60719-84-8 | Amrinone

Packsize	Purity	Availability	Price	Discounted Price
1mg	99%	in stock	$7.00	$5.00
250mg	99%	in stock	$20.00	$14.00
1g	99%	in stock	$59.00	$41.00
10g	99%	in stock	$306.00	$214.00

Description

• Catalog Number: AI53524
• Chemical Name: Amrinone
• CAS Number: 60719-84-8
• Molecular Formula: C10H9N3O
• Molecular Weight: 187.1980
• MDL Number: MFCD00083228
• SMILES: O=c1[nH]cc(cc1N)c1ccncc1
• NSC Number: 759805

Computed Properties

• Complexity: 301
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: -0.2

Literature

• Phosphodiesterase-III Inhibitors Amrinone and Milrinone on Epilepsy and Cardiovascular Activities.

  North American journal of medical sciences 20121001

• Synthesis and evaluation of novel 2-pyridone derivatives as inhibitors of phosphodiesterase3 (PDE3): a target for heart failure and platelet aggregation.

  Bioorganic & medicinal chemistry letters 20120915

• Clinical features and management outcomes of severe hand, foot and mouth disease.

  Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20120101

• Identification of common biological pathways and drug targets across multiple respiratory viruses based on human host gene expression analysis.

  PloS one 20120101

• Cardiac ryanodine receptor in metabolic syndrome: is JTV519 (K201) future therapy?

  Diabetes, metabolic syndrome and obesity : targets and therapy 20120101

• Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

  PLoS computational biology 20111201

• Discovery and structure-activity relationship of 3-aminopyrid-2-ones as potent and selective interleukin-2 inducible T-cell kinase (Itk) inhibitors.

  Journal of medicinal chemistry 20110414

• Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.

  Drug metabolism and disposition: the biological fate of chemicals 20110201

• Suppressive effect of juzen-taiho-to on lung metastasis of b16 melanoma cells in vivo.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• Case report and mini literature review: anesthetic management for severe peripartum cardiomyopathy complicated with preeclampsia using sufetanil in combined spinal epidural anesthesia.

  Yonsei medical journal 20110101

• The challenge to verify ceramide's role of apoptosis induction in human cardiomyocytes--a pilot study.

  Journal of cardiothoracic surgery 20110101

• Hydrogen sulfide attenuated tumor necrosis factor-α-induced inflammatory signaling and dysfunction in vascular endothelial cells.

  PloS one 20110101

• Prolonged Refractory Hypotension following Combined Amlodipine and Losartan Ingestion Responsive to Metaraminol.

  Case reports in medicine 20110101

• No relevant cardiac, pharmacokinetic or safety interactions between roflumilast and inhaled formoterol in healthy subjects: an open-label, randomised, actively controlled study.

  BMC clinical pharmacology 20110101

• Biopsy-Proven Acute Tubular Necrosis due to Vancomycin Toxicity.

  International journal of nephrology 20110101

• Infrared assisted production of 3,4-dihydro-2(1H)-pyridones in solvent-free conditions.

  International journal of molecular sciences 20110101

• Genome-wide assessment for genetic variants associated with ventricular dysfunction after primary coronary artery bypass graft surgery.

  PloS one 20110101

• A case report and brief review of the literature on bilateral retinal infarction following cardiopulmonary bypass for coronary artery bypass grafting.

  Journal of cardiothoracic surgery 20110101

• A predictive ligand-based Bayesian model for human drug-induced liver injury.

  Drug metabolism and disposition: the biological fate of chemicals 20101201

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• A phosphodiesterase III inhibitor protects rat liver from sinusoidal obstruction syndrome through heme oxygenase-1 induction.

  Annals of surgery 20100401

• Human cardiac tissue in a microperfusion chamber simulating extracorporeal circulation--ischemia and apoptosis studies.

  Journal of cardiothoracic surgery 20100101

• Clinical review: practical recommendations on the management of perioperative heart failure in cardiac surgery.

