616-45-5 | 2-Pyrrolidone

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$13.00	$9.00
5g	98%	in stock	$15.00	$10.00
25g	98%	in stock	$18.00	$12.00
100g	98%	in stock	$30.00	$21.00
500g	>98.0%(GC)	in stock	$40.00	$28.00
2.5kg	≥ 99% (GC)	in stock	$164.00	$115.00
5kg	≥ 99% (GC)	in stock	$252.00	$176.00
10kg	≥ 99% (GC)	in stock	$434.00	$304.00
25kg	≥ 99% (GC)	in stock	$932.00	$652.00

Description

• Catalog Number: AB44225
• Chemical Name: 2-Pyrrolidone
• CAS Number: 616-45-5
• Molecular Formula: C4H7NO
• Molecular Weight: 85.1045
• MDL Number: MFCD19217896
• SMILES: O=C1CCCN1

Computed Properties

• Complexity: 69.9
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• XLogP3: -0.8

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  Current drug discovery technologies 20100601

• (3aR*,6S*,7S*,7aR*)-2-(4-Methoxy-benz-yl)-7-(4-nitro-phen-yl)-6-phenyl-3a,6,7,7a-tetra-hydro-isoindolin-1-one.

  Acta crystallographica. Section E, Structure reports online 20100601

• Influence of polymer content on stabilizing milled amorphous salbutamol sulphate.

  International journal of pharmaceutics 20100531

• Influence of excipients in comilling on mitigating milling-induced amorphization or structural disorder of crystalline pharmaceutical actives.

  Journal of pharmaceutical sciences 20100501

• μ-η:η-Peroxido-bis-[nitratodioxido-bis(pyrrolidin-2-one)uranium(VI)].

  Acta crystallographica. Section E, Structure reports online 20100501

• Synthesis of spirocyclic carbazole- and acridine-lactams.

  Organic & biomolecular chemistry 20100421

• Total oxidation of toluene on Pt/CeO2-ZrO2-Bi2O3/gamma-Al2O3 catalysts prepared in the presence of polyvinyl pyrrolidone.

  Journal of hazardous materials 20100415

• Platinum-catalyzed intramolecular hydrohydrazination: evidence for alkene insertion into a Pt-N bond.

  Journal of the American Chemical Society 20100414

• Pharmacodynamics of a losartan transdermal system for the treatment of hypertension.

  Drug development and industrial pharmacy 20100401

• Reducing ability and mechanism for polyvinylpyrrolidone (PVP) in silver nanoparticles synthesis.

  Journal of nanoscience and nanotechnology 20100401

• Ethyl 1-benzyl-4-hydr-oxy-2-methyl-5-oxopyrrolidine-3-carboxyl-ate.

  Acta crystallographica. Section E, Structure reports online 20100401

• Interactions at the bilayer interface and receptor site induced by the novel synthetic pyrrolidinone analog MMK3.

  Biochimica et biophysica acta 20100301

• Design, characterization, and evaluation of meloxicam gel prepared by suspension and solution polymerization using solubility parameter as the basis for development.

  AAPS PharmSciTech 20100301

• Effects of thermal curing conditions on drug release from polyvinyl acetate-polyvinyl pyrrolidone matrices.

  AAPS PharmSciTech 20100301

• Buccal drug delivery of pravastatin sodium.

  AAPS PharmSciTech 20100301

• Polymer blends used to prepare nifedipine loaded hollow microspheres for a floating-type oral drug delivery system: in vitro evaluation.

  Archives of pharmacal research 20100301

• Molecular genetic tools to infer the origin of forest plants and wood.

  Applied microbiology and biotechnology 20100201

• BIN1 localizes the L-type calcium channel to cardiac T-tubules.

  PLoS biology 20100201

• Polymer-drug interactions and wetting of solid dispersions.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100131

• Influence of temperature on the solubilization of thiabendazole by combined action of solid dispersions and co-solvents.

  International journal of pharmaceutics 20100115

• Brivaracetam (ucb 34714) inhibits Na(+) current in rat cortical neurons in culture.

