiology 20080304
-
Chemical imaging of drug eluting coatings: combining surface analysis and confocal Raman microscopy.
Journal of controlled release : official journal of the Controlled Release Society 20080303
-
Impact of late incomplete stent apposition after sirolimus-eluting stent implantation on 4-year clinical events: intravascular ultrasound analysis from the multicentre, randomised, RAVEL, E-SIRIUS and SIRIUS trials.
Heart (British Cardiac Society) 20080301
-
Subversion of cellular autophagy by Anaplasma phagocytophilum.
Cellular microbiology 20080301
-
Components of the Vid30c are needed for the rapamycin-induced degradation of the high-affinity hexose transporter Hxt7p in Saccharomyces cerevisiae.
FEMS yeast research 20080301
-
On the participation of mTOR in recognition memory.
Neurobiology of learning and memory 20080301
-
Mitogen-stimulated and rapamycin-sensitive glucose transporter 12 targeting and functional glucose transport in renal epithelial cells.
Endocrinology 20080301
-
Sirolimus ameliorates the enhanced expression of metalloproteinases in a rat model of autosomal dominant polycystic kidney disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080301
-
Immunosuppression and tumor development in organ transplant recipients: the emerging dualistic role of rapamycin.
Transplant international : official journal of the European Society for Organ Transplantation 20080301
-
Synergistic effect of mTOR inhibitor rapamycin and fluorouracil in inducing apoptosis and cell senescence in hepatocarcinoma cells.
Cancer biology & therapy 20080301
-
Targeting 14-3-3 sensitizes native and mutant BCR-ABL to inhibition with U0126, rapamycin and Bcl-2 inhibitor GX15-070.
Leukemia 20080301
-
Interferon beta augments tuberous sclerosis complex 2 (TSC2)-dependent inhibition of TSC2-null ELT3 and human lymphangioleiomyomatosis-derived cell proliferation.
Molecular pharmacology 20080301
-
Phospho-S6 ribosomal protein: a potential new predictive sarcoma marker for targeted mTOR therapy.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20080301
-
Synergic antiproliferative and antiangiogenic effects of EGFR and mTor inhibitors on pancreatic cancer cells.
Biochemical pharmacology 20080301
-
Sirolimus reduces polycystic liver volume in ADPKD patients.
Journal of the American Society of Nephrology : JASN 20080301
-
Pharmacokinetics of sirolimus (rapamycin) in subjects with severe hepatic impairment.
Journal of clinical pharmacology 20080301
-
Delta-24-RGD in combination with RAD001 induces enhanced anti-glioma effect via autophagic cell death.
Molecular therapy : the journal of the American Society of Gene Therapy 20080301
-
Human herpesvirus-8 (HHV-8)-associated primary effusion lymphoma in two renal transplant recipients receiving rapamycin.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080301
-
mTOR signaling contributes to chondrocyte differentiation.
Developmental dynamics : an official publication of the American Association of Anatomists 20080301
-
STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25- effector T cells.
International immunology 20080301
-
Two-year clinical outcome after implantation of sirolimus-eluting and paclitaxel-eluting stents in diabetic patients.
European heart journal 20080301
-
Late incomplete stent apposition after drug-eluting stent implantation: a true risk factor or 'an innocent bystander'?
Heart (British Cardiac Society) 20080301
-
Luminal narrowing after sirolimus-eluting stent implantation for in-stent restenosis using intravascular ultrasound.
American heart journal 20080301
-
Immediate and long-term outcomes of drug-eluting stent implantation for unprotected left main coronary artery disease: comparison with bare-metal stent implantation.
American heart journal 20080301
-
Biological action of rapamycin in renal transplantation.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20080301
-
Clinical safety of drug-eluting stents in the Korea acute myocardial infarction registry.
Circulation journal : official journal of the Japanese Circulation Society 20080301
-
Inflammation and delayed endothelization with overlapping drug-eluting stents in a porcine model of in-stent restenosis.
Circulation journal : official journal of the Japanese Circulation Society 20080301
-
Higher incidence and serum levels of minor cardiac biomarker elevation in sirolimus-eluting stent (Cypher) than bare metal stent implantations.
Coronary artery disease 20080301
-
Differential outcomes after sirolimus-eluting stent implantation: comparing on-label versus off-label patients in the 'real world'.
Coronary artery disease 20080301
-
Exploiting the mammalian target of rapamycin pathway in hematologic malignancies.
Current opinion in hematology 20080301
-
Vascular endothelial growth factor protein levels and gene expression in peripheral monocytes after stenting: a randomized comparative study of sirolimus: eluting and bare metal stents.
European heart journal 20080301
-
Unprotected left main disease managed with drug-eluting stents: long-term outcome of 100 patients with increased surgical risk.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080301
-
Outcomes of nonagenarians who undergo percutaneous coronary intervention with drug-eluting stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080301
-
Percutaneous coronary intervention in nonagenarians: age before beauty?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080301
-
Stenting unprotected left main: the outcome is not always favorable.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080301
-
Antitumor activity of rapamycin and octreotide as single agents or in combination in neuroendocrine tumors.
Endocrine-related cancer 20080301
-
Temsirolimus, an inhibitor of mammalian target of rapamycin.
Clinical cancer research : an official journal of the American Association for Cancer Research 20080301
-
Preclinical cancer therapy in a mouse model of neurofibromatosis-1 optic glioma.
Cancer research 20080301
-
Damage to polymer of undelivered sirolimus-eluting stents.
The Journal of invasive cardiology 20080301
-
Intervention of stenosed right coronary artery and anomalous left main coronary artery: single main coronary trunk.
The Journal of invasive cardiology 20080301
-
FK506 binding protein mediates glioma cell growth and sensitivity to rapamycin treatment by regulating NF-kappaB signaling pathway.
Neoplasia (New York, N.Y.) 20080301
-
A new trick for an old drug: mTOR inhibitor rapamycin augments the effect of fluorouracil on hepatocellular carcinoma by inducing cell senescence.
Cancer biology & therapy 20080301
-
Pharmacological characterization of purified recombinant mTOR FRB-kinase domain using fluorescence-based assays.
Journal of biomolecular screening 20080301
-
[Rapamycin combined with donor bone marrow-derived immature dendritic cells induces mouse skin allograft tolerance].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080301
-
Therapeutic interventions for autosomal dominant polycystic kidney disease.
Nephrology news & issues 20080301
-
Rapamycin impairs beta-cell proliferation in vivo.
Transplantation proceedings 20080301
-
Influence of rapamycin on rat macrophage viability and chemotaxis toward allogenic pancreatic islet supernates.
Transplantation proceedings 20080301
-
Can we maintain immunosuppression avoiding nephrotoxic agents in pancreas transplantation?
Transplantation proceedings 20080301
-
Effects of drug-eluting stents on systemic inflammatory response in patients with unstable angina pectoris undergoing percutaneous coronary intervention.
Heart and vessels 20080301
-
Impact of sirolimus treatment in kidney allograft recipients with prolonged cold ischemia times: 5-year outcomes.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20080301
-
Fourteen month follow-up angioscopic findings of a sirolimus-eluting stent implanted in a 15-year-old saphenous vein graft.
International heart journal 20080301
-
Successful percutaneous treatment of an intraprocedural left main stent thrombosis with the support of an automatic mechanical chest compression device.
International journal of cardiology 20080227
-
Poor tolerance of sirolimus in a steroid avoidance regimen for renal transplantation.
Transplantation 20080227
-
Pericardial effusion coincident with sirolimus therapy: a review of Wyeth's safety database.
Transplantation 20080227
-
Safety and effectiveness of sirolimus-eluting stent implantation for in-stent restenosis of the unprotected left main coronary artery.
International journal of cardiology 20080220
-
Two-year clinical outcomes with drug-eluting stents for diabetic patients with de novo coronary lesions: results from a real-world multicenter registry.
Circulation 20080219
-
Safe use of raltegravir and sirolimus in an HIV-infected patient with renal impairment after orthotopic liver transplantation.
AIDS (London, England) 20080219
-
[Angiogenesis inhibitors for the systemic treatment of metastatic renal cell carcinoma: sunitinib, sorafenib, bevacizumab and temsirolimus].
Nederlands tijdschrift voor geneeskunde 20080216
-
Late target lesion revascularization after implantation of sirolimus-eluting stent.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080215
-
IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes.
Blood 20080215
-
A critical role for Lyn in acute myeloid leukemia.
Blood 20080215
-
A retroinhibition approach reveals a tumor cell-autonomous response to rapamycin in head and neck cancer.
Cancer research 20080215
-
Suppression of Peutz-Jeghers polyposis by targeting mammalian target of rapamycin signaling.
Clinical cancer research : an official journal of the American Association for Cancer Research 20080215
-
Comparison of a polymer-free rapamycin-eluting stent (YUKON) with a polymer-based paclitaxel-eluting stent (TAXUS) in real-world coronary artery lesions.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080215
-
Late target lesion revascularization following drug-eluting stents - looking back and forward to success.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080215
-
Drug for a while, polymer for life: Is it a good solution?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080215
-
Drug-eluting stenting of unprotected left main coronary artery stenosis in patients with orthotopic heart transplantation: Initial clinical experience.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080215
-
Prospective comparison of the use of sirolimus and cyclosporine in recipients of a kidney from an expanded criteria donor.
Transplantation 20080215
-
Prognostic value of the modified American College of Cardiology/American Heart Association lesion morphology classification for clinical outcome after sirolimus-eluting stent placement (results of the prospective multicenter German Cypher Registry).
The American journal of cardiology 20080215
-
Defective TGF-beta signaling sensitizes human cancer cells to rapamycin.
Oncogene 20080214
-
Regulation of cyclin D1 expression by mTORC1 signaling requires eukaryotic initiation factor 4E-binding protein 1.
Oncogene 20080214
-
Preparation of rapamycin-loaded chitosan/PLA nanoparticles for immunosuppression in corneal transplantation.
International journal of pharmaceutics 20080212
-
'Off-label' stent therapy 2-year comparison of drug-eluting versus bare-metal stents.
Journal of the American College of Cardiology 20080212
-
Sirolimus-eluting stents versus bare-metal stents in patients with ST-segment elevation myocardial infarction: 9-month angiographic and intravascular ultrasound results and 12-month clinical outcome results from the MISSION! Intervention Study.
Journal of the American College of Cardiology 20080212
-
Development of Kaposi's sarcoma under sirolimus-based immunosuppression and successful treatment with imiquimod.
Transplant infectious disease : an official journal of the Transplantation Society 20080201
-
Rhodococcus lung abscess complicating kidney transplantation: successful management by combination antibiotic therapy.
Transplant infectious disease : an official journal of the Transplantation Society 20080201
-
Rapamycin inhibits osteoblast proliferation and differentiation in MC3T3-E1 cells and primary mouse bone marrow stromal cells.
Journal of cellular biochemistry 20080201
-
Angiographic and 3D intravascular ultrasound assessment of overlapping bare metal stent and three different formulations of drug-eluting stents in patients with diabetes mellitus.
The international journal of cardiovascular imaging 20080201
-
Pulmonary lymphangioleiomyomatosis (LAM): progress and current challenges.
Journal of cellular biochemistry 20080201
-
Role of ICOS pathway in autoimmune and alloimmune responses in NOD mice.
Clinical immunology (Orlando, Fla.) 20080201
-
A randomized exploratory trial of steroid avoidance in renal transplant patients treated with everolimus and low-dose cyclosporine.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080201
-
Mechanical stimuli of skeletal muscle: implications on mTOR/p70s6k and protein synthesis.
European journal of applied physiology 20080201
-
Activation or inactivation of cardiac Akt/mTOR signaling diverges physiological from pathological hypertrophy.
Journal of cellular physiology 20080201
-
Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation.
Blood 20080201
-
Renal cortex neuronal nitric oxide synthase in response to rapamycin in kidney transplantation.
Nitric oxide : biology and chemistry 20080201
-
Amplification at 7q22 targets cyclin-dependent kinase 6 in T-cell lymphoma.
Leukemia 20080201
-
Induction of autophagy promotes fusion of multivesicular bodies with autophagic vacuoles in k562 cells.
Traffic (Copenhagen, Denmark) 20080201
-
Conversion to sirolimus for chronic allograft dysfunction: long-term results confirm predictive value of proteinuria.
Transplant international : official journal of the European Society for Organ Transplantation 20080201
-
Effect of calcineurin inhibitors on posaconazole blood levels as measured by the MVista microbiological assay.
Antimicrobial agents and chemotherapy 20080201
-
EMAP-II downregulation contributes to the beneficial effects of rapamycin after vascular injury.
Cardiovascular research 20080201
-
mTORC1 signaling can regulate growth factor activation of p44/42 mitogen-activated protein kinases through protein phosphatase 2A.
The Journal of biological chemistry 20080201
-
Sirolimus eluting stent (Cypher) in patients with diabetes mellitus: results from the German Cypher Stent Registry.
Clinical research in cardiology : official journal of the German Cardiac Society 20080201
-
Coronary in-stent restenosis in diabetic patients after implantation of sirolimus or paclitaxel drug-eluting coronary stents.
Diabetes & metabolism 20080201
-
Reduced positive affect (anhedonia) predicts major clinical events following implantation of coronary-artery stents.
Journal of internal medicine 20080201
-
The effects of sirolimus on wound healing in dermatologic surgery.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20080201
-
Low-dose mTOR inhibition by rapamycin attenuates progression in anti-thy1-induced chronic glomerulosclerosis of the rat.
American journal of physiology. Renal physiology 20080201
-
Rapamycin-conditioned, alloantigen-pulsed dendritic cells promote indefinite survival of vascularized skin allografts in association with T regulatory cell expansion.
Transplant immunology 20080201
-
The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model.
The Journal of clinical investigation 20080201
-
Three-dimensional compositional analysis of drug eluting stent coatings using cluster secondary ion mass spectrometry.
Analytical chemistry 20080201
-
Lentiviral vectors mediate nonimmunosuppressive rapamycin analog-induced production of secreted therapeutic factors in the brain: regulation at the level of transcription and exocytosis.
Human gene therapy 20080201
-
Transplantation: it may take two to tango and to treat.
Immunology and cell biology 20080201
-
Upregulation of tissue factor expression and thrombogenic activity in human aortic smooth muscle cells by irradiation, rapamycin and paclitaxel.
International immunopharmacology 20080201
-
Sicilian DES Registry: prospective in-hospital and 9-month clinical and angiographic follow-up in selected high restenosis risk patients.
Journal of cardiovascular medicine (Hagerstown, Md.) 20080201
-
Recurrent restenosis after implantation of sirolimus-eluting stents in aorto-ostial lesions: successful treatment with polytetrafluoroethylene-covered stents.
Journal of cardiovascular medicine (Hagerstown, Md.) 20080201
-
Sirolimus-based triple immunosupression with antithymocyte globulin induction in expanded criteria donor kidney transplantation.
Nephrology (Carlton, Vic.) 20080201
-
Antiproliferative and proapoptotic effects of rapamycin and celecoxib in malignant melanoma cell lines.
Oncology reports 20080201
-
Sirolimus associated pneumonitis after nonmyeloablative peripheral blood stem cell transplant for sickle cell disease.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080201
-
Incidence of premature discontinuation of antiplatelet therapy after sirolimus-eluting stent implantation.
Circulation journal : official journal of the Japanese Circulation Society 20080201
-
Everolimus exposure in cardiac transplant recipients is influenced by concomitant calcineurin inhibitor.
Therapeutic drug monitoring 20080201
-
Inhibition of the mammalian target of rapamycin (mTOR) in a case of refractory primary cutaneous anaplastic large cell lymphoma.
Leukemia & lymphoma 20080201
-
Effects of rapamycin in liver transplantation.
Hepatobiliary & pancreatic diseases international : HBPD INT 20080201
-
Increased expression of the glioma-associated antigen ARF4L after loss of the tumor suppressor PTEN. Laboratory investigation.
Journal of neurosurgery 20080201
-
Antiangiogenic therapy with mammalian target of rapamycin inhibitor RAD001 (Everolimus) increases radiosensitivity in solid cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 20080201
-
Lymphangioleiomyomatosis: a clinical update.
Chest 20080201
-
Pulmonary complications of novel antineoplastic agents for solid tumors.
Chest 20080201
-
Multidisciplinary insights on clinical guidance for the use of proliferation signal inhibitors in heart transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080201
-
Cyclosporine reduction in the presence of everolimus: 3-month data from a Canadian pilot study of maintenance cardiac allograft recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080201
-
Expression of signaling mediators downstream of EGF-receptor predict sensitivity to small molecule inhibitors directed against the EGF-receptor pathway.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080201
-
The potential role of mTOR inhibitors in non-small cell lung cancer.
The oncologist 20080201
-
Effects of the mTOR inhibitor sirolimus in patients with hepatocellular and cholangiocellular cancer.
International journal of clinical oncology 20080201
-
Drug-eluting stents: a review of current evidence on clinical effectiveness and late complications.
Scottish medical journal 20080201
-
Towards defining the role of drug eluting stents.
Minerva cardioangiologica 20080201
-
Sirolimus, Tacrolimus and Zotarolimus eluting stents to treat bifurcated lesions: a 7-month clinical outcome comparison.
Minerva cardioangiologica 20080201
-
Percutaneous coronary intervention with everolimus-eluting stents (Xience V): systematic review and direct-indirect comparison meta-analyses with paclitaxel-eluting stents (Taxus) and sirolimus-eluting stents (Cypher).
Minerva cardioangiologica 20080201
-
Future stent drug delivery systems.
Minerva cardioangiologica 20080201
-
Primary and mid-term outcome of sirolimus-eluting stent implantation with angiographic guidance alone.
Journal of cardiology 20080201
-
Medial necrosis due to sirolimus-eluting stent implantation in human coronary artery.
Journal of cardiology 20080201
-
Late giant coronary aneurysm associated with a fracture of sirolimus eluting stent: a case report.
Journal of cardiology 20080201
-
Next-generation drug-eluting stents in coronary artery disease: focus on everolimus-eluting stent (Xience V).
Vascular health and risk management 20080201
-
Advances in immunosuppression for pancreas transplantation.
Current opinion in organ transplantation 20080201
-
[Long-term efficacy of sirolimus-eluting stents (Cypher) versus bare metal stents for patients with ST-segment elevation myocardial infarction].
Zhonghua xin xue guan bing za zhi 20080201
-
[Effects of mTOR inhibitor rapamycin on Smad 3 protein and collagen type I expression in rat myocardial fibroblasts infected with coxsackie virus B 3].
Zhonghua xin xue guan bing za zhi 20080201
-
Six-month comparison of coronary endothelial dysfunction associated with sirolimus-eluting stent versus Paclitaxel-eluting stent.
JACC. Cardiovascular interventions 20080201
-
Comparison of paclitaxel- and sirolimus-eluting stents in everyday clinical practice: the SORT OUT II randomized trial.
JAMA 20080130
-
Effectiveness of drug-eluting stents in real-world patients.
JAMA 20080130
-
Long-term survival of limb allografts induced by pharmacologically conditioned, donor alloantigen-pulsed dendritic cells without maintenance immunosuppression.
Transplantation 20080127
-
Comparison of sirolimus alone with sirolimus plus tacrolimus in type 1 diabetic recipients of cultured islet cell grafts.
Transplantation 20080127
-
Sympathetic dystrophy associated with sirolimus therapy.
Transplantation 20080127
-
Angioplasty for the late stent thrombosis, the new technical challenge: a single centre experience.
International journal of cardiology 20080124
-
Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR.
Oncogene 20080124
-
Concerns in the SESAMI trial.
Journal of the American College of Cardiology 20080122
-
mTOR: the mammalian target of replication.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080120
-
Phase I trial of the novel mammalian target of rapamycin inhibitor deforolimus (AP23573; MK-8669) administered intravenously daily for 5 days every 2 weeks to patients with advanced malignancies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080120
-
Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys.
Journal of the National Cancer Institute 20080116
-
Surface immobilization of chondroitin 6-sulfate/heparin multilayer on stainless steel for developing drug-eluting coronary stents.
Colloids and surfaces. B, Biointerfaces 20080115
-
A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin.
Human molecular genetics 20080115
-
Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival.
Blood 20080115
-
Rapamycin inhibits PAI-1 expression and reduces interstitial fibrosis and glomerulosclerosis in chronic allograft nephropathy.
Transplantation 20080115
-
Rapamycin, but not cyclosporine or FK506, alters natural killer cell function.
Transplantation 20080115
-
Mammalian target of rapamycin is the key effector of phosphatidylinositol-3-OH-initiated proliferative signals in the thyroid follicular epithelium.
Cancer research 20080115
-
Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway.
The Journal of biological chemistry 20080111
-
Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis.
The New England journal of medicine 20080110
-
Efficacy of sirolimus in treating tuberous sclerosis and lymphangioleiomyomatosis.
The New England journal of medicine 20080110
-
Sirolimus therapy in tuberous sclerosis or sporadic lymphangioleiomyomatosis.
The New England journal of medicine 20080110
-
TORC1 is essential for NF1-associated malignancies.
Current biology : CB 20080108
-
Effects of sirolimus-eluting stent on calcified coronary lesions.
Chinese medical journal 20080105
-
Coupling of mammalian target of rapamycin with phosphoinositide 3-kinase signaling pathway regulates protein phosphatase 2A- and glycogen synthase kinase-3 -dependent phosphorylation of Tau.
The Journal of biological chemistry 20080104
-
Refeeding and insulin activate the AKT/p70S6 kinase pathway without affecting IRS1 tyrosine phosphorylation in chicken muscle.
Domestic animal endocrinology 20080101
-
Pharmacometrics and delivery of novel nanoformulated PEG-b-poly(epsilon-caprolactone) micelles of rapamycin.
Cancer chemotherapy and pharmacology 20080101
-
Can mTOR inhibitors reduce the risk of late kidney allograft failure?
Transplant international : official journal of the European Society for Organ Transplantation 20080101
-
Plasticity of ovarian cancer cell SKOV3ip and vasculogenic mimicry in vivo.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20080101
-
Are impaired endothelial progenitor cells involved in the processes of late in-stent thrombosis and re-endothelialization of drug-eluting stents?
Medical hypotheses 20080101
-
Mammalian target of rapamycin (mTOR) inhibition activates phosphatidylinositol 3-kinase/Akt by up-regulating insulin-like growth factor-1 receptor signaling in acute myeloid leukemia: rationale for therapeutic inhibition of both pathways.
Blood 20080101
-
Adjuvant conversion to sirolimus in liver transplant patients with recurrent hepatocellular carcinoma - preliminary results.
Transplant international : official journal of the European Society for Organ Transplantation 20080101
-
The role of cell signaling in poxvirus tropism: the case of the M-T5 host range protein of myxoma virus.
Biochimica et biophysica acta 20080101
-
Head-to-head comparison of sirolimus- and paclitaxel-eluting stent in the same diabetic patient with multiple coronary artery lesions: a prospective, randomized, multicenter study.
Diabetes care 20080101
-
Role of mTOR in physiology and pathology of the nervous system.
Biochimica et biophysica acta 20080101
-
Association study of ABCB1 and CYP3A5 gene polymorphisms with sirolimus trough concentration and dose requirements in Chinese renal transplant recipients.
Biopharmaceutics & drug disposition 20080101
-
Translational activation of 5'-TOP mRNA in pressure overload myocardium.
Basic research in cardiology 20080101
-
Neointimal expression of rapamycin receptor FK506-binding protein FKBP12: postinjury animal and human in-stent restenosis tissue characteristics.
Journal of vascular research 20080101
-
Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells.
Blood 20080101
-
Simultaneous hybrid coronary revascularization using totally endoscopic left internal mammary artery bypass grafting and placement of rapamycin eluting stents in the same interventional session. The COMBINATION pilot study.
Cardiology 20080101
-
Myxoma virus oncolysis of primary and metastatic B16F10 mouse tumors in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 20080101
-
Octreotide and the mTOR inhibitor RAD001 (everolimus) block proliferation and interact with the Akt-mTOR-p70S6K pathway in a neuro-endocrine tumour cell Line.
Neuroendocrinology 20080101
-
The oral mTOR inhibitor RAD001 (everolimus) in combination with letrozole in patients with advanced breast cancer: results of a phase I study with pharmacokinetics.
European journal of cancer (Oxford, England : 1990) 20080101
-
Novel methods for tracking long-term maintenance immunosuppression regimens.
Clinical journal of the American Society of Nephrology : CJASN 20080101
-
Comparison of vascular response to zotarolimus-eluting stent versus sirolimus-eluting stent: intravascular ultrasound results from ENDEAVOR III.
American heart journal 20080101
-
Insulin and IGF-1 enhance the expression of the neuronal monocarboxylate transporter MCT2 by translational activation via stimulation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin pathway.
The European journal of neuroscience 20080101
-
Restenosis of the CYPHER-Select, TAXUS-Express, and Polyzene-F nanocoated cobalt-chromium stents in the minipig coronary artery model.
Cardiovascular and interventional radiology 20080101
-
Ex vivo rapamycin generates apoptosis-resistant donor Th2 cells that persist in vivo and prevent hemopoietic stem cell graft rejection.
Journal of immunology (Baltimore, Md. : 1950) 20080101
-
Huge right atrial thrombus 6 years after heart transplantation.
The Annals of thoracic surgery 20080101
-
Clinical outcomes after heterogeneous overlap stenting with drug-eluting stents and bare-metal stents for de novo coronary artery narrowings.
The American journal of cardiology 20080101
-
Short- and long-term outcomes after stent-assisted percutaneous treatment of saphenous vein grafts in the drug-eluting stent era.
The American journal of cardiology 20080101
-
Results of percutaneous coronary intervention of the unprotected left main coronary artery in 143 patients and comparison of 30-day mortality to results of coronary artery bypass grafting.
The American journal of cardiology 20080101
-
Sirolimus-eluting stents vs bare metal stents for coronary intervention in Japanese patients with renal failure on hemodialysis.
Circulation journal : official journal of the Japanese Circulation Society 20080101
-
Late stent thrombosis in patients receiving ticlopidine and aspirin after sirolimus-eluting stent implantation.
Circulation journal : official journal of the Japanese Circulation Society 20080101
-
Evaluation of antileukaemic effects of rapamycin in patients with imatinib-resistant chronic myeloid leukaemia.
European journal of clinical investigation 20080101
-
Changes in CCR2 chemokine receptor expression and plasma MCP-1 concentration after the implantation of bare metal stents versus sirolimus-eluting stents in patients with stable angina.
Internal medicine (Tokyo, Japan) 20080101
-
Sirolimus-induced inflammatory papules with acquired reactive perforating collagenosis.
Dermatology (Basel, Switzerland) 20080101
-
San Antonio Breast Cancer Symposium.
The Lancet. Oncology 20080101
-
Impact of lesion calcification on clinical and angiographic outcome after sirolimus-eluting stent implantation in real-world patients.
Cardiovascular revascularization medicine : including molecular interventions 20080101
-
Drug-eluting stents are associated with similar cardiovascular outcomes when compared to bare metal stents in the setting of acute myocardial infarction.
Cardiovascular revascularization medicine : including molecular interventions 20080101
-
Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma.
PLoS medicine 20080101
-
Incorporating molecular tools into early-stage clinical trials.
PLoS medicine 20080101
-
Calcineurin inhibitor-sparing regimens in solid organ transplantation: focus on improving renal function and nephrotoxicity.
Clinical transplantation 20080101
-
A sensitive high-throughput HPLC assay for simultaneous determination of everolimus and clobetasol propionate.
Journal of chromatographic science 20080101
-
Can the wound healing response of human skin be modulated after laser treatment and the effects of exposure extended? Implications on the combined use of the pulsed dye laser and a topical angiogenesis inhibitor for treatment of port wine stain birthmarks.
Lasers in surgery and medicine 20080101
-
Tuberous sclerosis: a primary pathology of astrocytes?
Epilepsia 20080101
-
Topical rapamycin inhibits tuberous sclerosis tumor growth in a nude mouse model.
BMC dermatology 20080101
-
[Molecular targeted therapy for renal cell carcinoma].
Hinyokika kiyo. Acta urologica Japonica 20080101
-
The effect of sirolimus in the development of chronic allograft nephropathy.
Transplantation proceedings 20080101
-
The mTOR inhibitor everolimus attenuates the time course of chronic anti-Thy1 nephritis in the rat.
Nephron. Experimental nephrology 20080101
-
Hsf1 activation inhibits rapamycin resistance and TOR signaling in yeast revealed by combined proteomic and genetic analysis.
PloS one 20080101
-
Comparison of long-term angiographic follow-up after sirolimus-eluting stent and bare-metal stent implantation.
Internal medicine (Tokyo, Japan) 20080101
-
Obesity following kidney transplantation and steroid avoidance immunosuppression.
Clinical transplantation 20080101
-
Early, abrupt conversion of de novo renal transplant patients from cyclosporine to everolimus: results of a pilot study.
Clinical transplantation 20080101
-
mTOR inhibitors and calcineurin inhibitors do not affect adhesion molecule expression of human macro- and microvascular endothelial cells.
Journal of vascular research 20080101
-
SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts.
PloS one 20080101
-
Mycophenolate mofetil vs. sirolimus in kidney transplant recipients receiving tacrolimus-based immunosuppressive regimen.
Clinical transplantation 20080101
-
Use of low dose tacrolimus, mycophenolate mofetil and maintenance IL-2 receptor blockade in an islet transplant recipient.
Clinical transplantation 20080101
-
Generalized lymphedema in a sirolimus-treated renal transplant patient.
Clinical transplantation 20080101
-
The combination of sirolimus and cyclosporine does not delay initial renal graft function recovery.
Renal failure 20080101
-
[Rapamycin and lymphangiogenesis: side effect or treatment result?].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20080101
-
Solution structure of the Legionella pneumophila Mip-rapamycin complex.
BMC structural biology 20080101
-
Pathobiology and prognosis of chromophobe renal cell carcinoma.
Urologic oncology 20080101
-
Temsirolimus: in advanced renal cell carcinoma.
Drugs 20080101
-
The PI-3kinase pathway in hematopoietic stem cells and leukemia-initiating cells: a mechanistic difference between normal and cancer stem cells.
Blood cells, molecules & diseases 20080101
-
Crush stenting with paclitaxel-eluting or sirolimus-eluting stents for the treatment of coronary bifurcation lesions.
Angiology 20080101
-
Characterization of the Rheb-mTOR signaling pathway in mammalian cells: constitutive active mutants of Rheb and mTOR.
Methods in enzymology 20080101
-
Total synthesis studies on macrocyclic pipecolic acid natural products: FK506, the antascomicins and rapamycin.
Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques 20080101
-
Drug-eluting stents - what should be improved?
Annals of medicine 20080101
-
Persistent peritoneal dialysis catheter exit-site leak in a patient receiving maintenance immunosuppression with sirolimus.
Clinical transplantation 20080101
-
The evolution of immunosuppressant therapy in renal transplantation.
Drugs 20080101
-
Malignancy in kidney transplant recipients.
Drugs 20080101
-
Mechanisms and management of proteinuria in kidney transplant patients.
Drugs 20080101
-
Sirolimus use in recipients of expanded criteria donor kidneys.
Drugs 20080101
-
Better understanding of ADPKD results in potential new treatment options: ready for the cure?
Journal of nephrology 20080101
-
Comparison of bare-metal and sirolimus- or paclitaxel-eluting stents for aorto-ostial coronary disease.
Cardiology 20080101
-
A preliminary experience report: Drug-eluting stents versus coronary artery bypass surgery in patients with a single lesion in the proximal left anterior descending artery suffering from diabetes mellitus and chronic stable angina.
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20080101
-
The mTOR signaling network: insights from its role during embryonic development.
Current medicinal chemistry 20080101
-
Pharmacokinetics of mycophenolic acid, tacrolimus and sirolimus after gastric bypass surgery in end-stage renal disease and transplant patients: a pilot study.
Clinical transplantation 20080101
-
Neovascular age-related macular degeneration: potential therapies.
Drugs 20080101
-
Successful treatment of a coronary cameral fistula secondary to elective sirolimus-eluting stent implantation.
Cardiovascular revascularization medicine : including molecular interventions 20080101
-
Efficacy and safety of drug-eluting stents in long-term follow-up.
Internal medicine (Tokyo, Japan) 20080101
-
Stability of sirolimus and everolimus measured by immunoassay techniques in whole blood samples from kidney transplant patients.
International journal of immunopathology and pharmacology 20080101
-
Activation of the mammalian target of rapamycin complex 1 is both necessary and sufficient to stimulate eukaryotic initiation factor 2Bvarepsilon mRNA translation and protein synthesis.
The international journal of biochemistry & cell biology 20080101
-
Resistance exercise biology: manipulation of resistance exercise programme variables determines the responses of cellular and molecular signalling pathways.
Sports medicine (Auckland, N.Z.) 20080101
-
Sirolimus induced dyslipidemia in tacrolimus based vs. tacrolimus free immunosuppressive regimens in renal transplant recipients.
Annals of transplantation 20080101
-
Meta-analysis shows similar risk of thrombosis after drug-eluting stent, bare-metal stent, or angioplasty.
Endothelium : journal of endothelial cell research 20080101
-
Rapamycin delays growth of Wnt-1 tumors in spite of suppression of host immunity.
BMC cancer 20080101
-
On the action of cyclosporine A, rapamycin and tacrolimus on M. avium including subspecies paratuberculosis.
PloS one 20080101
-
Effect of rifampicin to inhibit rapamycin-induced autophagy via the suppression of protein phosphatase 2A activity.
Immunopharmacology and immunotoxicology 20080101
-
An update on the medical therapy of advanced metastatic renal cell carcinoma.
Scandinavian journal of urology and nephrology 20080101
-
Comparison between a liquid chromatography-tandem mass spectrometry assay and a fluorescent polarization immunoassay to measure whole blood everolimus concentration in heart and renal transplantations.
Journal of clinical laboratory analysis 20080101
-
IGF-I receptor inhibition combined with rapamycin or temsirolimus inhibits neuroblastoma cell growth.
Anticancer research 20080101
-
Nonimmunosuppressive effects of mammalian target of rapamycin inhibitors.
Transplantation reviews (Orlando, Fla.) 20080101
-
Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer.
BMC genomics 20080101
-
Negative inotropic effect of rapamycin on isolated human cardiomyocytes.
The Journal of international medical research 20080101
-
Mammalian target of rapamycin as a target in hematological malignancies.
Current problems in cancer 20080101
-
Selective corticosteroid and calcineurin-inhibitor withdrawal after pancreas-kidney transplantation utilizing thymoglobulin induction and sirolimus maintenance therapy.
Clinical transplantation 20080101
-
[To stay immature: the first step to tolerate?].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20080101
-
Effects of everolimus monotherapy on hematological parameters and iron homeostasis in de novo liver transplant recipients: preliminary results.
Transplantation proceedings 20080101
-
Sirolimus therapy in liver transplant patients: an initial experience at a single center.
Transplantation proceedings 20080101
-
[Role of PTEN protein in multidrug resistance of prostate cancer cells].
Molekuliarnaia biologiia 20080101
-
Current management of tuberous sclerosis complex.
Paediatric drugs 20080101
-
TOR signaling in fission yeast.
Critical reviews in biochemistry and molecular biology 20080101
-
Drug eluting and bare metal stents in people with and without diabetes: collaborative network meta-analysis.
BMJ (Clinical research ed.) 20080101
-
The South African branch of the Crossroads Institute celebrates it second birthday.
Cardiovascular journal of Africa 20080101
-
[Tirofiban or abciximab and sirolimus-eluting or bare metal uncoated stents in primary percutaneous coronary intervention for acute myocardial infarction: results of MULTISTRATEGY trial].
Kardiologiia 20080101
-
Clinical results of drug eluting stents compared to bare metal stents for patients with ST elevation acute myocardial infarction.
Acute cardiac care 20080101
-
Influence of interactions between immunosuppressive drugs on therapeutic drug monitoring.
Annals of transplantation 20080101
-
Orally administered rapamycin, dacarbazine or both for treatment of human melanoma evaluated in severe combined immunodeficiency mice.
Pharmacology 20080101
-
Monotherapy with anti-LFA-1 monoclonal antibody promotes long-term survival of rat islet xenografts.
Cell transplantation 20080101
-
Quantification of sirolimus and everolimus by immunoassay techniques: test specificity and cross-reactivity evaluation.
International journal of immunopathology and pharmacology 20080101
-
Signaling inhibitors in metastatic renal cell carcinoma.
Cancer journal (Sudbury, Mass.) 20080101
-
From Easter Island to coated coronary stents: a remarkable saga.
Journal of the Medical Association of Georgia 20080101
-
A rapid liquid chromatography-tandem mass spectrometry analysis of whole blood sirolimus using turbulent flow technology for online extraction.
Clinical chemistry and laboratory medicine 20080101
-
TOR regulates cell death induced by telomere dysfunction in budding yeast.
PloS one 20080101
-
Efficacy of rapamycin in scleroderma: a case study.
Lymphatic research and biology 20080101
-
Effects of everolimus as an antiproliferative agent on regression of encapsulating peritoneal sclerosis in a rat model.
Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20080101
-
Failure of systematic error detection with internal quality control program.
Annals of clinical and laboratory science 20080101
-
[Chronic allograft dysfunction: role of immunosuppressive treatment].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20080101
-
Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability.
Molecular cancer 20080101
-
[ASCO 2008. Bevacizumab in advanced renal carcinoma].
Tumori 20080101
-
PTEN and rapamycin inhibiting the growth of K562 cells through regulating mTOR signaling pathway.
Journal of experimental & clinical cancer research : CR 20080101
-
Effect of intestinal and hepatic first-pass extraction on the pharmacokinetics of everolimus in rats.
Drug metabolism and pharmacokinetics 20080101
-
[Experience with primary coronary angioplasty in management of patients suffering from acute myocardial infarction].
Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20080101
-
[Problem of restenosis inside stents with an antiproliferative coating].
Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20080101
-
Methods to investigate autophagy during starvation and regeneration in hydra.
Methods in enzymology 20080101
-
mTOR inhibition sensitizes gastric cancer to alkylating chemotherapy in vivo.
Anticancer research 20080101
-
A case of complete revascularization with nine sirolimus eluting stents.
Indian heart journal 20080101
-
Sirolimus-loaded polyurethane graft for hemodialysis access in sheep.
Vascular 20080101
-
Two-year (mid-term) results for unprotected left main coronary artery percutaneous interventions with drug-eluting stents.
Indian heart journal 20080101
-
Preclinical and early clinical experience with a biodegradable polymer-based, rapamycin-eluting, Indian drug-eluting coronary stent: the BIO-RAPID study.
Indian heart journal 20080101
-
[Experience in using stents with an antiproliferative coating in treatment of stenoses and occlusions of coronary arteries. Review of the literature].
Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20080101
-
Chemically induced and light-independent cryptochrome photoreceptor activation.
Molecular plant 20080101
-
Rapamycin impairs in vivo proliferation of islet beta-cells.
Transplantation 20071227
-
Long-term limb allograft survival using a short course of anti-CD45RB monoclonal antibody, LF 15-0195, and rapamycin in a mouse model.
Transplantation 20071227
-
Apoptosis and autophagy as mechanisms of dinoflagellate symbiont release during cnidarian bleaching: every which way you lose.
Proceedings. Biological sciences 20071222
-
Targeted drugs for metastatic renal cell carcinoma.
Lancet (London, England) 20071222
-
Safety of drug-eluting stents: demystifying network meta-analysis.
Lancet (London, England) 20071222
-
The pancreatitis-induced vacuole membrane protein 1 triggers autophagy in mammalian cells.
The Journal of biological chemistry 20071221
-
Reduced exposure to calcineurin inhibitors in renal transplantation.
The New England journal of medicine 20071220
-
Balancing efficacy and toxicity in kidney-transplant immunosuppression.
The New England journal of medicine 20071220
-
Advancing the knowledge base on the efficacy-safety ratio with drug-eluting stents contributions from the European Society of Cardiology Congress, Vienna, Austria, September 1-5, 2007.
Journal of the American College of Cardiology 20071218
-
Temsirolimus (Torisel) for advanced renal cell carcinoma.
The Medical letter on drugs and therapeutics 20071217
-
Angiographic and intravascular ultrasound study of the effects of overlapping sirolimus- and paclitaxel-eluting stents: comparison with same drug-eluting overlapping stents.
International journal of cardiology 20071215
-
Comparison of bypass surgery with drug-eluting stents for diabetic patients with multivessel disease.
International journal of cardiology 20071215
-
Determination of the rate constants for the FK506 binding protein/rapamycin interaction using surface plasmon resonance: an alternative sensor surface for Ni2+-nitrilotriacetic acid immobilization of His-tagged proteins.
Analytical biochemistry 20071215
-
The selectivity of protein kinase inhibitors: a further update.
The Biochemical journal 20071215
-
Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells.
International immunopharmacology 20071215
-
A lower incidence of cytomegalovirus infection in de novo heart transplant recipients randomized to everolimus.
Transplantation 20071215
-
The mTOR inhibitor everolimus induces proteinuria and renal deterioration in the remnant kidney model in the rat.
Transplantation 20071215
-
Pharmacokinetic and tumor distribution characteristics of temsirolimus in patients with recurrent malignant glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20071215
-
Rapamycin promotes vascular smooth muscle cell differentiation through insulin receptor substrate-1/phosphatidylinositol 3-kinase/Akt2 feedback signaling.
The Journal of biological chemistry 20071207
-
Minor contribution of an internal ribosome entry site in the 5'-UTR of ornithine decarboxylase mRNA on its translation.
Biochemical and biophysical research communications 20071207
-
Sirolimus-induced drug fever and ciclosporin-induced leukencephalopathia with seizures in one liver transplant recipient.
World journal of gastroenterology 20071207
-
Conversion to sirolimus as primary immunosuppression attenuates the progression of allograft vasculopathy after cardiac transplantation.
Circulation 20071204
-
Sirolimus and cardiac transplantation: is it the 'magic bullet'?
Circulation 20071204
-
Decreased levels of hypoxic cells in gefitinib treated ER+ HER-2 overexpressing MCF-7 breast cancer tumors are associated with hyperactivation of the mTOR pathway: therapeutic implications for combination therapy with rapamycin.
Breast cancer research and treatment 20071201
-
Pharmacokinetics, safety, and efficacy of mycophenolate mofetil in combination with sirolimus or ciclosporin in renal transplant patients.
British journal of clinical pharmacology 20071201
-
Sirolimus (rapamycin): from the soil of Easter Island to a bright future.
Journal of the American Academy of Dermatology 20071201
-
Pneumonitis associated with sirolimus: clinical characteristics, risk factors and outcome--a single-centre experience and review of the literature.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20071201
-
Efficacy of reduced-dose sirolimus-eluting stents in the human coronary artery: serial IVUS analysis of neointimal hyperplasia and luminal dimension.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071201
-
Long-term clinical follow-up of sirolimus-eluting (CYPHER) coronary stents in the treatment of instent restenosis in an unselected population.
Heart, lung & circulation 20071201
-
Functional and phenotypic characteristics of CD4+CD25highFoxp3+ Treg clones obtained from peripheral blood of patients with cancer.
International journal of cancer 20071201
-
Proteinuria after kidney transplantation, relationship to allograft histology and survival.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20071201
-
Clinically relevant immunosuppressants influence UVB-induced tumor size through effects on inflammation and angiogenesis.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20071201
-
Immunosuppressant pharmacokinetics and dosing modifications in HIV-1 infected liver and kidney transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20071201
-
Genetically encoded molecules for inducibly inactivating CaV channels.
Nature chemical biology 20071201
-
Effects of rapamycin on gene expression, morphology, and electrophysiological properties of rat hippocampal neurons.
Epilepsy research 20071201
-
Immunosuppressive agents: effects on glucose and lipid metabolism.
Endocrinology and metabolism clinics of North America 20071201
-
Regulation of elongation phase of mRNA translation in diabetic nephropathy: amelioration by rapamycin.
The American journal of pathology 20071201
-
Serial long-term evaluation of neointimal stent coverage and thrombus after sirolimus-eluting stent implantation by use of coronary angioscopy.
Heart (British Cardiac Society) 20071201
-
Strut fracture of a sirolimus-eluting stent at the ostium of the right coronary artery.
Heart (British Cardiac Society) 20071201
-
Impact of metabolic syndrome on clinical and angiographic outcome after sirolimus-eluting stent implantation.
Coronary artery disease 20071201
-
RESTEM: a percutaneous coronary intervention 'real world' registry in the drug-eluting stent era.
Coronary artery disease 20071201
-
Chemical genetic modification of Ca2+ channel activity.
Nature chemical biology 20071201
-
Cost-effectiveness of sirolimus-eluting stents compared with vascular brachytherapy for the treatment of in-stent restenosis.
American heart journal 20071201
-
Comparison of effects of telmisartan and valsartan on late lumen loss and inflammatory markers after sirolimus-eluting stent implantation in hypertensive patients.
The American journal of cardiology 20071201
-
Long-term clinical benefit of sirolimus-eluting stents compared to bare metal stents in the treatment of saphenous vein graft disease.
Journal of interventional cardiology 20071201
-
Crossreactivity of isolated everolimus metabolites with the Innofluor Certican immunoassay for therapeutic drug monitoring of everolimus.
Therapeutic drug monitoring 20071201
-
A randomized controlled trial of late conversion from calcineurin inhibitor (CNI)-based to sirolimus-based immunosuppression in liver transplant recipients with impaired renal function.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20071201
-
Analysis of bifurcation lesions treated with novel drug-eluting dedicated bifurcation stent system: intravascular ultrasound results of the AXXESS PLUS trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071201
-
Percutaneous coronary intervention in the 21st century - making surgeons irrelevant?
Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine 20071201
-
Targeting protein translation in human non small cell lung cancer via combined MEK and mammalian target of rapamycin suppression.
Cancer research 20071201
-
Pravastatin induces rat aortic endothelial cell proliferation and migration via activation of PI3K/Akt/mTOR/p70 S6 kinase signaling.
Journal of pharmacological sciences 20071201
-
Small-molecule and antibody approaches to molecular chemotherapy of primary brain tumors.
Current opinion in investigational drugs (London, England : 2000) 20071201
-
Sirolimus-eluting versus bare-metal stents for the reduction of coronary restenosis: 18-month angiographic results from the GERSHWIN Study.
Herz 20071201
-
Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits.
Genes to cells : devoted to molecular & cellular mechanisms 20071201
-
[mTOR signal pathway and its inhibitors in antitumor therapy: a review].
Ai zheng = Aizheng = Chinese journal of cancer 20071201
-
[Rapamycin affects eIF- 4E expression in rat myocardial fibroblasts infected by Coxsackievirus B3].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20071201
-
Proliferation signal inhibitors in transplantation: questions at the cutting edge of everolimus therapy.
Transplantation proceedings 20071201
-
Statins benefit outcomes of renal transplant recipients on a sirolimus-cyclosporine regimen.
Transplantation proceedings 20071201
-
Posttransplantation conversion to sirolimus-based immunosuppression: a single center experience.
Transplantation proceedings 20071201
-
Economic evaluation of everolimus and mycophenolate mofetil versus azathioprine in de novo heart transplantation.
Transplantation proceedings 20071201
-
Anti-CD25 mAb, anti-IL2 mAb, and IL2 block tolerance induction through anti-CD154 mAb and rapamycin in xenogeneic islet transplantation.
Transplantation proceedings 20071201
-
An unusual presentation of sirolimus associated cough in a renal transplant recipient.
Transplantation proceedings 20071201
-
Interstitial pneumonitis associated with sirolimus in liver transplantation: a case report.
Transplantation proceedings 20071201
-
Switch to everolimus for sirolimus-induced pneumonitis in a liver transplant recipient--not all proliferation signal inhibitors are the same: a case report.
Transplantation proceedings 20071201
-
[Therapeutic effect of sirolimus against chronic allograft nephropathy in kidney transplant recipients].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20071201
-
Acute thrombosis of a mesenteric artery drug-eluting stent following clopidogrel cessation.
Vascular and endovascular surgery 20071201
-
Characterization of late incomplete stent apposition: a comparison among bare-metal stents, intracoronary radiation and sirolimus-eluting stents.
The Journal of invasive cardiology 20071201
-
The Cairo kidney center protocol for rapamycin-based sequential immunosuppression in kidney transplant recipients: 2-year outcomes.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20071201
-
New strategies for the treatment of metastatic bone disease.
Clinical breast cancer 20071201
-
[Synergistic effect of rapamycin (RPM) and PD98059 on cell cycle and mTOR signal transduction in human colorectal cancer cells].
Zhonghua zhong liu za zhi [Chinese journal of oncology] 20071201
-
Clinically significant proteinuria following the administration of sirolimus to renal transplant recipients.
Drug metabolism letters 20071201
-
mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.
Nature 20071129
-
Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53.
The EMBO journal 20071128
-
Gender-specific outcomes after sirolimus-eluting stent implantation.
Journal of the American College of Cardiology 20071127
-
Peeling-off labels mounting evidence for benefit of drug-eluting stents with off-label use.
Journal of the American College of Cardiology 20071120
-
Sirolimus-eluting stent treatment as buffer for inflamed lesions identified by serum marker estimation. The STABILISE pilot study.
International journal of cardiology 20071115
-
Steroid-free maintenance immunosuppression with rapamune and low-dose neoral in pancreas transplant recipients.
Transplantation 20071115
-
Drug eluting stents versus coronary artery bypass surgery in patients with isolated proximal lesion in left anterior descending artery suffering from chronic stable angina.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071115
-
Cell signaling. mTOR, unleashed.
Science (New York, N.Y.) 20071109
-
Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38.
Science (New York, N.Y.) 20071109
-
Intravascular drug release kinetics dictate arterial drug deposition, retention, and distribution.
Journal of controlled release : official journal of the Controlled Release Society 20071106
-
Cost-effectiveness of drug-eluting stents in patients at high or low risk of major cardiac events in the Basel Stent KostenEffektivitäts Trial (BASKET): an 18-month analysis.
Lancet (London, England) 20071103
-
Sirolimus blocks the accumulation of hyaluronan (HA) by arterial smooth muscle cells and reduces monocyte adhesion to the ECM.
Atherosclerosis 20071101
-
Preparation and characterization of rapamycin-loaded PLGA coating stent.
Journal of materials science. Materials in medicine 20071101
-
Blockade of chronic graft-versus-host disease by alloantigen-induced CD4+CD25+Foxp3+ regulatory T cells in nonlymphopenic hosts.
Journal of leukocyte biology 20071101
-
A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase.
Cell death and differentiation 20071101
-
Everolimus-associated interstitial pneumonitis in a patient with a heart transplant.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20071101
-
Sirolimus versus cyclosporine in kidney recipients receiving thymoglobulin, mycophenolate mofetil and a 6-month course of steroids.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20071101
-
Molecular targeted therapy of head and neck cancer: review and clinical development challenges.
European journal of cancer (Oxford, England : 1990) 20071101
-
Sirolimus in chronic allograft nephropathy in pediatric recipients.
Pediatric transplantation 20071101
-
Pharmacokinetic profile of temsirolimus with concomitant administration of cytochrome p450-inducing medications.
Journal of clinical pharmacology 20071101
-
Randomized trial of rapamycin- and paclitaxel-eluting stents with identical biodegradable polymeric coating and design.
European heart journal 20071101
-
RyR1-specific requirement for depolarization-induced Ca2+ sparks in urinary bladder smooth muscle.
Journal of cell science 20071101
-
Implantation of sirolimus-eluting stents in saphenous vein grafts is associated with high clinical follow-up event rates compared with treatment of native vessels.
Coronary artery disease 20071101
-
Serial long-term evaluation of neointimal stent coverage and thrombus after sirolimus-eluting stent implantation by use of coronary angioscopy.
Heart (British Cardiac Society) 20071101
-
Distinctive expression and functional regulation of the maize (Zea mays L.) TOR kinase ortholog.
Molecular bioSystems 20071101
-
Impact of the metabolic syndrome on angiographic and clinical events after coronary intervention using bare-metal or sirolimus-eluting stents.
The American journal of cardiology 20071101
-
Post-renal transplant hemolytic uremic syndrome following combination therapy with tacrolimus and everolimus.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20071101
-
Successful treatment of post-renal transplant gastric and pulmonary Kaposi's sarcoma with conversion to rapamycin treatment.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20071101
-
TOR signalling regulates mitotic commitment through the stress MAP kinase pathway and the Polo and Cdc2 kinases.
Nature cell biology 20071101
-
Coronary artery bypass grafting versus coronary implantation of sirolimus-eluting stents in patients with diabetic retinopathy.
The Annals of thoracic surgery 20071101
-
Three-year clinical outcomes after coronary stenting of chronic total occlusion using sirolimus-eluting stents: insights from the rapamycin-eluting stent evaluated at Rotterdam cardiology hospital-(RESEARCH) registry.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071101
-
Why do DES not alter long-term outcomes? Why would they, after all, it's a chronic disease.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071101
-
Sirolimus inhibits human pancreatic carcinoma cell proliferation by a mechanism linked to the targeting of mTOR/HIF-1 alpha/VEGF signaling.
IUBMB life 20071101
-
Laparoscopic incisional hernia repair after liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20071101
-
A randomized, phase II trial of two dose levels of temsirolimus (CCI-779) in patients with extensive-stage small-cell lung cancer who have responding or stable disease after induction chemotherapy: a trial of the Eastern Cooperative Oncology Group (E1500).
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20071101
-
Treatment of restenotic drug-eluting stents: an intravascular ultrasound analysis.
The Journal of invasive cardiology 20071101
-
The influence of immuosuppressive therapy on the development of CD4+CD25+ T cells after renal transplantation.
Transplantation proceedings 20071101
-
Anticancer effect of sirolimus in renal allograft recipients with de novo malignancies.
Transplantation proceedings 20071101
-
Comparison of long-term results of drug-eluting stent and bare metal stent implantation in heart transplant recipients with coronary artery disease.
Transplantation proceedings 20071101
-
Bevacizumab and rapamycin inhibit tumor growth in peritoneal model of human ovarian cancer.
Molecular cancer therapeutics 20071101
-
Autophagy in cardiovascular disease.
Trends in molecular medicine 20071101
-
Cancer after renal transplantation.
Current opinion in nephrology and hypertension 20071101
-
Comparison of long-term clinical outcome after sirolimus-eluting stent implantation in patients with and without hemodialysis.
International heart journal 20071101
-
Late multiple stent fractures following deployment of sirolimus-eluting stents for diffuse right coronary artery stenosis.
International heart journal 20071101
-
Temsirolimus for advanced renal cell carcinoma.
Clinical advances in hematology & oncology : H&O 20071101
-
A randomized phase II study of pemetrexed or RAD001 as second-line treatment of advanced non-small-cell lung cancer in elderly patients: treatment rationale and protocol dynamics.
Clinical lung cancer 20071101
-
[Clinical features of late stent thrombosis after successful sirolimus-eluting stent implantation].
Zhonghua xin xue guan bing za zhi 20071101
-
Sirolimus versus cyclosporine therapy increases circulating regulatory T cells, but does not protect renal transplant patients given alemtuzumab induction from chronic allograft injury.
Transplantation 20071027
-
Sirolimus modifies cholesterol homeostasis in hepatic cells: a potential molecular mechanism for sirolimus-associated dyslipidemia.
Transplantation 20071027
-
One-year results of the SCORPIUS study: a German multicenter investigation on the effectiveness of sirolimus-eluting stents in diabetic patients.
Journal of the American College of Cardiology 20071023
-
Features and parameters of drug-eluting stent deployment discoverable by intravascular ultrasound.
The American journal of cardiology 20071022
-
The significance of preclinical evaluation of sirolimus-, paclitaxel-, and zotarolimus-eluting stents.
The American journal of cardiology 20071022
-
Zotarolimus-eluting stents in patients with native coronary artery disease: clinical and angiographic outcomes in 1,317 patients.
The American journal of cardiology 20071022
-
Four-year clinical follow-up after implantation of the endeavor zotarolimus-eluting stent: ENDEAVOR I, the first-in-human study.
The American journal of cardiology 20071022
-
The relation between clinical features, angiographic findings, and the target lesion revascularization rate in patients receiving the endeavor zotarolimus-eluting stent for treatment of native coronary artery disease: an analysis of ENDEAVOR I, ENDEAVOR II, ENDEAVOR II Continued Access Registry, and ENDEAVOR III.
The American journal of cardiology 20071022
-
Intravascular ultrasound findings in ENDEAVOR II and ENDEAVOR III.
The American journal of cardiology 20071022
-
Real-world safety and efficacy of the endeavor zotarolimus-eluting stent: early data from the E-Five Registry.
The American journal of cardiology 20071022
-
Phase I study of everolimus in pediatric patients with refractory solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071020
-
Basal activation of p70S6K results in adipose-specific insulin resistance in protein-tyrosine phosphatase 1B -/- mice.
The Journal of biological chemistry 20071019
-
Rapamycin regulates the phosphorylation of rictor.
Biochemical and biophysical research communications 20071019
-
Normal phase and reverse phase HPLC-UV-MS analysis of process impurities for rapamycin analog ABT-578: application to active pharmaceutical ingredient process development.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071015
-
Comparison of outcomes using sirolimus-eluting stenting in diabetic versus nondiabetic patients with comparison of insulin versus non-insulin therapy in the diabetic patients.
The American journal of cardiology 20071015
-
Thymic stromal-derived lymphopoietin induces proliferation of pre-B leukemia and antagonizes mTOR inhibitors, suggesting a role for interleukin-7Ralpha signaling.
Cancer research 20071015
-
Sirolimus-related pulmonary toxicity mimicking 'asthma like' symptoms.
World journal of gastroenterology 20071014
-
Posttransplant Epstein-Barr virus related lymphoproliferative disorder with a primary cutaneous presentation.
Dermatology online journal 20071013
-
S6K1-mediated disassembly of mitochondrial URI/PP1gamma complexes activates a negative feedback program that counters S6K1 survival signaling.
Molecular cell 20071012
-
[Impact of sirolimus on collagen synthesis in vascular smooth muscle cells: experiment with rat].
Zhonghua yi xue za zhi 20071009
-
mTOR is the rapamycin-sensitive kinase that confers mechanically-induced phosphorylation of the hydrophobic motif site Thr(389) in p70(S6k).
FEBS letters 20071002
-
Long-term clinical outcomes with sirolimus-eluting coronary stents: five-year results of the RAVEL trial.
Journal of the American College of Cardiology 20071002
-
Sirolimus-eluting stent implantation aggravates endothelial vasomotor dysfunction in the infarct-related coronary artery in patients with acute myocardial infarction.
Journal of the American College of Cardiology 20071002
-
A meta-analysis of 16 randomized trials of sirolimus-eluting stents versus paclitaxel-eluting stents in patients with coronary artery disease.
Journal of the American College of Cardiology 20071002
-
The Emperor's new clothes: another cypher versus taxus post-hoc meta-analysis.
Journal of the American College of Cardiology 20071002
-
Reduced systemic inflammatory response to implantation of sirolimus-eluting stents in patients with stable coronary artery disease.
Atherosclerosis 20071001
-
PIM-2 is an independent regulator of chondrocyte survival and autophagy in the epiphyseal growth plate.
Journal of cellular physiology 20071001
-
Multiple sirolimus eluting stent fractures.
European heart journal 20071001
-
Comparison of in vivo acute stent recoil between the bioabsorbable everolimus-eluting coronary stent and the everolimus-eluting cobalt chromium coronary stent: insights from the ABSORB and SPIRIT trials.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001
-
Late vascular response at the edges of sirolimus analogous-eluting stents in diabetic patients: An intravascular ultrasound study.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001
-
Comparison of a treatment strategy combining CCI-779 plus DTIC versus DTIC monotreatment in human melanoma in SCID mice.
The Journal of investigative dermatology 20071001
-
Steroid and oxygen effects on eIF4F complex, mTOR, and ENaC translation in fetal lung epithelia.
American journal of respiratory cell and molecular biology 20071001
-
Determination of sirolimus in rabbit arteries using liquid chromatography separation and tandem mass spectrometric detection.
Biomedical chromatography : BMC 20071001
-
Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liver.
Blood 20071001
-
The application of ink-jet technology for the coating and loading of drug-eluting stents.
Annals of biomedical engineering 20071001
-
Translational control of nrf2 protein in activation of antioxidant response by oxidants.
Molecular pharmacology 20071001
-
Reversal of portal hypertension and hyperdynamic splanchnic circulation by combined vascular endothelial growth factor and platelet-derived growth factor blockade in rats.
Hepatology (Baltimore, Md.) 20071001
-
Initial clinical impact of drug eluting stents on coronary artery bypass graft surgery.
Interactive cardiovascular and thoracic surgery 20071001
-
Early experience with conversion to sirolimus in a pediatric renal transplant population.
Pediatric nephrology (Berlin, Germany) 20071001
-
Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study.
American journal of physiology. Lung cellular and molecular physiology 20071001
-
Methanol-associated matrix effects in electrospray ionization tandem mass spectrometry.
Clinical chemistry 20071001
-
Azoospermia in a renal transplant recipient during sirolimus (rapamycin) treatment.
Andrologia 20071001
-
Rapamycin: something old, something new, sometimes borrowed and now renewed.
Clinical pharmacology and therapeutics 20071001
-
Mammalian target of rapamycin inhibition halts the progression of proteinuria in a rat model of reduced renal mass.
Journal of the American Society of Nephrology : JASN 20071001
-
Sirolimus-associated infertility: case report and literature review of possible mechanisms.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20071001
-
Three-year health-related quality-of-life outcomes for sirolimus-treated kidney transplant patients after elimination of cyclosporine.
Transplant international : official journal of the European Society for Organ Transplantation 20071001
-
The role of mTOR inhibition in augmenting radiation induced autophagy.
Technology in cancer research & treatment 20071001
-
Effects of ciclosporin A, tacrolimus and sirolimus on cytokine production in neonatal immune cells.
Acta paediatrica (Oslo, Norway : 1992) 20071001
-
Comparison of triple versus dual antiplatelet therapy after drug-eluting stent implantation (from the DECLARE-Long trial).
The American journal of cardiology 20071001
-
Rapamycin reduces CCR5 mRNA levels in macaques: potential applications in HIV-1 prevention and treatment.
AIDS (London, England) 20071001
-
Sirolimus-eluting stent treatment for unprotected versus protected left main coronary artery disease in widespread clinical routine: 6-month and 3-year clinical follow-up results from the prospective multicentre German Cypher Registry.
Heart (British Cardiac Society) 20071001
-
Outcome in the elderly undergoing percutaneous coronary intervention with sirolimus-eluting stents: results from the prospective multicenter German Cypher Stent Registry.
American heart journal 20071001
-
Impact of diabetes mellitus on long-term outcomes in the drug-eluting stent era.
American heart journal 20071001
-
Impact of drug-eluting stents on clinical and angiographic outcomes in dialysis patients.
Circulation journal : official journal of the Japanese Circulation Society 20071001
-
Polymeric stents: degradable but strong.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001
-
The SIRIUS-DIRECT trial: a multi-center study of direct stenting using the sirolimus-eluting stent in patients with de novo native coronary artery lesions.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001
-
Direct stenting in the DES era: Can we do better?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001
-
The pros and cons of living on the edge.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001
-
Identification of everolimus metabolite patterns in trough blood samples of kidney transplant patients.
Therapeutic drug monitoring 20071001
-
Internal standard selection for the high-performance liquid chromatography tandem mass spectroscopy assay of everolimus in blood.
Therapeutic drug monitoring 20071001
-
Aging increases pulmonary veins arrhythmogenesis and susceptibility to calcium regulation agents.
Heart rhythm 20071001
-
Utility of sirolimus-eluting Cypher stents to reduce 12-month target vessel revascularization in saphenous vein graft stenoses: results of a multicenter 350-patient case-control study.
The Journal of invasive cardiology 20071001
-
Spontaneous coronary artery perforation secondary to a sirolimus-eluting stent infection.
The Journal of invasive cardiology 20071001
-
Preclinical testing of clinically applicable strategies for overcoming trastuzumab resistance caused by PTEN deficiency.
Clinical cancer research : an official journal of the American Association for Cancer Research 20071001
-
Sirolimus-based immunosuppression after cardiac transplantation: predictors of recovery from calcineurin inhibitor-induced renal dysfunction.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20071001
-
Treatment of unprotected left main coronary artery stenosis in a 5-year-old heart transplant patient using a sirolimus-eluting stent.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20071001
-
Sirolimus: efficacy in liver transplant patients with nephrotoxicity and renal insufficiency.
Transplantation proceedings 20071001
-
Drug-eluting stent implantation results in effective treatment of small coronary artery disease (DESIRE Small CAD).
Connecticut medicine 20071001
-
Sirolimus-associated diffuse alveolar hemorrhage in a renal transplant recipient on long-term anticoagulation.
Clinical nephrology 20071001
-
Immune responses to gene product of inducible promoters.
Current gene therapy 20071001
-
Anti-inflammatory effect of abciximab-coated stent in a porcine coronary restenosis model.
Journal of Korean medical science 20071001
-
Temsirolimus.
Drugs of today (Barcelona, Spain : 1998) 20071001
-
[Long-term clinical benefits of using active stents in diabetic patients: two year follow-up of a consecutive series of 122 patients].
Archives des maladies du coeur et des vaisseaux 20071001
-
Cancer and transplantation intersect at the mammalian target of rapamycin.
Transplantation 20070927
-
Use of everolimus as a rescue immunosuppressive therapy in liver transplant patients with neoplasms.
Transplantation 20070927
-
Comparative clinical outcomes of paclitaxel- and sirolimus-eluting stents: results from a large prospective multicenter registry--STENT Group.
Journal of the American College of Cardiology 20070925
-
Detecting binding interactions using microarrays of natural product extracts.
Journal of the American Chemical Society 20070919
-
Impact of vessel size on outcome after implantation of sirolimus-eluting and paclitaxel-eluting stents: a subgroup analysis of the SIRTAX trial.
Journal of the American College of Cardiology 20070918
-
Drug-eluting stent update 2007: part III: Technique and unapproved/unsettled indications (left main, bifurcations, chronic total occlusions, small vessels and long lesions, saphenous vein grafts, acute myocardial infarctions, and multivessel disease).
Circulation 20070918
-
Low-dose arsenic trioxide sensitizes glucocorticoid-resistant acute lymphoblastic leukemia cells to dexamethasone via an Akt-dependent pathway.
Blood 20070915
-
Quantification of cyclosporine A in peripheral blood mononuclear cells by liquid chromatography-electrospray mass spectrometry using a column-switching approach.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070915
-
Safety of drug-eluting stents in the coronary artery in ST-elevation myocardial infarction at a single high-volume medical center.
The American journal of cardiology 20070915
-
Correlates of clinical restenosis following intracoronary implantation of drug-eluting stents.
The American journal of cardiology 20070915
-
Drug-eluting stents and late stent thrombosis.
Lancet (London, England) 20070915
-
Outcomes associated with drug-eluting and bare-metal stents: a collaborative network meta-analysis.
Lancet (London, England) 20070915
-
Targeting human medulloblastoma: oncolytic virotherapy with myxoma virus is enhanced by rapamycin.
Cancer research 20070915
-
Expansion of human T regulatory type 1 cells in the microenvironment of cyclooxygenase 2 overexpressing head and neck squamous cell carcinoma.
Cancer research 20070915
-
Interferon-gamma induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase dependent mammalian target of rapamycin raptor complex 1 activation.
Circulation research 20070914
-
Interferon-gamma and intimal hyperplasia.
Circulation research 20070914
-
D-glucosamine inhibits proliferation of human cancer cells through inhibition of p70S6K.
Biochemical and biophysical research communications 20070907
-
RB1CC1 insufficiency causes neuronal atrophy through mTOR signaling alteration and involved in the pathology of Alzheimer's diseases.
Brain research 20070907
-
Temsirolimus for advanced renal-cell carcinoma.
The New England journal of medicine 20070906
-
Temsirolimus for advanced renal-cell carcinoma.
The New England journal of medicine 20070906
-
Coronary stent fracture and restenosis in the drug-eluting stent era: do we have clues of management?
International journal of cardiology 20070903
-
Cardiogenic shock caused by simultaneous subacute stent thrombosis after implantation of sirolimus-eluting stents.
International journal of cardiology 20070903
-
Comparison of angiographic patterns of in-stent restenosis between sirolimus- and paclitaxel-eluting stent.
International journal of cardiology 20070903
-
Understanding the drug-eluting stent trials.
The American journal of cardiology 20070903
-
Expansion and characteristics of human T regulatory type 1 cells in co-cultures simulating tumor microenvironment.
Cancer immunology, immunotherapy : CII 20070901
-
Specific mTOR inhibitor rapamycin enhances cytotoxicity induced by alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU) in human U251 malignant glioma cells.
Journal of neuro-oncology 20070901
-
Telomere 3' overhang-specific DNA oligonucleotides induce autophagy in malignant glioma cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070901
-
Genetic and pharmacologic evidence implicating the p85 alpha, but not p85 beta, regulatory subunit of PI3K and Rac2 GTPase in regulating oncogenic KIT-induced transformation in acute myeloid leukemia and systemic mastocytosis.
Blood 20070901
-
Improved blood compatibility of rapamycin-eluting stent by incorporating curcumin.
Colloids and surfaces. B, Biointerfaces 20070901
-
In vitro metabolic study of temsirolimus: preparation, isolation, and identification of the metabolites.
Drug metabolism and disposition: the biological fate of chemicals 20070901
-
Incidence of anemia in sirolimus-treated renal transplant recipients: the importance of preserving renal function.
Transplant international : official journal of the European Society for Organ Transplantation 20070901
-
Predictors of long-term outcome following liver transplantation for hepatocellular carcinoma: a single-center experience.
Transplant international : official journal of the European Society for Organ Transplantation 20070901
-
Reflex sympathetic dystrophy in a renal transplant patient treated with sirolimus.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070901
-
Golgi manganese transport is required for rapamycin signaling in Saccharomyces cerevisiae.
Genetics 20070901
-
Prevention of TGF-beta-induced apoptosis by interlukin-4 through Akt activation and p70S6K survival signaling pathways.
Apoptosis : an international journal on programmed cell death 20070901
-
Serotonin induces memory-like, rapamycin-sensitive hyperexcitability in sensory axons of aplysia that contributes to injury responses.
Journal of neurophysiology 20070901
-
Treatment options in steroid-refractory acute graft-versus-host disease following hematopoietic stem cell transplantation.
The Annals of pharmacotherapy 20070901
-
Use of sirolimus-eluting stents for treatment of in-stent restenosis: long-term follow-up.
Journal of cardiovascular medicine (Hagerstown, Md.) 20070901
-
Treatment of restenosis after bare-metal and drug-eluting stenting of an aorto-ostial lesion: challenges associated with excessive stent overhang.
Journal of cardiovascular medicine (Hagerstown, Md.) 20070901
-
Noble gases without anesthetic properties protect myocardium against infarction by activating prosurvival signaling kinases and inhibiting mitochondrial permeability transition in vivo.
Anesthesia and analgesia 20070901
-
A randomized comparison of sirolimus-eluting stent implantation with zotarolimus-eluting stent implantation for the treatment of total coronary occlusions: rationale and design of the PRImary Stenting of Occluded Native coronary arteries III (PRISON III) study.
American heart journal 20070901
-
A comparison of mortality, myocardial infarction, and repeated revascularization for sirolimus-eluting and paclitaxel-eluting coronary stents.
American heart journal 20070901
-
Nonrandomized comparison of coronary stenting under intravascular ultrasound guidance of direct stenting without predilation versus conventional predilation with a semi-compliant balloon versus predilation with a new scoring balloon.
The American journal of cardiology 20070901
-
Detailed intravascular ultrasound analysis of Zotarolimus-eluting phosphorylcholine-coated cobalt-chromium alloy stent in de novo coronary lesions (results from the ENDEAVOR II trial).
The American journal of cardiology 20070901
-
Stent thrombosis after sirolimus- and paclitaxel-eluting stent implantation in daily clinical practice: analysis of a single center registry.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070901
-
Sirolimus-eluting stent implantation for treatment of proximal left anterior descending coronary artery lesions: long-term outcome and predictors of adverse cardiac events.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070901
-
Treatment options in renal cell carcinoma: past, present and future.
Annals of oncology : official journal of the European Society for Medical Oncology 20070901
-
Phase I/II trial of temsirolimus combined with interferon alfa for advanced renal cell carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070901
-
The combination of novel low molecular weight inhibitors of RAF (LBT613) and target of rapamycin (RAD001) decreases glioma proliferation and invasion.
Molecular cancer therapeutics 20070901
-
Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle.
Cell metabolism 20070901
-
Fatal Epstein-Barr virus-associated lymphoproliferative disorder following treatment with a novel mTOR inhibitor for relapsed chronic lymphocytic leukemia leukemia cells.
Haematologica 20070901
-
Prospective assessment of discontinuation and reinitiation of erlotinib or gefitinib in patients with acquired resistance to erlotinib or gefitinib followed by the addition of everolimus.
Clinical cancer research : an official journal of the American Association for Cancer Research 20070901
-
Outlook of drug-eluting stent implantation for unprotected left main disease: insights on long-term clinical predictors.
