5418-93-9 | 6-Chloro-1h-benzo[d]imidazol-2-amine

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$32.00	$23.00
250mg	95%	in stock	$46.00	$33.00
1g	95%	in stock	$138.00	$97.00
5g	95%	in stock	$586.00	$411.00

Description

• Catalog Number: AG19183
• Chemical Name: 6-Chloro-1h-benzo[d]imidazol-2-amine
• CAS Number: 5418-93-9
• Molecular Formula: C7H6ClN3
• Molecular Weight: 167.5956
• MDL Number: MFCD00749332
• SMILES: Clc1ccc2c(c1)nc([nH]2)N
• NSC Number: 10545

Computed Properties

• Complexity: 153
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• XLogP3: 1.9

Literature

• Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors.

  The Biochemical journal 20101001

• Fragment-based discovery and optimization of BACE1 inhibitors.

  Bioorganic & medicinal chemistry letters 20100901

• One scaffold, three binding modes: novel and selective pteridine reductase 1 inhibitors derived from fragment hits discovered by virtual screening.

  Journal of medicinal chemistry 20090723

• Molecular modeling of some 1H-benzimidazole derivatives with biological activity against Entamoeba histolytica: a comparative molecular field analysis study.

  Bioorganic & medicinal chemistry 20070115

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Conformationally-restricted analogues and partition coefficients of the 5-HT3 serotonin receptor ligands meta-chlorophenylbiguanide (mCPBG) and meta-chlorophenylguanidine (mCPG).

  Bioorganic & medicinal chemistry letters 20030324

• Synthesis and antiparasitic activity of 1H-benzimidazole derivatives.

  Bioorganic & medicinal chemistry letters 20020819