  Epilepsy research 20100101

• Single-walled carbon nanotubes dispersed in aqueous media via non-covalent functionalization: effect of dispersant on the stability, cytotoxicity, and epigenetic toxicity of nanotube suspensions.

  Water research 20100101

• Role of platelets in neuroinflammation: a wide-angle perspective.

  Journal of neuroinflammation 20100101

• Chemistry of secondary polyphenols produced during processing of tea and selected foods.

  International journal of molecular sciences 20100101

• SSHscreen and SSHdb, generic software for microarray based gene discovery: application to the stress response in cowpea.

  Plant methods 20100101

• Synthesis and pharmacological evaluation of pyrrolidin-2-one derivatives as antiarrhythmic, antihypertensive and alpha-adrenolytic agents.

  Pharmacological reports : PR 20100101

• [Post-operative bacteremia caused by multidrug-resistant Aerococcus viridans in a patient with gall bladder cancer].

  Mikrobiyoloji bulteni 20100101

• Generating a generation of proteasome inhibitors: from microbial fermentation to total synthesis of salinosporamide a (marizomib) and other salinosporamides.

  Marine drugs 20100101

• A review on progress in QSPR studies for surfactants.

  International journal of molecular sciences 20100101

• A preliminary study of reactive oxygen species activity within motile Boer buck sperm using confocal laser scanning microscope (CLSM).

  La Clinica terapeutica 20100101

• Tetramic and tetronic acids as scaffolds in bioinorganic and bioorganic chemistry.

  Bioinorganic chemistry and applications 20100101

• Prevalence of Plasmodium vivax VK210 and VK247 subtype in Myanmar.

  Malaria journal 20100101

• Hall measurements on carbon nanotube paper modified with electroless deposited platinum.

  Nanoscale research letters 20100101

• Well-aligned Nickel Nanochains Synthesized by a Template-free Route.

  Nanoscale research letters 20100101

• Engineering of N. benthamiana L. plants for production of N-acetylgalactosamine-glycosylated proteins--towards development of a plant-based platform for production of protein therapeutics with mucin type O-glycosylation.

  BMC biotechnology 20100101

• Novel rare earth-polyvinyl pyridine complex functionalized hybrid silica microspheres: molecular assembly and photophysical property.

  Photochemistry and photobiology 20100101

• ETM-ANN approach application for thiobenzamide and quinolizidine derivatives.

  Journal of biomedicine & biotechnology 20100101

• Antiarrhythmic activity of novel S-enantiomers of pyrrolidin-2-one derivatives with adrenolytic properties.

  Acta poloniae pharmaceutica 20100101

• Fast Dissolving Sublingual Films of Ondansetron Hydrochloride: Effect of Additives on in vitro Drug Release and Mucosal Permeation.

  Journal of young pharmacists : JYP 20100101

• [Further improvement of the methods for the arrest of nasal bleeding].

  Vestnik otorinolaringologii 20100101

• Green synthesis of silver/montmorillonite/chitosan bionanocomposites using the UV irradiation method and evaluation of antibacterial activity.

  International journal of nanomedicine 20100101

• Engineering the chloroplast targeted malarial vaccine antigens in Chlamydomonas starch granules.

  PloS one 20100101

• Transdermal drug delivery of labetalol hydrochloride: Feasibility and effect of penetration enhancers.

  Journal of pharmacy & bioallied sciences 20100101

• Development of a floating dosage form of ranitidine hydrochloride by statistical optimization technique.

  Journal of young pharmacists : JYP 20100101

• Methyl 7,8-diacet-oxy-11-oxo-5-(2-oxo-pyrrolidin-1-yl)-7,9-epoxy-cyclo-penta-[4,5]pyrido[1,2-a]quinoline-10-carboxyl-ate sesquihydrate.

  Acta crystallographica. Section E, Structure reports online 20100101

• In vitro response of retinal pigment epithelial cells exposed to chitosan materials prepared with different cross-linkers.

  International journal of molecular sciences 20100101

• Infective Endocarditis: Identification of Catalase-Negative, Gram-Positive Cocci from Blood Cultures by Partial 16S rRNA Gene Analysis and by Vitek 2 Examination.

