5875-06-9 | Proparacaine, HCl

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$16.00	$11.00
25mg	98%	in stock	$20.00	$14.00
100mg	98%	in stock	$29.00	$20.00
250mg	98%	in stock	$45.00	$31.00
500mg	98%	in stock	$45.00	$32.00
1g	98%	in stock	$78.00	$54.00
5g	98%	in stock	$254.00	$178.00

Description

• Catalog Number: AI53147
• Chemical Name: Proparacaine, HCl
• CAS Number: 5875-06-9
• Molecular Formula: C16H27ClN2O3
• Molecular Weight: 330.8502
• MDL Number: MFCD00083467
• SMILES: CCCOc1ccc(cc1N)C(=O)OCCN(CC)CC.Cl
• NSC Number: 759896

Computed Properties

• Complexity: 295
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 22
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 10

Literature

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  International ophthalmology 20120601

• Factors affecting patients' pain intensity during in office intravitreal injection procedure.

  Retina (Philadelphia, Pa.) 20120401

• Randomized double-masked controlled trial comparing pain scores with and without the use of supplementary 2% lidocaine gel in LASIK.

  American journal of ophthalmology 20120401

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  The Cochrane database of systematic reviews 20110907

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  Veterinary ophthalmology 20110901

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  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20110601

• Effect of a proparacaine 0.50%-sodium fluorescein 0.25% mix and contact ultrasound pachymetry on central and midperipheral corneal thickness measured by noncontact optical pachymetry.

  Journal of cataract and refractive surgery 20110501

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  Journal of perinatology : official journal of the California Perinatal Association 20101101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

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  CJEM 20100901

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  Journal of the Formosan Medical Association = Taiwan yi zhi 20091201

• Proparacaine complexation with beta-cyclodextrin and p-sulfonic acid calix[6]arene, as evaluated by varied (1)H-NMR approaches.

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• Topical proparacaine and episcleral venous pressure in the rabbit.

  Investigative ophthalmology & visual science 20090601

• Intrathecal oxybuprocaine and proxymetacaine produced potent and long-lasting spinal anesthesia in rats.

  Neuroscience letters 20090501

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  American journal of ophthalmology 20090201

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  Cornea 20090101

• An atypical presentation of acanthamoeba keratitis in a patient with keratoconus treated briefly with topical anesthetic.

  Eye & contact lens 20090101

• Comparative study of analgesic effectiveness using three different anesthetic techniques for intravitreal injection of bevacizumab.

  Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 20090101

• Adjustable suture strabismus surgery in infants and children.

  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20081201

• Evaluation of duration of corneal anesthesia induced with ophthalmic 0.5% proparacaine hydrochloride by use of a Cochet-Bonnet aesthesiometer in clinically normal horses.

  American journal of veterinary research 20081201

• Neuroprotective effect of intravitreal triamcinolone acetonide against photoreceptor apoptosis in a rabbit model of subretinal hemorrhage.

  Investigative ophthalmology & visual science 20080901

• Topology of a ternary complex (proparacaine-beta-cyclodextrin-liposome) by STD NMR.

  Magnetic resonance in chemistry : MRC 20080901

• A lacrimal sac abscess incision and drainage technique.

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  Journal of pediatric ophthalmology and strabismus 20080101

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• An assessment of the discomfort associated with the use of rose bengal 1% eyedrops on the normal human eye: a comparison with saline 0.9% and a topical ocular anaesthetic.

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• Effect of proparacaine on central corneal thickness values: an evaluation using noncontact specular microscopy and pentacam.

  Cornea 20070101

• Assessment of bacterial contamination of three multidose ophthalmic solutions.

  Veterinary ophthalmology 20070101

• Phacoemulsification in vitrectomized eyes under topical anesthesia.

  European journal of ophthalmology 20070101

• Duration of corneal anesthesia following topical administration of 0.5% proparacaine hydrochloride solution in clinically normal cats.

  American journal of veterinary research 20061001

• Prospective randomized double-masked trial to evaluate perioperative pain profile in different stages of simultaneous bilateral LASIK.

  Cornea 20060901

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  Cornea 20060101

• Anaesthetic abuse keratopathy as a manifestation of ocular Munchausen's syndrome.

  Clinical & experimental ophthalmology 20060101

• Subtenon lidocaine vs topical proparacaine in adult strabismus surgery.

  Annals of ophthalmology (Skokie, Ill.) 20060101

• Patient pain during stretching of small pupils in phacoemulsification performed using topical anesthesia.

  Journal of cataract and refractive surgery 20050901

• Efficacy of sucrose to reduce pain in premature infants during eye examinations for retinopathy of prematurity.

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  The Annals of pharmacotherapy 20050501

• Flap suturing with proparacaine for recurrent epithelial ingrowth following laser in situ keratomileusis surgery.

  Journal of cataract and refractive surgery 20050501

• Randomised controlled trial of sub-Tenon's block versus topical anaesthesia for cataract surgery: a comparison of patient satisfaction.

  The British journal of ophthalmology 20050301

• Duration of effect and effect of multiple doses of topical ophthalmic 0.5% proparacaine hydrochloride in clinically normal dogs.

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• Epithelial activity of hexokinase and glucose-6-phosphate dehydrogenase in cultured bovine lenses recovering from pharmaceutical-induced optical damage.

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• The local anesthetic proparacaine modifies sodium transport in toad skin and perturbs the structures of model and cell membranes.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101

• Allergic contact dermatitis to proparacaine with subsequent cross-sensitization to tetracaine from ophthalmic preparations.

  American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20010901

• The efficacy of 0.5% proparacaine stored at room temperature.

  Veterinary ophthalmology 20010901

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  The British journal of ophthalmology 20010401

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  American journal of veterinary research 19980401