58306-30-2 | Febantel

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$15.00	$10.00
1g	98+%	in stock	$15.00	$11.00
5g	98%(HPLC)	in stock	$39.00	$27.00
25g	98%(HPLC)	in stock	$83.00	$59.00
100g	98%(HPLC)	in stock	$248.00	$174.00

Description

• Catalog Number: AI53051
• Chemical Name: Febantel
• CAS Number: 58306-30-2
• Molecular Formula: C20H22N4O6S
• Molecular Weight: 446.4769
• MDL Number: MFCD01738527
• SMILES: COCC(=O)Nc1cc(ccc1NC(=NC(=O)OC)NC(=O)OC)Sc1ccccc1

Computed Properties

• Complexity: 621
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 31
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 10
• XLogP3: 3.8

Literature

• Why are most phospholipidosis inducers also hERG blockers?

  Archives of toxicology 20171201

• Optimization of matrix solid-phase dispersion for liquid chromatography tandem mass spectrometry analysis of 12 pharmaceuticals in sediments.

  Journal of chromatography. A 20121005

• Methyl N-({[2-(2-meth-oxy-acetamido)-4-(phenyl-sulfan-yl)phen-yl]amino}[(meth-oxy-carbonyl)imino]methyl)carbamate.

  Acta crystallographica. Section E, Structure reports online 20120301

• Efficiency of RO/NF membranes at the removal of veterinary antibiotics.

  Water science and technology : a journal of the International Association on Water Pollution Research 20120101

• Potential drug development candidates for human soil-transmitted helminthiases.

  PLoS neglected tropical diseases 20110601

• Are we paying too much attention to cardio-pulmonary nematodes and neglecting old-fashioned worms like Trichuris vulpis?

  Parasites & vectors 20110101

• Effect of water matrices on removal of veterinary pharmaceuticals by nanofiltration and reverse osmosis membranes.

  Journal of environmental sciences (China) 20110101

• Determination of multi-class pharmaceuticals in wastewater by liquid chromatography-tandem mass spectrometry (LC-MS-MS).

  Analytical and bioanalytical chemistry 20101001

• Efficacy of a combination product containing pyrantel, febantel and praziquantel (Drontal Plus Flavour, Bayer Animal Health) against experimental infection with the hookworm Ancylostoma ceylanicum in dogs.

  Parasitology research 20100101

• Canine and feline cardiopulmonary parasitic nematodes in Europe: emerging and underestimated.

  Parasites & vectors 20100101

• Determination of active substances in multicomponent veterinary preparations of antiparasitic action by HPLC method.

  Acta poloniae pharmaceutica 20100101

• Treatment of naturally occurring, asymptomatic Giardia sp. in dogs with Drontal Plus flavour tablets.

  Parasitology research 20090801

• Synergistic effect of febantel and pyrantel embonate in elimination of Giardia in a gerbil model.

  Parasitology research 20090801

• Anthelmintic efficacy on Parascaris equorum in foals on Swedish studs.

  Acta veterinaria Scandinavica 20090101

• Highly pathogenic avian influenza virus (H5N1) infection in red foxes fed infected bird carcasses.

  Emerging infectious diseases 20081201

• Efficacy of Drontal Flavour Plus (50 mg praziquantel, 144 mg pyrantel embonate, 150 mg febantel per tablet) against Giardia sp in naturally infected dogs.

  Parasitology research 20081001

• UMF-078: A modified flubendazole with potent macrofilaricidal activity against Onchocerca ochengi in African cattle.

  Parasites & vectors 20080101

• First report of multiple drug resistance in trichostrongyles affecting sheep under field conditions in Italy.

  Parasitology research 20071101

• Survey of intestinal parasites in stray dogs in the Madrid area and comparison of the efficacy of three anthelmintics in naturally infected dogs.

  Parasitology research 20070101

• Ecological hazard assessment of major veterinary benzimidazoles: acute and chronic toxicities to aquatic microbes and invertebrates.

  Environmental toxicology and chemistry 20060801

• Comparative effects of milbemycin oxime-based and febantel-pyrantel embonate-based anthelmintic tablets on Toxocara canis egg shedding in naturally infected pups.

  Veterinary parasitology 20060430

• Coprological study on intestinal helminths in Swiss dogs: temporal aspects of anthelminthic treatment.

  Parasitology research 20060301

• Efficacy of a combination of febantel, pyrantel, and praziquantel for the treatment of kittens experimentally infected with Giardia species.

  Journal of feline medicine and surgery 20060201

• Rapid determination of the antiparasitic drugs flubendazole and febantel in feeds by HPLC with ultraviolet detection.

  Journal of pharmaceutical and biomedical analysis 20050615

• Clinical signs, diagnosis and treatment of three dogs with angiostrongylosis in Ireland.

  Irish veterinary journal 20040101

• Comparative efficacy of flubendazole chewable tablets and a tablet combination of febantel, pyrantel embonate and praziquantel against Trichuris vulpis in experimentally infected dogs.

  DTW. Deutsche tierarztliche Wochenschrift 20031001

• A light and electron microscopic study on the synergistic effect of pyrantel and the febantel metabolite febendazole on adult Toxocara canis in vitro.

  Parasitology research 20030701

• Synergistic effects of pyrantel and the febantel metabolite fenbendazole on adult Toxocara canis.

  Parasitology research 20030701

• Development and validation of a liquid chromatographic-electrospray tandem mass spectrometric multiresidue method for anthelmintics in milk.

  Journal of chromatography. A 20021108

• Efficacy of pyrantel embonate, febantel and praziquantel against Giardia species in naturally infected adult dogs.

  The Veterinary record 20020209

• Efficacy of a combination febantel-praziquantel-pyrantel product, with or without vaccination with a commercial Giardia vaccine, for treatment of dogs with naturally occurring giardiasis.

  Journal of the American Veterinary Medical Association 20020201

• Worm control practices of pig farmers in Greece.

  Veterinary parasitology 20010628

• Housing, feeding and management of calves and replacement heifers in Swedish dairy herds.

  Acta veterinaria Scandinavica 20010101

• Reaction of acidified nitrite solutions with peptide derivatives: evidence for nitrosamine and thionitrite formation from 15N N.m.r. studies.

  Journal of the Chemical Society. Perkin transactions 1 19750101