  The open microbiology journal 20100101

• Preparation of Aligned Ultra-long and Diameter-controlled Silicon Oxide Nanotubes by Plasma Enhanced Chemical Vapor Deposition Using Electrospun PVP Nanofiber Template.

  Nanoscale research letters 20100101

• Formulation and evaluation of trimetazidine dihydrochloride extended release tablets by melt congealing method.

  Indian journal of pharmaceutical sciences 20100101

• Effect of Different Carriers on in vitro Permeation of Meloxicam through Rat Skin.

  Indian journal of pharmaceutical sciences 20100101

• Iron oxide-based nanomagnets in nanomedicine: fabrication and applications.

  Nano reviews 20100101

• The effect of pectin on swelling and permeability characteristics of free films containing Eudragit RL and/or RS as a coating formulation aimed for colonic drug delivery.

  Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101

• Preparation and in-vitro evaluation of indomethacin nanoparticles.

  Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101

• Cobalt-catalyzed regioselective synthesis of pyrrolidinone derivatives by reductive coupling of nitriles and acrylamides.

  Journal of the American Chemical Society 20091230

• Selective light emission in nonbonding electron transitions in poly(vinyl pyrrolidone) molecules on spin-coating in thin layers.

  The journal of physical chemistry. A 20091224

• Design of a 24-hour controlled porosity osmotic pump system containing PVP: formulation variables.

  Drug development and industrial pharmacy 20091201

• trans-Bis(1-cyclo-hexyl-pyrrolidin-2-one)dinitratopalladium(II).

  Acta crystallographica. Section E, Structure reports online 20091201

• Current and Novel Inhibitors of HIV Protease.

  Viruses 20091201

• Zinc supplementation improves the outcome of chronic hepatitis C and liver cirrhosis.

  Journal of clinical biochemistry and nutrition 20091101

• 6-Benzyl-3-(1,4-dioxaspiro-[4.5]decan-2-yl)-8,8-dimethyl-1-oxa-2,6-diaza-spiro-[4.4]non-2-ene-7,9-dione.

  Acta crystallographica. Section E, Structure reports online 20091101

• Nitro-Mannich/lactamization cascades for the direct stereoselective synthesis of pyrrolidin-2-ones.

  Organic letters 20091015

• Translational and rotational diffusion of a small globular protein under crowded conditions.

  The journal of physical chemistry. B 20091008

• Design, synthesis and pharmacological evaluation of new 1-[3-(4-arylpiperazin-1-yl)-2-hydroxy-propyl]-3,3-diphenylpyrrolidin-2-one derivatives with antiarrhythmic, antihypertensive, and alpha-adrenolytic activity.

  European journal of medicinal chemistry 20091001

• Rubisco in planta kcat is regulated in balance with photosynthetic electron transport.

  Journal of experimental botany 20091001

• Thermally induced dissociation nature of pure 2-pyrrolidinone via near-infrared correlation spectroscopy analysis.

  Applied spectroscopy 20091001

• Application of simplex lattice design and desirability function for the formulation development of mouth dissolving film of salbutamol sulphate.

  Current drug delivery 20091001

• 1,3,5-Tris(N-phenyl-benzimidazol-2-yl)benzene methanol solvate.

  Acta crystallographica. Section E, Structure reports online 20091001

• Development and optimization of a sublingual tablet formulation for physostigmine salicylate.

  Acta pharmaceutica (Zagreb, Croatia) 20090901

• [Regioselectivity in the dehydrogenation of substituted ethylenediamines as nicotine models].

  Die Pharmazie 20090901

• Metadoxine, an ion-pair of pyridoxine and L-2-pyrrolidone-5-carboxylate, blocks adipocyte differentiation in association with inhibition of the PKA-CREB pathway.

  Archives of biochemistry and biophysics 20090815

• Grafting modification and structural degradation of multi-walled carbon nanotubes under the effect of ultrasonics sonochemistry.

  Ultrasonics sonochemistry 20090801

• (3aR,8aS,9S,9aR)-9-Hydroxy-perhydro-furo[3,2-f]indolizin-6-one.

  Acta crystallographica. Section E, Structure reports online 20090801

• A one-pot method to enhance dissolution rate of low solubility drug molecules using dispersion polymerization in supercritical carbon dioxide.

