5470-11-1 | Hydroxylamine hydrochloride

Packsize	Purity	Availability	Price	Discounted Price
5g	97%	in stock	$12.00	$8.00
25g	97%	in stock	$15.00	$10.00
100g	97%	in stock	$19.00	$13.00
500g	97%	in stock	$46.00	$32.00

Description

• Catalog Number: AB51649
• Chemical Name: Hydroxylamine hydrochloride
• CAS Number: 5470-11-1
• Molecular Formula: ClH4NO
• Molecular Weight: 69.4909
• MDL Number: MFCD00051089
• SMILES: NO.Cl
• NSC Number: 26250

Computed Properties

• Complexity: 2
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 3
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 3

Literature

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  Toxicology letters 20170315

• 4-Hydroxy TEMPO attenuates dichlorvos induced microglial activation and apoptosis.

  ACS chemical neuroscience 20140219

• The nitroxide TEMPO is an efficient scavenger of protein radicals: cellular and kinetic studies.

  Free radical biology & medicine 20121101

• Sequential α-ketoacid-hydroxylamine (KAHA) ligations: synthesis of C-terminal variants of the modifier protein UFM1.

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• Functional analysis of the conserved histidine residue of Bamboo mosaic virus capping enzyme in the activity for the formation of the covalent enzyme-m7GMP intermediate.

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• A turn-on fluorescent probe based on hydroxylamine oxidation for detecting ferric ion selectively in living cells.

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• Chemical protein synthesis by chemoselective α-ketoacid-hydroxylamine (KAHA) ligations with 5-oxaproline.

  Angewandte Chemie (International ed. in English) 20120521

• Sensitive detection of hydroxylamine at a simple baicalin carbon nanotubes modified electrode.

  Talanta 20120515

• Assessing the reactivation efficacy of hydroxylamine anion towards VX-inhibited AChE: a computational study.

  Journal of molecular modeling 20120501

• Effects of short and prolonged mild intracellular nitric oxide manipulations on various aspects of insulin secretion in INS-1E β-cells.

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• Model studies on iTRAQ modification of peptides: sequence-dependent reaction specificity.

  Journal of proteome research 20120302

• Photo-induced bleaching of sensory rhodopsin II (phoborhodopsin) from Halobacterium salinarum by hydroxylamine: identification of the responsible intermediates.

  Journal of photochemistry and photobiology. B, Biology 20120105

• Development of an LC-MS/MS method to quantify sex hormones in bovine milk and influence of pregnancy in their levels.

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• Application of Ni(II)-assisted peptide bond hydrolysis to non-enzymatic affinity tag removal.

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• Oxidative damage to DNA constituents by iron-mediated Fenton reactions: the deoxyadenosine family.

  Journal of biomolecular structure & dynamics 20120101

• Evaluation of the Forrester-Hepburn mechanism as an artifact source in ESR spin-trapping.

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• Effects of hydrogen sulfide synthesis inhibitors on posthypoxic ventilatory behavior in the C57BL/6J mouse.

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• Kinetics and mechanism of the oxidation of hydroxylamine by a {Mn3O4}4+ core in aqueous acidic media.

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• ANAMMOX process start up and stabilization with an anaerobic seed in Anaerobic Membrane Bioreactor (AnMBR).

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• N-nitrosamines formation from secondary amines by nitrogen fixation on the surface of activated carbon.

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• Conformational switching immobilized hairpin DNA probes following subsequent expanding of gold nanoparticles enables visual detecting sequence-specific DNA.

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• Effects of inhibitors of hydrogen sulphide synthesis on rat colonic motility.

  British journal of pharmacology 20110901

• The oxidative and nitrosative stress defence network of Wolinella succinogenes: cytochrome c nitrite reductase mediates the stress response to nitrite, nitric oxide, hydroxylamine and hydrogen peroxide.

  Environmental microbiology 20110901

• Intein lacking conserved C-terminal motif G retains controllable N-cleavage activity.

  The FEBS journal 20110901

• Thermal decay of TEMPO in acidic media via an N-oxoammonium salt intermediate.

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• Probing the reactivation process of sarin-inhibited acetylcholinesterase with α-nucleophiles: hydroxylamine anion is predicted to be a better antidote with DFT calculations.

  Journal of molecular graphics & modelling 20110801

• Ultrasensitive and selective DNA detection by hydroxylamine assisted gold nanoparticle amplification.

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• Structural characteristics around the β-ionone ring of the retinal chromophore in Salinibacter sensory rhodopsin I.

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• Synthesis and anti-microbial activity of hydroxylammonium ionic liquids.