  Critical care (London, England) 20100101

• Pulmonary vascular and right ventricular dysfunction in adult critical care: current and emerging options for management: a systematic literature review.

  Critical care (London, England) 20100101

• Agents with inotropic properties for the management of acute heart failure syndromes. Traditional agents and beyond.

  Heart failure reviews 20091201

• Pharmacological interventions versus no pharmacological intervention for ischaemia reperfusion injury in liver resection surgery performed under vascular control.

  The Cochrane database of systematic reviews 20091007

• Pharmacological interventions for ischaemia reperfusion injury in liver resection surgery performed under vascular control.

  The Cochrane database of systematic reviews 20091007

• Myocardial cyclic AMP augmentation with high-dose PDEIII inhibitor in terminal warm blood cardioplegia.

  Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 20091001

• Drug effect unveils inter-head cooperativity and strain-dependent ADP release in fast skeletal actomyosin.

  The Journal of biological chemistry 20090821

• Design, synthesis and pharmacological evaluation of 6-hydroxy-4-methylquinolin-2(1H)-one derivatives as inotropic agents.

  Journal of enzyme inhibition and medicinal chemistry 20090801

• Anticancer Chemotherapy and it's Anaesthetic Implications (Current Concepts).

  Indian journal of anaesthesia 20090201

• Effects of amrinone in an experimental model of hepatic ischemia-reperfusion injury.

  The Journal of surgical research 20090101

• Gene expression analysis reveals new possible mechanisms of vancomycin-induced nephrotoxicity and identifies gene markers candidates.

  Toxicological sciences : an official journal of the Society of Toxicology 20090101

• Effect of nitric oxide/cyclic guanosine mono-phosphate pathway on gallbladder relaxant response in bile duct-ligated guinea pigs.

  European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20090101

• Vesnarinone represses the fibrotic changes in murine lung injury induced by bleomycin.

  International journal of biological sciences 20090101

• The role of phosphodiesterase 3 in endotoxin-induced acute kidney injury.

  BMC infectious diseases 20090101

• Effects of propofol on responses of rat isolated renal arteriole to vasoactive agents.

  Vascular pharmacology 20090101

• Evaluation of preoperative intra-aortic balloon pump in coronary patients with severe left ventricular dysfunction undergoing OPCAB surgery: early and mid-term outcomes.

  Journal of cardiothoracic surgery 20090101

• Tadalafil in the treatment of erectile dysfunction.

  Therapeutics and clinical risk management 20081201

• The base exchange reaction of NAD+ glycohydrolase: identification of novel heterocyclic alternative substrates.

  Archives of biochemistry and biophysics 20081115

• Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

  Journal of medicinal chemistry 20081113

• Inotropic and chronotropic effects of 6-hydroxy-4-methylquinolin-2(1H)-one derivatives in isolated rat atria.

  Iranian biomedical journal 20080401

• Comparison of the initial hospitalization costs between the patients treated with dobutamine and the patients treated with amrinone for acute decompensated heart failure in a Japanese institute.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20080301

• Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008.

  Intensive care medicine 20080101

• Labetalol infusion for refractory hypertension causing severe hypotension and bradycardia: an issue of patient safety.

  Patient safety in surgery 20080101

• Peripartum cardiomyopathy: review of the literature.

  Yonsei medical journal 20071031

• [Protection of amrinone against lung injury induced by ischemia/reperfusion in rats].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20070601

• Investigation of binding proteins for anti-platelet agent K-134 by Drug-Western method.

  Biochemical and biophysical research communications 20070223

• Effects of phosphodiesterase (PDE) inhibitors on human ether-a-go-go related gene (hERG) channel activity.

  Journal of applied toxicology : JAT 20070101

• Cirrhotic cardiomyopathy.

  Orphanet journal of rare diseases 20070101

• Acute heart failure: inotropic agents and their clinical uses.