  International journal of pharmaceutics 20090730

• Double-layer weekly sustained release transdermal patch containing gestodene and ethinylestradiol.

  International journal of pharmaceutics 20090730

• Microwave assisted synthesis of unsaturated jasmone heterocyclic analogues as new fragrant substances.

  European journal of medicinal chemistry 20090701

• Profile of the new pyrrolidone derivative seletracetam (ucb 44212) in animal models of epilepsy.

  European journal of pharmacology 20090701

• SAM levels, gene expression of SAM synthetase, methionine synthase and ACC oxidase, and ethylene emission from N. suaveolens flowers.

  Plant molecular biology 20090701

• Chemical penetration enhancers: a patent review.

  Expert opinion on therapeutic patents 20090701

• Optical properties in nanofluids of gold nanoparticles in poly(vinylpyrrolidone).

  Journal of nanoscience and nanotechnology 20090701

• Phase behavior of mixtures of positively charged colloidal platelets and nonadsorbing polymer.

  Langmuir : the ACS journal of surfaces and colloids 20090602

• Improvement of cytocompatibility of electrospinning PLLA microfibers by blending PVP.

  Journal of materials science. Materials in medicine 20090601

• A novel hydrophilic adhesive matrix with self-enhancement for drug percutaneous permeation through rat skin.

  Pharmaceutical research 20090601

• Cefuroxime axetil solid dispersion with polyglycolized glycerides for improved stability and bioavailability.

  The Journal of pharmacy and pharmacology 20090601

• [Study on chemical constituents from roots of Saussurea lappa].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090501

• Vitamin B12 diffusion and binding in crosslinked poly(acrylic acid)s and poly(acrylic acid-co-N-vinyl pyrrolidinone)s.

  International journal of pharmaceutics 20090417

• Preparation and in vitro evaluation of a new fentanyl patch based on acrylic/silicone pressure-sensitive adhesive blends.

  Drug development and industrial pharmacy 20090401

• (8aS)-7,8,8a,9-Tetra-hydro-thieno[3,2-f]indolizin-6(4H)-one.

  Acta crystallographica. Section E, Structure reports online 20090401

• Plasticizers in the manufacture of novel skin-bioadhesive patches.

  International journal of pharmaceutics 20090331

• Anti-inflammatory activity and PGE2 inhibitory properties of novel phenylcarbamoylmethyl ester-containing compounds.

  Molecules (Basel, Switzerland) 20090211

• Pesticidal seed coats based on azadirachtin-A: release kinetics, storage life and performance.

  Pest management science 20090201

• Formulation and evaluation of in situ gelling thermoreversible mucoadhesive gel of fluconazole.

  Drug discoveries & therapeutics 20090201

• Mechanistic studies on the copper-catalyzed N-arylation of amides.

  Journal of the American Chemical Society 20090114

• Effect of PVP K30 and/or L-arginine on stability constant of etoricoxib-HPbetaCD inclusion complex: preparation and characterization of etoricoxib-HPbetaCD binary system.

  Drug development and industrial pharmacy 20090101

• Quantification of fibronectin 1 (FN1) splice variants, including two novel ones, and analysis of integrins as candidate FN1 receptors in bovine preimplantation embryos.

  BMC developmental biology 20090101

• Simple high-cell density fed-batch technique for high-level recombinant protein production with Pichia pastoris: Application to intracellular production of Hepatitis B surface antigen.

  Microbial cell factories 20090101

• Approaches to polymer selection for mascara formulation.

  Journal of cosmetic science 20090101

• Vancomycin resistant enterococci (VRE) in Swedish sewage sludge.

  Acta veterinaria Scandinavica 20090101

• Gold nanoparticles induce cytotoxicity in the alveolar type-II cell lines A549 and NCIH441.

  Particle and fibre toxicology 20090101

• Review of levetiracetam, with a focus on the extended release formulation, as adjuvant therapy in controlling partial-onset seizures.

  Neuropsychiatric disease and treatment 20090101

• Genome-wide analysis reveals rapid and dynamic changes in miRNA and siRNA sequence and expression during ovule and fiber development in allotetraploid cotton (Gossypium hirsutum L.).