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• An improved bioprocess for synthesis of acetohydroxamic acid using DTT (dithiothreitol) treated resting cells of Bacillus sp. APB-6.

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• Cross-linking by protein oxidation in the rapidly setting gel-based glues of slugs.

  The Journal of experimental biology 20110515

• Strong enhancement on fenton oxidation by addition of hydroxylamine to accelerate the ferric and ferrous iron cycles.

  Environmental science & technology 20110501

• EPR detection of cellular and mitochondrial superoxide using cyclic hydroxylamines.

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• The cardiovascular inhibition functions of hydrogen sulfide within the nucleus tractus solitarii are mediated by the activation of KATP channels and glutamate receptors mechanisms.

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• Synthesis, characterization and electrocatalytic activity of fused gold nanoparticles.

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• Matrix solid phase dispersion-assisted BCR sequential extraction method for metal partitioning in surface estuarine sediments.

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• Site-specific labeling of proteins for single-molecule FRET measurements using genetically encoded ketone functionalities.

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• [Glycosides of hydroxylamine derivatives. I. phase transfer synthesis and study of isatine-3-oximes glucosaminides influence on bacterial luminescence].

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• Glucose stimulation of protein acylation in the pancreatic β-cell.

  Life sciences 20101218

• Accumulation of true single strand breaks and AP sites in base excision repair deficient cells.

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• Different reactivity of hydroxylamine with carbamoyl azides and carbamoyl cyanides: synthesis of hydroxyureas and carbamoyl amidoximes.

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• Re-evaluation of superoxide scavenging capacity of xanthohumol.

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• Hydroxylamine as a thermal destabiliser of bacteriorhodopsin.

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• Development and validation of fixed-time method for the determination of isoxsuprine hydrochloride in commercial dosages forms.

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• Colorimetric determination of simvastatin and lovastatin in pure form and in pharmaceutical formulations.

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• FTIR study of the photoreaction of bovine rhodopsin in the presence of hydroxylamine.

  The journal of physical chemistry. B 20100715

• Comparative reactivity of mismatched and unpaired bases in relation to their type and surroundings. Chemical cleavage of DNA mismatches in mutation detection analysis.

  Biochimie 20100701

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• Transition states of uncatalyzed hydrolysis and aminolysis reactions of a ribosomal P-site substrate determined by kinetic isotope effects.

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• Vasoactivity of hydrogen sulfide in normoxic and anoxic turtles (Trachemys scripta).

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• Transglutaminase catalysis of modified whey protein dispersions.

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• Electron transfer between exogenous electron donors and reaction center of photosystem 2.

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• Detection limits of electron and electron capture negative ionization-mass spectrometry for aldehydes derivatized with o-(2,3,4,5,6-pentafluorobenzyl)-hydroxylamine hydrochloride.

  Journal of the American Society for Mass Spectrometry 20100401

• Highly sensitive determination of hydroxylamine using fused gold nanoparticles immobilized on sol-gel film modified gold electrode.

  Analytica chimica acta 20100324

• Hydrogen peroxide mediates the expression of ascorbate-related genes in response to methanol stimulation in Oncidium.

  Journal of plant physiology 20100315

• Synthesis of porous acrylonitrile/methyl acrylate copolymer beads by suspended emulsion polymerization and their adsorption properties after amidoximation.

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• PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA.

  The Journal of biological chemistry 20100312

• Polycyclic N-heterocyclic compounds. Part 62: Reaction of N-(quinazolin-4-yl)amidine derivatives with hydroxylamine hydrochloride and anti-platelet aggregation activity of the products.

  Chemical & pharmaceutical bulletin 20100301

• Molecular mechanisms of rhodopsin retinitis pigmentosa and the efficacy of pharmacological rescue.

  Journal of molecular biology 20100205

• Novel convenient synthesis of biologically active esters of hydroxylamine.

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• The first examples of chemical modification of oligomycin A.

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• Metabolic and chemical origins of cross-reactive immunological reactions to arylamine benzenesulfonamides: T-cell responses to hydroxylamine and nitroso derivatives.

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• Synthesis and characterization of fatty hydroxamic acids from triacylglycerides.

  Journal of oleo science 20100101

• Determination of the hormonal growth promoter 17alpha-methyltestosterone in food-producing animals: bovine hair analysis by HPLC-MS/MS.

  Meat science 20100101

• Identification of rat cytochromes P450 metabolizing N-(2-methoxyphenyl)hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole.

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• [Immunobiologic characteristics of carbohydrate-containing preparations of Haemophilus influenzae].

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• Nitroxyl radical plus hydroxylamine pseudo self-exchange reactions: tunneling in hydrogen atom transfer.

