-
Inhibition of matrix metalloproteinase-2 by halofuginone is mediated by the Egr1 transcription factor.
Anti-cancer drugs 20121101
-
Halofuginone prevents estrogen-deficient osteoporosis in mice.
Journal of cellular biochemistry 20121001
-
Validation of the aging hen (Gallus gallus domesticus) as an animal model for uterine leiomyomas.
Biology of reproduction 20121001
-
Halofugine prevents cutaneous graft versus host disease by suppression of Th17 differentiation.
Hematology (Amsterdam, Netherlands) 20120901
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Anticoccidial effect of halofuginone hydrobromide against Eimeria tenella with associated histology.
Parasitology research 20120801
-
Halofuginone inhibits multiple myeloma growth in vitro and in vivo and enhances cytotoxicity of conventional and novel agents.
British journal of haematology 20120601
-
TH17 cells are critical for skin-specific pathological injury in acute graft-versus-host disease.
Transplantation proceedings 20120601
-
Local inhibition of angiogenesis by halofuginone coated silicone materials.
Journal of materials science. Materials in medicine 20120501
-
Characterization of Plasmodium liver stage inhibition by halofuginone.
ChemMedChem 20120501
-
Reduction of burn scar formation by halofuginone-eluting silicone gel sheets: a controlled study on nude mice.
Annals of plastic surgery 20120301
-
Surgical stress resistance induced by single amino acid deprivation requires Gcn2 in mice.
Science translational medicine 20120125
-
Th17 response and inflammatory autoimmune diseases.
International journal of inflammation 20120101
-
Halofuginone down-regulates Smad3 expression and inhibits the TGFbeta-induced expression of fibrotic markers in human corneal fibroblasts.
Molecular vision 20120101
-
Altered tryptophan metabolism as a paradigm for good and bad aspects of immune privilege in chronic inflammatory diseases.
Frontiers in immunology 20120101
-
The immune diet: meeting the metabolic demands of lymphocyte activation.
F1000 biology reports 20120101
-
Involvement of host stroma cells and tissue fibrosis in pancreatic tumor development in transgenic mice.
PloS one 20120101
-
Determination of eleven coccidiostats in animal feed by liquid chromatography-tandem mass spectrometry at cross contamination levels.
Analytica chimica acta 20110826
-
Development and validation of a multi-residue liquid chromatography-tandem mass spectrometry confirmatory method for eleven coccidiostats in eggs.
Analytica chimica acta 20110826
-
[An absence of donor TH17 differentiation ameliorates dermal tissue damage].
Zhonghua yi xue za zhi 20110712
-
Efficacy of halofuginone lactate in the prevention of cryptosporidiosis in dairy calves.
The Veterinary record 20110514
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[The role of Th17 cells in early onset of mice acute graft versus host disease].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110501
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Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum.
PLoS genetics 20110401
-
Light-chain shuffling from an antigen-biased phage pool allows 185-fold improvement of an anti-halofuginone single-chain variable fragment.
Analytical biochemistry 20110301
-
Is there any synergic effect for coadministration of mitomycin C and halofuginone on the skin wound healing?
American journal of otolaryngology 20110101
-
Phase II AIDS Malignancy Consortium trial of topical halofuginone in AIDS-related Kaposi sarcoma.
Journal of acquired immune deficiency syndromes (1999) 20110101
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Halofuginone and muscular dystrophy.
Histology and histopathology 20110101
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Halofuginone-coated urethral catheters prevent periurethral spongiofibrosis in a rat model of urethral injury.
Journal of endourology 20110101
-
Identification of Baicalin as an immunoregulatory compound by controlling T(H)17 cell differentiation.
PloS one 20110101
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How can natural products serve as a viable source of lead compounds for the development of new/novel anti-malarials?
Malaria journal 20110101
-
Natural products as starting points for future anti-malarial therapies: going back to our roots?
Malaria journal 20110101
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The Ras antagonist, farnesylthiosalicylic acid (FTS), decreases fibrosis and improves muscle strength in dy/dy mouse model of muscular dystrophy.
PloS one 20110101
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Illthrift in suckling lambs secondary to umbilical infections and possible implication of cryptosporidiosis as a risk factor.