The Journal of invasive cardiology 20070901
-
Sirolimus-eluting stent thrombosis several years after clopidogrel discontinuation.
The Journal of invasive cardiology 20070901
-
Sirolimus monotherapy as maintenance immunosuppression: single-center experience in 50 kidney transplant patients.
Transplantation proceedings 20070901
-
mTOR inhibitors: do they help preserve renal function?
Transplantation proceedings 20070901
-
Conversion from calcineurin inhibitors to sirolimus in kidney transplant patients reduces the urinary transforming growth factor-beta1 concentration.
Transplantation proceedings 20070901
-
Pharmacogenetics of tacrolimus and sirolimus in renal transplant patients: from retrospective analyses to prospective studies.
Transplantation proceedings 20070901
-
Evaluation of the efficacy and safety of the conversion from a calcineurin inhibitor to an everolimus-based therapy in maintenance renal transplant patients.
Transplantation proceedings 20070901
-
Early sirolimus use with cyclosporine elimination does not induce progressive proteinuria.
Transplantation proceedings 20070901
-
Use of the new proliferation signal inhibitor everolimus in renal transplant patients in Spain: preliminary results of the EVERODATA registry.
Transplantation proceedings 20070901
-
Study of anemia after late introduction of everolimus in the immunosuppressive treatment of renal transplant patients.
Transplantation proceedings 20070901
-
Conversion to sirolimus in posttransplant renal neoplasms.
Transplantation proceedings 20070901
-
mTOR inhibitors and their secondary effects in cardiac transplant recipients: a descriptive study.
Transplantation proceedings 20070901
-
Impact on renal function of the use of sirolimus in cardiac transplantation.
Transplantation proceedings 20070901
-
Sirolimus in renal transplantation.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070901
-
Sirolimus for visceral and cutaneous Kaposi's sarcoma in a renal-transplant recipient.
Clinical and experimental nephrology 20070901
-
New techniques and developments of stenting for infrainguinal arterial occlusive disease: are the results any better than balloon angioplasty alone?
Perspectives in vascular surgery and endovascular therapy 20070901
-
[Relationship between plasma C-reactive protein level and neointimal hyperplasia volume in patients with zotarolimus-eluting stents. Volumetric analysis by three-dimensional intracoronary ultrasound].
Revista espanola de cardiologia 20070901
-
Sunitinib, sorafenib and mTOR inhibitors in renal cancer.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20070901
-
Etanercept therapy for severe plaque psoriasis in a patient who underwent a liver transplant.
Cutis 20070901
-
Metastatic renal cell carcinoma: role of mammalian target of rapamycin inhibitors.
Clinical genitourinary cancer 20070901
-
Potential histologic and molecular predictors of response to temsirolimus in patients with advanced renal cell carcinoma.
Clinical genitourinary cancer 20070901
-
[3/3 Inhibitors of mTOR (sirolimus and everolimus)].
Soins; la revue de reference infirmiere 20070901
-
Drug-eluting stent implantation could be associated with long-term coronary endothelial dysfunction.
International heart journal 20070901
-
Very late stent thrombosis in late stent malapposition after sirolimus-eluting stent implantation.
International heart journal 20070901
-
Chemical control over protein-protein interactions: beyond inhibitors.
Combinatorial chemistry & high throughput screening 20070901
-
siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy.
The Journal of biological chemistry 20070831
-
Replacement of calcineurin-inhibitors with sirolimus as primary immunosuppression in stable cardiac transplant recipients.
Transplantation 20070827
-
PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex.
The Journal of biological chemistry 20070824
-
Off-label use of drug-eluting stents.
JAMA 20070822
-
Serial angioscopic evidence of incomplete neointimal coverage after sirolimus-eluting stent implantation: comparison with bare-metal stents.
Circulation 20070821
-
An activated mTOR/p70S6K signaling pathway in esophageal squamous cell carcinoma cell lines and inhibition of the pathway by rapamycin and siRNA against mTOR.
Cancer letters 20070818
-
Inhibition of mammalian target of rapamycin signaling by 2-(morpholin-1-yl)pyrimido[2,1-alpha]isoquinolin-4-one.
The Journal of biological chemistry 20070817
-
Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.
Oncogene 20070816
-
Intravascular ultrasound parameters associated with stent thrombosis after drug-eluting stent deployment.
The American journal of cardiology 20070815
-
Sequential quadruple immunosuppression including sirolimus in extended criteria and nonheartbeating donor kidney transplantation.
Transplantation 20070815
-
Incidence and predictors of drug-eluting stent thrombosis during and after discontinuation of thienopyridine treatment.
Circulation 20070814
-
Drug-eluting stents: dual antiplatelet therapy for every survivor?
Circulation 20070814
-
The effects of mTOR-Akt interactions on anti-apoptotic signaling in vascular endothelial cells.
The Journal of biological chemistry 20070810
-
Risk factors for stent thrombosis after implantation of sirolimus-eluting stents in diabetic and nondiabetic patients: the EVASTENT Matched-Cohort Registry.
Journal of the American College of Cardiology 20070807
-
[Lymphocele and kidney transplantation].
Orvosi hetilap 20070805
-
Structure of TOR and its complex with KOG1.
Molecular cell 20070803
-
PI 3-K signaling pathway suppresses PMA-induced expression of p21WAF1/Cip1 in human leukemia cells.
Molecular and cellular biochemistry 20070801
-
Snare extraction of a fractured coronary stent in a saphenous vein graft.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070801
-
Bifurcation stenting with a dedicated biolimus-eluting stent: X-ray visual enhancement of the final angiographic result with 'StentBoost Subtract'.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070801
-
Late drug-eluting stent thrombosis and erythropoietin: cause and effect?
Heart, lung & circulation 20070801
-
Sirolimus and paclitaxel provoke different vascular pathological responses after local delivery in a murine model for restenosis on underlying atherosclerotic arteries.
Heart (British Cardiac Society) 20070801
-
Influence of sirolimus on proteinuria in de novo kidney transplantation with expanded criteria donors: comparison of two CNI-free protocols.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070801
-
S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover.
American journal of physiology. Cell physiology 20070801
-
Mammalian target of rapamycin: master regulator of cell growth in the nervous system.
Histology and histopathology 20070801
-
Comparison between sirolimus- and paclitaxel-eluting stents in complex patient and lesions subsets.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070801
-
The Sirolimus-eluting coronary stent in daily routine practice in Germany: trends in indications over the years. Results from the prospective multi-centre German Cypher Stent Registry.
Clinical research in cardiology : official journal of the German Cardiac Society 20070801
-
Myocardial ischaemia-reperfusion injury is attenuated by intact glucagon like peptide-1 (GLP-1) in the in vitro rat heart and may involve the p70s6K pathway.
Cardiovascular drugs and therapy 20070801
-
Late-phase, protein synthesis-dependent long-term potentiation in hippocampal CA1 pyramidal neurones with destabilized microtubule networks.
British journal of pharmacology 20070801
-
Renoprotective effects of sirolimus in non-immune initiated focal segmental glomerulosclerosis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070801
-
Combination of the oncolytic adenovirus ICOVIR-5 with chemotherapy provides enhanced anti-glioma effect in vivo.
Cancer gene therapy 20070801
-
Long-term clinical benefit of sirolimus-eluting stent implantation in diabetic patients with de novo coronary stenoses: long-term results of the DIABETES trial.
European heart journal 20070801
-
Phase 1 trial of everolimus and gefitinib in patients with advanced nonsmall-cell lung cancer.
Cancer 20070801
-
The effect of sirolimus therapy on vaccine responses in transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070801
-
Increased iNOS-expressing macrophage in long-term surviving rat small-bowel grafts.
American journal of surgery 20070801
-
Three-year follow-up of the first prospective randomized comparison between paclitaxel and sirolimus stents: the TAXi-LATE trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070801
-
What kind of stent for you today and how would you like it prepared?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070801
-
Tuberous sclerosis complex: advances in diagnosis, genetics, and management.
Journal of the American Academy of Dermatology 20070801
-
Vascular pathology as a result of drug-eluting stents.
Heart (British Cardiac Society) 20070801
-
Parallel stenting using two sirolimus-eluting stents in an ectatic coronary artery stenosis.
Heart (British Cardiac Society) 20070801
-
Shared signaling networks active in B cells isolated from genetically distinct mouse models of lupus.
The Journal of clinical investigation 20070801
-
Culotte versus T-stenting in bifurcation lesions: immediate clinical and angiographic results and midterm clinical follow-up.
American heart journal 20070801
-
Neointimal progression and luminal narrowing in sirolimus-eluting stent treatment for bare metal in-stent restenosis: a quantitative intravascular ultrasound analysis.
American heart journal 20070801
-
Drug-eluting stents vs bare metal stents for the treatment of large coronary vessels.
American heart journal 20070801
-
External application of rapamycin-eluting film at anastomotic sites inhibits neointimal hyperplasia in a canine model.
The Annals of thoracic surgery 20070801
-
Modulation of cholesterol homeostasis by antiproliferative drugs in human pterygium fibroblasts.
Investigative ophthalmology & visual science 20070801
-
Predictors of target lesion revascularization and documented stent thrombosis beyond 30 days after sirolimus-eluting stent implantation: retrospective analysis in consecutive 1,070 angiographic follow-up lesions.
Circulation journal : official journal of the Japanese Circulation Society 20070801
-
Comparison of six-month angiographic and three-year outcomes after sirolimus-eluting stent implantation versus brachytherapy for bare metal in-stent restenosis.
The American journal of cardiology 20070801
-
Long-term clinical and angiographic outcomes of treatment of unprotected left main coronary artery stenosis with sirolimus-eluting stents.
The American journal of cardiology 20070801
-
Monitoring biological action of rapamycin in renal transplantation.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20070801
-
Analysis of programmed cell death in mouse fetal oocytes.
Reproduction (Cambridge, England) 20070801
-
Direct stenting limits sirolimus-eluting stent edge neointimal thickening.
Journal of vascular surgery 20070801
-
American Society of Clinical Oncology--43rd annual meeting. Translating research into practice.
IDrugs : the investigational drugs journal 20070801
-
Rationale for a phase I trial of erlotinib and the mammalian target of rapamycin inhibitor everolimus (RAD001) for patients with relapsed non small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 20070801
-
An improved bioluminescence resonance energy transfer strategy for imaging intracellular events in single cells and living subjects.
Cancer research 20070801
-
[The relationship of mTOR signaling pathway and histone acetylation in human gastric cancer cell lines].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20070801
-
Sirolimus as primary immunosuppressant for calcineurin inhibitor-related renal insufficiency after liver transplantation.
Hepatobiliary & pancreatic diseases international : HBPD INT 20070801
-
mTOR in tuberous sclerosis and other neurological disorders.
Epilepsia 20070801
-
Akt-induced endocrine therapy resistance is reversed by inhibition of mTOR signaling.
Annals of oncology : official journal of the European Society for Medical Oncology 20070801
-
Sirolimus-eluting versus bare-metal low-profile stent for renal artery treatment (GREAT Trial): angiographic follow-up after 6 months and clinical outcome up to 2 years.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20070801
-
Rapamycin inhibits multiple stages of c-Neu/ErbB2 induced tumor progression in a transgenic mouse model of HER2-positive breast cancer.
Molecular cancer therapeutics 20070801
-
Usefulness of drug eluting stent in percutaneous coronary intervention--a single center experience in Taiwan.
Journal of the Formosan Medical Association = Taiwan yi zhi 20070801
-
Short- and long-term clinical outcomes of coronary drug-eluting stent recipients presenting with chronic renal disease.
The Journal of invasive cardiology 20070801
-
Phase I trial of sirolimus combined with radiation and cisplatin in non-small cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20070801
-
The biology behind mTOR inhibition in sarcoma.
The oncologist 20070801
-
[Frequency and characteristics of incomplete stent apposition during and after sirolimus-eluting stent implantation].
Journal of cardiology 20070801
-
Economic analysis of the use of drug-eluting stents from the perspective of Belgian health care.
Acta cardiologica 20070801
-
[Comparison of effects between China made sirolimus-eluting stents and bare stents for treating patients with acute myocardial infarction].
Zhonghua xin xue guan bing za zhi 20070801
-
Drug eluting stents: focus on Cypher sirolimus-eluting coronary stents in the treatment of patients with bifurcation lesions.
Vascular health and risk management 20070801
-
Update on stents: recent studies on the TAXUS stent system in small vessels.
Vascular health and risk management 20070801
-
Mechanisms of mammalian target of rapamycin inhibition in sarcoma: present and future.
Expert review of anticancer therapy 20070801
-
Release profiles in drug-eluting stents: issues and uncertainties.
Journal of controlled release : official journal of the Controlled Release Society 20070731
-
Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy.
FEBS letters 20070724
-
Increased late mortality after sirolimus-eluting stents versus bare-metal stents in diseased saphenous vein grafts: results from the randomized DELAYED RRISC Trial.
Journal of the American College of Cardiology 20070717
-
'Crying fire in a theater' or a 'confirmatory sighting?'.
Journal of the American College of Cardiology 20070717
-
Sirolimus-based graft-versus-host disease prophylaxis protects against cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation: a cohort analysis.
Blood 20070715
-
BK virus-associated nephropathy in sirolimus-treated renal transplant patients: incidence, course, and clinical outcomes.
Transplantation 20070715
-
RAD001 inhibits human ovarian cancer cell proliferation, enhances cisplatin-induced apoptosis, and prolongs survival in an ovarian cancer model.
Clinical cancer research : an official journal of the American Association for Cancer Research 20070715
-
Hypoxia-inducible factor 1alpha is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif.
The Journal of biological chemistry 20070713
-
Subacute stent thrombosis happening at discharge.
International journal of cardiology 20070710
-
Two-year clinical follow-up after sirolimus-eluting versus bare-metal stent implantation assisted by systematic glycoprotein IIb/IIIa Inhibitor Infusion in patients with myocardial infarction: results from the STRATEGY study.
Journal of the American College of Cardiology 20070710
-
Does the use of paclitaxel or rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent?
Sao Paulo medical journal = Revista paulista de medicina 20070705
-
Differential effects of the immunosuppressive agents cyclosporin A, tacrolimus and sirolimus on drug transport by multidrug resistance proteins.
Cancer chemotherapy and pharmacology 20070701
-
Clinical impact of in-stent late loss after drug-eluting coronary stent implantation.
European heart journal 20070701
-
Rapamycin together with herceptin significantly increased anti-tumor efficacy compared to either alone in ErbB2 over expressing breast cancer cells.
International journal of cancer 20070701
-
Rapamycin retards growth and causes marked alterations in the growth plate of young rats.
Pediatric nephrology (Berlin, Germany) 20070701
-
Isolated left pulmonary artery: interventional stenting of a persistent fifth aortic arch.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701
-
Insulin potentiates Ca2+ signaling and phosphatidylinositol 4,5-bisphosphate hydrolysis induced by Gq protein-coupled receptor agonists through an mTOR-dependent pathway.
Endocrinology 20070701
-
Rapamycin blunts nutrient stimulation of eIF4G, but not PKCepsilon phosphorylation, in skeletal muscle.
American journal of physiology. Endocrinology and metabolism 20070701
-
Rapamycin prevents thyroid hormone-induced cardiac hypertrophy.
Endocrinology 20070701
-
The effect of sirolimus- or cyclosporine-based immunosuppression effects on T-cell subsets in vivo.
Kidney international 20070701
-
The acute phase protein alpha2-macroglobulin induces rat ventricular cardiomyocyte hypertrophy via ERK1,2 and PI3-kinase/Akt pathways.
Cardiovascular research 20070701
-
Subclinical rejection and sirolimus associated edema in renal allograft recipients.
Transplant international : official journal of the European Society for Organ Transplantation 20070701
-
Transient sirolimus serum levels after implantation of a sirolimus eluting stent in an infant.
Clinical research in cardiology : official journal of the German Cardiac Society 20070701
-
Mammalian target of rapamycin in the human placenta regulates leucine transport and is down-regulated in restricted fetal growth.
The Journal of physiology 20070701
-
Vascular endothelial growth factor as a survival factor for human islets: effect of immunosuppressive drugs.
Diabetologia 20070701
-
Removal of FKBP12/12.6 from endothelial ryanodine receptors leads to an intracellular calcium leak and endothelial dysfunction.
Arteriosclerosis, thrombosis, and vascular biology 20070701
-
Rapamycin reduces CCR5 density levels on CD4 T cells, and this effect results in potentiation of enfuvirtide (T-20) against R5 strains of human immunodeficiency virus type 1 in vitro.
Antimicrobial agents and chemotherapy 20070701
-
Vascular responses to drug eluting stents: importance of delayed healing.
Arteriosclerosis, thrombosis, and vascular biology 20070701
-
Contrasting effects of cyclosporine and rapamycin in de novo generation of alloantigen-specific regulatory T cells.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070701
-
Inhibition of endogenous MHC class II-restricted antigen presentation by tacrolimus (FK506) via FKBP51.
European journal of immunology 20070701
-
The localization of nuclear exporters of the importin-beta family is regulated by Snf1 kinase, nutrient supply and stress.
Biochimica et biophysica acta 20070701
-
Treatment of patients with advanced soft tissue sarcoma: disappointment or challenge?
Current opinion in oncology 20070701
-
Insulin-like growth factor-I has different effects on myogenin induction and cell cycle progression in human alveolar and embryonal rhabdomyosarcoma cells.
International journal of oncology 20070701
-
Molecular impacts of rapamycin-based drug combinations: combining rapamycin with gemcitabine or imatinib mesylate (Gleevec) in a human leiomyosarcoma model.
International journal of oncology 20070701
-
Possible involvement of persistent activity of the mammalian target of rapamycin pathway in the cisplatin resistance of AFP-producing gastric cancer cells.
Cancer biology & therapy 20070701
-
Confined late stent thrombosis following clopidogrel withdrawal in a patient with multi-segment sirolimus-eluting stent implants.
Journal of cardiovascular medicine (Hagerstown, Md.) 20070701
-
Tumour-derived fibroblast growth factor-2 exerts lymphangiogenic effects through Akt/mTOR/p70S6kinase pathway in rat lymphatic endothelial cells.
European journal of cancer (Oxford, England : 1990) 20070701
-
One pathway, many products.
Nature chemical biology 20070701
-
Risk of stent thrombosis after sirolimus or paclitaxel eluting coronary stent implantation.
British journal of clinical pharmacology 20070701
-
Revascularization for ischemic LV dysfunction: stents or surgery?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701
-
Comparison of drug-eluting stents with bare metal stents in unselected patients with acute myocardial infarction.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701
-
Treatment of drug-eluting stent restenosis with the same versus different drug-eluting stent.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701
-
Two-by-two factorial comparison of high-bolus-dose tirofiban followed by standard infusion versus abciximab and sirolimus-eluting versus bare-metal stent implantation in patients with acute myocardial infarction: design and rationale for the MULTI-STRATEGY trial.
American heart journal 20070701
-
Sirolimus-eluting stents compared with standard stents in the treatment of patients with primary angioplasty.
American heart journal 20070701
-
Revascularization in severe left ventricular dysfunction: outcome comparison of drug-eluting stent implantation versus coronary artery by-pass grafting.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701
-
Modified T-stenting with intentional protrusion of the side-branch stent within the main vessel stent to ensure ostial coverage and facilitate final kissing balloon: the T-stenting and small protrusion technique (TAP-stenting). Report of bench testing and first clinical Italian-Korean two-centre experience.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701
-
The role of mTOR inhibitors for treatment of sarcomas.
Current oncology reports 20070701
-
Uneventful thoracic healing with everolimus after aortic valve replacement.
The Annals of thoracic surgery 20070701
-
Therapeutics of vein graft intimal hyperplasia: 100 years on.
The Annals of thoracic surgery 20070701
-
Duration of clopidogrel therapy after placement of drug-eluting intracoronary stent.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070701
-
Late restenosis following sirolimus-eluting stent implantation.
The American journal of cardiology 20070701
-
Long-term clinical outcomes and thrombosis rates of sirolimus-eluting versus paclitaxel-eluting stents in an unselected population with coronary artery disease (REWARDS registry).
The American journal of cardiology 20070701
-
Intravascular ultrasound comparison of sirolimus-eluting stent versus bare metal stent implantation in diseased saphenous vein grafts (from the RRISC [Reduction of Restenosis In Saphenous Vein Grafts With Cypher Sirolimus-Eluting Stent] trial).
The American journal of cardiology 20070701
-
Combined therapeutic effects of vinblastine and rapamycin on human neuroblastoma growth, apoptosis, and angiogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 20070701
-
Interleukin-17 and airway inflammation: a longitudinal airway biopsy study after lung transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070701
-
Observational study with everolimus (Certican) in combination with low-dose cyclosporine in de novo heart transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070701
-
Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy.
Cancer cell 20070701
-
Angiographic and histological assessment of successfully treated late acute stent thrombosis secondary to a sirolimus-eluting stent.
European heart journal 20070701
-
Sensitizing HER2-overexpressing cancer cells to luteolin-induced apoptosis through suppressing p21(WAF1/CIP1) expression with rapamycin.
Molecular cancer therapeutics 20070701
-
The influence of low (81 mg) versus high (325 mg) doses of ASA on the incidence of sirolimus-eluting stent thrombosis.
The Journal of invasive cardiology 20070701
-
A three-dimensional intravascular ultrasound comparison between the new zotarolimus-eluting stent (ZoMaxx) and the non-drug-eluting TriMaxx stent.
The Journal of invasive cardiology 20070701
-
Temsirolimus in the treatment of advanced renal cell carcinoma.
Annals of oncology : official journal of the European Society for Medical Oncology 20070701
-
Sirolimus toxicity and vascular endothelial growth factor release from islet and renal cell lines.
Transplantation 20070627
-
Long-term safety and efficacy of drug-eluting stents: two-year results of the REAL (REgistro AngiopLastiche dell'Emilia Romagna) multicenter registry.
Circulation 20070626
-
Stress-responsive Gln3 localization in Saccharomyces cerevisiae is separable from and can overwhelm nitrogen source regulation.
The Journal of biological chemistry 20070622
-
[Present circumstance around percutaneous coronary intervention (PCI): before and after drug eluting stent (DES) introduction].
Nihon Hoshasen Gijutsu Gakkai zasshi 20070620
-
Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis.
Journal of the American College of Cardiology 20070619
-
Comparable clinical outcomes with paclitaxel- and sirolimus-eluting stents in unrestricted contemporary practice.
Journal of the American College of Cardiology 20070619
-
Phosphorylation of ribosomal p70 S6 kinase and rapamycin sensitivity in human colorectal cancer.
Cancer letters 20070618
-
Bystin in human cancer cells: intracellular localization and function in ribosome biogenesis.
The Biochemical journal 20070615
-
Six-month clinical and angiographic results of a dedicated drug-eluting stent for the treatment of coronary bifurcation narrowings.
The American journal of cardiology 20070615
-
The effects of granulocyte-colony stimulating factor in bare stent and sirolimus-eluting stent in pigs following myocardial infarction.
International journal of cardiology 20070612
-
Drug eluting stent implantation for the treatment of symptomatic myocardial bridging is associated with favorable peri-procedural results and short-term outcomes.
International journal of cardiology 20070612
-
Sch9 is a major target of TORC1 in Saccharomyces cerevisiae.
Molecular cell 20070608
-
Sirolimus-induced posterior reversible encephalopathy.
Neurology 20070605
-
Coronary artery stent fracture.
The international journal of cardiovascular imaging 20070601
-
Stent fracture: an unusual cause of late restenosis after sirolimus-eluting stent placement.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070601
-
Target lesion revascularisation in patients treated with a sirolimus-eluting or paclitaxel-eluting stent.
Heart (British Cardiac Society) 20070601
-
The rapid activation of protein synthesis by growth hormone requires signaling through mTOR.
American journal of physiology. Endocrinology and metabolism 20070601
-
Long-term outcomes of bifurcation lesions after implantation of drug-eluting stents with the 'mini-crush technique'.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070601
-
Identification and characterization of a functional Candida albicans homolog of the Saccharomyces cerevisiae TCO89 gene.
FEMS yeast research 20070601
-
Anti-atherosclerotic effects of sirolimus on human vascular smooth muscle cells.
American journal of physiology. Heart and circulatory physiology 20070601
-
The Mammalian target of rapamycin pathway regulates nutrient-sensitive glucose uptake in man.
Diabetes 20070601
-
Caerulein-induced intracellular pancreatic zymogen activation is dependent on calcineurin.
American journal of physiology. Gastrointestinal and liver physiology 20070601
-
Rapamycin-induced hypokalaemic nephropathy in a middle-aged hypertensive male.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070601
-
Late experimental amebic liver abscess in hamster is inhibited by cyclosporine and N-acetylcysteine.
Experimental and molecular pathology 20070601
-
An antibody delivery system for regulated expression of therapeutic levels of monoclonal antibodies in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 20070601
-
Rapamycin stimulates arginine influx through CAT2 transporters in human endothelial cells.
Biochimica et biophysica acta 20070601
-
Comparison of the CEDIA and MEIA assays for the measurement of sirolimus in organ transplant recipients.
Clinical biochemistry 20070601
-
Physiologically based pharmacokinetic (PBPK) modeling of everolimus (RAD001) in rats involving non-linear tissue uptake.
Journal of pharmacokinetics and pharmacodynamics 20070601
-
The influence of cyclosporin A on lymphocyte attenuator expression.
Journal of autoimmunity 20070601
-
mTOR-inhibitors simultaneously inhibit proliferation and basal IL-6 synthesis of human coronary artery endothelial cells.
International immunopharmacology 20070601
-
Late incomplete apposition after drug-eluting stent implantation: incidence and potential for adverse clinical outcomes.
European heart journal 20070601
-
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.
Nature chemical biology 20070601
-
Is there delayed restenosis in patients with coronary artery disease treated with sirolimus-eluting stent?
Coronary artery disease 20070601
-
Severe intimal hyperplasia after sirolimus eluting stent deployment: evaluation by optical coherence tomography.
Heart (British Cardiac Society) 20070601
-
Stimulating the cell's appetite for itself.
Nature chemical biology 20070601
-
Assessment and validation of the MS/MS fragmentation patterns of the macrolide immunosuppressant everolimus.
Journal of mass spectrometry : JMS 20070601
-
Antigenic disparity impacts outcome of agonism but not blockade of costimulatory pathways in experimental transplant models.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070601
-
Early withdrawal of calcineurin inhibitors and rescue immunosuppression with sirolimus-based therapy in renal transplant recipients with moderate to severe renal dysfunction.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070601
-
Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance.
Journal of immunology (Baltimore, Md. : 1950) 20070601
-
Compared effect of immunosuppressive drugs cyclosporine A and rapamycin on cholesterol homeostasis key enzymes CYP27A1 and HMG-CoA reductase.
Basic & clinical pharmacology & toxicology 20070601
-
Stent fracture-unusual cause of DES restenosis.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070601
-
Sirolimus as part of immunosuppressive therapy for refractory chronic graft-versus-host disease.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20070601
-
Sirolimus-induced pneumonitis following liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20070601
-
Subclavian-vertebral artery bifurcation stenting using drug-eluting stents: a report of two cases using different techniques.
The Journal of invasive cardiology 20070601
-
Prevention of acute rejection and allograft vasculopathy by everolimus in cardiac transplants recipients: a 24-month analysis.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070601
-
Low-dose tacrolimus/sirolimus and steroid withdrawal in heart recipients is highly efficacious.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070601
-
Sirolimus-induced alveolar hemorrhage.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070601
-
Possible everolimus-induced, severe, reversible encephalopathy after cardiac transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070601
-
Endothelial Akt signaling is rate-limiting for rapamycin inhibition of mouse mammary tumor progression.
Cancer research 20070601
-
Comparative characterization of cellular and molecular anti-restenotic profiles of paclitaxel and sirolimus. Implications for local drug delivery.
Thrombosis and haemostasis 20070601
-
Sirolimus and liver transplantation: clinical implications for hepatocellular carcinoma.
Expert opinion on pharmacotherapy 20070601
-
Is sirolimus a nephrotoxic drug? A report of five cases.
Transplantation proceedings 20070601
-
Protective effects of sirolimus by attenuating connective tissue growth factor expression in human chronic allograft nephropathy.
Transplantation proceedings 20070601
-
Lack of hepatotoxicity upon sirolimus addition to a calcineurin inhibitor-based regimen in hepatitis virus-positive renal transplant recipients.
Transplantation proceedings 20070601
-
Rejection episodes and 3-year graft survival under sirolimus and tacrolimus treatment after adult intestinal transplantation.
Transplantation proceedings 20070601
-
Comparison of stent graft, sirolimus stent, and bare metal stent implanted in patients with acute coronary syndrome: clinical and angiographic follow-up.
Croatian medical journal 20070601
-
Formulation of sirolimus eye drops and corneal permeation studies.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20070601
-
Progressive multifocal leukoencephalopathy: a case study.
Progress in transplantation (Aliso Viejo, Calif.) 20070601
-
Use and long-term outcome of bare metal stent implantation in the drug-eluting stent era.
Journal of cardiology 20070601
-
Impact of highly asymmetric stent expansion after sirolimus-eluting stent implantation on twelve-month clinical outcomes.
Journal of cardiology 20070601
-
[Limitation on efficacy of sirolimus-eluting stent implantation in patients on hemodialysis].
Journal of cardiology 20070601
-
Restenosis developing over one year after implantation with a sirolimus-eluting stent: two case reports.
Journal of cardiology 20070601
-
Rational use of drug-eluting stents: a comparison of different policies.
Critical pathways in cardiology 20070601
-
[Pilot study of a cell membrane like biomimetic drug-eluting coronary stent].
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20070601
-
Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma.
The New England journal of medicine 20070531
-
Long-term renal transplant function in recipient of simultaneous kidney and pancreas transplant maintained with two prednisone-free maintenance immunosuppressive combinations: tacrolimus/mycophenolate mofetil versus tacrolimus/sirolimus.
Transplantation 20070527
-
Sirolimus conversion in liver transplant recipients with renal dysfunction: a prospective, randomized, single-center trial.
Transplantation 20070527
-
Firebird sirolimus eluting stent versus bare mental stent in patients with ST-segment elevation myocardial infarction.
Chinese medical journal 20070520
-
Sirolimus eluting stent fracture following angioplasty of diffuse in-stent restenosis in the right coronary artery.
International journal of cardiology 20070516
-
Complete fracture of sirolimus-eluting stent detected by multislice computed tomography.
International journal of cardiology 20070516
-
Overlapping hybrid stenting with a sirolimus-eluting stent and a bare metal stent.
International journal of cardiology 20070516
-
Engineering small molecule specificity in nearly identical cellular environments.
Bioorganic & medicinal chemistry letters 20070515
-
Meta-analysis of randomized trials of drug-eluting stents versus bare metal stents in patients with diabetes mellitus.
The American journal of cardiology 20070515
-
Percutaneous coronary revascularization using a trilayer metal phosphorylcholine-coated zotarolimus-eluting stent.
The American journal of cardiology 20070515
-
De novo sirolimus-based immunosuppression after liver transplantation for hepatocellular carcinoma: long-term outcomes and side effects.
Transplantation 20070515
-
CD154 blockade, sirolimus, and donor-specific transfusion prevents renal allograft rejection in cynomolgus monkeys despite homeostatic T-cell activation.
Transplantation 20070515
-
Late introduction of sirolimus induces anemia in renal transplant recipients.
Transplantation 20070515
-
Randomized trial of Sirolimus-Eluting Stent Versus Bare-Metal Stent in Acute Myocardial Infarction (SESAMI).
Journal of the American College of Cardiology 20070515
-
Drug-eluting stents for acute myocardial infarction.
Journal of the American College of Cardiology 20070515
-
Outcomes and complications associated with off-label and untested use of drug-eluting stents.
JAMA 20070509
-
Clinical outcomes and stent thrombosis following off-label use of drug-eluting stents.
JAMA 20070509
-
The enigma of drug-eluting stents: hope, hype, humility, and advancing patient care.
JAMA 20070509
-
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
Circulation 20070508
-
What to do about late incomplete stent apposition?
Circulation 20070508
-
Incomplete stent apposition and very late stent thrombosis after drug-eluting stent implantation.
Circulation 20070508
-
The rapamycin-binding domain of the protein kinase mammalian target of rapamycin is a destabilizing domain.
The Journal of biological chemistry 20070504
-
CYPHER versus TAXUS stent for bifurcation lesions beyond 30 days-long-term follow-up results.
International journal of cardiology 20070502
-
Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells.
Leukemia research 20070501
-
Calcineurin-independent inhibition of KV1.3 by FK-506 (tacrolimus): a novel pharmacological property.
American journal of physiology. Cell physiology 20070501
-
Impact of renal insufficiency on clinical and angiographic outcomes following percutaneous coronary intervention with sirolimus-eluting stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070501
-
Factors predictive of cardiac events and restenosis after sirolimus-eluting stent implantation in small coronary arteries.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070501
-
Diagnosis of de novo localized thrombotic microangiopathy by surveillance biopsy.
Pediatric nephrology (Berlin, Germany) 20070501
-
Simultaneous LC-MS-MS determination of cyclosporine A, tacrolimus, and sirolimus in whole blood as well as mycophenolic acid in plasma using common pretreatment procedure.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501
-
Rapamycin-regulated control of antiangiogenic tumor therapy following rAAV-mediated gene transfer.
Molecular therapy : the journal of the American Society of Gene Therapy 20070501
-
Kidney function after islet transplant alone in type 1 diabetes: impact of immunosuppressive therapy on progression of diabetic nephropathy.
Diabetes care 20070501
-
Randomized comparative trial of a thin-strut bare metal cobalt-chromium stent versus a sirolimus-eluting stent for coronary revascularization.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070501
-
Sirolimus-eluting biodegradable poly-L-lactide stent for peripheral vascular application: a preliminary study in porcine carotid arteries.
The Journal of surgical research 20070501
-
Comparison of fluorescent polarization immunoassay (FPIA) versus HPLC to measure everolimus blood concentrations in clinical transplantation.
Clinica chimica acta; international journal of clinical chemistry 20070501
-
Vascular remodeling and antitumoral effects of mTOR inhibition in a rat model of hepatocellular carcinoma.
Journal of hepatology 20070501
-
Incidence and predictors of target vessel revascularization after sirolimus-eluting stent treatment for proximal left anterior descending artery stenoses among 2274 patients from the prospective multicenter German Cypher Stent Registry.
Clinical research in cardiology : official journal of the German Cardiac Society 20070501
-
Rapamycin, not cyclosporine, permits thymic generation and peripheral preservation of CD4+ CD25+ FoxP3+ T cells.
Bone marrow transplantation 20070501
-
The role of proliferation signal inhibitors in post-transplant malignancies.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501
-
Restenosis following thin-strut bare-metal stents versus thick-strut drug-eluting stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070501
-
Posterior reversible encephalopathy syndrome due to sirolimus.
Bone marrow transplantation 20070501
-
Sirolimus impairs wound healing.
Langenbeck's archives of surgery 20070501
-
Stent thrombosis with drug-eluting stents: a re-examination of the evidence.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070501
-
An in vitro cytologic assay for evaluation of the KIT signaling pathway in gastrointestinal stromal tumors.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20070501
-
Rapamycin, a specific inhibitor of the mammalian target of rapamycin, suppresses lymphangiogenesis and lymphatic metastasis.
Cancer science 20070501
-
Influence of the UGT2B7 promoter region and exon 2 polymorphisms and comedications on Acyl-MPAG production in vitro and in adult renal transplant patients.
Pharmacogenetics and genomics 20070501
-
Reversal of loss of glomerular filtration rate in children with transplant nephropathy after switch to everolimus and low-dose cyclosporine A.
Pediatric transplantation 20070501
-
Reversal of tacrolimus-related hypertrophic cardiomyopathy after conversion to rapamycin in a pediatric liver transplant recipient.
Pediatric transplantation 20070501
-
Sirolimus is not always responsible for new-onset proteinuria after conversion for chronic allograft nephropathy.
Pediatric transplantation 20070501
-
Therapeutic effect of a new immunosuppressive agent, everolimus, on interleukin-10 gene-deficient mice with colitis.
Clinical and experimental immunology 20070501
-
Calcineurin inhibitors and rapamycin: cancer protection or promotion?
Experimental dermatology 20070501
-
mTOR as a potential therapeutic target for treatment of keloids and excessive scars.
Experimental dermatology 20070501
-
Meta-analysis of clinical trials on use of drug-eluting stents for treatment of acute myocardial infarction.
American heart journal 20070501
-
Pretransplant HLA antibodies are associated with reduced graft survival after clinical islet transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070501
-
Kaposi's sarcoma in renal transplant recipients--the impact of proliferation signal inhibitors.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501
-
Use of proliferation signal inhibitors in non-melanoma skin cancer following renal transplantation.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501
-
Post-transplant lymphoproliferative disorder--the potential of proliferation signal inhibitors.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501
-
Use of proliferation signal inhibitors in the management of post-transplant malignancies--clinical guidance.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501
-
Conversion to sirolimus-based immunosuppression in maintenance liver transplantation patients.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20070501
-
Costimulation blockade--what will the future bring?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501
-
Do the results of the new trials change the standard treatment of metastatic renal cell cancer?
Onkologie 20070501
-
Sirolimus treatment for pulmonary lymphangioleiomyomatosis.
Annals of internal medicine 20070501
-
Uncertainty.
Nature clinical practice. Gastroenterology & hepatology 20070501
-
Impact of the Food and Drug Administration's Public Health Notification on the adoption of drug-eluting stents.
The American journal of cardiology 20070501
-
The Akt/mammalian target of rapamycin signal transduction pathway is activated in high-risk myelodysplastic syndromes and influences cell survival and proliferation.
Cancer research 20070501
-
Mammalian target of rapamycin activation impairs hepatocytic differentiation and targets genes moderating lipid homeostasis and hepatocellular growth.
Cancer research 20070501
-
Targeted therapies for soft-tissue sarcomas.
Expert review of anticancer therapy 20070501
-
A pharmacokinetic interaction between clarithromycin and sirolimus in kidney transplant recipient.
Current drug metabolism 20070501
-
Effect of rapamycin on wound healing: an experimental study.
Transplantation proceedings 20070501
-
An assay for the determination of sirolimus levels in the lymphocyte of transplant patients.
Transplantation proceedings 20070501
-
Lymphedema: an unusual complication of sirolimus therapy.
Transplantation proceedings 20070501
-
Optimization of immunosuppressive drug monitoring in children.
Transplantation proceedings 20070501
-
Complete regression of cutaneous B-cell lymphoma in a renal transplant patient after conversion from cyclosporin to sirolimus.
Transplantation proceedings 20070501
-
Retinal injury as an early manifestation of posttransplant thrombotic microangiopathy: recovery with plasma exchanges and conversion to sirolimus--case report and review of the literature.
Transplantation proceedings 20070501
-
Stent fracture and restenosis after placement of a drug-eluting device in the vertebral artery origin and treatment with the stent-in-stent technique. Report of two cases.
Journal of neurosurgery 20070501
-
Conversion to combined therapy with sirolimus and mycophenolate mofetil improved renal function in stable renal transplant recipients.
Journal of the Formosan Medical Association = Taiwan yi zhi 20070501
-
Sirolimus-eluting stents in real-world patients with ST-segment elevation acute myocardial infarction.
International heart journal 20070501
-
Two cases of very late stent thrombosis after implantation of a sirolimus-eluting stent presenting as AMI.
International heart journal 20070501
-
[Angioplasty stenting with Sirolimus (rapamycin) eluting stents in type 2 diabetic patients].
Revista medica de Chile 20070501
-
Clinical development of mTOR inhibitors: a focus on lymphoma.
Reviews on recent clinical trials 20070501
-
Rapamycin enhances the number of alloantigen-induced human CD103+CD8+ regulatory T cells in vitro.
Transplantation 20070427
-
Rapamycin inhibits proliferation of Epstein-Barr virus-positive B-cell lymphomas through modulation of cell-cycle protein expression.
Transplantation 20070427
-
Regulation of survivin expression by IGF-1/mTOR signaling.
Oncogene 20070426
-
Clopidogrel and long-term outcomes after drug-eluting stent implantation.
JAMA 20070425
-
Clopidogrel and long-term outcomes after drug-eluting stent implantation.
JAMA 20070425
-
Clopidogrel and long-term outcomes after drug-eluting stent implantation.
JAMA 20070425
-
Clopidogrel and long-term outcomes after drug-eluting stent implantation.
JAMA 20070425
-
[Late stent thrombosis with drug eluting stents: disturbing signals on the radar].
Ugeskrift for laeger 20070423
-
p21-activated kinase 1 is activated through the mammalian target of rapamycin/p70 S6 kinase pathway and regulates the replication of hepatitis C virus in human hepatoma cells.
The Journal of biological chemistry 20070420
-
Distinct EBV and CMV reactivation patterns following antibody-based immunosuppressive regimens in patients with severe aplastic anemia.
Blood 20070415
-
Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML.
Blood 20070415
-
Mammalian target of rapamycin is activated in human gastric cancer and serves as a target for therapy in an experimental model.
International journal of cancer 20070415
-
PI3K(p110alpha) inhibitors as anti-cancer agents: minding the heart.
Cell cycle (Georgetown, Tex.) 20070415
-
Comparison of three-year clinical outcome of sirolimus- and paclitaxel-eluting stents versus bare metal stents in patients with ST-segment elevation myocardial infarction (from the RESEARCH and T-SEARCH Registries).
The American journal of cardiology 20070415
-
Evaluation by optical coherence tomography of neointimal coverage of sirolimus-eluting stent three months after implantation.
The American journal of cardiology 20070415
-
Analysis of 36 reported cases of late thrombosis in drug-eluting stents placed in coronary arteries.
The American journal of cardiology 20070415
-
Safety of sirolimus-eluting stenting and its effect on restenosis in patients with unstable angina pectoris (a SIRIUS substudy).
The American journal of cardiology 20070415
-
Cyphering the complexity of coronary artery disease using the syntax score to predict clinical outcome in patients with three-vessel lumen obstruction undergoing percutaneous coronary intervention.
The American journal of cardiology 20070415
-
Therapeutic effect of rapamycin on gallbladder cancer in a transgenic mouse model.
Cancer research 20070415
-
Kidney transplantation with sirolimus and mycophenolate mofetil-based immunosuppression: 5-year results of a randomized prospective trial compared to calcineurin inhibitor drugs.
Transplantation 20070415
-
Sirolimus-eluting stent showed better one-year outcomes than paclitaxel-eluting stent in a real life setting of coronary intervention in Koreans.
International journal of cardiology 20070412
-
AKT activity regulates the ability of mTOR inhibitors to prevent angiogenesis and VEGF expression in multiple myeloma cells.
Oncogene 20070405
-
Late stent thrombosis: a not negligible issue after drug-eluting stent implantation.
Chinese medical journal 20070405
-
Sirolimus-eluting cobalt alloyed stents in treating patients with coronary artery disease: six-month angiographic and one-year clinical follow-up result. A prospective, historically controlled, multi-center clinical study.
Chinese medical journal 20070405
-
Long-term outcomes following drug-eluting stent implantation in unprotected left main bifurcation lesions.
Chinese medical journal 20070405
-
Drug-eluting stent for the treatment of small coronary lesion: comparison between sirolimus- and paclitaxel-eluting stent.
Chinese medical journal 20070405
-
A comparison of clinical and angiographic outcomes after Excel bioabsorbable polymer versus Firebird durable polymer rapamycin-eluting stent for the treatment of coronary artery disease in a 'real world' setting: six-month follow-up results.
Chinese medical journal 20070405
-
Type-D personality predicts chronic anxiety following percutaneous coronary intervention in the drug-eluting stent era.
Journal of affective disorders 20070401
-
A HPLC-mass spectrometric method suitable for the therapeutic drug monitoring of everolimus.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070401
-
Neointimal coverage of sirolimus-eluting stents at 6-month follow-up: evaluated by optical coherence tomography.
European heart journal 20070401
-
Extended follow-up of methotrexate-free immunosuppression using sirolimus and tacrolimus in related and unrelated donor peripheral blood stem cell transplantation.
Blood 20070401
-
Mechanism of apoptosis induced by IFN-alpha in human myeloma cells: role of Jak1 and Bim and potentiation by rapamycin.
Cellular signalling 20070401
-
A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling.
The Biochemical journal 20070401
-
Rapamycin is a neuroprotective treatment for traumatic brain injury.
Neurobiology of disease 20070401
-
Rapamycin: brain excitability studied in vitro.
Epilepsia 20070401
-
Ssh4, Rcr2 and Rcr1 affect plasma membrane transporter activity in Saccharomyces cerevisiae.
Genetics 20070401
-
Chronic alcohol consumption alters mammalian target of rapamycin (mTOR), reduces ribosomal p70s6 kinase and p4E-BP1 levels in mouse cerebral cortex.
Experimental neurology 20070401
-
Accurate determination of an immunosuppressant in stented swine tissues with LC-MS/MS.
Analytical and bioanalytical chemistry 20070401
-
Inhibition of the mammalian target of rapamycin impedes lymphangiogenesis.
Kidney international 20070401
-
Mutasynthesis - uniting chemistry and genetics for drug discovery.
Trends in biotechnology 20070401
-
Gonadal impact of target of rapamycin inhibitors (sirolimus and everolimus) in male patients: an overview.
Transplant international : official journal of the European Society for Organ Transplantation 20070401
-
Hemolytic uremic syndrome following Campath-1H induction.
Transplant international : official journal of the European Society for Organ Transplantation 20070401
-
No recurrence of Kaposi's sarcoma in a case of renal retransplantation under a calcineurin inhibitor free immunosuppressive regimen: first report.
Transplant international : official journal of the European Society for Organ Transplantation 20070401
-
Differential modulation of mitogen driven proliferation and homeostasis driven proliferation of T cells by rapamycin, Ly294002 and chlorophyllin.
Molecular immunology 20070401
-
The effect of immunosuppressive drug rapamycin on regulatory CD4+CD25+Foxp3+T cells in mice.
Transplant immunology 20070401
-
Rapamycin inhibits cell growth by induction of apoptosis on hepatocellular carcinoma cells in vitro.
Transplant immunology 20070401
-
Effect of sirolimus treatment on gene expression in renal transplant patients.
World journal of surgery 20070401
-
PI3K/AKT/mTOR hypersignaling in autoimmune lymphoproliferative disease engendered by the epistatic interplay of Sle1b and FASlpr.
International immunology 20070401
-
Limitation by p70 S6 kinase of platelet-derived growth factor-BB-induced interleukin 6 synthesis in osteoblast-like MC3T3-E1 cells.
Metabolism: clinical and experimental 20070401
-
Drug-eluting stent-induced left anterior descending coronary artery aneurysm: repair by pericardial patch--where are we headed?
The Annals of thoracic surgery 20070401
-
Incidence of side-effects of ticlopidine after sirolimus-eluting stent implantation.
Circulation journal : official journal of the Japanese Circulation Society 20070401
-
Effects of immunosuppressive drugs on in vitro neogenesis of human islets: mycophenolate mofetil inhibits the proliferation of ductal cells.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070401
-
Diabetic retinopathy and coronary implantation of sirolimus-eluting stents.
Journal of interventional cardiology 20070401
-
Potential therapeutic applications of autophagy.
Nature reviews. Drug discovery 20070401
-
Recommendations for the use of everolimus (Certican) in heart transplantation: results from the second German-Austrian Certican Consensus Conference.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070401
-
Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 20070401
-
Comparison of vessel response following sirolimus-eluting stent implantation as assessed by serial 3-D intravascular ultrasound study.
The Journal of invasive cardiology 20070401
-
Sirolimus-eluting stents for the treatment of bare-metal in-stent restenosis: long-term clinical follow up.
The Journal of invasive cardiology 20070401
-
Late stent thrombosis associated with coronary aneurysm formation after sirolimus-eluting stent implantation.
The Journal of invasive cardiology 20070401
-
Activation of mitogen-activated protein kinase by hepatocyte growth factor is stimulated by both alpha1- and beta2-adrenergic agonists in primary cultures of adult rat hepatocytes.
Journal of pharmacological sciences 20070401
-
[Effect of Rapamycin on CD4(+) CD25(+) regulatory T cells in allo-transplantation tolerance model].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20070401
-
How to control lymphangiogenesis: a novel role for rapamycin.
Kidney international 20070401
-
[Induction effect of rapamycin combined paclitaxel on apoptosis of ovarian cancer cell lines A2780 and SKOV3 and the molecular mechanism].
Ai zheng = Aizheng = Chinese journal of cancer 20070401
-
Drug-eluting stents show delayed healing: paclitaxel more pronounced than sirolimus.
European heart journal 20070401
-
Zotarolimus, a novel sirolimus analogue with potent anti-proliferative activity on coronary smooth muscle cells and reduced potential for systemic immunosuppression.
Journal of cardiovascular pharmacology 20070401
-
Conversion from a calcineurin inhibitor-based immunosuppressive regimen to everolimus in renal transplant recipients: effect on renal function and proteinuria.
Transplantation proceedings 20070401
-
Case report of a kidney transplant recipient converted to everolimus due to malignancy: resolution of bronchiolitis obliterans organizing pneumonia without everolimus discontinuation.
Transplantation proceedings 20070401
-
Sirolimus-eluting versus bare stents after suboptimal infrapopliteal angioplasty for critical limb ischemia: enduring 1-year angiographic and clinical benefit.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20070401
-
Participation of phosphatidyl inositol 3-kinase/protein kinase B and ERK1/2 pathways in interleukin-1beta stimulation of lactate production in Sertoli cells.
Reproduction (Cambridge, England) 20070401
-
Cost-effectiveness of sirolimus-eluting stents in percutaneous coronary interventions in Brazil.
Arquivos brasileiros de cardiologia 20070401
-
Sirolimus-eluting coronary stents: a review.
Vascular health and risk management 20070401
-
[Procedural success and 10-month outcome between Cypher and TAXUS drug-eluting stents for the treatment of in-stent restenosis].
Zhonghua xin xue guan bing za zhi 20070401
-
[Very late stent thrombosis after implantation of sirolimus eluting coronary stents].
Zhonghua xin xue guan bing za zhi 20070401
-
[Re-occurred acute myocardial infarction caused by very late thrombosis 36 months after implantation of sirolimus eluting stent: a case report].
Zhonghua xin xue guan bing za zhi 20070401
-
Does addition of estradiol improve the efficacy of a rapamycin-eluting stent? Results of the ISAR-PEACE randomized trial.
Journal of the American College of Cardiology 20070327
-
Epithelial-to-mesenchymal transition of human proximal tubular epithelial cells: effects of rapamycin, mycophenolate, cyclosporin, azathioprine, and methylprednisolone.
Transplantation 20070327
-
Dual EGFR and mTOR targeting in squamous cell carcinoma models, and development of early markers of efficacy.
British journal of cancer 20070326
-
Silencing mammalian target of rapamycin signaling by small interfering RNA enhances rapamycin-induced autophagy in malignant glioma cells.
Oncogene 20070322
-
Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism.
Oncogene 20070322
-
For organ transplant recipients, cancer threatens long-term survival.
Journal of the National Cancer Institute 20070321
-
Age-based clinical and angiographic outcomes after sirolimus-eluting stent implantation in patients with coronary artery disease.
Chinese medical journal 20070320
-
Target of rapamycin (TOR) signaling controls epithelial morphogenesis in the vertebrate intestine.
Developmental biology 20070315
-
Two endoplasmic reticulum-associated degradation (ERAD) systems for the novel variant of the mutant dysferlin: ubiquitin/proteasome ERAD(I) and autophagy/lysosome ERAD(II).
Human molecular genetics 20070315
-
Results and predictors of angiographic restenosis and long-term adverse cardiac events after drug-eluting stent implantation for aorto-ostial coronary artery disease.
The American journal of cardiology 20070315
-
Frequency of coronary arterial late angiographic stent thrombosis (LAST) in the first six months: outcomes with drug-eluting stents versus bare metal stents.
The American journal of cardiology 20070315
-
In vivo and in vitro effect of sirolimus on insulin secretion.
Transplantation 20070315
-
Rapamycin promotes emergence of IL-10-secreting donor lymphocyte infusion-derived T cells without compromising their graft-versus-leukemia reactivity.
Transplantation 20070315
-
RAD001 (Everolimus) delays tumor onset and progression in a transgenic mouse model of ovarian cancer.
Cancer research 20070315
-
[Pharmacodynamics of China-made rapamycin-polylactide-co-glycolide peripheral arterial eluting stent membrane: in vitro experiment].
Zhonghua yi xue za zhi 20070313
-
AKT and CDK5/p35 mediate brain-derived neurotrophic factor induction of DARPP-32 in medium size spiny neurons in vitro.
The Journal of biological chemistry 20070309
-
Stent thrombosis in randomized clinical trials of drug-eluting stents.
The New England journal of medicine 20070308
-
Long-term outcomes with drug-eluting stents versus bare-metal stents in Sweden.
The New England journal of medicine 20070308
-
Analysis of 14 trials comparing sirolimus-eluting stents with bare-metal stents.
The New England journal of medicine 20070308
-
Safety and efficacy of sirolimus- and paclitaxel-eluting coronary stents.
The New England journal of medicine 20070308
-
A pooled analysis of data comparing sirolimus-eluting stents with bare-metal stents.
The New England journal of medicine 20070308
-
Unanswered questions--drug-eluting stents and the risk of late thrombosis.
The New England journal of medicine 20070308
-
Late thrombosis of a drug-eluting stent overlapped in the in-stent restenotic lesion of a bare metal stent.
International journal of cardiology 20070302
-
Regulation of translation factors eIF4GI and 4E-BP1 during recovery of protein synthesis from inhibition by p53.
Cell death and differentiation 20070301
-
The YCR079w gene confers a rapamycin-resistant function and encodes the sixth type 2C protein phosphatase in Saccharomyces cerevisiae.
FEMS yeast research 20070301
-
Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling.
Blood 20070301
-
Rapamycin inhibits proliferation of estrogen-receptor-positive breast cancer cells.
The Journal of surgical research 20070301
-
mTOR-dependent synthesis of Bcl-3 controls the retraction of fibrin clots by activated human platelets.
Blood 20070301
-
Metabolism of sirolimus in the presence or absence of cyclosporine by genotyped human liver microsomes and recombinant cytochromes P450 3A4 and 3A5.
Drug metabolism and disposition: the biological fate of chemicals 20070301
-
In vivo inhibition of human hepatocellular carcinoma related angiogenesis by vinblastine and rapamycin.
Histology and histopathology 20070301
-
Sirolimus causes relaxation of human vascular smooth muscle: a novel action of sirolimus mediated via ATP-sensitive potassium channels.
The Journal of pharmacology and experimental therapeutics 20070301
-
Modeling of degradation and drug release from a biodegradable stent coating.
Journal of biomedical materials research. Part A 20070301
-
Role of protein tyrosine phosphatases in the regulation of interferon-{gamma}-induced macrophage nitric oxide generation: implication of ERK pathway and AP-1 activation.
Journal of leukocyte biology 20070301
-
Opposite effects of tor1 and tor2 on nitrogen starvation responses in fission yeast.
Genetics 20070301
-
Negative regulation by p70 S6 kinase of FGF-2-stimulated VEGF release through stress-activated protein kinase/c-Jun N-terminal kinase in osteoblasts.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20070301
-
Utility of three-dimensional reconstruction of coronary angiography to guide percutaneous coronary intervention.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070301
-
One-year results with extended-release tacrolimus/MMF, tacrolimus/MMF and cyclosporine/MMF in de novo kidney transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070301
-
Mycophenolate mofetil/sirolimus compared to other common immunosuppressive regimens in kidney transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070301
-
Calcineurin inhibitor-free protocols: risks and benefits.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20070301
-
Mycotic pseudoaneurysm of the left circumflex coronary artery: a fatal complication following drug-eluting stent implantation.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070301
-
Clobetasol ameliorates aphthous ulceration in renal transplant patients on sirolimus.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070301
-
A clickable inhibitor reveals context-dependent autoactivation of p90 RSK.
Nature chemical biology 20070301
-
FK506 binding protein 12/12.6 depletion increases endothelial nitric oxide synthase threonine 495 phosphorylation and blood pressure.
Hypertension (Dallas, Tex. : 1979) 20070301
-
Proliferation signal inhibitors in cardiac transplantation.
Current opinion in cardiology 20070301
-
New advances in antirejection therapy.
Current opinion in cardiology 20070301
-
Regulatory T cells and T cell depletion: role of immunosuppressive drugs.
Journal of the American Society of Nephrology : JASN 20070301
-
Pulmonary alveolar proteinosis: a rare pulmonary toxicity of sirolimus.
Transplant international : official journal of the European Society for Organ Transplantation 20070301
-
Chemical rescue of cleft palate and midline defects in conditional GSK-3beta mice.
Nature 20070301
-
Rapamycin-mediated G1 arrest involves regulation of the Cdk inhibitor Sic1 in Saccharomyces cerevisiae.
Molecular microbiology 20070301
-
The treatment of multifocal choroiditis associated choroidal neovascularization with sirolimus (rapamycin).
Acta ophthalmologica Scandinavica 20070301
-
Repeated drug-eluting stent implantation for drug-eluting stent restenosis: the same or a different stent.
American heart journal 20070301
-
Angiographic analysis of pattern of late luminal loss in sirolimus- and paclitaxel-eluting stents.
The American journal of cardiology 20070301
-
Comparison of effectiveness of bare metal stents versus drug-eluting stents in large (> or =3.5 mm) coronary arteries.
The American journal of cardiology 20070301
-
An anti-aging drug today: from senescence-promoting genes to anti-aging pill.
Drug discovery today 20070301
-
Mammalian target of rapamycin inhibitors as possible adjuvant therapy for microscopic residual disease in head and neck squamous cell cancer.
Cancer research 20070301
-
Monitoring antitumor efficacy of rapamycin in Kaposi sarcoma.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20070301
-
Islet transplantation.
The New England journal of medicine 20070301
-
In-stent pseudo-restenosis due to an organized thrombus six months after implantation of a sirolimus-eluting stent.
The Journal of invasive cardiology 20070301
-
Sirolimus-eluting stent implantation outside a previous stent.
The Journal of invasive cardiology 20070301
-
Sirolimus-associated chronic pyogenic periungual infection.
Kidney international 20070301
-
Reduced progression of endometrial hyperplasia with oral mTOR inhibition in the Pten heterozygote murine model.
American journal of obstetrics and gynecology 20070301
-
Calcineurin inhibitor-free immunosuppression using everolimus (Certican) in maintenance heart transplant recipients: 6 months' follow-up.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070301
-
Acute sirolimus pulmonary toxicity in an infant heart transplant recipient: case report and literature review.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070301
-
[Gene therapy for osteoarticular disorders].
Medecine sciences : M/S 20070301
-
The role of immunosuppressive drugs in aggravating renal ischemia and reperfusion injury.
Transplantation proceedings 20070301
-
A role for HO-1 in renal function impairment in animals subjected to ischemic and reperfusion injury and treated with immunosuppressive drugs.
Transplantation proceedings 20070301
-
Proteinuria in transplant patients associated with sirolimus.
Transplantation proceedings 20070301
-
The effects of rapamycin in the progression of renal fibrosis.
Transplantation proceedings 20070301
-
Five-year follow-up after late conversion from calcineurin inhibitors to sirolimus in patients with chronic renal allograft dysfunction.
Transplantation proceedings 20070301
-
Is the malononitrilamide FK778 better for the prevention of acute or chronic rejection?
Transplantation proceedings 20070301
-
Upstream signaling inhibition enhances rapamycin effect on growth of kidney cancer cells.
Urology 20070301
-
Left main coronary artery stenosis: state-of-the-art.
Current problems in cardiology 20070301
-
In-stent restenosis: 3 novel solutions show promise for heart patients. Stopping regrowth of plaque inside stents is a priority in reducing the need for repeat revascularizations.
DukeMedicine healthnews 20070301
-
Initial and long-term outcomes of sirolimus-eluting stents for calcified lesions compared with bare-metal stents.
International heart journal 20070301
-
Chemokines and chemokine receptors in renal transplantation--from bench to bedside.
Acta physiologica Hungarica 20070301
-
[Treatment of intrastent restenosis by drug eluting stents: experience from one cardiology centre].
Archives des maladies du coeur et des vaisseaux 20070301
-
[Analysis of the mechanisms of thrombosis after implantation of drug-eluting stents].
Zhonghua nei ke za zhi 20070301
-
[Short and long-term therapeutic efficacy of drug-eluting stents (Firebird) for the treatment of coronary artery disease].
Zhonghua xin xue guan bing za zhi 20070301
-
Immunosuppression strategies in kidney transplantation.
Medicine and health, Rhode Island 20070301
-
Sirolimus: defining nephrotoxicity in the renal transplant recipient.
Clinical journal of the American Society of Nephrology : CJASN 20070301
-
High sirolimus levels may induce focal segmental glomerulosclerosis de novo.
Clinical journal of the American Society of Nephrology : CJASN 20070301
-
Nanomedicines in renal transplant rejection--focus on sirolimus.
International journal of nanomedicine 20070301
-
Effects of everolimus on cellular and humoral immune processes leading to chronic allograft nephropathy in a rat model with sensitized recipients.
Transplantation 20070227
-
[Expression of connective tissue growth factor in renal interstitial fibrosis after ureteral obstruction and effects of rapamycin thereupon: experiment with rats].
Zhonghua yi xue za zhi 20070227
-
Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from a large two-institutional cohort study.
Lancet (London, England) 20070224
-
Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.
The Journal of biological chemistry 20070223
-
A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation.
Oncogene 20070222
-
[Drug eluting stents: long term results in clinical practice. Comparison between rapamycin and paclitaxel eluting stents].
Medicina clinica 20070217
-
Rottlerin inhibits human T cell responses.
Biochemical pharmacology 20070215
-
Incidence and clinical impact of coronary stent fracture after sirolimus-eluting stent implantation.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070215
-
Stent fracture associated with drug-eluting stents: clinical characteristics and implications.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070215
-
Detection of vascular endothelial growth factor (VEGF) and VEGF receptors Flt-1 and KDR in canine mastocytoma cells.
Veterinary immunology and immunopathology 20070215
-
Treatment of recurrent pulmonary vein stenoses with endovascular stenting and adjuvant oral sirolimus.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070215
-
A role for mammalian target of rapamycin in regulating T cell activation versus anergy.
Journal of immunology (Baltimore, Md. : 1950) 20070215
-
Long-term graft outcomes after steroid withdrawal in African American kidney transplant recipients receiving sirolimus and tacrolimus.
Transplantation 20070215
-
TSC1 sets the rate of ribosome export and protein synthesis through nucleophosmin translation.
Cancer research 20070215
-
Akt/TSC/mTOR activation by the KSHV G protein-coupled receptor: emerging insights into the molecular oncogenesis and treatment of Kaposi's sarcoma.
Cell cycle (Georgetown, Tex.) 20070215
-
Selective clearance of macrophages in atherosclerotic plaques by autophagy.
Journal of the American College of Cardiology 20070213
-
Amino acid limitation induces expression of ATF5 mRNA at the post-transcriptional level.
Life sciences 20070206
-
Randomized comparison of sirolimus and paclitaxel drug-eluting stents for long lesions in the left anterior descending artery: an intravascular ultrasound study.
Journal of the American College of Cardiology 20070206
-
Effectiveness of drug-eluting stents in patients with bare-metal in-stent restenosis: meta-analysis of randomized trials.
Journal of the American College of Cardiology 20070206
-
Development of coronary aneurysm after drug-eluting stent implantation.
Annals of internal medicine 20070206
-
ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.
Cell death and differentiation 20070201
-
Case report: Corticosteroid-resistant nephrotic syndrome: treatment with rapamune.
Pediatric nephrology (Berlin, Germany) 20070201
-
mTOR signaling in the hippocampus is necessary for memory formation.
Neurobiology of learning and memory 20070201
-
Rapamycin inhibits the growth and muscle-sparing effects of clenbuterol.
Journal of applied physiology (Bethesda, Md. : 1985) 20070201
-
Antiproliferative activity of RAD001 (everolimus) as a single agent and combined with other agents in mantle cell lymphoma.
Leukemia 20070201
-
Antiproliferative agents alter vascular plasminogen activator inhibitor-1 expression: a potential prothrombotic mechanism of drug-eluting stents.
Arteriosclerosis, thrombosis, and vascular biology 20070201
-
Aspects of mTOR biology and the use of mTOR inhibitors in non-Hodgkin's lymphoma.
Cancer treatment reviews 20070201
-
Is late stent thrombosis in drug-eluting stents a real clinical issue? A single-center experience and review of the literature.
Clinical research in cardiology : official journal of the German Cardiac Society 20070201
-
Short- and long-term effects of cytochalasin D, paclitaxel and rapamycin on wall thickening in experimental porcine vein grafts.
Cardiovascular research 20070201
-
[Coronary stents and anaesthesia: it is time to have national data].
Annales francaises d'anesthesie et de reanimation 20070201
-
Relocation of minimal luminal diameter after bare metal and drug-eluting stent implantation: incidence and impact on angiographic late loss.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070201
-
CYP3A5 genotype markedly influences the pharmacokinetics of tacrolimus and sirolimus in kidney transplant recipients.
Clinical pharmacology and therapeutics 20070201
-
Effectiveness and safety of the sirolimus-eluting stents coated with bioabsorbable polymer coating in human coronary arteries.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070201
-
Late restenosis following placement of a sirolimus eluting stent for in-stent restenosis.
Heart, lung & circulation 20070201
-
Combining an mTOR antagonist and receptor tyrosine kinase inhibitors for the treatment of prostate cancer.
Cancer biology & therapy 20070201
-
Severe psoriasis treated with a new macrolide: everolimus.
The British journal of dermatology 20070201
-
Pharmacodynamics of T-cell function for monitoring immunosuppression.
Cell proliferation 20070201
-
Switching from tacrolimus to sirolimus halts the appearance of new sebaceous neoplasms in Muir-Torre syndrome.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070201
-
Emerging thrombotic effects of drug eluting stents.
Arteriosclerosis, thrombosis, and vascular biology 20070201
-
Evaluation of the efficacy and safety of a slow conversion from calcineurin inhibitor- to sirolimus-based therapies in maintenance renal-transplant patients presenting with moderate renal insufficiency.
Transplant international : official journal of the European Society for Organ Transplantation 20070201
-
Induction of chimerism in rhesus macaques through stem cell transplant and costimulation blockade-based immunosuppression.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070201
-
Further delineation of the continuous human neoplastic enterochromaffin cell line, KRJ-I, and the inhibitory effects of lanreotide and rapamycin.
Journal of molecular endocrinology 20070201
-
Impaired endothelial vasomotor function after sirolimus-eluting stent implantation.
Circulation journal : official journal of the Japanese Circulation Society 20070201
-
Late angiographic stent thrombosis after sirolimus-eluting stent implantation.
Circulation journal : official journal of the Japanese Circulation Society 20070201
-
Novel bioengineered small caliber vascular graft with excellent one-month patency.
The Annals of thoracic surgery 20070201
-
Impact of pharmacometric reviews on new drug approval and labeling decisions--a survey of 31 new drug applications submitted between 2005 and 2006.
Clinical pharmacology and therapeutics 20070201
-
Comparison of drug-eluting versus bare metal stents on later frequency of acute myocardial infarction and death.
The American journal of cardiology 20070201
-
Outcome of overlapping heterogenous drug-eluting stents and of overlapping drug-eluting and bare metal stents.
The American journal of cardiology 20070201
-
Sirolimus therapy of focal segmental glomerulosclerosis is associated with nephrotoxicity.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20070201
-
The clinical outcome of percutaneous treatment of bifurcation lesions in multivessel coronary artery disease with the sirolimus-eluting stent: insights from the Arterial Revascularization Therapies Study part II (ARTS II).
European heart journal 20070201
-
Bivalirudin versus heparin plus glycoprotein IIb/IIIa inhibitors in drug-eluting stent implantations in the absence of acute myocardial infarction: clinical and economic results.
The Journal of invasive cardiology 20070201
-
Bivalirudin and DES: a PCI strategy that pays.
The Journal of invasive cardiology 20070201
-
Fractured DES with a patent coronary artery: clinical implications.
The Journal of invasive cardiology 20070201
-
Targeting mammalian target of rapamycin (mTOR) for health and diseases.
Drug discovery today 20070201
-
Interplay of PI3K and cAMP/PKA signaling, and rapamycin-hypersensitivity in TGFbeta1 enhancement of FSH-stimulated steroidogenesis in rat ovarian granulosa cells.
The Journal of endocrinology 20070201
-
American Society of Hematology--48th Annual Meeting and Exposition. Treatments for leukemia and lymphoma. 9-12 December 2006 Orlando, FL, USA.
IDrugs : the investigational drugs journal 20070201
-
American Society of Hematology--48th Annual Meeting and Exposition. Updates on therapies. 9-12 December 2006 Orlando, FL, USA.
IDrugs : the investigational drugs journal 20070201
-
Randomized, double-blind, multicenter study of the Endeavor zotarolimus-eluting phosphorylcholine-encapsulated stent for treatment of native coronary artery lesions. Clinical and angiographic results of the ENDEAVOR II Trial.
Minerva cardioangiologica 20070201
-
Keeping a high standard in quantitative analyses, meta-analyses, and systematic reviews.
European heart journal 20070201
-
TCT Daily: Cypher more effective for long lesions.
Journal of interventional cardiology 20070201
-
TCT Daily: ZOMAXX I--mixed results with zotarolimus-eluting stent.
Journal of interventional cardiology 20070201
-
Adverse clinical events in patients treated with sirolimus-eluting stents: the impact of Type D personality.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20070201
-
Validation of immunological biomarkers for the pharmacodynamic monitoring of immunosuppressive drugs in humans.
Therapeutic drug monitoring 20070201
-
Serum sickness-like reactions after placement of sirolimus-eluting stents.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20070201
-
Requirements of phosphatidylinositol-3 kinase and mammalian target of rapamycin for estrogen-induced proliferation in uterine leiomyoma- and myometrium-derived cell lines.
American journal of obstetrics and gynecology 20070201
-
Optimizing the development of targeted agents in pancreatic cancer: tumor fine-needle aspiration biopsy as a platform for novel prospective ex vivo drug sensitivity assays.
Molecular cancer therapeutics 20070201
-
Combination of sublethal concentrations of epidermal growth factor receptor inhibitor and microtubule stabilizer induces apoptosis of glioblastoma cells.
Molecular cancer therapeutics 20070201
-
Symptomatic failure after sirolimus-eluting stent implantation: a rare but challenging condition.
The Canadian journal of cardiology 20070201
-
Orally administered rapamycin does not modify rat aortic vascular tone.
Journal of cardiovascular pharmacology 20070201
-
[Progress on reasech of drug-coated stent].
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20070201
-
Thrombotic microangiopathy in a sirolimus-treated renal transplant patient receiving gemcitabine for lung cancer.
Clinical nephrology 20070201
-
[Janus tacrolimus-eluting carbostent. Immediate and medium-term clinical results].
Revista espanola de cardiologia 20070201
-
The Development of rapamycin as an orphan drug.
Clinical advances in hematology & oncology : H&O 20070201
-
Possible predictors of target lesion revascularization after drug-eluting stent implantation.
Journal of cardiology 20070201
-
Proximal left anterior descending coronary artery revascularization with drug-eluting stents.
Arquivos brasileiros de cardiologia 20070201
-
Impact of stable versus unstable coronary artery disease on 1-year outcome in elective patients undergoing multivessel revascularization with sirolimus-eluting stents: a subanalysis of the ARTS II trial.
Journal of the American College of Cardiology 20070130
-
Unilateral upper extremity edema associated with sirolimus in a heart transplant patient.
Transplantation 20070127
-
Ligand-regulated peptide aptamers that inhibit the 5'-AMP-activated protein kinase.
Journal of molecular biology 20070126
-
A 'silent' polymorphism in the MDR1 gene changes substrate specificity.
Science (New York, N.Y.) 20070126
-
Nutrient starvation promotes condensin loading to maintain rDNA stability.
The EMBO journal 20070124
-
[Comparison of stenting with sirolimus eluting stent and spot stenting with small vessel stent in treatment of small vessels with long lesions].
Zhonghua yi xue za zhi 20070123
-
Phorbol 12-myristate 13-acetate and serum synergize to promote rapamycin-insensitive cell proliferation via protein kinase C-eta.
Oncogene 20070118
-
Coronary artery stenting in a patient with angina pectoris caused by coronary artery dissection after blunt chest trauma.
International journal of cardiology 20070118
-
Dilemma of drug-eluting stent implantation in a patient with systemic lupus erythematosus.
International journal of cardiology 20070118
-
Long-term outcomes after management of restenosis or thrombosis of drug-eluting stents.
Journal of the American College of Cardiology 20070116
-
Overexpression of the mTOR alpha4 phosphoprotein activates protein phosphatase 2A and increases Stat1alpha binding to PIAS1.
Molecular and cellular endocrinology 20070115
-
Evaluating the activity of temsirolimus in neuroendocrine cancer.
British journal of cancer 20070115
-
Sirolimus does not reduce receptor-mediated endocytosis of albumin in proximal tubule cells.
Transplantation 20070115
-
[Drug-eluting or bare-metal stents in interventional cardiology. Theory and practice].
