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In vitro toxicological evaluation of NCS-382, a high-affinity antagonist of γ-hydroxybutyrate (GHB) binding.
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Cytochrome P450 inhibition potential of new psychoactive substances of the tryptamine class.
Toxicology letters 20160122
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Investigation of a novel series of 2-hydroxyisoquinoline-1,3(2H,4H)-diones as human immunodeficiency virus type 1 integrase inhibitors.
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Investigations on the metabolic stability of cytosolic phospholipase A2α inhibitors with 1-indolylpropan-2-one structure.
Chemico-biological interactions 20131125
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Interactions of sesquiterpenes zederone and germacrone with the human cytochrome P450 system.
Toxicology in vitro : an international journal published in association with BIBRA 20130901
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Direct and metabolism-dependent cytochrome P450 inhibition assays for evaluating drug-drug interactions.
Journal of applied toxicology : JAT 20130201
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A novel selective LSD1/KDM1A inhibitor epigenetically blocks herpes simplex virus lytic replication and reactivation from latency.
mBio 20130101
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In silico and intuitive predictions of CYP46A1 inhibition by marketed drugs with subsequent enzyme crystallization in complex with fluvoxamine.
Molecular pharmacology 20121101
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Risperidone attenuates the increase of extracellular nitric oxide and glutamate levels in serotonin syndrome animal models.
Neuroscience letters 20121018
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Oncoepigenomics: making histone lysine methylation count.
European journal of medicinal chemistry 20121001
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Evaluation of inhibition selectivity for human cytochrome P450 2A enzymes.
Drug metabolism and disposition: the biological fate of chemicals 20120901
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Lysine-specific demethylase 1 (LSD1/KDM1A/AOF2/BHC110) is expressed and is an epigenetic drug target in chondrosarcoma, Ewing's sarcoma, osteosarcoma, and rhabdomyosarcoma.
Human pathology 20120801
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Tranylcypromine and bupropion combination therapy in treatment-resistant major depression: a report of 2 cases.
Journal of clinical psychopharmacology 20120801
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Novel colorimetric assay of LSD1 activity using gold nanoparticles.
The Analyst 20120607
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[Effect of monoamine oxidase inhibitor on the differentiation of malignant glioma cell].
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20120601
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Anxiety-like behavior and cognitive flexibility in adult rats perinatally exposed to increased serotonin concentrations.
Behavioural brain research 20120421
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Effects of amitriptyline, fluoxetine, tranylcypromine and venlafaxine on rat vascular smooth muscle in vitro--the role of the endothelium.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20120401
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FAD-dependent lysine-specific demethylase-1 regulates cellular energy expenditure.
Nature communications 20120327
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Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia.
Nature medicine 20120311
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The effects of chronic administration of tranylcypromine and rimonabant on behaviour and protein expression in brain regions of the rat.
Pharmacology, biochemistry, and behavior 20120101
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Knockdown of menin affects pre-mRNA processing and promoter fidelity at the interferon-gamma inducible IRF1 gene.
Epigenetics & chromatin 20120101
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Role of androgen receptor and associated lysine-demethylase coregulators, LSD1 and JMJD2A, in localized and advanced human bladder cancer.
Molecular carcinogenesis 20111201
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The seminoma cell line TCam-2 is sensitive to HDAC inhibitor depsipeptide but tolerates various other chemotherapeutic drugs and loss of NANOG expression.
Genes, chromosomes & cancer 20111201
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Lysine-specific demethylase 1 is highly expressed in solitary fibrous tumors, synovial sarcomas, rhabdomyosarcomas, desmoplastic small round cell tumors, and malignant peripheral nerve sheath tumors.
Human pathology 20111101
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Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells.
Cell research 20111001
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Effects of CYP inhibitors on precocene I metabolism and toxicity in rat liver slices.
Chemico-biological interactions 20110905
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Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors.
Neuro-oncology 20110801
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The effects of the perinatal treatment with 5-hydroxytryptophan or tranylcypromine on the peripheral and central serotonin homeostasis in adult rats.
Neurochemistry international 20110801
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Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1).
PLoS pathogens 20110801
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Mechanism-based inhibition of cytochrome P450 (CYP)2A6 by chalepensin in recombinant systems, in human liver microsomes and in mice in vivo.
British journal of pharmacology 20110701
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Enantioselective synthesis of tranylcypromine analogues as lysine demethylase (LSD1) inhibitors.
Bioorganic & medicinal chemistry 20110615
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Thyroid hormone suppression of β-amyloid precursor protein gene expression in the brain involves multiple epigenetic regulatory events.
Molecular and cellular endocrinology 20110606
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Serotonergic mechanism underlying tranylcypromine enhancement of nicotine self-administration.
Synapse (New York, N.Y.) 20110601
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Simple, direct, and informative method for the assessment of CYP2C19 enzyme inactivation kinetics.