  Expert opinion on pharmacotherapy 20061101

• Treatment of poisoning caused by beta-adrenergic and calcium-channel blockers.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20061001

• Proper use of phosphodiesterase inhibitors according to the situations.

  Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists 20060901

• A comparison of three phosphodiesterase type III inhibitors on mechanical and metabolic function in guinea pig isolated hearts.

  Anesthesia and analgesia 20060601

• Effect of combining phosphodiesterase III inhibitors with St Thomas Hospital's solution used as transplantation preservative solution in isolated rat hearts.

  Transplantation proceedings 20060601

• Alkaline Phosphatases : Structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes.

  Purinergic signalling 20060601

• Contractile responses to selective phosphodiesterase inhibitors following chronic beta-adrenoreceptor activation.

  Pflugers Archiv : European journal of physiology 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• The effect of amrinone on liver regeneration in experimental hepatic resection model.

  The Journal of surgical research 20060101

• In vivo dilatation of the fetal and postnatal ductus arteriosus by inhibition of phosphodiesterase 3 in rats.

  Biology of the neonate 20060101

• Bench-to-bedside review: hyperinsulinaemia/euglycaemia therapy in the management of overdose of calcium-channel blockers.

  Critical care (London, England) 20060101

• Bench-to-bedside review: thrombocytopenia-associated multiple organ failure--a newly appreciated syndrome in the critically ill.

  Critical care (London, England) 20060101

• Coronary bypass grafting using crossclamp fibrillation does not result in reliable reperfusion of the myocardium when the crossclamp is intermittently released: a prospective cohort study.

  Journal of cardiothoracic surgery 20060101

• [Current approaches to intraoperative diagnosis and treatment of low cardiac output during cardiosurgical operations].

  Anesteziologiia i reanimatologiia 20060101

• Effects of a phosphodiesterase 3 inhibitor, olprinone, on rhythmical change in tension of human gastroepiploic artery.

  European journal of pharmacology 20051228

• Protective effects of different antioxidants and amrinone on vancomycin-induced nephrotoxicity.

  Basic & clinical pharmacology & toxicology 20051101

• Differential pharmacologic sensitivities of phosphodiesterase-3 inhibitors among human isolated gastroepiploic, internal mammary, and radial arteries.

  Anesthesia and analgesia 20051001

• Effects of inotropic drugs on mechanical function and oxygen balance in postischemic canine myocardium: comparison of dobutamine, epinephrine, amrinone, and calcium chloride.

  Journal of Korean medical science 20051001

• Effect of amrinone on mucosal permeability in experimental intestinal ischaemia/reperfusion injury.

  ANZ journal of surgery 20050701

• A sensitive and specific high performance liquid chromatographic assay for milrinone in rat and human plasma using a commercially available internal standard and low sample volume.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20050624

• The impact of slow rewarming on inotropy, tissue metabolism, and 'after drop' of body temperature in pediatric patients.

  The journal of extra-corporeal technology 20050601

• Inotropic responses to phosphodiesterase inhibitors in cardiac hypertrophy in rats.

  European journal of pharmacology 20050509

• Phosphodiesterase-III-inhibition with amrinone leads to contracture development in skeletal muscle preparations of malignant hyperthermia susceptible swine.

  European journal of anaesthesiology 20050401

• SCH00013, a novel Ca(2+) sensitizer with positive inotropic and no chronotropic action in heart failure.

  Journal of pharmacological sciences 20050101

• Bench-to-bedside review: Inotropic drug therapy after adult cardiac surgery -- a systematic literature review.

  Critical care (London, England) 20050101

• Meta-analysis of hemodynamic optimization: relationship to methodological quality.

  Critical care (London, England) 20050101

• Short-term fasting and lipolytic activity in rat adipocytes.

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20041001

• Successful allogeneic bone marrow transplantation for acute myelogenous leukemia after drug-induced cardiomyopathy.

  The Tohoku journal of experimental medicine 20040901

• Effects of dopamine, dobutamine, amrinone and milrinone on regional blood flow in isoflurane anesthetized dogs.