Medizinische Klinik (Munich, Germany : 1983) 20070115
-
The role of mammalian target of rapamycin inhibitors in the treatment of advanced renal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 20070115
-
Clopidogrel use and long-term clinical outcomes after drug-eluting stent implantation.
JAMA 20070110
-
Does clopidogrel each day keep stent thrombosis away?
JAMA 20070110
-
Direct and indirect comparison meta-analysis demonstrates the superiority of sirolimus- versus paclitaxel-eluting stents across 5854 patients.
International journal of cardiology 20070102
-
Coronary collateral function long after drug-eluting stent implantation.
Journal of the American College of Cardiology 20070102
-
Attenuated coronary collateral function after drug-eluting stent implantation: a new downside of drug-eluting stents?
Journal of the American College of Cardiology 20070102
-
Reactive oxygen species regulate insulin-induced VEGF and HIF-1alpha expression through the activation of p70S6K1 in human prostate cancer cells.
Carcinogenesis 20070101
-
Rapamycin at subimmunosuppressive levels inhibits mesangial cell proliferation and extracellular matrix production.
American journal of physiology. Renal physiology 20070101
-
A kinetically trapped intermediate of FK506 binding protein forms in vitro: chaperone machinery dominates protein folding in vivo.
Protein expression and purification 20070101
-
Intramural delivery of Sirolimus prevents vascular remodeling following balloon injury.
Biochimica et biophysica acta 20070101
-
Effects of rapamycin on cell proliferation and phosphorylation of mTOR and p70(S6K) in HepG2 and HepG2 cells overexpressing constitutively active Akt/PKB.
Biochimica et biophysica acta 20070101
-
Acetaldehyde promotes rapamycin-dependent activation of p70(S6K) and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells.
Experimental neurology 20070101
-
mTOR pathway as a target in tissue hypertrophy.
Annual review of pharmacology and toxicology 20070101
-
In silico prediction of pregnane X receptor activators by machine learning approaches.
Molecular pharmacology 20070101
-
Determination of everolimus in whole blood using the Abbott IMx sirolimus microparticle enzyme immunoassay.
Clinical biochemistry 20070101
-
The pharmacodynamic effects of sirolimus and sirolimus-calcineurin inhibitor combinations on macrophage scavenger and nuclear hormone receptors.
Journal of pharmaceutical sciences 20070101
-
Inhibition of restenosis development after mechanical injury: a new field of application for malononitrilamides?
Cardiology 20070101
-
Constitutive activation of mTOR signaling pathway in post-transplant lymphoproliferative disorders.
Laboratory investigation; a journal of technical methods and pathology 20070101
-
Mycophenolate acid inhibits endothelial NAD(P)H oxidase activity and superoxide formation by a Rac1-dependent mechanism.
Hypertension (Dallas, Tex. : 1979) 20070101
-
A current problem in cardiology: very late thrombosis after implantation of sirolimus eluting stent.
Cardiology 20070101
-
Persistent donor-specific alloreactivity may portend delayed liver rejection during drug minimization in children.
Frontiers in bioscience : a journal and virtual library 20070101
-
The long-term value of sirolimus- and paclitaxel-eluting stents over bare metal stents in patients with diabetes mellitus.
European heart journal 20070101
-
Epithelial-mesenchymal interactions in keloid pathogenesis modulate vascular endothelial growth factor expression and secretion.
The Journal of pathology 20070101
-
Concurrent implantation of sirolimus- and paclitaxel-eluting stents in the same vessel.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070101
-
Intracoronary radiation therapy for multi-drug resistant in-stent restenosis: initial clinical experience.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070101
-
First-in-human implantation of a fully bioabsorbable drug-eluting stent: the BVS poly-L-lactic acid everolimus-eluting coronary stent.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070101
-
Incidence and predictors of recurrent restenosis following implantation of drug-eluting stents for in-stent restenosis.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070101
-
Two-year clinical outcome after coronary stenting of small vessels using 2.25-mm sirolimus- and paclitaxel-eluting stents: insight into the RESEARCH and T-SEARCH registries.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070101
-
Everolimus is a potent inducer of erythroid differentiation and gamma-globin gene expression in human erythroid cells.
Acta haematologica 20070101
-
Total synthesis of rapamycin.
Angewandte Chemie (International ed. in English) 20070101
-
Response of U87 glioma xenografts treated with concurrent rapamycin and fractionated radiotherapy: possible role for thrombosis.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20070101
-
Sirolimus-associated desquamative interstitial pneumonia.
Respiration; international review of thoracic diseases 20070101
-
Drug-eluting stents: preventing restenosis.
Cardiology in review 20070101
-
Shining a light on protein expression in living organisms.
Nature chemical biology 20070101
-
Drug-eluting stents for the treatment of bifurcation lesions: a randomized comparison between paclitaxel and sirolimus stents.
American heart journal 20070101
-
No robust conclusions to be drawn from clinical trials in the absence of an adequate control group.
Transplant international : official journal of the European Society for Organ Transplantation 20070101
-
12-month safety and efficacy of everolimus with reduced exposure cyclosporine in de novo renal transplant recipients.
Transplant international : official journal of the European Society for Organ Transplantation 20070101
-
Selective survival of naturally occurring human CD4+CD25+Foxp3+ regulatory T cells cultured with rapamycin.
Journal of immunology (Baltimore, Md. : 1950) 20070101
-
Success rate of implantation and mid-term outcomes of the sirolimus-eluting stent.
Circulation journal : official journal of the Japanese Circulation Society 20070101
-
XIENCE V everolimus-eluting coronary stent system: a novel second generation drug-eluting stent.
Expert review of medical devices 20070101
-
Sirolimus promotes tolerance for donor and recipient antigens after MHC class II disparate bone marrow transplantation in rats.
Experimental hematology 20070101
-
Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin.
The American journal of pathology 20070101
-
Phosphatase targets in TOR signaling.
Methods in molecular biology (Clifton, N.J.) 20070101
-
Effect of rapamycin on hepatocyte function and proliferation induced by growth factors.
Chemotherapy 20070101
-
Everolimus-induced mTOR inhibition selectively depletes macrophages in atherosclerotic plaques by autophagy.
Autophagy 20070101
-
Sirolimus improves early microcirculation, but impairs regeneration after pancreatic ischemia-reperfusion injury.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070101
-
Changes in renal function after clinical islet transplantation: four-year observational study.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070101
-
Very late restenosis of a sirolimus-eluting stent after left main coronary artery stenting.
The Canadian journal of cardiology 20070101
-
Rapamycin as an inhibitor of osteogenic differentiation in bone marrow-derived mesenchymal stem cells.
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20070101
-
Chronic allograft nephropathy score before sirolimus rescue predicts allograft function in renal transplant patients.
Transplantation proceedings 20070101
-
Four cases of sirolimus-associated interstitial pneumonitis: identification of risk factors.
Transplantation proceedings 20070101
-
New immunosuppresor strategies in the treatment of murine lupus nephritis.
Lupus 20070101
-
[Hemolytic uremic syndrome due to sirolimus in a heart transplant recipient. Case report].
Revista espanola de cardiologia 20070101
-
Drug-eluting stent implantation in ST-elevation acute myocardial infarction: 'real world' 30-day and mid-term results.
Cardiovascular revascularization medicine : including molecular interventions 20070101
-
The ups and downs of sirolimus in kidney transplantation, and the importance of reporting negative findings.
The Netherlands journal of medicine 20070101
-
Inferior results with basis immunosuppression with sirolimus in kidney transplantation.
The Netherlands journal of medicine 20070101
-
Drug-eluting stent implantation in bifurcated lesions with balloon-crushing technique and 6 fr guiding catheter: immediate and mid-term results.
The Journal of invasive cardiology 20070101
-
Treatment of a double-bifurcation lesion with sirolimus-eluting stents using the 'sleeve technique'.
The Journal of invasive cardiology 20070101
-
Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance.
Molecular cancer 20070101
-
How to treat recurrences of in-stent restenosis?
Internal medicine (Tokyo, Japan) 20070101
-
Early steroid withdrawal therapy in renal transplant recipients: a steroid-free sirolimus and CellCept-based calcineurin inhibitor-minimization protocol.
Clinical transplantation 20070101
-
The novel mTOR inhibitor RAD001 (everolimus) induces antiproliferative effects in human pancreatic neuroendocrine tumor cells.
Neuroendocrinology 20070101
-
New therapeutics for soft-tissue sarcomas in adults.
Oncology (Williston Park, N.Y.) 20070101
-
Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice.
Respiratory research 20070101
-
Use of sirolimus in solid organ transplantation.
Drugs 20070101
-
[Percutaneous coronary intervention for the elderly patients].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20070101
-
Newly approved therapies for RCC and their effect on the standard of care.
Clinical advances in hematology & oncology : H&O 20070101
-
A novel immunosuppressive agent, sirolimus, in the treatment of Kaposi's sarcoma in a renal transplant recipient.
Renal failure 20070101
-
Do the benefits outweigh the risks with drug-eluting stents?
Scandinavian cardiovascular journal : SCJ 20070101
-
Amino acids and insulin act additively to regulate components of the ubiquitin-proteasome pathway in C2C12 myotubes.
BMC molecular biology 20070101
-
Angioedema in renal transplant recipients on sirolimus.
Dermatology (Basel, Switzerland) 20070101
-
CCI-779 plus cisplatin is highly effective against human melanoma in a SCID mouse xenotranplantation model.
Pharmacology 20070101
-
A potential screening tool for IPEX syndrome.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 20070101
-
Angiographic and clinical outcome following sirolimus-eluting stent (Cypher) implantation. A single center experience.
International heart journal 20070101
-
Molecularly targeted therapy for Kaposi's sarcoma in a kidney transplant patient: case report, 'what worked and what did not'.
BMC nephrology 20070101
-
[Late localized aneurysmal dilations after sirolimus-eluting stents in 4 patients].
Zhonghua xin xue guan bing za zhi 20070101
-
Incidence of late stent thrombosis with bare-metal, sirolimus, and paclitaxel stents.
Reviews in cardiovascular medicine 20070101
-
Rapamycin-induced inhibition of HTLV-I LTR activity is rescued by c-Myb.
Retrovirology 20070101
-
[Stents in interventional cardiology].
Medicina (Kaunas, Lithuania) 20070101
-
Control of apoptosis in human multiple myeloma by insulin-like growth factor I (IGF-I).
Advances in cancer research 20070101
-
Mechanisms of TSC-mediated control of synapse assembly and axon guidance.
PloS one 20070101
-
Manipulating regulatory T cells.
Cytotherapy 20070101
-
Rapamycin enriches for CD4(+) CD25(+) CD27(+) Foxp3(+) regulatory T cells in ex vivo-expanded CD25-enriched products from healthy donors and patients with multiple sclerosis.
Cytotherapy 20070101
-
[Pro- and antitumor effects of the main immunosuppressive drugs used in the clinical practice of transplantation].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20070101
-
Calcineurin inhibitor substitution with sirolimus vs. reduced-dose calcineurin inhibitor plus sirolimus is associated with improved renal dysfunction in heart transplant patients.
Clinical transplantation 20070101
-
Factors influencing glomerular filtration rate in renal transplantation after cyclosporine withdrawal using sirolimus-based therapy: a multivariate analysis of results at five years.
Clinical transplantation 20070101
-
Effects of sirolimus vs. calcineurin inhibitors on renal dysfunction after orthotopic liver transplantation.
Clinical transplantation 20070101
-
Sirolimus inhibits key events of restenosis in vitro/ex vivo: evaluation of the clinical relevance of the data by SI/MPL- and SI/DES-ratios.
BMC cardiovascular disorders 20070101
-
The next generation of drug-eluting stents: what's on the horizon?
American journal of cardiovascular drugs : drugs, devices, and other interventions 20070101
-
Rapamycin for treatment of refractory dysthyroid compressive optic neuropathy.
Ophthalmic plastic and reconstructive surgery 20070101
-
Engineering aspects of stents design and their translation into clinical practice.
Annali dell'Istituto superiore di sanita 20070101
-
Surgical wound-healing complications in heart transplant recipients treated with rapamycin.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20070101
-
Saccharomyces cerevisiae FKBP12 binds Arabidopsis thaliana TOR and its expression in plants leads to rapamycin susceptibility.
BMC plant biology 20070101
-
Immunosuppression on the horizon.
Heart failure clinics 20070101
-
When is retransplantation a viable option?
Heart failure clinics 20070101
-
Advanced renal cell carcinoma: current and emerging management strategies.
Drugs 20070101
-
Neointimal hyperplasia persists at six months after sirolimus-eluting stent implantation in diabetic porcine.
Cardiovascular diabetology 20070101
-
The making of a queen: TOR pathway is a key player in diphenic caste development.
PloS one 20070101
-
Effects of rapamycin on active Heymann nephritis.
American journal of nephrology 20070101
-
Successful surgical treatment of an infected right coronary artery aneurysm-to-right ventricle fistula after sirolimus-eluting stent implantation.
Internal medicine (Tokyo, Japan) 20070101
-
mTOR inhibitors (rapamycin and its derivatives) and nitrogen containing bisphosphonates: bi-functional compounds for the treatment of bone tumours.
Current medicinal chemistry 20070101
-
The search for endothelium friendly stents.
Medical device technology 20070101
-
Regulation of hepatic oval cell proliferation by adenoviral mediated hepatocyte growth factor gene transfer and signal transduction inhibitors.
Hepato-gastroenterology 20070101
-
Everolimus retards cyst growth and preserves kidney function in a rodent model for polycystic kidney disease.
Kidney & blood pressure research 20070101
-
Roles of mTOR and STAT3 in autophagy induced by telomere 3' overhang-specific DNA oligonucleotides.
Autophagy 20070101
-
The role of targeted therapy in metastatic renal cell carcinoma.
TheScientificWorldJournal 20070101
-
Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death.
Autophagy 20070101
-
Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy.
Molecular cancer 20070101
-
Risk factors for impaired wound healing in sirolimus-treated renal transplant recipients.
Clinical transplantation 20070101
-
Sirolimus exposure during the early post-transplant period reduces the risk of CMV infection relative to tacrolimus in renal allograft recipients.
Clinical transplantation 20070101
-
Clinical outcomes of renal transplant recipients treated with enteric-coated mycophenolic acid vs. mycophenolate mofetil as a switch agent using a primary steroid-free rapamune and microemulsion cyclosporine protocol.
Clinical transplantation 20070101
-
Comparison of sirolimus and everolimus in their effects on blood lipid profiles and haematological parameters in heart transplant recipients.
Clinical transplantation 20070101
-
[Effect of angiogenesis inhibitors on renal cell carcinoma].
Magyar onkologia 20070101
-
Immunosuppression for lung transplantation: evidence to date.
Drugs 20070101
-
Rapamycin prevents early steps of the development of diabetic nephropathy in rats.
American journal of nephrology 20070101
-
Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin module for acute myelogenous leukemia therapy: from bench to bedside.
Current medicinal chemistry 20070101
-
Higher incidence of acute rejection in renal transplant recipients with low everolimus exposure.
Transplantation proceedings 20070101
-
Sirolimus monotherapy in liver transplantation.
Transplantation proceedings 20070101
-
Possible role of everolimus in improving renal function in long-term heart transplantation.
Transplantation proceedings 20070101
-
Conversion to rapamycin immunosuppression for malignancy after kidney transplantation: case reports.
Transplantation proceedings 20070101
-
Peritoneal leiomyosarcoma in a kidney transplant patient: a case report.
Transplantation proceedings 20070101
-
Everolimus and mycophenolate mofetil sensitize human pancreatic cancer cells to gemcitabine in vitro: a novel adjunct to standard chemotherapy?
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20070101
-
T-cell function monitoring in stable renal transplant patients treated with sirolimus monotherapy.
Molecular diagnosis & therapy 20070101
-
Roles of cytokines in the pathogenesis and therapy of type 1 diabetes.
Cell biochemistry and biophysics 20070101
-
Small molecule enhancers of rapamycin-induced TOR inhibition promote autophagy, reduce toxicity in Huntington's disease models and enhance killing of mycobacteria by macrophages.
Autophagy 20070101
-
Immunoassay determination of rapamycin: reliability of the method with respect to liquid chromatography mass spectrometric quantification.
Clinical transplantation 20070101
-
The use of sirolimus in ganciclovir-resistant cytomegalovirus infections in renal transplant recipients.
Clinical transplantation 20070101
-
Promising new targeted agents in head and neck cancer.
International journal of radiation oncology, biology, physics 20070101
-
New drugs: ambrisentan, temsirolimus, and eculizumab.
Journal of the American Pharmacists Association : JAPhA 20070101
-
Clinical proof-of-concept trial to assess the therapeutic effect of sirolimus in patients with autosomal dominant polycystic kidney disease: SUISSE ADPKD study.
BMC nephrology 20070101
-
Prevention of murine lupus disease in (NZBxNZW)F1 mice by sirolimus treatment.
Lupus 20070101
-
Hematopoietic stem cell transplantation across major genetic barriers.
Immunologic research 20070101
-
Molecule of the month. Temsirolimus.
Drug news & perspectives 20070101
-
Effects of controlled-released sirolimus from polymer matrices on human coronary artery smooth muscle cells.
Journal of biomaterials science. Polymer edition 20070101
-
[Angiogenesis targeting in renal carcinomas].
Bulletin du cancer 20070101
-
RAD inhibition of sarcoma growth: implications for laryngeal transplantation.
American journal of otolaryngology 20070101
-
Tuberous sclerosis preclinical studies: timing of treatment, combination of a rapamycin analog (CCI-779) and interferon-gamma, and comparison of rapamycin to CCI-779.
BMC pharmacology 20070101
-
Coupled down-regulation of mTOR and telomerase activity during fluorouracil-induced apoptosis of hepatocarcinoma cells.
BMC cancer 20070101
-
[Clinical implications of coronary stents coated with drugs].
Terapevticheskii arkhiv 20070101
-
[Lymphangioleiomyomatosis and translational medicine].
Medicina 20070101
-
Development of an ultra-performance liquid chromatography technique coupled with mass spectrometry for the measurement of tacrolimus in micro-samples of whole blood, and its application on a pharmacokiinetic trial.
Arzneimittel-Forschung 20070101
-
Clinical use of sirolimus-eluting stents.
Cardiovascular drug reviews 20070101
-
Transcriptome of angiopoietin 1-activated human umbilical vein endothelial cells.
Endothelium : journal of endothelial cell research 20070101
-
Conditional transgenesis using Dimerizable Cre (DiCre).
PloS one 20070101
-
Unprotected left main coronary artery intervention for acute myocardial infarction and cardiogenic shock.
Texas Heart Institute journal 20070101
-
Rapamycin enhances the anti-tumor effect of gemcitabine in pancreatic cancer cells.
Hepato-gastroenterology 20070101
-
[Revascularization of the myocardium in patients with ischemic heart disease. Experience of the use of sirolimus eluting stents].
Kardiologiia 20070101
-
[Drug-eluting stent thrombosis and its pharmacological prevention].
Kardiologiia 20070101
-
[An experience of the use of stents with drug coating in patients with long and diffuse coronary artery lesions].
Kardiologiia 20070101
-
One-sided limb lymphedema in a liver transplant recipient receiving sirolimus.
Acta gastro-enterologica Belgica 20070101
-
[Glioblastomas are resistant to apoptosis but less resistant to the autophagic process].
Bulletin et memoires de l'Academie royale de medecine de Belgique 20070101
-
[Sirolimus: mechanism of action, use in combined chemotherapy of cancer].
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20070101
-
Delayed stent fracture and aneurysm formation after sirolimus eluting stent.
Indian heart journal 20070101
-
Pathology of drug-eluting stents: implications for coronary intervention.
Indian heart journal 20070101
-
Taxus vs. Cypher: making sense of the 'evidence-based' data.
Indian heart journal 20070101
-
Newer stents: looking at the horizon.
Indian heart journal 20070101
-
Diabetic multivessel disease: stenting vs. coronary artery bypass grafting.
Indian heart journal 20070101
-
Revascularizing diabetics: the CARDia trial.
Indian heart journal 20070101
-
Pregnancy outcomes in solid organ transplant recipients with exposure to mycophenolate mofetil or sirolimus.
Transplantation 20061227
-
Conversion to sirolimus in renal transplant recipients with skin cancer.
Transplantation 20061227
-
Comparative analysis of calcineurin inhibition by complexes of immunosuppressive drugs with human FK506 binding proteins.
Biochemistry 20061226
-
Combination treatment of low dose Anti-Thymocyte Globulin (ATG), Rituximab and high dose Sirolimus as induction agents in immune-conditioned recipients.
International immunopharmacology 20061220
-
Affects of immunosuppression on circulating dendritic cells: an adjunct to therapeutic drug monitoring after heart transplantation.
International immunopharmacology 20061220
-
Reccurence of Kaposi's sarcoma after increased exposure to sirolimus.
International immunopharmacology 20061220
-
Randomized double-blind comparison of sirolimus-eluting stent versus bare-metal stent implantation in diseased saphenous vein grafts: six-month angiographic, intravascular ultrasound, and clinical follow-up of the RRISC Trial.
Journal of the American College of Cardiology 20061219
-
Comparison of zotarolimus-eluting and sirolimus-eluting stents in patients with native coronary artery disease: a randomized controlled trial.
Journal of the American College of Cardiology 20061219
-
Late clinical events after clopidogrel discontinuation may limit the benefit of drug-eluting stents: an observational study of drug-eluting versus bare-metal stents.
Journal of the American College of Cardiology 20061219
-
Drug eluting stents.
BMJ (Clinical research ed.) 20061216
-
Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients.
Journal of immunology (Baltimore, Md. : 1950) 20061215
-
Volumetric intravascular ultrasound assessment of neointimal hyperplasia and nonuniform stent strut distribution in sirolimus-eluting stent restenosis.
The American journal of cardiology 20061215
-
Comparison of clinical outcomes of overlapping sirolimus- versus paclitaxel-eluting stents in patients undergoing percutaneous coronary intervention.
The American journal of cardiology 20061215
-
Everolimus interferes with healing of experimental intestinal anastomoses.
Transplantation 20061215
-
Targeting von Hippel-Lindau pathway in renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20061215
-
Translational control via the mammalian target of rapamycin pathway is critical for the formation and stability of long-term fear memory in amygdala neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20061213
-
Targeted therapy for metastatic renal cell carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061210
-
Saccharomyces cerevisiae Sit4 phosphatase is active irrespective of the nitrogen source provided, and Gln3 phosphorylation levels become nitrogen source-responsive in a sit4-deleted strain.
The Journal of biological chemistry 20061208
-
Drug-eluting stents in primary PCI.
The New England journal of medicine 20061207
-
Drug-eluting stents in primary PCI.
The New England journal of medicine 20061207
-
Drug-eluting stents in primary PCI.
The New England journal of medicine 20061207
-
Rapamycin decreases leukocyte migration in vivo and effectively reduces experimentally induced chronic colitis.
International journal of colorectal disease 20061201
-
Sirolimus accelerates senescence of endothelial progenitor cells through telomerase inactivation.
Atherosclerosis 20061201
-
Requirement of androgen-dependent activation of protein kinase Czeta for androgen-dependent cell proliferation in LNCaP Cells and its roles in transition to androgen-independent cells.
Molecular endocrinology (Baltimore, Md.) 20061201
-
Everolimus drug interactions: application of a classification system for clinical decision making.
Biopharmaceutics & drug disposition 20061201
-
Microwave expedited synthesis of 5-aminocamptothecin analogs: Inhibitors of hypoxia inducible factor HIF-1alpha.
Bioorganic & medicinal chemistry letters 20061201
-
Rapid chemically induced changes of PtdIns(4,5)P2 gate KCNQ ion channels.
Science (New York, N.Y.) 20061201
-
Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling.
The Journal of biological chemistry 20061201
-
Helicobacter pylori VacA toxin inhibits human immunodeficiency virus infection of primary human T cells.
Journal of virology 20061201
-
Mortality in randomized controlled trials comparing drug-eluting vs. bare metal stents in coronary artery disease: a meta-analysis.
European heart journal 20061201
-
Low-dose oral rapamycin treatment reduces fibrogenesis, improves liver function, and prolongs survival in rats with established liver cirrhosis.
Journal of hepatology 20061201
-
Comparison of the Innofluor certican assay with HPLC-UV for the determination of everolimus concentrations in heart transplantation.
Clinical biochemistry 20061201
-
Differential effects of immunosuppressive drugs on T-cell motility.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20061201
-
Blocking of Akt/NF-kappaB signaling by pentoxifylline inhibits platelet-derived growth factor-stimulated proliferation in Brown Norway rat airway smooth muscle cells.
Pediatric research 20061201
-
Sirolimus as the main immunosuppressant in the early postoperative period following liver transplantation: a report of six cases and review of the literature.
Transplant international : official journal of the European Society for Organ Transplantation 20061201
-
Sirolimus-eluting stents and calcified coronary lesions: clinical outcomes of patients treated with and without rotational atherectomy.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20061201
-
Sirolimus pharmacokinetic differences between children and adults.
Pediatric transplantation 20061201
-
Sirolimus pharmacokinetics in pediatric renal transplant recipients receiving calcineurin inhibitor co-therapy.
Pediatric transplantation 20061201
-
Premature discontinuation of antiplatelet therapy in patients with drug-eluting coronary stents.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20061201
-
Cypher versus Taxus: the stent war.
Expert opinion on investigational drugs 20061201
-
Cause of death with bare metal and sirolimus-eluting stents.
European heart journal 20061201
-
Increased mortality after implantation of first generation drug-eluting stents: seeing the smoke, where is the fire?
European heart journal 20061201
-
Cost-effectiveness of the unrestricted use of sirolimus-eluting stents vs. bare metal stents at 1 and 2-year follow-up: results from the RESEARCH Registry.
European heart journal 20061201
-
Drug-eluting stents and stent thrombosis: a cause for concern?
Coronary artery disease 20061201
-
Late stent thrombosis in drug-eluting stents: return of the 'VB syndrome'.
Nature clinical practice. Cardiovascular medicine 20061201
-
Drug-eluting stent thrombosis: it's never too late.
Nature clinical practice. Cardiovascular medicine 20061201
-
Revascularization of left anterior descending artery with drug-eluting stents: comparison with minimally invasive direct coronary artery bypass surgery.
The Annals of thoracic surgery 20061201
-
Comparison with conventional therapies of repeated sirolimus-eluting stent implantation for the treatment of drug-eluting coronary stent restenosis.
The American journal of cardiology 20061201
-
Safety and efficacy of the 2.25-mm sirolimus-eluting Bx Velocity stent in the treatment of patients with de novo native coronary artery lesions: the SIRIUS 2.25 trial.
The American journal of cardiology 20061201
-
Comparison of the efficacy of direct coronary stenting with sirolimus-eluting stents versus stenting with predilation by intravascular ultrasound imaging (from the DIRECT trial).
The American journal of cardiology 20061201
-
Conversion to sirolimus: a useful strategy for recalcitrant cutaneous viral warts in liver transplant recipient.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20061201
-
Rapamycin-mediated inhibition of mammalian target of rapamycin in skeletal muscle cells reduces glucose utilization and increases fatty acid oxidation.
Metabolism: clinical and experimental 20061201
-
Brief review: coronary drug-eluting stents and anesthesia.
Canadian journal of anaesthesia = Journal canadien d'anesthesie 20061201
-
Late thrombosis of drug-eluting stents: a meta-analysis of randomized clinical trials.
The American journal of medicine 20061201
-
The evolving impact of microfabrication and nanotechnology on stent design.
Journal of vascular surgery 20061201
-
Lipid oxidation and autophagy in yeast.
Free radical biology & medicine 20061201
-
Targeting the AIB1 oncogene through mammalian target of rapamycin inhibition in the mammary gland.
Cancer research 20061201
-
Drug-eluting and bare nitinol stents for the treatment of atherosclerotic lesions in the superficial femoral artery: long-term results from the SIROCCO trial.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20061201
-
Comparison of sirolimus-eluting and bare metal stents in coronary bifurcation lesions: subgroup analysis of the Stenting Coronary Arteries in Non-Stress/Benestent Disease Trial (SCANDSTENT).
American heart journal 20061201
-
Predictors of death or myocardial infarction during follow-up after coronary stenting with the sirolimus-eluting stent. Results from the prospective multicenter German Cypher Stent Registry.
American heart journal 20061201
-
Angioscopic evaluation of neointima coverage: sirolimus drug-eluting stent versus bare metal stent.
American heart journal 20061201
-
The role of therapeutic drug monitoring in individualizing immunosuppressive drug therapy: recent developments.
Therapeutic drug monitoring 20061201
-
12-hour area under the curve cyclosporine concentrations determined by a validated liquid chromatography-mass spectrometry procedure compared with fluorescence polarization immunoassay reveals sirolimus effect on cyclosporine pharmacokinetics.
Therapeutic drug monitoring 20061201
-
[The role of caspase-3 in rapamycin-induced apoptosis of hepatocellular carcinoma BEL-7402 cells].
Ai zheng = Aizheng = Chinese journal of cancer 20061201
-
Farnesyltransferase inhibitors and rapamycin in the treatment of multiple myeloma.
Current pharmaceutical biotechnology 20061201
-
Plumbagin induces G2-M arrest and autophagy by inhibiting the AKT/mammalian target of rapamycin pathway in breast cancer cells.
Molecular cancer therapeutics 20061201
-
Changes in abdominal wounds following treatment with sirolimus and steroids in a rat model.
Transplantation proceedings 20061201
-
Differential pharmacokinetic interaction of tacrolimus and cyclosporine on everolimus.
Transplantation proceedings 20061201
-
Short-term results under three different immunosuppressive regimens at one center.
Transplantation proceedings 20061201
-
Results of a calcineurin-inhibitor-free immunosuppressive protocol in renal transplant recipients of expanded criteria deceased donors.
Transplantation proceedings 20061201
-
Sirolimus attenuates the rate of progression of early chronic allograft nephropathy.
Transplantation proceedings 20061201
-
Proteinuria after conversion to sirolimus in renal transplant recipients.
Transplantation proceedings 20061201
-
Post-rapamycin proteinuria: incidence, evolution, and therapeutic handling at a single center.
Transplantation proceedings 20061201
-
Exposure-efficacy relationships of a fingolimod-everolimus regimen in kidney transplant patients at risk for delayed graft function.
Transplantation proceedings 20061201
-
Risk factors for wound healing complications in sirolimus-treated renal transplant recipients.
Transplantation proceedings 20061201
-
Characteristics of neoplasm occurrence and the therapeutic effect of sirolimus in South Chinese kidney transplant recipients.
Transplantation proceedings 20061201
-
Predictors of decline in renal function after lung transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20061201
-
Molecularly targeted therapy in renal cell carcinoma: where do we go from here?
Expert review of anticancer therapy 20061201
-
Targeted therapies in metastatic renal cell carcinoma: the light at the end of the tunnel.
Expert review of anticancer therapy 20061201
-
Effects of sirolimus on proteinuria and renal function in focal segmental glomerulonephritis.
International journal of clinical pharmacology and therapeutics 20061201
-
Successful mobilization of peripheral blood stem cells by use of granulocyte-colony stimulating factor and their transcoronary transplantation in a patient after cardiogenic shock due to acute myocardial infarction.
The Journal of invasive cardiology 20061201
-
Late stent thrombosis mimicking focal restenosis after sirolimus stent implantation: angiographic and intravascular ultrasound appraisal.
The Journal of invasive cardiology 20061201
-
[Pulmonary toxicity associated with sirolimus therapy in liver transplantation].
Gastroenterologia y hepatologia 20061201
-
Apparent clearance of sirolimus in heart transplant recipients: impact of primary diagnosis and serum lipids.
Therapeutic drug monitoring 20061201
-
Effects of tacrolimus or sirolimus on proliferation of vascular smooth muscle and endothelial cells.
Journal of cardiovascular pharmacology 20061201
-
Temporal decline in sirolimus elimination immediately after pancreatic islet transplantation.
Drug metabolism and pharmacokinetics 20061201
-
Renal function and histology in kidney transplant patients receiving tacrolimus and sirolimus or mycophenolate mofetil.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20061201
-
[Initial and mid-term effects of > or = 30 mm long sirolimus-eluting stents in patients with diffuse long coronary lesions: comparison with bare metal stents].
Journal of cardiology 20061201
-
The growing role of mTOR in neuronal development and plasticity.
Molecular neurobiology 20061201
-
[The clinical efficacy of sirolimus-eluting stents versus paclitaxel-eluting stents in complex and diffuse coronary lesions].
Zhonghua nei ke za zhi 20061201
-
Effect of rapamycin on the fate of P23H opsin associated with retinitis pigmentosa (an American Ophthalmological Society thesis).
Transactions of the American Ophthalmological Society 20061201
-
The influence of copolymer chain microstructure on cyclosporine a (CyA) and Sirolimus prolonged and sustained release from PLA/TMC and PLA/PCL matrices.
Journal of controlled release : official journal of the Controlled Release Society 20061128
-
Use of the organotypic culture method to investigate drug-loaded CSF shunt.
Journal of controlled release : official journal of the Controlled Release Society 20061128
-
Ethoxyethyl methacrylate-based copolymers--a novel platform for drug-eluting stent coatings.
Journal of controlled release : official journal of the Controlled Release Society 20061128
-
Generating rapamycin analogues by directed biosynthesis: starter acid substrate specificity of mono-substituted cyclohexane carboxylic acids.
Organic & biomolecular chemistry 20061121
-
Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin.
Blood 20061115
-
Conversion from calcineurin inhibitors to sirolimus for chronic renal allograft dysfunction: a systematic review of the evidence.
Transplantation 20061115
-
Combined transcriptional and translational targeting of EWS/FLI-1 in Ewing's sarcoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20061115
-
Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20061115
-
Early- and medium-term outcomes after paclitaxel-eluting stent implantation for sirolimus-eluting stent failure.
The American journal of cardiology 20061115
-
Outcomes of 6906 patients undergoing percutaneous coronary intervention in the era of drug-eluting stents: report of the DEScover Registry.
Circulation 20061114
-
Sirolimus-eluting stent versus paclitaxel-eluting stent for patients with long coronary artery disease.
Circulation 20061114
-
Images in cardiovascular medicine. Damage to polymer of a sirolimus-eluting stent.
Circulation 20061114
-
Recurrent restenosis in a patient with cardiac allograft vasculopathy: after angioplasty and sirolimus, paclitaxel saves the day.
International journal of cardiology 20061110
-
Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways.
Oncogene 20061109
-
Trading restenosis for thrombosis? New questions about drug-eluting stents.
The New England journal of medicine 20061109
-
Connecting the dots using gene-expression profiles.
The New England journal of medicine 20061109
-
A phase II clinical and pharmacodynamic study of temsirolimus in advanced neuroendocrine carcinomas.
British journal of cancer 20061106
-
Modulation of collagen and MMP-1 gene expression in fibroblasts by the immunosuppressive drug rapamycin. A direct role as an antifibrotic agent?
The Journal of biological chemistry 20061103
-
Targeting survivin via PI3K but not c-akt/PKB by anticancer drugs in immature neutrophils.
Oncogene 20061102
-
Safety, tolerability, and efficacy of everolimus in de novo liver transplant recipients: 12- and 36-month results.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20061101
-
Regression of post-transplant Kaposi's sarcoma using sirolimus.
International journal of clinical practice 20061101
-
Inclusion of MPA and in a rapid multi-drug LC-tandem mass spectrometric method for simultaneous determination of immunosuppressants.
Clinica chimica acta; international journal of clinical chemistry 20061101
-
Controlled release of sirolimus from a multilayered PLGA stent matrix.
Biomaterials 20061101
-
A downstream kinase of the mammalian target of rapamycin, p70S6K1, regulates human double minute 2 protein phosphorylation and stability.
Journal of cellular physiology 20061101
-
Use of a stringent dimerizer-regulated gene expression system for controlled BMP2 delivery.
Molecular therapy : the journal of the American Society of Gene Therapy 20061101
-
Cyclosporine withdrawal improves renal function in heart transplant patients on reduced-dose cyclosporine therapy.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20061101
-
Effects of rapamycin on accumulation of alpha-, beta- and gamma-globin mRNAs in erythroid precursor cells from beta-thalassaemia patients.
European journal of haematology 20061101
-
Increase of proteinuria after conversion from calcineurin inhibitor to sirolimus-based treatment in kidney transplant patients with chronic allograft dysfunction.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20061101
-
The immunosuppressant rapamycin exacerbates neurotoxicity of Abeta peptide.
Journal of neuroscience research 20061101
-
Nitrogen availability and TOR regulate the Snf1 protein kinase in Saccharomyces cerevisiae.
Eukaryotic cell 20061101
-
Antiangiogenic and immunomodulatory effects of rapamycin on islet endothelium: relevance for islet transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20061101
-
PTEN in the haematopoietic system and its therapeutic indications.
Trends in molecular medicine 20061101
-
The role of heme oxygenase 1 in rapamycin-induced renal dysfunction after ischemia and reperfusion injury.
Kidney international 20061101
-
Outcomes at 3 years of a prospective pilot study of Campath-1H and sirolimus immunosuppression for renal transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20061101
-
Outcome in the real-world of coronary high-risk intervention with drug-eluting stents (ORCHID) -- a single-center study comparing Cypher sirolimus-eluting with Taxus paclitaxel-eluting stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20061101
-
Randomized trial versus registry data--comparing apples and ORCHIDs.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20061101
-
Stent thrombosis following the STAR technique in a complex RCA chronic total occlusion.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20061101
-
Sirolimus for below the knee lesions: mid-term results of SiroBTK study.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20061101
-
Surfactant as a carrier: influence of immunosuppressive agents on surfactant activity.
Clinical physiology and functional imaging 20061101
-
Chemotherapy disrupts activity of translational regulatory proteins in bone marrow stromal cells.
Experimental hematology 20061101
-
Risk of noncardiac surgery after coronary drug-eluting stent implantation.
The American journal of cardiology 20061101
-
Inflammatory response to drug-eluting stent placement.
The American journal of cardiology 20061101
-
Everolimus and mTOR inhibitors in liver transplantation: opening the 'box'.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20061101
-
Clinical and angiographic outcomes of sirolimus-eluting stents implantation in Japanese patients in daily practice.
Circulation journal : official journal of the Japanese Circulation Society 20061101
-
Persistent malapposition after implantation of sirolimus-eluting stent into intramural coronary hematoma: optical coherence tomography observations.
Circulation journal : official journal of the Japanese Circulation Society 20061101
-
Drug-eluting stents in total coronary occlusions: another piece of the puzzle solved?
American heart journal 20061101
-
Sirolimus versus bare metal stent implantation in patients with total coronary occlusions: subgroup analysis of the Stenting Coronary Arteries in Non-Stress/Benestent Disease (SCANDSTENT) trial.
American heart journal 20061101
-
Single-vessel versus bifurcation stenting for the treatment of distal left main coronary artery disease in the drug-eluting stenting era. Clinical and angiographic insights into the Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) and Taxus-Stent Evaluated at Rotterdam Cardiology Hospital (T-SEARCH) registries.
American heart journal 20061101
-
Comparison between drug-eluting stents and beta-radiation for the treatment of diffuse in-stent restenosis: clinical and angiographic outcomes.
American heart journal 20061101
-
Progressive stent technologies: new approaches for the treatment of cardiovascular diseases.
Expert opinion on drug delivery 20061101
-
Critics say drug-eluting stents overused.
JAMA 20061101
-
Use of sirolimus for Epstein-Barr virus-positive smooth-muscle tumour.
The Lancet. Oncology 20061101
-
Should the left main be covered entirely with drug-eluting stents in percutaneous intervention.
The Journal of invasive cardiology 20061101
-
Incomplete stent apposition in a left main bifurcated lesion after kissing stent implantation.
The Journal of invasive cardiology 20061101
-
Protein kinases as drug targets in cancer.
Current cancer drug targets 20061101
-
Use of sirolimus to facilitate steroid withdrawal from a cyclosporine regimen.
Transplantation proceedings 20061101
-
Initial single-center experience with sirolimus after lung transplantation.
Transplantation proceedings 20061101
-
A monoselective sphingosine-1-phosphate receptor-1 agonist prevents allograft rejection in a stringent rat heart transplantation model.
Chemistry & biology 20061101
-
Dissecting the mechanism of T-cell anergy with immunophilin ligands.
Current opinion in investigational drugs (London, England : 2000) 20061101
-
Rapamycin synergizes with the epidermal growth factor receptor inhibitor erlotinib in non-small-cell lung, pancreatic, colon, and breast tumors.
Molecular cancer therapeutics 20061101
-
Drug-eluting stents--safety concerns.
Clinical cardiology 20061101
-
[Promising efficacy of the sirolimus-eluting stent in patients with acute myocardial infarction].
Journal of cardiology 20061101
-
[Update on clinical activity of CCI779 (temsirolimus), mTOR inhibitor].
Bulletin du cancer 20061101
-
Case report: sirolimus associated interstitial lung disease.
South Dakota medicine : the journal of the South Dakota State Medical Association 20061101
-
Late outcome of sirolimus-eluting stents: comparison of multidetector computed tomography with quantitative coronary angiography and intravascular ultrasound.
Arquivos brasileiros de cardiologia 20061101
-
Very late stent thrombosis after implantation of drug eluting stent.
The Journal of the Association of Physicians of India 20061101
-
BioMatrix Biolimus A9-eluting coronary stent: a next-generation drug-eluting stent for coronary artery disease.
Expert review of medical devices 20061101
-
[Safety and efficacy comparison between rapamycin-eluting stent with biodegradable polymer or permanent polymer in patients with coronary artery disease].
Zhonghua xin xue guan bing za zhi 20061101
-
[Sirolimus inhibits the differentiation, proliferation and migration of endothelial progenitor cells in vitro].
Zhonghua xin xue guan bing za zhi 20061101
-
Beyond imatinib: second generation c-KIT inhibitors for the management of gastrointestinal stromal tumors.
Clinical colorectal cancer 20061101
-
Randomized study on simple versus complex stenting of coronary artery bifurcation lesions: the Nordic bifurcation study.
Circulation 20061031
-
[Drug-eluting coronary stents].
Orvosi hetilap 20061029
-
Images in cardiovascular medicine. Hypertrophic obstructive cardiomyopathy: septal ablation with overlapping sirolimus-eluting and covered stents after failed alcoholization and concomitant coronary artery disease.
Circulation 20061024
-
Predicted mechanisms of resistance to mTOR inhibitors.
British journal of cancer 20061023
-
Sirolimus-eluting stents vs brachytherapy for restenosis.
JAMA 20061018
-
[Administration of sirolimus affects vein graft neointima hyperplasia].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20061018
-
Unprotected left main disease: stent or surgery?
Journal of the American College of Cardiology 20061017
-
mTOR and cancer therapy.
Oncogene 20061016
-
Effect of plaque volume on subsequent vessel remodeling at edges of sirolimus-eluting stents.
The American journal of cardiology 20061015
-
Sirolimus interferes with iron homeostasis in renal transplant recipients.
Transplantation 20061015
-
Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells.
Cancer research 20061015
-
Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling.
Oncogene 20061012
-
Switch from cyclosporine to sirolimus as a treatment of acute renal failure complicating cardiogenic shock in a heart transplant recipient.
International journal of cardiology 20061010
-
Rapamycin biosynthesis: Elucidation of gene product function.
Organic & biomolecular chemistry 20061007
-
Activity- and mTOR-dependent suppression of Kv1.1 channel mRNA translation in dendrites.
Science (New York, N.Y.) 20061006
-
Vessel size and outcome after coronary drug-eluting stent placement: results from a large cohort of patients treated with sirolimus- or paclitaxel-eluting stents.
Journal of the American College of Cardiology 20061003
-
All drug-eluting stents are equal, but some drug-eluting stents are more equal than others.
Journal of the American College of Cardiology 20061003
-
Clinical outcomes for sirolimus-eluting stents and polymer-coated paclitaxel-eluting stents in daily practice: results from a large multicenter registry.
Journal of the American College of Cardiology 20061003
-
Citrus auraptene targets translation of MMP-7 (matrilysin) via ERK1/2-dependent and mTOR-independent mechanism.
FEBS letters 20061002
-
Recurrence of proteinuria 10 years post-transplant in NPHS2-associated focal segmental glomerulosclerosis after conversion from cyclosporin A to sirolimus.
Pediatric nephrology (Berlin, Germany) 20061001
-
Mammalian target of rapamycin regulates the growth of mammary epithelial cells through the inhibitor of deoxyribonucleic acid binding Id1 and their functional differentiation through Id2.
Molecular endocrinology (Baltimore, Md.) 20061001
-
Combination of a rapamycin analog (CCI-779) and interferon-gamma is more effective than single agents in treating a mouse model of tuberous sclerosis complex.
Genes, chromosomes & cancer 20061001
-
Everolimus inhibits glomerular endothelial cell proliferation and VEGF, but not long-term recovery in experimental thrombotic microangiopathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20061001
-
Registry data evaluating the effectiveness of drug-eluting stents for the treatment of symptomatic in-stent restenosis.
Heart, lung & circulation 20061001
-
The impact of the mTOR inhibitor sirolimus on the proliferation and function of pancreatic islets and ductal cells.
Diabetologia 20061001
-
Proteinuria following conversion from azathioprine to sirolimus in renal transplant recipients.
Kidney international 20061001
-
The proangiogenic phenotype of human tumor-derived endothelial cells depends on thrombospondin-1 downregulation via phosphatidylinositol 3-kinase/Akt pathway.
Journal of molecular medicine (Berlin, Germany) 20061001
-
Patterns of restenosis after drug-eluting stent implantation: Insights from a contemporary and comparative analysis of sirolimus- and paclitaxel-eluting stents.
European heart journal 20061001
-
Calcineurin-inhibitor induced pain syndrome after organ transplantation.
Kidney international 20061001
-
Safety, feasibility, and short-term follow-up of drug-eluting stent placement in the intracranial and extracranial circulation.
Stroke 20061001
-
Effect of rapamycin on renal ischemia-reperfusion injury in mice.
Transplant international : official journal of the European Society for Organ Transplantation 20061001
-
Sirolimus monotherapy versus sirolimus in combination with steroids and/or MMF for immunosuppression after liver transplantation.
Digestive diseases and sciences 20061001
-
Investigating mammalian target of rapamycin inhibitors for their anticancer properties.
Expert opinion on investigational drugs 20061001
-
A Bayesian approach for population pharmacokinetic modelling of sirolimus.
British journal of clinical pharmacology 20061001
-
A comparison of the effect of ciclosporin and sirolimus on the pharmokinetics of mycophenolate in renal transplant patients.
British journal of clinical pharmacology 20061001
-
Three-year clinical follow-up of the unrestricted use of sirolimus-eluting stents as part of the Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry.
The American journal of cardiology 20061001
-
Clinical and angiographic outcomes after placement of multiple overlapping drug-eluting stents in diffuse coronary lesions.
The American journal of cardiology 20061001
-
Monomorphic Epstein-Barr virus (EBV)-associated large B-cell posttransplant lymphoproliferative disorder presenting as a tongue ulcer in a pancreatic transplant patient.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20061001
-
Mycophenolate mofetil versus sirolimus as an adjunct to calcineurin inhibition after renal transplantation.
Nature clinical practice. Nephrology 20061001
-
Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance.
Cancer cell 20061001
-
Sirolimus monotherapy for Kaposi's sarcoma in an HIV-negative patient.
The Lancet. Oncology 20061001
-
Autophagy in cancer: good, bad, or both?
Cancer research 20061001
-
Ras-induced modulation of CXCL10 and its receptor splice variant CXCR3-B in MDA-MB-435 and MCF-7 cells: relevance for the development of human breast cancer.
Cancer research 20061001
-
Clinical evidence on polymer-based sirolimus and paclitaxel eluting stents.
Minerva cardioangiologica 20061001
-
How to treat diabetic patients with multivesseal disease in the DES era.
Minerva cardioangiologica 20061001
-
Overview of pharmacology and clinical trials program with the zotarolimus-eluting endeavor stent.
Journal of interventional cardiology 20061001
-
A phase I and pharmacokinetic study of temsirolimus (CCI-779) administered intravenously daily for 5 days every 2 weeks to patients with advanced cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 20061001
-
Role of the Fusarium fujikuroi TOR kinase in nitrogen regulation and secondary metabolism.
Eukaryotic cell 20061001
-
A temporal switch in the insulin-signalling pathway that regulates hepatic IGF-binding protein-1 gene expression.
Journal of molecular endocrinology 20061001
-
Sirolimus--challenging current perspectives.
Therapeutic drug monitoring 20061001
-
Apparent clearance of sirolimus in heart transplant recipients: impact of primary diagnosis and serum lipids.
Therapeutic drug monitoring 20061001
-
Safety and pharmacokinetics of sirolimus-eluting stents in the canine cerebral vasculature: 180 day assessment.
Neurosurgery 20061001
-
Signaling interactions of rapamycin combined with erlotinib in cervical carcinoma xenografts.
Molecular cancer therapeutics 20061001
-
The antitumor effects of sunitinib (formerly SU11248) against a variety of human hematologic malignancies: enhancement of growth inhibition via inhibition of mammalian target of rapamycin signaling.
Molecular cancer therapeutics 20061001
-
Balloon alignment T-stenting for bifurcation coronary artery disease using the sirolimus-eluting stent.
The Journal of invasive cardiology 20061001
-
Sirolimus-eluting stenting of the external carotid artery for the treatment of ocular ischemia.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20061001
-
Iliac anastomotic stenting with a sirolimus-eluting biodegradable poly-L-lactide stent: a preliminary study after 6 weeks.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20061001
-
Molecular biology of renal cell carcinoma.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20061001
-
Mammalian target of rapamycin inhibitors in combination with letrozole in breast cancer.
Clinical breast cancer 20061001
-
Calcineurin inhibitors affect circulating regulatory T cells in stable renal transplant recipients.
Transplantation proceedings 20061001
-
Conversion to everolimus in kidney transplant recipients: a safe and simple procedure.
Transplantation proceedings 20061001
-
Pulmonary toxicity associated with sirolimus treatment in kidney transplantation.
Transplantation proceedings 20061001
-
Conversion to sirolimus in renal transplant patients with tumors.
Transplantation proceedings 20061001
-
Conversion from calcineurin inhibitors to everolimus in kidney transplant recipients with malignant neoplasia.
Transplantation proceedings 20061001
-
Sirolimus experience in heart transplantation.
Transplantation proceedings 20061001
-
Sirolimus attenuates chronic allograft nephropathy in an experimental rat kidney transplantation model.
Transplantation proceedings 20061001
-
[Efficacy of sirolimus-eluting stent implantation in diabetic patients with very small vessels (< or = 2.25 mm). Insights from the DIABETES trial].
Revista espanola de cardiologia 20061001
-
Living donor islet transplantation, the alternative approach to overcome the obstacles limiting transplant.
Annals of the New York Academy of Sciences 20061001
-
Direct versus predilatation drug-eluting stenting: a randomized clinical trial.
The Journal of invasive cardiology 20061001
-
Generation of HSP60-specific regulatory T cell and effect on atherosclerosis.
Cellular immunology 20061001
-
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.
Science (New York, N.Y.) 20060929
-
Rapamycin and dendritic cells: keep on movin'.
Transplantation 20060927
-
Development of de novo cancer in p53 knock-out mice is dependent on the type of long-term immunosuppression used.
Transplantation 20060927
-
Differential effects of immunosuppressive drugs on chemokine receptor CCR7 in human monocyte-derived dendritic cells: selective upregulation by rapamycin.
Transplantation 20060927
-
mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s.
Current biology : CB 20060919
-
Human cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexes.
Proceedings of the National Academy of Sciences of the United States of America 20060919
-
Characterization of plaque prolapse after drug-eluting stent implantation in diabetic patients: a three-dimensional volumetric intravascular ultrasound outcome study.
Journal of the American College of Cardiology 20060919
-
Rapamycin improves lymphoproliferative disease in murine autoimmune lymphoproliferative syndrome (ALPS).
Blood 20060915
-
Comparison of outcomes between bare metal stents and drug-eluting stents for percutaneous revascularization of internal mammary grafts.
The American journal of cardiology 20060915
-
Acute renal failure following kidney transplantation associated with myoglobinuria in patients treated with rapamycin.
Transplantation 20060915
-
Sirolimus-eluting versus uncoated stents in acute myocardial infarction.
The New England journal of medicine 20060914
-
Drug-eluting stents in acute myocardial infarction.
The New England journal of medicine 20060914
-
Release of anti-restenosis drugs from poly(ethylene oxide)-poly(DL-lactic-co-glycolic acid) nanoparticles.
Journal of controlled release : official journal of the Controlled Release Society 20060912
-
Inhibition of mammalian target of rapamycin modulates expression of adhesion molecules in endothelial cells.
Toxicology letters 20060910
-
Targeting protein stability with a small molecule.
Cell 20060908
-
Mind the GAP: Wnt steps onto the mTORC1 train.
Cell 20060908
-
TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth.
Cell 20060908
-
Three new drugs available to fight kidney cancer.
Journal of the National Cancer Institute 20060906
-
Cyclosporin A, tacrolimus and sirolimus are potent inhibitors of the human breast cancer resistance protein (ABCG2) and reverse resistance to mitoxantrone and topotecan.
Cancer chemotherapy and pharmacology 20060901
-
Leucine in food mediates some of the postprandial rise in plasma leptin concentrations.
American journal of physiology. Endocrinology and metabolism 20060901
-
Fibroblasts isolated from human pterygia exhibit altered lipid metabolism characteristics.
Experimental eye research 20060901
-
Co-administration of sirolimus alters tacrolimus pharmacokinetics in a dose-dependent manner in adult renal transplant recipients.
Pharmacological research 20060901
-
Sirolimus conversion for patients with posttransplant Kaposi's sarcoma.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060901
-
mTOR inhibition induces endothelial progenitor cell death.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060901
-
Rheb inhibits C-raf activity and B-raf/C-raf heterodimerization.
The Journal of biological chemistry 20060901
-
Prolongation of allograft survival by administration of anti-CD45RB monoclonal antibody is due to alteration of CD45RBhi: CD45RBlo T-cell proportions.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060901
-
Role of P-glycoprotein in cyclosporine cytotoxicity in the cyclosporine-sirolimus interaction.
Kidney international 20060901
-
['HAART-attack' in young female HIV-patient].
Der Internist 20060901
-
Effect of sirolimus in the prevention of adhesions around intraabdominal prosthetic graft.
World journal of surgery 20060901
-
Mammalian target of rapamycin inhibition induces cell cycle arrest in diffuse large B cell lymphoma (DLBCL) cells and sensitises DLBCL cells to rituximab.
British journal of haematology 20060901
-
The place of sirolimus in kidney transplantation: can we reduce calcineurin inhibitor renal toxicity?
Kidney international 20060901
-
Akt and Mammalian target of rapamycin regulate separate systems of proteolysis in renal tubular cells.
Journal of the American Society of Nephrology : JASN 20060901
-
Improved survival with drug-eluting stent implantation in comparison with bare metal stent in patients with severe left ventricular dysfunction.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060901
-
Very late [corrected] thrombosis of a sirolimus-eluting stent.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060901
-
The role of BMS in the drug eluting stent era: is still there any place for them?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060901
-
Angioscopic differences in neointimal coverage and in persistence of thrombus between sirolimus-eluting stents and bare metal stents after a 6-month implantation.
European heart journal 20060901
-
Rapamycin induces regression of endometriotic lesions by inhibiting neovascularization and cell proliferation.
British journal of pharmacology 20060901
-
Delayed neointimal healing after drug-eluting stent implantation: seeing is believing.
European heart journal 20060901
-
New treatment approaches in metastatic renal cell carcinoma.
Current opinion in urology 20060901
-
Treatment strategies in pediatric solid organ transplant recipients with calcineurin inhibitor-induced nephrotoxicity.
Pediatric transplantation 20060901
-
Amiodarone-sirolimus/tacrolimus interaction in a pediatric heart transplant patient.
Pediatric transplantation 20060901
-
Effect of SU11248 on gastrointestinal stromal tumor-T1 cells: enhancement of growth inhibition via inhibition of 3-kinase/Akt/mammalian target of rapamycin signaling.
Cancer science 20060901
-
Ex vivo rapamycin generates Th1/Tc1 or Th2/Tc2 Effector T cells with enhanced in vivo function and differential sensitivity to post-transplant rapamycin therapy.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20060901
-
Relation of C-reactive protein level and long-term risk of death or myocardial infarction following percutaneous coronary intervention with a sirolimus-eluting stent.
The American journal of cardiology 20060901
-
Investigating the caffeine effects in the yeast Saccharomyces cerevisiae brings new insights into the connection between TOR, PKC and Ras/cAMP signalling pathways.
Molecular microbiology 20060901
-
Mycophenolate mofetil and sirolimus combination in renal transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060901
-
Antitumoral activity of rapamycin in renal angiomyolipoma associated with tuberous sclerosis complex.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20060901
-
Sirolimus is associated with reduced islet engraftment and impaired beta-cell function.
Diabetes 20060901
-
Constitutive phosphorylation of the S6 ribosomal protein via mTOR and ERK signaling in the peripheral blasts of acute leukemia patients.
Experimental hematology 20060901
-
Rapamycin reduces disease activity and normalizes T cell activation-induced calcium fluxing in patients with systemic lupus erythematosus.
Arthritis and rheumatism 20060901
-
[Effect of rapamycin and dexamethasone on differentiation and maturation of murine bone marrow-derived dendritic cells].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20060901
-
Phase I/II study of the mammalian target of rapamycin inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 20060901
-
Natural Products in Drug Discovery & Development II--2nd annual Taylor & Francis conference. 21-22 June 2006, London, UK.
IDrugs : the investigational drugs journal 20060901
-
Drug evaluation: AP-23573--an mTOR inhibitor for the treatment of cancer.
IDrugs : the investigational drugs journal 20060901
-
Combination therapy for treating breast cancer using antiestrogen, ERA-923, and the mammalian target of rapamycin inhibitor, temsirolimus.
Endocrine-related cancer 20060901
-
Sirolimus-associated interstitial pneumonitis in 3 heart transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060901
-
[Nephrotoxicity of sirolimus: experimental and clinical data].
Nephrologie & therapeutique 20060901
-
Therapeutic targets: MTOR and related pathways.
Cancer biology & therapy 20060901
-
Influence of everolimus on cyclosporine Neoral pharmacokinetics in Chinese de novo cardiac transplant recipients.
Transplantation proceedings 20060901
-
Therapeutic drug monitoring of cyclosporine Neoral in de novo Chinese cardiac transplant recipients treated with an everolimus-cyclosporine immunosuppressive regimen.
Transplantation proceedings 20060901
-
Comparison of rapamycin versus FK506 on expression of cytoprotective genes in the rat kidney allografts undergoing chronic allograft nephropathy.
Transplantation proceedings 20060901
-
Evaluation of an immunoassay (Abbott-IMX Analyzer) allowing routine determination of sirolimus: comparison with LC-MS method.
Transplantation proceedings 20060901
-
Phosphatidylinositol 3-kinase/Akt plays a part in tumor necrosis factor-alpha-induced interleukin-6 synthesis in osteoblasts.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20060901
-
Cyclin D3 is down-regulated by rapamycin in HER-2-overexpressing breast cancer cells.
Molecular cancer therapeutics 20060901
-
Aging and immortality: quasi-programmed senescence and its pharmacologic inhibition.
Cell cycle (Georgetown, Tex.) 20060901
-
Use of APO2L/TRAIL with mTOR inhibitors in the treatment of glioblastoma multiforme.
Expert review of anticancer therapy 20060901
-
Stenting of unprotected left main coronary artery in patients with low preoperative risk of coronary artery bypass grafting.
Kardiologia polska 20060901
-
Effectiveness of a sirolimus-eluting stent (Cypher) for diffuse in-stent restenosis inside a bare metal stent.
International heart journal 20060901
-
Late angiographic stent thrombosis in a drug-eluting stent that occurred 20 months after premature discontinuation of clopidogrel administration.
International heart journal 20060901
-
Revascularization of malignant coronary instent restenosis resulting from Takayasu's arteritis using sirolimus-eluting stents.
International heart journal 20060901
-
The Akt/mTOR and mitogen-activated protein kinase pathways in lung cancer therapy.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20060901
-
Steroid sparing in kidney transplantation: changing paradigms, improving outcomes, and remaining questions.
Clinical journal of the American Society of Nephrology : CJASN 20060901
-
Sirolimus therapy following early cyclosporine withdrawal in transplant patients: mechanisms of action and clinical results.
International journal of nanomedicine 20060901
-
Current status of clinical trials for glioblastoma.
Reviews on recent clinical trials 20060901
-
Nutrient regulates Tor1 nuclear localization and association with rDNA promoter.
Nature 20060831
-
Primary Stenting of Totally Occluded Native Coronary Arteries II (PRISON II): a randomized comparison of bare metal stent implantation with sirolimus-eluting stent implantation for the treatment of total coronary occlusions.
Circulation 20060829
-
The FRB domain of mTOR: NMR solution structure and inhibitor design.
Biochemistry 20060829
-
Tacrolimus and sirolimus cause insulin resistance in normal sprague dawley rats.
Transplantation 20060827
-
Calcineurin inhibitors, but not rapamycin, reduce percentages of CD4+CD25+FOXP3+ regulatory T cells in renal transplant recipients.
Transplantation 20060827
-
TOR regulates late steps of ribosome maturation in the nucleoplasm via Nog1 in response to nutrients.
The EMBO journal 20060823
-
Randomized, double-blind, multicenter study of the Endeavor zotarolimus-eluting phosphorylcholine-encapsulated stent for treatment of native coronary artery lesions: clinical and angiographic results of the ENDEAVOR II trial.
Circulation 20060822
-
Letter by Tsai et al regarding article, 'correlates and long-term outcomes of angiographically proven stent thrombosis with sirolimus- and Paclitaxel-eluting stents'.
Circulation 20060822
-
PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR.
Nature 20060817
-
A developmental transition in growth control during zebrafish caudal fin development.
Developmental biology 20060815
-
Outcome after acute incomplete sirolimus-eluting stent apposition as assessed by serial intravascular ultrasound.
The American journal of cardiology 20060815
-
Angiographic results of the first human experience with the Biolimus A9 drug-eluting stent for de novo coronary lesions.
The American journal of cardiology 20060815
-
Effect of everolimus-eluting stents in different vessel sizes (from the pooled FUTURE I and II trials).
The American journal of cardiology 20060815
-
Differences in proteinuria and graft function in de novo sirolimus-based vs. calcineurin inhibitor-based immunosuppression in live donor kidney transplantation.
Transplantation 20060815
-
Delayed gastric ulcer healing associated with sirolimus.
Transplantation 20060815
-
Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells.
Cancer research 20060815
-
Patency of the left coronary artery by 64-slice multislice computed tomography following implantation of sirolimus-eluting stent.
International journal of cardiology 20060810
-
Rapamycin activates Tap42-associated phosphatases by abrogating their association with Tor complex 1.
The EMBO journal 20060809
-
Spatial memory formation and memory-enhancing effect of glucose involves activation of the tuberous sclerosis complex-Mammalian target of rapamycin pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20060802
-
Effects of a combined treatment with mTOR inhibitor RAD001 and tamoxifen in vitro on growth and apoptosis of human cancer cells.
Gynecologic oncology 20060801
-
Neointimal proliferation around malapposed struts of a sirolimus-eluting stent: optical coherence tomography findings.
European heart journal 20060801
-
Switching immunosuppression medications after renal transplantation--a common practice.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060801
-
Rapamycin inhibits growth and survival of D816V-mutated c-kit mast cells.
Blood 20060801
-
Hypoxia-inducible factor-1-dependent and -independent regulation of insulin-like growth factor-1-stimulated vascular endothelial growth factor secretion.
The Journal of pharmacology and experimental therapeutics 20060801
-
Nephrotoxicity of ciclosporin A: short-term gain, long-term pain?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060801
-
Rapamycin confers preconditioning-like protection against ischemia-reperfusion injury in isolated mouse heart and cardiomyocytes.
Journal of molecular and cellular cardiology 20060801
-
Rapamycin (sirolimus): a two-edged sword?
Journal of molecular and cellular cardiology 20060801
-
Characterisation of the lung toxicity of the cell cycle inhibitor temsirolimus.
European journal of cancer (Oxford, England : 1990) 20060801
-
Vascularization and engraftment of a human skin substitute using circulating progenitor cell-derived endothelial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060801
-
Chronic inhibition of mammalian target of rapamycin signaling downregulates insulin receptor substrates 1 and 2 and AKT activation: A crossroad between cancer and diabetes?
Journal of the American Society of Nephrology : JASN 20060801
-
Long-term effects of novel biolimus eluting DEVAX AXXESS plus nitinol self-expanding stent in a porcine coronary model.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060801
-
Oral sirolimus after bare metal stent implantation.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060801
-
Evaluation of the haemodynamic characteristics of drug-eluting stents at implantation and at follow-up.
European heart journal 20060801
-
Post-transplant de novo malignancies in renal transplant recipients: the past and present.
Transplant international : official journal of the European Society for Organ Transplantation 20060801
-
Complementary effects of sirolimus-eluting stents and glycoprotein IIb/IIIa inhibitors for percutaneous coronary intervention in diabetic patients: one-year follow up of a single-centre registry.
Heart (British Cardiac Society) 20060801
-
Conversion from calcineurin inhibitor to sirolimus in pediatric chronic allograft nephropathy.
Pediatric transplantation 20060801
-
SRL-based immunosuppression vs. CNI minimization in pediatric renal transplant recipients with chronic CNI nephrotoxicity.
Pediatric transplantation 20060801
-
Comparison of bare metal stents versus drug-eluting stents on clinical decision making in patients with previous percutaneous coronary intervention admitted for suspected acute coronary syndrome.
The American journal of cardiology 20060801
-
Frequency of and risk factors for stent thrombosis after drug-eluting stent implantation during long-term follow-up.
The American journal of cardiology 20060801
-
Impact of sirolimus-eluting and Paclitaxel-eluting stents on outcome in patients with diabetes mellitus and stenting in more than one coronary artery.
The American journal of cardiology 20060801
-
Neointima inhibition: comparison of effectiveness of non-stent-based local drug delivery and a drug-eluting stent in porcine coronary arteries.
Radiology 20060801
-
Documented subacute stent thrombosis within thirty days after stenting with sirolimus-eluting stent (Cypher) for acute myocardial infarction: a Japanese single center retrospective non-randomized study.
Circulation journal : official journal of the Japanese Circulation Society 20060801
-
Immunosuppression using the mTOR inhibition mechanism affects replacement of rat liver with transplanted cells.
Hepatology (Baltimore, Md.) 20060801
-
Everolimus alters imatinib blood partition in favour of the erythrocyte.
The Journal of pharmacy and pharmacology 20060801
-
Sustained intraocular rapamycin delivery effectively prevents high-risk corneal allograft rejection and neovascularization in rabbits.
Investigative ophthalmology & visual science 20060801
-
Frequency and determinants of black holes in sirolimus-eluting stent restenosis.
The Journal of invasive cardiology 20060801
-
Inhibition of mTOR reduces chronic pressure-overload cardiac hypertrophy and fibrosis.
Journal of hypertension 20060801
-
Identification of direct and indirect targets of the Gln3 and Gat1 activators by transcriptional profiling in response to nitrogen availability in the short and long term.
FEMS yeast research 20060801
-
Sirolimus-eluting stent in chronic total occlusion: the SICTO study.
Journal of interventional cardiology 20060801
-
Clinical and angiographic follow-up after coronary drug-eluting and bare metal stent implantation. Do drug-eluting stents hold the promise?
Journal of internal medicine 20060801
-
Late-onset invasive aspergillosis in organ transplant recipients in the current era.
Medical mycology 20060801
-
Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo.
Cancer research 20060801
-
Sensitive, high throughput HPLC-MS/MS method with on-line sample clean-up for everolimus measurement.
Therapeutic drug monitoring 20060801
-
Proteomic analysis of anti-angiogenic effects by a combined treatment with vinblastine and rapamycin in an endothelial cell line.
Proteomics 20060801
-
Reverse diastolic intrarenal flow due to calcineurin inhibitor (CNI) toxicity.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060801
-
Prolactin activates mammalian target-of-rapamycin through phosphatidylinositol 3-kinase and stimulates phosphorylation of p70S6K and 4E-binding protein-1 in lymphoma cells.
The Journal of endocrinology 20060801
-
An in vivo platform for translational drug development in pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 20060801
-
Intracellular signaling in tumor and endothelial cells: The expected and, yet again, the unexpected.
Cancer cell 20060801
-
The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor.
Cancer cell 20060801
-
Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin.
Cancer cell 20060801
-
New hope for RCC patients.
European journal of cancer (Oxford, England : 1990) 20060801
-
Alleviation of renal and pulmonary injury by immunomodulation in leptospirosis: hamster model.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20060801
-
Thyroid hormone stimulates protein synthesis in the cardiomyocyte by activating the Akt-mTOR and p70S6K pathways.
The Journal of biological chemistry 20060728
-
Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting.
World journal of gastroenterology 20060728
-
Cost analysis from two randomized trials of sirolimus-eluting stents versus paclitaxel-eluting stents in high-risk patients with coronary artery disease.
Journal of the American College of Cardiology 20060718
-
Effectiveness and safety of sirolimus stent implantation for coronary in-stent restenosis: the TRUE (Tuscany Registry of Sirolimus for Unselected In-Stent Restenosis) Registry.
Journal of the American College of Cardiology 20060718
-
Rapamycin-mediated enrichment of T cells with regulatory activity in stimulated CD4+ T cell cultures is not due to the selective expansion of naturally occurring regulatory T cells but to the induction of regulatory functions in conventional CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 20060715
-
Sirolimus-eluting stents versus Paclitaxel-eluting stents in the treatment of coronary artery disease in patients with diabetes mellitus.
The American journal of cardiology 20060715
-
Rapamycin delays but does not prevent recovery from acute renal failure: role of acquired tubular resistance.
Transplantation 20060715
-
Stimulation of the intestinal phosphate transporter SLC34A2 by the protein kinase mTOR.
Biochemical and biophysical research communications 20060714
-
Trials probe new agents for kidney cancer.
JAMA 20060712
-
A comparison of angiographic and clinical outcomes after sirolimus-eluting versus paclitaxel-eluting stents for the treatment of in-stent restenosis.
Chinese medical journal 20060705
-
Periprocedural and late consequences of overlapping Cypher sirolimus-eluting stents: pooled analysis of five clinical trials.
Journal of the American College of Cardiology 20060704
-
Rapid decline of collateral circulation increases susceptibility to myocardial ischemia: the trade-off of successful percutaneous recanalization of chronic total occlusions.
Journal of the American College of Cardiology 20060704
-
Pathology of drug-eluting stents in humans: delayed healing and late thrombotic risk.
Journal of the American College of Cardiology 20060704
-
Drug-eluting stent thrombosis: increasingly recognized but too frequently overemphasized.
Journal of the American College of Cardiology 20060704
-
Role of endothelin-1 and nitric oxide bioavailability in transplant-related vascular injury: comparative effects of rapamycin and cyclosporine.
Circulation 20060704
-
Post-transplantation anaemia in adult and paediatric renal allograft recipients-Guy's Hospital experience.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701
-
Bioluminescence imaging after HSV amplicon vector delivery into brain.
The journal of gene medicine 20060701
-
Podospora anserina target of rapamycin.
Current genetics 20060701
-
Comparative effects of paclitaxel and rapamycin on smooth muscle migration and survival: role of AKT-dependent signaling.
Arteriosclerosis, thrombosis, and vascular biology 20060701
-
Query Chem: a Google-powered web search combining text and chemical structures.
Bioinformatics (Oxford, England) 20060701
-
A patient recently transplanted with a living donor kidney develops severe neurological symptoms.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701
-
Mammalian target of rapamycin inhibitors in sarcomas.
Current opinion in oncology 20060701
-
Evaluation of a fluorescent polarization immunoassay for whole blood everolimus determination using samples from renal transplant recipients.
Clinical biochemistry 20060701
-
Conversion from calcineurin inhibitor to sirolimus for renal function deterioration in kidney allograft recipients.
Archives of medical research 20060701
-
alpha-lipoic acid regulates AMP-activated protein kinase and inhibits insulin secretion from beta cells.
Diabetologia 20060701
-
Impact of three or more sirolimus-eluting stents versus paclitaxel-eluting stents on clinical outcomes in patients undergoing percutaneous coronary intervention.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060701
-
Experimental efficacy of an everolimus eluting cobalt chromium stent.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060701
-
Very late thrombosis after drug-eluting stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060701
-
Effects of tacrolimus, cyclosporin A and sirolimus on MG63 cells.
Transplant international : official journal of the European Society for Organ Transplantation 20060701
-
Sudden hearing loss associated with tacrolimus in a liver transplant recipient.
Transplant international : official journal of the European Society for Organ Transplantation 20060701
-
Acne in recipients of renal transplantation treated with sirolimus: clinical, microbiologic, histologic, therapeutic, and pathogenic aspects.
Journal of the American Academy of Dermatology 20060701
-
Sirolimus-eluting stents at two years: a pooled analysis of SIRIUS, E-SIRIUS, and C-SIRIUS with emphasis on late revascularizations and stent thromboses.
