571-60-8 | 1,4-Dihydroxynaphthalene

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$23.00	$16.00
1g	98%	in stock	$25.00	$18.00
5g	98%	in stock	$65.00	$46.00
25g	98%	in stock	$115.00	$80.00

Description

• Catalog Number: AB77000
• Chemical Name: 1,4-Dihydroxynaphthalene
• CAS Number: 571-60-8
• Molecular Formula: C10H8O2
• Molecular Weight: 160.1693
• MDL Number: MFCD00003977
• SMILES: Oc1ccc(c2c1cccc2)O

Computed Properties

• Complexity: 140
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• XLogP3: 1.8

Literature

• A laccase-catalysed one-pot synthesis of aminonaphthoquinones and their anticancer activity.

  Bioorganic & medicinal chemistry 20120715

• Three different dimerizations of 2-bromo-3-methyl-1,4-naphthoquinones.

  The Journal of organic chemistry 20120518

• Discovery and synthesis of hydronaphthoquinones as novel proteasome inhibitors.

  Journal of medicinal chemistry 20120308

• Rational design of indoleamine 2,3-dioxygenase inhibitors.

  Journal of medicinal chemistry 20100211

• Naphthoquinones and anthraquinones from scent glands of a dyspnoid Harvestman, Paranemastoma quadripunctatum.

  Journal of chemical ecology 20100201

• N-Heterocyclic carbene-catalyzed monoacylation of 1,4-naphthoquinones with aldehydes.

  The Journal of organic chemistry 20091218

• 5-Amino-1-naphthol: two-dimensional sheets built up from R(4)(4)(18) rings formed by O-H...N, N-H...O and pi-pi interactions.

  Acta crystallographica. Section C, Crystal structure communications 20091101

• Synthesis and cytotoxic evaluation of 6-(3-pyrazolylpropyl) derivatives of 1,4-naphthohydroquinone-1,4-diacetate.

  Archiv der Pharmazie 20091001

• Pivotal role for two electron reduction in 2,3-dimethoxy-1,4-naphthoquinone and 2-methyl-1,4-naphthoquinone metabolism and kinetics in vivo that prevents liver redox stress.

  Chemical research in toxicology 20090401

• 2,3-Disubstituted-1,4-naphthoquinones, 12H-benzo[b]phenothiazine-6,11-diones and related compounds: synthesis and biological evaluation as potential antiproliferative and antifungal agents.

  European journal of medicinal chemistry 20090301

• Ascomycones A-C, heptaketide metabolites from an unidentified ascomycete.

  Journal of natural products 20081101

• Diastereoselective and enantioselective reduction of tetralin-1,4-dione.

  Beilstein journal of organic chemistry 20080101

• Disparity in the induction of glutathione depletion, ROS formation, poly(ADP-ribose) polymerase-1 activation, and apoptosis by quinonoid derivatives of naphthalene in human cultured cells.

  Chemico-biological interactions 20070220

• Selective antiproliferative activity of hydroxynaphthyl-beta-D-xylosides.

  Journal of medicinal chemistry 20060323

• Rediscovery, isolation, and asymmetric reduction of 1,2,3,4-tetrahydronaphthalene-1,4-dione and studies of its [Cr(CO)3] complex.

  Angewandte Chemie (International ed. in English) 20051216

• Determination of dihydroxynaphthalenes in human urine by gas chromatography-mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051105

• Effects of naphthalene quinonoids on the induction of oxidative DNA damage and cytotoxicity in calf thymus DNA and in human cultured cells.

  Chemical research in toxicology 20050801

• Effects of static and dynamic perturbations on isotropic hyperfine coupling constants in some quinone radicals.

  Magnetic resonance in chemistry : MRC 20050301

• Desymmetrization of a meso-diol complex derived from [Cr(CO)3(eta6-5,8-naphthoquinone)]: use of new diamine acylation catalysts.

  Chemical communications (Cambridge, England) 20040707

• Phototransformation of 1,4-naphthoquinone in aqueous solution.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20031001

• A cytotoxic butenolide, two new dolabellane diterpenoids, a chroman and a benzoquinol derivative formosan Casearia membranacea.

  Planta medica 20030701

• Formation of benzoquinol moiety in cornoside by salidroside mono-oxygenase, a cytochrome P450 enzyme, from Abeliophyllum distichumcell suspension cultures.

  Planta 20030101

• Interaction of aromatic compounds with Photobacterium leiognathi luciferase: fluorescence anisotropy study.

  Luminescence : the journal of biological and chemical luminescence 20030101

• Nepenthes insignis uses a C2-portion of the carbon skeleton of L-alanine acquired via its carnivorous organs, to build up the allelochemical plumbagin.

  Phytochemistry 20020301

• Inactivation of rat cytochrome P450 2D enzyme by a further metabolite of 4-hydroxypropranolol, the major and active metabolite of propranolol.

  Biological & pharmaceutical bulletin 20010901

• Selective nonpeptidic inhibitors of herpes simplex virus type 1 and human cytomegalovirus proteases.

  Biological & pharmaceutical bulletin 20010301