  Genome biology 20090101

• Phenylalanine-rich peptides potently bind ESAT6, a virulence determinant of Mycobacterium tuberculosis, and concurrently affect the pathogen's growth.

  PloS one 20090101

• Alfuzosin hydrochloride transdermal films: evaluation of physicochemical, in vitro human cadaver skin permeation and thermodynamic parameters.

  International braz j urol : official journal of the Brazilian Society of Urology 20090101

• Carvedilol-loaded mucoadhesive buccal tablets: influence of various mucoadhesive polymers on drug release behavior.

  PDA journal of pharmaceutical science and technology 20090101

• Development and evaluation of nefopam transdermal matrix patch system in human volunteers.

  PDA journal of pharmaceutical science and technology 20090101

• In vitro production of buffalo embryos from stepwise vitrified immature oocytes.

  Veterinaria italiana 20090101

• In situ forming polymeric drug delivery systems.

  Indian journal of pharmaceutical sciences 20090101

• Enhanced Luminescence of Eu-Doped TiO2Nanodots.

  Nanoscale research letters 20090101

• Gram-negative bacterial sensors for eukaryotic signal molecules.

  Sensors (Basel, Switzerland) 20090101

• Brivaracetam and seletracetam, two new SV2A ligands, improve paroxysmal dystonia in the dt sz mutant hamster.

  European journal of pharmacology 20081228

• Protein conformation in amorphous solids by FTIR and by hydrogen/deuterium exchange with mass spectrometry.

  Biophysical journal 20081215

• Analysis of several methods for the extraction of high quality DNA from acetic acid bacteria in wine and vinegar for characterization by PCR-based methods.

  International journal of food microbiology 20081210

• Characterization of ternary complexes of meloxicam-HPbetaCD and PVP or L-arginine prepared by the spray-drying technique.

  Acta pharmaceutica (Zagreb, Croatia) 20081201

• Treatment of Lennox-Gastaut syndrome: overview and recent findings.

  Neuropsychiatric disease and treatment 20081201

• Preparation and characterization of electrospun silica nanofibers from PVP/P123 blended polymer solution.

  Journal of nanoscience and nanotechnology 20081001

• HPLC analysis, isolation and identification of a new degradation product in carvedilol tablets.

  Journal of pharmaceutical and biomedical analysis 20080910

• Biphasic hydrogenation over PVP stabilized Rh nanoparticles in hydroxyl functionalized ionic liquids.

  Inorganic chemistry 20080901

• Localization of sucrose synthase in developing seed and siliques of Arabidopsis thaliana reveals diverse roles for SUS during development.

  Journal of experimental botany 20080901

• Electron capture dissociation, electron detachment dissociation, and collision-induced dissociation of polyamidoamine (PAMAM) dendrimer ions with amino, amidoethanol, and sodium carboxylate surface groups.

  Journal of the American Society for Mass Spectrometry 20080901

• Mucoadhesive bilayered patches for administration of sumatriptan succinate.

  AAPS PharmSciTech 20080901

• Development and in-vitro evaluation of transdermal matrix films of metoprolol tartrate.

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080901

• Thioesterase-like role for fungal PKS-NRPS hybrid reductive domains.

  Journal of the American Chemical Society 20080820

• Surfactant-mediated growth of nanostructured zinc oxide thin films via electrodeposition and their photoelectrochemical performance.

  Nanotechnology 20080813

• A concise and straightforward total synthesis of (+/-)-salinosporamide A, based on a biosynthesis model.

  Organic & biomolecular chemistry 20080807

• The interaction of gabapentin and N6-(2-phenylisopropyl)-adenosine R-(-)isomer (R-PIA) on mechanical allodynia in rats with a spinal nerve ligation.

  Journal of Korean medical science 20080801

• Structure formation and characterization of injectable drug loaded biodegradable devices: in situ implants versus in situ microparticles.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080703

• Protein engineering strategies for sustained glucagon-like peptide-1 receptor-dependent control of glucose homeostasis.

  Diabetes 20080701

• Process and formulation characterizations of the thermal adhesion granulation (TAG) process for improving granular properties.