The American journal of cardiology 20060701
-
Effects of cyclosporin A, FK506 and rapamycin on calcineurin phosphatase activity in mouse brain.
IUBMB life 20060701
-
Everolimus: an immunosuppressive agent in transplantation.
Expert opinion on pharmacotherapy 20060701
-
Risk factors for impaired health status differ in women and men treated with percutaneous coronary intervention in the drug-eluting stent era.
Journal of psychosomatic research 20060701
-
CYP3A5*3 influences sirolimus oral clearance in de novo and stable renal transplant recipients.
Clinical pharmacology and therapeutics 20060701
-
Potential role of proliferation signal inhibitors on atherosclerosis in renal transplant patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701
-
Everolimus in clinical practice--renal transplantation.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701
-
Conversion to everolimus in maintenance patients--current clinical strategies.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701
-
Conversion to a proliferation signal inhibitor in a patient with coronary artery disease--a case report.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701
-
Conversion to everolimus in a patient with arterial hypertension and recurrent cutaneous neoplasia--a case report.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701
-
Long-term cardiovascular risk in transplantation--insights from the use of everolimus in heart transplantation.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701
-
Sirolimus-induced pneumonitis presenting as acute respiratory distress syndrome.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060701
-
Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.
Cancer research 20060701
-
Tacrolimus and sirolimus: when bad things happen to good drugs.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060701
-
Long-term renal allograft function on a tacrolimus-based, pred-free maintenance immunosuppression comparing sirolimus vs. MMF.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060701
-
Regulation of mTOR by mechanically induced signaling events in skeletal muscle.
Cell cycle (Georgetown, Tex.) 20060701
-
Inhibition of the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway in hematologic malignancies.
Current treatment options in oncology 20060701
-
Coronary artery restenosis: vascular biology and emerging therapeutic strategies.
Expert review of cardiovascular therapy 20060701
-
[Inhibition of growth and metastasis of hepatocellular carcinoma by rapamycin: experiment with mice].
Zhonghua yi xue za zhi 20060627
-
[Local applied slow-releasing rapamycin inhibits neointima hyperplasia in vein graft].
Zhonghua yi xue za zhi 20060627
-
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity.
The EMBO journal 20060621
-
PTEN takes center stage in cancer stem cell research, works as tumor suppressor.
Journal of the National Cancer Institute 20060621
-
Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: results from the PREMIER registry.
Circulation 20060620
-
Drug-eluting stent restenosis the pattern predicts the outcome.
Journal of the American College of Cardiology 20060620
-
Narrative review: drug-eluting stents for the management of restenosis: a critical appraisal of the evidence.
Annals of internal medicine 20060620
-
A role for the mTOR pathway in surface expression of AMPA receptors.
Neuroscience letters 20060619
-
Activation of the mTOR signalling pathway is required for pancreatic growth in protease-inhibitor-fed mice.
The Journal of physiology 20060615
-
Images in cardiovascular medicine. Severe endothelial dysfunction after sirolimus-eluting stent implantation.
Circulation 20060613
-
[Diffuse lung diseases].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20060610
-
General repression of RNA polymerase III transcription is triggered by protein phosphatase type 2A-mediated dephosphorylation of Maf1.
Molecular cell 20060609
-
Evaluation of rapamycin chemical stability in volatile-organic solvents by HPLC.
Journal of pharmaceutical and biomedical analysis 20060607
-
A randomized comparison of sirolimus-eluting stent with balloon angioplasty in patients with in-stent restenosis: results of the Restenosis Intrastent: Balloon Angioplasty Versus Elective Sirolimus-Eluting Stenting (RIBS-II) trial.
Journal of the American College of Cardiology 20060606
-
Vascular effects of sirolimus-eluting versus bare-metal stents in diabetic patients: three-dimensional ultrasound results of the Diabetes and Sirolimus-Eluting Stent (DIABETES) Trial.
Journal of the American College of Cardiology 20060606
-
Zotarolimus (ABT-578) eluting stents.
Advanced drug delivery reviews 20060603
-
Clinical experience and applications of drug-eluting stents in the noncoronary vasculature, bile duct and esophagus.
Advanced drug delivery reviews 20060603
-
Countervailing effects of rapamycin (sirolimus) on nuclear factor-kappa B activities in neointimal and medial smooth muscle cells.
Atherosclerosis 20060601
-
Sirolimus-eluting stent fracture with thrombus, visualization by optical coherence tomography.
European heart journal 20060601
-
Insulin-facilitated increase of muscle protein synthesis after resistance exercise involves a MAP kinase pathway.
American journal of physiology. Endocrinology and metabolism 20060601
-
Rapamycin antagonizes NF-kappaB nuclear translocation activated by TNF-alpha in primary vascular smooth muscle cells and enhances apoptosis.
American journal of physiology. Heart and circulatory physiology 20060601
-
Increase in S6K1 phosphorylation in human skeletal muscle following resistance exercise occurs mainly in type II muscle fibers.
American journal of physiology. Endocrinology and metabolism 20060601
-
Insulin and oxidative stress modulate proliferation of rat ovarian theca-interstitial cells through diverse signal transduction pathways.
Biology of reproduction 20060601
-
Effect of severe short-term malnutrition on diaphragm muscle signal transduction pathways influencing protein turnover.
Journal of applied physiology (Bethesda, Md. : 1985) 20060601
-
Bifurcation stenting with drug eluting stents: illustration of the crush technique.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060601
-
Intravascular ultrasound predictors of angiographic restenosis after sirolimus-eluting stent implantation.
European heart journal 20060601
-
'Head-to-head comparison between sirolimus-eluting and paclitaxel-eluting stents in patients with complex coronary artery disease: an intravascular ultrasound study'.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060601
-
Rapamycin induces a caspase-independent cell death in human monocytes.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060601
-
Tacrolimus with mycophenolate mofetil (MMF) or sirolimus vs. cyclosporine with MMF in cardiac transplant patients: 1-year report.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060601
-
Everolimus and reduced cyclosporine trough levels in maintenance heart transplant recipients.
Transplant immunology 20060601
-
Recent developments in targeting the mammalian target of rapamycin (mTOR) kinase pathway.
Anti-cancer drugs 20060601
-
Conversion from calcineurin inhibitor to sirolimus in pediatric chronic allograft nephropathy.
Pediatric transplantation 20060601
-
Rapamycin, an mTOR inhibitor, disrupts triglyceride metabolism in guinea pigs.
Metabolism: clinical and experimental 20060601
-
Very late thrombosis after sirolimus-eluting stent implantation.
Journal of cardiovascular medicine (Hagerstown, Md.) 20060601
-
A meta-analysis of trials comparing Cypher and Taxus stents in patients with obstructive coronary artery disease.
British journal of clinical pharmacology 20060601
-
Rapamycin and chronic kidney disease: beyond the inhibition of inflammation.
Kidney international 20060601
-
The fate of patients with clinical recurrence after sirolimus-eluting stent implantation (a two-year follow-up analysis from the SIRIUS trial).
The American journal of cardiology 20060601
-
Overcoming T cell-mediated rejection of bone marrow allografts by T-regulatory cells: synergism with veto cells and rapamycin.
Experimental hematology 20060601
-
The incidence of acute cellular rejection after lung transplantation: a comparative study of anti-thymocyte globulin and daclizumab.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060601
-
Sirolimus for Kaposi's sarcoma.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060601
-
Induction of tolerance in type 1 diabetes via both CD4+CD25+ T regulatory cells and T regulatory type 1 cells.
Diabetes 20060601
-
Rapamycin attenuates unilateral ureteral obstruction-induced renal fibrosis.
Kidney international 20060601
-
Antiangiogenic potential of the Mammalian target of rapamycin inhibitor temsirolimus.
Cancer research 20060601
-
Perspectives in central nervous system malignancies.
IDrugs : the investigational drugs journal 20060601
-
Antilymphoid antibody preconditioning and tacrolimus monotherapy for pediatric kidney transplantation.
The Journal of pediatrics 20060601
-
Solitary pancreas transplantation for life-threatening allergy to human insulin.
Transplant international : official journal of the European Society for Organ Transplantation 20060601
-
Percutaneous stenting of the left main with drug eluting stents for in-stent restenosis: immediate- and long-term results.
The Journal of invasive cardiology 20060601
-
Sirolimus-induced pulmonary hypersensitivity associated with a CD4 T-cell infiltrate.
Chest 20060601
-
Drug-eluting stents for infrainguinal occlusive disease: progress and challenges.
Seminars in vascular surgery 20060601
-
Targeting mTOR for cancer treatment.
Current opinion in investigational drugs (London, England : 2000) 20060601
-
Conversion from calcineurin inhibitors to sirolimus in patients with chronic renal allograft dysfunction.
Transplantation proceedings 20060601
-
Sirolimus-induced intractable chronic diarrhea: a case report.
Transplantation proceedings 20060601
-
New therapies in the treatment of breast cancer.
Seminars in oncology 20060601
-
Molecular targeting therapy for renal cell carcinoma.
International journal of clinical oncology 20060601
-
A comparison of measured trough levels and abbreviated AUC estimation by limited sampling strategies for monitoring mycophenolic acid exposure in stable heart transplant patients receiving cyclosporin A-containing and cyclosporin A-free immunosuppressive regimens.
Clinical therapeutics 20060601
-
Switching immunosuppressive drugs in kidney transplant recipients: 'show me the evidence'.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20060601
-
No effect of sirolimus for kaposi sarcoma in a renal transplant recipient.
Transplantation 20060527
-
Autophagy: is it cancer's friend or foe?
Science (New York, N.Y.) 20060526
-
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells.
Nature 20060525
-
Functional genomics identifies TOR-regulated genes that control growth and division.
Current biology : CB 20060523
-
Conversion to sirolimus immunosuppression in liver transplantation recipients with hepatocellular carcinoma: Report of an initial experience.
World journal of gastroenterology 20060521
-
Predictive factors of restenosis after coronary implantation of sirolimus- or paclitaxel-eluting stents.
Circulation 20060516
-
Long-term outcomes after stenting of bifurcation lesions with the 'crush' technique: predictors of an adverse outcome.
Journal of the American College of Cardiology 20060516
-
Incomplete neointimal coverage of sirolimus-eluting stents: angioscopic findings.
Journal of the American College of Cardiology 20060516
-
Target of rapamycin inhibitors (sirolimus and everolimus) for primary immunosuppression of kidney transplant recipients: a systematic review and meta-analysis of randomized trials.
Transplantation 20060515
-
Stm1p, a ribosome-associated protein, is important for protein synthesis in Saccharomyces cerevisiae under nutritional stress conditions.
Journal of molecular biology 20060512
-
Neuroscience. Regulating energy balance: the substrate strikes back.
Science (New York, N.Y.) 20060512
-
Hypothalamic mTOR signaling regulates food intake.
Science (New York, N.Y.) 20060512
-
Predictive factors of cardiac events after implantation of sirolimus-eluting stents for treatment of in-stent restenosis.
International journal of cardiology 20060510
-
Involvement of protein synthesis and degradation in long-term potentiation of Schaffer collateral CA1 synapses.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20060503
-
Life-threatening coronary artery spasm following sirolimus-eluting stent deployment.
Journal of the American College of Cardiology 20060502
-
Endothelial dysfunction after drug-eluting stent was never predicted in preclinical studies.
Journal of the American College of Cardiology 20060502
-
Limitations of crush technique.
Journal of the American College of Cardiology 20060502
-
Drug eluting stents: an updated meta-analysis of randomised controlled trials.
Heart (British Cardiac Society) 20060501
-
Late coronary thrombosis in a sirolimus-eluting stent due to the lack of neointimal coverage.
European heart journal 20060501
-
Efficacy of drug eluting stents in patients with and without diabetes mellitus: indirect comparison of controlled trials.
Heart (British Cardiac Society) 20060501
-
In vivo antitumor effect of the mTOR inhibitor CCI-779 and gemcitabine in xenograft models of human pancreatic cancer.
International journal of cancer 20060501
-
Abnormal growth of smooth muscle-like cells in lymphangioleiomyomatosis: Role for tumor suppressor TSC2.
American journal of respiratory cell and molecular biology 20060501
-
Interferon-gamma-induced dephosphorylation of STAT3 and apoptosis are dependent on the mTOR pathway.
Experimental cell research 20060501
-
Role of drug eluting stents in diabetic patients.
Heart (British Cardiac Society) 20060501
-
Drug-eluting stents studies in mice: do we need atherosclerosis to study restenosis?
Vascular pharmacology 20060501
-
Inhibition of the mammalian target of rapamycin (mTOR) by rapamycin increases chemosensitivity of CaSki cells to paclitaxel.
European journal of cancer (Oxford, England : 1990) 20060501
-
Locally administered antiproliferative drugs inhibit hypercontractility to serotonin in balloon-injured pig coronary artery.
Vascular pharmacology 20060501
-
Differentiation of innovator versus generic cyclosporine via a drug interaction on sirolimus.
European journal of clinical pharmacology 20060501
-
Mammalian target of rapamycin pathway blockade slows progression of diabetic kidney disease in rats.
Journal of the American Society of Nephrology : JASN 20060501
-
Wound healing complications with de novo sirolimus versus mycophenolate mofetil-based regimen in cardiac transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060501
-
Sequential kidney/islet transplantation: efficacy and safety assessment of a steroid-free immunosuppression protocol.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060501
-
Colonic perforation associated with leukocytoclastic vasculitis caused by Sirolimus toxicity following renal transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20060501
-
Sirolimus-induced remission of posttransplantation lymphoproliferative disorder.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20060501
-
Comparison of safety and efficacy of sirolimus-eluting stents versus bare metal stents in patients with ST-segment elevation myocardial infarction.
The American journal of cardiology 20060501
-
C-Reactive protein, clinical outcome, and restenosis rates after implantation of different drug-eluting stents.
The American journal of cardiology 20060501
-
A prospective registry to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions using the 'crush technique'.
The American journal of cardiology 20060501
-
Voriconazole and sirolimus coadministration after allogeneic hematopoietic stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20060501
-
Sirolimus-eluting coronary stents in small vessels.
American heart journal 20060501
-
Survival signaling by Notch1: mammalian target of rapamycin (mTOR)-dependent inhibition of p53.
Cancer research 20060501
-
Everolimus (RAD) inhibits in vivo growth of murine squamous cell carcinoma (SCC VII).
The Laryngoscope 20060501
-
Comparison between sirolimus- and Paclitaxel-eluting stents for the treatment of chronic total occlusions.
The Journal of invasive cardiology 20060501
-
Sirolimus or paclitaxel drug-eluting stents for treatment of chronic total occlusions of coronary arteries: much ado about very little.
The Journal of invasive cardiology 20060501
-
Sirolimus rescue for tacrolimus-associated post-transplant autoimmune hemolytic anemia.
Pediatric transplantation 20060501
-
Early renal benefit of rapamycin combined with reduced calcineurin inhibitor dose in pediatric heart transplantation patients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060501
-
Integrated coronary revascularization with drug-eluting stents: immediate and seven-month outcome.
The Journal of thoracic and cardiovascular surgery 20060501
-
Autophagy: A protective mechanism in response to stress and inflammation.
Current opinion in investigational drugs (London, England : 2000) 20060501
-
Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer.
Molecular cancer therapeutics 20060501
-
Green tea extract and (-)-epigallocatechin-3-gallate inhibit hypoxia- and serum-induced HIF-1alpha protein accumulation and VEGF expression in human cervical carcinoma and hepatoma cells.
Molecular cancer therapeutics 20060501
-
Possible molecular target therapy with rapamycin in MDS.
Leukemia & lymphoma 20060501
-
Cutaneous leukocytoclastic vasculitis in a patient with myelodysplastic syndrome after therapy with the rapamycin analogue everolimus: case report and review of the literature.
Leukemia & lymphoma 20060501
-
Drug eluting stents: data from a clinical registry.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20060501
-
Long-term results of kidney transplantation with cyclosporine- and everolimus-based immunosuppression.
Transplantation proceedings 20060501
-
Incidence of posttransplant diabetes mellitus in kidney transplant recipients immunosuppressed with sirolimus in combination with cyclosporine.
Transplantation proceedings 20060501
-
Lymphocele after renal transplantation: the influence of the immunosuppressive therapy.
Transplantation proceedings 20060501
-
[Effects of rapamycin on Rho-kinase and p27 mRNA expressions in a porcine coronary intimal proliferation model induced by interleukin-1beta].
Zhonghua xin xue guan bing za zhi 20060501
-
mTOR, Akt, S6 kinases and the control of skeletal muscle growth.
Bulletin du cancer 20060501
-
[The PI3K/Akt/mTOR pathway: a new therapeutic target in the treatment of acute myeloid leukemia].
Bulletin du cancer 20060501
-
CCI-779 inhibits rhabdomyosarcoma xenograft growth by an antiangiogenic mechanism linked to the targeting of mTOR/Hif-1alpha/VEGF signaling.
Neoplasia (New York, N.Y.) 20060501
-
Sirolimus early graft nephrotoxicity: clinical and experimental data.
Current drug safety 20060501
-
Inhibition of corneal neovascularization by rapamycin.
Experimental & molecular medicine 20060430
-
Pancreas transplantation utilizing thymoglobulin, sirolimus, and cyclosporine.
Transplantation 20060427
-
GATA factor translation is the final downstream step in the amino acid/target-of-rapamycin-mediated vitellogenin gene expression in the anautogenous mosquito Aedes aegypti.
The Journal of biological chemistry 20060421
-
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB.
Molecular cell 20060421
-
mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin.
The EMBO journal 20060419
-
Target of rapamycin inhibitors (TOR-I; sirolimus and everolimus) for primary immunosuppression in kidney transplant recipients.
The Cochrane database of systematic reviews 20060419
-
Oral rapamycin after coronary bare-metal stent implantation to prevent restenosis: the Prospective, Randomized Oral Rapamycin in Argentina (ORAR II) Study.
Journal of the American College of Cardiology 20060418
-
Distal left main coronary disease is a major predictor of outcome in patients undergoing percutaneous intervention in the drug-eluting stent era: an integrated clinical and angiographic analysis based on the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) and Taxus-Stent Evaluated At Rotterdam Cardiology Hospital (T-SEARCH) registries.
Journal of the American College of Cardiology 20060418
-
Mechanical stimuli and nutrients regulate rapamycin-sensitive signaling through distinct mechanisms in skeletal muscle.
Journal of cellular biochemistry 20060415
-
SUMO modification through rapamycin-mediated heterodimerization reveals a dual role for Ubc9 in targeting RanGAP1 to nuclear pore complexes.
Experimental cell research 20060415
-
Improved renal function after conversion from tacrolimus/sirolimus to tacrolimus/mycophenolate mofetil in kidney transplant recipients.
Transplantation 20060415
-
Comparison of sirolimus versus paclitaxel eluting stents for treatment of coronary in-stent restenosis.
The American journal of cardiology 20060415
-
Usefulness and safety of percutaneous coronary interventions for cardiac transplant vasculopathy.
The American journal of cardiology 20060415
-
Rapamycin inhibits growth of premalignant and malignant mammary lesions in a mouse model of ductal carcinoma in situ.
Clinical cancer research : an official journal of the American Association for Cancer Research 20060415
-
[Drug-eluting stents: do they keep their promises?].
Praxis 20060412
-
Outcomes of using Firebird rapamycin eluting stents in routine coronary intervention practice: one-year results from the pilot study of Firebird in China registry.
Chinese medical journal 20060405
-
Two-year outcomes after sirolimus-eluting stent implantation: results from the Sirolimus-Eluting Stent in de Novo Native Coronary Lesions (SIRIUS) trial.
Journal of the American College of Cardiology 20060404
-
Sirolimus-eluting stents remain superior to bare-metal stents at two years: medium-term results from the Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry.
Journal of the American College of Cardiology 20060404
-
Drug-eluting stents are safe and effective: right or wrong?
Journal of the American College of Cardiology 20060404
-
Summaries for patients. Twenty-four cases of pneumonitis in kidney transplantation recipients receiving sirolimus.
Annals of internal medicine 20060404
-
Brief communication: sirolimus-associated pneumonitis: 24 cases in renal transplant recipients.
Annals of internal medicine 20060404
-
Identification and characterization of a constitutively T-loop phosphorylated and active recombinant S6K1: expression, purification, and enzymatic studies in a high capacity non-radioactive TR-FRET Lance assay.
Protein expression and purification 20060401
-
mTOR pathway inhibition attenuates skeletal muscle growth induced by stretching.
Cell and tissue research 20060401
-
Immunoglobulin G from patients with Graves' disease induces interleukin-16 and RANTES expression in cultured human thyrocytes: a putative mechanism for T-cell infiltration of the thyroid in autoimmune disease.
Endocrinology 20060401
-
Zotarolimus-eluting stents reduce experimental coronary artery neointimal hyperplasia after 4 weeks.
European heart journal 20060401
-
Rapamycin pre-treatment protects against apoptosis.
Human molecular genetics 20060401
-
Impact of overlapping drug-eluting stents in patients undergoing percutaneous coronary intervention.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060401
-
Prolonged survival of allogeneic islets in cynomolgus monkeys after short-term anti-CD154-based therapy: nonimmunologic graft failure?
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060401
-
Rapamycin attenuates liver graft injury in cirrhotic recipient--the significance of down-regulation of Rho-ROCK-VEGF pathway.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060401
-
Effects of rapamycin on number activity and eNOS of endothelial progenitor cells from peripheral blood.
Cell proliferation 20060401
-
Multi-center evaluation of analytical performance of the microparticle enzyme immunoassay for sirolimus.
Clinical biochemistry 20060401
-
Comparison of the effectiveness of sirolimus- and paclitaxel-eluting stents for small coronary artery lesions.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060401
-
Everolimus in pulmonary transplantation: pharmacokinetics and exposure-response relationships.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060401
-
Acute renal failure in a liver transplant patient after treatment with sirolimus.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20060401
-
Are drug-eluting stents cost-effective when compared with bare-metal stents in a real-world setting?
Nature clinical practice. Cardiovascular medicine 20060401
-
Percutaneous transluminal angioplasty for treatment of ''below-the-knee'' critical limb ischemia: early outcomes following the use of sirolimus-eluting stents.
The Journal of cardiovascular surgery 20060401
-
Simultaneous corticosteroid avoidance and calcineurin inhibitor minimization in renal transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20060401
-
Sirolimus and FK778: a comparison of two anti-proliferative immunosuppressants for prevention of experimental obliterative airway disease.
Transplant international : official journal of the European Society for Organ Transplantation 20060401
-
How to revascularize patients with diabetes mellitus: bypass or stents and drugs?
Clinical research in cardiology : official journal of the German Cardiac Society 20060401
-
Managing the introduction of expensive medical procedures: use of a registry.
Journal of health services research & policy 20060401
-
[Technical evolution of the stent].
Nihon rinsho. Japanese journal of clinical medicine 20060401
-
Comparison of the reintroduced MEIA assay with HPLC-MS/MS for the determination of whole-blood sirolimus from transplant recipients.
Therapeutic drug monitoring 20060401
-
Determination of mycophenolic acid plasma levels in renal transplant recipients co-administered sirolimus: comparison of an enzyme multiplied immunoassay technique (EMIT) and liquid chromatography-tandem mass spectrometry.
Therapeutic drug monitoring 20060401
-
Resolution of sirolimus-induced pneumonitis after conversion to everolimus.
Transplantation proceedings 20060401
-
Side effects of sirolimus.
Transplantation proceedings 20060401
-
Antiproliferative and overadditive effects of everolimus and mycophenolate mofetil in pancreas and lung cancer cells in vitro.
Transplantation proceedings 20060401
-
Recommendations for use of everolimus after heart transplantation: results from a Latin-American Consensus Meeting.
Transplantation proceedings 20060401
-
Efficacy of sirolimus-eluting stents as compared to paclitaxel-eluting stents for saphenous vein graft intervention.
Journal of interventional cardiology 20060401
-
Two-year follow-up of sirolimus-eluting stents for the treatment of proximal left anterior descending coronary artery stenosis.
Journal of interventional cardiology 20060401
-
Novel regulatory properties of Saccharomyces cerevisiae Arp4.
Journal of biochemistry 20060401
-
[Sirolimus-eluting stents for the treatment of stenoses in small coronary arteries: what have we learned?].
Arquivos brasileiros de cardiologia 20060401
-
[Comparative analysis of intimal hyperplasia after sirolimus-eluting stent and thin-strut bare-metal stent implantation in small coronary arteries].
Arquivos brasileiros de cardiologia 20060401
-
[Molecular targets in colon cancer].
Therapeutische Umschau. Revue therapeutique 20060401
-
Long-term follow up after coronary sirolimus drug-eluting stent implantation for cardiac transplant arteriopathy.
The Journal of invasive cardiology 20060401
-
Long-term follow up of diabetic patients treated with sirolimus-eluting stents. An angiographic and three-dimensional intravascular ultrasound study.
The Journal of invasive cardiology 20060401
-
Future directions in the treatment of hormone-sensitive advanced breast cancer: the RAD001 (Everolimus)-letrozole clinical program.
Seminars in oncology 20060401
-
[The femoral artery: the most complex peripheral vessel].
Herz 20060401
-
[The impact of expansion of sirolimus eluting stent on intimal hyperplasia: an intravascular ultrasound study].
Zhonghua xin xue guan bing za zhi 20060401
-
Future anti-catabolic therapeutic targets in bone disease.
Annals of the New York Academy of Sciences 20060401
-
A randomized long-term trial of tacrolimus/sirolimus versus tacrolimums/mycophenolate versus cyclosporine/sirolimus in renal transplantation: three-year analysis.
Transplantation 20060327
-
Stimulation of the creatine transporter SLC6A8 by the protein kinase mTOR.
Biochemical and biophysical research communications 20060324
-
Successful management of left main coronary artery stenosis with a paclitaxel-eluting stent in Takayasu's arteritis.
International journal of cardiology 20060322
-
Biosynthesis of pipecolic acid by RapL, a lysine cyclodeaminase encoded in the rapamycin gene cluster.
Journal of the American Chemical Society 20060322
-
Safety of coronary sirolimus-eluting stents in daily clinical practice: one-year follow-up of the e-Cypher registry.
Circulation 20060321
-
The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscle.
Proceedings of the National Academy of Sciences of the United States of America 20060321
-
Blockade of CD154-CD40 pathway induces interleukin-10 dependent T regulatory type 1 like cells.
Chinese medical journal 20060320
-
A nuclear transport signal in mammalian target of rapamycin is critical for its cytoplasmic signaling to S6 kinase 1.
The Journal of biological chemistry 20060317
-
Mammalian target of rapamycin (mTOR) regulates both proliferation of megakaryocyte progenitors and late stages of megakaryocyte differentiation.
Blood 20060315
-
Impact of chronic renal insufficiency on clinical outcomes in patients undergoing percutaneous coronary intervention with sirolimus-eluting stents versus bare metal stents.
The American journal of cardiology 20060315
-
Sirolimus-eluting stents vs vascular brachytherapy for in-stent restenosis within bare-metal stents: the SISR randomized trial.
JAMA 20060315
-
Brachytherapy for in-stent restenosis: a distant second choice to drug-eluting stent placement.
JAMA 20060315
-
Switch from calcineurin inhibitors to sirolimus-induced renal recovery in heart transplant recipients in the midterm follow-up.
Transplantation 20060315
-
An open prospective pilot study on the use of rapamycin after penetrating high-risk keratoplasty.
Transplantation 20060315
-
New drug application 21-628, Certican (everolimus), for the proposed indication of prophylaxis of rejection in heart transplantation: report from the Cardiovascular and Renal Drugs Advisory Committee, US Food and Drug Administration, November 16, 2005, Rockville, Md.
Circulation 20060314
-
Clinical islet transplantation in type 1 diabetes mellitus: results of Australia's first trial.
The Medical journal of Australia 20060306
-
Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD).
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060301
-
Rapamycin inhibits hTERT telomerase mRNA expression, independent of cell cycle arrest.
Gynecologic oncology 20060301
-
Molecular activity of sirolimus and its possible application in tuberous sclerosis treatment.
Medicinal research reviews 20060301
-
Conversion from calcineurin inhibitors to sirolimus in chronic allograft nephropathy: benefits and risks.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060301
-
[Sirolimus-associated interstitial pneumonitis in a renal transplant patient].
La Revue de medecine interne 20060301
-
Sirolimus in de novo heart transplant recipients with severe renal impairment.
Transplant international : official journal of the European Society for Organ Transplantation 20060301
-
Rapamycin causes regression of astrocytomas in tuberous sclerosis complex.
Annals of neurology 20060301
-
Complete avoidance of calcineurin inhibitors in renal transplantation: a randomized trial comparing sirolimus and tacrolimus.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060301
-
Tacrolimus combined with two different dosages of sirolimus in kidney transplantation: results of a multicenter study.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060301
-
Restenosis of a sirolimus drug-eluting stent: aorto-ostial involvement of the proximal right coronary artery.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060301
-
Novel apoptosis assay to analyze immunosuppression.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060301
-
Differing responses of Gat1 and Gln3 phosphorylation and localization to rapamycin and methionine sulfoximine treatment in Saccharomyces cerevisiae.
FEMS yeast research 20060301
-
Drug-eluting stent-supported percutaneous coronary intervention for chronic total coronary occlusion.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060301
-
Is late luminal loss an accurate predictor of the clinical effectiveness of drug-eluting stents in the coronary arteries?
The American journal of cardiology 20060301
-
Impact of three or more versus a single sirolimus-eluting stent on outcomes in patients who undergo percutaneous coronary intervention.
The American journal of cardiology 20060301
-
Percutaneous coronary interventions with stents in cardiac transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060301
-
Mechanistic insights into achievement of cardiac allograft long-term survival by treatment with immature dendritic cells and sub-dose sirolimus.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060301
-
Calcium signaling stimulates translation of HIF-alpha during hypoxia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301
-
Perspectives in gynecologic oncology -- Third European Conference.
IDrugs : the investigational drugs journal 20060301
-
Using 'bumps' and 'holes' to control protein activity.
Nature methods 20060301
-
IRS-1: auditing the effectiveness of mTOR inhibitors.
Cancer cell 20060301
-
Individualization of immunosuppressive therapy. III. Sirolimus associated with a reduced incidence of malignancy.
Transplantation proceedings 20060301
-
Cutaneous effects of sirolimus in renal transplant recipients.
Journal of drugs in dermatology : JDD 20060301
-
[Stroma-targeted palliative tumor therapy with biomodulators].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20060301
-
Economic evaluation of drug-eluting stents in Japan.
The Keio journal of medicine 20060301
-
[Two-year clinical follow-up in 200 patients receiving sirolimus-eluting stents in lesions at a high risk of restenosis].
Revista espanola de cardiologia 20060301
-
Correlates and long-term outcomes of angiographically proven stent thrombosis with sirolimus- and paclitaxel-eluting stents.
Circulation 20060227
-
Human allograft arterial injury is ameliorated by sirolimus and cyclosporine and correlates with suppression of interferon-gamma.
Transplantation 20060227
-
Tacrolimus-associated optic neuropathy after pancreatic islet transplantation using a sirolimus/tacrolimus immunosuppressive regimen.
Transplantation 20060227
-
Pregnancy under sirolimus-based immunosuppression.
Transplantation 20060227
-
Sirolimus- vs paclitaxel-eluting stents in de novo coronary artery lesions: the REALITY trial: a randomized controlled trial.
JAMA 20060222
-
Wish list and REALITY: choice of stents and end points for treatment of de novo coronary artery lesions.
JAMA 20060222
-
Sirolimus and Paclitaxel on polymer-based drug-eluting stents: similar but different.
Journal of the American College of Cardiology 20060221
-
Serial angiographic follow-up of sirolimus-eluting stents for unprotected left main coronary artery revascularization.
Journal of the American College of Cardiology 20060221
-
Drug-eluting stenting for unprotected left main coronary artery disease: are we ready to replace bypass surgery?
Journal of the American College of Cardiology 20060221
-
Late stent malapposition and marked positive vessel remodeling after sirolimus-eluting coronary stent implantation.
Chinese medical journal 20060220
-
Effects of drug combinations on smooth muscle cell proliferation: an isobolographic analysis.
European journal of pharmacology 20060217
-
In yeast, loss of Hog1 leads to osmosensitivity of autophagy.
The Biochemical journal 20060215
-
A comparison of sirolimus vs. calcineurin inhibitor-based immunosuppressive therapies in liver transplantation.
Alimentary pharmacology & therapeutics 20060215
-
Inhibition of TPO-induced MEK or mTOR activity induces opposite effects on the ploidy of human differentiating megakaryocytes.
Journal of cell science 20060215
-
Comparison between sirolimus- and paclitaxel-eluting stent in T-cell subsets redistribution.
The American journal of cardiology 20060215
-
Angiographic pattern of restenosis following implantation of overlapping sirolimus-eluting (Cypher) stents.
The American journal of cardiology 20060215
-
Predictors of restenosis after placement of drug-eluting stents in one or more coronary arteries.
The American journal of cardiology 20060215
-
Posttransplant diabetes mellitus in kidney transplant recipients receiving calcineurin or mTOR inhibitor drugs.
Transplantation 20060215
-
Conversion to sirolimus and mycophenolate can attenuate the progression of bronchiolitis obliterans syndrome and improves renal function after lung transplantation.
Transplantation 20060215
-
Rapamycin does not induce anergy but inhibits expansion and differentiation of alloreactive human T cells.
Transplantation 20060215
-
Mechanism by which mammalian target of rapamycin inhibitors sensitize multiple myeloma cells to dexamethasone-induced apoptosis.
Cancer research 20060215
-
Glucose-stimulated DNA synthesis through mammalian target of rapamycin (mTOR) is regulated by KATP channels: effects on cell cycle progression in rodent islets.
The Journal of biological chemistry 20060210
-
Sirolimus-eluting versus paclitaxel-eluting stent implantation for the percutaneous treatment of left main coronary artery disease: a combined RESEARCH and T-SEARCH long-term analysis.
Journal of the American College of Cardiology 20060207
-
Regression of cutaneous and gastrointestinal telangiectasia with sirolimus and aspirin in a patient with hereditary hemorrhagic telangiectasia.
Annals of internal medicine 20060207
-
Inhibition of mTOR signaling with rapamycin attenuates renal hypertrophy in the early diabetic mice.
Biochemical and biophysical research communications 20060203
-
Coronary-artery stents.
The New England journal of medicine 20060202
-
Simultaneous determination of everolimus and cyclosporine concentrations by HPLC with ultraviolet detection.
Clinica chimica acta; international journal of clinical chemistry 20060201
-
The mTOR inhibitor CCI-779 induces apoptosis and inhibits growth in preclinical models of primary adult human ALL.
Blood 20060201
-
Rapamycin, and not cyclosporin A, preserves the highly suppressive CD27+ subset of human CD4+CD25+ regulatory T cells.
Blood 20060201
-
Adaptor heat shock protein complex formation regulates trafficking of the asialoglycoprotein receptor.
American journal of physiology. Gastrointestinal and liver physiology 20060201
-
Conversion from calcineurin inhibitors to sirolimus in chronic allograft dysfunction: changes in glomerular haemodynamics and proteinuria.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060201
-
The Saccharomyces cerevisiae phosphatase activator RRD1 is required to modulate gene expression in response to rapamycin exposure.
Genetics 20060201
-
Involvement of multiple phosphatidylinositol 3-kinase-dependent pathways in the persistence of late-phase long term potentiation expression.
Neuroscience 20060201
-
mTOR and cancer: reason for dancing at the crossroads?
Current opinion in genetics & development 20060201
-
Rapamycin alleviates toxicity of different aggregate-prone proteins.
Human molecular genetics 20060201
-
Individualizing combination of two antiproliferative immunosuppressants with pharmacodynamic modeling of stimulated lymphocyte responses.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060201
-
Prevention of carotid artery restenosis after sirolimus-coated stent implantation in pigs.
Stroke 20060201
-
Comparison of sirolimus-eluting stent, paclitaxel-eluting stent, and bare metal stent in the treatment of long coronary lesions.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060201
-
Revisiting late loss and neointimal volumetric measurements in a drug-eluting stent trial: analysis from the SPIRIT FIRST trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060201
-
Mycotic aneurysms after sirolimus-eluting coronary stenting.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060201
-
Randomized trial of paclitaxel- and sirolimus-eluting stents in small coronary vessels.
European heart journal 20060201
-
Microarray-based method for monitoring yeast overexpression strains reveals small-molecule targets in TOR pathway.
Nature chemical biology 20060201
-
Pharmacokinetics and metabolic disposition of sirolimus in healthy male volunteers after a single oral dose.
Therapeutic drug monitoring 20060201
-
Sirolimus-associated heavy proteinuria in a renal transplant recipient: evidence for a tubular mechanism.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060201
-
Update on drug-eluting stents for prevention of restenosis.
Asian cardiovascular & thoracic annals 20060201
-
Sirolimus- or paclitaxel-eluting stents for coronary artery revascularisation.
Expert opinion on pharmacotherapy 20060201
-
Sirolimus therapy after early cyclosporine withdrawal reduces the risk for cancer in adult renal transplantation.
Journal of the American Society of Nephrology : JASN 20060201
-
Role of Erk1/2, p70s6K, and eNOS in isoflurane-induced cardioprotection during early reperfusion in vivo.
Canadian journal of anaesthesia = Journal canadien d'anesthesie 20060201
-
Renal calcium handling after rapamycin conversion in chronic allograft dysfunction.
Transplant international : official journal of the European Society for Organ Transplantation 20060201
-
Reversible sirolimus-associated pneumonitis after heart transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060201
-
Procedural success and 30 day outcomes between CYPHER and TAXUS stent implantation for the treatment of bifurcation lesions--a single-center experience.
The Journal of invasive cardiology 20060201
-
mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt.
Cancer research 20060201
-
Sirolimus-itraconazole interaction in a hematopoietic stem cell transplant recipient.
Pharmacotherapy 20060201
-
Phase 1 trial of gefitinib plus sirolimus in adults with recurrent malignant glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20060201
-
Percutaneous vascular interventions in the superficial femoral artery. A review.
Minerva cardioangiologica 20060201
-
TORgeting oncogene addiction for cancer therapy.
Cancer cell 20060201
-
Sirolimus-versus paclitaxel-eluting stents: a comparison of two consecutive series in routine clinical practice.
Journal of interventional cardiology 20060201
-
Editorial comment: which is the preferred drug-eluting stent?
Journal of interventional cardiology 20060201
-
Contemporary treatment of coronary bifurcations with drug-eluting stent: part II.
Journal of interventional cardiology 20060201
-
TCT 2005 late-breaking trials promise to influence practice patterns.
Journal of interventional cardiology 20060201
-
[Progress in therapeutic strategy for renal cell carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy 20060201
-
Dutasteride, cantharidin, atopiclair, cetuximab, sirolimus, AC-11 and dimericine reviewed in brief.
Journal of drugs in dermatology : JDD 20060201
-
Cryptogenic organizing pneumonia associated with Pneumocystis carinii infection and sirolimus therapy in a renal transplant patient.
Australasian radiology 20060201
-
Safety and long-term efficacy of sirolimus eluting stent in ST-elevation acute myocardial infarction: the REAL (Registro REgionale AngiopLastiche Emilia-Romagna) registry.
Cardiovascular drugs and therapy 20060201
-
[Insulin-dependent. Rapamycin-resistant?].
Revista espanola de cardiologia 20060201
-
[Efficacy of sirolimus-eluting stents in diabetics with complex coronary lesions].
Revista espanola de cardiologia 20060201
-
[Comparison of Rapamycin and Paclitaxel eluting stent in patients with multi-vessel coronary disease].
Zhonghua xin xue guan bing za zhi 20060201
-
[Coronary artery atherosclerotic plaque and stent visualizations by optical coherence tomography].
Zhonghua xin xue guan bing za zhi 20060201
-
[Effect of inhibitors of signal transducer and activator of transcription-1/3 on expression of tumor necrosis factor-alpha induced by high mobility group box-1 protein inflammatory response in rat peritoneal macrophages].
Zhonghua wai ke za zhi [Chinese journal of surgery] 20060201
-
Targeting mTOR signaling for lung cancer therapy.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20060201
-
mTOR signaling: implications for cancer and anticancer therapy.
British journal of cancer 20060130
-
Delayed strut fracture of sirolimus-eluting stent: a significant problem or an occasional observation?
International journal of cardiology 20060126
-
Late stent malapposition after drug-eluting stent implantation: an intravascular ultrasound analysis with long-term follow-up.
Circulation 20060124
-
One-year clinical outcomes of Chinese sirolimus-eluting stent in the treatment of unselected patients with coronary artery disease.
Chinese medical journal 20060120
-
Randomized trial of a nonpolymer-based rapamycin-eluting stent versus a polymer-based paclitaxel-eluting stent for the reduction of late lumen loss.
Circulation 20060117
-
The Stenting Coronary Arteries in Non-stress/benestent Disease (SCANDSTENT) trial.
Journal of the American College of Cardiology 20060117
-
Hamartin, the tuberous sclerosis complex 1 gene product, interacts with polo-like kinase 1 in a phosphorylation-dependent manner.
Human molecular genetics 20060115
-
Thrombotic microangiopathy after lung transplantation.
Transplantation 20060115
-
Rapamycin prolongs susceptibility of responding T cells to tolerance induction by CD8+ veto cells.
Transplantation 20060115
-
Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice.
Cancer research 20060115
-
Rapamycin disrupts cyclin/cyclin-dependent kinase/p21/proliferating cell nuclear antigen complexes and cyclin D1 reverses rapamycin action by stabilizing these complexes.
Cancer research 20060115
-
Early outcome of treatment of ostial de novo left anterior descending coronary artery lesions with drug-eluting stents.
The American journal of cardiology 20060115
-
Intravascular ultrasound characterization of the 'black hole' phenomenon after drug-eluting stent implantation.
The American journal of cardiology 20060115
-
Novel roles of Akt and mTOR in suppressing TGF-beta/ALK5-mediated Smad3 activation.
The EMBO journal 20060111
-
In vitro release of the mTOR inhibitor rapamycin from poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles.
Journal of controlled release : official journal of the Controlled Release Society 20060110
-
Phosphoinositide 3-kinase: from viral oncoprotein to drug target.
Virology 20060105
-
Comparison of short- and mid-term outcomes between CYPHER and TAXUS stents in patients with complex lesions of the coronary arteries.
Chinese medical journal 20060105
-
Thrombosis after implantation of drug-eluting stents.
JAMA 20060104
-
Are drug-eluting stents the preferred treatment for multivessel coronary artery disease?
Journal of the American College of Cardiology 20060103
-
Hypersensitivity cases associated with drug-eluting coronary stents: a review of available cases from the Research on Adverse Drug Events and Reports (RADAR) project.
Journal of the American College of Cardiology 20060103
-
Allergic reactions after the implantation of drug-eluting stents: is it the pill or the polymer?
Journal of the American College of Cardiology 20060103
-
Coronary stent thrombosis in the current drug-eluting stent era: insights from the ERACI III trial.
Journal of the American College of Cardiology 20060103
-
Drug-eluting stent thrombosis: a pooled analysis.
Journal of the American College of Cardiology 20060103
-
Cost effectiveness of drug eluting coronary artery stenting in a UK setting: cost-utility study.
Heart (British Cardiac Society) 20060101
-
N-acetyl-cysteine abolishes hydrogen peroxide-induced modification of eukaryotic initiation factor 4F activity via distinct signalling pathways.
Cellular signalling 20060101
-
Enhanced cytotoxicity induced by gefitinib and specific inhibitors of the Ras or phosphatidyl inositol-3 kinase pathways in non-small cell lung cancer cells.
International journal of cancer 20060101
-
Early elevation of interleukin-1beta and interleukin-6 levels after bare or drug-eluting stent implantation in patients with stable angina.
Thrombosis research 20060101
-
Mammalian target of rapamycin is required for thrombopoietin-induced proliferation of megakaryocyte progenitors.
Stem cells (Dayton, Ohio) 20060101
-
Dimerizer regulation of AADC expression and behavioral response in AAV-transduced 6-OHDA lesioned rats.
Molecular therapy : the journal of the American Society of Gene Therapy 20060101
-
Patterns of pulmonary complications associated with sirolimus.
Respiration; international review of thoracic diseases 20060101
-
Rapamycin control of transgene expression from a single AAV vector in mouse salivary glands.
Gene therapy 20060101
-
Social inhibition modulates the effect of negative emotions on cardiac prognosis following percutaneous coronary intervention in the drug-eluting stent era.
European heart journal 20060101
-
Indication of long-term endothelial dysfunction after sirolimus-eluting stent implantation.
European heart journal 20060101
-
Coronary endothelial dysfunction following sirolimus-eluting stent placement: should we worry about it?
European heart journal 20060101
-
Sirolimus PK trial: a pharmacokinetic study of the sirolimus-eluting Bx velocity stent in patients with de novo coronary lesions.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060101
-
Heme oxygenase-1 mediates the protective effects of rapamycin in monocrotaline-induced pulmonary hypertension.
Laboratory investigation; a journal of technical methods and pathology 20060101
-
Marked erythrocyte microcytosis under primary immunosuppression with sirolimus.
Transplant international : official journal of the European Society for Organ Transplantation 20060101
-
Cardiac transplantation without calcineurin inhibitors. Sirolimus as first immunosuppressive line. Based on one case.
Transplant international : official journal of the European Society for Organ Transplantation 20060101
-
Images in cardiology. Acute recoil in sirolimus eluting stent: real time, in vivo assessment with optical coherence tomography.
Heart (British Cardiac Society) 20060101
-
From Rapa Nui to rapamycin: targeting PI3K/Akt/mTOR for cancer therapy.
Expert review of anticancer therapy 20060101
-
Efficacy of sirolimus-eluting stents compared with bare metal stents for saphenous vein graft intervention.
The American journal of cardiology 20060101
-
Natural killer T-cells participate in rejection of islet allografts in the liver of mice.
Diabetes 20060101
-
Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance.
Diabetes 20060101
-
Atrophic remodeling of the transplanted rat heart.
Cardiology 20060101
-
Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways.
Cancer research 20060101
-
A comparative study of sirolimus tablet versus oral solution for prophylaxis of acute renal allograft rejection.
Journal of clinical pharmacology 20060101
-
Relationship of cyclosporin and sirolimus blood concentrations regarding the incidence and severity of hyperlipidemia after kidney transplantation.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20060101
-
One year follow-up of sirolimus-eluting stent in a cardiac post-transplant patient.
The Journal of invasive cardiology 20060101
-
Kidney cancer: identification of novel targets for therapy.
Kidney international 20060101
-
Synergistic suppression of rat neointimal hyperplasia by rapamycin and imatinib mesylate: implications for the prevention of accelerated arteriosclerosis.
Journal of vascular research 20060101
-
Structure-activity relationship for noncoplanar polychlorinated biphenyl congeners toward the ryanodine receptor-Ca2+ channel complex type 1 (RyR1).
Chemical research in toxicology 20060101
-
Hypoxia-inducible factor-1alpha polymorphisms and TSC1/2 mutations are complementary in head and neck cancers.
Molecular cancer 20060101
-
Tolerance induction by third-party 'off-the-shelf' CD4+CD25+ Treg cells.
Experimental hematology 20060101
-
Accounting for strain-specific differences during RTG target gene regulation in Saccharomyces cerevisiae.
FEMS yeast research 20060101
-
Rapamycin analogs with differential binding specificity permit orthogonal control of protein activity.
Chemistry & biology 20060101
-
Apoptosis of allospecifically activated human helper T cells is blocked by calcineurin inhibition.
Transplant immunology 20060101
-
Everolimus versus azathioprine in maintenance lung transplant recipients: an international, randomized, double-blind clinical trial.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060101
-
Evaluation of the cost effectiveness of sirolimus versus tacrolimus for immunosuppression following renal transplantation in the UK.
PharmacoEconomics 20060101
-
NMR assignment of the mTOR domain responsible for rapamycin binding.
Journal of biomolecular NMR 20060101
-
Pulsed immunosuppression with everolimus and anti-alphabeta T-cell receptor: laryngeal allograft preservation at six months.
The Annals of otology, rhinology, and laryngology 20060101
-
[In-hospital and remote results of the use of sirolimus coated coronary stent CYPHER].
Kardiologiia 20060101
-
Successful reversal of acute vascular rejection and cyclosporine-associated nephrotoxicity in renal allograft with combined sirolimus and mycophenolate mofetil as immunotherapy.
Transplantation proceedings 20060101
-
Individualization of immunosuppressive therapy. II. Sirolimus as a less nephrotoxic alternative to calcineurin inhibitors.
Transplantation proceedings 20060101
-
Economic evaluation of sirolimus-based immunosuppressive regimens in kidney graft recipients.
Transplantation proceedings 20060101
-
High-performance liquid chromatography versus immunoassay for the measurement of sirolimus: comparison of two methods.
Transplantation proceedings 20060101
-
Conversion to sirolimus from cyclosporine may induce nephrotic proteinuria and progressive deterioration of renal function in chronic allograft nephropathy patients.
Transplantation proceedings 20060101
-
Hypoxia-inducible factor 1alpha (HIF-1alpha) correlated with tumor growth and apoptosis in ovarian cancer.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101
-
Thrombosis after implantation of drug-eluting stents.
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20060101
-
Efficacy of polyphenon E, red ginseng, and rapamycin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice.
Neoplasia (New York, N.Y.) 20060101
-
Early steroid withdrawal after renal transplantation.
Nephrology nursing journal : journal of the American Nephrology Nurses' Association 20060101
-
[Rapamycine and mTOR inhibitors: from bench to bedside].
Annales de biologie clinique 20060101
-
mTOR inhibitors.
Clinical advances in hematology & oncology : H&O 20060101
-
Mutual information-based feature selection in studying perturbation of dendritic structure caused by TSC2 inactivation.
Neuroinformatics 20060101
-
Everolimus: a review of its use in renal and cardiac transplantation.
Drugs 20060101
-
The engineering of endovascular stent technology: a review.
Vascular and endovascular surgery 20060101
-
[Stent therapy with diabetic patients who have coronary artery disease].
Clinical research in cardiology : official journal of the German Cardiac Society 20060101
-
Evaluation of an immunoassay of whole blood sirolimus in pediatric transplant patients in comparison with high-performance liquid chromatography/tandem mass spectrometry.
Clinical chemistry and laboratory medicine 20060101
-
The paclitaxel-eluting stent in percutaneous coronary intervention: Part II. Comparison with the sirolimus-eluting stent, economics, and unanswered questions.
Cardiology in review 20060101
-
[Sustained rapamycin drug delivery system in prevention of high risk corneal allograft rejection and neovascularization in rabbits].
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20060101
-
The drug-eluting stent dilemma: comparing the effectiveness of Cypher versus Taxus.
Journal of cardiovascular medicine (Hagerstown, Md.) 20060101
-
Sirolimus: friend or foe?
Respiration; international review of thoracic diseases 20060101
-
Rheb activation of mTOR and S6K1 signaling.
Methods in enzymology 20060101
-
The paradox of sirolimus-induced immunosuppression and tumor control.
Dermatology (Basel, Switzerland) 20060101
-
Posttransplant Kaposi's sarcoma restricted to the site of a previous deep venous thrombosis: abrupt onset after withdrawal of sirolimus.
Dermatology (Basel, Switzerland) 20060101
-
Cost effectiveness of the sirolimus-eluting stent in high-risk patients in Canada: an analysis from the C-SIRIUS trial.
American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101
-
Renal function in renal or liver transplant recipients after conversion from a calcineurin inhibitor to sirolimus.
Clinical transplantation 20060101
-
Role of FK778 alone or in combination with tacrolimus or mTOR inhibitors as an immunomodulator of immunofunctions: in vitro evaluation of T cell proliferation and the expression of lymphocyte surface antigens.
International journal of immunopathology and pharmacology 20060101
-
Cluster analysis of protein array results via similarity of Gene Ontology annotation.
BMC bioinformatics 20060101
-
Cost-effectiveness of sirolimus therapy with early cyclosporin withdrawal vs. long-term cyclosporin therapy in Australia.
Clinical transplantation 20060101
-
The mTOR inhibitor rapamycin down-regulates the expression of the ubiquitin ligase subunit Skp2 in breast cancer cells.
Breast cancer research : BCR 20060101
-
Role of cytomegalovirus and Epstein-Barr virus in patients with de novo colon cancer after renal transplantation.
Tumori 20060101
-
Protective roles for induction of autophagy in multiple proteinopathies.
Autophagy 20060101
-
Lysosomal turnover of GABARAP-phospholipid conjugate is activated during differentiation of C2C12 cells to myotubes without inactivation of the mTor kinase-signaling pathway.
Autophagy 20060101
-
Deletion of HOG1 leads to Osmosensitivity in starvation-induced, but not rapamycin-dependent Atg8 degradation and proteolysis: further evidence for different regulatory mechanisms in yeast autophagy.
Autophagy 20060101
-
Late acute thrombosis after implantation of sirolimus-eluting stent to treat in-stent restenosis.
Acute cardiac care 20060101
-
[Sirolimus-induced onychopathy in renal transplant recipients].
Annales de dermatologie et de venereologie 20060101
-
[Study of drugs against neoplastic metastasis].
Magyar onkologia 20060101
-
The mTOR pathway in breast cancer.
Journal of mammary gland biology and neoplasia 20060101
-
Conversion to sirolimus in pediatric renal transplantation recipients.
Transplantation proceedings 20060101
-
Validation of using gene expression in mononuclear cells as a marker for hepatic cholesterol metabolism.
Lipids in health and disease 20060101
-
Effect of cyclosporine and sirolimus on the expression of connective tissue growth factor in rat experimental chronic nephrotoxicity.
American journal of nephrology 20060101
-
Glycogen synthase kinase 3 has a limited role in cell cycle regulation of cyclin D1 levels.
BMC cell biology 20060101
-
Is sirolimus better than paclitaxel? A review of the comparative data on drug-eluting stents.
Cardiovascular revascularization medicine : including molecular interventions 20060101
-
Optimal dosing and duration of oral everolimus to inhibit in-stent neointimal growth in rabbit iliac arteries.
Cardiovascular revascularization medicine : including molecular interventions 20060101
-
Morphoproteomic and pharmacoproteomic rationale for mTOR effectors as therapeutic targets in head and neck squamous cell carcinoma.
Annals of clinical and laboratory science 20060101
-
Morphoproteomic and molecular concomitants of an overexpressed and activated mTOR pathway in renal cell carcinomas.
Annals of clinical and laboratory science 20060101
-
Evaluation of a microparticle enzyme immunoassay for the measurement of sirolimus in whole blood (Abbott IMx sirolimus).
Clinical laboratory 20060101
-
Oral immunosuppressive drugs.
Clinical medicine (London, England) 20060101
-
Excellent clinical outcomes in primary kidney transplant recipients treated with steroid-free maintenance immunosuppression.
Clinical transplantation 20060101
-
[Comparison of high-resolution liquid chromatography versus microparticle enzyme immunoassay for the measurement of sirolimus levels in renal transplantation].
Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20060101
-
Cardiac overexpression of metallothionein rescues chronic alcohol intake-induced cardiomyocyte dysfunction: role of Akt, mammalian target of rapamycin and ribosomal p70s6 kinase.
Alcohol and alcoholism (Oxford, Oxfordshire) 20060101
-
Sirolimus population pharmacokinetic/pharmacogenetic analysis and bayesian modelling in kidney transplant recipients.
Clinical pharmacokinetics 20060101
-
Method development and validation for zotarolimus concentration determination in stented swine arteries by liquid chromatography/tandem mass spectrometry detection.
Rapid communications in mass spectrometry : RCM 20060101
-
Successive, rapid recurrences of in-stent restenoses in a woman with angina pectoris.
Internal medicine (Tokyo, Japan) 20060101
-
Drug-eluting stents.
Archivos de cardiologia de Mexico 20060101
-
The role and value of sirolimus administration in kidney and liver transplantation.
Clinical transplantation 20060101
-
Sirolimus-induced interstitial pneumonitis.
Journal of postgraduate medicine 20060101
-
Switching from HPLC/UV to MEIA for whole blood sirolimus quantitation: comparison of methods.
Journal of clinical laboratory analysis 20060101
-
Regulating cell surface glycosylation with a small-molecule switch.
Methods in enzymology 20060101
-
Subacute thrombosis following implantation of zotarolimus-eluting stent.
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20060101
-
Sirolimus-associated proteinuria and renal dysfunction.
Drug safety 20060101
-
[Efficacy of the use of sirolimus covered stents in the treatment of diffuse atherosclerotic lesions of coronary arteries].
Kardiologiia 20060101
-
Targeting mTOR for cancer treatment.
Advances in experimental medicine and biology 20060101
-
Promoting vascular regeneration as an alternative to conventional angioplasty-based intervention.
Endothelium : journal of endothelial cell research 20060101
-
Comparison of paclitaxel-eluting stent and sirolimus-eluting stent expansion at incremental delivery pressures.
Cardiovascular revascularization medicine : including molecular interventions 20060101
-
Resolution of neurotoxicity and beta-cell toxicity in an islet transplant recipient following substitution of tacrolimus with MMF.
Cell transplantation 20060101
-
Thrombosis of drug-eluting stents: fact or fiction?
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20060101
-
Clinical benefits of drug-eluting stents: results from RAVEL and beyond.
The Journal of cardiovascular nursing 20060101
-
[Lung toxicity induced by rapamycin].
Revista portuguesa de pneumologia 20060101
-
Mammalian target of rapamycin is a promising target for novel therapeutic strategy against cancer.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20060101
-
[Use of 'Cypher' sirolimus-eluting stents in coronary heart disease patients with different types of coronary arterial lesions].
Vestnik rentgenologii i radiologii 20060101
-
Contribution of transplantation to the development of medical science. How transplantation contributes to the world of medicine.
Annals of transplantation 20060101
-
Sirolimus-eluting stents. (The results of the five-year use for the treatment of coronary artery disease).
Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20060101
-
A prospective, open-label trial of sirolimus in the treatment of focal segmental glomerulosclerosis.
Clinical journal of the American Society of Nephrology : CJASN 20060101
-
Preface. Sirolimus and kidney transplantation.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101
-
Current trends in immunosuppression.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101
-
Transplantation and tumors.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101
-
Sirolimus, the first mTOR inhibitor.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101
-
Sirolimus use in de 'novo renal' transplantation.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101
-
Conversion to sirolimus.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101
-
Handling sirolimus in clinical practice. Spanish Nephrology Society.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101
-
[Long-term clinical efficiency of endovascular treatment using Cypher rapamycin-eluting stents in patients with coronary heart disease].
Vestnik rentgenologii i radiologii 20060101
-
Anesthetic rejection followed by surgical salvage.
Clinical transplants 20060101
-
Cyclosporine A, FK-506, 40-0-[2-hydroxyethyl]rapamycin and mycophenolate mofetil inhibit proliferation of human intrahepatic biliary epithelial cells in vitro.
World journal of gastroenterology 20051228
-
Apolipoprotein E genotypes as predictors of high-risk groups for developing hyperlipidemia in kidney transplant recipients undergoing sirolimus treatment.
Transplantation 20051227
-
Sirolimus use and de novo minimal change nephropathy following renal transplantation.
Transplantation 20051227
-
mTOR regulates cell survival after etoposide treatment in primary AML cells.
Blood 20051215
-
Attenuation of cardiac hypertrophy by inhibiting both mTOR and NFkappaB activation in vivo.
Free radical biology & medicine 20051215
-
Comparison between sirolimus-eluting stents and intracoronary catheter-based beta radiation for the treatment of in-stent restenosis.
The American journal of cardiology 20051215
-
Clinical outcome following aleatory implantation of paclitaxel-eluting or sirolimus-eluting stents in complex coronary lesions.
The American journal of cardiology 20051215
-
Low-dose radiation plus rapamycin promotes long-term bone marrow chimerism.
Transplantation 20051215
-
Conversion from cyclosporine to sirolimus in stable renal transplant recipients.
Transplantation 20051215
-
Control of dendritic arborization by the phosphoinositide-3'-kinase-Akt-mammalian target of rapamycin pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20051207
-
Local and systemic drug competition in drug-eluting stent tissue deposition properties.
Journal of controlled release : official journal of the Controlled Release Society 20051205
-
Superiority of sirolimus eluting stent compared with intracoronary beta radiation for treatment of in-stent restenosis: a matched comparison.
Heart (British Cardiac Society) 20051201
-
Negative regulation of melanogenesis by phospholipase D1 through mTOR/p70 S6 kinase 1 signaling in mouse B16 melanoma cells.
Journal of cellular physiology 20051201
-
mTOR function in skeletal muscle hypertrophy: increased ribosomal RNA via cell cycle regulators.
American journal of physiology. Cell physiology 20051201
-
Enhancement of translation elongation in neurons by brain-derived neurotrophic factor: implications for mammalian target of rapamycin signaling.
Journal of neurochemistry 20051201
-
Rapamycin analogs with reduced systemic exposure.
Bioorganic & medicinal chemistry letters 20051201
-
Synergistic effect of targeting mTOR by rapamycin and depleting ATP by inhibition of glycolysis in lymphoma and leukemia cells.
Leukemia 20051201
-
Noninvasive imaging of protein-protein interactions from live cells and living subjects using bioluminescence resonance energy transfer.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051201
-
S6 kinase 2 potentiates interleukin-3-driven cell proliferation.
Journal of leukocyte biology 20051201
-
Rapamycin for treatment of chronic allograft nephropathy in renal transplant patients.
Journal of the American Society of Nephrology : JASN 20051201
-
Vascular response to sirolimus-eluting stents delivered with a nonaggressive implantation technique: comparison of intravascular ultrasound results from the multicenter, randomized E-SIRIUS, and SIRIUS trials.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20051201
-
In smooth muscle, FK506-binding protein modulates IP3 receptor-evoked Ca2+ release by mTOR and calcineurin.
Journal of cell science 20051201
-
Drug-eluting stents for the treatment of intracranial atherosclerosis: initial experience and midterm angiographic follow-up.
Stroke 20051201
-
Pilot study with an intensified oral sirolimus regimen for the prevention of in-stent restenosis in de novo lesions: a serial intravascular ultrasound study.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20051201
-
Pharmacokinetics of sirolimus (rapamycin) in subjects with mild to moderate hepatic impairment.
Journal of clinical pharmacology 20051201
-
Inhibition of target of rapamycin signaling by rapamycin in the unicellular green alga Chlamydomonas reinhardtii.
Plant physiology 20051201
-
Mechanisms of everolimus-induced glomerulosclerosis after glomerular injury in the rat.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051201
-
Influence of co-medication with sirolimus or cyclosporine on mycophenolic acid pharmacokinetics in kidney transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051201
-
Alemtuzumab induction and sirolimus plus mycophenolate mofetil maintenance for CNI and steroid-free kidney transplant immunosuppression.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051201
-
Calcineurin inhibitor withdrawal from sirolimus-based therapy in kidney transplantation: a systematic review of randomized trials.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051201
-
Development and validation of a high-throughput assay for quantification of the proliferation inhibitor ABT-578 using LC/LC-MS/MS in blood and tissue samples.
Therapeutic drug monitoring 20051201
-
Technology Insight: an overview of research in drug-eluting stents.
Nature clinical practice. Cardiovascular medicine 20051201
-
Thrombotic microangiopathy in marginal kidneys after sirolimus use.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20051201
-
Biochemical monitoring of mTOR inhibitor-based immunosuppression following kidney transplantation: a novel approach for tailored immunosuppressive therapy.
Kidney international 20051201
-
Rapamycin worsens renal function and intratubular cast formation in protein overload nephropathy.
Kidney international 20051201
-
Sirolimus-induced interstitial pneumonitis in a renal transplant patient.
Respiratory care 20051201
-
Drug-eluting coronary stents.
The New England journal of medicine 20051201
-
Time course of release of inflammatory markers after coronary stenting: comparison between bare metal stent and sirolimus-eluting stent.
Coronary artery disease 20051201
-
Drug-eluting coronary stents.
The New England journal of medicine 20051201
-
Drug-eluting coronary stents.
The New England journal of medicine 20051201
-
Drug-eluting coronary stents.
The New England journal of medicine 20051201
-
Drug-eluting coronary stents.
The New England journal of medicine 20051201
-
Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells.
Cancer research 20051201
-
Cypher versus taxus: are there differences?
Journal of interventional cardiology 20051201
-
Treatment of unprotected left main coronary artery stenosis in the drug-eluting stent era.
Journal of interventional cardiology 20051201
-
Should degenerated saphenous vein grafts routinely be sealed with drug-eluting stents?
Journal of interventional cardiology 20051201
-
Immunosuppressive treatment and progression of histologic lesions in kidney allografts.
Kidney international. Supplement 20051201
-
The hypoxic microenvironment of the skin contributes to Akt-mediated melanocyte transformation.
Cancer cell 20051201
-
Outcome of percutaneous hybrid coronary revascularization: bare metal stents jeopardize the benefit of sirolimus-eluting stents in the real world.
The Canadian journal of cardiology 20051201
-
Sirolimus: its role in nephrology.
Nephrology (Carlton, Vic.) 20051201
-
Sirolimus-eluting versus bare stents for bailout after suboptimal infrapopliteal angioplasty for critical limb ischemia: 6-month angiographic results from a nonrandomized prospective single-center study.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20051201
-
Sirolimus in cardiac transplantation: use as a primary immunosuppressant in calcineurin inhibitor-induced nephrotoxicity.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20051201
-
Bone morphogenetic protein-2-induced transformation involves the activation of mammalian target of rapamycin.
Molecular cancer research : MCR 20051201
-
Everolimus (certican) in heart transplantation: optimizing renal function through minimizing cyclosporine exposure.
Transplantation proceedings 20051201
-
Sirolimus conversion after liver transplantation: improvement in measured glomerular filtration rate after 2 years.
Transplantation proceedings 20051201
-
Late acute cardiac allograft rejection: new therapeutic options?
Transplantation proceedings 20051201
-
Late expression of nitroreductase in an oncolytic adenovirus sensitizes colon cancer cells to the prodrug CB1954.
Human gene therapy 20051201
-
Biomarkers for toxicodynamic monitoring of immunosuppressants: NMR-based quantitative metabonomics of the blood.
Therapeutic drug monitoring 20051201
-
Complete regression of visceral Kaposi's sarcoma after conversion to sirolimus.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20051201
-
[The safety and efficacy of Cypher drug-eluting stent: results from a six months follow-up study in patients with ST-segment elevation myocardial infarction].
Zhonghua xin xue guan bing za zhi 20051201
-
Drug-eluting stent: a review and update.
Vascular health and risk management 20051201
-
Glutamatergic regulation of the p70S6 kinase in primary mouse neurons.
The Journal of biological chemistry 20051118
-
mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events.
Cell 20051118
-
Comparison of effects of drug-eluting stents versus bare metal stents on plasma C-reactive protein levels.
The American journal of cardiology 20051115
-
Impact of diabetes mellitus on angiographic and clinical outcomes in the drug-eluting stents era.
The American journal of cardiology 20051115
-
Effect of sirolimus-eluting stent in diabetic patients with small coronary arteries (a SES-SMART substudy).
The American journal of cardiology 20051115
-
Impact of asymmetric stent expansion on neointimal hyperplasia following sirolimus-eluting stent implantation.
The American journal of cardiology 20051115
-
Proteinuria following a switch from calcineurin inhibitors to sirolimus.
Transplantation 20051115
-
Superior outcomes in renal transplantation after early cyclosporine withdrawal and sirolimus maintenance therapy, regardless of baseline renal function.
Transplantation 20051115
-
Anemia after late introduction of sirolimus may correlate with biochemical evidence of a chronic inflammatory state.
Transplantation 20051115
-
Sirolimus monotherapy: feasible immunosuppression for long-term follow-up of kidney transplantation--a pilot experience.
Transplantation 20051115
-
Post-transplantation proteinuria and sirolimus.
The New England journal of medicine 20051110
-
Drug-eluting stents: sirolimus and paclitaxel differentially affect cultured cells and injured arteries.
European journal of pharmacology 20051107
-
A systematic review and economic analysis of drug-eluting coronary stents available in Australia.
The Medical journal of Australia 20051107
-
PTEN-induction in U251 glioma cells decreases the expression of insulin-like growth factor binding protein-2.
Biochemical and biophysical research communications 20051104
-
A novel drug-eluting stent spray-coated with multi-layers of collagen and sirolimus.
Journal of controlled release : official journal of the Controlled Release Society 20051102
-
Role of oral rapamycin to prevent restenosis in patients with de novo lesions undergoing coronary stenting: results of the Argentina single centre study (ORAR trial).
Heart (British Cardiac Society) 20051101
-
Reduced cardiac hypertrophy in toll-like receptor 4-deficient mice following pressure overload.
Cardiovascular research 20051101
-
Long-term results in renal transplant patients with allograft dysfunction after switching from calcineurin inhibitors to sirolimus.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20051101
-
LDL-cholesterol predicts negative coronary artery remodelling in diabetic patients: an intravascular ultrasound study.
European heart journal 20051101
-
Protein turnover in cardiac cell growth and survival.
Cardiovascular research 20051101
-
Ca2+-dependent reduction of IK1 in rat ventricular cells: a novel paradigm for arrhythmia in heart failure?
Cardiovascular research 20051101
-
Protective effect of calcineurin inhibitors on acoustic injury of the cochlea.
Hearing research 20051101
-
Sirolimus-induced ulceration of the small bowel in islet transplant recipients: report of two cases.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051101
-
Impairment of renal function after islet transplant alone or islet-after-kidney transplantation using a sirolimus/tacrolimus-based immunosuppressive regimen.
Transplant international : official journal of the European Society for Organ Transplantation 20051101
-
Sirolimus-associated hepatotoxicity in the kidney graft recipient.
Transplant international : official journal of the European Society for Organ Transplantation 20051101
-
Inflammation and caspase activation in long-term renal ischemia/reperfusion injury and immunosuppression in rats.
Kidney international 20051101
-
Relationships between sirolimus dosing, concentration and outcomes in renal transplant recipients.
British journal of clinical pharmacology 20051101
-
Trimethoprim-sulphamethoxazole does not affect the pharmacokinetics of sirolimus in renal transplant recipients.
British journal of clinical pharmacology 20051101
-
Ex vivo rapamycin generates donor Th2 cells that potently inhibit graft-versus-host disease and graft-versus-tumor effects via an IL-4-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 20051101
-
Ng-MIP, a surface-exposed lipoprotein of Neisseria gonorrhoeae, has a peptidyl-prolyl cis/trans isomerase (PPIase) activity and is involved in persistence in macrophages.
Molecular microbiology 20051101
-
Paclitaxel-eluting stents in coronary artery disease.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20051101
-
Inflammatory reaction after sirolimus-eluting stent implant.
The Annals of thoracic surgery 20051101
-
Impact of intravascular ultrasound lesion characteristics on neointimal hyperplasia following sirolimus-eluting stent implantation.
The American journal of cardiology 20051101
-
Predictors of edge stenosis following sirolimus-eluting stent deployment (a quantitative intravascular ultrasound analysis from the SIRIUS trial).
The American journal of cardiology 20051101
-
Elevated glucose activates protein synthesis in cultured cardiac myocytes.
Metabolism: clinical and experimental 20051101
-
Darbepoetin alfa treatment for post-renal transplantation anemia during pregnancy.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20051101
-
Evaluation of four-year coronary artery response after sirolimus-eluting stent implantation using serial quantitative intravascular ultrasound and computer-assisted grayscale value analysis for plaque composition in event-free patients.
Journal of the American College of Cardiology 20051101
-
Treatment of in-stent restenosis with sirolimus-eluting-stents -- a six month clinical and angiographic follow-up.
Zeitschrift fur Kardiologie 20051101
-
Sirolimus-eluting stent treatment for complex proximal left anterior descending artery stenoses: 7-month clinical and angiographic results.
The Journal of invasive cardiology 20051101
-
Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck.
Cancer research 20051101
-
Rapamycin-coated expanded polytetrafluoroethylene bypass grafts exhibit decreased anastomotic neointimal hyperplasia in a porcine model.
Journal of vascular surgery 20051101
-
Improvement of renal dysfunction by conversion from calcineurin inhibitors to sirolimus after heart transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20051101
-
Mammalian target of rapamycin as a therapeutic target in leukemia.
Current molecular medicine 20051101
-
Mammalian target of rapamycin promotes vincristine resistance through multiple mechanisms independent of maintained glycolytic rate.
Molecular cancer research : MCR 20051101
-
[Six-month intravascular ultrasound follow-up of coronary bifurcation lesions treated with rapamycin-eluting stents: technical considerations].
Revista espanola de cardiologia 20051101
-
[Coronary artery aneurysm one year and five months after sirolimus-eluting stent placement].
Arquivos brasileiros de cardiologia 20051101
-
[Sirolimus-eluting vs paclitaxel-eluting stents -- the trials confirm differences in clinical outcome].
Kardiologia polska 20051101
-
Evaluation of the cost-effectiveness of sirolimus versus cyclosporin for immunosuppression after renal transplantation in the United Kingdom.
Clinical therapeutics 20051101
-
Individualization of immunosuppressive therapy: I. Sirolimus improves outcomes in African-American renal transplant recipients.