  The Journal of veterinary medical science 20040901

• Diminished inotropic response to amrinone in ventricular myocytes from myopathic hamsters is linked to depression of high-gain Ca2+-induced Ca2+ release.

  The Journal of pharmacology and experimental therapeutics 20040801

• Cardiac and vascular effects of diltiazem, dobutamine and amrinone, drugs used after myocardial revascularization.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040601

• Pharmacokinetics and pharmacodynamics of intravenous inotropic agents.

  Clinical pharmacokinetics 20040101

• Development of an in vitro model for vascular injury with human endothelial cells.

  ALTEX 20040101

• Treatment of mechanically-induced vasospasm of the carotid artery in a primate using intra-arterial verapamil: a technical case report.

  BMC cardiovascular disorders 20040101

• Identification and prediction of promiscuous aggregating inhibitors among known drugs.

  Journal of medicinal chemistry 20031009

• Effects of phosphodiesterase 3,4,5 inhibitors on hepatocyte cAMP levels, glycogenolysis, gluconeogenesis and susceptibility to a mitochondrial toxin.

  Molecular and cellular biochemistry 20031001

• Effects of preemptive therapy with milrinone or amrinone on perioperative platelet function and haemostasis in patients undergoing coronary bypass grafting.

  Platelets 20030801

• Interleukin-6 family of cytokines mediates isoproterenol-induced delayed STAT3 activation in mouse heart.

  The Journal of biological chemistry 20030606

• [Effect of dexamethasone, aminoguanidin, amrinone on oxygen utilization in endotoxin shock rabbits].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20030401

• Inhibition and facilitation by pimobendan, a calcium sensitizer, of catecholamine secretion from bovine adrenal chromaffin cells.

  Journal of pharmacological sciences 20030301

• The effect of chronic renal failure on phosphodiesterase inhibitor-induced relaxation responses in rabbit cavernosal strips.

  European journal of pharmacology 20030221

• Effects of epinephrine and phosphodiesterase III inhibitors on bupivacaine-induced myocardial depression in guinea-pig papillary muscle.

  British journal of anaesthesia 20030101

• [Levosimendan: a new option in the pharmacologic management of cardiac insufficiency].

  Gaceta medica de Mexico 20030101

• Cardiotonic bipyridine amrinone slows myosin-induced actin filament sliding at saturating [MgATP].

  Journal of muscle research and cell motility 20030101

• Possible contribution of acetylamrinone and its enhancing effects on platelet aggregation under shear stress conditions in the onset of thrombocytopenia in patients treated with amrinone.

  Thrombosis research 20030101

• Congenital junctional ectopic tachycardia: presentation and outcome.

  Indian pacing and electrophysiology journal 20030101

• Effects of cAMP modulators on long-chain fatty-acid uptake and utilization by electrically stimulated rat cardiac myocytes.

  The Biochemical journal 20021101

• Phosphodiesterase 4 inhibitor cilomilast inhibits fibroblast-mediated collagen gel degradation induced by tumor necrosis factor-alpha and neutrophil elastase.

  American journal of respiratory cell and molecular biology 20021001

• Effect of mild hypothermia on inodilator-induced vasodilation of pial arterioles in cats.

  The Journal of trauma 20021001

• Differential effects of amrinone and milrinone upon myocardial inflammatory signaling.

  Circulation 20020924

• Intraoperative insulin therapy does not reduce the need for inotropic or antiarrhythmic therapy after cardiopulmonary bypass.

  Journal of cardiothoracic and vascular anesthesia 20020801

• The effectiveness and relative effectiveness of intravenous inotropic drugs acting through the adrenergic pathway in patients with heart failure-a meta-regression analysis.

  European journal of heart failure 20020801

• Mechanisms of leptin secretion from white adipocytes.

  American journal of physiology. Cell physiology 20020701

• Effects of amrinone on hepatic ischemia-reperfusion injury in rats.