  International journal of pharmaceutics 20080605

• Sumatriptan succinate transdermal delivery systems for the treatment of migraine.

  Journal of pharmaceutical sciences 20080601

• A study on maize proteins as a potential new tablet excipient.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080601

• Synthesis and characterization of pectin/PVP hydrogel membranes for drug delivery system.

  AAPS PharmSciTech 20080601

• Ceftobiprole: an extended-spectrum anti-methicillin-resistant Staphylococcus aureus cephalosporin.

  The Annals of pharmacotherapy 20080601

• (11R,11aS)-11-Hydr-oxy-1,5,11,11a-tetra-hydro-1-benzothieno[2,3-f]indolizin-3(2H)-one.

  Acta crystallographica. Section E, Structure reports online 20080601

• Benzyl 2-cyano-3,3-dimethyl-1-pyrrolidinecarboxylate, a versatile intermediate for the synthesis of 3,3-dimethylproline derivatives.

  The Journal of organic chemistry 20080516

• Arsenic adsorption by polyvinyl pyrrolidone K25 coated cassava peel carbon from aqueous solution.

  Journal of hazardous materials 20080501

• Evaluation of the enthalpy of formation, proton affinity, and gas-phase basicity of gamma-butyrolactone and 2-pyrrolidinone by isodesmic reactions.

  The journal of physical chemistry. A 20080501

• Stereochemistry of flavonoidal alkaloids from Dracocephalum rupestre.

  Phytochemistry 20080401

• Application of mass spectrometry for the detection of glycation and oxidation products in milk proteins.

  Annals of the New York Academy of Sciences 20080401

• tert-Butyl 5-(4-methoxy-phen-yl)-1-methyl-2-oxopyrrolidin-3-yl carbonate.

  Acta crystallographica. Section E, Structure reports online 20080401

• Generation of superoxide anion in chloroplasts of Arabidopsis thaliana during active photosynthesis: a focus on rapidly induced genes.

  Plant molecular biology 20080301

• In vitro activity profile of ceftobiprole, an anti-MRSA cephalosporin, against recent gram-positive and gram-negative isolates of European origin.

  The Journal of antimicrobial chemotherapy 20080301

• Effect of internal lubricating agents of disposable soft contact lenses on higher-order aberrations after blinking.

  Eye & contact lens 20080301

• Percutaneous permeation enhancement by terpenes: mechanistic view.

  The AAPS journal 20080301

• Preparation and characterization of electrospun SiO2 nanofibers.

  Journal of nanoscience and nanotechnology 20080301

• Nano-vectors for efficient liver specific gene transfer.

  International journal of nanomedicine 20080301

• 4-Hydr-oxy-5-(4-methoxy-phen-yl)pyrrolidin-2-one.

  Acta crystallographica. Section E, Structure reports online 20080301

• Zero-order delivery of a highly soluble, low dose drug alfuzosin hydrochloride via gastro-retentive system.

  International journal of pharmaceutics 20080204

• Solubility-modulated monolithic osmotic pump tablet for atenolol delivery.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080201

• 3-Aminopyrrolidines from alpha-aminoacids: total synthesis of (+)-nemonapride from D-alanine.

  The Journal of organic chemistry 20080201

• Role of additives like polymers and surfactants in the crystallization of mebendazole.

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080201

• Monotherapy for partial epilepsy: focus on levetiracetam.

  Neuropsychiatric disease and treatment 20080201

• 1-Benzyl-6-phenyl-imino-5-(pyrrol-2-yl-idene)hexa-hydro-pyrimidine-2,4-dione.

  Acta crystallographica. Section E, Structure reports online 20080201

• Cardiovascular effects of transdermally delivered bupranolol in rabbits: effect of chemical penetration enhancers.

  Life sciences 20080130

• Synthesis and evaluation of a gamma-lactam as a highly selective EP2 and EP4 receptor agonist.

  Bioorganic & medicinal chemistry letters 20080115

• Development of monoclonal antibodies for the fusarin mycotoxins.

  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20080101

• Regulation of DNA synthesis and the cell cycle in human prostate cancer cells and lymphocytes by ovine uterine serpin.