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• Influence of hydroxylamine conformation on stereocontrol in Pd-catalyzed isoxazolidine-forming reactions.

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• Rearrangement of beta-chloro N-oxides to hydroxylamines: opening of the oxazetidinium intermediate by different nucleophiles.

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• Chapter 17. Siderophore biosynthesis a substrate specificity assay for nonribosomal peptide synthetase-independent siderophore synthetases involving trapping of acyl-adenylate intermediates with hydroxylamine.

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• Modulation of glucose induced oscillatory [Ca2+]i signals by nitric oxide in ob/ob mouse pancreatic beta-cells.

  Mymensingh medical journal : MMJ 20090101

• Lateral diffusion of rhodopsin in photoreceptor membrane: a reappraisal.

  Molecular vision 20090101

• Reaction of cytosine with bisulfite and hydroxylamine.

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• The chemical cleavage of mismatch for the detection of mutations in long DNA fragments.

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• Spectrofotometric determination of copper in sugar cane spirit using biquinoline in the presence of ethanol and Triton X-100.

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• Fibroblast growth factor-regulated palmitoylation of the neural cell adhesion molecule determines neuronal morphogenesis.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080903

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• Kinetic and product distribution analysis of NO* reductase activity in Nitrosomonas europaea hydroxylamine oxidoreductase.

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• Catalytic C-H amination for the preparation of substituted 1,2-diamines.

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• Transition metal coordination chemistry ofN,N-bis(2-{pyrid-2-ylethyl})hydroxylamine.

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• The effect of guanylate cyclase inhibitors on non-adrenergic and non-cholinergic neurogenic relaxations of the South American opossum lower esophageal sphincter.

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• Peripheral myelin of Xenopus laevis: role of electrostatic and hydrophobic interactions in membrane compaction.

  Journal of structural biology 20080401

• A mitochondria-targeted nitroxide is reduced to its hydroxylamine by ubiquinol in mitochondria.

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  Molecular microbiology 20080401

• Visualization of transient ultra-weak protein self-association in solution using paramagnetic relaxation enhancement.

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  Molecular and cellular biochemistry 20080301

• OYE flavoprotein reductases initiate the condensation of TNT-derived intermediates to secondary diarylamines and nitrite.

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• The synthesis of unsubstituted cyclic imides using hydroxylamine under microwave irradiation.

  Molecules (Basel, Switzerland) 20080125

• OT-674 suppresses photooxidative processes initiated by an RPE lipofuscin fluorophore.

  Photochemistry and photobiology 20080101

• Synthesis and physiological activity of thiophenes and furans with 3- and 4-methoxyacetophenone derivatives.

  Journal of oleo science 20080101

• Quantitation of the effect of hydroxylamine on rhodopsin palmitylation.

  Photochemistry and photobiology 20080101

• Expression and hydroxylamine cleavage of thymosin alpha 1 concatemer.

  Journal of biomedicine & biotechnology 20080101

• Luminescence experiments involved in the mechanism of streptozotocin diabetes and cataract formation.

  Luminescence : the journal of biological and chemical luminescence 20080101

• Detection, isolation and characterization of a root-exuded compound, methyl 3-(4-hydroxyphenyl) propionate, responsible for biological nitrification inhibition by sorghum (Sorghum bicolor).

  The New phytologist 20080101

• The reaction of cytosine with bisulfite by base flipping from the duplex.

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• Characterization and partial isolation of ouabain-insensitive Na(+) -ATPase in MDCK I cells.

  Biochimie 20071101

• An octaheme c-type cytochrome from Shewanella oneidensis can reduce nitrite and hydroxylamine.

  FEBS letters 20070807

• Discovery and characterization of a cytochrome b5 variant in humans with impaired hydroxylamine reduction capacity.

  Pharmacogenetics and genomics 20070801

• Mechanisms and kinetics of chelating reaction between novel chitosan derivatives and Zn(II).

  Journal of hazardous materials 20070719

• S-acylation regulates Kv1.5 channel surface expression.

  American journal of physiology. Cell physiology 20070701

• In vivo detection of intrinsic reactive oxygen species using acyl-protected hydroxylamine in puromycin nephrosis.

  Free radical research 20070701

• Selective cleavage of isoaspartyl peptide bonds by hydroxylamine after methyltransferase priming.

  Analytical biochemistry 20070501

• Kinetic and structural characterisation of Escherichia coli nitroreductase mutants showing improved efficacy for the prodrug substrate CB1954.

  Journal of molecular biology 20070427

• Structures of cyanide, nitric oxide and hydroxylamine complexes of Arthromyces ramosusperoxidase at 100 K refined to 1.3 A resolution: coordination geometries of the ligands to the haem iron.