Transplantation proceedings 20051101
-
Rapamycin at six years can exhibit normal renal function without proteinuria or neoplasia after renal transplantation. A single-center experience.
Transplantation proceedings 20051101
-
Evolution of proteinuria after conversion from calcineurin inhibitors (CNI) to sirolimus (SRL) in renal transplant patients: a multicenter study.
Transplantation proceedings 20051101
-
Efficacy of conversion to sirolimus in posttransplantation Kaposi's sarcoma.
Transplantation proceedings 20051101
-
Rapamycin in lung transplantation.
Transplantation proceedings 20051101
-
Sirolimus as an alternative to anticalcineurin therapy in heart transplantation: experience of a single center.
Transplantation proceedings 20051101
-
[Drug eluting stents in 2005: have the initial expectations been met?].
Annales de cardiologie et d'angeiologie 20051101
-
[Comparison of the effects of rapamycin-eluting stent implantation and coronary artery bypass grafting in treatment of patients with multi-vessel coronary disease].
Zhonghua yi xue za zhi 20051026
-
RACK1 mRNA translation is regulated via a rapamycin-sensitive pathway and coordinated with ribosomal protein synthesis.
FEBS letters 20051024
-
Protein synthesis-independent plasticity mediates rapid and precise recovery of deprived eye responses.
Neuron 20051020
-
Impact of treatment of coronary artery disease with sirolimus-eluting stents on outcomes of diabetic and nondiabetic patients.
The American journal of cardiology 20051015
-
Predictors of outcome after sirolimus-eluting stent implantation for complex in-stent restenosis.
The American journal of cardiology 20051015
-
Maintenance immunosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies.
Transplantation 20051015
-
New-onset diabetes after kidney transplantation: an application of 2003 International Guidelines.
Transplantation 20051015
-
Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids.
Transplantation 20051015
-
Review of major clinical trials with mycophenolate mofetil in renal transplantation.
Transplantation 20051015
-
The impact of mycophenolate mofetil on long-term outcomes in kidney transplantation.
Transplantation 20051015
-
Malignancy after transplantation.
Transplantation 20051015
-
Attenuation of insulin-stimulated insulin receptor substrate-1 serine 307 phosphorylation in insulin resistance of type 2 diabetes.
The Journal of biological chemistry 20051014
-
Synergistic inhibition of human neuroblastoma-related angiogenesis by vinblastine and rapamycin.
Oncogene 20051013
-
[Everolimus].
Deutsche medizinische Wochenschrift (1946) 20051007
-
Tirofiban plus sirolimus-eluting stent vs abciximab plus bare-metal stent.
JAMA 20051005
-
Tirofiban plus sirolimus-eluting stent vs abciximab plus bare-metal stent.
JAMA 20051005
-
Randomized comparison of sirolimus-eluting stent versus standard stent for percutaneous coronary revascularization in diabetic patients: the diabetes and sirolimus-eluting stent (DIABETES) trial.
Circulation 20051004
-
Differential regulation of the p70 S6 kinase pathway by interferon alpha (IFNalpha) and imatinib mesylate (STI571) in chronic myelogenous leukemia cells.
Blood 20051001
-
Cell size reduction induced by inhibition of the mTOR/S6K-signaling pathway protects Jurkat cells from apoptosis.
Cell death and differentiation 20051001
-
Altered centrosomes in ataxia-telangiectasia cells and rapamycin-treated Chinese hamster cells.
Environmental and molecular mutagenesis 20051001
-
Insulin-like growth factor-I inhibits dexamethasone-induced proteolysis in cultured L6 myotubes through PI3K/Akt/GSK-3beta and PI3K/Akt/mTOR-dependent mechanisms.
The international journal of biochemistry & cell biology 20051001
-
Combination of imatinib with rapamycin or RAD001 acts synergistically only in Bcr-Abl-positive cells with moderate resistance to imatinib.
Leukemia 20051001
-
Rapamycin: an anti-cancer immunosuppressant?
Critical reviews in oncology/hematology 20051001
-
T-cadherin protects endothelial cells from oxidative stress-induced apoptosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051001
-
Glucose metabolism in renal transplant recipients: effect of calcineurin inhibitor withdrawal and conversion to sirolimus.
Journal of the American Society of Nephrology : JASN 20051001
-
[Late thrombosis of a drug-eluting coronary stent after antiplatelet therapy discontinuation].
Annales francaises d'anesthesie et de reanimation 20051001
-
Compensatory PI3-kinase/Akt/mTor activation regulates imatinib resistance development.
Leukemia 20051001
-
Concentration-controlled use of sirolimus associated with reduced exposure of cyclosporine in black recipients of primarily living renal allograft donors: 12-month results.
Clinical transplantation 20051001
-
Sirolimus-associated interstitial pneumonitis in solid organ transplant recipients.
Clinical transplantation 20051001
-
The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis.
Apoptosis : an international journal on programmed cell death 20051001
-
ISR II study: a long-term evaluation of sirolimus-eluting stent in the treatment of patients with in-stent restenotic native coronary artery lesions.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20051001
-
Sirolimus-eluting stents: safe and effective in the treatment of in-stent restenosis.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20051001
-
Comparison of pharmacokinetics of the sirolimus-eluting stent in Japanese patients with those in American patients.
Journal of cardiovascular pharmacology 20051001
-
Rapamycin attenuates atherosclerotic plaque progression in apolipoprotein E knockout mice: inhibitory effect on monocyte chemotaxis.
Journal of cardiovascular pharmacology 20051001
-
Involvement of c-Jun NH2 terminal kinase and p38MAPK in rapamycin-mediated inhibition of neointimal formation in rat carotid arteries.
Journal of cardiovascular pharmacology 20051001
-
Sirolimus-induced thrombotic microangiopathy is associated with decreased expression of vascular endothelial growth factor in kidneys.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051001
-
A randomized controlled trial of late conversion from CNI-based to sirolimus-based immunosuppression following renal transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051001
-
Three-year efficacy and safety results from a study of everolimus versus mycophenolate mofetil in de novo renal transplant patients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051001
-
Comparison of sirolimus with low-dose tacrolimus versus sirolimus-based calcineurin inhibitor-free regimen in live donor renal transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051001
-
Hypoxia inducible factor-1: a novel target for cancer therapy.
Anti-cancer drugs 20051001
-
Expression of proline-rich Akt-substrate PRAS40 in cell survival pathway and carcinogenesis.
Acta pharmacologica Sinica 20051001
-
The role of therapeutic monitoring of everolimus in solid organ transplantation.
Therapeutic drug monitoring 20051001
-
New drug-eluting stents, optimizing technique, and the problem of drug-eluting stent restenosis.
Minerva cardioangiologica 20051001
-
Pharmacokinetic interaction between verapamil and everolimus in healthy subjects.
British journal of clinical pharmacology 20051001
-
Thrombosis of sirolimus-eluting coronary stent in the postanesthesia care unit.
Anesthesia and analgesia 20051001
-
Angiographic and clinical outcomes of a pharmacokinetic study of sirolimus-eluting stents: lesson from restenosis cases.
Circulation journal : official journal of the Japanese Circulation Society 20051001
-
Sirolimus-eluting stent implantation in diabetic patients with multivessel coronary artery disease.
American heart journal 20051001
-
Pirfenidone inhibits obliterative airway disease in mouse tracheal allografts.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20051001
-
The Candida albicans vacuole is required for differentiation and efficient macrophage killing.
Eukaryotic cell 20051001
-
Inhibition of the mammalian target of rapamycin and the induction of cell cycle arrest in mantle cell lymphoma cells.
Haematologica 20051001
-
Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate-1/phosphatidylinositol 3-kinase cascade.
Molecular cancer therapeutics 20051001
-
Disruption of parallel and converging signaling pathways contributes to the synergistic antitumor effects of simultaneous mTOR and EGFR inhibition in GBM cells.
Neoplasia (New York, N.Y.) 20051001
-
[Experimental study on the effects of rapamycin in prevention of rat corneal allograft rejection].
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20051001
-
Potential role of mammalian target of rapamycin inhibitors in breast cancer therapy.
Clinical breast cancer 20051001
-
[Primary study of vasculogenic mimicry induced by hypoxia in epithelial ovarian carcinoma].
Zhonghua fu chan ke za zhi 20051001
-
[Drug-eluting stents: indications, limits and future development].
Archives des maladies du coeur et des vaisseaux 20051001
-
Sirolimus inhibits platelet-derived growth factor-induced collagen synthesis in rat vascular smooth muscle cells.
Transplantation proceedings 20051001
-
A pilot study of immunosuppression minimization after pancreas-kidney transplantation utilizing thymoglobulin induction and sirolimus maintenance therapy.
Transplantation proceedings 20051001
-
Experience with sirolimus for calcineurin minimization/elimination in pancreas-after-kidney transplantation.
Transplantation proceedings 20051001
-
Metabolic effect of sirolimus versus mycophenolate mofetil on pancreatic graft function in the early posttransplant period.
Transplantation proceedings 20051001
-
Diabetes and percutaneous coronary intervention in the setting of an acute coronary syndrome.
Diabetes & vascular disease research 20051001
-
[Sirolimus for rescue of recurrent acute rejection and diabetes mellitus after liver transplantation: report of one case].
Revista medica de Chile 20051001
-
Sirolimus: a new immunosuppressant.
The Journal of the Association of Physicians of India 20051001
-
[Advances on PI3K/Akt/mTOR signalling pathway in malignancies].
Zhonghua bing li xue za zhi = Chinese journal of pathology 20051001
-
Rapamycin, but not FK-506, increases endothelial tissue factor expression: implications for drug-eluting stent design.
Circulation 20050927
-
Low incidence of malignancy among sirolimus/cyclosporine-treated renal transplant recipients.
Transplantation 20050927
-
Comparison of steroid avoidance in tacrolimus/mycophenolate mofetil and tacrolimus/sirolimus combination in kidney transplantation monitored by surveillance biopsy.
Transplantation 20050927
-
mTOR inhibition and its effect on cancer in transplantation.
Transplantation 20050927
-
Lithium induces autophagy by inhibiting inositol monophosphatase.
The Journal of cell biology 20050926
-
Shp2 is required for protein kinase C-dependent phosphorylation of serine 307 in insulin receptor substrate-1.
The Journal of biological chemistry 20050923
-
The FK506 binding protein Fpr3 counteracts protein phosphatase 1 to maintain meiotic recombination checkpoint activity.
Cell 20050923
-
Late incomplete stent apposition after sirolimus-eluting stent implantation: a serial intravascular ultrasound analysis.
Journal of the American College of Cardiology 20050920
-
Overexpression of NBS1 contributes to transformation through the activation of phosphatidylinositol 3-kinase/Akt.
The Journal of biological chemistry 20050916
-
Tolerability of cyclosphosphamide and methotrexate induction immunosuppression in nonhuman primates.
Toxicology 20050915
-
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
Bioorganic & medicinal chemistry letters 20050915
-
Inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy.
Cancer research 20050915
-
Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis.
Genes & development 20050915
-
Late restenosis in patients receiving a polymer-coated sirolimus-eluting stent.
Annals of internal medicine 20050906
-
Effectiveness of sirolimus-eluting stent implantation for the treatment of ostial left anterior descending artery stenosis with intravascular ultrasound guidance.
Journal of the American College of Cardiology 20050906
-
Local perivascular delivery of anti-restenotic agents from a drug-eluting poly(epsilon-caprolactone) stent cuff.
Biomaterials 20050901
-
One year clinical follow up of paclitaxel eluting stents for acute myocardial infarction compared with sirolimus eluting stents.
Heart (British Cardiac Society) 20050901
-
A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein {beta} and NF-{kappa}B activity in Hodgkin and anaplastic large cell lymphomas.
Blood 20050901
-
CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium.
Cancer 20050901
-
Cardiovascular risk profile with the new immunosuppressive combinations after renal transplantation.
Journal of hypertension 20050901
-
Sirolimus in combination with tacrolimus is associated with worse renal allograft survival compared to mycophenolate mofetil combined with tacrolimus.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901
-
Proteinuria developing after clinical islet transplantation resolves with sirolimus withdrawal and increased tacrolimus dosing.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901
-
Analysis of exposure-response relationship in everolimus-cyclosporine combination regimen.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901
-
Therapeutic drug monitoring for everolimus in heart transplant recipients: flawed model or a model for future use?
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901
-
Bone metabolism in renal transplant patients treated with cyclosporine or sirolimus.
Transplant international : official journal of the European Society for Organ Transplantation 20050901
-
Immune cells in a heterotopic lamb-to-pig bronchial xenograft model.
Transplant international : official journal of the European Society for Organ Transplantation 20050901
-
Recurrence of in-stent restenosis in cardiac allograft vasculopathy following implantation of a sirolimus-eluting stent.
Transplant international : official journal of the European Society for Organ Transplantation 20050901
-
lipase-catalyzed regioselective esterification of rapamycin: synthesis of temsirolimus (CCI-779).
Organic letters 20050901
-
Simultaneous measurement of sirolimus and everolimus in whole blood by HPLC with ultraviolet detection.
Clinical chemistry 20050901
-
Effectiveness of the concomitant use of bivalirudin and drug-eluting stents (from the prospective, multicenter BivAlirudin and Drug-Eluting STents [ADEST] study).
The American journal of cardiology 20050901
-
Inhibition of PI-3 kinase/Akt/mTOR, but not calcineurin signaling, reverses insulin-like growth factor I-induced protection against glucose toxicity in cardiomyocyte contractile function.
The Journal of endocrinology 20050901
-
Re-stenosis of a sirolimus-coated stent in a heart transplant recipient with allograft vasculopathy.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050901
-
Sirolimus- and taxol-eluting stents differ towards intimal hyperplasia and re-endothelialization.
The Journal of invasive cardiology 20050901
-
Genetic analysis of the TOR pathway in Aspergillus nidulans.
Eukaryotic cell 20050901
-
Incremental cost-effectiveness of drug-eluting stents compared with a third-generation bare-metal stent in a real-world setting: randomised Basel Stent Kosten Effektivitäts Trial (BASKET).
Lancet (London, England) 20050901
-
An evaluation of the Abbott IMx sirolimus assay in relation to a high-performance liquid chromatography-ultraviolet method.
Annals of clinical biochemistry 20050901
-
Incidence and predictors of restenosis after sirolimus-eluting stent implantation in high-risk patients.
American heart journal 20050901
-
Update on drug-eluting coronary stents.
Expert review of cardiovascular therapy 20050901
-
How soon can a patient undergo noncardiac surgery after receiving a drug-eluting stent?
Cleveland Clinic journal of medicine 20050901
-
[Molecular targeted therapy for malignant brain tumors].
Nihon rinsho. Japanese journal of clinical medicine 20050901
-
Percutaneous treatment of the left main coronary artery ostial obstruction following aortic valve replacement.
Italian heart journal : official journal of the Italian Federation of Cardiology 20050901
-
Sirolimus as primary immunosuppression agent in kidney transplant recipients: Akdeniz University experience.
Transplantation proceedings 20050901
-
Early acute rejection episodes in renal transplantation in relation to immunosuppression protocols: an audit of 100 cases.
Transplantation proceedings 20050901
-
Observations on quadruple immunosuppression maintenance therapy using rapamycin, low-dose cyclosporine, mycophenolate mofetil, and prednisone following ATG induction.
Transplantation proceedings 20050901
-
[Sirolimus-eluting stent for in-stent restenosis treatment: single center results in an unselected study population].
Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20050901
-
Active stents in diabetic patients.
Diabetes & metabolism 20050901
-
Pharmacokinetics of sirolimus in Thai healthy volunteers.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20050901
-
Kaposi's sarcoma after renal transplantation.
The New England journal of medicine 20050825
-
Kaposi's sarcoma after renal transplantation.
The New England journal of medicine 20050825
-
Images in cardiovascular medicine. Giant coronary aneurysm formation after sirolimus-eluting stent implantation in Kawasaki disease.
Circulation 20050823
-
Enhanced radiation damage of tumor vasculature by mTOR inhibitors.
Oncogene 20050818
-
Sirolimus-eluting and paclitaxel-eluting stents for coronary revascularization.
The New England journal of medicine 20050818
-
Paclitaxel-eluting or sirolimus-eluting stents to prevent restenosis in diabetic patients.
The New England journal of medicine 20050818
-
Healing Achilles--sirolimus versus paclitaxel.
The New England journal of medicine 20050818
-
Sirolimus-eluting stents vs paclitaxel-eluting stents in patients with coronary artery disease: meta-analysis of randomized trials.
JAMA 20050817
-
[Short and long-term therapeutic effects of rapamycin-eluting stent and paclitaxel-eluting stent in treatment of coronary disease with complicated lesions].
Zhonghua yi xue za zhi 20050817
-
Bifurcation coronary lesions treated with the 'crush' technique: an intravascular ultrasound analysis.
Journal of the American College of Cardiology 20050816
-
Clinical and angiographic outcome after implantation of drug-eluting stents in bifurcation lesions with the crush stent technique: importance of final kissing balloon post-dilation.
Journal of the American College of Cardiology 20050816
-
Rapamycin stimulates apoptosis of childhood acute lymphoblastic leukemia cells.
Blood 20050815
-
A prospective, randomized trial of tacrolimus in combination with sirolimus or mycophenolate mofetil in kidney transplantation: results at 1 year.
Transplantation 20050815
-
Robust tolerance to fully allogeneic islet transplants achieved by chimerism with minimal conditioning.
Transplantation 20050815
-
Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition.
Cancer research 20050815
-
Novel fusion protein approach for efficient high-throughput screening of small molecule-mediating protein-protein interactions in cells and living animals.
Cancer research 20050815
-
[Treatment and prevention of restenosis after percutaneous coronary intervention. Balloons, stents, radioactive rays and drug-releasing stents].
Ugeskrift for laeger 20050815
-
Phase II study of temsirolimus (CCI-779), a novel inhibitor of mTOR, in heavily pretreated patients with locally advanced or metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050810
-
Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050810
-
Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050810
-
4E-binding protein phosphorylation and eukaryotic initiation factor-4E release are required for airway smooth muscle hypertrophy.
American journal of respiratory cell and molecular biology 20050801
-
Resolution of renal allograft-associated post-transplant lymphoproliferative disorder with the introduction of sirolimus.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050801
-
Late thrombosis of sirolimus-eluting stents following noncardiac surgery.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050801
-
Everolimus treatment downregulates renocortical cyclooxygenase-2 expression in the rat kidney.
British journal of pharmacology 20050801
-
Selective versus exclusive use of sirolimus-eluting stent implantation in multivessel coronary artery disease.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050801
-
Late thrombosis following treatment of in-stent restenosis with drug-eluting stents after discontinuation of antiplatelet therapy.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050801
-
Prevention of restenosis by a novel drug-eluting stent system with a dose-adjustable, polymer-free, on-site stent coating.
European heart journal 20050801
-
Impact of sirolimus-eluting stents on outcomes of patients treated for acute myocardial infarction by primary angioplasty.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050801
-
Pre-transplant IFN-gamma ELISPOTs are associated with post-transplant renal function in African American renal transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050801
-
Adding sirolimus to tacrolimus-based immunosuppression in pediatric renal transplant recipients reduces tacrolimus exposure.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050801
-
Islet transplantation in type 1 diabetes mellitus using cultured islets and steroid-free immunosuppression: Miami experience.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050801
-
Use of drug-eluting stents for the treatment of in-stent restenosis in routine clinical practice.
Coronary artery disease 20050801
-
An expanding role for mTOR in cancer.
Trends in molecular medicine 20050801
-
Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme.
Investigational new drugs 20050801
-
Gas6 induces Akt/mTOR-mediated mesangial hypertrophy in diabetic nephropathy.
Kidney international 20050801
-
Mycophenolate mofetil in islet cell transplant: variable pharmacokinetics but good correlation between total and unbound concentrations.
Journal of clinical pharmacology 20050801
-
A phase I multiple-dose escalation study characterizing pharmacokinetics and safety of ABT-578 in healthy subjects.
Journal of clinical pharmacology 20050801
-
Generalized, pruritic, ulcerating maculopapular rash necessitating cessation of sirolimus in a liver transplantation patient.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20050801
-
Sirolimus-related toxicity in stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050801
-
Sirolimus in combination with tacrolimus and corticosteroids for the treatment of resistant chronic graft-versus-host disease.
British journal of haematology 20050801
-
Sirolimus in pediatric solid organ transplantation.
Pediatric transplantation 20050801
-
Sirolimus in pediatric patients: results in the first 6 months post-renal transplant.
Pediatric transplantation 20050801
-
Cardiac tamponade in a pediatric renal transplant recipient on sirolimus therapy.
Pediatric transplantation 20050801
-
Comparison of short- (one month) and long- (twelve months) term outcomes of sirolimus- versus paclitaxel-eluting stents in 293 consecutive patients with diabetes mellitus (from the RESEARCH and T-SEARCH registries).
The American journal of cardiology 20050801
-
RAD001 (everolimus) improves the efficacy of replicating adenoviruses that target colon cancer.
Cancer research 20050801
-
Sirolimus-eluting stents for treatment of complex bypass graft disease: insights from the SECURE registry.
The Journal of invasive cardiology 20050801
-
Prospective native coronary artery stenosis treated with sirolimus-eluting stent (ONASSIS) registry--acute results and mid-term outcomes: a single-center experience.
The Journal of invasive cardiology 20050801
-
One-year clinical outcome after coronary stenting of very small vessels using 2.25 mm sirolimus- and paclitaxel-eluting stents: a comparison between the RESEARCH and T-SEARCH registries.
The Journal of invasive cardiology 20050801
-
Balloon alignment T-stenting for bifurcation coronary artery disease using the sirolimus-eluting stent.
The Journal of invasive cardiology 20050801
-
Sirolimus-eluting stent implantation and beta-irradiation for the treatment of in-stent restenotic lesions: comparison of underlying mechanisms of acute gain and late loss as assessed by volumetric intravascular ultrasound.
American heart journal 20050801
-
[Drug eluting stents: from evidence based medicine to clinical practice].
Annales de cardiologie et d'angeiologie 20050801
-
Pim family kinases enhance tumor growth of prostate cancer cells.
Molecular cancer research : MCR 20050801
-
Successful use of the new immune-suppressor sirolimus in IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome).
The Journal of pediatrics 20050801
-
A high-throughput method for screening of rapamycin-producing strains of Streptomyces hygroscopicus by cultivation in 96-well microtiter plates.
Biotechnology letters 20050801
-
[Improved outcome with sirolimus-cyclosporine regimen in high-risk renal transplant recipients].
Orvosi hetilap 20050731
-
Everolimus versus mycophenolate mofetil in the prevention of rejection in de novo renal transplant recipients: a 3-year randomized, multicenter, phase III study.
Transplantation 20050727
-
Sirolimus may not cause neurotoxicity in kidney and liver transplant recipients.
Neurology 20050726
-
Mutasynthesis of rapamycin analogues through the manipulation of a gene governing starter unit biosynthesis.
Angewandte Chemie (International ed. in English) 20050725
-
Methionine sulfoximine treatment and carbon starvation elicit Snf1-independent phosphorylation of the transcription activator Gln3 in Saccharomyces cerevisiae.
The Journal of biological chemistry 20050722
-
Antiproliferative profile of sirolimus and mycophenolate mofetil: impact of the SI/MPL ratio.
International journal of cardiology 20050720
-
Sirolimus-eluting stents associated with paradoxic coronary vasoconstriction.
Journal of the American College of Cardiology 20050719
-
Endothelial dysfunction after sirolimus-eluting stent placement.
Journal of the American College of Cardiology 20050719
-
Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase.
The Journal of biological chemistry 20050715
-
Body weight alterations under early corticosteroid withdrawal and chronic corticosteroid therapy with modern immunosuppression.
Transplantation 20050715
-
Differential effect of calcineurin inhibitors, anti-CD25 antibodies and rapamycin on the induction of FOXP3 in human T cells.
Transplantation 20050715
-
Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 20050715
-
Regulation of the phosphorylation and integrity of protein synthesis initiation factor eIF4GI and the translational repressor 4E-BP1 by p53.
Oncogene 20050714
-
Differential response of delayed healing and persistent inflammation at sites of overlapping sirolimus- or paclitaxel-eluting stents.
Circulation 20050712
-
Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase.
The Journal of biological chemistry 20050708
-
Amino acid signaling through the mammalian target of rapamycin (mTOR) pathway: Role of glutamine and of cell shrinkage.
Journal of cellular physiology 20050701
-
Drug-eluting stents compared with thin-strut bare stents for the reduction of restenosis: a prospective, randomized trial.
European heart journal 20050701
-
Shiga toxins activate translational regulation pathways in intestinal epithelial cells.
Cellular signalling 20050701
-
Effects of sirolimus on mesangial cell cholesterol homeostasis: a novel mechanism for its action against lipid-mediated injury in renal allografts.
American journal of physiology. Renal physiology 20050701
-
Follicle-stimulating hormone activates p70 ribosomal protein S6 kinase by protein kinase A-mediated dephosphorylation of Thr 421/Ser 424 in primary Sertoli cells.
Molecular endocrinology (Baltimore, Md.) 20050701
-
A novel class of dual-family immunophilins.
The Journal of biological chemistry 20050701
-
Rapamycin ameliorates proteinuria-associated tubulointerstitial inflammation and fibrosis in experimental membranous nephropathy.
Journal of the American Society of Nephrology : JASN 20050701
-
Modulation of insulin action by dietary proteins and amino acids: role of the mammalian target of rapamycin nutrient sensing pathway.
Current opinion in clinical nutrition and metabolic care 20050701
-
Calcineurin inhibitor withdrawal from sirolimus-based therapy in kidney transplantation: a systematic review of randomized trials.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050701
-
Rapamycin: a new string to the antiproteinuric bow?
Journal of the American Society of Nephrology : JASN 20050701
-
Glycogen autophagy in the liver and heart of newborn rats. The effects of glucagon, adrenalin or rapamycin.
Histology and histopathology 20050701
-
Phosphotidylinositol-3 kinase-mediated signals in mice immunized with the 57 kDa major antigenic outer-membrane protein of Shigella dysenteriae type 1.
Journal of medical microbiology 20050701
-
Influence of everolimus on steady-state pharmacokinetics of cyclosporine in maintenance renal transplant patients.
Journal of clinical pharmacology 20050701
-
Rapamycin and FK506 reduce skeletal muscle voltage sensor expression and function.
Cell calcium 20050701
-
Roles of deletion and regulation in creating mixed chimerism and allograft tolerance using a nonlymphoablative irradiation-free protocol.
Journal of immunology (Baltimore, Md. : 1950) 20050701
-
Stent-based delivered anti-proliferative drugs in the prevention of coronary stent restenosis.
Current medicinal chemistry. Cardiovascular and hematological agents 20050701
-
Sirolimus and thrombotic microangiopathy after allogeneic hematopoietic stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050701
-
The TOR and EGO protein complexes orchestrate microautophagy in yeast.
Molecular cell 20050701
-
The efficacy of sirolimus-eluting stents versus bare metal stents for diabetic patients undergoing elective percutaneous coronary intervention.
The Journal of invasive cardiology 20050701
-
Evolving use of drug-eluting stents in diabetic patients.
The Journal of invasive cardiology 20050701
-
Higher exposure to mycophenolic acid with sirolimus than with cyclosporine cotreatment.
Clinical pharmacology and therapeutics 20050701
-
[Drug-eluting stents and other anti-restenosis devices].
Revista espanola de cardiologia 20050701
-
Cilomilast, tacrolimus and rapamycin modulate dendritic cell function in the elicitation phase of allergic contact dermatitis.
The British journal of dermatology 20050701
-
Control of advanced and refractory acute myelogenous leukaemia with sirolimus-based non-myeloablative allogeneic stem cell transplantation.
British journal of haematology 20050701
-
Moving beyond the cost per quality-adjusted life year: modelling the budgetary impact and clinical outcomes associated with the use of sirolimus-eluting stents.
The Canadian journal of cardiology 20050701
-
Modulation of tissue factor expression by rapamycin and FK-506 in lipopolysaccharide-stimulated human mononuclear cells and serum-stimulated aortic smooth muscle cells.
Thrombosis and haemostasis 20050701
-
Angiotensin IV enhances phosphorylation of 4EBP1 by multiple signaling events in lung endothelial cells.
Molecular and cellular biochemistry 20050701
-
Late angiographic stent thrombosis (LAST) events with drug-eluting stents.
Journal of the American College of Cardiology 20050621
-
Synergistic growth inhibition by Iressa and Rapamycin is modulated by VHL mutations in renal cell carcinoma.
British journal of cancer 20050620
-
Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells.
Blood 20050615
-
Activation of protein synthesis in cardiomyocytes by the hypertrophic agent phenylephrine requires the activation of ERK and involves phosphorylation of tuberous sclerosis complex 2 (TSC2).
The Biochemical journal 20050615
-
TCR engagement increases hypoxia-inducible factor-1 alpha protein synthesis via rapamycin-sensitive pathway under hypoxic conditions in human peripheral T cells.
Journal of immunology (Baltimore, Md. : 1950) 20050615
-
Recombinant p21 protein inhibits lymphocyte proliferation and transcription factors.
Journal of immunology (Baltimore, Md. : 1950) 20050615
-
Comparison of effectiveness of sirolimus-eluting stents versus bare metal stents for percutaneous coronary intervention in patients at high risk for coronary restenosis or clinical adverse events.
The American journal of cardiology 20050615
-
Risk of thrombosis with the use of sirolimus-eluting stents for percutaneous coronary intervention (from registry and clinical trial data).
The American journal of cardiology 20050615
-
Antitumor activity of rapamycin in a transgenic mouse model of ErbB2-dependent human breast cancer.
Cancer research 20050615
-
A crevice adjoining the ribosome tunnel: hints for cotranslational folding.
FEBS letters 20050613
-
Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1alpha.
The Journal of biological chemistry 20050610
-
Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells.
The Journal of biological chemistry 20050603
-
Rapamycin induces tumor-specific thrombosis via tissue factor in the presence of VEGF.
Blood 20050601
-
Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival.
Blood 20050601
-
Rapamycin inhibits fibronectin-induced migration of the human arterial smooth muscle line (E47) through the mammalian target of rapamycin.
American journal of physiology. Heart and circulatory physiology 20050601
-
Estimation of pharmacokinetic parameters from non-compartmental variables using Microsoft Excel.
Computers in biology and medicine 20050601
-
Long-term treatment of bile duct-ligated rats with rapamycin (sirolimus) significantly attenuates liver fibrosis: analysis of the underlying mechanisms.
The Journal of pharmacology and experimental therapeutics 20050601
-
Identification of mTOR as a novel bifunctional target in chronic myeloid leukemia: dissection of growth-inhibitory and VEGF-suppressive effects of rapamycin in leukemic cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050601
-
Mycotic aneurysm of left anterior descending artery after sirolimus-eluting stent implantation: a case report.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050601
-
Immediate and mid-term outcomes of sirolimus-eluting stent implantation for chronic total occlusions.
European heart journal 20050601
-
Drug-eluting stents for chronic total occlusions make sense, but it is too early to close the discussion.
European heart journal 20050601
-
Effect of the immunosuppressive regime of Edmonton protocol on the long-term in vitro insulin secretion from islets of two different species and age categories.
Toxicology in vitro : an international journal published in association with BIBRA 20050601
-
The FK506-binding protein of the malaria parasite, Plasmodium falciparum, is a FK506-sensitive chaperone with FK506-independent calcineurin-inhibitory activity.
Molecular and biochemical parasitology 20050601
-
Activation of CREB by tauroursodeoxycholic acid protects cholangiocytes from apoptosis induced by mTOR inhibition.
Hepatology (Baltimore, Md.) 20050601
-
Early cyclosporine a withdrawal in kidney-transplant recipients receiving sirolimus prevents progression of chronic pathologic allograft lesions.
The Journal of urology 20050601
-
Clinical outcomes after sirolimus-eluting stent implantation for de novo saphenous vein graft lesions.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050601
-
Rapamycin inhibits human renal epithelial cell proliferation: effect on cyclin D3 mRNA expression and stability.
Kidney international 20050601
-
BOOP is common in cardiac transplant recipients switched from a calcineurin inhibitor to sirolimus.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050601
-
Everolimus alters the bronchoalveolar lavage and endobronchial biopsy immunologic profile post-human lung transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050601
-
A prospective randomized trial of steroid-free maintenance regimens in kidney transplant recipients--an interim analysis.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050601
-
Very late thrombosis after implantation of sirolimus eluting stent.
Heart (British Cardiac Society) 20050601
-
Fatal infection after rapamycin eluting coronary stent implantation.
Heart (British Cardiac Society) 20050601
-
A paclitaxel coated stent used for in-stent restenosis within a sirolimus coated stent fails to protect against recurrent restenosis.
Heart (British Cardiac Society) 20050601
-
Differential regulation of smooth muscle markers in human bone marrow-derived mesenchymal stem cells.
Journal of hypertension 20050601
-
Who let the bugs in?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050601
-
Underexpansion of sirolimus-eluting stents: incidence and relationship to delivery pressure.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050601
-
Stent-based delivery of ABT-578 via a phosphorylcholine surface coating reduces neointimal formation in the porcine coronary model.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050601
-
Incidence and predictors of target vessel revascularization and clinical event rates of the sirolimus-eluting coronary stent (results from the prospective multicenter German Cypher Stent Registry).
The American journal of cardiology 20050601
-
CEDIA sirolimus assay compared with HPLC-MS/MS and HPLC-UV in transplant recipient specimens.
Therapeutic drug monitoring 20050601
-
An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways.
Nature methods 20050601
-
Sirolimus for solid organ transplantation in children.
Pediatric transplantation 20050601
-
Replacing calcineurin inhibitors with mTOR inhibitors in children.
Pediatric transplantation 20050601
-
Rapamycin inhibits human in stent restenosis vascular smooth muscle cells independently of pRB phosphorylation and p53.
Cardiovascular research 20050601
-
Sirolimus-eluting stent for in-stent restenosis of left main coronary artery in takayasu arteritis.
Circulation journal : official journal of the Japanese Circulation Society 20050601
-
Adverse effects of local or systemic application of rapamycin for the prevention of neointimal hyperplasia.
The Annals of thoracic surgery 20050601
-
Drug eluting stents in 2005.
Heart (British Cardiac Society) 20050601
-
The efficacy of sirolimus in the treatment of patients with refractory uveitis.
The British journal of ophthalmology 20050601
-
Angiographic and clinical outcome for the treatment of in-stent restenosis with sirolimus-eluting stent compared to vascular brachytherapy.
Zeitschrift fur Kardiologie 20050601
-
Short-term rapamycin for inhibition of neointima formation after balloon-mediated aortic injury in rats: is there a window of opportunity for systemic prophylaxis of restenosis?
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20050601
-
Farnesyltransferase inhibitors reverse altered growth and distribution of actin filaments in Tsc-deficient cells via inhibition of both rapamycin-sensitive and -insensitive pathways.
Molecular cancer therapeutics 20050601
-
Drug coated stents for carotid intervention.
The Journal of cardiovascular surgery 20050601
-
Delayed renal graft function: the influence of immunosuppression.
Transplantation proceedings 20050601
-
Toward the definition of immunosuppressive regimens with antitumor activity.
Transplantation proceedings 20050601
-
Successful use of sirolimus in a patient with bulky ovarian metastasis of hepatocellular carcinoma after liver transplantation.
Transplantation proceedings 20050601
-
De novo immunosuppression with sirolimus and tacrolimus in heart transplant recipients compared with cyclosporine and mycophenolate mofetil: a one-year follow-up analysis.
Transplantation proceedings 20050601
-
Cyclosporine and sirolimus interaction in a kidney transplant patient.
Transplantation proceedings 20050601
-
[Advances in adjunctive pharmacological therapy for percutaneous coronary interventions].
Revista espanola de cardiologia 20050601
-
Placement of a sirolimus-coated stent in the distal left internal mammary artery of an 8-year-old boy.
The Journal of invasive cardiology 20050601
-
The present and future of drug-eluting stents.
Italian heart journal : official journal of the Italian Federation of Cardiology 20050601
-
Restenosis treatment in the drug-eluting stent era.
Italian heart journal : official journal of the Italian Federation of Cardiology 20050601
-
Rapamycin pre-treatment preserves viability, ATP level and catabolic capacity during carbon starvation of Saccharomyces cerevisiae.
Yeast (Chichester, England) 20050601
-
[Experimental study of Mytrolimus-eluting stents on preventing restenosis in porcine coronary model].
Zhonghua xin xue guan bing za zhi 20050601
-
Drug eluting stents in acute myocardial infarction.
Panminerva medica 20050601
-
The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability.
The Journal of biological chemistry 20050527
-
Target of rapamycin-dependent activation of S6 kinase is a central step in the transduction of nutritional signals during egg development in a mosquito.
The Journal of biological chemistry 20050527
-
The rapamycin analog CCI-779 is a potent inhibitor of pancreatic cancer cell proliferation.
Biochemical and biophysical research communications 20050527
-
Response to 'Exceptional circumstances and heart transplantation' letter.
The New Zealand medical journal 20050520
-
Withdrawal of immunosuppression contributing to the remission of malignant melanoma: a case report.
Cancer immunity 20050519
-
Multiple overlapping drug-eluting stents to treat diffuse disease of the left anterior descending coronary artery.
Journal of the American College of Cardiology 20050517
-
Cyclosporin A and tacrolimus, but not rapamycin, inhibit MHC-restricted antigen presentation pathways in dendritic cells.
Blood 20050515
-
Ryanodine receptor subtype 2 encodes Ca2+ oscillations activated by acetylcholine via the M2 muscarinic receptor/cADP-ribose signalling pathway in duodenum myocytes.
Journal of cell science 20050515
-
Comparison of thrombosis and restenosis risk from stent length of sirolimus-eluting stents versus bare metal stents.
The American journal of cardiology 20050515
-
Drug-eluting stents versus bare metal stents in percutaneous coronary interventions (a meta-analysis).
The American journal of cardiology 20050515
-
Comparison of C-reactive protein levels before and after coronary stenting and restenosis among patients treated with sirolimus-eluting versus bare metal stents.
The American journal of cardiology 20050515
-
Intravascular ultrasound stent area of sirolimus-eluting stents and its impact on late outcome.
The American journal of cardiology 20050515
-
Reduction in calcineurin inhibitor exposure and maintenance of effective immunosuppression: clinical experience with everolimus (Certican).
Transplantation 20050515
-
Introducing everolimus (Certican) in organ transplantation: an overview of preclinical and early clinical developments.
Transplantation 20050515
-
Concentration-controlled everolimus (Certican): combination with reduced dose calcineurin inhibitors.
Transplantation 20050515
-
Clinical experience with everolimus (Certican): optimizing dose and tolerability.
Transplantation 20050515
-
Clinical experience with everolimus (Certican) in elderly recipients: the 'old-for-old' concept.
Transplantation 20050515
-
Clinical experience with everolimus (Certican) in young renal transplant recipients.
Transplantation 20050515
-
Clinical experience with everolimus (Certican): a summary.
Transplantation 20050515
-
Sourcing a chemical succession for cyclosporin from parasites and human pathogens.
Drug discovery today 20050515
-
The efficacy of sirolimus- and paclitaxel-eluting stents: a meta-analysis of randomized controlled trials.
The Canadian journal of cardiology 20050515
-
Four-year angiographic and intravascular ultrasound follow-up of patients treated with sirolimus-eluting stents.
Circulation 20050510
-
Insulin stimulates postsynaptic density-95 protein translation via the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway.
The Journal of biological chemistry 20050506
-
Rapamycin induces apoptosis of JN-DSRCT-1 cells by increasing the Bax : Bcl-xL ratio through concurrent mechanisms dependent and independent of its mTOR inhibitory activity.
Oncogene 20050505
-
Tirofiban and sirolimus-eluting stent vs abciximab and bare-metal stent for acute myocardial infarction: a randomized trial.
JAMA 20050504
-
Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents.
JAMA 20050504
-
Drug-eluting stents in acute myocardial infarction: is science catching up with practice?
JAMA 20050504
-
Catalase induced expression of inflammatory mediators via activation of NF-kappaB, PI3K/AKT, p70S6K, and JNKs in BV2 microglia.
Cellular signalling 20050501
-
Trans-10,cis-12 CLA increases adipocyte lipolysis and alters lipid droplet-associated proteins: role of mTOR and ERK signaling.
Journal of lipid research 20050501
-
Sirolimus rescue of renal failure in children after combined liver-kidney transplantation.
Pediatric nephrology (Berlin, Germany) 20050501
-
Combination therapy with sirolimus (rapamycin) and tacrolimus (FK-506) in treatment of refractory minimal change nephropathy, a clinical case report.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050501
-
Effect of a fermented ginseng extract, BST204, on the expression of cyclooxygenase-2 in murine macrophages.
International immunopharmacology 20050501
-
Role of mammalian target of rapamycin signaling in compensatory renal hypertrophy.
Journal of the American Society of Nephrology : JASN 20050501
-
Simultaneous kissing drug-eluting stent technique for percutaneous treatment of bifurcation lesions in large-size vessels.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050501
-
Warfarin or low-molecular-weight heparin therapy does not prolong pig-to-primate cardiac xenograft function.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050501
-
IDEC-131 (anti-CD154), sirolimus and donor-specific transfusion facilitate operational tolerance in non-human primates.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050501
-
Rapamycin successfully treats post-transplant autoimmune hepatitis.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050501
-
Preservation of renal structure and function at 2 years without calcineurin inhibitor use.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050501
-
Effect of different immunosuppressive therapies on the lipid pattern in kidney-transplanted rats.
Transplant international : official journal of the European Society for Organ Transplantation 20050501
-
Inter-laboratory differences in sirolimus results from six sirolimus testing centers using HPLC tandem mass spectrometry (LC/MS/MS).
Clinica chimica acta; international journal of clinical chemistry 20050501
-
Blood concentrations of everolimus are markedly increased by ketoconazole.
Journal of clinical pharmacology 20050501
-
IL-2 increases human telomerase reverse transcriptase activity transcriptionally and posttranslationally through phosphatidylinositol 3'-kinase/Akt, heat shock protein 90, and mammalian target of rapamycin in transformed NK cells.
Journal of immunology (Baltimore, Md. : 1950) 20050501
-
Inhibition of mammalian target of rapamycin potentiates thrombin-induced intercellular adhesion molecule-1 expression by accelerating and stabilizing NF-kappa B activation in endothelial cells.
Journal of immunology (Baltimore, Md. : 1950) 20050501
-
Insulin and IGF-I stimulate the formation of the eukaryotic initiation factor 4F complex and protein synthesis in C2C12 myotubes independent of availability of external amino acids.
The Journal of endocrinology 20050501
-
PWT-458, a novel pegylated-17-hydroxywortmannin, inhibits phosphatidylinositol 3-kinase signaling and suppresses growth of solid tumors.
Cancer biology & therapy 20050501
-
Mucositis after allogeneic hematopoietic stem cell transplantation: a cohort study of methotrexate- and non-methotrexate-containing graft-versus-host disease prophylaxis regimens.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050501
-
A fast and simple high-performance liquid chromatography/mass spectrometry method for simultaneous measurement of whole blood tacrolimus and sirolimus.
Archives of pathology & laboratory medicine 20050501
-
Use of a sirolimus-eluting stent to treat failure of a nonpolymer release paclitaxel-eluting stent implanted for in-stent restenosis.
The Journal of invasive cardiology 20050501
-
Replicating oncolytic virus therapeutics - Third International Meeting.
IDrugs : the investigational drugs journal 20050501
-
Sirolimus does double duty after organ transplantation.
The Lancet. Oncology 20050501
-
Clinical and cost-effectiveness of newer immunosuppressive regimens in renal transplantation: a systematic review and modelling study.
Health technology assessment (Winchester, England) 20050501
-
Effects of calcineurin inhibitors on sirolimus pharmacokinetics during staggered administration in renal transplant recipients.
Pharmacotherapy 20050501
-
Inhibiting phosphoinositide 3-kinases.
Cancer biology & therapy 20050501
-
Preservation of renal function after heart transplantation: initial single-center experience with sirolimus.
Transplantation proceedings 20050501
-
Lipid metabolism in renal transplant patients receiving tacrolimus/sirolimus combination therapy.
Transplantation proceedings 20050501
-
Effects of rapamycin on the arterial inflammatory response in atherosclerotic plaques in Apo-E knockout mice.
Transplantation proceedings 20050501
-
Successful conversion to rapamycin for calcineurin inhibitor-related neurotoxicity following liver transplantation.
Transplantation proceedings 20050501
-
Gonadal function and immunosuppressive therapy after renal transplantation.
Transplantation proceedings 20050501
-
Severe hearing loss after liver transplantation.
Transplantation proceedings 20050501
-
[Impact of coronary sirolimus-eluting stents on long-term outcome in diabetic patients].
Zhonghua xin xue guan bing za zhi 20050501
-
[Clinical and angiographic follow-up study of sirolimus-eluting stent for treatment of in-stent restenosis].
Zhonghua xin xue guan bing za zhi 20050501
-
[Rapamycin].
Nihon rinsho. Japanese journal of clinical medicine 20050501
-
Rapamycin ameliorates experimental autoimmune myocarditis.
International heart journal 20050501
-
Assessment of microvascular perfusion changes in a rat breast tumor model using SonoVue to monitor the effects of different anti-angiogenic therapies.
Academic radiology 20050501
-
Delayed occurrence of restenosis in drug eluting stents: an evidence of delayed healing.
The Journal of the Association of Physicians of India 20050501
-
TOR kinase pathway and 14-3-3 proteins regulate glucose-induced expression of HXT1, a yeast low-affinity glucose transporter.
Yeast (Chichester, England) 20050430
-
Effects of immunosuppressants on induction of regulatory cells after intratracheal delivery of alloantigen.
Transplantation 20050427
-
The effect of 2-gram versus 1-gram concentration controlled mycophenolate mofetil on renal transplant outcomes using sirolimus-based calcineurin inhibitor drug-free immunosuppression.
Transplantation 20050427
-
Immunosuppressive therapy with everolimus can be associated with potentially life-threatening lingual angioedema.
Transplantation 20050427
-
Impact of sirolimus on early graft function after deceased-donor kidney transplantation.
Transplantation 20050427
-
Elucidating the substrate specificity and condensation domain activity of FkbP, the FK520 pipecolate-incorporating enzyme.
Biochemistry 20050426
-
Letter regarding article by Sawhney et al, 'treatment of left anterior descending coronary artery disease with sirolimus-eluting stents'.
Circulation 20050426
-
Effectiveness and safety of sirolimus-eluting stents in the treatment of restenosis after coronary stent placement.
Circulation 20050426
-
Zinc induces neurofilament phosphorylation independent of p70 S6 kinase in N2a cells.
Neuroreport 20050425
-
The yeast eIF4E-associated protein Eap1p attenuates GCN4 translation upon TOR-inactivation.
FEBS letters 20050425
-
[Hemosiderophages in respiratory secretions. Biological significance and clinical utility].
Medicina clinica 20050423
-
Activation of a phytopathogenic bacterial effector protein by a eukaryotic cyclophilin.
Science (New York, N.Y.) 20050422
-
Pharmacokinetics of the immunosuppressant everolimus in maintenance renal transplant patients.
European journal of medical research 20050420
-
Cost-effectiveness of drug-eluting stents: if only all things were equal.
The Medical journal of Australia 20050418
-
Phosphorylated osteopontin promotes migration of human choriocarcinoma cells via a p70 S6 kinase-dependent pathway.
Journal of cellular biochemistry 20050415
-
Complete remission of postransplant lung metastases from hepatocellular carcinoma under therapy with sirolimus and mycophenolate mofetil.
Transplantation 20050415
-
Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ras.
Cancer research 20050415
-
Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors.
Cancer research 20050415
-
The role of p70S6K in hepatic stellate cell collagen gene expression and cell proliferation.
The Journal of biological chemistry 20050408
-
Adjusted indirect comparison of intracoronary drug-eluting stents: evidence from a metaanalysis of randomized bare-metal-stent-controlled trials.
International journal of cardiology 20050408
-
Characterization of the FKBP.rapamycin.FRB ternary complex.
Journal of the American Chemical Society 20050406
-
Treatment of saphenous vein graft lesions with drug-eluting stents: immediate and midterm outcome.
Journal of the American College of Cardiology 20050405
-
Stent underexpansion and residual reference segment stenosis are related to stent thrombosis after sirolimus-eluting stent implantation: an intravascular ultrasound study.
Journal of the American College of Cardiology 20050405
-
The unrestricted use of paclitaxel- versus sirolimus-eluting stents for coronary artery disease in an unselected population: one-year results of the Taxus-Stent Evaluated at Rotterdam Cardiology Hospital (T-SEARCH) registry.
Journal of the American College of Cardiology 20050405
-
Strain-induced vascular endothelial cell proliferation requires PI3K-dependent mTOR-4E-BP1 signal pathway.
American journal of physiology. Heart and circulatory physiology 20050401
-
The impact of the introduction of drug-eluting stents on the clinical practice of surgical and percutaneous treatment of coronary artery disease.
European heart journal 20050401
-
Inhibition of neointima formation by a novel drug-eluting stent system that allows for dose-adjustable, multiple, and on-site stent coating.
Arteriosclerosis, thrombosis, and vascular biology 20050401
-
The Snf1 protein kinase and Sit4 protein phosphatase have opposing functions in regulating TATA-binding protein association with the Saccharomyces cerevisiae INO1 promoter.
Genetics 20050401
-
mTOR-targeted therapy of cancer with rapamycin derivatives.
Annals of oncology : official journal of the European Society for Medical Oncology 20050401
-
Therapeutic drug monitoring for everolimus in kidney transplantation using 12-month exposure, efficacy, and safety data.
Clinical transplantation 20050401
-
The effect of sirolimus on sex hormone levels of male renal transplant recipients.
Clinical transplantation 20050401
-
Rapamycin in patients with chronic renal allograft dysfunction.
Clinical transplantation 20050401
-
Gastrointestinal hemorrhage due to complicated gastroduodenal ulcer disease in liver transplant patients taking sirolimus.
Clinical transplantation 20050401
-
Cytomegalovirus prophylaxis with valganciclovir in African-American renal allograft recipients based on donor/recipient serostatus.
Clinical transplantation 20050401
-
Selectin blockade plus therapy with low-dose sirolimus and cyclosporin a prevent brain death-induced renal allograft dysfunction.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050401
-
Assessing analytical specificity in quantitative analysis using tandem mass spectrometry.
Clinical biochemistry 20050401
-
One year cost effectiveness of sirolimus eluting stents compared with bare metal stents in the treatment of single native de novo coronary lesions: an analysis from the RAVEL trial.
Heart (British Cardiac Society) 20050401
-
Unusual post-transplantation recurrence of focal segmental glomerulosclerosis which resolved with cyclosporine but not with sirolimus.
Transplant international : official journal of the European Society for Organ Transplantation 20050401
-
Certican (Everolimus) in heart transplantation: from clinical trial to clinical experience. Proceedings of a meeting, Vienna, Austria, September 9, 2004.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401
-
From clinical trials to clinical practice: an overview of Certican (everolimus) in heart transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401
-
Prevention of cardiac allograft vasculopathy with Certican (everolimus): the Stanford University experience within the Certican Phase III clinical trial.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401
-
Recommendations for use of Certican (everolimus) after heart transplantation: results from a German and Austrian Consensus Conference.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401
-
Clinical experience with Certican (everolimus) in de novo heart transplant patients at the Deutsches Herzzentrum Berlin.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401
-
Clinical experience with Certican (everolimus) in maintenance heart transplant patients at the Medical University of Vienna.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401
-
Use of sirolimus and low-dose calcineurin inhibitor in lung transplant recipients with renal impairment: results of a controlled pilot study.
Kidney international 20050401
-
Rapid response to rituximab in a pediatric liver transplant recipient with post-transplant lymphoproliferative disease and maintenance with sirolimus monotherapy.
Pediatric transplantation 20050401
-
Efficacy and safety of oral sirolimus to inhibit in-stent intimal hyperplasia.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050401
-
Another attempt to deal with restenosis.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050401
-
Drug eluting stents: case study in the acceptance of a new medical technology.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050401
-
Results and follow-up after implantation of four or more sirolimus-eluting stents in the same patient.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050401
-
Reversal of diabetes in pancreatectomized pigs after transplantation of neonatal porcine islets.
Diabetes 20050401
-
Effective use of liquid chromatography-mass spectrometry (LC/MS) in the routine clinical laboratory for monitoring sirolimus, tacrolimus, and cyclosporine.
Therapeutic drug monitoring 20050401
-
Validation of a practical liquid chomatography with ultraviolet detection method for quantification of whole-blood everolimus in a clinical TDM laboratory.
Therapeutic drug monitoring 20050401
-
Successful use in lung transplantation of an immunosuppressive regimen aimed at reducing target blood levels of sirolimus and tacrolimus.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401
-
Kidney transplantation under minimal immunosuppression after pretransplant lymphoid depletion with Thymoglobulin or Campath.
Journal of the American College of Surgeons 20050401
-
Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors.
Cancer research 20050401
-
Effects of the mammalian target of rapamycin inhibitor CCI-779 used alone or with chemotherapy on human prostate cancer cells and xenografts.
Cancer research 20050401
-
Treatment of psoriasis with topical sirolimus: preclinical development and a randomized, double-blind trial.
The British journal of dermatology 20050401
-
[Islet cell transplantation].
Nihon rinsho. Japanese journal of clinical medicine 20050401
-
Sirolimus improves renal function in cardiac transplantation.
Transplantation proceedings 20050401
-
Graft function, cardiovascular risk factors, and sex hormones in renal transplant recipients on an immunosuppressive regimen of everolimus, reduced dose of cyclosporine, and basiliximab.
Transplantation proceedings 20050401
-
[Research progress of the drug-coated stents].
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20050401
-
Right atrial thrombosis in a heart transplant recipient after initiation of sirolimus.
Acta cardiologica 20050401
-
Drug-eluting stents. The third revolution in percutaneous coronary intervention.
Italian heart journal : official journal of the Italian Federation of Cardiology 20050401
-
mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma.
Neoplasia (New York, N.Y.) 20050401
-
Macrophages rapidly transfer pathogens from lipid raft vacuoles to autophagosomes.
Autophagy 20050401
-
Sirolimus for Kaposi's sarcoma in renal-transplant recipients.
The New England journal of medicine 20050331
-
Immunosuppressive drugs and the risk of cancer after organ transplantation.
The New England journal of medicine 20050331
-
Effect of GLP-1 on glucose transport and its cell signalling in human myocytes.
Regulatory peptides 20050330
-
Design of an intein that can be inhibited with a small molecule ligand.
Journal of the American Chemical Society 20050330
-
Sirolimus-eluting stents to abolish intimal hyperplasia and improve flow in porcine arteriovenous grafts: a 4-week follow-up study.
Circulation 20050329
-
Drug interaction between itraconazole and sirolimus in a primary renal allograft recipient.
Transplantation 20050327
-
Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced by rapamycin through a p38 MAPK- and ERK-dependent pathway.
The Journal of biological chemistry 20050325
-
Characterization of a conserved C-terminal motif (RSPRR) in ribosomal protein S6 kinase 1 required for its mammalian target of rapamycin-dependent regulation.
The Journal of biological chemistry 20050325
-
The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation.
Cell 20050325
-
Short- and long-term clinical outcome after drug-eluting stent implantation for the percutaneous treatment of left main coronary artery disease: insights from the Rapamycin-Eluting and Taxus Stent Evaluated At Rotterdam Cardiology Hospital registries (RESEARCH and T-SEARCH).
Circulation 20050322
-
[Study of the effects of immunosuppressive agents on human islet cells in vitro].
Zhonghua yi xue za zhi 20050316
-
Antileukemic activity of rapamycin in acute myeloid leukemia.
Blood 20050315
-
Comparison of C-reactive protein levels after coronary stenting with bare metal versus sirolimus-eluting stents.
The American journal of cardiology 20050315
-
In-hospital and nine-month outcome of treatment of coronary bifurcational lesions with sirolimus-eluting stent.
The American journal of cardiology 20050315
-
Thirty-day incidence and six-month clinical outcome of thrombotic stent occlusion after bare-metal, sirolimus, or paclitaxel stent implantation.
Journal of the American College of Cardiology 20050315
-
Drug-eluting stent thrombosis: results from a pooled analysis including 10 randomized studies.
Journal of the American College of Cardiology 20050315
-
Rapamycin inhibits ezrin-mediated metastatic behavior in a murine model of osteosarcoma.
Cancer research 20050315
-
A selective small molecule c-MET Inhibitor, PHA665752, cooperates with rapamycin.
Clinical cancer research : an official journal of the American Association for Cancer Research 20050315
-
[Successful treatment of a severe case of idiopathic pulmonary fibrosis with rapamycin].
Medizinische Klinik (Munich, Germany : 1983) 20050315
-
Sirolimus inhibits growth of human hepatoma cells alone or combined with tacrolimus, while tacrolimus promotes cell growth.
World journal of gastroenterology 20050314
-
Clinical and angiographic follow-up study of sirolimus-eluting stent for treatment of in-stent restenosis.
Chinese medical journal 20050305
-
Resistance exercise increases muscle protein synthesis and translation of eukaryotic initiation factor 2Bepsilon mRNA in a mammalian target of rapamycin-dependent manner.
The Journal of biological chemistry 20050304
-
Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes.
Endocrinology 20050301
-
Efficacy of a rapamycin analog (CCI-779) and IFN-gamma in tuberous sclerosis mouse models.
Genes, chromosomes & cancer 20050301
-
HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050301
-
Mouse embryonic stem cells and preimplantation embryos require signaling through the phosphatidylinositol 3-kinase pathway to suppress apoptosis.
Molecular reproduction and development 20050301
-
Small molecule control of pre-mRNA splicing.
RNA (New York, N.Y.) 20050301
-
Everolimus and basiliximab permit suppression by human CD4+CD25+ cells in vitro.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050301
-
Consequences of genetic polymorphisms for sirolimus requirements after renal transplant in patients on primary sirolimus therapy.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050301
-
Constitutive activation of phosphatidyl-inositide 3 kinase contributes to the survival of Hodgkin's lymphoma cells through a mechanism involving Akt kinase and mTOR.
The Journal of pathology 20050301
-
Mechanism of zinc-induced phosphorylation of p70 S6 kinase and glycogen synthase kinase 3beta in SH-SY5Y neuroblastoma cells.
Journal of neurochemistry 20050301
-
Immunosuppression in liver transplantation: beyond calcineurin inhibitors.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20050301
-
Meta-analysis comparing drug-eluting stents with bare metal stents.
The American journal of cardiology 20050301
-
Maintenance of long-term clinical benefit with sirolimus-eluting coronary stents: three-year results of the RAVEL trial.
Circulation 20050301
-
Activity of sirolimus in patients with myelodysplastic syndrome--results of a pilot study.
British journal of haematology 20050301
-
Clinical application of sirolimus in renal transplantation: an update.
Transplant international : official journal of the European Society for Organ Transplantation 20050301
-
Sirolimus quantification by high-performance liquid chromatography with ultraviolet detection.
Transplant international : official journal of the European Society for Organ Transplantation 20050301
-
Efficacy of rapamycin in patient with juvenile rheumatoid arthritis.
Transplant international : official journal of the European Society for Organ Transplantation 20050301
-
Firefly luciferase enzyme fragment complementation for imaging in cells and living animals.
Analytical chemistry 20050301
-
Novel site-specific systemic delivery of Rapamycin with perfluorobutane gas microbubble carrier reduced neointimal formation in a porcine coronary restenosis model.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050301
-
Late follow-up from RAVEL: transition from intention to observation.
Circulation 20050301
-
Sirolimus-eluting stent treatment for isolated proximal left anterior descending artery stenoses. Results from the prospective multi-center German Cypher Registry.
Zeitschrift fur Kardiologie 20050301
-
Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity.
Cancer research 20050301
-
Sirolimus-eluting stents versus the superficial femoral artery: second round.
Journal of vascular and interventional radiology : JVIR 20050301
-
Sirolimus-eluting versus bare nitinol stent for obstructive superficial femoral artery disease: the SIROCCO II trial.
Journal of vascular and interventional radiology : JVIR 20050301
-
[Treatment of lesions with a high risk of stenosis. Comparative study in 300 patients of rapamycin- and Paclitaxel-eluting polymer-based stents, and bare metal stents].
Revista espanola de cardiologia 20050301
-
Rapamycin and UCN-01 synergistically induce apoptosis in human leukemia cells through a process that is regulated by the Raf-1/MEK/ERK, Akt, and JNK signal transduction pathways.
Molecular cancer therapeutics 20050301
-
Restenosis and drug-eluting stents.
The Mount Sinai journal of medicine, New York 20050301
-
LY294002 and rapamycin co-operate to inhibit T-cell proliferation.
British journal of pharmacology 20050301
-
Effect of multiple-dose erythromycin on everolimus pharmacokinetics.
European journal of clinical pharmacology 20050301
-
A combination of anergic cells' adoptive transfer and rapamycin therapy prolongs cardiac allograft survival in mice.
Scandinavian journal of immunology 20050301
-
Signal transduction pathways in androgen-dependent and -independent prostate cancer cell proliferation.
Endocrine-related cancer 20050301
-
Sirolimus: a new option in transplantation.
Expert opinion on pharmacotherapy 20050301
-
Recurrence of migraine with aura due to tacrolimus therapy in a liver transplant recipient successfully treated with sirolimus substitution.
Headache 20050301
-
Sirolimus in pediatric renal transplantation.
Transplantation proceedings 20050301
-
Sirolimus-based therapy with or without cyclosporine: long-term follow-up in renal transplant patients.
Transplantation proceedings 20050301
-
A randomized trial of steroid avoidance in renal transplant patients treated with everolimus and cyclosporine.
Transplantation proceedings 20050301
-
Corticosteroid avoidance ameliorates lymphocele formation and wound healing complications associated with sirolimus therapy.
Transplantation proceedings 20050301
-
Rabbit antithymocyte globulin: a postoperative risk factor for sirolimus-treated renal transplant patients?
Transplantation proceedings 20050301
-
Addition of sirolimus to cyclosporine in long-term kidney transplant recipients to withdraw steroid.
Transplantation proceedings 20050301
-
The effect of rapamycin on the healing of the ureteric anastomosis and wound healing.
Transplantation proceedings 20050301
-
Effect of rapamycin on the healing of the bile duct.
Transplantation proceedings 20050301
-
Severe limb lymphedema in sirolimus-treated patients.
Transplantation proceedings 20050301
-
Cyclosporine and rapamycin act in a synergistic and dose-dependent manner in a model of immunosuppressant-induced kidney damage.
Transplantation proceedings 20050301
-
Sirolimus delays recovery from posttransplant renal failure in kidney graft recipients.
Transplantation proceedings 20050301
-
Pharmacokinetics of mycophenolic acid in kidney transplant patients receiving sirolimus versus cyclosporine.
Transplantation proceedings 20050301
-
No-load sirolimus with tacrolimus and steroids is safe and effective in renal transplantation.
Transplantation proceedings 20050301
-
Regression of Kaposi's sarcoma in renal graft recipients after conversion to sirolimus treatment.
Transplantation proceedings 20050301
-
Graft survival and immune regulation of pancreas allograft recipients induced with thymoglobulin, sirolimus, and cyclosporine.
Transplantation proceedings 20050301
-
Impact of a sirolimus/tacrolimus-based immunosuppressive regimen on kidney function after islet transplantation.
Transplantation proceedings 20050301
-
Evidence for down-regulation of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways in Ames dwarf mice.
The journals of gerontology. Series A, Biological sciences and medical sciences 20050301
-
Primary stenting of occluded native coronary arteries II--rationale and design of the PRISON II study: a randomized comparison of bare metal stent implantation with sirolimus-eluting stent implantation for the treatment of chronic total coronary occlusions.
American heart journal 20050301
-
Cutaneous adverse events in renal transplant recipients receiving sirolimus-based therapy.
Transplantation 20050227
-
High-performance liquid chromatography with ultraviolet detection for therapeutic drug monitoring of everolimus.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225
-
Potent inhibitory effect of sirolimus on circulating vascular progenitor cells.
Circulation 20050222
-
[Recent progress and problems in percutaneous coronary intervention].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20050220
-
Specific interactions of PP2A and PP2A-like phosphatases with the yeast PTPA homologues, Ypa1 and Ypa2.
The Biochemical journal 20050215
-
Activation of the p70 S6 kinase by all-trans-retinoic acid in acute promyelocytic leukemia cells.
Blood 20050215
-
Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer.
Blood 20050215
-
Intravascular ultrasound assessment of lesions with target vessel failure after sirolimus-eluting stent implantation.
The American journal of cardiology 20050215
-
Early and mid-term results of drug-eluting stent implantation in unprotected left main.
Circulation 20050215
-
Maintenance immunosuppression use and the associated risk of avascular necrosis after kidney transplantation in the United States.
Transplantation 20050215
-
Drug-eluting stents for diabetes mellitus: a rush to judgment?
Journal of the American College of Cardiology 20050215
-
Exceptional circumstances and heart transplantation.
The New Zealand medical journal 20050211
-
REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase.
Oncogene 20050210
-
[New generation of percutaneous coronary intervention: drug-eluting stent].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20050210
-
Scientists hopeful as they uncover molecular clues to prostate cancer.
Journal of the National Cancer Institute 20050202
-
EGF receptor transactivation mediates ANG II-stimulated mitogenesis in intestinal epithelial cells through the PI3-kinase/Akt/mTOR/p70S6K1 signaling pathway.
American journal of physiology. Gastrointestinal and liver physiology 20050201
-
Prevention of lethal acute GVHD with an agonistic CD28 antibody and rapamycin.
Blood 20050201
-
Regulation of leucine uptake by tor1+ in Schizosaccharomyces pombe is sensitive to rapamycin.
Genetics 20050201
-
Rapamycin attenuates vascular wall inflammation and progenitor cell promoters after angioplasty.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050201
-
Application of commercial calibrators for the analysis of immunosuppressant drugs in whole blood.
Clinical chemistry 20050201
-
Complete assignments of the 1H and 13C resonances of 40-epi-(N1-tetrazolyl)-rapamycin and revised 13C assignments for rapamycin.
Magnetic resonance in chemistry : MRC 20050201
-
Effects of maternal starvation on hepatocyte proliferation in the late gestation fetal rat.
Pediatric research 20050201
-
Rapamycin-treated, alloantigen-pulsed host dendritic cells induce ag-specific T cell regulation and prolong graft survival.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050201
-
Inhibition of endogenous SHIP2 ameliorates insulin resistance caused by chronic insulin treatment in 3T3-L1 adipocytes.
Diabetologia 20050201
-
Large coronary artery aneurysms following sirolimus eluting stent implantation.
Heart (British Cardiac Society) 20050201
-
Economic evaluation of everolimus vs. azathioprine at one year after de novo heart transplantation.
Clinical transplantation 20050201
-
An open-label, pilot study evaluating the safety and efficacy of converting from calcineurin inhibitors to sirolimus in established renal allograft recipients with moderate renal insufficiency.
Clinical transplantation 20050201
-
Improved renal function in de novo renal transplant patients on sirolimus maintenance therapy following discontinuation of cyclosporine.
Therapeutic drug monitoring 20050201
-
The portal immunosuppressive storm: relevance to islet transplantation?
Therapeutic drug monitoring 20050201
-
Gastrointestinal leukocytoclastic vasculitis: an adverse effect of sirolimus.
Pediatric transplantation 20050201
-
Inhibitory effect of rapamycin on corneal neovascularization in vitro and in vivo.
Investigative ophthalmology & visual science 20050201
-
Indefinite survival of neonatal porcine islet xenografts by simultaneous targeting of LFA-1 and CD154 or CD45RB.
Diabetes 20050201
-
Cypher drug-eluting stent treatment of tibioperoneal obstructive disease: a case report.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050201
-
Beware the sirens' call.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050201
-
Is overdilatation of 3.0 mm sirolimus-eluting stent associated with a higher restenosis rate?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050201
-
Sirolimus-eluting stent implantation for unprotected left main coronary artery stenosis: comparison with bare metal stent implantation.
Journal of the American College of Cardiology 20050201
-
Percutaneous coronary intervention and drug-eluting stents.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050201
-
Economic evaluation of sirolimus-eluting stents.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050201
-
The dollars and sense of drug-eluting stents.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050201
-
Use of everolimus-eluting stent with a bioresorbable polymer coating for treatment of recurrent in-stent restenosis.
The Journal of invasive cardiology 20050201
-
Rotational ablation of an unexpandable sirolimus-eluting stent.
The Journal of invasive cardiology 20050201
-
Rapamycin rescue therapy in patients after kidney transplantation: first clinical experience.
Transplant international : official journal of the European Society for Organ Transplantation 20050201
-
Rapamycin treatment is associated with an increased apoptosis rate in experimental vein grafts.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20050201
-
Rapamycin (sirolimus) as a steroid-sparing agent in dermatomyositis.
Journal of the American Academy of Dermatology 20050201
-
Sirolimus immunosuppression in pediatric heart transplant recipients: a single-center experience.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050201
-
How drug-eluting stents keep coronary blood flowing.
Nursing 20050201
-
Transcriptional profiles in peripheral blood mononuclear cells prognostic of clinical outcomes in patients with advanced renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 20050201
-
Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members.
Molecular cancer therapeutics 20050201
-
Assessment of glomerular and tubular functions in renal transplant patients receiving cyclosporine A in combination with either sirolimus or everolimus.
Clinical nephrology 20050201
-
PKB/Akt mediates radiosensitization by the signaling inhibitor LY294002 in human malignant gliomas.
Journal of neuro-oncology 20050201
-
Stent competition helps prices.
Hospital material[dollar sign] management 20050201
-
Patent infringement.
Nature reviews. Drug discovery 20050201
-
Long-term inducible gene expression in the eye via adeno-associated virus gene transfer in nonhuman primates.
Human gene therapy 20050201
-
Effects of rapamycin on the epithelial-to-mesenchymal transition of human peritoneal mesothelial cells.
The International journal of artificial organs 20050201
-
Sirolimus-eluting stent implantation for chronic total occlusion of the left main coronary artery.
Journal of interventional cardiology 20050201
-
Coronary restenosis after implantation of drug-eluting stents.
Minerva cardioangiologica 20050201
-
Can oral sirolimus therapy prevent in-stent restenosis?
Nature clinical practice. Cardiovascular medicine 20050201
-
Sirolimus and ACE-inhibitors: a note of caution.
Transplantation 20050127
-
Relationship of late loss in lumen diameter to coronary restenosis in sirolimus-eluting stents.
Circulation 20050125
-
Alternative phospholipase D/mTOR survival signal in human breast cancer cells.
Oncogene 20050120
-
A prospective randomized comparison between paclitaxel and sirolimus stents in the real world of interventional cardiology: the TAXi trial.
Journal of the American College of Cardiology 20050118
-
Altered trafficking of CD8+ memory T cells after implantation of rapamycin-eluting stents in patients with coronary artery disease.
Immunology letters 20050115
-
Impact of sirolimus-eluting stent on the outcome of patients with chronic total occlusions.
The American journal of cardiology 20050115
-
Impact of baseline renal function on mortality after percutaneous coronary intervention with sirolimus-eluting stents or bare metal stents.
The American journal of cardiology 20050115
-
Interleukin-12-induced interferon-gamma production by human peripheral blood T cells is regulated by mammalian target of rapamycin (mTOR).
The Journal of biological chemistry 20050114
-
Sirolimus-eluting stent or paclitaxel-eluting stent vs balloon angioplasty for prevention of recurrences in patients with coronary in-stent restenosis: a randomized controlled trial.
JAMA 20050112
-
[Nephrology].
Revue medicale suisse 20050105
-
Direct stenting of native de novo coronary artery lesions with the sirolimus-eluting stent: a post hoc subanalysis of the pooled E- and C-SIRIUS trials.
Journal of the American College of Cardiology 20050104
-
Effects of rapamycin on cardiac and skeletal muscle contraction and crossbridge cycling.
The Journal of pharmacology and experimental therapeutics 20050101
-
Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts.
Molecular endocrinology (Baltimore, Md.) 20050101
-
An intramolecular ionic hydrogen bond stabilizes a cis amide bond rotamer of a ring-opened rapamycin-degradation product.
Magnetic resonance in chemistry : MRC 20050101
-
Effects of rapamycin in the Eker rat model of tuberous sclerosis complex.
Pediatric research 20050101
-
Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease.
Journal of the American Society of Nephrology : JASN 20050101
-
Monitoring of immunosuppressive therapy in renal transplanted patients.
Contributions to nephrology 20050101
-
Decreased Cytomegalovirus infection after antilymphocyte therapy in sirolimus-treated renal transplant patients.
International immunopharmacology 20050101
-
Nonnephrotoxic immunosuppression in patients after liver transplantation.
International immunopharmacology 20050101
-
Center experience in liver transplantation (LTX): management of dermal side effects caused by sirolimus.
International immunopharmacology 20050101
-
Immunosuppressant drug monitoring: is the laboratory meeting clinical expectations?
The Annals of pharmacotherapy 20050101
-
A meta-analysis of clinical trials of paclitaxel- and sirolimus-eluting stents in patients with obstructive coronary artery disease.