Veterinary medicine international 20110101
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Aberrant repair and fibrosis development in skeletal muscle.
Skeletal muscle 20110101
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Th17 cells and IL-17 in protective immunity to vaginal candidiasis.
PloS one 20110101
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Calf health from birth to weaning. II. Management of diarrhoea in pre-weaned calves.
Irish veterinary journal 20110101
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Probiotics for the control of parasites: an overview.
Journal of parasitology research 20110101
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Microarray profiling reveals the integrated stress response is activated by halofuginone in mammary epithelial cells.
BMC research notes 20110101
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Halofuginone has anti-proliferative effects in acute promyelocytic leukemia by modulating the transforming growth factor beta signaling pathway.
PloS one 20110101
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Efficacy of topical halofuginone in myringotomy patency.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20101101
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Pharmacokinetic and tissue distribution of doxycycline in broiler chickens pretreated with either: diclazuril or halofuginone.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20101101
-
Inhibition of pancreatic stellate cell activation by halofuginone prevents pancreatic xenograft tumor development.
Pancreas 20101001
-
The effects of methylprednisolone and halofuginone on preventing esophageal and hypopharyngeal fibrosis in delivered radiotherapy.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20100901
-
Is feline acquired reactive perforating collagenosis a wound healing defect? Treatment with topical betamethasone and halofuginone appears beneficial.
Veterinary dermatology 20100801
-
Fibrosis inhibition and muscle histopathology improvement in laminin-alpha2-deficient mice.
Muscle & nerve 20100801
-
Surface modification of silicone breast implants by binding the antifibrotic drug halofuginone reduces capsular fibrosis.
Plastic and reconstructive surgery 20100701
-
Innovative therapies for systemic sclerosis.
Current opinion in rheumatology 20100501
-
Halofuginone inhibits Smad3 phosphorylation via the PI3K/Akt and MAPK/ERK pathways in muscle cells: effect on myotube fusion.
Experimental cell research 20100401
-
Radioprotectors and mitigators of radiation-induced normal tissue injury.
The oncologist 20100401
-
The antifibrotic drug halofuginone inhibits proliferation and collagen production by human leiomyoma and myometrial smooth muscle cells.
Fertility and sterility 20100301
-
Halofuginone, a specific inhibitor of collagen type 1 synthesis, ameliorates oxidant colonic damage in rats with experimental colitis.
Digestive diseases and sciences 20100301
-
Halofuginone enhances the radiation sensitivity of human tumor cell lines.
Cancer letters 20100301
-
Dihydroxylation of vinyl sulfones: stereoselective synthesis of (+)- and (-)-febrifugine and halofuginone.
The Journal of organic chemistry 20100115
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Halofuginone- and chitosan-coated amnion membranes demonstrate improved abdominal adhesion prevention.
TheScientificWorldJournal 20100101
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Oesophageal foreign bodies in dogs: factors affecting success of endoscopic retrieval.
Irish veterinary journal 20100101
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Validation of a multi-residue liquid chromatography-tandem mass spectrometry confirmatory method for 10 anticoccidials in eggs according to Commission Decision 2002/657/EC.
Journal of chromatography. A 20091113
-
Multi-residue confirmatory method for the determination of twelve coccidiostats in chicken liver using liquid chromatography tandem mass spectrometry.
Journal of chromatography. A 20091113
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Systematic review and meta-analyses of the effects of halofuginone against calf cryptosporidiosis.
Preventive veterinary medicine 20091001
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Halofuginone mediated protection against radiation-induced leg contracture.
International journal of oncology 20090801
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Combination of cell culture and quantitative PCR for screening of drugs against Cryptosporidium parvum.
Veterinary parasitology 20090610
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Immunology. Amino acid addiction.
Science (New York, N.Y.) 20090605
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Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response.
Science (New York, N.Y.) 20090605
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Recent advances in the treatment of systemic sclerosis.
Clinical reviews in allergy & immunology 20090601
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Inhibition of transforming growth factor beta signaling by halofuginone as a modality for pancreas fibrosis prevention.
