53671-71-9 | Ici 89406

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$258.00	$180.00
250mg	95%	in stock	$572.00	$400.00

Description

• Catalog Number: AB74736
• Chemical Name: Ici 89406
• CAS Number: 53671-71-9
• Molecular Formula: C19H22N4O3
• Molecular Weight: 354.4030
• MDL Number: MFCD00673934
• SMILES: N#Cc1ccccc1OCC(CNCCNC(=O)Nc1ccccc1)O

Computed Properties

• Complexity: 459
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 26
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 9
• Undefined Atom Stereocenter Count: 1
• XLogP3: 1.1

Literature

• Preclinical evaluation of an 18F-labelled beta1-adrenoceptor selective radioligand based on ICI 89,406.

  Nuclear medicine and biology 20100501

• Are [O-methyl-11C]derivatives of ICI 89,406 beta1-adrenoceptor selective radioligands suitable for PET?

  European journal of nuclear medicine and molecular imaging 20080101

• Different changes of plasma membrane beta-adrenoceptors in rat heart after chronic administration of propranolol, atenolol and bevantolol.

  Life sciences 20070712

• Design of new beta1-selective adrenoceptor ligands as potential radioligands for in vivo imaging.

  Bioorganic & medicinal chemistry 20030805

• [High non-specific binding of the beta(1) -selective radioligand 2-(125)I-ICI-H].

  Nuklearmedizin. Nuclear medicine 20030801

• Evaluation of beta-adrenergic receptor subtypes in the human prostate cancer cell line-LNCaP.

  Biochemical pharmacology 20030501

• Molecular pharmacology of the beta-adrenergic receptor on THP-1 cells.

  International journal of immunopharmacology 19930201