British journal of clinical pharmacology 20050101
-
Immunosuppression: towards a logical approach in liver transplantation.
Clinical and experimental immunology 20050101
-
CD28 regulates the translation of Bcl-xL via the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway.
Journal of immunology (Baltimore, Md. : 1950) 20050101
-
Strategies for minimizing immunosuppression in kidney transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20050101
-
Early cyclosporine withdrawal from a sirolimus-based regimen results in better renal allograft survival and renal function at 48 months after transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20050101
-
Dosing of rapamycin is critical to achieve an optimal antiangiogenic effect against cancer.
Transplant international : official journal of the European Society for Organ Transplantation 20050101
-
Cardiovascular risk profile in patients treated with sirolimus after renal transplantation.
Kidney international. Supplement 20050101
-
Sirolimus- and paclitaxel-eluting stents in comparison with balloon angioplasty for treatment of in-stent restenosis.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050101
-
Angiographic results of the first human experience with everolimus-eluting stents for the treatment of coronary lesions (the FUTURE I trial).
The American journal of cardiology 20050101
-
Mammalian target of rapamycin (mTOR) inhibition in chronic lymphocytic B-cell leukemia: a new therapeutic option.
Leukemia & lymphoma 20050101
-
A novel technique for on-capillary preconcentration of anionic compounds applied to the trace analysis of rapamycin in human blood by capillary electrophoresis.
Electrophoresis 20050101
-
Rapamycin (sirolimus) for treatment of chronic graft-versus-host disease.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050101
-
Stent implantation activates RhoA in human arteries: inhibitory effect of rapamycin.
Journal of vascular research 20050101
-
Nephrotoxicity of rapamycin: an emerging problem in clinical medicine.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050101
-
De novo thrombotic microangiopathy following treatment with sirolimus: report of two cases.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050101
-
Immunophilin ligands FK506 and cyclosporine A improve neurologic and histopathologic outcome after transient spinal cord ischemia in rabbits.
The Journal of thoracic and cardiovascular surgery 20050101
-
A multicenter pilot study of early (4-day) steroid cessation in renal transplant recipients under simulect, tacrolimus and sirolimus.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050101
-
Sirolimus impairs improvement of the gonadal function after renal transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050101
-
Population pharmacokinetics of CCI-779: correlations to safety and pharmacogenomic responses in patients with advanced renal cancer.
Clinical pharmacology and therapeutics 20050101
-
Sirolimus-eluting stents for the treatment of atherosclerotic ostial lesions.
The Journal of invasive cardiology 20050101
-
Sirolimus-eluting stents for the treatment of atherosclerotic ostial lesions.
The Journal of invasive cardiology 20050101
-
Determining sensitivity to rapamycin and its analogues in breast cancer patients.
Breast cancer research : BCR 20050101
-
Tor and cyclic AMP-protein kinase A: two parallel pathways regulating expression of genes required for cell growth.
Eukaryotic cell 20050101
-
The Coronary Artery Revascularisation in Diabetes (CARDia) trial: background, aims, and design.
American heart journal 20050101
-
Effects of conversion from sirolimus oral solution to tablets in stable Taiwanese renal transplant recipients.
Journal of the Formosan Medical Association = Taiwan yi zhi 20050101
-
Choosing a drug-eluting stent: a comparison between CYPHER and TAXUS.
Reviews in cardiovascular medicine 20050101
-
Safety and efficacy of drug-eluting stents.
Reviews in cardiovascular medicine 20050101
-
Coping with rejection: immunosuppressants and organ transplantation.
Drug discovery today 20050101
-
Benefit-risk assessment of sirolimus in renal transplantation.
Drug safety 20050101
-
Sphingosine-1-phosphate-induced smooth muscle cell migration involves the mammalian target of rapamycin.
Journal of vascular surgery 20050101
-
Mechanisms of action of rapamycin in gliomas.
Neuro-oncology 20050101
-
Cardiovascular device development: drug-eluting stents and implantable devices for the treatment of heart failure--the view from the Circulatory System Advisory Panel.
American journal of therapeutics 20050101
-
[New immunodepressant drugs for the prevention and control of kidney transplant rejection].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20050101
-
Protein synthesis-dependent LTP in isolated dendrites of CA1 pyramidal cells.
Hippocampus 20050101
-
Prograf produces a molecular environment favoring antifibrosis, an effect reversed by the addition of rapamune.
Transplantation proceedings 20050101
-
Immunological evaluation of combination therapy with tacrolimus and sirolimus on long-term allograft survival in nonhuman primates.
Transplantation proceedings 20050101
-
Predominant inhibition of interleukin-6 synthesis in patient-specific endothelial cells by mTOR inhibitors below a concentration range where cell proliferation is affected and mitotic arrest takes place.
Transplantation proceedings 20050101
-
Sirolimus-mediated prolongation of rat cardiac allograft survival is enhanced by beta1 integrin very late antigen-4 blockade.
Transplantation proceedings 20050101
-
Mycophenolate mofetil inhibits intimal hyperplasia and attenuates the expression of genes favouring smooth muscle cell proliferation and migration.
Transplantation proceedings 20050101
-
A microparticle enzyme immunoassay to measure sirolimus.
Transplantation proceedings 20050101
-
Involvement of mitogen-stimulated p70-S6 kinase in the development of sensitization to the methamphetamine-induced rewarding effect in rats.
Neuroscience 20050101
-
Medium-term results from the clinical and angiographic follow-up of patients after angioplasty and implantation of sirolimus-eluting stents.
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20050101
-
The use of drug-eluting stents in everyday clinical practice: can the results of randomised trials be achieved in the 'real world'?
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20050101
-
Inhibition of different intracellular signal cascades in human pancreatic cancer cells.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20050101
-
Inhibition of mTOR suppresses experimental liver tumours.
Anticancer research 20050101
-
[The first experience with sirolimus (Rapamune) after kidney transplantation in Lithuania].
Medicina (Kaunas, Lithuania) 20050101
-
Sirolimus-eluting stents for treatment of in-stent restenosis: immediate and late results.
Texas Heart Institute journal 20050101
-
Sirolimus increases tissue factor expression but not activity in cultured human vascular smooth muscle cells.
BMC cardiovascular disorders 20050101
-
Percutaneous therapy of bifurcation lesions with drug-eluting stent implantation: the Culotte technique revisited.
International journal of cardiovascular interventions 20050101
-
Therapeutic targeting of multiple signaling pathways in malignant pleural mesothelioma.
Oncology 20050101
-
Sirolimus: the evidence for clinical pharmacokinetic monitoring.
Clinical pharmacokinetics 20050101
-
Overcoming cisplatin resistance by mTOR inhibitor in lung cancer.
Molecular cancer 20050101
-
Impaired glomerular and tubular function as a short-term effect of sirolimus treatment in the rat.
American journal of nephrology 20050101
-
Lack of effect of rapamycin in anti-CCP antibody production in a rheumatoid arthritis kidney allograft recipient.
Clinical and experimental rheumatology 20050101
-
Direct stenting with sirolimus-eluting stents.
The American heart hospital journal 20050101
-
Treatment of double vessel coronary artery disease by totally endoscopic bypass surgery and drug-eluting stent placement in one simultaneous hybrid session.
The heart surgery forum 20050101
-
Impressive regression of primary liver cancer after treatment with sirolimus.
Acta oncologica (Stockholm, Sweden) 20050101
-
[Acute, idiopathic, bilateral uveitis with periphlebitis--case report].
Klinika oczna 20050101
-
Sirolimus- versus paclitaxel-eluting stent implantation for unprotected left main coronary artery stenosis.
Cardiology 20050101
-
Treating breast cancer through novel inhibitors of the phosphatidylinositol 3'-kinase pathway.
Breast cancer research : BCR 20050101
-
Calcineurin inhibitor-free immunosuppression in renal transplantation.
Transplantation proceedings 20050101
-
Conversion to sirolimus in a population of kidney and kidney-pancreas transplant recipients.
Transplantation proceedings 20050101
-
Combined use of tacrolimus and sirolimus in de novo renal transplant patients: current data.
Transplantation proceedings 20050101
-
Is sirolimus responsible for proteinuria?
Transplantation proceedings 20050101
-
Sirolimus-associated acute respiratory distress syndrome in a renal transplant recipient.
Transplantation proceedings 20050101
-
Evaluation of a new immunoassay to measure sirolimus blood concentrations compared to a tandem mass-spectrometric chromatographic analysis.
Transplantation proceedings 20050101
-
Determination of rapamycin: quantification of the sodiated species by an ion trap mass spectrometer as an alternative to the ammoniated complex analysis by triple quadrupole.
Rapid communications in mass spectrometry : RCM 20050101
-
The mammalian target of the rapamycin (mTOR) kinase pathway: its role in tumourigenesis and targeted antitumour therapy.
Cellular & molecular biology letters 20050101
-
[Evidences in immunosuppression in the maintenance of renal transplantation].
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20050101
-
Acute and intermediate-term procedural results using cypher stenting to treat multi-vessel coronary artery disease.
International journal of cardiovascular interventions 20050101
-
Drug-eluting stents for the treatment of in-stent restenosis: a clinical review.
Cardiovascular revascularization medicine : including molecular interventions 20050101
-
Segmental vessel wall shear stress and neointimal formation after sirolimus-eluting stent implantation: physiological insights in a porcine coronary model.
Cardiovascular revascularization medicine : including molecular interventions 20050101
-
Sirolimus-induced acneiform eruption.
Dermatology (Basel, Switzerland) 20050101
-
Drug-eluting stents: immediate and long-term results.
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20050101
-
What is the best contemporary treatment for in-stent restenosis?
Cardiovascular revascularization medicine : including molecular interventions 20050101
-
Drug-eluting stents for the treatment of in-stent restenosis--'real world' double centre experience in consecutive patients.
International journal of cardiovascular interventions 20050101
-
Successful use of sirolimus-eluting stents for treatment of ST-elevation acute myocardial infarction caused by left main coronary artery occlusion.
Texas Heart Institute journal 20050101
-
Long-term outcome after coronary angioplasty: where do we stand?
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20050101
-
Effects of combined treatment with rapamycin and cotylenin A, a novel differentiation-inducing agent, on human breast carcinoma MCF-7 cells and xenografts.
Breast cancer research : BCR 20050101
-
A case of giant aneurysm following percutaneous coronary intervention.
Indian heart journal 20050101
-
[Immunosuppression for kidney transplant recipients: current strategies].
Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20050101
-
Rapamycin inhibits platelet-derived growth factor-induced collagen, but not fibronectin, synthesis in rat mesangial cells.
Yonsei medical journal 20041231
-
A pilot study of calcineurin inhibitors (CNIs) and steroid avoidance immunosuppressive protocol among living donor kidney transplant recipients.
Yonsei medical journal 20041231
-
TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1.
Cell 20041229
-
Glucose-stimulated protein synthesis in pancreatic beta-cells parallels an increase in the availability of the translational ternary complex (eIF2-GTP.Met-tRNAi) and the dephosphorylation of eIF2 alpha.
The Journal of biological chemistry 20041224
-
The serine/threonine kinase Akt Promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase.
The Journal of biological chemistry 20041224
-
Growth-regulated recruitment of the essential yeast ribosomal protein gene activator Ifh1.
Nature 20041223
-
[Drug-eluting stents in coronary arteries. The risk of restenosis is drastically reduced].
Lakartidningen 20041223
-
Systemic rapamycin inhibits retinal and choroidal neovascularization in mice.
Molecular vision 20041222
-
Quantitative assessment of angiographic restenosis after sirolimus-eluting stent implantation in native coronary arteries.
Circulation 20041221
-
Drug therapy in the heart transplant recipient: part II: immunosuppressive drugs.
Circulation 20041221
-
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages.
Cell 20041217
-
In vivo antitumor effects of the mTOR inhibitor CCI-779 against human multiple myeloma cells in a xenograft model.
Blood 20041215
-
Combination of the mTOR inhibitor rapamycin and CC-5013 has synergistic activity in multiple myeloma.
Blood 20041215
-
Identification of filamin C as a new physiological substrate of PKBalpha using KESTREL.
The Biochemical journal 20041215
-
Intravascular ultrasonic comparative analysis of degree of intimal hyperplasia produced by four different stents in the coronary arteries.
The American journal of cardiology 20041215
-
mTOR and P70 S6 kinase expression in primary liver neoplasms.
Clinical cancer research : an official journal of the American Association for Cancer Research 20041215
-
Conjugation of an antibody to cross-linked fibrin for targeted delivery of anti-restenotic drugs.
Journal of controlled release : official journal of the Controlled Release Society 20041210
-
Sirolimus-eluting vs uncoated stents for prevention of restenosis in small coronary arteries: a randomized trial.
JAMA 20041208
-
Stenting small coronary arteries: works in progress.
JAMA 20041208
-
PKC-eta mediates glioblastoma cell proliferation through the Akt and mTOR signaling pathways.
Oncogene 20041202
-
Insulin facilitation of muscle protein synthesis following resistance exercise in hindlimb-suspended rats is independent of a rapamycin-sensitive pathway.
American journal of physiology. Endocrinology and metabolism 20041201
-
Toxin-induced tail phosphorylation of hepatocellular S6 kinase: evidence for a dual involvement of the AMP-activated protein kinase in S6 kinase regulation.
Toxicological sciences : an official journal of the Society of Toxicology 20041201
-
Apelin (65-77) activates p70 S6 kinase and is mitogenic for umbilical endothelial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20041201
-
Dyslipidemia during sirolimus therapy in patients after liver transplantation.
Clinical transplantation 20041201
-
Fate of donor kidney: laparoscopic versus open technique.
The Journal of urology 20041201
-
Which parameter should be chosen as primary endpoint for randomized drug-eluting stent studies?
Journal of interventional cardiology 20041201
-
Clinical experiences using everolimus-eluting stents in patients with coronary artery disease.
Journal of interventional cardiology 20041201
-
New approaches to ostial and bifurcation lesions.
Journal of interventional cardiology 20041201
-
Vascular brachytherapy versus sirolimus eluting stents for the treatment of in-stent restenosis: a prospective registry.
Heart (British Cardiac Society) 20041201
-
Random mutagenesis of an essential Candida albicans gene.
Current genetics 20041201
-
New bifurcation stenting technique: shunt stenting.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20041201
-
Recovery of chronic renal impairment with sirolimus after lung transplantation.
The Annals of thoracic surgery 20041201
-
Rapamycin inhibits doxorubicin-induced NF-kappaB/Rel nuclear activity and enhances the apoptosis of melanoma cells.
European journal of cancer (Oxford, England : 1990) 20041201
-
Sirolimus with neoral versus mycophenolate mofetil with neoral is associated with decreased renal allograft survival.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041201
-
Therapeutic drug monitoring for everolimus in heart transplant recipients based on exposure-effect modeling.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041201
-
Mammalian target of rapamycin (mTOR) inhibitors as anti-cancer agents.
Current cancer drug targets 20041201
-
The complexity of PTEN: mutation, marker and potential target for therapeutic intervention.
Expert opinion on therapeutic targets 20041201
-
Therapeutic potential of target of rapamycin inhibitors.
Expert opinion on therapeutic targets 20041201
-
Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity.
Clinical cancer research : an official journal of the American Association for Cancer Research 20041201
-
Treatment of coronary artery disease in dialysis patients with sirolimus-eluting stents: 1-year clinical follow-up of a consecutive series of cases.
The Journal of invasive cardiology 20041201
-
Sirolimus-eluting stents for percutaneous coronary intervention in acute myocardial infarction Lesson from a case-controlled comparison of bare metal versus drug-eluting stents in thrombus-laden lesions.
Zeitschrift fur Kardiologie 20041201
-
Cap-independent protein translation is initially responsible for 4-(N-methylnitrosamino)-1-(3-pyridyl)-butanone (NNK)-induced apoptosis in normal human bronchial epithelial cells.
Journal of veterinary science 20041201
-
Pharmacokinetics of immunosuppressants: a perspective on ethnic differences.
International journal of clinical pharmacology and therapeutics 20041201
-
[16th EORTC-NCI-AACR symposium on new molecular targets and cancer therapeutics].
Bulletin du cancer 20041201
-
Akt up-regulation increases resistance to microtubule-directed chemotherapeutic agents through mammalian target of rapamycin.
Molecular cancer therapeutics 20041201
-
[Percutaneous coronary angioplasty in diabetic patients: new prospects with drug-eluting stents].
Revue medicale de Liege 20041201
-
Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase.
Molecular and cellular biochemistry 20041201
-
Initial experience with sirolimus and mycophenolate mofetil for renal rescue from cyclosporine nephrotoxicity after heart transplantation.
Transplantation proceedings 20041201
-
The relative proportions of sirolimus metabolites in blood using HPLC with mass-spectrometric detection.
Transplantation proceedings 20041201
-
Clinical relevance of sirolimus drug interactions in transplant patients.
Transplantation proceedings 20041201
-
Sirolimus upregulates aP2 expression in human monocytes and macrophages.
Transplantation proceedings 20041201
-
Absence of teratogenicity of sirolimus used during early pregnancy in a liver transplant recipient.
Transplantation proceedings 20041201
-
What reimbursement for coronary revascularization with drug-eluting stents?
The European journal of health economics : HEPAC : health economics in prevention and care 20041201
-
Exposure-response relationships and drug interactions of sirolimus.
The AAPS journal 20041201
-
Mycobacterium xenopi pulmonary infection in two renal transplant recipients under sirolimus therapy.
Transplant infectious disease : an official journal of the Transplantation Society 20041201
-
Mammalian target of rapamycin.
Seminars in oncology 20041201
-
Mutagenic and cytotoxic effects of immunosuppressive drugs on human lymphocyte cultures.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20041201
-
Nonuniform strut distribution correlates with more neointimal hyperplasia after sirolimus-eluting stent implantation.
Circulation 20041130
-
Everolimus (Certican) 12-month safety and efficacy versus mycophenolate mofetil in de novo renal transplant recipients.
Transplantation 20041127
-
Sirolimus may not cause neurotoxicity in kidney and liver transplant recipients.
Neurology 20041123
-
Memory-like alterations in Aplysia axons after nerve injury or localized depolarization.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20041117
-
Comparison of late luminal loss response pattern after sirolimus-eluting stent implantation or conventional stenting.
Circulation 20041116
-
Comparison of clinical and angiographic outcome of sirolimus-eluting stent implantation versus cutting balloon angioplasty for coronary in-stent restenosis.
The American journal of cardiology 20041115
-
Targeted T-cell depletion or CD154 blockade generates mixed hemopoietic chimerism and donor-specific tolerance in mice treated with sirolimus and donor bone marrow.
Transplantation 20041115
-
Early cyclosporine a withdrawal in kidney-transplant recipients receiving sirolimus prevents progression of chronic pathologic allograft lesions.
Transplantation 20041115
-
Everolimus and reduced-exposure cyclosporine in de novo renal-transplant recipients: a three-year phase II, randomized, multicenter, open-label study.
Transplantation 20041115
-
Investigation of pediatric renal transplant recipients with heavy proteinuria after sirolimus rescue.
Transplantation 20041115
-
Construction of a cyclin D1-Cdk2 fusion protein to model the biological functions of cyclin D1-Cdk2 complexes.
The Journal of biological chemistry 20041112
-
Autocrine transforming growth factor alpha regulates cell adhesion by multiple signaling via specific phosphorylation sites of p70S6 kinase in colon cancer cells.
The Journal of biological chemistry 20041105
-
Tor signaling and nutrient-based signals converge on Mks1p phosphorylation to regulate expression of Rtg1.Rtg3p-dependent target genes.
The Journal of biological chemistry 20041105
-
Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20041103
-
Phase I/pharmacokinetic study of CCI-779 in patients with recurrent malignant glioma on enzyme-inducing antiepileptic drugs.
Investigational new drugs 20041101
-
The mTOR signaling pathway mediates control of ribosomal protein mRNA translation in rat liver.
The international journal of biochemistry & cell biology 20041101
-
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.
Nature cell biology 20041101
-
Cyclooxygenase-2 expression in experimental post-transplant obliterative bronchiolitis.
The Journal of pathology 20041101
-
De novo kidney transplantation without use of calcineurin inhibitors preserves renal structure and function at two years.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041101
-
Predictors of success in conversion from calcineurin inhibitor to sirolimus in chronic allograft dysfunction.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041101
-
Initiation of mRNA translation in oncogenesis: the role of eIF4E.
Cell cycle (Georgetown, Tex.) 20041101
-
Targeting metastatic leiomyosarcoma by rapamycin plus gemcitabine: an intriguing clinical observation.
International journal of molecular medicine 20041101
-
Sirolimus and angiotensin-converting enzyme inhibitors together induce tongue oedema in renal transplant recipients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041101
-
Sirolimus-induced pneumonitis, sinusitis and macular oedema.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041101
-
Sirolimus- or paclitaxel-eluting stents to prevent coronary artery restenosis.
Expert opinion on pharmacotherapy 20041101
-
Vascular restenosis - striving for therapy.
Expert opinion on pharmacotherapy 20041101
-
Drug-eluting stents have made brachytherapy obsolete.
Current opinion in cardiology 20041101
-
Selectin inhibitor bimosiamose prolongs survival of kidney allografts by reduction in intragraft production of cytokines and chemokines.
Journal of the American Society of Nephrology : JASN 20041101
-
regulation of peroxisome proliferator-activated receptor-gamma activity by mammalian target of rapamycin and amino acids in adipogenesis.
Diabetes 20041101
-
Bcl-2 and CCND1/CDK4 expression levels predict the cellular effects of mTOR inhibitors in human ovarian carcinoma.
Apoptosis : an international journal on programmed cell death 20041101
-
Sirolimus-eluting stents for the prevention of restenosis in a worst-case scenario of diffuse and recurrent in-stent restenosis.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20041101
-
Drug-eluting stents for secondary prevention of restenosis.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20041101
-
Hybrid coronary revascularization in the era of drug-eluting stents.
The Annals of thoracic surgery 20041101
-
Rapamycin-eluting stents for the treatment of bifurcated coronary lesions: a randomized comparison of a simple versus complex strategy.
American heart journal 20041101
-
Drug-eluting stents: a mechanical and pharmacologic approach to coronary artery disease.
Pharmacotherapy 20041101
-
Everolimus suppresses cancellous bone loss, bone resorption, and cathepsin K expression by osteoclasts.
Bone 20041101
-
Combining targeted agents in lung cancer.
Clinical lung cancer 20041101
-
[Consensus-recommendations for sirolimus in liver transplantation].
Zeitschrift fur Gastroenterologie 20041101
-
Sirolimus addition is beneficial for renal allograft dysfunction due to simultaneous acute rejection episode and calcineurin inhibitor nephrotoxicity.
Transplantation proceedings 20041101
-
Combined use of sirolimus and voriconazole in renal transplantation: a report of two cases.
Transplantation proceedings 20041101
-
Targeting the molecular target of rapamycin (mTOR).
Current opinion in oncology 20041101
-
Bibliography. Current world literature. Therapeutic modalities.
Current opinion in oncology 20041101
-
Molecular cross-talk between MEK1/2 and mTOR signaling during recovery of 293 cells from hypertonic stress.
The Journal of biological chemistry 20041029
-
Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1alpha, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT signaling.
The Journal of biological chemistry 20041029
-
Immunomodulatory effects of combination of pooled human gammaglobulin and rapamycin on cell proliferation and apoptosis in the mixed lymphocyte reaction.
Transplantation 20041027
-
Sirolimus in de novo heart transplant recipients reduces acute rejection and prevents coronary artery disease at 2 years: a randomized clinical trial.
Circulation 20041026
-
Targeting the mammalian target of rapamycin (mTOR): a new approach to treating cancer.
British journal of cancer 20041018
-
Rapamycin causes activation of protein phosphatase-2A1 and nuclear translocation of PCNA in CD4+ T cells.
Biochemical and biophysical research communications 20041015
-
Rapamycin inhibits proliferation and differentiation of human endothelial progenitor cells in vitro.
Experimental cell research 20041015
-
Bivalirudin versus heparin as an antithrombotic agent in patients treated with a sirolimus-eluting stent.
The American journal of cardiology 20041015
-
BK virus-associated nephropathy in renal allograft recipients: rescue therapy by sirolimus-based immunosuppression.
Transplantation 20041015
-
Putting the rap on Akt.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041015
-
Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 20041015
-
Effect of rapamycin alone and in combination with antiangiogenesis therapy in an orthotopic model of human pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 20041015
-
Targeting mammalian target of rapamycin synergistically enhances chemotherapy-induced cytotoxicity in breast cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 20041015
-
Problems with drug-eluting coronary stents--the FDA perspective.
The New England journal of medicine 20041014
-
Receptor activity-independent recruitment of betaarrestin2 reveals specific signalling modes.
The EMBO journal 20041013
-
In rat hepatocytes glucagon increases mammalian target of rapamycin phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream targets induced by insulin and amino acids.
The Journal of biological chemistry 20041008
-
Oral rapamycin to inhibit restenosis after stenting of de novo coronary lesions: the Oral Rapamune to Inhibit Restenosis (ORBIT) study.
Journal of the American College of Cardiology 20041006
-
Evaluation of a cyano stationary phase for the determination of tacrolimus, sirolimus and cyclosporin A in whole blood by high-performance liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041005
-
Activation of an autoregulated protein kinase by conditional protein splicing.
Angewandte Chemie (International ed. in English) 20041004
-
Directing flux in glycan biosynthetic pathways with a small molecule switch.
Chembiochem : a European journal of chemical biology 20041004
-
Human placental taurine transporter in uncomplicated and IUGR pregnancies: cellular localization, protein expression, and regulation.
American journal of physiology. Regulatory, integrative and comparative physiology 20041001
-
Simple extraction protocol for analysis of immunosuppressant drugs in whole blood.
Clinical chemistry 20041001
-
Tolerability and steady-state pharmacokinetics of everolimus in maintenance renal transplant patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041001
-
Sirolimus-associated hepatotoxicity in liver transplantation.
The Annals of pharmacotherapy 20041001
-
Alterations in glucose metabolism by cyclosporine in rat brain slices link to oxidative stress: interactions with mTOR inhibitors.
British journal of pharmacology 20041001
-
Effect of sirolimus withdrawal in patients with deteriorating renal function.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041001
-
What is the calcineurin inhibitor of choice for pediatric renal transplantation?
Pediatric transplantation 20041001
-
Current immunosuppressive agents in pediatric renal transplantation: efficacy, side-effects and utilization.
Pediatric transplantation 20041001
-
Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway.
Annals of oncology : official journal of the European Society for Medical Oncology 20041001
-
Echolucent neointimal hyperplasia 'dark wall' after sirolimus eluting stent implantation.
Heart (British Cardiac Society) 20041001
-
Routine sirolimus eluting stent implantation for unselected in-stent restenosis: insights from the rapamycin eluting stent evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry.
Heart (British Cardiac Society) 20041001
-
Mammalian target of rapamycin and 3-phosphatidylinositol 3-kinase pathway inhibition enhances growth inhibition of transforming growth factor-beta1 in prostate cancer cells.
The Journal of urology 20041001
-
Sirolimus-based immunosuppression for liver transplantation in the presence of extended criteria for hepatocellular carcinoma.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20041001
-
Hepatocellular cancer, transplantation, and sirolimus.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20041001
-
[Sirolimus-eluting stents for the treatment of symptomatic extracranial vertebral artery stenoses: early experience and 6-month follow-up].
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 20041001
-
New insights into drug absorption: studies with sirolimus.
Therapeutic drug monitoring 20041001
-
Everolimus therapeutic concentration range defined from a prospective trial with reduced-exposure cyclosporine in de novo kidney transplantation.
Therapeutic drug monitoring 20041001
-
Raptor protein contains a caspase-like domain.
Trends in biochemical sciences 20041001
-
Human cytomegalovirus infection induces rapamycin-insensitive phosphorylation of downstream effectors of mTOR kinase.
Journal of virology 20041001
-
Effectiveness of sirolimus-eluting stent implantation for the treatment of coronary artery disease in octogenarians.
The American journal of cardiology 20041001
-
Comparison of acute and long-term results and underlying mechanisms from sirolimus-eluting stent implantation for the treatment of in-stent restenosis and recurrent in-stent restenosis in patients in whom intracoronary radiation failed as assessed by intravascular ultrasound.
The American journal of cardiology 20041001
-
Ischemia-reperfusion induces glomerular and tubular activation of proinflammatory and antiapoptotic pathways: differential modulation by rapamycin.
Journal of the American Society of Nephrology : JASN 20041001
-
PP2A phosphatase activity is required for stress and Tor kinase regulation of yeast stress response factor Msn2p.
Eukaryotic cell 20041001
-
Pharmacokinetics of rapamycin-eluting stents in miniswine coronary model.
Chinese medical journal 20041001
-
Drug-eluting stents: some bare facts.
Lancet (London, England) 20041001
-
Late thrombosis in drug-eluting coronary stents after discontinuation of antiplatelet therapy.
Lancet (London, England) 20041001
-
Drug-eluting stents: from randomized trials to the real world.
Minerva cardioangiologica 20041001
-
Coronary bifurcation stenting. Current techniques, outcome and possible future developments.
Minerva cardioangiologica 20041001
-
Saphenous vein graft disease.
Minerva cardioangiologica 20041001
-
Drug-eluting stents: the beginning of the end of restenosis?
Cleveland Clinic journal of medicine 20041001
-
[Drug eluting stents--end of restenosis?].
Vnitrni lekarstvi 20041001
-
[Immunossupresive drugs in renal transplantation].
Polskie Archiwum Medycyny Wewnetrznej 20041001
-
Medical devices; clinical chemistry and clinical toxicology devices; classification of sirolimus test system devices. Final rule.
Federal register 20040930
-
Akt-1 expression level regulates CNS precursors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20040929
-
Active role of chimerism in transplantation tolerance induced by antilymphocyte serum, sirolimus, and bone-marrow-cell infusion.
Transplantation 20040927
-
The selective use of basiliximab versus thymoglobulin in combination with sirolimus for cadaveric renal transplant recipients at low risk versus high risk for delayed graft function.
Transplantation 20040927
-
Correlation between human leukocyte antigen antibody production and serum creatinine in patients receiving sirolimus monotherapy after Campath-1H induction.
Transplantation 20040927
-
Sirolimus-induced interstitial pneumonitis after renal transplantation.
Transplantation 20040927
-
Mammalian target of rapamycin inhibition as therapy for hematologic malignancies.
Cancer 20040915
-
Late coronary thrombosis secondary to a sirolimus-eluting stent.
Circulation 20040914
-
Uth1p is involved in the autophagic degradation of mitochondria.
The Journal of biological chemistry 20040910
-
Progressive changes in Met-dependent signaling in a human ovarian surface epithelial model of malignant transformation.
Experimental cell research 20040910
-
NPR1 kinase and RSP5-BUL1/2 ubiquitin ligase control GLN3-dependent transcription in Saccharomyces cerevisiae.
The Journal of biological chemistry 20040903
-
Regulation of adipocyte differentiation and insulin action with rapamycin.
Biochemical and biophysical research communications 20040903
-
Both mitogen-activated protein kinase and phosphatidylinositol 3-kinase signalling are required in epidermal growth factor-induced human trophoblast migration.
Molecular human reproduction 20040901
-
Sirolimus for GVHD prophylaxis in allogeneic stem cell transplantation.
Bone marrow transplantation 20040901
-
Trace analysis of rapamycin in human blood by micellar electrokinetic chromatography.
Analytical and bioanalytical chemistry 20040901
-
The Cypher stent: no longer efficacious at three months in the porcine model?
Cardiovascular research 20040901
-
Long-term effects of polymer-based, slow-release, sirolimus-eluting stents in a porcine coronary model.
Cardiovascular research 20040901
-
CYP3A4 and P-glycoprotein activity in healthy controls and transplant patients on cyclosporin vs. tacrolimus vs. sirolimus.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040901
-
Sirolimus-induced leukocytoclastic vasculitis: the second case reported.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040901
-
The use of drug eluting stents in single and multivessel disease: results from a single centre experience.
Heart (British Cardiac Society) 20040901
-
Sirolimus eluting stent implantation for patients with multivessel disease: rationale for the Arterial Revascularisation Therapies Study part II (ARTS II).
Heart (British Cardiac Society) 20040901
-
Prevention of restenosis after coronary angioplasty.
Current opinion in cardiology 20040901
-
ANG II activates effectors of mTOR via PI3-K signaling in human coronary smooth muscle cells.
American journal of physiology. Heart and circulatory physiology 20040901
-
Synovial fibroblasts from patients with rheumatoid arthritis, like fibroblasts from Graves' disease, express high levels of IL-16 when treated with Igs against insulin-like growth factor-1 receptor.
Journal of immunology (Baltimore, Md. : 1950) 20040901
-
Preservation of graft function in low-risk living kidney transplant recipients treated with a combination of sirolimus and cyclosporine.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040901
-
Clinical and angiographic outcome after sirolimus-eluting stent implantation in aorto-ostial lesions.
Journal of the American College of Cardiology 20040901
-
Type D personality predicts death or myocardial infarction after bare metal stent or sirolimus-eluting stent implantation: a Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry substudy.
Journal of the American College of Cardiology 20040901
-
Effect of sirolimus on renal ischaemia/reperfusion injury in normotensive and hypertensive rats.
Transplant international : official journal of the European Society for Organ Transplantation 20040901
-
Role of siroliumus, a novel immunosuppressive drug in heart and lung transplantation.
Respiratory medicine 20040901
-
5-HT stimulates eEF2 dephosphorylation in a rapamycin-sensitive manner in Aplysia neurites.
Journal of neurochemistry 20040901
-
Elective sirolimus-eluting stent implantation for multivessel disease involving significant LAD stenosis: one-year clinical outcomes of 99 consecutive patients--the Rotterdam experience.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040901
-
Single-digit target vessel revascularization in multivessel coronary interventions with sirolimus-eluting stents: goodbye to coronary bypass grafting.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040901
-
Bifurcation disease: optimal angiographic result yet suboptimal long-term outcome.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040901
-
Drug-eluting stents: caution and concerns for long-term outcome.
Coronary artery disease 20040901
-
Rapamycin-sensitive induction of eukaryotic initiation factor 4F in regenerating mouse liver.
Hepatology (Baltimore, Md.) 20040901
-
Prolyl isomerases in yeast.
Frontiers in bioscience : a journal and virtual library 20040901
-
Difficulty in establishing sirolimus therapy as a cause of interstitial pneumonitis in renal-transplant recipients.
Journal of the Formosan Medical Association = Taiwan yi zhi 20040901
-
[Drug-coated stents. Where do we stand in 2004?].
Zeitschrift fur Kardiologie 20040901
-
[When are drug-eluting stents effective? A critical analysis of the presently available data].
Zeitschrift fur Kardiologie 20040901
-
Drug-eluting stents: is it the beginning of the end for coronary artery bypass surgery?
Chinese medical journal 20040901
-
Rapamycin-eluting stents for the treatment of unprotected left main coronary disease.
American heart journal 20040901
-
Current and future immunosuppressive strategies in renal transplantation.
Pharmacotherapy 20040901
-
Sirolimus (rapamycin) reduces the incidence of acute rejection episodes in renal transplantation: an initial experience in Taiwan.
Transplantation proceedings 20040901
-
Sirolimus in chronic allograft nephropathy.
Transplantation proceedings 20040901
-
Is sirolimus a safe alternative to reduce or eliminate calcineurin inhibitors in chronic allograft nephropathy in kidney transplantation?
Transplantation proceedings 20040901
-
Pharmacokinetic variability of sirolimus in Taiwanese renal transplant recipients.
Transplantation proceedings 20040901
-
Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity.
The Journal of biological chemistry 20040827
-
Long-term outcome of sirolimus rescue in kidney-pancreas transplantation.
Transplantation 20040827
-
Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways.
Circulation research 20040820
-
[PTCA with drug eluting stent. 90% fewer restenoses in high risk patients].
MMW Fortschritte der Medizin 20040819
-
Randomized, double-blind, placebo-controlled trial of oral sirolimus for restenosis prevention in patients with in-stent restenosis: the Oral Sirolimus to Inhibit Recurrent In-stent Stenosis (OSIRIS) trial.
Circulation 20040817
-
Rapid simultaneous quantification of immunosuppressants in transplant patients by turbulent flow chromatography combined with tandem mass spectrometry.
Clinica chimica acta; international journal of clinical chemistry 20040816
-
Ras, PI3-kinase and mTOR signaling in cardiac hypertrophy.
Cardiovascular research 20040815
-
Acute nephrotoxicity of tacrolimus and sirolimus in renal isografts: differential intragraft expression of transforming growth factor-beta1 and alpha-smooth muscle actin.
Transplantation 20040815
-
Differential effects of everolimus and cyclosporine A on intimal alpha-actin-positive cell dynamics of carotid allografts in mice.
Transplantation 20040815
-
Comparison of outcomes after delayed graft function: sirolimus-based versus other calcineurin-inhibitor sparing induction immunosuppression regimens.
Transplantation 20040815
-
[Immunosuppression with sirolimus so donor kidneys survive longer].
MMW Fortschritte der Medizin 20040805
-
Cost-effectiveness of sirolimus-eluting stents for treatment of complex coronary stenoses: results from the Sirolimus-Eluting Balloon Expandable Stent in the Treatment of Patients With De Novo Native Coronary Artery Lesions (SIRIUS) trial.
Circulation 20040803
-
Economics of sirolimus-eluting stents: drug-eluting stents have really arrived.
Circulation 20040803
-
Marked malapposition and aneurysm formation after sirolimus-eluting coronary stent implantation.
Circulation 20040803
-
G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells.
American journal of physiology. Cell physiology 20040801
-
Two-year incidence of malignancy in sirolimus-treated renal transplant recipients: results from five multicenter studies.
Clinical transplantation 20040801
-
Cross-talk between the survival kinases during early reperfusion: its contribution to ischemic preconditioning.
Cardiovascular research 20040801
-
Late incomplete lesion coverage following Cypher stent deployment for diffuse right coronary artery stenosis.
Heart (British Cardiac Society) 20040801
-
Using established immunosuppressant therapy effectively: lessons from the measurement of mycophenolic acid plasma concentrations.
Therapeutic drug monitoring 20040801
-
Improvement in renal function and rejection control in pediatric liver transplant recipients with the introduction of sirolimus.
Pediatric transplantation 20040801
-
Pilot randomized study of early tacrolimus withdrawal from a regimen with sirolimus plus tacrolimus in kidney transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040801
-
Therapeutic drug monitoring of sirolimus: effect of concomitant immunosuppressive therapy and optimization of drug dosing.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040801
-
Effectiveness of sirolimus-eluting stent implantation for treatment of in-stent restenosis after brachytherapy failure.
The American journal of cardiology 20040801
-
The current status of stent placement in small coronary arteries < 3.0 mm in diameter.
The Journal of invasive cardiology 20040801
-
Contemporary treatment of small-vessel disease.
The Journal of invasive cardiology 20040801
-
Rapamycin-mediated induction of gamma-globin mRNA accumulation in human erythroid cells.
British journal of haematology 20040801
-
Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway.
Developmental cell 20040801
-
Rapamycin suppresses experimental aortic aneurysm growth.
Journal of vascular surgery 20040801
-
Aortic eNOS expression and phosphorylation in Apo-E knockout mice: differing effects of rapamycin and simvastatin.
Surgery 20040801
-
Oral rapamycin to prevent human coronary stent restenosis: a pilot study.
American heart journal 20040801
-
Are drug-eluting stents a panacea for patients with coronary heart disease?
Lancet (London, England) 20040801
-
A hierarchical Bayesian meta-analysis of randomised clinical trials of drug-eluting stents.
Lancet (London, England) 20040801
-
Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte.
The Journal of biological chemistry 20040730
-
Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt.
Oncogene 20040729
-
AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth.
Oncogene 20040729
-
Treatment of left anterior descending coronary artery disease with sirolimus-eluting stents.
Circulation 20040727
-
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.
Current biology : CB 20040727
-
A retrospective review of liver transplant patients treated with sirolimus from a single center: an analysis of sirolimus-related complications.
Transplantation 20040727
-
Everolimus-induced drug fever after heart transplantation.
Transplantation 20040727
-
Evidence for cyclin D3 as a novel target of rapamycin in human T lymphocytes.
The Journal of biological chemistry 20040723
-
In vitro study of release mechanisms of paclitaxel and rapamycin from drug-incorporated biodegradable stent matrices.
Journal of controlled release : official journal of the Controlled Release Society 20040723
-
An activated mTOR mutant supports growth factor-independent, nutrient-dependent cell survival.
Oncogene 20040722
-
Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent.
The Journal of biological chemistry 20040716
-
Aldosterone rapidly activates Src kinase in M-1 cells involving the mineralocorticoid receptor and HSP84.
FEBS letters 20040716
-
Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20040714
-
Images in cardiovascular medicine. Vascular healing 4 years after the implantation of sirolimus-eluting stent in humans: a histopathological examination.
Circulation 20040706
-
Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus.
The Journal of biological chemistry 20040702
-
Association of rapamycin and co-stimulation blockade using anti-B7 antibodies in renal allotransplantation in baboons.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040701
-
Reversing drug resistance in vivo.
Cell cycle (Georgetown, Tex.) 20040701
-
Biological aspects of radiation and drug-eluting stents for the prevention of restenosis.
Cardiovascular research 20040701
-
Sirolimus impairs gonadal function in heart transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040701
-
Successful simultaneous islet-kidney transplantation using a steroid-free immunosuppression: two-year follow-up.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040701
-
Different costimulatory and growth factor requirements for CD4+ and CD8+ T cell-mediated rejection.
Journal of immunology (Baltimore, Md. : 1950) 20040701
-
Differential expression of chemokines and chemokine receptors in murine islet allografts: the role of CCR2 and CCR5 signaling pathways.
Journal of the American Society of Nephrology : JASN 20040701
-
Effectiveness of sirolimus-Eluting stent implantation for coronary narrowings <50% in diameter.
The American journal of cardiology 20040701
-
Restenosis rates following bifurcation stenting with sirolimus-eluting stents for de novo narrowings.
The American journal of cardiology 20040701
-
Drug-eluting stents: the panacea for restenosis?
Singapore medical journal 20040701
-
A stent is not just a stent: Stent construction and design do matter in its clinical performance.
Singapore medical journal 20040701
-
Clinical outcomes for sirolimus-eluting stent implantation and vascular brachytherapy for the treatment of in-stent restenosis.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040701
-
'At least but not at last' equivalent!
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040701
-
Vascular brachytherapy vs. drug-eluting stents for the treatment of in-stent restenosis: the jury's still out.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040701
-
Elective sirolimus-eluting stent implantation for left main coronary artery disease: six-month angiographic follow-up and 1-year clinical outcome.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040701
-
Immunosuppression and modulation in liver transplantation.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040701
-
Rapamycin and chronic lung rejection.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040701
-
[Antiproliferative drug-eluting stents: systematic review of the benefits and estimate of economic impact].
Revista espanola de cardiologia 20040701
-
Drug-eluting stents: the end of restenosis?
Annals of the Academy of Medicine, Singapore 20040701
-
[Inhibition of hypoxia-inducible factor 1alpha expression and tumor growth in SKOV3 ovarian cancer model by sirolimus].
Zhonghua fu chan ke za zhi 20040701
-
The mTOR/p70S6K signal transduction pathway plays a role in cardiac hypertrophy and influences expression of myosin heavy chain genes in vivo.
Cardiovascular drugs and therapy 20040701
-
Isolation, structure determination and biological activity of 15-deoxo-7,32-O-didesmethylrapamycin from the soil actinomycete LL-D45042.
The Journal of antibiotics 20040701
-
Pro- and anti-cancer effects of immunosuppressive agents used in organ transplantation.
Transplantation 20040627
-
Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload.
Circulation 20040622
-
Regulation of translation elongation and phosphorylation of eEF2 in rat pancreatic acini.
Biochemical and biophysical research communications 20040618
-
Mechanical stimuli regulate rapamycin-sensitive signalling by a phosphoinositide 3-kinase-, protein kinase B- and growth factor-independent mechanism.
The Biochemical journal 20040615
-
New target, new drug, old paradigm.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040615
-
Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040615
-
Angiographic and volumetric intravascular ultrasound comparison between direct sirolimus-eluting stent implantation versus predilation.
The American journal of cardiology 20040615
-
Stable expression of small interfering RNA sensitizes TEL-PDGFbetaR to inhibition with imatinib or rapamycin.
The Journal of clinical investigation 20040615
-
New immunosuppressant class not without serious concerns.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040615
-
Intraprocedural stent thrombosis during implantation of sirolimus-eluting stents.
Circulation 20040608
-
96-Well liquid-liquid extraction liquid chromatography-tandem mass spectrometry method for the quantitative determination of ABT-578 in human blood samples.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040605
-
Interferon alpha-induced apoptosis in tumor cells is mediated through the phosphoinositide 3-kinase/mammalian target of rapamycin signaling pathway.
The Journal of biological chemistry 20040604
-
Degradation of PKB/Akt protein by inhibition of the VEGF receptor/mTOR pathway in endothelial cells.
Oncogene 20040603
-
Significant reduction in restenosis after the use of sirolimus-eluting stents in the treatment of chronic total occlusions.
Journal of the American College of Cardiology 20040602
-
Impact of final stent dimensions on long-term results following sirolimus-eluting stent implantation: serial intravascular ultrasound analysis from the sirius trial.
Journal of the American College of Cardiology 20040602
-
Rab7 is required for the normal progression of the autophagic pathway in mammalian cells.
Journal of cell science 20040601
-
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.
Nature genetics 20040601
-
Increased risk of thrombotic microangiopathy in patients receiving a cyclosporin-sirolimus combination.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040601
-
Sirolimus-based therapy following early cyclosporine withdrawal provides significantly improved renal histology and function at 3 years.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040601
-
Outcome at 3 years with a prednisone-free maintenance regimen: a single-center experience with 349 kidney transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040601
-
Sirolimus-induced angioedema.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040601
-
Post-sirolimus-eluting stent restenosis treated with repeat percutaneous intervention: late angiographic and clinical outcomes.
Circulation 20040601
-
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.
Nature medicine 20040601
-
HIV infection of primary human T cells is determined by tunable thresholds of T cell activation.
European journal of immunology 20040601
-
Sirolimus- versus paclitaxel-eluting stents in patients with stenosis in a native coronary artery.
Expert opinion on pharmacotherapy 20040601
-
Creatine kinase-myocardial band isoenzyme elevation after percutaneous coronary interventions using sirolimus-eluting stents.
The American journal of cardiology 20040601
-
TORward AKTually useful mouse models.
Nature medicine 20040601
-
Sirolimus for pediatric liver transplant recipients with post-transplant lymphoproliferative disease and hepatoblastoma.
Pediatric transplantation 20040601
-
Immunosuppressive drug monitoring of sirolimus and cyclosporine in pediatric patients.
Clinical biochemistry 20040601
-
First experience with rapamycin-based immunosuppression to improve kidney function after heart transplantation.
The Thoracic and cardiovascular surgeon 20040601
-
The impact of Sirolimus Eluting stents in interventional cardiology.
International journal of cardiology 20040601
-
Procedural and long-term results of sirolimus-eluting stent in patients at high risk for restenosis.
Minerva cardioangiologica 20040601
-
Pharmacokinetics of sirolimus in heart transplant recipients with chronic renal impairment.
Transplantation proceedings 20040601
-
Chronic allograft nephropathy: pathogenesis and management of an important posttransplant complication.
Progress in transplantation (Aliso Viejo, Calif.) 20040601
-
Future immunosuppressive agents in solid-organ transplantation.
Progress in transplantation (Aliso Viejo, Calif.) 20040601
-
Strategies to prevent chronic allograft nephropathy in kidney transplantation: focus on calcineurin inhibitors.
Progress in transplantation (Aliso Viejo, Calif.) 20040601
-
The efficacy and limitations of sirolimus conversion in liver transplant patients who develop renal dysfunction on calcineurin inhibitors.
Digestive diseases and sciences 20040601
-
Eluting stents: an effective, promising solution?
Italian heart journal : official journal of the Italian Federation of Cardiology 20040601
-
Sirolimus and mycophenolate mofetil as calcineurin inhibitor-free immunosuppression in a cardiac transplant patient with chronic renal failure.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040601
-
Fatal interstitial pneumonitis associated with sirolimus therapy in a heart transplant recipient.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040601
-
[Involvement of hnRNP in selective translation inhibition of mRNA by rapamycin].
The Japanese journal of antibiotics 20040601
-
[Effect of EM201, an in vivo metabolite of erythromycin (EM), on signal transduction of IL-2 receptor].
The Japanese journal of antibiotics 20040601
-
Dimerization is required for activation of eIF2 kinase Gcn2 in response to diverse environmental stress conditions.
The Journal of biological chemistry 20040528
-
Mammalian target of rapamycin positively regulates collagen type I production via a phosphatidylinositol 3-kinase-independent pathway.
The Journal of biological chemistry 20040528
-
Metabolic interaction between cyclosporine and sirolimus.
Transplantation 20040527
-
Wound-healing complications after kidney transplantation: a prospective, randomized comparison of sirolimus and tacrolimus.
Transplantation 20040527
-
Impact of sirolimus-eluting stents on outcome in diabetic patients: a SIRIUS (SIRolImUS-coated Bx Velocity balloon-expandable stent in the treatment of patients with de novo coronary artery lesions) substudy.
Circulation 20040518
-
Incidence of thrombotic stent occlusion during the first three months after sirolimus-eluting stent implantation in 500 consecutive patients.
The American journal of cardiology 20040515
-
Perturbed IFN-gamma-Jak-signal transducers and activators of transcription signaling in tuberous sclerosis mouse models: synergistic effects of rapamycin-IFN-gamma treatment.
Cancer research 20040515
-
Rapamycin protects allografts from rejection while simultaneously attacking tumors in immunosuppressed mice.
Transplantation 20040515
-
An update on clinical outcomes in heart and lung transplantation.
Transplantation 20040515
-
Involvement of integrins and Src in insulin signaling toward autophagic proteolysis in rat liver.
The Journal of biological chemistry 20040514
-
Critical role of T-loop and H-motif phosphorylation in the regulation of S6 kinase 1 by the tuberous sclerosis complex.
The Journal of biological chemistry 20040514
-
Essential role of PDGFRalpha-p70S6K signaling in mesenchymal cells during therapeutic and tumor angiogenesis in vivo: role of PDGFRalpha during angiogenesis.
Circulation research 20040514
-
'Me-too' products--friend or foe?
The New England journal of medicine 20040513
-
Six- and twelve-month results from first human experience using everolimus-eluting stents with bioabsorbable polymer.
Circulation 20040511
-
How many grails do we need?
Circulation 20040511
-
Everolimus stent proves effective.
Circulation 20040511
-
Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals.
The Journal of biological chemistry 20040507
-
Images in cardiovascular medicine. Coronary uptake of gallium-67 citrate after implantation of sirolimus-eluting stent.
Circulation 20040504
-
Isolation and characterization of pre-rapamycin, the first macrocyclic intermediate in the biosynthesis of the immunosuppressant rapamycin by S. hygroscopicus.
Angewandte Chemie (International ed. in English) 20040503
-
Early experiences and clinical implications of restenosis and drug-eluting stents: Part 2.
The Annals of pharmacotherapy 20040501
-
Pharmacokinetics of sirolimus and tacrolimus in pediatric transplant patients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040501
-
Sirolimus eluting stent aborted recurrent distal left main in-stent restenosis involving bifurcation.
Heart (British Cardiac Society) 20040501
-
Optimizing the immunosuppressive regimen in heart transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040501
-
Effectiveness of the sirolimus-eluting stent in the treatment of patients with a prior history of coronary artery bypass graft surgery.
Coronary artery disease 20040501
-
Acute rapamycin nephrotoxicity in native kidneys of patients with chronic glomerulopathies.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040501
-
Use of sirolimus-eluting coronary stents in routine clinical practice.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040501
-
Day in and day out.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040501
-
Economic evaluation of everolimus versus mycophenolate mofetil in combination with cyclosporine and prednisolone in de novo renal transplant recipients.
Transplant international : official journal of the European Society for Organ Transplantation 20040501
-
Local application of rapamycin inhibits neointimal hyperplasia in experimental vein grafts.
The Annals of thoracic surgery 20040501
-
Sirolimus and tacrolimus without methotrexate as graft-versus-host disease prophylaxis after matched related donor peripheral blood stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20040501
-
Rapamycin-associated post-transplantation glomerulonephritis and its remission after reintroduction of calcineurin-inhibitor therapy.
Transplant international : official journal of the European Society for Organ Transplantation 20040501
-
Sirolimus-induced hyperlipidaemia in liver transplant recipients is not dose-dependent.
Alimentary pharmacology & therapeutics 20040501
-
The TOR pathway: a target for cancer therapy.
Nature reviews. Cancer 20040501
-
Clinical impact of stent construction and design in percutaneous coronary intervention.
American heart journal 20040501
-
Airway anastomosis complications in de novo lung transplantation with sirolimus-based immunosuppression.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040501
-
[Active stents: towards total prevention of restenosis?].
Pathologie-biologie 20040501
-
Effectiveness of the sirolimus-eluting stent in the treatment of saphenous vein graft disease.
The Journal of invasive cardiology 20040501
-
Drug-eluting stents and saphenous vein graft intervention.
The Journal of invasive cardiology 20040501
-
Rapamycin inhibits release of tumor necrosis factor-alpha from human vascular smooth muscle cells.
The American surgeon 20040501
-
Chemical dimerizers and three-hybrid systems: scanning the proteome for targets of organic small molecules.
Chemistry & biology 20040501
-
Selective modulation of some forms of schaffer collateral-CA1 synaptic plasticity in mice with a disruption of the CPEB-1 gene.
Learning & memory (Cold Spring Harbor, N.Y.) 20040501
-
Sirolimus-eluting stent implantation in a heart transplant recipient.
Italian heart journal : official journal of the Italian Federation of Cardiology 20040501
-
Rapamycin even when combined with cyclosporine attenuates tumor growth but does not induce regression of established walker sarcomas.
Transplantation proceedings 20040501
-
Immunosuppression in pancreas transplantation: mycophenolate mofetil versus sirolimus.
Transplantation proceedings 20040501
-
Long-term outcome of sirolimus rescue in kidney-pancreas transplantation.
Transplantation proceedings 20040501
-
Islet of Langerhans allogeneic transplantation at the University of Geneva in the steroid free era in islet after kidney and simultaneous islet-kidney transplantations.
Transplantation proceedings 20040501
-
Glucose-induced binding of the polypyrimidine tract-binding protein (PTB) to the 3'-untranslated region of the insulin mRNA (ins-PRS) is inhibited by rapamycin.
Molecular and cellular biochemistry 20040501
-
High-dose bolus tirofiban and sirolimus eluting stent versus abiciximab and bare metal stent in acute myocardial infarction (STRATEGY) study--protocol design and demography of the first 100 patients.
Cardiovascular drugs and therapy 20040501
-
[From sirolimus to the Cypher stent: stages of the victory against restenosis].
Annales de cardiologie et d'angeiologie 20040501
-
[Sirolimus endoprosthesis: data from the RAVEL and the SIRIUS study].
Annales de cardiologie et d'angeiologie 20040501
-
[The E-SIRIUS and the new SIRIUS clinical trials].
Annales de cardiologie et d'angeiologie 20040501
-
[The e-Cypher registry: objectives and organization].
Annales de cardiologie et d'angeiologie 20040501
-
[The national registry EVASTENT: cost-effectiveness analysis of the sirolimus active stent in diabetic and non-diabetic patients].
Annales de cardiologie et d'angeiologie 20040501
-
[BRIDGE registry (safety and efficacy registry Bx Cyper stent in the RevascularIzation of patients with siGnificative risk of rEstenosis): protocol description and preliminary results].
Annales de cardiologie et d'angeiologie 20040501
-
[Sirolimus-releasing coronary stent: lessons from the Rotterdam experience].
Annales de cardiologie et d'angeiologie 20040501
-
[Cypher stent: the German registry. Results of the German prospective multicenter registry on Cypher].
Annales de cardiologie et d'angeiologie 20040501
-
[The Cypher stent: most recent news of the 2004 Congress of the American College of Cardiology].
Annales de cardiologie et d'angeiologie 20040501
-
[Cypher: ongoing studies].
Annales de cardiologie et d'angeiologie 20040501
-
[The Siro-ISR registry: treatment of intra-stent restenosis with the sirolimus stent in the real world].
Annales de cardiologie et d'angeiologie 20040501
-
[Cypher stent: upcoming clinical studies].
Annales de cardiologie et d'angeiologie 20040501
-
['Active' endoprosthesis with in situ release of an antimitotic or cytostatic drug: a revolution that cannot do without thought].
Annales de cardiologie et d'angeiologie 20040501
-
Actin cytoskeleton is required for nuclear accumulation of Gln3 in response to nitrogen limitation but not rapamycin treatment in Saccharomyces cerevisiae.
The Journal of biological chemistry 20040430
-
Stent thrombosis after successful sirolimus-eluting stent implantation.
Circulation 20040427
-
Synergistic effects of sirolimus with cyclosporine and tacrolimus: analysis of immunosuppression on lymphocyte proliferation and activation in rat whole blood.
Transplantation 20040427
-
Sirolimus-associated pulmonary toxicity.
Transplantation 20040427
-
Comparison of sirolimus-based calcineurin inhibitor-sparing and calcineurin inhibitor-free regimens in cadaveric renal transplantation.
Transplantation 20040427
-
Niban gene is commonly expressed in the renal tumors: a new candidate marker for renal carcinogenesis.
Oncogene 20040422
-
Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases.
The EMBO journal 20040421
-
Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status.
The Journal of biological chemistry 20040416
-
Opioid-induced cardioprotection occurs via glycogen synthase kinase beta inhibition during reperfusion in intact rat hearts.
Circulation research 20040416
-
TOR kinase and Ran are downstream from PI3K/Akt in H2O2-induced mitosis.
Journal of cellular biochemistry 20040415
-
The novel cyclophilin binding compound, sanglifehrin A, disassociates G1 cell cycle arrest from tolerance induction.
Journal of immunology (Baltimore, Md. : 1950) 20040415
-
Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone.
Blood 20040415
-
Lymphedema associated with sirolimus in renal transplant recipients.
Transplantation 20040415
-
TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae.
The Journal of biological chemistry 20040409
-
Treatment of multivessel coronary artery disease with sirolimus-eluting stent implantation: immediate and mid-term results.
Journal of the American College of Cardiology 20040407
-
Mammalian target of rapamycin regulates IRS-1 serine 307 phosphorylation.
Biochemical and biophysical research communications 20040402
-
New rapamycin derivatives by precursor-directed biosynthesis.
Chembiochem : a European journal of chemical biology 20040402
-
Rapamycin control of exocrine protein levels in saliva after adenoviral vector-mediated gene transfer.
Gene therapy 20040401
-
Arginine and Leucine regulate p70 S6 kinase and 4E-BP1 in intestinal epithelial cells.
International journal of molecular medicine 20040401
-
IL2-dependent phosphorylation of 40S ribosomal protein S6 is controlled by PI-3K/mTOR signalling in CTLL2 cells.
International journal of molecular medicine 20040401
-
Multiple combination therapies involving blockade of ICOS/B7RP-1 costimulation facilitate long-term islet allograft survival.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040401
-
Everolimus with optimized cyclosporine dosing in renal transplant recipients: 6-month safety and efficacy results of two randomized studies.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040401
-
An investigation into signal transduction mechanisms involved in insulin-induced long-term depression in the CA1 region of the hippocampus.
Journal of neurochemistry 20040401
-
Role of FKBP12.6 in hypoxia- and norepinephrine-induced Ca2+ release and contraction in pulmonary artery myocytes.
Cell calcium 20040401
-
Rapamycin effects transcriptional programs in smooth muscle cells controlling proliferative and inflammatory properties.
Molecular pharmacology 20040401
-
Safety and pharmacokinetics of ascending single doses of sirolimus (Rapamune, rapamycin) in pediatric patients with stable chronic renal failure undergoing dialysis.
Pediatric transplantation 20040401
-
Short sirolimus half-life in pediatric renal transplant recipients on a calcineurin inhibitor-free protocol.
Pediatric transplantation 20040401
-
Very long sirolimus-eluting stent implantation for de novo coronary lesions.
The American journal of cardiology 20040401
-
Local drug delivery in restenosis injury: thermoresponsive co-polymers as potential drug delivery systems.
Pharmacology & therapeutics 20040401
-
Immunosuppressants and skin cancer in transplant patients: focus on rapamycin.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20040401
-
Clinical and angiographic outcomes after overdilatation of undersized sirolimus-eluting stents with largely oversized balloons: an observational study.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040401
-
Overstretching undersized drug-eluting stents: a temporary solution.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040401
-
Sirolimus-associated diffuse alveolar hemorrhage.
Mayo Clinic proceedings 20040401
-
Dissociation of raptor from mTOR is a mechanism of rapamycin-induced inhibition of mTOR function.
Genes to cells : devoted to molecular & cellular mechanisms 20040401
-
Sirolimus-eluting stents in the canine cerebral vasculature: a prospective, randomized, blinded assessment of safety and vessel response.
Journal of neurosurgery 20040401
-
'Real life' use of sirolimus-eluting coronary stents in Germany. Results from the prospective multi-centre German Cypher Registry.
Zeitschrift fur Kardiologie 20040401
-
Sirolimus increases transforming growth factor-beta1 expression and potentiates chronic cyclosporine nephrotoxicity.
Kidney international 20040401
-
Sirolimus in kidney transplantation from marginal donors.
Transplantation proceedings 20040401
-
Platelet-Independent defect in hemostasis associated with sirolimus use.
Transplantation proceedings 20040401
-
Severe rhabdomyolysis and acute renal failure in a kidney transplant patient treated with tacrolimus and chimaeric CD25 monoclonal antibody.
Transplantation proceedings 20040401
-
PI3-kinase and TOR: PIKTORing cell growth.
Seminars in cell & developmental biology 20040401
-
Islet allograft survival in nonhuman primates immunosuppressed with basiliximab, RAD, and FTY720.
Transplantation 20040327
-
Therapeutic drug monitoring for sirolimus in whole blood of organ transplants by high-performance liquid chromatography with ultraviolet detection.
Journal of chromatography. A 20040326
-
Clinical, angiographic, and procedural predictors of angiographic restenosis after sirolimus-eluting stent implantation in complex patients: an evaluation from the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) study.
Circulation 20040323
-
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
Biochemical and biophysical research communications 20040319
-
Cancer: survival pathways meet their end.
Nature 20040318
-
Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy.
Nature 20040318
-
Differential regulation of MAP2 and alphaCamKII expression in hippocampal neurones by forskolin and calcium ionophore treatment.
Brain research. Molecular brain research 20040317
-
The Canadian study of the sirolimus-eluting stent in the treatment of patients with long de novo lesions in small native coronary arteries (C-SIRIUS).
Journal of the American College of Cardiology 20040317
-
Sirolimus-eluting stents: does a great stent still need a good interventionalist?
Journal of the American College of Cardiology 20040317
-
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Circulation 20040316
-
Unique, highly proliferative growth phenotype expressed by embryonic and neointimal smooth muscle cells is driven by constitutive Akt, mTOR, and p70S6K signaling and is actively repressed by PTEN.
Circulation 20040316
-
Combination therapy with sirolimus and mycophenolate mofetil: effects on the kidney and on transforming growth factor-beta1.
Transplantation 20040315
-
Conversion to sirolimus: a successful treatment for posttransplantation Kaposi's sarcoma.
Transplantation 20040315
-
Molecular imaging of drug-modulated protein-protein interactions in living subjects.
Cancer research 20040315
-
Rapamycin-induced endothelial cell death and tumor vessel thrombosis potentiate cytotoxic therapy against pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 20040315
-
Gln3 phosphorylation and intracellular localization in nutrient limitation and starvation differ from those generated by rapamycin inhibition of Tor1/2 in Saccharomyces cerevisiae.
The Journal of biological chemistry 20040312
-
Contribution of stent underexpansion to recurrence after sirolimus-eluting stent implantation for in-stent restenosis.
Circulation 20040309
-
Drug-eluting stent restenosis rates?
Circulation 20040309
-
Protein kinase A phosphorylation at serine-2808 of the cardiac Ca2+-release channel (ryanodine receptor) does not dissociate 12.6-kDa FK506-binding protein (FKBP12.6).
Circulation research 20040305
-
The mTOR/p70 S6K1 pathway regulates vascular smooth muscle cell differentiation.
American journal of physiology. Cell physiology 20040301
-
Mammalian target of rapamycin (mTOR) Inhibitors.
Current oncology reports 20040301
-
Rapamycin plays a new role as differentiator of vascular smooth muscle phenotype. focus on 'The mTOR/p70 S6K1 pathway regulates vascular smooth muscle differentiation'.
American journal of physiology. Cell physiology 20040301
-
Evidence for 'lumen sealing' with sirolimus eluting stents in the treatment of complex coronary artery dissection.
Heart (British Cardiac Society) 20040301
-
Long-term benefits with sirolimus-based therapy after early cyclosporine withdrawal.
Journal of the American Society of Nephrology : JASN 20040301
-
Synergistic use of sirolimus-eluting stents and intravascular ultrasound for the treatment of unprotected left main and vein graft disease.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040301
-
Electron microscopic and biochemical study of the effects of rapamycin on glycogen autophagy in the newborn rat liver.
Microscopy research and technique 20040301
-
Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040301
-
Treatment of very small vessels with 2.25-mm diameter sirolimus-eluting stents (from the RESEARCH registry).
The American journal of cardiology 20040301
-
Economic impact of drug-eluting stents on hospital systems: a disease-state model.
American heart journal 20040301
-
Cell signalling of glucagon-like peptide-1 action in rat skeletal muscle.
The Journal of endocrinology 20040301
-
Steroid immunosuppression in kidney transplantation: a passing era.
The Journal of surgical research 20040301
-
Blockage of 2-deoxy-D-ribose-induced angiogenesis with rapamycin counteracts a thymidine phosphorylase-based escape mechanism available for colon cancer under 5-fluorouracil therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 20040301
-
Sirolimus-eluting coronary stent.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040301
-
Renal recovery after conversion to a calcineurin inhibitor-free immunosuppression in late cardiac transplant recipients.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20040301
-
Effects of aerobic exercise training on the protein kinase B (PKB)/mammalian target of rapamycin (mTOR) signaling pathway in aged skeletal muscle.
Experimental gerontology 20040301
-
Use of cyclosporine in renal transplantation.
Transplantation proceedings 20040301
-
Immunosuppression for pancreatic islet transplantation.
Transplantation proceedings 20040301
-
The evolving experience using everolimus in clinical transplantation.
Transplantation proceedings 20040301
-
Experience with everolimus.
Transplantation proceedings 20040301
-
The promise of C2, Simulect, and Certican in heart transplantation.
Transplantation proceedings 20040301
-
Promise of Neoral C2, basiliximab, and everolimus in lung transplantation.
Transplantation proceedings 20040301
-
Rapamycin analogs for stent-based local drug delivery. Everolimus- and tacrolimus-eluting stents.
Herz 20040301
-
ABT-578-eluting stents. The promising successor of sirolimus- and paclitaxel-eluting stent concepts?
Herz 20040301
-
Polymer-sirolimus-eluting stents in de novo lesions.
Herz 20040301
-
[Safety and current indications during 'real life' use of sirolimus-eluting coronary stents in Germany. Results from the prospective multicenter German Cypher Registry].
Herz 20040301
-
Classification and current treatment options of in-stent restenosis. Present status and future perspectives.
Herz 20040301
-
Drug-eluting stents for in-stent restenosis and acute myocardial infarction: present data from nonrandomized studies.
Herz 20040301
-
[Do drug-eluting stents influence the spectrum of coronary artery bypass surgery?].
Herz 20040301
-
Drug eluting stents in the infrainguinal circulation.
Techniques in vascular and interventional radiology 20040301
-
Cardiac allograft vasculopathy: advances in understanding its pathophysiology, prevention, and treatment.
Current opinion in cardiology 20040301
-
Low toxicity immunosuppressive protocols in renal transplantation.
The Keio journal of medicine 20040301
-
Molecule of the month. Everolimus.
Drug news & perspectives 20040301
-
Rpd3p relocation mediates a transcriptional response to rapamycin in yeast.
Chemistry & biology 20040301
-
Dose-dependent inhibition of myointimal hyperplasia by orally administered rapamycin.
Annals of vascular surgery 20040301
-
Amino acids and insulin control autophagic proteolysis through different signaling pathways in relation to mTOR in isolated rat hepatocytes.
The Journal of biological chemistry 20040227
-
Mycophenolate mofetil and sirolimus as calcineurin inhibitor-free immunosuppression for late cardiac-transplant recipients with chronic renal failure.
Transplantation 20040227
-
Paradigm shifts in cardiovascular medicine.
Journal of the American College of Cardiology 20040218
-
Short- and long-term clinical benefit of sirolimus-eluting stents compared to conventional bare stents for patients with acute myocardial infarction.
Journal of the American College of Cardiology 20040218
-
Localized hypersensitivity and late coronary thrombosis secondary to a sirolimus-eluting stent: should we be cautious?
Circulation 20040217
-
Mammalian target of rapamycin inhibition as therapy for hematologic malignancies.
Cancer 20040215
-
Sirolimus and ketoconazole co-prescription in renal transplant recipients.
Transplantation 20040215
-
Intravascular ultrasound study of effects of overlapping sirolimus-eluting stents.
The American journal of cardiology 20040215
-
mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability.
Genes & development 20040215
-
Analysis of 1-year clinical outcomes in the SIRIUS trial: a randomized trial of a sirolimus-eluting stent versus a standard stent in patients at high risk for coronary restenosis.
Circulation 20040210
-
[New devices for coronary interventions in patients with acute coronary syndrome].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20040210
-
[Irritant cough and sub-febrile temperature under immunosuppression].
Praxis 20040204
-
Dead cells don't form tumors: HIF-dependent cytotoxins.
Cell cycle (Georgetown, Tex.) 20040201
-
Novel therapeutic molecular targets for prostate cancer: the mTOR signaling pathway and epidermal growth factor receptor.
The Journal of urology 20040201
-
Mechanistic insights into impaired dendritic cell function by rapamycin: inhibition of Jak2/Stat4 signaling pathway.
Journal of immunology (Baltimore, Md. : 1950) 20040201
-
Regional haemodynamic effects of cyclosporine A, tacrolimus and sirolimus in conscious rats.
British journal of pharmacology 20040201
-
Kissing sirolimus-eluting stents for the treatment of left main coronary artery stenosis.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040201
-
Treatment of long, diffuse in-stent restenosis with sirolimus-eluting stents.
The Journal of invasive cardiology 20040201
-
Effect of sirolimus on infection incidence in liver transplant recipients.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20040201
-
Stent restenosis and the use of drug-eluting stents in patients with diabetes mellitus.
Current diabetes reports 20040201
-
Determinants of rapamycin sensitivity in breast cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 20040201
-
[Is systematic use of drug-eluting stents justified? Arguments in favour].
Revista espanola de cardiologia 20040201
-
[Is systematic use of drug-eluting stents justified? Arguments against].
Revista espanola de cardiologia 20040201
-
[Sirolimus-eluting stents to treat lesions with a high risk of restenosis. Six-month clinical follow-up in the first 100 patients].
Revista espanola de cardiologia 20040201
-
[Use of sirolimus-eluting stents in complex lesions: clinical and angiographic follow-up].
Revista espanola de cardiologia 20040201
-
Inhibition of insulin signaling and adipogenesis by rapamycin: effect on phosphorylation of p70 S6 kinase vs eIF4E-BP1.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20040201
-
Human renal allograft rejection despite the absence of allogeneic passenger leukocytes.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040201
-
Is everolimus useful in preventing allograft rejection and vasculopathy after heart transplant?
Expert opinion on investigational drugs 20040201
-
Drug-eluting stents: a new treatment in the prevention of restenosis. Part I: Experimental studies.
Acta cardiologica 20040201
-
[Thrombosis caused by active rapamycin stents].
Archives des maladies du coeur et des vaisseaux 20040201
-
Everolimus: a proliferation signal inhibitor targeting primary causes of allograft dysfunction.
Drugs of today (Barcelona, Spain : 1998) 20040201
-
Stents put on a new drug coat. The coat is thin and washes off, but offers major protection.
Heart advisor 20040201
-
An open-label randomized trial of the safety and efficacy of sirolimus vs. azathioprine in living related renal allograft recipients receiving cyclosporine and prednisone combination.
Clinical transplantation 20040201
-
Observations regarding the use of sirolimus and tacrolimus in high-risk cadaveric renal transplantation.
Clinical transplantation 20040201
-
Nutrient-dependent and insulin-stimulated phosphorylation of insulin receptor substrate-1 on serine 302 correlates with increased insulin signaling.
The Journal of biological chemistry 20040130
-
The N-terminal domain of yeast Bap2 permease is phosphorylated dependently on the Npr1 kinase in response to starvation.
FEMS microbiology letters 20040130
-
Acceleration of apoptosis in CD4+CD8+ thymocytes by rapamycin accompanied by increased CD4+CD25+ T cells in the periphery.