Pancreas 20090501
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Effectiveness of topically applied halofuginone in management of subglottic stenosis in rats.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20090501
-
Synthesis and comparison of antimalarial activity of febrifugine derivatives including halofuginone.
Medicinal chemistry (Shariqah (United Arab Emirates)) 20090501
-
Treatment of calf diarrhea: antimicrobial and ancillary treatments.
The Veterinary clinics of North America. Food animal practice 20090301
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Halofuginone prevents extracellular matrix deposition in diabetic nephropathy.
Biochemical and biophysical research communications 20090206
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Wound-healing modulation in upper airway stenosis-Myths and facts.
Head & neck 20090101
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Anti-angiogenic effects of pterogynidine alkaloid isolated from Alchornea glandulosa.
BMC complementary and alternative medicine 20090101
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Halofuginone has a beneficial effect on gentamicin-induced acute nephrotoxicity in rats.
Drug and chemical toxicology 20090101
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Focus on collagen: in vitro systems to study fibrogenesis and antifibrosis state of the art.
Fibrogenesis & tissue repair 20090101
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Targeting liver myofibroblasts: a novel approach in anti-fibrogenic therapy.
Hepatology international 20081201
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Prevention of muscle fibrosis and improvement in muscle performance in the mdx mouse by halofuginone.
Neuromuscular disorders : NMD 20081101
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An outbreak of cryptosporidiosis in a collection of Stone curlews (Burhinus oedicnemus) in Dubai.
Avian pathology : journal of the W.V.P.A 20081001
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Myofibroblasts in pulmonary and brain metastases of alveolar soft-part sarcoma: a novel target for treatment?
Neoplasia (New York, N.Y.) 20080901
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The effect of halofuginone, a specific inhibitor of collagen type 1 synthesis, in the prevention of pancreatic fibrosis in an experimental model of severe hyperstimulation and obstruction pancreatitis.
The Journal of surgical research 20080701
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The preventive effect of halofuginone on posterior glottic stenosis in a rabbit model.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20080701
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Halofuginone upregulates the expression of heparanase in thioacetamide-induced liver fibrosis in rats.
Laboratory investigation; a journal of technical methods and pathology 20080601
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Functional resolution of fibrosis in mdx mouse dystrophic heart and skeletal muscle by halofuginone.
American journal of physiology. Heart and circulatory physiology 20080401
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Focusing on fibrosis: halofuginone-induced functional improvement in the mdx mouse model of Duchenne muscular dystrophy.
American journal of physiology. Heart and circulatory physiology 20080401
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Type I collagen expression contributes to angiogenesis and the development of deeply invasive cutaneous melanoma.
International journal of cancer 20080301
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NF-kappa B: a new player in angiostatic therapy.
Angiogenesis 20080301
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The liver pharmacological and xenobiotic gene response repertoire.
Molecular systems biology 20080101
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Effect of halofuginone lactate on treatment and prevention of lamb cryptosporidiosis: an extensive field trial.
Journal of veterinary pharmacology and therapeutics 20071201
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Involvement of ERK signaling in halofuginone-driven inhibition of fibroblast ability to contract collagen lattices.
European journal of pharmacology 20071114
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(2R,3S)-(+)- and (2S,3R)-(-)-Halofuginone lactate: synthesis, absolute configuration, and activity against Cryptosporidium parvum.
Bioorganic & medicinal chemistry letters 20070801
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Development and validation of a cell culture based assay for in vitro assessment of anticryptosporidial compounds.
Parasitology research 20070601
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Gene expression during chemically induced liver fibrosis: effect of halofuginone on TGF-beta signaling.
Cell and tissue research 20070401
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Evaluation of endotoxaemia in the prognosis and treatment of scouring merino lambs.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20070301
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Inhibition of fibroblast to myofibroblast transition by halofuginone contributes to the chemotherapy-mediated antitumoral effect.
Molecular cancer therapeutics 20070201
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Effects of halofuginone on fibrosis formation secondary to experimentally induced subglottic trauma.
The Laryngoscope 20070201
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Halofuginone reduces the occurrence of renal fibrosis in 5/6 nephrectomized rats.