  Acta crystallographica. Section D, Biological crystallography 20070401

• Protective effect of TEMPOL derivatives against light-induced retinal damage in rats.

  Investigative ophthalmology & visual science 20070401

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• A screening system for active and enantioselective amidase based on its acyl transfer activity.

  Applied microbiology and biotechnology 20070201

• Reversion of structure-activity relationships of antitumor platinum complexes by acetoxime but not hydroxylamine ligands.

  Molecular pharmacology 20070101

• Hypotensive effect of hydroxylamine, an endogenous nitric oxide donor and SSAO inhibitor.

  Journal of neural transmission (Vienna, Austria : 1996) 20070101

• Primary tert- and sec-allylamines via palladium-catalyzed hydroamination and allylic substitution with hydrazine and hydroxylamine derivatives.

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  Molekuliarnaia biologiia 20070101

• Efficient intramolecular general acid catalysis of nucleophilic attack on a phosphodiester.

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• Bradykinin augments insulin-stimulated glucose transport in rat adipocytes via endothelial nitric oxide synthase-mediated inhibition of Jun NH2-terminal kinase.

  Diabetes 20061001

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  Biochemical and biophysical research communications 20060901

• Synthesis of mono- and symmetrical di-N-hydroxy- and N-aminoguanidines.

  The Journal of organic chemistry 20060901

• Kinetic properties of wild-type and altered recombinant amidases by the use of ion-selective electrode assay method.

  Analytical biochemistry 20060815

• Synthesis of alpha-amino acid precursors directly from aldehydes using masked acyl cyanide reagents and N,O-dialkylated hydroxylamines.

  The Journal of organic chemistry 20060804

• Differential recognition of citrate and a metal-citrate complex by the bacterial chemoreceptor Tcp.

  The Journal of biological chemistry 20060630

• Microbial indicators of heavy metal contamination in urban and rural soils.

  Chemosphere 20060601

• Electrochemical Time-of-Flight in crosslinked collagen matrix solution: implications of structural changes for drug delivery systems.

  Journal of controlled release : official journal of the Controlled Release Society 20060515

• Extraction of arsenate and arsenite species from soils and sediments.

  Environmental pollution (Barking, Essex : 1987) 20060501

• Enzyme-free amperometric sensing of glucose by using gold nanoparticles.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20060320

• Discriminating formation of HNO from other reactive nitrogen oxide species.

  Free radical biology & medicine 20060315

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  Biochemistry 20060214

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  Archives of biochemistry and biophysics 20060201

• Statistical evaluation of the bioavailability of heavy metals from contaminated soils to vegetables.

  Bulletin of environmental contamination and toxicology 20060201

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• Ovalbumin-related gene Y protein bears carbohydrate chains of the ovomucoid type.

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  Journal of the American Chemical Society 20051116

• Regulation of nitrate reductase activity in Mycobacterium tuberculosis by oxygen and nitric oxide.

  Microbiology (Reading, England) 20051101

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  The Journal of biological chemistry 20051021

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  Biophysical journal 20051001

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  The Journal of biological chemistry 20050930

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  Science (New York, N.Y.) 20050923

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  Analytical and bioanalytical chemistry 20050901

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  The Journal of biological chemistry 20050826

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  Chemosphere 20050801

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  The Journal of experimental biology 20050801

• Simultaneous analysis of several antiretroviral nucleosides in rat-plasma by high-performance liquid chromatography with UV using acetic acid/hydroxylamine buffer Test of this new volatile medium-pH for HPLC-ESI-MS/MS.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050725

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  Biochemistry 20050719

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  Biochemical pharmacology 20050715

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  The Journal of biological chemistry 20050617

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  European journal of pharmacology 20050615

• Kinetics and products of the OH radical-initiated reaction of 3-methyl-2-butenal.

  Physical chemistry chemical physics : PCCP 20050607

• Inactivation of bacterial DD-peptidase by beta-sultams.

  Biochemistry 20050531

• Light-dependent redistribution of arrestin in vertebrate rods is an energy-independent process governed by protein-protein interactions.

  Neuron 20050519

• The effect of hydroxylamine on KATP channels in vascular smooth muscle and underlying mechanisms.

  Molecular pharmacology 20050501

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  Archives of biochemistry and biophysics 20050415

• Structural and kinetic analyses of arginine residues in the active site of the acetate kinase from Methanosarcina thermophila.

  The Journal of biological chemistry 20050318

• Effect of the covalently linked fatty acid 18-MEA on the nanotribology of hair's outermost surface.

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  Free radical biology & medicine 20050101

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