  BMC cell biology 20080101

• Identification and characterization of a novel Plasmodium falciparum merozoite apical protein involved in erythrocyte binding and invasion.

  PloS one 20080101

• Antibacterial and antimycotic activity of a cross-linked electrospun poly(vinyl pyrrolidone)-iodine complex and a poly(ethylene oxide)/poly(vinyl pyrrolidone)-iodine complex.

  Journal of biomaterials science. Polymer edition 20080101

• Sperm-derived histones contribute to zygotic chromatin in humans.

  BMC developmental biology 20080101

• Management of contaminated autologous grafts in plastic surgery.

  Eplasty 20080101

• The Arabidopsis thaliana response regulator ARR22 is a putative AHP phospho-histidine phosphatase expressed in the chalaza of developing seeds.

  BMC plant biology 20080101

• One-pot parallel solution-phase synthesis of 1-substituted 4-(2-aminoethyl)-1H-pyrazol-5-ols.

  Journal of combinatorial chemistry 20080101

• Ruthenium-catalyzed carbonylative cycloaddition reactions involving carbonyl and imino groups as assembling units.

  Chemical record (New York, N.Y.) 20080101

• Rapid and high quality DNA isolation from Origanum onites for RAPD and ISSR analysis.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101

• Proteomic analysis of protein deposits on worn daily wear silicone hydrogel contact lenses.

  Molecular vision 20080101

• Abstracts of papers presented at the 2008 pittsburgh conference.

  Journal of automated methods & management in chemistry 20080101

• Modifications of antiepileptic drugs for improved tolerability and efficacy.

  Perspectives in medicinal chemistry 20080101

• Design and development of mixed film of pectin: ethyl cellulose for colon specific drug delivery of sennosides and triphala.

  Indian journal of pharmaceutical sciences 20080101

• Optimization of fast dissolving etoricoxib tablets prepared by sublimation technique.

  Indian journal of pharmaceutical sciences 20080101

• Flow of Formulation Granules through a Conical Hopper.

  Indian journal of pharmaceutical sciences 20080101

• Treatment of myoclonic seizures in patients with juvenile myoclonic epilepsy.

  Neuropsychiatric disease and treatment 20071201

• Mixed transition metal-lanthanide complexes at high oxidation states: heteronuclear CeIVMnIV clusters.

  Inorganic chemistry 20071112

• Complementary stereocontrolled approaches to 2-pyrrolidinones bearing a vicinal amino diol subunit with three continuous chiral centers: a formal asymmetric synthesis of (-)-detoxinine.

  The Journal of organic chemistry 20071109

• Pyrrolidinone-modified di- and tripeptides: highly diastereoselective preparation and investigation of their stability.

  Organic & biomolecular chemistry 20071107

• Biosynthesis of violacein: a genuine intermediate, protoviolaceinic acid, produced by VioABDE, and insight into VioC function.

  Chemical communications (Cambridge, England) 20071028

• A practical synthesis of (3R,4R)-N-tert-butoxycarbonyl-4-hydroxymethylpyrrolidin-3-ol.

  Organic & biomolecular chemistry 20070907

• Solubilization of poorly soluble compounds using 2-pyrrolidone.

  International journal of pharmaceutics 20070905

• Quantitative phosphoproteomic analysis of plasma membrane proteins reveals regulatory mechanisms of plant innate immune responses.

  The Plant journal : for cell and molecular biology 20070901

• Synthesis and pharmacological evaluation of new 1-[3-(4-arylpiperazin-1-yl)-2-hydroxypropyl]-pyrrolidin-2-one derivatives with anti-arrhythmic, hypotensive, and alpha-adrenolytic activity.

  Archiv der Pharmazie 20070901

• An open trial of levetiracetam for segmental and generalized dystonia.

  Movement disorders : official journal of the Movement Disorder Society 20070815

• Effect of pore former on the properties of casted film prepared from blends of Eudragit NE 30 D and Eudragit L 30 D-55.

  Chemical & pharmaceutical bulletin 20070801

• Site-specific formation of Maillard, oxidation, and condensation products from whey proteins during reaction with lactose.