The Israel Medical Association journal : IMAJ 20070101
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Potential therapeutical effects of topical halofuginone hydrobromide in keloid management.
Medical hypotheses 20070101
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Effect of halofuginone, a collagen alpha1(I) inhibitor, on wound healing in normal and irradiated skin: implication for hematopoietic stem cell transplantation.
Acta haematologica 20070101
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Evolving concepts of liver fibrogenesis provide new diagnostic and therapeutic options.
Comparative hepatology 20070101
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Field study of the efficacy of halofuginone and decoquinate in the treatment of cryptosporidiosis in veal calves.
The Veterinary record 20061111
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Hydrodynamics based transfection in normal and fibrotic rats.
World journal of gastroenterology 20061014
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Halofuginone inhibits NF-kappaB and p38 MAPK in activated T cells.
Journal of leukocyte biology 20060801
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Phase I and pharmacokinetic study of halofuginone, an oral quinazolinone derivative in patients with advanced solid tumours.
European journal of cancer (Oxford, England : 1990) 20060801
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Halofuginone induces matrix metalloproteinases in rat hepatic stellate cells via activation of p38 and NFkappaB.
The Journal of biological chemistry 20060602
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Involvement of the tyrosine phosphatase early gene of liver regeneration (PRL-1) in cell cycle and in liver regeneration and fibrosis effect of halofuginone.
Cell and tissue research 20060601
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Halofuginone prevents subglottic stenosis in a canine model.
The Annals of otology, rhinology, and laryngology 20060501
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Halofuginone suppresses the lung metastasis of chemically induced hepatocellular carcinoma in rats through MMP inhibition.
Neoplasia (New York, N.Y.) 20060401
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Halofuginone inhibits tumor growth in the polyoma middle T antigen mouse via a thrombospondin-1 independent mechanism.
Cancer biology & therapy 20060201
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Inhibition of rat renal fibroblast proliferation by halofuginone.
Nephron. Experimental nephrology 20060101
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Drug-eluting stent: a review and update.
Vascular health and risk management 20051201
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Incidence of residues of nine anticoccidials in eggs.
Food additives and contaminants 20051101
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Inhibition of Wilms tumor xenograft progression by halofuginone is accompanied by activation of WT-1 gene expression.
The Journal of urology 20051001
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Deposition and depletion of five anticoccidials in eggs.
Journal of agricultural and food chemistry 20050907
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Prevention of esophageal strictures in a caustic burn model using halofuginone, an inhibitor of collagen type I synthesis.
The Laryngoscope 20050901
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Halofuginone inhibits collagen deposition in fibrous capsules around implants.
Annals of plastic surgery 20050301
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Screening for the coccidiostats halofuginone and nicarbazin in egg and chicken muscle: development of an ELISA.
Food additives and contaminants 20050201
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Residue analysis for halofuginone in sturgeon muscle by immunoaffinity cleanup and liquid chromatography.
Journal of AOAC International 20050101
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Efficient and sensitive detection of residues of nine coccidiostats in egg and muscle by liquid chromatography-electrospray tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225
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Examination of antimicrobial activity of selected non-antibiotic drugs.
Acta poloniae pharmaceutica 20041201
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Animal models of systemic sclerosis: insights into systemic sclerosis pathogenesis and potential therapeutic approaches.
Current opinion in rheumatology 20041101
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Liquid chromatography-electrospray tandem mass spectrometric assay suitable for quantitation of halofuginone in plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041015
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Halofuginone can worsen liver fibrosis in bile duct obstructed rats.
Liver international : official journal of the International Association for the Study of the Liver 20041001
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Halofuginone inhibits angiogenesis and growth in implanted metastatic rat brain tumor model--an MRI study.
Neoplasia (New York, N.Y.) 20040901
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Suppression of hepatocellular carcinoma growth in mice by the alkaloid coccidiostat halofuginone.
European journal of cancer (Oxford, England : 1990) 20040601
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Ureteral replacement using small-intestinal submucosa and a collagen inhibitor in a porcine model.
Journal of endourology 20040601
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Potential nonhormonal therapeutics for medical treatment of leiomyomas.
Seminars in reproductive medicine 20040501
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Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone.