Drug metabolism and disposition: the biological fate of chemicals 20110301
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Chemical inhibitors of cytochrome P450 isoforms in human liver microsomes: a re-evaluation of P450 isoform selectivity.
European journal of drug metabolism and pharmacokinetics 20110301
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Advances pertaining to the pharmacology and interactions of irreversible nonselective monoamine oxidase inhibitors.
Journal of clinical psychopharmacology 20110201
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Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist.
Drug metabolism and disposition: the biological fate of chemicals 20110101
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The monoamine oxidase (MAO) inhibitor tranylcypromine enhances nicotine self-administration in rats through a mechanism independent of MAO inhibition.
Neuropharmacology 20110101
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Chemical biology of lysine demethylases.
Current chemical genomics 20110101
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Generation of Induced Pluripotent Stem (iPS) Cells by Nuclear Reprogramming.
Stem cells international 20110101
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On the formation and nature of the imidazoline I2 binding site on human monoamine oxidase-B.
Pharmacological research 20101201
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Potentiation of ligand binding through cooperative effects in monoamine oxidase B.
The Journal of biological chemistry 20101119
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Serotonin syndrome with severe hyperthermia after ingestion of tranylcypromine combined with serotonin reuptake inhibitors and tyramine-rich food in a case of suicide.
Pharmacopsychiatry 20101101
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Structural basis of drug binding to CYP46A1, an enzyme that controls cholesterol turnover in the brain.
The Journal of biological chemistry 20101008
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[Tranylcypromine for chronic therapy-resistant agoraphobia with panic disorder and recurrent depressive disorder].
Psychiatrische Praxis 20101001
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Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1 .
Biochemistry 20100803
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limited potentiation of blood pressure in response to oral tyramine by the anti-Parkinson brain selective multifunctional monoamine oxidase-AB inhibitor, M30.
Neurotoxicity research 20100801
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Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2.
Journal of the American Chemical Society 20100519
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Comparative analysis of small molecules and histone substrate analogues as LSD1 lysine demethylase inhibitors.
Journal of the American Chemical Society 20100310
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Psychopharmacology 20100301
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Double-blind comparison of 30 and 60 mg tranylcypromine daily in patients with panic disorder comorbid with social anxiety disorder.
Psychiatry research 20100227
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Chemical research in toxicology 20100101
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Degeneration of dopaminergic neurons induced by thrombin injection in the substantia nigra of the rat is enhanced by dexamethasone: role of monoamine oxidase enzyme.
Neurotoxicology 20100101
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Gas chromatography-mass spectrometry detection of a norfluoxetine artifact in hydrolyzed urine samples may falsely indicate tranylcypromine ingestion.
Journal of analytical toxicology 20100101
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Delirium, thrombocytopenia, insomnia, and mild liver damage associated with MAOI withdrawal.
European journal of clinical pharmacology 20091201
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TCP-FA4: a derivative of tranylcypromine showing improved blood-brain permeability.
Biochemical pharmacology 20091201
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Generation of human-induced pluripotent stem cells in the absence of exogenous Sox2.
Stem cells (Dayton, Ohio) 20091201
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Ovariectomy increases the formation of prostanoids and modulates their role in acetylcholine-induced relaxation and nitric oxide release in the rat aorta.
Cardiovascular research 20091101
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Ti: myths about monoamine oxidase inhibitors perpetuated.
The Australian and New Zealand journal of psychiatry 20091101
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Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands.
The Biochemical journal 20091023
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Brain research bulletin 20090828
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Journal of psychopharmacology (Oxford, England) 20090801
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Functional expression, inhibition and induction of CYP enzymes in HepaRG cells.
Toxicology in vitro : an international journal published in association with BIBRA 20090601
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Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20090416
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Antidepressants reveal differential effect against 1-methyl-4-phenylpyridinium toxicity in differentiated PC12 cells.
European journal of pharmacology 20090214
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Inhibition of monoamine oxidases desensitizes 5-HT1A autoreceptors and allows nicotine to induce a neurochemical and behavioral sensitization.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20090128
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Molecular control of HIV-1 postintegration latency: implications for the development of new therapeutic strategies.
Retrovirology 20090101
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Neurochemical, behavioral, and physiological effects of pharmacologically enhanced serotonin levels in serotonin transporter (SERT)-deficient mice.
Psychopharmacology 20081201
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Antidepressant activity of curcumin: involvement of serotonin and dopamine system.
Psychopharmacology 20081201
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Differential effects of the antidepressants tranylcypromine and fluoxetine on limbic cannabinoid receptor binding and endocannabinoid contents.
Journal of neural transmission (Vienna, Austria : 1996) 20081201
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Electroconvulsive therapy and monoamine oxidase inhibitors.
