56341-39-0 | 6-Fluorooxindole

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$14.00	$10.00
1g	97%	in stock	$20.00	$14.00
5g	97%	in stock	$22.00	$16.00
10g	97%	in stock	$43.00	$31.00

Description

• Catalog Number: AI52652
• Chemical Name: 6-Fluorooxindole
• CAS Number: 56341-39-0
• Molecular Formula: C8H6FNO
• Molecular Weight: 151.1377
• MDL Number: MFCD00047212
• SMILES: O=C1Cc2c(N1)cc(cc2)F

Computed Properties

• Complexity: 183
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: 1.3

Upstream Synthesis Route

6-Fluoroindolin-2-one is a versatile organic compound that finds wide applications in chemical synthesis, particularly in the field of medicinal and pharmaceutical chemistry. This compound serves as a key building block in the synthesis of various biologically active molecules and pharmaceuticals due to its unique structure and reactivity.One of the main applications of 6-Fluoroindolin-2-one is as a synthon for the construction of heterocyclic compounds. Its fluorinated moiety imparts specific properties to the resulting molecules, making them potential candidates for drug development. By utilizing 6-Fluoroindolin-2-one as a starting material, chemists can access a diverse range of complex structures through various synthetic strategies such as cyclization reactions, functional group manipulations, and cross-coupling reactions.Moreover, the presence of the indolin-2-one scaffold in 6-Fluoroindolin-2-one offers a platform for further derivatization, allowing for the introduction of different functional groups or modifications to tailor the physicochemical and biological properties of the final compounds. This flexibility in structural modification makes 6-Fluoroindolin-2-one a valuable tool in the design and synthesis of novel drug candidates with enhanced pharmacological profiles.Overall, the application of 6-Fluoroindolin-2-one in chemical synthesis opens up possibilities for the creation of diverse molecular structures with potential applications in drug discovery, agrochemicals, and materials science. Its role as a key intermediate highlights its importance in the development of new bioactive compounds and underscores its significance in modern organic synthesis methodologies.

Literature

• Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase.

  Journal of medicinal chemistry 20110113