  Journal of hepatology 20020701

• Effects of amrinone on bilateral renal ischemia/reperfusion injury.

  Urological research 20020701

• High-dose amrinone is required to accelerate rewarming from deliberate mild intraoperative hypothermia for neurosurgical procedures.

  Anesthesiology 20020701

• Cardiovascular effects of a phosphodiesterase III inhibitor, amrinone, in infants: non-invasive echocardiographic evaluation.

  Pediatrics international : official journal of the Japan Pediatric Society 20020601

• PDE4 inhibitors attenuate fibroblast chemotaxis and contraction of native collagen gels.

  American journal of respiratory cell and molecular biology 20020601

• [Effects of amrinone in patients undergoing off-pump coronary artery bypass grafting].

  Masui. The Japanese journal of anesthesiology 20020501

• Role of cyclic nucleotides in ischemia and reperfusion injury of canine livers.

  Transplantation 20020415

• [Randomized controlled trial for the effect of amrinone and aprotinin on expression leukocyte adhesion molecule in patients with prosthetic valve replacement during perioperative period].

  Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao 20020401

• Cyclooxygenase-2 and adenylate cyclase/protein kinase A signaling pathway enhances angiogenesis through induction of vascular endothelial growth factor in rat sponge implants.

  Human cell 20020301

• Immunopharmacological potential of selective phosphodiesterase inhibition. II. Evidence for the involvement of an inhibitory-kappaB/nuclear factor-kappaB-sensitive pathway in alveolar epithelial cells.

  The Journal of pharmacology and experimental therapeutics 20020201

• The efficacy of preemptive Milrinone or Amrinone therapy in patients undergoing coronary artery bypass grafting.

  Anesthesia and analgesia 20020101

• Modulation of TNF and GM-CSF release from dispersed human nasal polyp cells and human whole blood by inhibitors of different PDE isoenzymes and glucocorticoids.

  Pulmonary pharmacology & therapeutics 20020101

• [Pharmacology of inotropic agents].

  Archivos de cardiologia de Mexico 20020101

• Comparison of enoximone, amrinone, or levosimendan enriched St. Thomas' hospital cardioplegic solutions used for myocardial preservation in isolated guinea pig hearts.

  Acta medica (Hradec Kralove) 20020101

• Clinical use of amrinone (a selective phosphodiesterase III inhibitor) in reconstructive surgery.

  Plastic and reconstructive surgery 20011201

• Poisoning with calcium channel blockers--a case report and review of the literature.

  Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20011201

• Adenylate cyclase/protein kinase A signaling pathway enhances angiogenesis through induction of vascular endothelial growth factor in vivo.

  Japanese journal of pharmacology 20011101

• In contrast to forskolin and 3-isobutyl-1-methylxanthine, amrinone stimulates the cardiac voltage-sensitive release mechanism without increasing calcium-induced calcium release.

  The Journal of pharmacology and experimental therapeutics 20010901

• Possible involvement of cyclic adenosine monophosphate-independent mechanism in the positive chronotropic effect of norepinephrine in the isolated guinea pig right atrium.

  Anesthesiology 20010801

• Lack of role for nitric oxide in cholinergic modulation of myocardial contractility in vivo.

  American journal of physiology. Heart and circulatory physiology 20010701

• [Randomized controlled trial for the effect of amrinone and aprotinin on proinflammatory cytokine release in patients with prosthetic valve replacement during perioperative period].

  Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao 20010601

• Cloning of dog heart PDE1A - a first detailed characterization at the molecular level in this species.

  Gene 20010502

• Amrinone can accelerate the cooling rate of core temperature during deliberate mild hypothermia for neurosurgical procedures.

  British journal of anaesthesia 20010501

• Effects of the specific phosphodiesterase inhibitors on alloxan-induced diabetic rabbit cavernous tissue in vitro.

  International journal of impotence research 20010201

• Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity.

  Biochemical pharmacology 20000215

• Reversal of propranolol blockade of adrenergic receptors and related toxicity with drugs that increase cyclic AMP.

  Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 19990901

• Amrinone, a phosphodiesterase III inhibitor, and arachidonic acid metabolism in humans.

  Journal of cardiovascular pharmacology 19990101

• Dose-related cardiovascular effects of amrinone and epinephrine in reversing bupivacaine-induced cardiovascular depression.

  Acta anaesthesiologica Scandinavica 19980701

• A multicenter, randomized, blind comparison of amrinone with milrinone after elective cardiac surgery.

  Anesthesia and analgesia 19980401

• Differential modulation of cytokine production by drugs: implications for therapy in heart failure.

  Journal of molecular and cellular cardiology 19961201

• [Hemodynamic effects of amrinone, phosphodiesterase inhibitor, early after coronary artery bypass grafting].

  [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai 19961101

• Amrinone is superior to epinephrine in reversing bupivacaine-induced cardiovascular depression in sevoflurane-anesthetized dogs.

  Anesthesiology 19950701

• Resuscitation from bupivacaine-induced asystole in rats: comparison of different cardioactive drugs.

  Anesthesia and analgesia 19950601

• Electrophysiologic and proarrhythmic effects of intravenous inotropic agents.

  Progress in cardiovascular diseases 19950101

• [Effects of amrinone on left ventricular function following open heart surgery--analysis with left ventricular pressure volume loops].

  [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai 19941001

• A comparison of combined amrinone and glucagon therapy to glucagon alone for cardiovascular depression associated with propranolol toxicity in a canine model.

  The American journal of emergency medicine 19930701

• Modulation of inotropic therapy by venodilation in acute heart failure: a randomised comparison of four inotropic agents, alone and combined with isosorbide dinitrate.

  Journal of cardiovascular pharmacology 19920101

• A comparison of amrinone and glucagon therapy for cardiovascular depression associated with propranolol toxicity in a canine model.

  Journal of toxicology. Clinical toxicology 19920101

• Amrinone for refractory cardiogenic shock following chloroquine poisoning.

  Intensive care medicine 19910101

• Pancytopenia secondary to short-term, high-dose intravenous infusion of amrinone.

  DICP : the annals of pharmacotherapy 19901201

• Effect of amrinone on anthracycline-induced lethal and cardiac toxicity in mice and rats.

  Medical oncology and tumor pharmacotherapy 19900101

• Effects of amrinone on the right side of the heart.

  Journal of cardiothoracic anesthesia 19891201

• Cardiotonic agents. 9. Synthesis and biological evaluation of a series of (E)-4,5-dihydro-6-[2-[4-(1H-imidazol-1-yl)phenyl]ethenyl]-3 (2H)-pyridazinones: a novel class of compounds with positive inotropic, antithrombotic, and vasodilatory activities for the treatment of congestive heart failure.

  Journal of medicinal chemistry 19890201

• Combined therapy with dobutamine and amrinone in severe heart failure. Improved hemodynamics and increased activation of the renin-angiotensin system with combined intravenous therapy.

  Chest 19871001

• The influence of amrinone on cardiac toxicity induced by adriamycin in rats.

  Archives internationales de pharmacodynamie et de therapie 19861001

• The haemodynamic effects of amrinone in patients with mitral stenosis and pulmonary hypertension.

  European heart journal 19860901

• The beneficial effect of amrinone on acute drug-induced heart failure in the anaesthetised dog.

  Cardiovascular research 19850801

• The new inotropic phosphodiesterase inhibitors.

  Archives internationales de physiologie et de biochimie 19841101

• [Right ventricular hemodynamics and lung function following amrinone injection].

  Zeitschrift fur Kardiologie 19841001

• In vitro and in vivo studies of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), a novel positive inotropic drug, in various animals.

  Arzneimittel-Forschung 19840101

• Comparative actions of hydralazine, nifedipine and amrinone in primary pulmonary hypertension.

  The American journal of cardiology 19831101