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20081201
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Characterization of CYP2A13*2, a variant cytochrome P450 allele previously found to be associated with decreased incidences of lung adenocarcinoma in smokers.
Drug metabolism and disposition: the biological fate of chemicals 20081101
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Safety of high-intensity treatment with the irreversible monoamine oxidase inhibitor tranylcypromine in patients with treatment-resistant depression.
Pharmacopsychiatry 20081101
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Antidepressant treatments regulate matrix metalloproteinases-2 and -9 (MMP-2/MMP-9) and tissue inhibitors of the metalloproteinases (TIMPS 1-4) in the adult rat hippocampus.
Synapse (New York, N.Y.) 20080801
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Complexes of the copper-containing amine oxidase from Arthrobacter globiformis with the inhibitors benzylhydrazine and tranylcypromine.
Acta crystallographica. Section F, Structural biology and crystallization communications 20080701
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Chronic ouabain treatment increases the contribution of nitric oxide to endothelium-dependent relaxation.
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Facile synthesis of substituted trans-2-arylcyclopropylamine inhibitors of the human histone demethylase LSD1 and monoamine oxidases A and B.
Bioorganic & medicinal chemistry letters 20080515
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Juvenile rats in the forced-swim test model the human response to antidepressant treatment for pediatric depression.
Psychopharmacology 20080401
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Neurochemical research 20080301
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PloS one 20080101
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Neuropharmacology 20071001
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Arzneimittel-Forschung 20050101
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Current medicinal chemistry 20040801
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Canadian journal of psychiatry. Revue canadienne de psychiatrie 20040801
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Nederlands tijdschrift voor geneeskunde 20031004
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Neurology 20030923
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European psychiatry : the journal of the Association of European Psychiatrists 20030801
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Induction of hepatic heme oxygenase-1 by diclofenac in rodents: role of oxidative stress and cytochrome P-450 activity.
Journal of hepatology 20030601
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In vitro inhibition of human small intestinal and liver microsomal astemizole O-demethylation: different contribution of CYP2J2 in the small intestine and liver.
Xenobiotica; the fate of foreign compounds in biological systems 20030601
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Inhibition of six copper-containing amine oxidases by the antidepressant drug tranylcypromine.
Biochimica et biophysica acta 20030411
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Pharmacology, biochemistry, and behavior 20030401
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[11C]-DASB, a tool for in vivo measurement of SSRI-induced occupancy of the serotonin transporter: PET characterization and evaluation in cats.
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Rapid communications in mass spectrometry : RCM 20030101
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Psychosomatic medicine 20030101
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Neuroscience 20030101
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Psychopharmacology bulletin 20030101
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Neuropharmacology 20021101
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Probing the catalytic mechanism of Escherichia coli amine oxidase using mutational variants and a reversible inhibitor as a substrate analogue.
The Biochemical journal 20020801
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Successful treatment of a complicated case of neuroleptic malignant syndrome.
Intensive care medicine 20020701
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The Journal of biological chemistry 20020419
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Journal of neural transmission (Vienna, Austria : 1996) 20020301
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Anesteziologiia i reanimatologiia 20020101
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Repeated treatment with imipramine, fluvoxamine and tranylcypromine decreases the number of escape failures by activating dopaminergic systems in a rat learned helplessness test.
Life sciences 20010907
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Drug metabolism and disposition: the biological fate of chemicals 20010601
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European journal of medicinal chemistry 20010601
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Mechanisms of relaxation induced by angiotensin II in isolated canine and human uterine arteries.
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Nederlands tijdschrift voor geneeskunde 19930501
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Tranylcypromine withdrawal phenomena.
Journal of psychiatry & neuroscience : JPN 19930101
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Abuse of monoamine oxidase inhibitors.
The American journal of drug and alcohol abuse 19920101
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Capgras syndrome in association with lithium toxicity.
The British journal of psychiatry : the journal of mental science 19911201
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Disseminated intravascular coagulation and acute myoglobinuric renal failure: a consequence of the serotonergic syndrome.
Journal of clinical psychopharmacology 19910801
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Interaction of butorphanol, with monoamine oxidase inhibitor, tranylcypromine.
Forensic science international 19910301
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Symptoms of major depression: acute effect of withdrawing antidepressants.
Acta psychiatrica Scandinavica 19910301
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Treatment of panic disorder and benzodiazepine withdrawal with valproate.
The Journal of neuropsychiatry and clinical neurosciences 19910101
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[The comparative influence of pyrazidol, inkazan and other antidepressant monoamine oxidase inhibitors on the pressor effect of tyramine].
Farmakologiia i toksikologiia 19910101
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Monosodium glutamate and tranylcypromine administration in healthy subjects.
The Journal of clinical psychiatry 19900701
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Adverse consequences of fluoxetine-MAOI combination therapy.
The Journal of clinical psychiatry 19900601
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Afternoon fatigue and somnolence associated with tranylcypromine treatment.