The Journal of biological chemistry 20040409
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Smad3 as a mediator of the fibrotic response.
International journal of experimental pathology 20040401
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Halofuginone, an inhibitor of collagen synthesis by rat stellate cells, stimulates insulin-like growth factor binding protein-1 synthesis by hepatocytes.
Journal of hepatology 20040201
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The effect of halofuginone, a specific inhibitor of collagen type 1 synthesis, in the prevention of esophageal strictures related to caustic injury.
American journal of surgery 20040201
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Determination of halofuginone in eggs by liquid chromatography/tandem mass spectrometry after cleanup with immunoaffinity chromatography.
Rapid communications in mass spectrometry : RCM 20040101
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Halofuginone inhibits serum-stimulated pericardial tissue retraction in vitro.
Tissue engineering 20040101
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The use of halofuginone in limiting urethral stricture formation and recurrence: an experimental study in rabbits.
The Journal of urology 20031101
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Treatment with halofuginone results in marked growth inhibition of a von Hippel-Lindau pheochromocytoma in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 20030901
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Resistance to anticoccidial drugs of Dutch avian Eimeria spp. field isolates originating from 1996, 1999 and 2001.
Avian pathology : journal of the W.V.P.A 20030801
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Halofuginone to treat fibrosis in chronic graft-versus-host disease and scleroderma.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20030701
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Development and validation of a method for the confirmation of halofuginone in chicken liver and eggs using electrospray tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030505
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The production and characterisation of an antibody to detect the coccidiostat toltrazuril and its metabolite ponazuril.
The Analyst 20030501
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A medical compound derived from herbs.
Science (New York, N.Y.) 20030328
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Prevalence and control of bovine cryptosporidiosis in German dairy herds.
Veterinary parasitology 20030325
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Hepatitis C and liver fibrosis.
Cell death and differentiation 20030101
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Hepatic fibrosis: from bench to bedside.
Journal of gastroenterology and hepatology 20021201
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Halofuginone inhibition of COL1A2 promoter activity via a c-Jun-dependent mechanism.
Arthritis and rheumatism 20021001
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Halofuginone, a collagen type I inhibitor improves liver regeneration in cirrhotic rats.
Journal of hepatology 20020901
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Halofuginone does not reduce fibrosis in bleomycin-induced lung injury.
Life sciences 20020823
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Effect of halofuginone on the development of tight skin (TSK) syndrome.
Autoimmunity 20020701
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Angiogenesis in bladder cancer--prognostic marker and target for future therapy.
Surgical oncology 20020601
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The production and characterisation of dinitrocarbanilide antibodies raised using antigen mimics.
Journal of immunological methods 20020601
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Growth inhibition of prostate cancer xenografts by halofuginone.
The Prostate 20020501
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Analysis of the effect of halofuginone on bleomycin-induced scleroderma.
Rheumatology (Oxford, England) 20020501
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Halofuginone, an inhibitor of type-I collagen synthesis and skin sclerosis, blocks transforming-growth-factor-beta-mediated Smad3 activation in fibroblasts.
The Journal of investigative dermatology 20020301
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Inhibition of anastomotic intimal hyperplasia by a synthetic nonsulphated heparin-mimicking compound.
Experimental and clinical cardiology 20020101
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Reduction in dermal fibrosis in the tight-skin (Tsk) mouse after local application of halofuginone.
Biochemical pharmacology 20011101
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Pharmacokinetics and tissue distribution of halofuginone (NSC 713205) in CD2F1 mice and Fischer 344 rats.
Cancer chemotherapy and pharmacology 20011101
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Halofuginone to prevent and treat thioacetamide-induced liver fibrosis in rats.
Hepatology (Baltimore, Md.) 20010201
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Novel therapy in the treatment of scleroderma.
Expert opinion on investigational drugs 20010101
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Determination of halofuginone and amprolium in chicken muscle and egg by liquid chromatography.
Journal of AOAC International 20010101
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Halofuginone: a potent inhibitor of critical steps in angiogenesis progression.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20001201
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The activity of halofuginone in immunosuppressed rats infected with Cryptosporidium parvum.
The Journal of antimicrobial chemotherapy 19950301