58579-51-4 | Anagrelide hydrochloride

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$12.00	$9.00
10mg	98%	in stock	$53.00	$37.00
50mg	98%	in stock	$117.00	$82.00

Description

• Catalog Number: AI53100
• Chemical Name: Anagrelide hydrochloride
• CAS Number: 58579-51-4
• Molecular Formula: C10H8Cl3N3O
• Molecular Weight: 292.5490
• MDL Number: MFCD01720337
• SMILES: O=C1N=C2N(C1)Cc1c(N2)ccc(c1Cl)Cl.Cl

Computed Properties

• Complexity: 360
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2

Literature

• Anagrelide represses GATA-1 and FOG-1 expression without interfering with thrombopoietin receptor signal transduction.

  Journal of thrombosis and haemostasis : JTH 20101001

• Essential thrombocythemia: past and present.

  Internal and emergency medicine 20091001

• [Primary thrombocythemia: diagnosis and therapy].

  Medizinische Klinik (Munich, Germany : 1983) 20060815

• Molecular basis of the diagnosis and treatment of polycythemia vera and essential thrombocythemia.

  Blood 20060601

• Anagrelide: a review of its use in the management of essential thrombocythaemia.

  Drugs 20060101

• Polycythaemia vera and essential thrombocythaemia: current treatment strategies.

  Drugs 20060101

• Primary and secondary thrombocytosis in childhood.

  British journal of haematology 20050401

• PDGF-A, PDGF-B, TGFbeta, and bFGF mRNA levels in patients with essential thrombocythemia treated with anagrelide.

  American journal of hematology 20050201

• Anagrelide-associated cardiomyopathy in polycythemia vera and essential thrombocythemia.

  Haematologica 20041101

• [Ulcers on the legs and feet: a seldom recognised side effect of hydroxyurea].

  Nederlands tijdschrift voor geneeskunde 20030802

• Anagrelide-induced cardiomyopathy.

  Pharmacotherapy 20001001