Transplantation 20040127
-
A randomized long-term trial of tacrolimus and sirolimus versus tacrolimus and mycophenolate mofetil versus cyclosporine (NEORAL) and sirolimus in renal transplantation. I. Drug interactions and rejection at one year.
Transplantation 20040127
-
A randomized long-term trial of tacrolimus/sirolimus versus tacrolimus/mycophenolate mofetil versus cyclosporine (NEORAL)/sirolimus in renal transplantation. II. Survival, function, and protocol compliance at 1 year.
Transplantation 20040127
-
Everolimus and mycophenolate mofetil are potent inhibitors of fibroblast proliferation after lung transplantation.
Transplantation 20040127
-
AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expression.
The Journal of biological chemistry 20040123
-
Sirolimus-eluting coronary stents.
The New England journal of medicine 20040122
-
Sirolimus-eluting coronary stents.
The New England journal of medicine 20040122
-
Unrestricted utilization of sirolimus-eluting stents compared with conventional bare stent implantation in the 'real world': the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) registry.
Circulation 20040120
-
Functional characterization of a maize ribosomal S6 protein kinase (ZmS6K), a plant ortholog of metazoan p70(S6K).
Biochemistry 20040120
-
Bringing reality to drug-eluting stents.
Circulation 20040120
-
'Me-too' products--friend or foe?
The New England journal of medicine 20040115
-
Thrombotic microangiopathy associated with combined sirolimus and tacrolimus immunosuppression after intestinal transplantation.
Transplantation 20040115
-
Rapamycin inhibits cdk4 activation, p 21(WAF1/CIP1) expression and G1-phase progression in transformed mouse fibroblasts.
International journal of cancer 20040110
-
Rapamycin-resistant proliferation of CD8+ T cells correlates with p27kip1 down-regulation and bcl-xL induction, and is prevented by an inhibitor of phosphoinositide 3-kinase activity.
The Journal of biological chemistry 20040109
-
Golgi membranes remain segregated from the endoplasmic reticulum during mitosis in mammalian cells.
Cell 20040109
-
Differential effects of modern immunosuppressive agents on the development of intimal hyperplasia.
Transplant international : official journal of the European Society for Organ Transplantation 20040101
-
The role of phosphatases in TOR signaling in yeast.
Current topics in microbiology and immunology 20040101
-
Nutrient signaling through TOR kinases controls gene expression and cellular differentiation in fungi.
Current topics in microbiology and immunology 20040101
-
The fission yeast TOR proteins and the rapamycin response: an unexpected tale.
Current topics in microbiology and immunology 20040101
-
Plant growth and the TOR pathway.
Current topics in microbiology and immunology 20040101
-
TOR action in mammalian cells and in Caenorhabditis elegans.
Current topics in microbiology and immunology 20040101
-
mTOR signaling to translation.
Current topics in microbiology and immunology 20040101
-
Raptor and mTOR: subunits of a nutrient-sensitive complex.
Current topics in microbiology and immunology 20040101
-
mTOR as a positive regulator of tumor cell responses to hypoxia.
Current topics in microbiology and immunology 20040101
-
Retroviral oncogenes and TOR.
Current topics in microbiology and immunology 20040101
-
mTOR as a target for cancer therapy.
Current topics in microbiology and immunology 20040101
-
CYP3A4-transfected Caco-2 cells as a tool for understanding biochemical absorption barriers: studies with sirolimus and midazolam.
The Journal of pharmacology and experimental therapeutics 20040101
-
Non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95) amplifies ionotropic glutamate receptor signaling in embryonic cerebellar granule neurons by a mechanism involving ryanodine receptors.
Toxicological sciences : an official journal of the Society of Toxicology 20040101
-
Drug-eluting stents. A review of the current literature.
Cardiology in review 20040101
-
mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E.
Molecular and cellular biology 20040101
-
Testosterone concentrations and sirolimus in male renal transplant patients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040101
-
Sirolimus-induced pneumonitis: three cases and a review of the literature.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040101
-
Intravascular ultrasound evaluation after sirolimus eluting stent implantation for de novo and in-stent restenosis lesions.
European heart journal 20040101
-
Addition of sirolimus to cyclosporine delays the recovery from delayed graft function but does not affect 1-year graft function.
Journal of the American Society of Nephrology : JASN 20040101
-
Stent fracture and restenosis in the drug-eluting stent era.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040101
-
Rapamycin attenuates atherosclerosis induced by dietary cholesterol in apolipoprotein-deficient mice through a p27 Kip1 -independent pathway.
Atherosclerosis 20040101
-
Health-related quality of life outcomes after kidney transplantation.
Health and quality of life outcomes 20040101
-
Sirolimus-eluting stents inhibit neointimal hyperplasia in diabetic patients. Insights from the RAVEL Trial.
European heart journal 20040101
-
Drug immunosuppression therapy for adult heart transplantation. Part 1: immune response to allograft and mechanism of action of immunosuppressants.
The Annals of thoracic surgery 20040101
-
Antitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells.
Cancer research 20040101
-
Rapamycin inhibits the growth and metastatic progression of non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 20040101
-
Clinical pharmacokinetics of everolimus.
Clinical pharmacokinetics 20040101
-
[Prevention of in-stent restenosis: towards an in situ treatment?].
Medecine sciences : M/S 20040101
-
Update on sirolimus drug-eluting stents.
Current pharmaceutical design 20040101
-
Arsenite induces p70S6K1 activation and HIF-1alpha expression in prostate cancer cells.
Molecular and cellular biochemistry 20040101
-
The management of immunosuppression: the art and the science.
Critical care nursing quarterly 20040101
-
Transforming growth factor-beta induces Cdk2 relocalization to the cytoplasm coincident with dephosphorylation of retinoblastoma tumor suppressor protein.
Breast cancer research : BCR 20040101
-
Everolimus/cyclosporine interactions on bile flow and biliary excretion of bile salts and cholesterol in rats.
Digestive diseases and sciences 20040101
-
Sirolimus: a ten-year perspective.
Transplantation proceedings 20040101
-
Adverse events and Cypher stents.
FDA consumer 20040101
-
Immunophilin ligands decrease release of pro-inflammatory cytokines (IL-1beta, TNF-alpha and IL-2 in rat astrocyte cultures exposed to simulated ischemia in vitro.
Polish journal of pharmacology 20040101
-
Everolimus.
Drugs 20040101
-
Translation of the radioresistance kinase TLK1B is induced by gamma-irradiation through activation of mTOR and phosphorylation of 4E-BP1.
BMC molecular biology 20040101
-
Lessons from the E-SIRIUS trial.
Italian heart journal : official journal of the Italian Federation of Cardiology 20040101
-
Sirolimus-eluting coronary stents: novel devices for the management of coronary artery disease.
American journal of therapeutics 20040101
-
Signaling of angiotensin II-induced vascular protein synthesis in conduit and resistance arteries in vivo.
BMC cardiovascular disorders 20040101
-
New immunosuppressive strategies in renal transplant recipients.
Journal of nephrology 20040101
-
Overcoming endocrine therapy resistance by signal transduction inhibition.
The oncologist 20040101
-
Everolimus for stent-based intracoronary applications.
Reviews in cardiovascular medicine 20040101
-
Liposomal formulations of tacrolimus and rapamycin increase graft survival and fiber outgrowth of dopaminergic grafts.
Cell transplantation 20040101
-
Update on transplant pharmacology: sirolimus.
Dimensions of critical care nursing : DCCN 20040101
-
[Stents without restenosis--true or a myth?].
Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti 20040101
-
Conversion to sirolimus-based maintenance immunosuppression using daclizumab bridge therapy in renal transplant recipients.
Clinical transplantation 20040101
-
Augmentation of T-cell apoptosis by immunosuppressive agents.
Clinical transplantation 20040101
-
[De novo hemolytic uremic syndrome in a kidney-pancreas recipient in the postoperative period].
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101
-
[Interstitial pneumonitis associated with sirolimus administration in a renal transplantation patient: a clinical case].
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101
-
[Calcineurin-inhibitor-free immunosuppression in early renal transplantation].
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101
-
[Everolimus: immunosuppression with antilymphoproliferative therapy].
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101
-
Functional analysis of APC-Cdh1.
Methods in molecular biology (Clifton, N.J.) 20040101
-
[Italian Consensus Conference on drug-eluting stents].
Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20040101
-
Induction sirolimus and delayed graft function after deceased donor kidney transplantation in the United States.
American journal of nephrology 20040101
-
Low-dose sirolimus in combination with mycophenolate mofetil improves kidney graft function late after renal transplantation and suggests pharmacokinetic interaction of both immunosuppressive drugs.
Kidney & blood pressure research 20040101
-
Sirolimus dosage during and after conversion from calcineurin inhibitor therapy to sirolimus in chronic kidney transplant patients.
Kidney & blood pressure research 20040101
-
New targets for therapy in breast cancer: mammalian target of rapamycin (mTOR) antagonists.
Breast cancer research : BCR 20040101
-
[Vascular and interventional radiology].
Journal de radiologie 20040101
-
Effect of rapamycin on cytokine profile in kidney transplant recipients treated with triple drug therapy.
Transplantation proceedings 20040101
-
Donor stem cell infusion after non-myeloablative conditioning for tolerance induction to HLA mismatched adult living-donor liver graft.
Transplant immunology 20040101
-
Immune status assay (ISA): a noninvasive procedure for studying allograft rejection.
Transplant immunology 20040101
-
Method development for the quantitation of ABT-578 in rabbit artery tissue by 96-well liquid-liquid extraction and liquid chromatography/tandem mass spectrometric detection.
Rapid communications in mass spectrometry : RCM 20040101
-
Empirical assessment of the impact of drug-eluting stents on the rate of use of coronary revascularization procedures.
International journal of technology assessment in health care 20040101
-
Addition of heparin to contrast media is associated with increased bleeding and peripheral vascular complications during percutaneous coronary intervention with bivalirudin and drug-eluting stents.
Cardiovascular radiation medicine 20040101
-
Molecular targeting: PI3 kinase pathway.
Annals of oncology : official journal of the European Society for Medical Oncology 20040101
-
Pamidronate resistance and associated low ras levels in breast cancer cells: a role for combinatorial therapy.
Annals of clinical and laboratory science 20040101
-
[First experience of the use of sirolimus covered stents output in the treatment of ischemic heart disease].
Kardiologiia 20040101
-
Asymptomatic late stent thrombosis after sirolimus stent implantation.
Cardiovascular radiation medicine 20040101
-
Rapamycin inhibits Akt-mediated oncogenic transformation and tumor growth.
Anticancer research 20040101
-
Drug-coated stents: preventing restenosis in coronary artery disease.
The Journal of cardiovascular nursing 20040101
-
[Restenosis inside the stent: treatment and prevention].
Klinicheskaia meditsina 20040101
-
Temsirolimus: CCI 779, CCI-779, cell cycle inhibitor-779.
Drugs in R&D 20040101
-
Immunomodulatory therapy in ophthalmology - is there a place for topical application?
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20040101
-
Therapeutic monitoring of immunosuppressant drugs. Where are we?
Clinical chemistry and laboratory medicine 20040101
-
The pleiotropic effects of mTor inhibitors.
Journal of nephrology 20040101
-
Sirolimus-based immunosuppression: present state of the art.
Journal of nephrology 20040101
-
From balloon angioplasty to drug-eluting stents: revolution or evolution?
The American heart hospital journal 20040101
-
Drug-eluting stents: are they really safe?
The American heart hospital journal 20040101
-
Differential effects of rapamycin, cyclosporine A, and FK506 on human coronary artery smooth muscle cell proliferation and signalling.
Vascular pharmacology 20040101
-
Sirolimus therapy in orthotopic liver transplant (OLT) recipients with acute renal insufficiency.
Digestive diseases and sciences 20040101
-
[Cancer after kidney transplantation].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20040101
-
An evidence-based approach to the use of drug-eluting stents in clinical practice.
The American heart hospital journal 20040101
-
Late thrombosis in cypher stents after the discontinuation of antiplatelet therapy.
Cardiovascular radiation medicine 20040101
-
CNI-sparing regimens within the liver transplant setting: experiences of a single center.
Clinical transplants 20040101
-
The impact of sirolimus, mycophenolate mofetil, cyclosporine, azathioprine, and steroids on wound healing in 513 kidney-transplant recipients.
Transplantation 20031227
-
Sirolimus inhibits oxidative burst activity in transplant recipients.
Transplantation 20031227
-
Sirolimus myopathy.
Transplantation 20031227
-
Rapamycin induces the fusion-type independent downregulation of the EWS/FLI-1 proteins and inhibits Ewing's sarcoma cell proliferation.
Oncogene 20031218
-
Blocking the monocyte chemoattractant protein-1/CCR2 chemokine pathway induces permanent survival of islet allografts through a programmed death-1 ligand-1-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 20031215
-
Sirolimus delays recovery of rat kidney transplants after ischemia-reperfusion injury.
Transplantation 20031215
-
Elevated portal vein drug levels of sirolimus and tacrolimus in islet transplant recipients: local immunosuppression or islet toxicity?
Transplantation 20031215
-
Sirolimus-atorvastatin drug interaction in the pancreatic islet transplant recipient.
Transplantation 20031215
-
Everolimus in cardiac-transplant recipients.
The New England journal of medicine 20031204
-
Long-term follow-up of incomplete stent apposition in patients who received sirolimus-eluting stent for de novo coronary lesions: an intravascular ultrasound analysis.
Circulation 20031202
-
Insulin-dependent signaling regulates azurophil granule-selective macroautophagy in human myeloblastic cells.
Journal of leukocyte biology 20031201
-
Long-term treatment with insulin induces apoptosis in brown adipocytes: role of oxidative stress.
Endocrinology 20031201
-
Ortho-substituted PCBs kill thymocytes.
Toxicological sciences : an official journal of the Society of Toxicology 20031201
-
New therapeutic strategies for soft tissue sarcomas.
Current treatment options in oncology 20031201
-
Homodirectional changes in transcriptome composition and mRNA translation induced by rapamycin and heat shock.
Nature structural biology 20031201
-
Pharmacologic prevention of both restenosis and atherosclerosis progression: AGI-1067, probucol, statins, folic acid and other therapies.
Current opinion in lipidology 20031201
-
Restenosis due to underexpansion of sirolimus-eluting stent in a bifurcation lesion.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20031201
-
Late stent thrombosis after implantation of a sirolimus-eluting stent.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20031201
-
The porcine coronary model of in-stent restenosis: current status in the era of drug-eluting stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20031201
-
Influence of delayed initiation of cyclosporine on everolimus pharmacokinetics in de novo renal transplant patients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20031201
-
Antiproliferative coatings for the treatment of coronary heart disease:. what are the targets and which are the tools?
Journal of interventional cardiology 20031201
-
Treatment of bifurcation coronary lesions: a review of current techniques and outcome.
Journal of interventional cardiology 20031201
-
Benefits and risks of solitary islet transplantation for type 1 diabetes using steroid-sparing immunosuppression: the National Institutes of Health experience.
Diabetes care 20031201
-
Usefulness of shear stress pattern in predicting neointima distribution in sirolimus-eluting stents in coronary arteries.
The American journal of cardiology 20031201
-
Assessment of immunosuppressive drug interactions: inhibition of lymphocyte function in peripheral human blood.
Journal of immunological methods 20031201
-
Differential effects of rapamycin on mammalian target of rapamycin signaling functions in mammalian cells.
Cancer research 20031201
-
Rapamycin has no effect on fibrosis-associated gene expression or extracellular matrix accumulation when administered to animals with established or early allograft vasculopathy.
The Journal of thoracic and cardiovascular surgery 20031201
-
TOR and PKA signaling pathways converge on the protein kinase Rim15 to control entry into G0.
Molecular cell 20031201
-
Conditional protein alleles using knockin mice and a chemical inducer of dimerization.
Molecular cell 20031201
-
Sirolimus therapy in orthotopic liver transplant recipients with calcineurin inhibitor related chronic renal insufficiency.
Transplantation proceedings 20031201
-
Effect of sirolimus on the cholesterol content of aortic arch in ApoE knockout mice.
Transplantation proceedings 20031201
-
Regulating cell surface glycosylation by small molecule control of enzyme localization.
Chemistry & biology 20031201
-
[Immunomodulation in penetrating keratoplasty. Current status and perspectives].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20031201
-
Current immunosuppressive agents: efficacy, side effects, and utilization.
Pediatric clinics of North America 20031201
-
The arsenal. The latest in drugs, surgery, and devices.
U.S. news & world report 20031201
-
Sirolimus add-on rescue therapy can benefit patients with chronic renal allograft dysfunction.
Journal of the Formosan Medical Association = Taiwan yi zhi 20031201
-
Angioplasty: no more repeats.
The Johns Hopkins medical letter health after 50 20031201
-
Low incidence of cytomegalovirus disease in liver transplant recipients receiving sirolimus primary immunosuppression with 3-day corticosteroid taper.
Transplant infectious disease : an official journal of the Transplantation Society 20031201
-
Ser-64 and Ser-111 in PHAS-I are dispensable for insulin-stimulated dissociation from eIF4E.
The Journal of biological chemistry 20031128
-
[Are drug-coated stents too expensive?].
Deutsche medizinische Wochenschrift (1946) 20031121
-
Atrophic remodeling of the heart in vivo simultaneously activates pathways of protein synthesis and degradation.
Circulation 20031118
-
Chromatin-mediated regulation of nucleolar structure and RNA Pol I localization by TOR.
The EMBO journal 20031117
-
Immediate response of mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in rat skeletal muscle.
The Journal of physiology 20031115
-
Control of nutrient-sensitive transcription programs by the unconventional prefoldin URI.
Science (New York, N.Y.) 20031114
-
Akt promotes increased mammalian cell size by stimulating protein synthesis and inhibiting protein degradation.
American journal of physiology. Endocrinology and metabolism 20031101
-
Characterization of the transport of the bicyclic peptide phalloidin by human hepatic transport proteins.
Naunyn-Schmiedeberg's archives of pharmacology 20031101
-
Rapamycin antagonizes cyclosporin A- and tacrolimus (FK506)-mediated augmentation of linker for activation of T cell expression in T cells.
International immunology 20031101
-
Sirolimus-induced interstitial pneumonitis in an islet transplant recipient.
Diabetes care 20031101
-
Rapamycin has a deleterious effect on MIN-6 cells and rat and human islets.
Diabetes 20031101
-
Macrophage colony-stimulating factor-dependent macrophage proliferation is mediated through a calcineurin-independent but immunophilin-dependent mechanism that mediates the activation of external regulated kinases.
European journal of immunology 20031101
-
Design and structure-based study of new potential FKBP12 inhibitors.
Biophysical journal 20031101
-
Angiographic regression of cardiac allograft vasculopathy after introducing sirolimus immunosuppression.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20031101
-
Multi-lesion culotte and crush bifurcation stenting with sirolimus-eluting stents: long-term angiographic outcome.
The Journal of invasive cardiology 20031101
-
Low-dose sirolimus in combination with mycophenolate in calcineurin inhibitor elimination: the Kuwaiti experience.
Transplantation proceedings 20031101
-
Induction of protein synthesis in cardiac fibroblasts by cardiotrophin-1: integration of multiple signaling pathways.
Cardiovascular research 20031101
-
The role of nitrate reductase in the regulation of the nitrate assimilation pathway in the yeast Hansenula polymorpha.
FEMS yeast research 20031101
-
Determination of the pharmacokinetics of cerivastatin when administered in combination with sirolimus and cyclosporin A in patients with kidney transplant, and review of the relevant literature.
International journal of clinical pharmacology and therapeutics 20031101
-
Drug-eluting stents in peripheral vascular disease: eliminating restenosis.
The Mount Sinai journal of medicine, New York 20031101
-
Will mTOR inhibitors make it as cancer drugs?
Cancer cell 20031101
-
Immunosuppression in renal transplantation: where are we now?
Hospital medicine (London, England : 1998) 20031101
-
Bibliography. Current world literature. Therapeutic modalities.
Current opinion in oncology 20031101
-
Differential effect of cyclosporine A and SDZ RAD on neointima formation of carotid allografts in apolipoprotein E-deficient mice.
Transplantation 20031027
-
Sirolimus-eluting stent implantation in ST-elevation acute myocardial infarction: a clinical and angiographic study.
Circulation 20031021
-
Target of rapamycin (TOR)-signaling and RAIP motifs play distinct roles in the mammalian TOR-dependent phosphorylation of initiation factor 4E-binding protein 1.
The Journal of biological chemistry 20031017
-
Drug-eluting stents substantially lower rate of restenosis.
Report on medical guidelines & outcomes research 20031017
-
Insulin independence after conversion to tacrolimus and sirolimus-based immunosuppression in islet-kidney recipients.
Transplantation 20031015
-
Involvement of the VDE homing endonuclease and rapamycin in regulation of the Saccharomyces cerevisiae GSH11 gene encoding the high affinity glutathione transporter.
The Journal of biological chemistry 20031010
-
Drug-delivering coronary artery stents: bare metal threatened by extinction?
Lancet (London, England) 20031004
-
Sirolimus-eluting stents for treatment of patients with long atherosclerotic lesions in small coronary arteries: double-blind, randomised controlled trial (E-SIRIUS).
Lancet (London, England) 20031004
-
Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2.
The Journal of biological chemistry 20031003
-
Sirolimus for the prevention of in-stent restenosis in a coronary artery.
The New England journal of medicine 20031002
-
Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery.
The New England journal of medicine 20031002
-
Beta-adrenergic agonists regulate Na-K-ATPase via p70S6k.
American journal of physiology. Lung cellular and molecular physiology 20031001
-
Amino acid transport regulates blastocyst implantation.
Biology of reproduction 20031001
-
Rapamycin-based rescue therapy after chronic rejection in a pediatric liver transplant patient.
Transplant international : official journal of the European Society for Organ Transplantation 20031001
-
Tissue-specific regulation of protein synthesis by insulin and free fatty acids.
American journal of physiology. Endocrinology and metabolism 20031001
-
Cytokines regulate the pattern of rejection and susceptibility to cyclosporine therapy in different mouse recipient strains after cardiac allografting.
Journal of immunology (Baltimore, Md. : 1950) 20031001
-
M-CSF, TNFalpha and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase.
Cell death and differentiation 20031001
-
Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade.
Nature medicine 20031001
-
Determination of sirolimus blood concentration using high-performance liquid chromatography with ultraviolet detection.
Therapeutic drug monitoring 20031001
-
Pharmacokinetic interactions between sirolimus and microemulsion cyclosporine when orally administered jointly and 4 hours apart in healthy volunteers.
Journal of clinical pharmacology 20031001
-
Pilot study of oral rapamycin to prevent restenosis in patients undergoing coronary stent therapy: Argentina Single-Center Study (ORAR Trial).
The Journal of invasive cardiology 20031001
-
[Non cardiac surgery in patient with coronary stenting: think sirolimus now!].
Annales francaises d'anesthesie et de reanimation 20031001
-
Renal function improves in liver transplant recipients when switched from a calcineurin inhibitor to sirolimus.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20031001
-
Negative regulation of interleukin-12 production by a rapamycin-sensitive signaling pathway: a brief communication.
Experimental biology and medicine (Maywood, N.J.) 20031001
-
Rapamycin preserves renal function compared with cyclosporine A after ischemia/reperfusion injury.
Urology 20031001
-
Everolimus in de novo cardiac transplantation: pharmacokinetics, therapeutic range, and influence on cyclosporine exposure.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20031001
-
Sirolimus-eluting stents for the treatment of in-stent restenosis.
Minerva cardioangiologica 20031001
-
Evolving standard in the treatment of coronary artery disease. Drug-eluting stents.
Minerva cardioangiologica 20031001
-
Using intravascular ultrasound with drug-eluting stents. What have we learned so far?
Minerva cardioangiologica 20031001
-
Attachment of the ubiquitin-related protein Urm1p to the antioxidant protein Ahp1p.
Eukaryotic cell 20031001
-
Excellent short-term results with steroid-free maintenance immunosuppression in low-risk simultaneous pancreas-kidney transplantation.
Archives of surgery (Chicago, Ill. : 1960) 20031001
-
The PCPH oncoprotein antagonizes the proapoptotic role of the mammalian target of rapamycin in the response of normal fibroblasts to ionizing radiation.
Cancer research 20031001
-
Drug-eluting stents and glycoprotein IIb/IIIa inhibitors: combination therapy for the future.
American heart journal 20031001
-
Posterior leukoencephalopathy with cyclosporine.
Clinical nephrology 20031001
-
Immunosuppression in liver transplantation.
Minerva chirurgica 20031001
-
[Perspectives of pharmacological anti-proliferative therapy for arteriosclerosis].
Recenti progressi in medicina 20031001
-
Drug-eluting versus bare metal coronary stents: long-term human pathology. Findings from different coronary arteries in the same patient.
Italian heart journal : official journal of the Italian Federation of Cardiology 20031001
-
Withdrawal of steroid therapy in African American kidney transplant recipients receiving sirolimus and tacrolimus.
Transplantation 20030927
-
Tor1/2 regulation of retrograde gene expression in Saccharomyces cerevisiae derives indirectly as a consequence of alterations in ammonia metabolism.
The Journal of biological chemistry 20030919
-
Anti-third-party veto CTLs overcome rejection of hematopoietic allografts: synergism with rapamycin and BM cell dose.
Blood 20030915
-
Rapamycin-induced oligospermia.
Transplantation 20030915
-
Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin.
Cancer research 20030915
-
Mitogenic effect of glial cell line-derived neurotrophic factor is dependent on the activation of p70S6 kinase, but independent of the activation of ERK and up-regulation of Ret in SH-SY5Y cells.
Brain research 20030905
-
Conditional protein splicing: a new tool to control protein structure and function in vitro and in vivo.
Journal of the American Chemical Society 20030903
-
Rapamycin causes down-regulation of CCR5 and accumulation of anti-HIV beta-chemokines: an approach to suppress R5 strains of HIV-1.
Proceedings of the National Academy of Sciences of the United States of America 20030902
-
Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation.
Blood 20030901
-
Drosophila Rheb GTPase is required for cell cycle progression and cell growth.
Journal of cell science 20030901
-
Comparison of sirolimus vs. mycophenolate mofetil on surgical complications and wound healing in adult kidney transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030901
-
Oral rapamycin in the treatment of diffuse proliferative in-stent restenosis in a patient with small reference vessel.
The Journal of invasive cardiology 20030901
-
Involvement of the Akt/mTOR pathway on EGF-induced cell transformation.
Molecular carcinogenesis 20030901
-
The long-term survival of baboon-to-monkey kidney and liver xenografts.
Xenotransplantation 20030901
-
Parallel purification of three catalytic subunits of the protein serine/threonine phosphatase 2A family (PP2A(C), PP4(C), and PP6(C)) and analysis of the interaction of PP2A(C) with alpha4 protein.
Protein expression and purification 20030901
-
Second window of protection following myocardial preconditioning: an essential role for PI3 kinase and p70S6 kinase.
Journal of molecular and cellular cardiology 20030901
-
Rapamycin treatment at immunosuppressive doses affects tumor blood vessel circulation.
Transplantation proceedings 20030901
-
Rapamycin in children after liver transplantation.
Transplantation proceedings 20030901
-
Pathologic assessment of cardiomyocytes in heart transplant recipients treated with rapamycin or cyclosporine.
Transplantation proceedings 20030901
-
Deterioration of renal function after replacement of cyclosporine with sirolimus in five patients with severe renal impairment late after heart transplantation.
Transplantation proceedings 20030901
-
Restenosis in percutaneous coronary intervention--is drug-eluting stent the answer?
Singapore medical journal 20030901
-
Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner.
The Journal of biological chemistry 20030829
-
Rapamycin inhibits GM-CSF-induced neutrophil migration.
FEBS letters 20030828
-
Cardiac-allograft vasculopathy.
The New England journal of medicine 20030828
-
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
The New England journal of medicine 20030828
-
LF 15-0195, a novel immunosuppressive agent prevents rejection and induces operational tolerance in a mouse cardiac allograft model.
Transplantation 20030827
-
Muscarinic receptor-mediated activation of p70 S6 kinase 1 (S6K1) in 1321N1 astrocytoma cells: permissive role of phosphoinositide 3-kinase.
The Biochemical journal 20030815
-
Synergistic effects of CTLA-4Ig and sirolimus on orthotopic lung-allograft survival and histology.
Transplantation 20030815
-
Apoptosis and treatment of chronic allograft nephropathy with everolimus.
Transplantation 20030815
-
Successful infliximab treatment of steroid and OKT3 refractory acute cellular rejection in two patients after intestinal transplantation.
Transplantation 20030815
-
Chronic myeloid leukemia: pathophysiology, diagnostic parameters, and current treatment concepts.
Wiener klinische Wochenschrift 20030814
-
CYPHER coronary stents and risk of thrombosis.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20030805
-
Survival of acute myeloid leukemia cells requires PI3 kinase activation.
Blood 20030801
-
Intestinal sugar absorption is regulated by phosphorylation and turnover of protein kinase C betaII mediated by phosphatidylinositol 3-kinase- and mammalian target of rapamycin-dependent pathways.
The Journal of biological chemistry 20030801
-
Divergence in signaling pathways involved in promotion of cell viability mediated by bFGF, NGF, and EGF in PC12 cells.
Neurochemical research 20030801
-
The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor.
Genes & development 20030801
-
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling.
Genes & development 20030801
-
The phosphatidylinositol-3 kinase (PI3K)-Akt pathway suppresses neurite branch formation in NGF-treated PC12 cells.
Genes to cells : devoted to molecular & cellular mechanisms 20030801
-
Long-term pharmacokinetic study of the novel combination of tacrolimus and sirolimus in de novo renal allograft recipients.
Therapeutic drug monitoring 20030801
-
Effectiveness of sirolimus-eluting stent for treatment of left main coronary artery disease.
The American journal of cardiology 20030801
-
Effects of FK506 and rapamycin on generation of reactive oxygen species, nitric oxide production and nuclear factor kappa B activation in rat hepatocytes.
Biochemical pharmacology 20030801
-
Rapamycin inhibits the interleukin 10 signal transduction pathway and the growth of Epstein Barr virus B-cell lymphomas.
Cancer research 20030801
-
Immunophilins, mTOR, and pharmacodynamic strategies for a targeted cancer therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 20030801
-
Pharmacodynamic Evaluation of CCI-779, an Inhibitor of mTOR, in Cancer Patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 20030801
-
Rapamycin-sensitive signalling in long-term consolidation of auditory cortex-dependent memory.
The European journal of neuroscience 20030801
-
Postgrafting immunosuppression with sirolimus and cyclosporine facilitates stable mixed hematopoietic chimerism in dogs given sublethal total body irradiation before marrow transplantation from DLA-identical littermates.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20030801
-
Rapamycin inhibits telomerase activity by decreasing the hTERT mRNA level in endometrial cancer cells.
Molecular cancer therapeutics 20030801
-
Treatment of idiopathic nephrosis by immunophillin modulation.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030801
-
TSC2 regulates VEGF through mTOR-dependent and -independent pathways.
Cancer cell 20030801
-
Early elimination of cyclosporine in kidney transplant recipients receiving sirolimus prevents progression of chronic pathologic allograft lesions.
Transplantation proceedings 20030801
-
Defining the initial doses of sirolimus and tacrolimus in the period immediately after renal transplantation.
Transplantation proceedings 20030801
-
Rapamycin in lung transplantation: preliminary results.
Transplantation proceedings 20030801
-
Sirolimus in heart transplantation: a single center initial experience.
Transplantation proceedings 20030801
-
Integration of growth factor and nutrient signaling: implications for cancer biology.
Molecular cell 20030801
-
Retrograde signaling is regulated by the dynamic interaction between Rtg2p and Mks1p.
Molecular cell 20030801
-
Sirolimus-induced interstitial pneumonitis in a renal transplant recipient.
Journal of the Formosan Medical Association = Taiwan yi zhi 20030801
-
Sirolimus does not increase the risk for postoperative thromboembolic events among renal transplant recipients.
Transplantation 20030727
-
Long-term improvement in renal function with sirolimus after early cyclosporine withdrawal in renal transplant recipients: 2-year results of the Rapamune Maintenance Regimen Study.
Transplantation 20030727
-
Dyslipidemia in renal transplant recipients treated with a sirolimus and cyclosporine-based immunosuppressive regimen: incidence, risk factors, progression, and prognosis.
Transplantation 20030727
-
Higher surgical wound complication rates with sirolimus immunosuppression after kidney transplantation: a matched-pair pilot study.
Transplantation 20030727
-
Mechanism of ribosomal p70S6 kinase activation by granulocyte macrophage colony-stimulating factor in neutrophils: cooperation of a MEK-related, THR421/SER424 kinase and a rapamycin-sensitive, m-TOR-related THR389 kinase.
The Journal of biological chemistry 20030725
-
Coronary restenosis after sirolimus-eluting stent implantation: morphological description and mechanistic analysis from a consecutive series of cases.
Circulation 20030722
-
Restenosis: the mouse that roared.
Circulation 20030722
-
Modulation of translation-initiation in CHO-K1 cells by rapamycin-induced heterodimerization of engineered eIF4G fusion proteins.
Biotechnology and bioengineering 20030720
-
Hyperosmotic stress inhibits insulin receptor substrate-1 function by distinct mechanisms in 3T3-L1 adipocytes.
The Journal of biological chemistry 20030718
-
Mutational analysis of ribosomal S6 kinase 2 shows differential regulation of its kinase activity from that of ribosomal S6 kinase 1.
The Biochemical journal 20030715
-
Ca(2+)-independent protein kinase C activity is required for alpha1-adrenergic-receptor-mediated regulation of ribosomal protein S6 kinases in adult cardiomyocytes.
The Biochemical journal 20030715
-
Effectiveness of sirolimus-eluting stent implantation for recurrent in-stent restenosis after brachytherapy.
The American journal of cardiology 20030715
-
Rabbit antithymocyte globulin induction and sirolimus monotherapy supports prolonged islet allograft function in a nonhuman primate islet transplantation model.
Transplantation 20030715
-
Novel sulfur-containing rapamycin analogs prepared by precursor-directed biosynthesis.
Organic letters 20030710
-
Differential translation of TOP mRNAs in rapamycin-treated human B lymphocytes.
Biochimica et biophysica acta 20030709
-
Use of rapamycin slows progression of cardiac transplantation vasculopathy.
Circulation 20030708
-
Rapamycin for cardiac transplant rejection and vasculopathy: one stone, two birds?
Circulation 20030708
-
Rapamycin slows heart transplant vasculopathy.
Circulation 20030708
-
Alpha-Synuclein is degraded by both autophagy and the proteasome.
The Journal of biological chemistry 20030704
-
Sirolimus and mycophenolate mofetil after liver transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 20030701
-
Effects of cyclosporin A and a rapamycin derivative (SAR943) on chronic allergic inflammation in sensitized rats.
Immunology 20030701
-
The role of c-Myc on granulocyte colony-stimulating factor-dependent neutrophilic proliferation and differentiation of HL-60 cells.
Biochemical pharmacology 20030701
-
Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways.
The American journal of pathology 20030701
-
Interstitial granulomatous pneumonitis associated with sirolimus in a child after liver transplantation.
Journal of pediatric gastroenterology and nutrition 20030701
-
Effects of immunomodulators on airways hyperresponsiveness to adenosine induced in actively sensitised Brown Norway rats by exposure to allergen.
Naunyn-Schmiedeberg's archives of pharmacology 20030701
-
Sirolimus-induced thrombotic microangiopathy in a renal transplant recipient.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20030701
-
The influence of the rapamycin-derivate SDZ RAD on the healing of airway anastomoses.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20030701
-
'Cyclosporine-sparing' regimen approved.
The American journal of nursing 20030701
-
[Position paper on the use of drug eluting stents (DES) in percutaneous coronary interventions in patients with coronary heart disease].
Zeitschrift fur Kardiologie 20030701
-
Mutant type glutathione S-transferase theta 1 gene homologue to mTOR in myelodysplastic syndrome: possible clinical application of rapamycin.
Leukemia & lymphoma 20030701
-
New stents, hopes--and questions. After approval of a drug-coated cylinder, patients face wider options.
Heart advisor 20030701
-
High-throughput liquid chromatography-tandem mass spectrometric analysis of sirolimus in whole blood.
Clinical chemistry and laboratory medicine 20030701
-
mTOR inhibitors in hematologic malignancies.
Clinical advances in hematology & oncology : H&O 20030701
-
A prospective randomized multicenter study of tacrolimus in combination with sirolimus in renal-transplant recipients.
Transplantation 20030627
-
Everolimus in pediatric de nova renal transplant patients.
Transplantation 20030627
-
Treatment with humanized monoclonal antibodies against CD80 and CD86 combined with sirolimus prolongs renal allograft survival in cynomolgus monkeys.
Transplantation 20030627
-
Primary intestinal posttransplant T-cell lymphoma.
Transplantation 20030627
-
Phospholipase D confers rapamycin resistance in human breast cancer cells.
Oncogene 20030619
-
Induction of apoptosis in IL-3-dependent hematopoietic cell lines by guanine nucleotide depletion.
Blood 20030615
-
Proliferation and survival of activated B cells requires sustained antigen receptor engagement and phosphoinositide 3-kinase activation.
Journal of immunology (Baltimore, Md. : 1950) 20030615
-
Pharmacologically regulated production of targeted retrovirus from T cells for systemic antitumor gene therapy.
Cancer research 20030615
-
Long-term islet allograft survival in nonobese diabetic mice treated with tacrolimus, rapamycin, and anti-interleukin-2 antibody.
Transplantation 20030615
-
First drug-eluting coronary stent approved.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20030615
-
Regulation of the phosphatidylinositol 3-kinase, Akt/protein kinase B, FRAP/mammalian target of rapamycin, and ribosomal S6 kinase 1 signaling pathways by thyroid-stimulating hormone (TSH) and stimulating type TSH receptor antibodies in the thyroid gland.
The Journal of biological chemistry 20030613
-
Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2 alpha kinase GCN2.
The Journal of biological chemistry 20030606
-
Early outcome after sirolimus-eluting stent implantation in patients with acute coronary syndromes: insights from the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) registry.
Journal of the American College of Cardiology 20030604
-
Rapamycin inhibits IL-4--induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo.
Blood 20030601
-
Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability.
The Biochemical journal 20030601
-
p38 MAP kinase regulates BMP-4-stimulated VEGF synthesis via p70 S6 kinase in osteoblasts.
American journal of physiology. Endocrinology and metabolism 20030601
-
Campath-1H induction plus rapamycin monotherapy for renal transplantation: results of a pilot study.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030601
-
Influence of SDZ RAD vs. MMF on gastric emptying in renal transplant recipients.
Clinical transplantation 20030601
-
Single HSV-amplicon vector mediates drug-induced gene expression via dimerizer system.
Molecular therapy : the journal of the American Society of Gene Therapy 20030601
-
The evolving role of sirolimus in renal transplantation.
QJM : monthly journal of the Association of Physicians 20030601
-
Phase I and pharmacokinetic study of CCI-779, a novel cytostatic cell-cycle inhibitor, in combination with 5-fluorouracil and leucovorin in patients with advanced solid tumors.
Annals of oncology : official journal of the European Society for Medical Oncology 20030601
-
Rapamycin treatment results in GATA factor-independent hyperphosphorylation of the proline utilization pathway activator in Saccharomyces cerevisiae.
Eukaryotic cell 20030601
-
Vanadate and rapamycin synergistically enhance insulin-stimulated glucose uptake.
Metabolism: clinical and experimental 20030601
-
Multiple roles of Tap42 in mediating rapamycin-induced transcriptional changes in yeast.
Molecular cell 20030601
-
Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21(Cip1).
Molecular cell 20030601
-
The rush is on to acquire drug-eluting stents.
Hospital material[dollar sign] management 20030601
-
Rapid conversion to sirolimus for chronic progressive deterioration of the renal function in kidney allograft recipients.
Transplantation proceedings 20030601
-
Opening the shut cases. Drug-coated stents may solve the biggest problem with angioplasty--keeping coronary arteries open.
Harvard health letter 20030601
-
In vitro immunomodulatory activity of ruthenium complexes.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030601
-
Mammalian target of rapamycin: a new molecular target for breast cancer.
Clinical breast cancer 20030601
-
[Drug-eluting stents in complex lesions].
Annales de cardiologie et d'angeiologie 20030601
-
[In-stent restenosis: which indications for drug-eluting stent?].
Annales de cardiologie et d'angeiologie 20030601
-
Sirolimus: a current perspective.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20030601
-
Immunosuppressive TOR kinase inhibitor everolimus (RAD) suppresses growth of cells derived from posttransplant lymphoproliferative disorder at allograft-protecting doses.
Transplantation 20030527
-
Synergistic immunosuppressive effects of rosmarinic acid and rapamycin in vitro and in vivo.
Transplantation 20030527
-
ERK and p38 inhibit the expression of 4E-BP1 repressor of translation through induction of Egr-1.
The Journal of biological chemistry 20030523
-
Insulin induces expression of adenosine kinase gene in rat lymphocytes by signaling through the mitogen-activated protein kinase pathway.
Experimental cell research 20030515
-
Airway anastomotic dehiscence associated with use of sirolimus immediately after lung transplantation.
Transplantation 20030515
-
Superior T-cell suppression by rapamycin and FK506 over rapamycin and cyclosporine A because of abrogated cytotoxic T-lymphocyte induction, impaired memory responses, and persistent apoptosis.
Transplantation 20030515
-
Sirolimus (rapamycin) monotherapy prevents graft vascular disease in nonhuman primate recipients of orthotopic aortic allografts.
Circulation 20030513
-
Domains of Gln3p interacting with karyopherins, Ure2p, and the target of rapamycin protein.
The Journal of biological chemistry 20030509
-
Preliminary observations regarding angiographic pattern of restenosis after rapamycin-eluting stent implantation.
Circulation 20030506
-
Critical role for PI 3-kinase in the control of erythropoietin-induced erythroid progenitor proliferation.
Blood 20030501
-
Estradiol rapidly activates Akt via the ErbB2 signaling pathway.
Molecular endocrinology (Baltimore, Md.) 20030501
-
Involvement of S6 kinase and p38 mitogen activated protein kinase pathways in strain-induced alignment and proliferation of bovine aortic smooth muscle cells.
Journal of cellular physiology 20030501
-
Transplant immunosuppressant agents and their role in autoimmune rheumatic diseases.
Current opinion in rheumatology 20030501
-
Evaluation of coronary remodeling after sirolimus-eluting stent implantation by serial three-dimensional intravascular ultrasound.
The American journal of cardiology 20030501
-
Pharmacokinetics of tacrolimus-based combination therapies.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030501
-
Sirolimus as primary immunosuppression in liver transplantation is not associated with hepatic artery or wound complications.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20030501
-
Rapamycin: friend, foe, or misunderstood?
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20030501
-
A retrospective review of sirolimus (Rapamune) therapy in orthotopic liver transplant recipients diagnosed with chronic rejection.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20030501
-
TOR inhibitors and cardiac allograft vasculopathy: is inhibition of intimal thickening an adequate surrogate of benefit?
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030501
-
Rapamycin inhibits vascular remodeling in an experimental model of allograft vasculopathy and attenuates associated changes in fibrosis-associated gene expression.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030501
-
Sirolimus: its discovery, biological properties, and mechanism of action.
Transplantation proceedings 20030501
-
The development of immunosuppression: the rapamycin milestone.
Transplantation proceedings 20030501
-
The Rapamune era of immunosuppression 2003: the journey from the laboratory to clinical transplantation.
Transplantation proceedings 20030501
-
Ten years of sirolimus therapy for human renal transplantation: the University of Texas at Houston experience.
Transplantation proceedings 20030501
-
Sirolimus therapy without calcineurin inhibitors: Necker Hospital 8-year experience.
Transplantation proceedings 20030501
-
Bicêtre hospital experience with sirolimus-based therapy in human renal transplantation: the Sirolimus European Renal Transplant Study.
Transplantation proceedings 20030501
-
Design of a trial comparing sirolimus plus mycophenolate mofetil versus sirolimus plus cyclosporine.
Transplantation proceedings 20030501
-
Optimizing the long-term outcome of renal transplants: opportunities created by sirolimus.
Transplantation proceedings 20030501
-
Use of sirolimus to facilitate cyclosporine avoidance or steroid withdrawal in kidney transplant recipients.
Transplantation proceedings 20030501
-
How should sirolimus be used in clinical practice?
Transplantation proceedings 20030501
-
Sirolimus experience at a Swedish transplantation center.
Transplantation proceedings 20030501
-
Sirolimus in combination with tacrolimus or mycophenolate mofetil for minimizing acute rejection risk in renal transplant recipients--a single center experience.
Transplantation proceedings 20030501
-
Sirolimus-based immunosuppression with reduce dose cyclosporine or tacrolimus after renal transplantation.
Transplantation proceedings 20030501
-
Sirolimus: a single center experience in combination with calcineurin inhibitors.
Transplantation proceedings 20030501
-
Observations on the use of sirolimus and tacrolimus in high-risk renal transplant recipients.
Transplantation proceedings 20030501
-
Sirolimus immunotherapy: the Albany Medical Center experience.
Transplantation proceedings 20030501
-
Sirolimus in pediatric transplant recipients.
Transplantation proceedings 20030501
-
Reduced and standard target concentration tacrolimus with sirolimus in renal allograft recipients.
Transplantation proceedings 20030501
-
Minimizing calcineurin inhibitor drugs in renal transplantation.
Transplantation proceedings 20030501
-
Fixed-dose sirolimus with reduced dose calcineurin inhibitor: the University of Colorado experience.
Transplantation proceedings 20030501
-
Kidney transplantation without calcineurin inhibitors using sirolimus.
Transplantation proceedings 20030501
-
Sirolimus monotherapy following Campath-1H induction.
Transplantation proceedings 20030501
-
Conversion to sirolimus in solid organ transplantation: a single-center experience.
Transplantation proceedings 20030501
-
Clinical use of rapamycin in renal allograft recipients identifies its relevant toxicity profile and raises unsolved questions: a single-center experience.
Transplantation proceedings 20030501
-
Sirolimus changes lipid concentrations and lipoprotein metabolism in kidney transplant recipients.
Transplantation proceedings 20030501
-
Cardiovascular risk factors of sirolimus compared with cyclosporine: early experience from two randomized trials in renal transplantation.
Transplantation proceedings 20030501
-
Tubular function in patients with hypokalemia induced by sirolimus after renal transplantation.
Transplantation proceedings 20030501
-
Therapeutic monitoring of sirolimus: its contribution to optimal prescription.
Transplantation proceedings 20030501
-
Use of rapamycin-impregnated stents in coronary arteries.
Transplantation proceedings 20030501
-
Sirolimus therapy in cardiac transplantation.
Transplantation proceedings 20030501
-
Safety and efficacy of sirolimus in kidney transplant patients and in patients with coronary artery disease undergoing angioplasty.
Transplantation proceedings 20030501
-
De novo use of sirolimus in immunosuppression regimens in kidney and kidney-pancreas transplantation at the University of California, San Francisco.
Transplantation proceedings 20030501
-
Sirolimus and islet transplants.
Transplantation proceedings 20030501
-
Sirolimus in liver transplantation.
Transplantation proceedings 20030501
-
Rapamycin in combination with cyclosporine or tacrolimus in liver, pancreas, and kidney transplantation.
Transplantation proceedings 20030501
-
Ten years of sirolimus therapy in orthotopic liver transplant recipients.
Transplantation proceedings 20030501
-
Preclinical results of sirolimus treatment in transplant models.
Transplantation proceedings 20030501
-
Molecular actions of sirolimus: sirolimus and mTor.
Transplantation proceedings 20030501
-
Rapamycin: signaling in vascular smooth muscle.
Transplantation proceedings 20030501
-
Protective effect of the immunosuppressant sirolimus against aortic atherosclerosis in apo E-deficient mice.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030501
-
Pharmacokinetics of an everolimus-cyclosporine immunosuppressive regimen over the first 6 months after kidney transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030501
-
The effect of combined rapamycin/cyclosporine on the changes in pro-fibrotic gene expression that occur during the development of allograft vasculopathy in rats, compared with cyclosporine or rapamycin in isolation.
Transplant international : official journal of the European Society for Organ Transplantation 20030501
-
Rapamycin throws a master switch.
Environmental health perspectives 20030501
-
Clinical experience of sirolimus-eluting stents in patients with coronary artery disease at Bangkok Heart Institute.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20030501
-
CD45RB-targeting strategies for promoting long-term allograft survival and preventingchronic allograft vasculopathy.
Transplantation 20030427
-
Randomized trial of tacrolimus in combination with sirolimus or mycophenolate mofetil in kidney transplantation: results at 6 months.
Transplantation 20030427
-
Health-related quality-of-life outcomes of sirolimus-treated kidney transplant patients after elimination of cyclosporine A: results of a 2-year randomized clinical trial.
Transplantation 20030427
-
Thymoglobulin, sirolimus, and reduced-dose cyclosporine provides excellent rejection prophylaxis for pancreas transplantation.
Transplantation 20030427
-
A phase III prospective, randomized study to evaluate concentration-controlled sirolimus (rapamune) with cyclosporine dose minimization or elimination at six months in de novo renal allograft recipients.
Transplantation 20030427
-
Mutation in TSC2 and activation of mammalian target of rapamycin signalling pathway in renal angiomyolipoma.
Lancet (London, England) 20030419
-
Downstream effectors of oncogenic ras in multiple myeloma cells.
Blood 20030415
-
Inhibition of phosphatidylinositol 3-kinase and p70S6 kinase blocks osteogenic protein-1 induction of alkaline phosphatase activity in fetal rat calvaria cells.
Journal of cellular biochemistry 20030415
-
Early withdrawal of cyclosporine A improves 1-year kidney graft structure and function in sirolimus-treated patients.
Transplantation 20030415
-
Effect of immunosuppressants on T-cell subsets observed in vivo using carboxy-fluorescein diacetate succinimidyl ester labeling.
Transplantation 20030415
-
Amino acid availability regulates S6K1 and protein synthesis in avian insulin-insensitive QM7 myoblasts.
FEBS letters 20030410
-
Pilot trial of oral rapamycin for recalcitrant restenosis.
Circulation 20030408
-
Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: progesterone receptor as a potential indicator of growth factor activity in breast cancer.
Molecular endocrinology (Baltimore, Md.) 20030401
-
Translational control by TOR and TAP42 through dephosphorylation of eIF2alpha kinase GCN2.
Genes & development 20030401
-
Delayed graft function and cast nephropathy associated with tacrolimus plus rapamycin use.
Journal of the American Society of Nephrology : JASN 20030401
-
Rapamycin attenuates load-induced cardiac hypertrophy in mice.
Circulation 20030401
-
Rapamycin mimics the incompatibility reaction in the fungus Podospora anserina.
Eukaryotic cell 20030401
-
Sirolimus delays renal allograft recovery.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030401
-
Sirolimus prolongs recovery from delayed graft function after cadaveric renal transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030401
-
The addition of sirolimus to cyclosporine and steroids inhibits the anti-equine antibody response in renal transplant recipients treated with antithymocyte globulin.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030401
-
GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR.
Molecular cell 20030401
-
Regulated expression of erythropoietin from an AAV vector safely improves the anemia of beta-thalassemia in a mouse model.
Molecular therapy : the journal of the American Society of Gene Therapy 20030401
-
[Coronary stents].
Therapeutische Umschau. Revue therapeutique 20030401
-
[Prevention of postangioplasty restenosis].
Nihon rinsho. Japanese journal of clinical medicine 20030401
-
Through the drug-eluting stent labyrinth.
Italian heart journal : official journal of the Italian Federation of Cardiology 20030401
-
Coronary angioplasty--have we conquered restenosis?
Journal of the Indian Medical Association 20030401
-
[Effect of rapamycin on NF-kappaB induction].
The Japanese journal of antibiotics 20030401
-
[Influence of erythromycin and the metabolite, EM201 on IL-2 receptor signaling].
The Japanese journal of antibiotics 20030401
-
[Suppressive effect of spiramycin on cell division].
The Japanese journal of antibiotics 20030401
-
Branched-chain amino acids promote albumin synthesis in rat primary hepatocytes through the mTOR signal transduction system.
Biochemical and biophysical research communications 20030328
-
Rapamycin inhibits E2F-dependent expression of minichromosome maintenance proteins in vascular smooth muscle cells.
Biochemical and biophysical research communications 20030328
-
The impact of cyclosporine dose reduction with or without the addition of rapamycin on functional, molecular, and histological markers of chronic allograft nephropathy.
Transplantation 20030327
-
Oral ulcers in kidney transplant recipients treated with sirolimus and mycophenolate mofetil.
Transplantation 20030327
-
New immunosuppressive agent: expectations and controversies.
Transplantation 20030327
-
Rapamycin inhibits proliferation of human neuroblastoma cells without suppression of MycN.
International journal of cancer 20030320
-
Drug-eluting stents.
The Medical letter on drugs and therapeutics 20030317
-
eIF4E/4E-BP dissociation and 4E-BP degradation in the first mitotic division of the sea urchin embryo.
Developmental biology 20030315
-
Kidney transplantation with rabbit antithymocyte globulin and sirolimus monotherapy.
Lancet (London, England) 20030315
-
Images in cardiovascular medicine. Sirolimus-eluting stent implanted in human coronary artery for 16 months: pathological findings.
Circulation 20030311
-
Energetic and structural analysis of the role of tryptophan 59 in FKBP12.
Biochemistry 20030304
-
Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process.
Nature immunology 20030301
-
Kidney function and morphology after short-term combination therapy with cyclosporine A, tacrolimus and sirolimus in the rat.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030301
-
Studies investigating pretransplant donor-specific blood transfusion, rapamycin, and the CD154-specific antibody IDEC-131 in a nonhuman primate model of skin allotransplantation.
Journal of immunology (Baltimore, Md. : 1950) 20030301
-
Macrophage labeling by SPIO as an early marker of allograft chronic rejection in a rat model of kidney transplantation.
Magnetic resonance in medicine 20030301
-
Rapamycin in cardiovascular medicine.
Internal medicine journal 20030301
-
Thrombotic micro-angiopathy with sirolimus-based immunosuppression: potentiation of calcineurin-inhibitor-induced endothelial damage?
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030301
-
Rapamycin is an effective inhibitor of human renal cancer metastasis.
Kidney international 20030301
-
Drug-eluting stents: potential applications for peripheral arterial occlusive disease.
Journal of vascular and interventional radiology : JVIR 20030301
-
Comment: delayed wound healing with sirolimus after liver transplant.
The Annals of pharmacotherapy 20030301
-
Rapamycin use and rapid withdrawal of calcineurin inhibitors in pediatric renal transplantation.
Transplantation proceedings 20030301
-
Conversion to sirolimus after kidney and liver transplantation: indications and outcomes.
Transplantation proceedings 20030301
-
Sirolimus in patients after liver transplantation.
Transplantation proceedings 20030301
-
Successful retransplantation using rapamycin in a patient with previous calcineurin inhibitor-induced posterior leukoencephalopathy syndrome.
Clinical nephrology 20030301
-
Rituximab in association with rapamycin for post-transplant lymphoproliferative disease treatment.
Transplant international : official journal of the European Society for Organ Transplantation 20030301
-
Arterial stents as a therapeutic platform.
Surgical neurology 20030301
-
[Role of Janus kinase/signal transducer and activator of transcription pathway in mediating mRNA expression of high mobility group box1 protein in the liver in septic rats].
Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20030301
-
A break-even price calculation for the use of sirolimus-eluting stents in angioplasty.
Clinical therapeutics 20030301
-
Outcomes of African-American kidney-transplant recipients treated with sirolimus, tacrolimus, and corticosteroids.
Transplantation 20030227
-
Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling.
Oncogene 20030220
-
Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: implications in the antiproliferative response to rapamycin.
Circulation 20030218
-
Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression.
Blood 20030215
-
[Sirolimus offers advantages for kidney transplant patients].
Medizinische Klinik (Munich, Germany : 1983) 20030215
-
Evidence that cyclin D1 mediates both growth and proliferation downstream of TOR in hepatocytes.
The Journal of biological chemistry 20030207
-
Inhibition of amino acid-mTOR signaling by a leucine derivative induces G1 arrest in Jurkat cells.
Biochemical and biophysical research communications 20030207
-
Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein.
Oncogene 20030206
-
In-stent stenosis: pathology and implications for the development of drug eluting stents.
Heart (British Cardiac Society) 20030201
-
Sirolimus and lymphocele formation after kidney transplantation: an immunosuppressive medication as co-factor for a surgical problem?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030201
-
Phenytoin decreases the blood concentrations of sirolimus in a liver transplant recipient: a case report.
Therapeutic drug monitoring 20030201
-
Sirolimus monotherapy in nephrotoxicity due to calcineurin inhibitors in liver transplant recipients.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20030201
-
Combination of caspofungin with inhibitors of the calcineurin pathway attenuates growth in vitro in Aspergillus species.
The Journal of antimicrobial chemotherapy 20030201
-
Insulin-like growth factor-I and the cytokines IL-3 and IL-4 promote survival of progenitor myeloid cells by different mechanisms.
Journal of neuroimmunology 20030201
-
Early experience with sirolimus in lung transplant recipients with chronic allograft rejection.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030201
-
Interstitial pneumonitis associated with sirolimus: a dilemma for lung transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030201
-
[Effects of three different immunosuppressive drugs on SD rat islet cell viability].
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030201
-
A new era in the treatment of coronary disease?
European heart journal 20030201
-
Sirolimus antirejection therapy for renal transplantation with cyclosporine-based immunosuppression: case reports.
Transplantation proceedings 20030201
-
Linear correlation between sirolimus and cyclosporine trough levels in renal transplant patients.
Transplantation proceedings 20030201
-
Rapamycin induces Smad activity in prostate cancer cell lines.
Urological research 20030201
-
Sirolimus may promote thrombotic microangiopathy.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030201
-
Rapamycin as rescue therapy in a patient supported by biventricular assist device to heart transplantation with consecutive ongoing rejection.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030201
-
Clinical development of an everolimus pediatric formulation: relative bioavailability, food effect, and steady-state pharmacokinetics.
Journal of clinical pharmacology 20030201
-
Teaching old drugs new tricks: reincarnating immunosuppressants as antifungal drugs.
Current opinion in investigational drugs (London, England : 2000) 20030201
-
Rapamycin reduces neointima formation during vascular injury.
VASA. Zeitschrift fur Gefasskrankheiten 20030201
-
Effect of sirolimus in combination with low-dose cyclosporine and steroids on acute renal allograft rejection.
Journal of the Formosan Medical Association = Taiwan yi zhi 20030201
-
[Regulatory mechanisms and the influence of immunosuppressive drugs on liver regeneration after partial hepatectomy].
Polskie Archiwum Medycyny Wewnetrznej 20030201
-
Two-year angiographic and intravascular ultrasound follow-up after implantation of sirolimus-eluting stents in human coronary arteries.
Circulation 20030128
-
Drug-eluting stents in vascular intervention.
Lancet (London, England) 20030118
-
In vivo and in vitro effects of SAR 943, a rapamycin analogue, on airway inflammation and remodeling.
American journal of respiratory and critical care medicine 20030115
-
Modeling individual variation in biomarker response to combination immunosuppression with stimulated lymphocyte responses-potential clinical implications.
Journal of immunological methods 20030115
-
Sirolimus-eluting stent for treatment of complex in-stent restenosis: the first clinical experience.
Journal of the American College of Cardiology 20030115
-
Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.
Cancer research 20030115
-
Combination therapy of mycophenolate mofetil and rapamycin in prevention of chronic renal allograft rejection in the rat.
Transplantation 20030115
-
Improved freedom from rejection after a loading dose of sirolimus.
Transplantation 20030115
-
Rapamycin impairs antigen uptake of human dendritic cells.
Transplantation 20030115
-
Severe acute renal failure after exposure to sirolimus-tacrolimus in two living donor kidney recipients.
Transplantation 20030115
-
Quantitative analysis of loading and extender acyltransferases of modular polyketide synthases.
Biochemistry 20030114
-
Sirolimus-eluting stent for the treatment of in-stent restenosis: a quantitative coronary angiography and three-dimensional intravascular ultrasound study.
Circulation 20030107
-
Rapamycin-induced G1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin.
Blood 20030101
-
Modulation of the electrophoretic mobility of the linker for activation of T cells (LAT) by the calcineurin inhibitors CsA and FK506: LAT is a potential substrate for PKC and calcineurin signaling pathways.
Cellular signalling 20030101
-
Creating polyketide diversity through genetic engineering.
Frontiers in bioscience : a journal and virtual library 20030101
-
Effects of FK506 on [Ca2+]i differ in mouse and rabbit ventricular myocytes.
The Journal of pharmacology and experimental therapeutics 20030101
-
Differential regulation of lipogenesis and leptin production by independent signaling pathways and rosiglitazone during human adipocyte differentiation.
Diabetes 20030101
-
The product of the UTH1 gene, required for Bax-induced cell death in yeast, is involved in the response to rapamycin.
Molecular microbiology 20030101
-
Drug-eluting stents to prevent reblockage of coronary arteries.
The Journal of cardiovascular nursing 20030101
-
Tacrolimus and sirolimus decrease oxidative phosphorylation of isolated rat kidney mitochondria.
British journal of pharmacology 20030101
-
[Opening of ATP-sensitive potassium channel attenuates cardiac remodeling induced by chronic inhibition of nitric oxide synthesis].
Journal of cardiology 20030101
-
Metabolic screening of mammalian cell cultures using well-plates.
Biotechnology progress 20030101
-
Steroid-refractory graft-vs.-host disease: past, present and future.
Pediatric transplantation 20030101
-
[Edema of the eyelids caused by sirolimus in renal transplant recipients].
Annales de dermatologie et de venereologie 20030101
-
Sirolimus eluting stent: a new era in interventional cardiology?
Current pharmaceutical design 20030101
-
Synergistic effect of vincristine with tacrolimus or sirolimus in prevention of acute heart allograft rejection in the rat.
Microsurgery 20030101
-
[Epstein Barr viral load monitoring in mononuclear lymphocytes and serum of renal transplant recipients using a quantitative PCR protocol].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20030101
-
Morphological and biochemical effects of immunosuppressive drugs in a capillary tube assay for endothelial dysfunction.
Clinical transplantation 20030101
-
A pilot protocol of a calcineurin-inhibitor free regimen for kidney transplant recipients of marginal donor kidneys or with delayed graft function.
Clinical transplantation 20030101
-
[Therapeutic drug monitoring of mycophenolate mofetil, sirolimus and cyclosporine at C2].
Annales de biologie clinique 20030101
-
c-Myc oncoprotein: cell cycle-related events and new therapeutic challenges in cancer and cardiovascular diseases.
Cell cycle (Georgetown, Tex.) 20030101
-
A bicyclic monoterpene diol and UVB stimulate BRCA1 phosphorylation in human keratinocytes.
Photochemistry and photobiology 20030101
-
Structures of immunophilins and their ligand complexes.
Current topics in medicinal chemistry 20030101
-
Rapamycins: mechanism of action and cellular resistance.
Cancer biology & therapy 20030101
-
Oral rapamycin inhibits growth of atherosclerotic plaque in apoE knock-out mice.
Cardiovascular radiation medicine 20030101
-
[Drug releasing stents].
Archivos de cardiologia de Mexico 20030101
-
Influence of immunosuppressive drugs on dendritic cells.
Transplant immunology 20030101
-
New regimen for kidney transplants.
FDA consumer 20030101
-
New drug-device combination helps keep arteries open.
FDA consumer 20030101
-
The molecular target of rapamycin (mTOR) as a therapeutic target against cancer.
Cancer biology & therapy 20030101
-
Synergistic effects of RAD and Neoral in inhibition of host-vs.-graft and graft-vs.-host immune responses in rat small-bowel transplantation.
Microsurgery 20030101
-
Renal transplantation: basic concepts and evolution of therapy.
Journal of clinical apheresis 20030101
-
[Recent trend in interventional cardiology--drug-containing stents].
Terapevticheskii arkhiv 20030101
-
Role of calcineurin in calcium-mediated hypoxic injury to white matter.
The spine journal : official journal of the North American Spine Society 20030101
-
Cap-dependent translation and control of the cell cycle.
Progress in cell cycle research 20030101
-
Islet of Langerhans transplantation for the treatment of type 1 diabetes.
Swiss surgery = Schweizer Chirurgie = Chirurgie suisse = Chirurgia svizzera 20030101
-
[Side effects and toxicity of immunosuppressive agents].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20030101
-
Inflammation and restenosis: implications for therapy.
Annals of medicine 20030101
-
Insulin-like growth factor binding protein-6 and CCI-779, an ester analogue of rapamycin, additively inhibit rhabdomyosarcoma growth.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20030101
-
The sirolimus-eluting stent: a review of its use in the treatment of coronary artery disease.
American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101
-
Intracoronary brachytherapy following drug-eluting stent failure. It's still not time to hang up the spikes!
Cardiovascular radiation medicine 20030101
-
Kidney and pancreas transplantation at Wake Forest University Baptist Medical Center.
Clinical transplants 20030101
-
[Rapamycin: from the laboratory to the treatment of patients' arteries].
Revista espanola de cardiologia 20030101
-
Localisation and regulation of the eIF4E-binding protein 4E-BP3.
FEBS letters 20021218
-
Improved renal function in sirolimus-treated renal transplant patients after early cyclosporine elimination.
Transplantation 20021215
-
Inhibition of the mammalian target of rapamycin sensitizes U87 xenografts to fractionated radiation therapy.
Cancer research 20021215
-
Drug eluting coronary stents.
BMJ (Clinical research ed.) 20021207
-
Effects of immunosuppressants, calcineurin inhibition, and blockade of endoplasmic reticulum calcium channels on free fatty acid efflux from the ischemic/reperfused rat cerebral cortex.
Brain research 20021206
-
Influence of the new immunosuppressive combinations on arterial hypertension after renal transplantation.
Kidney international. Supplement 20021201
-
Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells.
Molecular and cellular biology 20021201
-
Clonal anergy is maintained independently of T cell proliferation.
Journal of immunology (Baltimore, Md. : 1950) 20021201
-
Programmed death-1 targeting can promote allograft survival.
Journal of immunology (Baltimore, Md. : 1950) 20021201
-
Measurement of whole blood sirolimus by an HPLC assay using solid-phase extraction and UV detection.
Therapeutic drug monitoring 20021201
-
Inhibition of autophagy in mitotic animal cells.
Traffic (Copenhagen, Denmark) 20021201
-
Differential Effect of sirolimus vs prednisolone in the treatment of sclerosing encapsulating peritonitis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20021201
-
Review of the proliferation inhibitor everolimus.
Expert opinion on investigational drugs 20021201
-
Histopathological study of intrahepatic islets transplanted in the nonhuman primate model using edmonton protocol immunosuppression.
The Journal of clinical endocrinology and metabolism 20021201
-
Sirolimus: new preparation. No tangible advance in renal transplantation.
Prescrire international 20021201
-
Evaluation for synergistic suppression of T cell responses to minor histocompatibility antigens by chloroquine in combination with tacrolimus and a rapamycin derivative, SDZ-RAD.
Bone marrow transplantation 20021201
-
Sirolimus-eluting coronary stents.
Journal of interventional cardiology 20021201
-
T-stenting with drug-eluting stents for the treatment of bifurcation in-stent restenosis.
Journal of interventional cardiology 20021201
-
Studies of cargo delivery to the vacuole mediated by autophagosomes in Saccharomyces cerevisiae.
Developmental cell 20021201
-
Effect of sirolimus on ischemia/reperfusion injury in transgenic hypertensive rat.
Transplantation proceedings 20021201
-
Basiliximab-sirolimus-prednisone induction regimen followed by delayed low-dose cyclosporine in renal transplant recipients of living donors.
Transplantation proceedings 20021201
-
Sirolimus rescue treatment in calcineurin-inhibitor nephrotoxicity after kidney transplantation.
Transplantation proceedings 20021201
-
Immunosuppression with sirolimus/tacrolimus combination in pancreas transplantation: 1-year results.
Transplantation proceedings 20021201
-
Interaction of immunosuppressive agents rapamycin and its analogue SDZ-RAD with endothelial P-gp.
Transplantation proceedings 20021201
-
Regulation of subtelomeric silencing during stress response.
Molecular cell 20021201
-
Maf1 is an essential mediator of diverse signals that repress RNA polymerase III transcription.
Molecular cell 20021201
-
New treatment for clogged coronary arteries.
Mayo Clinic health letter (English ed.) 20021201
-
[To further improve transplantation results].
Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20021201
-
Fluconazole-sirolimus drug interaction.
Transplantation 20021127
-
Images in Cardiovascular Medicine. True three-dimensional reconstructed images showing lumen enlargement after sirolimus-eluting stent implantation.
Circulation 20021126
-
Kidney transplantation with rabbit antithymocyte globulin induction and sirolimus monotherapy.
Lancet (London, England) 20021123
-
Synthetic lethality: killing cancer with cancer.
Journal of the National Cancer Institute 20021120
-
Nuclear translocation of insulin receptor substrate-1 by oncogenes and Igf-I. Effect on ribosomal RNA synthesis.
The Journal of biological chemistry 20021115
-
BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin.
Blood 20021115
-
Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast.
The Journal of biological chemistry 20021108
-
The immunosuppressant rapamycin, alone or with transforming growth factor-beta, enhances osteoclast differentiation of RAW264.7 monocyte-macrophage cells in the presence of RANK-ligand.
Calcified tissue international 20021101
-
Different mechanisms are utilized by HIV-1 Nef and staphylococcal enterotoxin A to control and regulate interleukin-10 production.
Immunology letters 20021101
-
The immunosuppressant rapamycin represses human immunodeficiency virus type 1 replication.
Antimicrobial agents and chemotherapy 20021101
-
Combined effects of calcineurin inhibitors or sirolimus with anti-CD40L mAb on alloengraftment under nonmyeloablative conditions.
Blood 20021101
-
Effects of the combination of rapamycin with tacrolimus or cyclosporin on experimental intimal hyperplasia.
The British journal of surgery 20021101
-
Sirolimus (Rapamune) in renal transplantation.
Current opinion in nephrology and hypertension 20021101
-
Therapeutic drug monitoring of immunosuppressive drugs in kidney transplantation.
Current opinion in nephrology and hypertension 20021101
-
Drug-eluting stent: the 'magic bullet' for prevention of restenosis?
Basic research in cardiology 20021101
-
Fate of side branches after coronary arterial sirolimus-eluting stent implantation.
The American journal of cardiology 20021101
-
New insights into the interactions between T-cell costimulatory blockade and conventional immunosuppressive drugs.
Annals of surgery 20021101
-
Ras/Erk signaling is essential for activation of protein synthesis by Gq protein-coupled receptor agonists in adult cardiomyocytes.
Circulation research 20021101
-
Inhibitors of mTOR reverse doxorubicin resistance conferred by PTEN status in prostate cancer cells.
Cancer research 20021101
-
Ca(2+)-dependent interaction between FKBP12 and calcineurin regulates activity of the Ca(2+) release channel in skeletal muscle.
Biophysical journal 20021101
-
Sirolimus and FTY720: new approaches to transplant immunosuppression.
Transplantation proceedings 20021101
-
Effect of rapamycin and prednisolone in differentiated THP-1 and U937 cells.
Transplantation proceedings 20021101
-
Pharmacodynamics of sirolimus and cyclosporine combination therapy.
Transplantation proceedings 20021101
-
Sirolimus attenuates the expression of metalloproteinase-2 and -9 and inhibits intimal hyperplasia following balloon angioplasty.
Transplantation proceedings 20021101
-
Rituximab and rapamycin for posttransplant lymphoproliferative disease treatment: report of three cases.
Transplantation proceedings 20021101
-
Flow cytometric detection of intracellular IL-12 release: in vitro effect of widely used immunosuppressants.
International immunopharmacology 20021101
-
[Treatment of diabetes mellitus in patients after renal transplantation].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20021101
-
[Effect of immunosuppressive treatment on diurnal profile of blood pressure].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20021101
-
Systemic drug therapy for restenosis: 'déjà vu all over again'.
Circulation 20021029
-
Oral everolimus inhibits in-stent neointimal growth.
Circulation 20021029
-
Kidney transplantation without calcineurin inhibitor drugs: a prospective, randomized trial of sirolimus versus cyclosporine.
Transplantation 20021027
-
Sirolimus-eluting coronary stents.
The New England journal of medicine 20021017
-
Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors.
Cancer research 20021015
-
The group I metabotropic glutamate receptor agonist (S)-3,5-dihydroxyphenylglycine induces a novel form of depotentiation in the CA1 region of the hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20021015
-
Oral efficacy of the new immunomodulator FTY720 in cynomolgus monkey kidney allotransplantation, given alone or in combination with cyclosporine or RAD.
Transplantation 20021015
-
Multiple signalling pathways mediate insulin-stimulated gene expression in 3T3-L1 adipocytes.
Biochimica et biophysica acta 20021011
-
Angiographic findings of the multicenter Randomized Study With the Sirolimus-Eluting Bx Velocity Balloon-Expandable Stent (RAVEL): sirolimus-eluting stents inhibit restenosis irrespective of the vessel size.
