56839-43-1 | 1-(4-ethylphenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one hydrochloride

Packsize	Purity	Availability	Price	Discounted Price
1g	98%(HPLC)	in stock	$27.00	$19.00
5g	97%	in stock	$82.00	$58.00
25g	97%	in stock	$251.00	$176.00
100g	97%	in stock	$636.00	$445.00

Description

• Catalog Number: AI52736
• Chemical Name: 1-(4-ethylphenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one hydrochloride
• CAS Number: 56839-43-1
• Molecular Formula: C17H26ClNO
• Molecular Weight: 295.8474
• MDL Number: MFCD00941459
• SMILES: CCc1ccc(cc1)C(=O)C(CN1CCCCC1)C.Cl

Computed Properties

• Complexity: 275
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 5
• Undefined Atom Stereocenter Count: 1

Literature

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  Yonsei medical journal 20120701

• Eperisone versus tizanidine for treatment of chronic low back pain.

  Minerva medica 20120601

• Reduction of tinnitus severity by the centrally acting muscle relaxant cyclobenzaprine: an open-label pilot study.

  Audiology & neuro-otology 20120101

• Enantioselective carbonyl reduction of eperisone in human liver microsomes.

  Xenobiotica; the fate of foreign compounds in biological systems 20110901

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  Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20110901

• Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

  Journal of medicinal chemistry 20110714

• A case of torsades de pointes induced by severe QT prolongation after an overdose of eperisone and triazolam in a patient receiving nifedipine.

  Clinical toxicology (Philadelphia, Pa.) 20100201

• Efficacy and tolerability of eperisone and baclofen in spastic palsy: a double-blind randomized trial.

  Advances in therapy 20090501

• Efficacy and safety of eperisone in patients with low back pain: a double blind randomized study.

  European review for medical and pharmacological sciences 20080101

• Determination of eperisone in human plasma by liquid chromatography-ESI-tandem mass spectrometry.

  Archives of pharmacal research 20070901

• Antinociceptive effects of sodium channel-blocking agents on acute pain in mice.

  Journal of pharmacological sciences 20040601

• [Pharmacokinetics and bioequivalence of eperisone hydrochloride tablet in healthy subjects].

  Yao xue xue bao = Acta pharmaceutica Sinica 20040401

• Rapid and sensitive liquid chromatography-electrospray ionization-mass spectrometry method for the determination of eperisone in human plasma: method and clinical applications.

  Journal of chromatographic science 20040101

• Separation of basic drug enantiomers by capillary electrophoresis using chicken alpha1-acid glycoprotein: insight into chiral recognition mechanism.

  Electrophoresis 20030801

• A protein-encapsulation technique by the sol-gel method for the preparation of monolithic columns for capillary electrochromatography.

  Analytical chemistry 20020415

• Intestinal first-pass metabolism of eperisone in the rat.

  Pharmaceutical research 20010801

• Treatment of tardive dystonia with an antispastic agent.

  Acta psychiatrica Scandinavica 19981001