The Journal of clinical psychiatry 19900501
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Hypertensive crisis precipitated by a monoamine oxidase inhibitor in a patient with phaeochromocytoma.
BMJ (Clinical research ed.) 19900303
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Hypertensive episodes with tranylcypromine treatment.
Journal of clinical psychopharmacology 19890601
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Hypertensive crisis and broad complex bradycardia after a single dose of monoamine oxidase inhibitor.
BMJ (Clinical research ed.) 19890408
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Autoinduction of hypertensive reactions by tranylcypromine?
Journal of clinical psychopharmacology 19890201
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Common side effects associated with monoamine oxidase inhibitors.
Progress in neuro-psychopharmacology & biological psychiatry 19890101
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Severe daytime somnolence in patients treated with an MAOI.
The American journal of psychiatry 19881201
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Buspirone-induced hypomania: a case report.
Journal of clinical psychopharmacology 19880601
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Cardiac myonecrosis and monoamine oxidase inhibitor therapy.
The American journal of medicine 19871001
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Pharmacological characteristics of tremor, rigidity and hypokinesia induced by reserpine in rat.
Neuropharmacology 19870901
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Fatal disseminated intravascular coagulation following a monoamine oxidase inhibitor/tricyclic interaction.
Anaesthesia 19870701
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Treatment of MAOI hypertensive crisis with sublingual nifedipine.
The Journal of clinical psychiatry 19870601
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Hypertension during anaesthesia with monoamine oxidase inhibitors.
Anaesthesia 19870601
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Cardiac myonecrosis in hypertensive crisis associated with monoamine oxidase inhibitor therapy.
The American journal of medicine 19870501
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Yohimbine- and tranylcypromine-induced postural hypotension.
The American journal of psychiatry 19870101
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Two cases of hypomania following the addition of L-tryptophan to a monoamine oxidase inhibitor.
The American journal of psychiatry 19851201
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Successful treatment of a monoamine oxidase inhibitor-tyramine hypertensive emergency with intravenous labetalol.
The New England journal of medicine 19850704
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Toxic reactions to the combination of monoamine oxidase inhibitors and tryptophan.
The American journal of psychiatry 19850401
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Adverse reactions to monoamine oxidase inhibitors. Part II. Treatment correlates and clinical management.
Journal of clinical psychopharmacology 19850201
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Brain monoamine oxidase in suckling rabbits treated with organophosphorus compound. I. Acute intoxication.
Acta physiologica Polonica 19840101
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The safety and efficacy of combined amitriptyline and tranylcypromine antidepressant treatment. A controlled trial.
Archives of general psychiatry 19830601
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Does prostacyclin mediate alpha-adrenergic induced hypotension?
Documenta ophthalmologica. Advances in ophthalmology 19820930
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Reversal by bethanechol of sexual dysfunction caused by anticholinergic antidepressants.
The American journal of psychiatry 19820901
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Hypertensive crisis resulting from avocados and a MAO inhibitor.
Drug intelligence & clinical pharmacy 19811101
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Atrial flutter/fibrillation associated with tranylcypromine treatment.
Journal of clinical psychopharmacology 19811101
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Effect of caroxazone, a new antidepressant drug, on monoamine oxidases in healthy volunteers.
British journal of clinical pharmacology 19810501
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Alteration of lidocaine- or procaine-induced convulsions by manipulation of brain amines.
Journal of dental research 19810201
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Reduction of ECS-induced retrograde amnesia of passive avoidance conditioning after 5,7-dihydroxytryptamine median raphe nucleus lesion in the rat.
Neuropsychobiology 19810101
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Linoleic acid in the treatment of lithium toxicity and familial tremor.
Prostaglandins and medicine 19800401
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Hoarseness and aphonia as a side effect of tricyclic antidepressants.
The American journal of psychiatry 19791201
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Tranylcypromine induced hypertension is not mediated by the inhibition of prostacyclin synthesis.
Prostaglandins and medicine 19791001
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Degraded protein-containing food and monoamine oxidase inhibitors.
The American journal of psychiatry 19771201
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Repeated chlorpromazine administration increases a behavioural response of rats to 5-hydroxytryptamine receptor stimulation.
British journal of pharmacology 19770201
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Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides.
Prostaglandins 19761101
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The tranylcypromine isomers: a controlled clinical trial.
The American journal of psychiatry 19740901
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Letter: Side effect of tranylcypromine.
British medical journal 19740831
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Tricyclic antidepressants and monoamine oxidase inhibitors.
Archives of general psychiatry 19710601
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Severe hyperpyrexia due to tranylcypromine-amphetamine toxicity.
Annals of internal medicine 19690301
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Effect of certain monoamine oxidase inhibitors on isoproterenol-induced cardiac necrosis in rats.
Proceedings of the Western Pharmacology Society 19660101