Circulation 20021008
-
Phosphorylation-dependent interaction of the asialoglycoprotein receptor with molecular chaperones.
The Journal of biological chemistry 20021004
-
Identification of TOR signaling complexes: more TORC for the cell growth engine.
Cell 20021004
-
Proliferation of IL-6-independent multiple myeloma does not require the activity of extracellular signal-regulated kinases (ERK1/2).
Journal of cellular physiology 20021001
-
Activation of multiple signaling modules is critical in angiotensin IV-induced lung endothelial cell proliferation.
American journal of physiology. Lung cellular and molecular physiology 20021001
-
The FKBP12-rapamycin-associated protein (FRAP) is a CLIP-170 kinase.
EMBO reports 20021001
-
Cyclosporin-A differentially affects apoptosis during in vivo rat thymocyte maturation.
Scandinavian journal of immunology 20021001
-
A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling.
Biochemical pharmacology 20021001
-
Sirolimus oral absorption in rats is increased by ketoconazole but is not affected by D-alpha-tocopheryl poly(ethylene glycol 1000) succinate.
The Journal of pharmacology and experimental therapeutics 20021001
-
Hepatocyte growth factor induced human trophoblast motility involves phosphatidylinositol-3-kinase, mitogen-activated protein kinase, and inducible nitric oxide synthase.
Experimental cell research 20021001
-
Contrasting impacts of immunosuppressive agents (rapamycin, FK506, cyclosporin A, and dexamethasone) on bidirectional dendritic cell-T cell interaction during antigen presentation.
Journal of immunology (Baltimore, Md. : 1950) 20021001
-
Impact of immunosuppressive therapy on recurrence of hepatitis C.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20021001
-
Sirolimus eluting stent in the treatment of atherosclerosis coronary artery disease.
Minerva cardioangiologica 20021001
-
Drug-eluting stents.
Minerva cardioangiologica 20021001
-
Drug-eluting stent: the emerging technique for the prevention of restenosis.
Minerva cardioangiologica 20021001
-
Drug-eluting stents: clinical experiences and perspectives.
Minerva cardioangiologica 20021001
-
Drug eluting stents: managing coronary artery stenosis following PTCA.
Issues in emerging health technologies 20021001
-
Cardiovascular toxicities of immunosuppressive agents.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20021001
-
Constitutive activation of p70S6k in cancer cells.
Archives of pharmacal research 20021001
-
Dimerizer-regulated gene expression.
Current opinion in biotechnology 20021001
-
Calcineurin inhibitors and sirolimus: mechanisms of action and applications in dermatology.
Clinical and experimental dermatology 20021001
-
Sirolimus-eluting stents: the novel application of basic science to coronary artery disease.
Irish medical journal 20021001
-
The '0%' restenosis study.
Italian heart journal : official journal of the Italian Federation of Cardiology 20021001
-
Clinical development of mammalian target of rapamycin inhibitors.
Hematology/oncology clinics of North America 20021001
-
Incidence, therapy, and consequences of lymphocele after sirolimus-cyclosporine-prednisone immunosuppression in renal transplant recipients.
Transplantation 20020927
-
Artificial mammalian gene regulation networks-novel approaches for gene therapy and bioengineering.
Journal of biotechnology 20020925
-
Persistent inhibition of neointimal hyperplasia after sirolimus-eluting stent implantation: long-term (up to 2 years) clinical, angiographic, and intravascular ultrasound follow-up.
Circulation 20020924
-
Convergence of the target of rapamycin and the Snf1 protein kinase pathways in the regulation of the subcellular localization of Msn2, a transcriptional activator of STRE (Stress Response Element)-regulated genes.
The Journal of biological chemistry 20020920
-
Sirolimus-eluting stents for the treatment of obstructive superficial femoral artery disease: six-month results.
Circulation 20020917
-
Sirolimus-induced leukocytoclastic vasculitis.
Transplantation 20020915
-
American Chemical Society meeting. Chemists search for solutions.
Science (New York, N.Y.) 20020913
-
TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation.
Current biology : CB 20020903
-
Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling.
Nature cell biology 20020901
-
Role of the p70 S6 kinase cascade in neutrophilic differentiation and proliferation of HL-60 cells-a study of transferrin receptor-positive and -negative cells obtained from dimethyl sulfoxide- or retinoic acid-treated HL-60 cells.
Archives of biochemistry and biophysics 20020901
-
Effect of insulin-like growth factor II on protecting myoblast cells against cisplatin-induced apoptosis through p70 S6 kinase pathway.
Neoplasia (New York, N.Y.) 20020901
-
Mycophenolic acid inhibits IL-2-dependent T cell proliferation, but not IL-2-dependent survival and sensitization to apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 20020901
-
Delayed wound healing with sirolimus after liver transplant.
The Annals of pharmacotherapy 20020901
-
Nelfinavir, a protease inhibitor, increases sirolimus levels in a liver transplantation patient: a case report.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20020901
-
No delayed restenosis at 18 months after implantation of sirolimus-eluting stent.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20020901
-
Drug-eluting stents for the prevention of restenosis: Standing the test of time.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20020901
-
Enhanced sensitivity of multiple myeloma cells containing PTEN mutations to CCI-779.
Cancer research 20020901
-
Comparative study of cyclosporine and tacrolimus vs newer immunosuppressants mycophenolate mofetil and rapamycin on coronary endothelial function.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20020901
-
Everolimus (Certican) in combination with neoral in pediatric renal transplant recipients: interim analysis after 3 months.
Transplantation proceedings 20020901
-
Long-term pharmacokinetics of the metabolites of everolimus and cyclosporine in renal transplant recipients.
Transplantation proceedings 20020901
-
Sirolimus in late acute OKT3-resistant and/or steroid-resistant rejection after simultaneous pancreas and kidney transplantation.
Transplantation proceedings 20020901
-
Onset of liver regeneration after subtotal resection is inhibited by the use of new immunosuppressive drugs.
Transplantation proceedings 20020901
-
Can we prevent in-stent restenosis?
Current opinion in cardiology 20020901
-
Care of the kidney transplant recipient. Vigilant monitoring creates the best outcome.
Postgraduate medicine 20020901
-
[Drug-eluding stents: bis repetita?].
Archives des maladies du coeur et des vaisseaux 20020901
-
Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.
Molecular cell 20020901
-
Goosebumps.
Lancet (London, England) 20020831
-
Regulation of ribosomal S6 kinase 2 by mammalian target of rapamycin.
The Journal of biological chemistry 20020830
-
Immunologic mechanisms in tolerance produced in mice with nonradiation-based lymphoablation and donor-specific bone marrow.
Transplantation 20020827
-
Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM).
The Journal of biological chemistry 20020823
-
Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells.
Oncogene 20020815
-
Intravascular ultrasound findings in the multicenter, randomized, double-blind RAVEL (RAndomized study with the sirolimus-eluting VElocity balloon-expandable stent in the treatment of patients with de novo native coronary artery Lesions) trial.
Circulation 20020813
-
Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway.
The Journal of biological chemistry 20020802
-
Effect of immunosuppressive agents on glucocorticoid receptor function in A6 cells.
American journal of physiology. Renal physiology 20020801
-
Rapamycin inhibits macropinocytosis and mannose receptor-mediated endocytosis by bone marrow-derived dendritic cells.
Blood 20020801
-
Sirolimus-based immunosuppression for transplant-associated thrombotic microangiopathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020801
-
Sirolimus lowers myeloperoxidase and p-ANCA titers in a pediatric patient before kidney transplantation.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20020801
-
Signalling pathways and combinatory effects of insulin and amino acids in isolated rat hepatocytes.
European journal of biochemistry 20020801
-
Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes.
European journal of biochemistry 20020801
-
Transmitting the signal of excess nitrogen in Saccharomyces cerevisiae from the Tor proteins to the GATA factors: connecting the dots.
FEMS microbiology reviews 20020801
-
Multiple ion isolation applications in FT-ICR MS: exact-mass MSn internal calibration and purification/interrogation of protein-drug complexes.
Analytical chemistry 20020801
-
Rapamycin blocks the generation of regulatory T cells facilitated by posttransplant infusion of donor T cells through increasing the apoptosis of thymic CD4(+)CD25(+) cells.
Transplantation proceedings 20020801
-
Sirolimus inhibits growth of human hepatoma cells in contrast to tacrolimus which promotes cell growth.
Transplantation proceedings 20020801
-
Inhibition of IL-12 signaling Stat4/IFN-gamma pathway by rapamycin is associated with impaired dendritic [correction of dendritc] cell function.
Transplantation proceedings 20020801
-
Influence of immunosuppressive drugs on intestinal epithelial transport function.
Transplantation proceedings 20020801
-
Effect of rapamycin in combination with calcineurin inhibitors, FK506 and cyclosporin, following arterial injury.
Transplantation proceedings 20020801
-
Sirolimus-based immunosuppressive [correction of immunosuppresive] protocol for calcineurin sparing in liver transplantation.
Transplantation proceedings 20020801
-
Randomized trial of three different immunosuppressive regimens to prevent chronic renal allograft rejection.
Transplantation proceedings 20020801
-
Early experience using calcineurin-free protocol in recipients of high-risk cadaver renal transplants.
Transplantation proceedings 20020801
-
Medium-term outcome using sirolimus-tacrolimus combination in adult renal transplant recipients.
Transplantation proceedings 20020801
-
A pilot trial of tacrolimus, sirolimus, and steroids in renal transplant recipients.
Transplantation proceedings 20020801
-
A retrospective analysis of a sirolimus/prograf regimen for the prevention of acute rejection in recipients of primary mismatched renal allografts.
Transplantation proceedings 20020801
-
Sirolimus-based steroid-free maintenance immunosuppression.
Transplantation proceedings 20020801
-
Increased frequency of lymphoceles under treatment with sirolimus following renal transplantation: a single center experience.
Transplantation proceedings 20020801
-
Sirolimus and tacrolimus in clinical cardiac transplantation.
Transplantation proceedings 20020801
-
Can acute rejection be prevented in SPK transplantation?
Transplantation proceedings 20020801
-
Rejection-free protocol using sirolimus-tacrolimus combination for pediatric renal transplant recipients.
Transplantation proceedings 20020801
-
Improved lipid profile and blood sugar control in pediatric renal transplant recipients using sirolimus-tacrolimus combination.
Transplantation proceedings 20020801
-
Pharmacodynamics of sirolimus in transplanted children receiving tacrolimus.
Transplantation proceedings 20020801
-
Preliminary immunosuppression withdrawal strategies with sirolimus in children with liver transplants.
Transplantation proceedings 20020801
-
Nutrient-hormone interaction in the ovine liver: methionine supply selectively modulates growth hormone-induced IGF-I gene expression.
The Journal of endocrinology 20020801
-
Effects of sirolimus on plasma lipids, lipoprotein levels, and fatty acid metabolism in renal transplant patients.
Journal of lipid research 20020801
-
Loss of ypk1 function causes rapamycin sensitivity, inhibition of translation initiation and synthetic lethality in 14-3-3-deficient yeast.
Genetics 20020801
-
CCI-779 Wyeth.
Current opinion in investigational drugs (London, England : 2000) 20020801
-
The neuronal choline transporter CHT1 is regulated by immunosuppressor-sensitive pathways.
Journal of neurochemistry 20020801
-
Outcomes of African American kidney transplant recipients treated with sirolimus, tacrolimus, and corticosteroids.
Transplantation 20020727
-
VIIa/tissue factor interaction results in a tissue factor cytoplasmic domain-independent activation of protein synthesis, p70, and p90 S6 kinase phosphorylation.
The Journal of biological chemistry 20020726
-
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.
Cell 20020726
-
Assessment of sirolimus concentrations in whole blood by high-performance liquid chromatography with ultraviolet detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020715
-
The impact of novel immunosuppressive agents on infections in organ transplant recipients and the interactions of these agents with antimicrobials.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020701
-
Termination of cardiac Ca(2+) sparks: an investigative mathematical model of calcium-induced calcium release.
Biophysical journal 20020701
-
Constitutive and regulated expression of processed insulin following in vivo hepatic gene transfer.
Gene therapy 20020701
-
Regulation of endogenous gene expression with a small-molecule dimerizer.
Nature biotechnology 20020701
-
Sirolimus steady-state trough concentrations are not affected by bolus methylprednisolone therapy in renal allograft recipients.
British journal of clinical pharmacology 20020701
-
Effects of sirolimus on lipids in renal allograft recipients: an analysis using the Framingham risk model.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20020701
-
Mechanisms involved in responses to the poroxisome proliferator WY-14,643 on gap junctional intercellular communication in V79 hamster fibroblasts.
Toxicology and applied pharmacology 20020701
-
Successful treatment of tacrolimus-associated thrombotic microangiopathy with sirolimus conversion and plasma exchange.
Clinical nephrology 20020701
-
An unexpected inhibitory effect of rapamycin against germination of spores of Bacillus brevis strain Nagano.
The Journal of antibiotics 20020701
-
What is 'the matter' with restenosis in 2002?
Circulation 20020625
-
c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells.
The Journal of biological chemistry 20020621
-
Global and specific translational control by rapamycin in T cells uncovered by microarrays and proteomics.
The Journal of biological chemistry 20020621
-
Effect of rapamycin on the cyclosporin A-resistant CD28-mediated costimulatory pathway.
Blood 20020615
-
Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E.
Genes & development 20020615
-
Mks1p is required for negative regulation of retrograde gene expression in Saccharomyces cerevisiae but does not affect nitrogen catabolite repression-sensitive gene expression.
The Journal of biological chemistry 20020607
-
Sirolimus-eluting coronary stents.
The New England journal of medicine 20020606
-
A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization.
The New England journal of medicine 20020606
-
Quantification and stability of everolimus (SDZ RAD) in human blood by high-performance liquid chromatography-electrospray tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020605
-
Insulinlike growth factor-I signaling in multiple myeloma: downstream elements, functional correlates, and pathway cross-talk.
Blood 20020601
-
A clinical pharmacokinetic study of tacrolimus and sirolimus combination immunosuppression comparing simultaneous to separated administration.
Therapeutic drug monitoring 20020601
-
Effect of rifampin on apparent clearance of everolimus.
The Annals of pharmacotherapy 20020601
-
Rapid liquid chromatography-tandem mass spectrometry routine method for simultaneous determination of sirolimus, everolimus, tacrolimus, and cyclosporin A in whole blood.
Clinical chemistry 20020601
-
In vitro evaluation of motilin agonism by macrolide immunosuppressive drugs.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020601
-
Sirolimus tolerability in a kidney transplant recipient with acute intermittent porphyria.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020601
-
Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020601
-
The effects of rapamycin in murine peripheral nerve isografts and allografts.
Plastic and reconstructive surgery 20020601
-
Rapamycin induces binding activity to the terminal oligopyrimidine tract of ribosomal protein mRNA in rats.
Archives of biochemistry and biophysics 20020601
-
Sirolimus/cyclosporine/tacrolimus interactions on bile flow and biliary excretion of immunosuppressants in a subchronic bile fistula rat model.
British journal of pharmacology 20020601
-
Implication of alpha4 phosphoprotein and the rapamycin-sensitive mammalian target-of-rapamycin pathway in prolactin receptor signalling.
The Journal of endocrinology 20020601
-
Combined immunosuppression with cyclosporine, rapamycin, and mycophenolate mofetil controls rejection with minimal nutritional impact in experimental small intestinal transplantation.
Transplantation proceedings 20020601
-
Influence of a novel rapamycin analogon SDZ RAD on endothelial tissue factor and adhesion molecule expression.
Transplantation proceedings 20020601
-
Prolongation of fully allogeneic skin graft survival in the rat by combined administration of costimulatory blockade and sirolimus.
Transplantation proceedings 20020601
-
Role of immunosuppressive drugs in the development of tissue-invasive cytomegalovirus infection in renal transplant recipients.
Transplantation proceedings 20020601
-
New developments in immunosuppressive therapy in renal transplantation.
Expert opinion on biological therapy 20020601
-
Rapamycin and T cell costimulatory blockade as post-transplant treatment promote fully MHC-mismatched allogeneic bone marrow engraftment under irradiation-free conditioning therapy.
Bone marrow transplantation 20020601
-
The rapamycin analogue SDZ RAD attenuates bleomycin-induced pulmonary fibrosis in rats.
The European respiratory journal 20020601
-
Coated stents: a novel approach to prevent in-stent restenosis.
Italian heart journal : official journal of the Italian Federation of Cardiology 20020601
-
Modern strategies to prevent coronary restenosis.
Italian heart journal : official journal of the Italian Federation of Cardiology 20020601
-
Control of proteolysis by norepinephrine and insulin in brown adipocytes: role of ATP, phosphatidylinositol 3-kinase, and p70 S6K.
Canadian journal of physiology and pharmacology 20020601
-
[Metabolic modifications related to immunosuppressive drugs].
Revue medicale de Bruxelles 20020601
-
Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site.
The Journal of biological chemistry 20020531
-
Intestinal transplantation before and after the introduction of sirolimus.
Transplantation 20020527
-
Rapamycin blocks tumor progression: unlinking immunosuppression from antitumor efficacy.
Transplantation 20020527
-
[Consistent success with coated stents. Coronary arteries stay open longer].
MMW Fortschritte der Medizin 20020523
-
Ro 31-6045, the inactive analogue of the protein kinase C inhibitor Ro 31-8220, blocks in vivo activation of p70(s6k)/p85(s6k): implications for the analysis of S6K signalling.
FEBS letters 20020522
-
Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load.
The Journal of biological chemistry 20020517
-
Myogenic differentiation is dependent on both the kinase function and the N-terminal sequence of mammalian target of rapamycin.
The Journal of biological chemistry 20020510
-
Rapamycin partially prevents insulin resistance induced by chronic insulin treatment.
Biochemical and biophysical research communications 20020510
-
Images in cardiovascular medicine. Left main rapamycin-coated stent: invasive versus noninvasive angiographic follow-up.
Circulation 20020507
-
Signal pathways involved in activation of p70S6K and phosphorylation of 4E-BP1 following exposure of multiple myeloma tumor cells to interleukin-6.
The Journal of biological chemistry 20020503
-
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy.
Human molecular genetics 20020501
-
Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion.
The EMBO journal 20020501
-
Role of apoptosis in the pathogenesis of acute renal failure.
Current opinion in nephrology and hypertension 20020501
-
How should the immunosuppressive regimen be managed in patients with established chronic allograft failure?
Kidney international. Supplement 20020501
-
Sirolimus allows renal recovery in lung and heart transplant recipients with chronic renal impairment.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20020501
-
Induction of apoptosis and modulation of activation and effector function in T cells by immunosuppressive drugs.
Clinical and experimental immunology 20020501
-
ARTS I -- the rapamycin eluting stent; ARTS II -- the rosy prophecy.
European heart journal 20020501
-
Muscarinic acetylcholine receptor activation induces Ca2+ mobilization and Na+/K+-ATPase activity inhibition in eel enterocytes.
The Journal of endocrinology 20020501
-
Hemolytic uremic syndrome after renal transplantation: immunosuppressive therapy with rapamycin.
Nephron 20020501
-
Protein modulators made to order.
Chemistry & biology 20020501
-
Transcriptional response pathways in a yeast strain sensitive to saframycin a and a more potent analog: evidence for a common basis of activity.
Chemistry & biology 20020501
-
Initial experience using rapamycin immunosuppression in pediatric intestinal transplant recipients.
Transplantation proceedings 20020501
-
Improved results in small bowel transplantation using sirolimus.
Transplantation proceedings 20020501
-
Tacrolimus, daclizumab, sirolimus, and budesonide after small bowel transplantation in order to reduce nephrotoxicity.
Transplantation proceedings 20020501
-
Washing out of lipophilic compounds induces a transient increase in the passive Ca(2+) leak in permeabilized A7r5 cells.
Cell calcium 20020501
-
Sirolimus does not exhibit nephrotoxicity compared to cyclosporine in renal transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20020501
-
Twenty-eight-day efficacy and phamacokinetics of the sirolimus-eluting stent.
Coronary artery disease 20020501
-
Drug coating improves stent performance.
Health news (Waltham, Mass.) 20020501
-
Delayed low-level calcineurin inhibition promotes allospecific tolerance induction by posttransplantation donor leukocyte infusion.
Transplantation 20020427
-
4E-binding proteins, the suppressors of eukaryotic initiation factor 4E, are down-regulated in cells with acquired or intrinsic resistance to rapamycin.
The Journal of biological chemistry 20020419
-
Quick guide: target of rapamycin.
Current biology : CB 20020416
-
Msn2p/Msn4p act as a key transcriptional activator of yeast cytoplasmic thiol peroxidase II.
The Journal of biological chemistry 20020405
-
Rapamycin eluting stent: the onset of a new era in interventional cardiology.
Heart (British Cardiac Society) 20020401
-
Identification of a novel route of extraction of sirolimus in human small intestine: roles of metabolism and secretion.
The Journal of pharmacology and experimental therapeutics 20020401
-
Translational control of cell fate: availability of phosphorylation sites on translational repressor 4E-BP1 governs its proapoptotic potency.
Molecular and cellular biology 20020401
-
Fighting restenosis from the inside out.
Harvard heart letter : from Harvard Medical School 20020401
-
Rapamune. New tablet combats kidney rejection.
Nursing 20020401
-
Long-term care of pediatric renal transplant patients: from bench to bedside.
Current opinion in pediatrics 20020401
-
Single-dose pharmacokinetics and tolerability of everolimus in stable pediatric renal transplant patients.
Pediatric transplantation 20020401
-
Efficacy and toxicity of a protocol using sirolimus, tacrolimus and daclizumab in a nonhuman primate renal allotransplant model.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20020401
-
The role of phosphatidylinositol 3-kinase, rho family GTPases, and STAT3 in Ros-induced cell transformation.
The Journal of biological chemistry 20020329
-
Long-term kidney graft survival by delayed T cell ablative treatment in rhesus monkeys.
Transplantation 20020327
-
Compared to mycophenolate mofetil, rapamycin induces significant changes on growth factors and growth factor receptors in the early days post-kidney transplantation.
Transplantation 20020327
-
Exposure-response relationships for everolimus in de novo kidney transplantation: defining a therapeutic range.
Transplantation 20020327
-
Insulin regulation of insulin-like growth factor-binding protein-1 gene expression is dependent on the mammalian target of rapamycin, but independent of ribosomal S6 kinase activity.
The Journal of biological chemistry 20020322
-
Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner.
The Journal of biological chemistry 20020322
-
Phosphorylation of 4E-BP1 is mediated by the p38/MSK1 pathway in response to UVB irradiation.
The Journal of biological chemistry 20020315
-
De novo hemolytic uremic syndrome after kidney transplantation in patients treated with cyclosporine-sirolimus combination.
Transplantation 20020315
-
Regulation of cap-dependent translation by insulin-like growth factor-1 in neuronal cells.
Biochemical and biophysical research communications 20020301
-
The future role of target of rapamycin inhibitors in renal transplantation.
Current opinion in urology 20020301
-
Stent-based antirestenotic coatings (sirolimus/paclitaxel).
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20020301
-
Drug-eluting stents for the prevention of restenosis: in quest for the Holy Grail.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20020301
-
Combination therapy with sirolimus and interleukin-2 prevents spontaneous and recurrent autoimmune diabetes in NOD mice.
Diabetes 20020301
-
Strategies to reduce toxicities and improve outcomes in renal transplant recipients.
Pharmacotherapy 20020301
-
Long-term viability of articular cartilage after microsurgical whole-joint transplantation and immunosuppression with rapamycin, mycophenolate mofetil, and tacrolimus.
The Journal of hand surgery 20020301
-
The genome-wide localization of Rsc9, a component of the RSC chromatin-remodeling complex, changes in response to stress.
Molecular cell 20020301
-
Simultaneous quantification of sirolimus, everolimus, tacrolimus and cyclosporine by liquid chromatography-mass spectrometry (LC-MS).
Clinical chemistry and laboratory medicine 20020301
-
Mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitors restore anoikis sensitivity in human breast cancer cell lines with a constitutively activated extracellular-regulated kinase (ERK) pathway.
Molecular cancer therapeutics 20020301
-
Bibliography. Current world literature. Renal medicine and renal transplantation.
Current opinion in urology 20020301
-
FK506 induces chondrogenic differentiation of clonal mouse embryonic carcinoma cells, ATDC5.
European journal of pharmacology 20020222
-
Effect of topical immunomodulators on acute allergic inflammation and bronchial hyperresponsiveness in sensitised rats.
European journal of pharmacology 20020222
-
Overcoming restenosis with sirolimus: from alphabet soup to clinical reality.
Lancet (London, England) 20020216
-
Cyclosporin A, FK506 and rapamycin produce multiple, temporally distinct, effects on memory following single-trial, passive avoidance training in the chick.
Brain research 20020215
-
Early expression of myocardial HIF-1alpha in response to mechanical stresses: regulation by stretch-activated channels and the phosphatidylinositol 3-kinase signaling pathway.
Circulation research 20020208
-
Identification of genes coding enzymes for ascomycin tetra-hydropyranose ring formation.
International journal of molecular medicine 20020201
-
Update on pharmacokinetic/pharmacodynamic studies with FTY720 and sirolimus.
Therapeutic drug monitoring 20020201
-
Early clinical experience with a novel rapamycin derivative.
Therapeutic drug monitoring 20020201
-
International Federation of Clinical Chemistry/International Association of Therapeutic Drug Monitoring and Clinical Toxicology working group on immunosuppressive drug monitoring.
Therapeutic drug monitoring 20020201
-
BCR signal through alpha 4 is involved in S6 kinase activation and required for B cell maturation including isotype switching and V region somatic hypermutation.
International immunology 20020201
-
Calcineurin inhibitor-free CD28 blockade-based protocol protects allogeneic islets in nonhuman primates.
Diabetes 20020201
-
Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor.
Nature medicine 20020201
-
New tools for prevention of restenosis could decrease the 'oculo-stento' reflex.
Cardiovascular research 20020201
-
Pharmacokinetic and pharmacodynamic assessments of HMG-CoA reductase inhibitors when coadministered with everolimus.
Journal of clinical pharmacology 20020201
-
Effect of food on everolimus absorption: quantification in healthy subjects and a confirmatory screening in patients with renal transplants.
Pharmacotherapy 20020201
-
Mammalian target of rapamycin (mTOR): pro- and anti-apoptotic.
Cell death and differentiation 20020201
-
A novel conditional Akt 'survival switch' reversibly protects cells from apoptosis.
Gene therapy 20020201
-
Protein phosphatase 2A on track for nutrient-induced signalling in yeast.
Molecular microbiology 20020201
-
Combination therapy with low dose sirolimus and tacrolimus is synergistic in preventing spontaneous and recurrent autoimmune diabetes in non-obese diabetic mice.
Diabetologia 20020201
-
[Radioactive stents: problems and potential solutions].
Herz 20020201
-
Early cyclosporine a withdrawal in kidney transplant recipients under a sirolimus-based immunosuppressive regimen: pathological study of graft biopsies at 1-year posttransplant.
Transplantation proceedings 20020201
-
Immunosuppression with sirolimus, cyclosporyne, and prednisone in renal transplantation.
Transplantation proceedings 20020201
-
The limitations of calcineurin and mTOR inhibitors: new directions for immunosuppressive strategies.
Transplantation proceedings 20020201
-
Inhibitors of mammalian target of rapamycin as novel antitumor agents: from bench to clinic.
Current opinion in investigational drugs (London, England : 2000) 20020201
-
Swinging the vote for rapamycin.
Nature reviews. Cancer 20020201
-
Coating stents with antirestenotic drugs: the blunderbuss or the magic bullet?
Circulation 20020129
-
Rapamycin increases transforming growth factor-beta mRNA expression in immortalized rat proximal renal tubular cells.
Transplantation 20020127
-
Increased activity of c-Src and Csk in fibroblasts transformed by v-src oncogene.
Biochemical and biophysical research communications 20020118
-
Igs from patients with Graves' disease induce the expression of T cell chemoattractants in their fibroblasts.
Journal of immunology (Baltimore, Md. : 1950) 20020115
-
Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin.
Blood 20020115
-
Cell cycle kinesis in lymphocytes in the diagnosis of Alzheimer's disease.
Neuroscience letters 20020111
-
Autocrine heregulin generates growth factor independence and blocks apoptosis in colon cancer cells.
Oncogene 20020103
-
Inhibition of PI3K/p70 S6K and p38 MAPK cascades increases osteoblastic differentiation induced by BMP-2.
FEBS letters 20020102
-
FK506 enhanced osteoblastic differentiation in mesenchymal cells.
Cell biology international 20020101
-
Synergism of RAD and cyclosporin A in prevention of acute rat corneal allograft rejection.
Cornea 20020101
-
MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders.
BMC cell biology 20020101
-
Differential influence of two cyclosporine formulations on everolimus pharmacokinetics: a clinically relevant pharmacokinetic interaction.
Journal of clinical pharmacology 20020101
-
Post-liver transplantation immunosuppression: the song does not remain the same.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20020101
-
Preparing for the introduction of new technologies: who is going to pay for them?
The Journal of cardiovascular management : the official journal of the American College of Cardiovascular Administrators 20020101
-
Cytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: implications for rheumatoid arthritis.
Arthritis research 20020101
-
Vector algebra in the analysis of genome-wide expression data.
Genome biology 20020101
-
Current immunosuppression in liver transplantation.
American journal of therapeutics 20020101
-
Quantification of sirolimus by liquid chromatography-tandem mass spectrometry using on-line solid-phase extraction.
Clinical chemistry and laboratory medicine 20020101
-
Novel pharmacotherapeutic approaches to prevention and treatment of GVHD.
Drugs 20020101
-
Newer immunosuppressive drugs: their potential role in rheumatoid arthritis therapy.
Drugs 20020101
-
Role of mTOR in the degradation of IRS-1: regulation of PP2A activity.
Journal of cellular biochemistry 20020101
-
Drug-eluting stents in the treatment of atherosclerotic coronary heart disease.
Indian heart journal 20020101
-
[The novel immunodepressant rapamune].
Eksperimental'naia i klinicheskaia farmakologiia 20020101
-
Single-agent immunosuppression after liver transplantation: what is possible?
Drugs 20020101
-
Optimization and direct comparison of the dimerizer and reverse tet transcriptional control systems.
The journal of gene medicine 20020101
-
Sirolimus: has it gained from experience with older drugs?
Therapie 20020101
-
Sirolimus-eluting stents: the novel application of basic science to coronary artery disease.
Irish medical journal 20020101
-
[Problem with restenosis in connection to balloon angioplasty near to be solved].
Duodecim; laaketieteellinen aikakauskirja 20020101
-
Side-chain modified vitamin D analogs require activation of both PI 3-K and erk1,2 signal transduction pathways to induce differentiation of human promyelocytic leukemia cells.
Acta biochimica Polonica 20020101
-
Calcineurin inhibitor-induced chronic nephrotoxicity in liver transplant patients is reversible using rapamycin as the primary immunosuppressive agent.
Clinical transplantation 20020101
-
Four birds with one stone: RAPA as potential anticancer therapy.
Cancer biology & therapy 20020101
-
The macrolide immunosuppressants in dermatology: mechanisms of action.
European journal of dermatology : EJD 20020101
-
Rapamycin insensitivity in Schistosoma mansoni is not due to FKBP12 functionality.
Molecular and biochemical parasitology 20020101
-
Clinical experience with drug-eluting stents.
Reviews in cardiovascular medicine 20020101
-
What will be the impact of drug-eluting stents on hybrid coronary revascularization?
The heart surgery forum 20020101
-
Drug eluting stents: initial experiences.
Zeitschrift fur Kardiologie 20020101
-
Sirolimus-eluting stents: a review of experimental and clinical findings.
Zeitschrift fur Kardiologie 20020101
-
Perspectives of drug-eluting stents: the next revolution.
American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101
-
Super stents keep the blood flowing. New technology leaves damaged arteries wide open and unclogged.
Heart advisor 20020101
-
Sirolimus (rapamycin) for the treatment of steroid-refractory acute graft-versus-host disease.
Transplantation 20011227
-
Improving tolerability of immunosuppressive regimens.
Transplantation 20011227
-
Prospective monitoring of BK virus load after discontinuing sirolimus treatment in a renal transplant patient with BK virus nephropathy.
The Journal of infectious diseases 20011201
-
Regulation of Id2 gene expression by the type 1 IGF receptor and the insulin receptor substrate-1.
Endocrinology 20011201
-
Tailoring immunosuppressive therapy for renal transplant recipients.
Pediatric transplantation 20011201
-
The immunomodulatory drugs cyclosporin A, mycophenolate mofetil, and sirolimus (rapamycin) inhibit allergen-induced proliferation and IL-5 production by PBMCs from atopic asthmatic patients.
The Journal of allergy and clinical immunology 20011201
-
14-3-3 Proteins are essential for regulation of RTG3-dependent transcription in Saccharomyces cerevisiae.
Yeast (Chichester, England) 20011201
-
Cyclic stretch enhances the expression and activity of coronary endothelium-derived hyperpolarizing factor synthase.
Hypertension (Dallas, Tex. : 1979) 20011201
-
Single-point calibration for sirolimus quantification.
Therapeutic drug monitoring 20011201
-
Nephrotoxicity of immunosuppressive drugs: new insight and preventive strategies.
Current opinion in critical care 20011201
-
Insulin release and suppression by tacrolimus, rapamycin and cyclosporin A are through regulation of the ATP-sensitive potassium channel.
Diabetes, obesity & metabolism 20011201
-
Mechanisms of resistance to rapamycins.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20011201
-
[Mechanism in the cytoplasm accumulation of TOP binding factor].
The Japanese journal of antibiotics 20011201
-
Nerve growth factor uses Ras/ERK and phosphatidylinositol 3-kinase cascades to up-regulate the N-methyl-D-aspartate receptor 1 promoter.
The Journal of biological chemistry 20011130
-
Ribosomal protein S6 phosphorylation and function during late gestation liver development in the rat.
The Journal of biological chemistry 20011130
-
Phosphatidic acid-mediated mitogenic activation of mTOR signaling.
Science (New York, N.Y.) 20011130
-
American Heart Association 2001 scientific sessions: late-breaking science-drug-eluting stents.
Circulation 20011120
-
Brain-derived neurotrophic factor enhances neuronal translation by activating multiple initiation processes: comparison with the effects of insulin.
The Journal of biological chemistry 20011116
-
Antagonistic roles for CTLA-4 and the mammalian target of rapamycin in the regulation of clonal anergy: enhanced cell cycle progression promotes recall antigen responsiveness.
Journal of immunology (Baltimore, Md. : 1950) 20011115
-
Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells.
The EMBO journal 20011115
-
Phosphorylation and local presynaptic protein synthesis in calcium- and calcineurin-dependent induction of crayfish long-term facilitation.
Neuron 20011108
-
ErbB2-overexpressing human mammary carcinoma cells display an increased requirement for the phosphatidylinositol 3-kinase signaling pathway in anchorage-independent growth.
Oncogene 20011108
-
Mammalian TOR: a homeostatic ATP sensor.
Science (New York, N.Y.) 20011102
-
Rapamycin increases the cellular concentration of the BCL-2 protein and exerts an anti-apoptotic effect.
European journal of cancer (Oxford, England : 1990) 20011101
-
Rapamycin and less immunosuppressive analogs are toxic to Candida albicans and Cryptococcus neoformans via FKBP12-dependent inhibition of TOR.
Antimicrobial agents and chemotherapy 20011101
-
Macrolactam immunomodulators for topical treatment of inflammatory skin diseases.
Journal of the American Academy of Dermatology 20011101
-
The sirolimus coated stent: will the Achilles heel of interventional cardiology finally be cured?
European heart journal 20011101
-
Coronary restenosis elimination with a sirolimus eluting stent: first European human experience with 6-month angiographic and intravascular ultrasonic follow-up.
European heart journal 20011101
-
Hierarchical phosphorylation of the translation inhibitor 4E-BP1.
Genes & development 20011101
-
Targeting keratinocyte apoptosis in the treatment of atopic dermatitis and allergic contact dermatitis.
The Journal of allergy and clinical immunology 20011101
-
Noradrenaline-induced increase in protein synthesis in adult rat cardiomyocytes: involvement of only alpha1A-adrenoceptors.
Naunyn-Schmiedeberg's archives of pharmacology 20011101
-
Influence of hepatic impairment on everolimus pharmacokinetics: implications for dose adjustment.
Clinical pharmacology and therapeutics 20011101
-
Distinct regulatory mechanism for p70 S6 kinase beta from that for p70 S6 kinase alpha.
Genes to cells : devoted to molecular & cellular mechanisms 20011101
-
TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway.
Molecular cell 20011101
-
Estrogen and rapamycin effects on cell cycle progression in T47D breast cancer cells.
Breast cancer research and treatment 20011101
-
Sirolimus: a comprehensive review.
Expert opinion on pharmacotherapy 20011101
-
Mutagenesis of the rapamycin producer Streptomyces hygroscopicus FC904.
The Journal of antibiotics 20011101
-
Binding of the La autoantigen to the 5' untranslated region of a chimeric human translation elongation factor 1A reporter mRNA inhibits translation in vitro.
Biochimica et biophysica acta 20011031
-
Provocative effects of the immunosuppressants rapamycin, tacrolimus, and dexamethasone on pneumonitis in contrast to the anti- pneumonitis effects of mycophenolate mofetil.
Transplantation 20011027
-
Living the dream of no restenosis.
Circulation 20011023
-
Sustained suppression of neointimal proliferation by sirolimus-eluting stents: one-year angiographic and intravascular ultrasound follow-up.
Circulation 20011023
-
Rapamycin's resurrection: a new way to target the cancer cell cycle.
Journal of the National Cancer Institute 20011017
-
Rapamycin may prevent post-transplant lymphoma.
Journal of the National Cancer Institute 20011017
-
Pharmacological characterization of the putative cADP-ribose receptor.
The Biochemical journal 20011015
-
A WASp-VASP complex regulates actin polymerization at the plasma membrane.
The EMBO journal 20011015
-
Rapamycin: clinical results and future opportunities.
Transplantation 20011015
-
Effect of sirolimus on the metabolism of apoB100- containing lipoproteins in renal transplant patients.
Transplantation 20011015
-
Failure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation of rapamycin sensitive signaling.
Oncogene 20011011
-
Rapamycin impairs recovery from acute renal failure: role of cell-cycle arrest and apoptosis of tubular cells.
American journal of physiology. Renal physiology 20011001
-
Internal ribosome entry segment-mediated initiation of c-Myc protein synthesis following genotoxic stress.
The Biochemical journal 20011001
-
Rapamycin-sensitive phase of 3T3-L1 preadipocyte differentiation after clonal expansion.
Journal of cellular physiology 20011001
-
Target of rapamycin (TOR) inhibition in renal transplantation: Clinical uses in various populations. Introduction.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001
-
Cyclosporine elimination in the presence of TOR inhibitors: effects on renal function, acute rejection, and safety.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001
-
Safety and efficacy of TOR inhibitors and other immunosuppressive regimens in African-American renal transplant recipients.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001
-
Sirolimus and mycophenolate mofetil for calcineurin-free immunosuppression in renal transplant recipients.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001
-
Safety and efficacy of TOR inhibitors in pediatric renal transplant recipients.
American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001
-
From beach to bedside: history of the development of sirolimus.
Therapeutic drug monitoring 20011001
-
Use of rapamycin in a transplant patient who developed cyclosporin neurotoxicity.
Pediatric nephrology (Berlin, Germany) 20011001
-
Efficacy of SDZ RAD compared with CsA monotherapyand combined Rad/FTY720 treatment in a murine cardiac allotransplantation model.
Transplant immunology 20011001
-
Comparative study analyzing effects of sirolimus-cyclosporin and sirolimus-tacrolimus combinations on bile flow in the rat.
Digestive diseases and sciences 20011001
-
The mammalian target of rapamycin regulates C2C12 myogenesis via a kinase-independent mechanism.
The Journal of biological chemistry 20010928
-
Lysophosphatidic acid activates the 70-kDa S6 kinase via the lipoxygenase pathway.
Biochemical and biophysical research communications 20010928
-
Fluvastatin in combination with rad significantly reduces graft vascular disease in rat cardiac allografts.
Transplantation 20010927
-
Immune cells and immunosuppression in a porcine bronchial model of obliterative bronchiolitis.
Transplantation 20010927
-
Interstitial pneumonitis associated with sirolimus (rapamycin) therapy after liver transplantation.
Transplantation 20010927
-
Damaged microtubules can inactivate BCL-2 by means of the mTOR kinase.
Oncogene 20010927
-
Drug points: Premature osteonecrosis and sirolimus treatment in renal transplantation.
BMJ (Clinical research ed.) 20010922
-
Immunosuppressant rapamycin inhibits protein kinase C alpha and p38 mitogen-activated protein kinase leading to the inhibition of chondrogenesis.
European journal of pharmacology 20010921
-
An important role of CDK inhibitor p18(INK4c) in modulating antigen receptor-mediated T cell proliferation.
Journal of immunology (Baltimore, Md. : 1950) 20010915
-
Sirolimus: another cause of drug-induced interstitial pneumonitis.
Transplantation 20010915
-
Sirolimus: searching for its niche or a therapy that has come of age?
Transplantation 20010915
-
Sirolimus allows early cyclosporine withdrawal in renal transplantation resulting in improved renal function and lower blood pressure.
Transplantation 20010915
-
Characteristics of sirolimus-associated interstitial pneumonitis in renal transplant patients.
Transplantation 20010915
-
Sirolimus for rescue and primary immunosuppression in transplanted children receiving tacrolimus.
Transplantation 20010915
-
Interleukin-15 is the main mediator of lymphocyte proliferation in cultures mixed with human kidney tubular epithelial cells.
Transplantation 20010915
-
Selective inhibition of IL-2 gene expression by IL-2 antisense oligonucleotides blocks heart allograft rejection.
Transplantation 20010915
-
Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration.
Circulation research 20010914
-
Stent-based delivery of sirolimus reduces neointimal formation in a porcine coronary model.
Circulation 20010904
-
Bystander activation involving T lymphocytes in herpetic stromal keratitis.
Journal of immunology (Baltimore, Md. : 1950) 20010901
-
Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase inhibitor p27(kip1).
Blood 20010901
-
Efficacy of sirolimus (rapamycin) administered concomitantly with a subtherapeutic dose of cyclosporin in the treatment of severe psoriasis: a randomized controlled trial.
The British journal of dermatology 20010901
-
Sirolimus inhibition of lymphocyte proliferation is not antagonized by ciprofloxacin and other quinolone antibiotics.
Transplantation proceedings 20010901
-
Population pharmacokinetics of everolimus in de novo renal transplant patients: impact of ethnicity and comedications.
Clinical pharmacology and therapeutics 20010901
-
mTOR, a novel target in breast cancer: the effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer.
Endocrine-related cancer 20010901
-
Regeneration in avian hair cell epithelia: identification of intracellular signals required for S-phase entry.
The European journal of neuroscience 20010901
-
[Complications in kidney transplantation].
Presse medicale (Paris, France : 1983) 20010901
-
[Focus on Islets of Langerhans transplantation].
Presse medicale (Paris, France : 1983) 20010901
-
[mTOR and FTY 720 inhibitors].
Presse medicale (Paris, France : 1983) 20010901
-
[Immunosuppression, ongoing clinical trials].
Presse medicale (Paris, France : 1983) 20010901
-
Cholestasis and regulation of genes related to drug metabolism and biliary transport in rat liver following treatment with cyclosporine A and sirolimus (Rapamycin).
Pharmacology & toxicology 20010901
-
Everolimus. Novartis.
Current opinion in investigational drugs (London, England : 2000) 20010901
-
Cross-talk between the ERK and p70 S6 kinase (S6K) signaling pathways. MEK-dependent activation of S6K2 in cardiomyocytes.
The Journal of biological chemistry 20010831
-
Bench to bedside: the development of rapamycin and its application to stent restenosis.
Circulation 20010821
-
A maize insulin-like growth factor signals to a transduction pathway that regulates protein synthesis in maize.
The Biochemical journal 20010815
-
FK506 promotes adenosine release from endothelial cells via inhibition of adenosine kinase.
European journal of pharmacology 20010810
-
Ammonia regulates VID30 expression and Vid30p function shifts nitrogen metabolism toward glutamate formation especially when Saccharomyces cerevisiae is grown in low concentrations of ammonia.
The Journal of biological chemistry 20010803
-
Coexpression of CD4 and CD8alpha on rat T-cells in whole blood: a sensitive marker for monitoring T-cell immunosuppressive drugs.
Journal of immunological methods 20010801
-
HGF- and KGF-induced activation of PI-3K/p70 s6 kinase pathway in corneal epithelial cells: its relevance in wound healing.
Experimental eye research 20010801
-
Regulation of glycogen synthesis in human muscle cells.
Biochemical Society transactions 20010801
-
Orthotopic liver transplantation using low-dose tacrolimus and sirolimus.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20010801
-
In vitro immunosuppressive activity of tacrolimus dihydrodiol precursors obtained by chemical oxidation and identification of a new metabolite of SDZ-RAD by electrospray and electrospray-linked scan mass spectrometry.
Journal of mass spectrometry : JMS 20010801
-
Staurosporine inhibits phosphorylation of translational regulators linked to mTOR.
Cell death and differentiation 20010801
-
Natural products as immunosuppressive agents.
Natural product reports 20010801
-
Advances in systemic therapy of small cell cancer of the lung.
Expert review of anticancer therapy 20010801
-
Cdc25A phosphatase suppresses apoptosis induced by serum deprivation.
Oncogene 20010727
-
Sirolimus-associated eyelid edema in kidney transplant recipients.
Transplantation 20010715
-
Phosphorylation regulates the interaction between Gln3p and the nuclear import factor Srp1p.
The Journal of biological chemistry 20010706
-
Rapamycin blocks sexual development in fission yeast through inhibition of the cellular function of an FKBP12 homolog.
The Journal of biological chemistry 20010706
-
Flow cytometric quantitation of calcium-dependent and -independent mitogen-stimulation of T cell functions in whole blood: inhibition by immunosuppressive drugs in vitro.
Journal of immunological methods 20010701
-
Angiotensin II regulates phosphorylation of translation elongation factor-2 in cardiac myocytes.
American journal of physiology. Heart and circulatory physiology 20010701
-
Rapamycin induces apoptosis in monocyte- and CD34-derived dendritic cells but not in monocytes and macrophages.
Blood 20010701
-
Combined effect of cyclosporine and sirolimus on improving the longevity of recombinant adenovirus-mediated transgene expression in the retina.
Archives of ophthalmology (Chicago, Ill. : 1960) 20010701
-
Cell cycle protein expression in vascular smooth muscle cells in vitro and in vivo is regulated through phosphatidylinositol 3-kinase and mammalian target of rapamycin.
Arteriosclerosis, thrombosis, and vascular biology 20010701
-
Median effect analysis of efficacy versus adverse effects of immunosuppressants.
Clinical pharmacology and therapeutics 20010701
-
Sirolimus, but not the structurally related RAD (everolimus), enhances the negative effects of cyclosporine on mitochondrial metabolism in the rat brain.
British journal of pharmacology 20010701
-
The effect of different immunosuppressants on alloantigen dependent and independent factors involved in the development of chronic rejection in an animal model.
Annals of the Royal College of Surgeons of England 20010701
-
New developments in the prophylaxis and treatment of graft versus host disease.
Expert opinion on pharmacotherapy 20010701
-
Cell cycle and cell migration: new pieces to the puzzle.
Circulation 20010619
-
Role for p27(Kip1) in Vascular Smooth Muscle Cell Migration.
Circulation 20010619
-
Activation loop sequences confer substrate specificity to phosphoinositide 3-kinase alpha (PI3Kalpha ). Functions of lipid kinase-deficient PI3Kalpha in signaling.
The Journal of biological chemistry 20010615
-
Signal transduction pathways involved in phosphorylation and activation of p70S6K following exposure to UVA irradiation.
The Journal of biological chemistry 20010615
-
Sirolimus rescue therapy for refractory rejection in renal transplantation.
Transplantation 20010615
-
Effect of low dose cyclosporine and sirolimus on hepatic drug metabolism in the rat1.
Transplantation 20010615
-
Vascular and cellular mechanisms of chronic renal allograft dysfunction.
Transplantation 20010615
-
Exploring treatment options in renal transplantation: the problems of chronic allograft dysfunction and drug-related nephrotoxicity.
Transplantation 20010615
-
Potential therapeutic interventions to avoid or treat chronic allograft dysfunction.
Transplantation 20010615
-
Regulation of the levels of small heat-shock proteins during differentiation of C2C12 cells.
Experimental cell research 20010610
-
Coupled gating between cardiac calcium release channels (ryanodine receptors).
Circulation research 20010608
-
Metabolism of sirolimus and its derivative everolimus by cytochrome P450 3A4: insights from docking, molecular dynamics, and quantum chemical calculations.
Journal of medicinal chemistry 20010607
-
A high-capacity quantitative mouse model of drug-mediated immunosuppression based on rejection of an allogeneic subcutaneous tumor.
The Journal of pharmacology and experimental therapeutics 20010601
-
Cell proliferation through forced engagement of c-Kit and Flt-3.
Blood 20010601
-
Insulin-like growth factor-I augments prolactin and inhibits growth hormone release through distinct as well as overlapping cellular signaling pathways.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010601
-
Effect of p27 deficiency and rapamycin on intimal hyperplasia: in vivo and in vitro studies using a p27 knockout mouse model.
Laboratory investigation; a journal of technical methods and pathology 20010601
-
Biochemical correlates of mTOR inhibition by the rapamycin ester CCI-779 and tumor growth inhibition.
Clinical cancer research : an official journal of the American Association for Cancer Research 20010601
-
Simultaneous simple and fast quantification of three major immunosuppressants by liquid chromatography--tandem mass-spectrometry.
Clinical biochemistry 20010601
-
mTOR inhibitors: an overview.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20010601
-
Sirolimus improves the two-year outcome of renal allografts in African-American patients.
Transplant international : official journal of the European Society for Organ Transplantation 20010601
-
RAD in de novo renal transplantation: comparison of three doses on the incidence and severity of acute rejection.
Transplantation 20010527
-
FRAP-p70s6K signaling is required for pancreatic cancer cell proliferation.
The Journal of surgical research 20010515
-
A calcineurin antagonist-free induction strategy for immunosuppression in cadaveric kidney transplant recipients at risk for delayed graft function.
Transplantation 20010515
-
New drug development in non-Hodgkin lymphomas.
Current oncology reports 20010501
-
Up-regulation of cell surface sodium channels by cyclosporin A, FK506, and rapamycin in adrenal chromaffin cells.
The Journal of pharmacology and experimental therapeutics 20010501
-
Sanglifehrin A, a novel cyclophilin-binding immunosuppressant, inhibits IL-2-dependent T cell proliferation at the G1 phase of the cell cycle.
Journal of immunology (Baltimore, Md. : 1950) 20010501
-
Pharmacokinetic interactions augment toxicities of sirolimus/cyclosporine combinations.
Journal of the American Society of Nephrology : JASN 20010501
-
Flow-induced DNA synthesis requires signaling to a translational control pathway.
The Journal of surgical research 20010501
-
Endotoxin (LPS) stimulates 4E-BP1/PHAS-I phosphorylation in macrophages.
The Journal of surgical research 20010501
-
Dyslipidemia during sirolimus therapy in liver transplant recipients occurs with concomitant cyclosporine but not tacrolimus.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20010501
-
Induction of differentiation of human myeloid leukemia cells by immunosuppressant macrolides (rapamycin and FK506) and calcium/calmodulin-dependent kinase inhibitors.
Experimental hematology 20010501
-
Overview of side effects of immunosuppressive therapy.
Transplantation proceedings 20010501
-
Assessment of mechanisms of action of immunosuppressive drugs using novel whole blood assays.
Transplantation proceedings 20010501
-
Sirolimus and erythromycin interaction: two cases.
Transplantation proceedings 20010501
-
Overview of clinical trials with new agents.
Transplantation proceedings 20010501
-
Phase III trial of Rapamune versus placebo in primary renal allograft recipients.
Transplantation proceedings 20010501
-
RAD reduces compensatory renal graft hypertrophy in a rat model of chronic rejection.
Transplantation proceedings 20010501
-
FTY-720 is efficacious in monkey kidney transplantation.
Transplantation proceedings 20010501
-
Adjunctive rapamycin and CsA treatment inhibits monocyte/macrophage associated cytokines/chemokines in sensitized cardiac graft recipients.
Transplantation 20010427
-
p53/p21(CIP1) cooperate in enforcing rapamycin-induced G(1) arrest and determine the cellular response to rapamycin.
Cancer research 20010415
-
Akt mediates insulin induction of glucose uptake and up-regulation of GLUT4 gene expression in brown adipocytes.
FEBS letters 20010413
-
Rapamycin-insensitive regulation of 4e-BP1 in regenerating rat liver.
The Journal of biological chemistry 20010406
-
Regulation of translation initiation by FRAP/mTOR.
Genes & development 20010401
-
Liver transplantation using sirolimus and minimal corticosteroids (3-day taper).
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20010401
-
Prevention of neointimal proliferation by immunosuppression in synthetic vascular grafts.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20010401
-
Review: uveitis and immunosuppressive drugs.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20010401
-
Signalling pathways regulating the dephosphorylation of Ser729 in the hydrophobic domain of protein kinase Cepsilon upon cell passage.
The Journal of biological chemistry 20010330
-
The TOR kinases link nutrient sensing to cell growth.
The Journal of biological chemistry 20010330
-
The cell survival signal Akt is differentially activated by PDGF-BB, EGF, and FGF-2 in osteoblastic cells.
Journal of cellular biochemistry 20010326
-
[Prevention of instant restenosis after coronary angioplasty by implantation of rapamycin-coated stents].
Ugeskrift for laeger 20010319
-
The fission yeast TOR homolog, tor1+, is required for the response to starvation and other stresses via a conserved serine.
The Journal of biological chemistry 20010309
-
Regulation of APG14 expression by the GATA-type transcription factor Gln3p.
The Journal of biological chemistry 20010302
-
Involvement of both phosphatidylinositol 3-kinase and p44/p42 mitogen-activated protein kinase pathways in the short-term regulation of pyruvate kinase L by insulin.
Endocrinology 20010301
-
Uncoupling p70(s6) kinase activation and proliferation: rapamycin-resistant proliferation of human CD8(+) T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 20010301
-
New immunosuppressive drugs: an update.
Current opinion in urology 20010301
-
Failure of GPI compounds to display neurotrophic activity in vitro and in vivo.
European journal of pharmacology 20010301
-
Use of sirolimus in kidney transplantation.
Progress in transplantation (Aliso Viejo, Calif.) 20010301
-
Deletion of rapQONML from the rapamycin gene cluster of Streptomyces hygroscopicus gives production of the 16-O-desmethyl-27-desmethoxy analog.
The Journal of antibiotics 20010301
-
Treatment of transplant rejection: are the traditional immunosuppressants good enough?
Current opinion in investigational drugs (London, England : 2000) 20010301
-
Translation initiation of the insulin-like growth factor I receptor mRNA is mediated by an internal ribosome entry site.
The Journal of biological chemistry 20010223
-
Antitumor activity of the rapamycin analog CCI-779 in human primitive neuroectodermal tumor/medulloblastoma models as single agent and in combination chemotherapy.
Cancer research 20010215
-
Overexpression of FK506-binding protein FKBP12.6 in cardiomyocytes reduces ryanodine receptor-mediated Ca(2+) leak from the sarcoplasmic reticulum and increases contractility.
Circulation research 20010202
-
Impaired phosphate handling of renal allografts is aggravated under rapamycin-based immunosuppression.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010201
-
The rapamycin sensitivity of human T-cell leukaemia virus type I-induced T-cell proliferation is mediated independently of the polypyrimidine motifs in the 5' long terminal repeat.
The Journal of general virology 20010201
-
Solubilization of rapamycin.
International journal of pharmaceutics 20010201
-
Sirolimus interferes with the innate response to bacterial products in human whole blood by attenuation of IL-10 production.
Scandinavian journal of immunology 20010201
-
The flightless I protein colocalizes with actin- and microtubule-based structures in motile Swiss 3T3 fibroblasts: evidence for the involvement of PI 3-kinase and Ras-related small GTPases.
Journal of cell science 20010201
-
Stent coatings.
The Journal of invasive cardiology 20010201
-
40-O-(2-hydroxyethyl)-rapamycin attenuates pulmonary arterial hypertension and neointimal formation in rats.
American journal of respiratory and critical care medicine 20010201
-
[Effect of rapamycin on cytoplasmic accumulation of hetero nuclear ribonucleoprotein C-like unwinding protein 2].
The Japanese journal of antibiotics 20010201
-
A worldwide, phase III, randomized, controlled, safety and efficacy study of a sirolimus/cyclosporine regimen for prevention of acute rejection in recipients of primary mismatched renal allografts.
Transplantation 20010127
-
Frap-dependent serine phosphorylation of IRS-1 inhibits IRS-1 tyrosine phosphorylation.
Biochemical and biophysical research communications 20010126
-
[Rapamycin: a new immunosuppressive agent capable of inhibiting chronic rejection?].
Casopis lekaru ceskych 20010119
-
Lack of neointimal proliferation after implantation of sirolimus-coated stents in human coronary arteries: a quantitative coronary angiography and three-dimensional intravascular ultrasound study.
Circulation 20010116
-
Insulin inhibits glucocorticoid-stimulated L-type 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene expression by activation of the c-Jun N-terminal kinase pathway.
The Biochemical journal 20010115
-
Serotonin activates S6 kinase in a rapamycin-sensitive manner in Aplysia synaptosomes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20010115
-
Intracellular signals that control cell proliferation in mammalian balance epithelia: key roles for phosphatidylinositol-3 kinase, mammalian target of rapamycin, and S6 kinases in preference to calcium, protein kinase C, and mitogen-activated protein kinase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20010115
-
Pharmacokinetics and tolerability of 40-0-[2-hydroxyethyl]rapamycin in de novo liver transplant recipients.
Transplantation 20010115
-
Regulation of glycogen synthesis by amino acids in cultured human muscle cells.
The Journal of biological chemistry 20010112
-
Effects of immunosuppressants on receptor activator of NF-kappaB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells.
Biochemical and biophysical research communications 20010112
-
Relative resistance in the development of T cell anergy in CD4+ T cells from simian immunodeficiency virus disease-resistant sooty mangabeys.
Journal of immunology (Baltimore, Md. : 1950) 20010101
-
Counter-regulation of cytolytic activity and cytokine production in HIV-1-specific murine CD8+ cytotoxic T lymphocytes by free antigenic peptide.
International immunology 20010101
-
Rapamycin in transplantation: a review of the evidence.
Kidney international 20010101
-
Phosphatidylinositol-3,4,5-trisphosphate is required for insulin-like growth factor 1-mediated survival of 3T3-L1 preadipocytes.
Endocrinology 20010101
-
Induction of the C/EBP homologous protein (CHOP) by amino acid deprivation requires insulin-like growth factor I, phosphatidylinositol 3-kinase, and mammalian target of rapamycin signaling.
Endocrinology 20010101
-
Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation.
Diabetes 20010101
-
Immunosuppressant use without bone loss--implications for bone loss after transplantation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010101
-
Pharmacokinetic interaction between single oral doses of diltiazem and sirolimus in healthy volunteers.
Clinical pharmacology and therapeutics 20010101
-
Longitudinal assessment of everolimus in de novo renal transplant recipients over the first post-transplant year: pharmacokinetics, exposure-response relationships, and influence on cyclosporine.
Clinical pharmacology and therapeutics 20010101
-
Sirolimus: a new promising immunosuppressive drug. Towards a rationale for its use in renal transplantation.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010101
-
Evidence that phosphorylation of human Upfl protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive PI 3-kinase-related kinase signaling pathway.
RNA (New York, N.Y.) 20010101
-
Immunosuppressive drugs in paediatric liver transplantation.
Paediatric drugs 20010101
-
Rapamycin for GVHD prophylaxis--potential for severe myelotoxicity.
Bone marrow transplantation 20010101
-
Involvement of p70 S6 kinase in bone morphogenetic protein signaling: vascular endothelial growth factor synthesis by bone morphogenetic protein-4 in osteoblasts.
Journal of cellular biochemistry 20010101
-
Strategies for induction of clinical tolerance.
Transplantation proceedings 20010101
-
Expression of MHC class II antigen is essential in tolerance induction by donor bone marrow cell in antilymphocyte serum-treated and rapamycin-treated mice.
Transplantation proceedings 20010101
-
Induction of peripheral tolerance by posttransplant infusion of donor splenocytes.
Transplantation proceedings 20010101
-
Addition of rapamycin to cyclosporine-prednisone based immunosuppression reduces the clinical risk of pretransplant anti-HLA antibody.
Transplantation proceedings 20010101
-
Temporary treatment with sirolimus and low-trough cyclosporine prevents acute islet allograft rejection, and combination with starch-conjugated deferoxamine promotes islet engraftment in the preclinical pig model.
Transplantation proceedings 20010101
-
Comparison of the in vitro metabolism of the macrolide immunosuppressants sirolimus and RAD.
Transplantation proceedings 20010101
-
Rapamycin reduces expression of fibrosis-associated genes in an experimental model of renal ischaemia reperfusion injury.
Transplantation proceedings 20010101
-
Donor pretreatment of grafts from marginal donors improves long-term graft outcome.
Transplantation proceedings 20010101
-
Sirolimus is effective for prevention of acute rejection in primary mismatched renal allograft recipients.
Transplantation proceedings 20010101
-
Sirolimus rescue therapy for refractory rejection in renal transplant recipients.
Transplantation proceedings 20010101
-
Effect of rapamycin and FK506 on mesangial cell proliferation.
Transplantation proceedings 20010101
-
Sirolimus-tacrolimus combination for combined kidney-pancreas transplantation: effect on renal function.
Transplantation proceedings 20010101
-
Sirolimus does not potentiate indices of chronic cyclosporin nephrotoxicity.
Transplantation proceedings 20010101
-
A single-center open label randomized trial of the safety and efficacy of the use of sirolimus versus azathioprine in one-haplotype living related kidney transplant recipients-preliminary results.
Transplantation proceedings 20010101
-
Cyclosporine and tacrolimus alter renin-angiotesin system in mouse medullary-thick ascending limb cultured cells.
Transplantation proceedings 20010101
-
Rescue therapy: a role for sirolimus in lung and heart transplant recipients.
Transplantation proceedings 20010101
-
Pharmacokinetic interactions between sirolimus and cyclosporine exacerbate renal dysfunction.
Transplantation proceedings 20010101
-
Fast quantification method for sirolimus and its major metabolites.
Transplantation proceedings 20010101
-
Impact of sirolimus on renal transplant outcomes in African Americans.
Transplantation proceedings 20010101
-
Sirolimus permits steroid withdrawal from a cyclosporine regimen.
Transplantation proceedings 20010101
-
Therapeutic drug monitoring of sirolimus for optimal renal transplant outcomes.
Transplantation proceedings 20010101
-
De novo use of low-dose tacrolimus and sirolimus in liver transplantation.
Transplantation proceedings 20010101
-
Sirolimus (rapamycin)-based rescue treatment following chronic rejection after liver transplantation.
Transplantation proceedings 20010101
-
Rapamycin blocks IL-2-driven T cell cycle progression while preserving T cell survival.
Blood cells, molecules & diseases 20010101
-
Influence of cyclosporin, tacrolimus and rapamycin on renal function and arterial hypertension after renal transplantation.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010101
-
Rapamycin reduces hybridoma cell death and enhances monoclonal antibody production.
Biotechnology and bioengineering 20010101
-
High-throughput semi-automated 96-well liquid/liquid extraction and liquid chromatography/mass spectrometric analysis of everolimus (RAD 001) and cyclosporin a (CsA) in whole blood.
Rapid communications in mass spectrometry : RCM 20010101
-
Protein tyrosine kinase-dependent regulation of adenylate cyclase and phosphatidylinositol 3-kinase activates the expression of glial fibrillary acidic protein upon induction of differentiation in rat c6 glioma.
Cell biology international 20010101
-
Methods and assays to investigate nuclear export.
Current topics in microbiology and immunology 20010101
-
HPLC assay with ultraviolet detection for therapeutic drug monitoring of sirolimus.
Clinical chemistry 20010101
-
A new vascularized adrenal transplantation model in the rat.
Microsurgery 20010101
-
Adverse gastrointestinal effects of mycophenolate mofetil: aetiology, incidence and management.
Drug safety 20010101
-
Clinical pharmacokinetics of sirolimus.
Clinical pharmacokinetics 20010101
-
Control of translation by the target of rapamycin proteins.
Progress in molecular and subcellular biology 20010101
-
Regulation of protein synthesis by insulin through IRS-1.
Progress in molecular and subcellular biology 20010101
-
The evolving role of tor inhibitors for individualizing posttransplant immunosuppression.
Transplantation proceedings 20010101
-
Abbreviated cyclosporine pharmacokinetic profiling in clinical renal transplantation: from principles to practice.
Transplantation proceedings 20010101
-
The role of Certican (everolimus, rad) in the many pathways of chronic rejection.
Transplantation proceedings 20010101
-
Rapamycin reduces rejection in heart transplant recipients.
Transplantation proceedings 20010101
-
Sirolimus and low-dose tacrolimus with antibody induction in kidney transplantation: preliminary results of a pilot study.
Transplantation proceedings 20010101
-
Low-dose sirolimus and tacrolimus in kidney transplantation: first results of a single-center experience.
Transplantation proceedings 20010101
-
Low-dose immunosuppression with FK 506 and sirolimus after liver transplantation: 1-year results.
Transplantation proceedings 20010101
-
A pilot study of steroid withdrawal from kidney transplant recipients on sirolimus-cyclosporine a combination therapy.
Transplantation proceedings 20010101
-
Conversion to rapamycin in renal allograft recipients with biopsy-proven calcineurin inhibitor-induced nephrotoxicity.
Transplantation proceedings 20010101
-
De novo hemolytic uremic syndrome after kidney transplantation in patients treated with cyclosporine a sirolimus combination.
Transplantation proceedings 20010101
-
Effect of ERL080A, RAD, and Neoral on hamster-to-rat heart xenograft survival.
Transplantation proceedings 20010101
-
Stent development and local drug delivery.
British medical bulletin 20010101
-
[New developments in immunosuppressive therapy].
Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress 20010101
-
Resistance to rapamycin: a novel anticancer drug.
Cancer metastasis reviews 20010101
-
[Toward an evidence-based immunosuppression].
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20010101
-
Secondary metabolism in simulated microgravity.
Chemical record (New York, N.Y.) 20010101
-
Anaerobic growth of Saccharomyces cerevisiae alleviates the lethal effect of phosphotyrosyl phosphatase activators depletion.
Acta biochimica Polonica 20010101
-
The drug-eluting stent: is it the Holy Grail?
Reviews in cardiovascular medicine 20010101
-
Conversion to rapamycin immunosuppression in renal transplant recipients: report of an initial experience.
Transplantation 20001027
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors.
The Biochemical journal 20001001
-
Endothelin-1 as a protective factor against beta-adrenergic agonist-induced apoptosis in cardiac myocytes.
Journal of the American College of Cardiology 20001001
-
Stem cell factor/c-kit up-regulates cyclin D3 and promotes cell cycle progression via the phosphoinositide 3-kinase/p70 S6 kinase pathway in spermatogonia.
The Journal of biological chemistry 20000818
-
Antifungal rapamycin analogues with reduced immunosuppressive activity.
Bioorganic & medicinal chemistry letters 20000703
-
Sirolimus: a new agent for prevention of renal allograft rejection.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20000301
-
Sirolimus in pediatric gastrointestinal transplantation: the use of sirolimus for pediatric transplant patients with tacrolimus-related cardiomyopathy.
Pediatric transplantation 20000201
-
Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis.
Gastroenterology 19991101
-
A phase I study of a 4-week course of SDZ-RAD (RAD) quiescent cyclosporine-prednisone-treated renal transplant recipients.
Transplantation 19991027
-
Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug action.
Clinical microbiology reviews 19991001
-
Cellular stress in xenopus kidney cells enhances the phosphorylation of eukaryotic translation initiation factor (eIF)4E and the association of eIF4F with poly(A)-binding protein.
The Biochemical journal 19990915
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Neuronal survival activity of s100betabeta is enhanced by calcineurin inhibitors and requires activation of NF-kappaB.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19990901
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p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes.
Molecular and cellular biology 19990701
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Rapamycin inhibits didemnin B-induced apoptosis in human HL-60 cells: evidence for the possible involvement of FK506-binding protein 25.
Immunology and cell biology 19990601
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Systemic toxicity following administration of sirolimus (formerly rapamycin) for psoriasis: association of capillary leak syndrome with apoptosis of lesional lymphocytes.
Archives of dermatology 19990501
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Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with cyclosporine. Sirolimus European Renal Transplant Study Group.
Transplantation 19990415
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The FKBP12-rapamycin-binding domain is required for FKBP12-rapamycin-associated protein kinase activity and G1 progression.
The Journal of biological chemistry 19990212
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Immunophilins: beyond immunosuppression.
Journal of medicinal chemistry 19981217
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Regulation of System A amino acid transport in L6 rat skeletal muscle cells by insulin, chemical and hyperthermic stress.
FEBS letters 19981211
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Expression and regulation of neuronal apoptosis inhibitory protein during adipocyte differentiation.
Diabetes 19981201
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Ascomycin macrolactam derivative SDZ ASM 981 inhibits the release of granule-associated mediators and of newly synthesized cytokines in RBL 2H3 mast cells in an immunophilin-dependent manner.
Archives of dermatological research 19980901
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Chemical modification of rapamycin: the discovery of SDZ RAD.
Transplantation proceedings 19980801
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Protective effects of FK506 against glutamate-induced neurotoxicity in retinal cell culture.
Investigative ophthalmology & visual science 19980601
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Antifungal activities of rapamycin and its derivatives, prolylrapamycin, 32-desmethylrapamycin, and 32-desmethoxyrapamycin.
The Journal of antibiotics 19980501
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Radiosensitization of human tumor cells by the phosphatidylinositol3-kinase inhibitors wortmannin and LY294002 correlates with inhibition of DNA-dependent protein kinase and prolonged G2-M delay.
Clinical cancer research : an official journal of the American Association for Cancer Research 19970701
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Rapamycin (sirolimus) inhibits proliferating cell nuclear antigen expression and blocks cell cycle in the G1 phase in human keratinocyte stem cells.
The Journal of clinical investigation 19970501
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Novel anti-Pneumocystis carinii effects of the immunosuppressant mycophenolate mofetil in contrast to provocative effects of tacrolimus, sirolimus, and dexamethasone.
The Journal of infectious diseases 19970401
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Sirolimus, a new, potent immunosuppressive agent.
Pharmacotherapy 19970101
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Rapamycin stimulates viral protein synthesis and augments the shutoff of host protein synthesis upon picornavirus infection.
Journal of virology 19961201
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Comparison of acute rapamycin nephrotoxicity with cyclosporine and FK506.
Kidney international 19961001
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Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation.
The EMBO journal 19960201
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Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.
Molecular pharmacology 19960201
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Rapamycin inhibits the in vitro release of soluble interleukin-2 receptor by activated peripheral blood mononuclear cells (PBMC) independently of the mode of activation.
International journal of immunopharmacology 19950701
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Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue.
Proceedings of the National Academy of Sciences of the United States of America 19950523
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Rapamycin-FKBP inhibits cell cycle regulators of proliferation in vascular smooth muscle cells.
Circulation research 19950301
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Nephrotoxicity of cyclosporin A and FK506: inhibition of calcineurin phosphatase.
Renal physiology and biochemistry 19950101
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RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex.
Proceedings of the National Academy of Sciences of the United States of America 19941220
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Nephrotoxicity of immunosuppressants in rats: comparison of macrolides with cyclosporin.
Experimental nephrology 19940101
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Rapamycin-FKBP12 blocks proliferation, induces differentiation, and inhibits cdc2 kinase activity in a myogenic cell line.
The Journal of biological chemistry 19931205
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Rapamycin blocks cell cycle progression of activated T cells prior to events characteristic of the middle to late G1 phase of the cycle.
Journal of cellular physiology 19930101
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Immunosuppressants FK506 and rapamycin function as reversal agents of the multidrug resistance phenotype.
Blood 19920915
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Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase.
Nature 19920702
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Rapamycin and FK506 differentially inhibit mast cell cytokine production and cytokine-induced proliferation and act as reciprocal antagonists.
The Journal of pharmacology and experimental therapeutics 19920601
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Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A.
Proceedings of the National Academy of Sciences of the United States of America 19920501
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Effects of steroids and immunosuppressive drugs on endotoxin-uveitis in rabbits.
Journal of ocular pharmacology 19920101
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Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes.
Cell 19910823
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The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation.
European journal of immunology 19910201
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Calcineurin primes immature gonadotropin-releasing hormone-secreting neuroendocrine cells for migration.
Molecular endocrinology (Baltimore, Md.)
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Chronic inhibition of the mTORC1/S6K1 pathway increases insulin-induced PI3K activity but inhibits Akt2 and glucose transport stimulation in 3T3-L1 adipocytes.
Molecular endocrinology (Baltimore, Md.)