  Journal of agricultural and food chemistry 20070725

• Preparation of magnetite nanocrystals with surface reactive moieties by one-pot reaction.

  Journal of colloid and interface science 20070715

• Effect of hydrophilic polymers on buccoadhesive Eudragit patches of propranolol hydrochloride using factorial design.

  AAPS PharmSciTech 20070622

• Modulation of drug release kinetics from hydroxypropyl methyl cellulose matrix tablets using polyvinyl pyrrolidone.

  International journal of pharmaceutics 20070607

• Monitoring of dissolution induced changes in film coat composition by 1H NMR spectroscopy and SEM.

  Journal of controlled release : official journal of the Controlled Release Society 20070604

• Biomass in the manufacture of industrial products--the use of proteins and amino acids.

  Applied microbiology and biotechnology 20070601

• A beta-keto ester as a novel, efficient, and versatile ligand for copper(I)-catalyzed C-N, C-O, and C-S coupling reactions.

  The Journal of organic chemistry 20070511

• Synthesis and stabilization of Prussian blue nanoparticles and application for sensors.

  Journal of colloid and interface science 20070501

• Development of photolabile caged analogs of endothelin-1.

  Peptides 20070501

• Problems of positive list system revealed by survey of pesticide residue in food.

  The Journal of toxicological sciences 20070501

• Novel synthons from mucochloric acid: the first use of alpha,beta-dichloro-gamma-butenolides and gamma-butyrolactams for direct vinylogous aldol addition.

  The Journal of organic chemistry 20070427

• Determination of N-vinyl-2-pyrrolidone and N-methyl-2-pyrrolidone in drugs using polypyrrole-based headspace solid-phase microextraction and gas chromatography-nitrogen-phosphorous detection.

  Analytica chimica acta 20070321

• Organocatalytic sequential alpha-amination-Horner-Wadsworth-Emmons olefination of aldehydes: enantioselective synthesis of gamma-amino-alpha,beta-unsaturated esters.

  Organic letters 20070315

• A novel in situ forming drug delivery system for controlled parenteral drug delivery.

  International journal of pharmaceutics 20070306

• Dip-pen lithography using pens of different thicknesses.

  Journal of nanoscience and nanotechnology 20070301

• Surface enhanced optical absorption and photoluminescence in nonbonding electrons in small poly(vinylpyrrolidone) molecules.

  The Journal of chemical physics 20070227

• Intramolecular PIFA-mediated alkyne amidation and carboxylation reaction.

  The Journal of organic chemistry 20070216

• Controlled synthesis and association behavior of graft Pluronic in aqueous solutions.

  Journal of colloid and interface science 20070215

• Diffusion and structure of water in polymers containing N-vinyl-2-pyrrolidone.

  The journal of physical chemistry. B 20070208

• Synthesis of the pyrrolidinone core of KSM-2690 B.

  Organic letters 20070201

• Preparation and in vitro evaluation of ethyl cellulose microspheres containing stavudine by the double emulsion method.

  Die Pharmazie 20070201

• Design and in vitro testing of a floatable gastroretentive tablet of metformin hydrochloride.

  Die Pharmazie 20070201

• Purification and characterization of alcohol dehydrogenase reducing N-benzyl-3-pyrrolidinone from Geotrichum capitatum.

  Journal of bioscience and bioengineering 20070201

• Dehydration versus deamination of N-terminal glutamine in collision-induced dissociation of protonated peptides.

  Journal of the American Society for Mass Spectrometry 20070101

• Seletracetam (UCB 44212).

  Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20070101

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  Current eye research 20070101

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  Journal of nanobiotechnology 20070101

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  Cryo letters 20070101

• Physiological evaluation of the filamentous fungus Trichoderma reesei in production processes by marker gene expression analysis.

  BMC biotechnology 20070101

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  BMC developmental biology 20070101

• Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions.

  BMC genomics 20070101

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  BMC cancer 20070101

• Efficacy of two ethanol-based skin antiseptics on the forehead at shorter application times.

  BMC microbiology 20070101

• A convenient allylsilane-N-acyliminium route toward indolizidine and quinolizidine alkaloids.

  Beilstein journal of organic chemistry 20070101

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  PloS one 20070101

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  Molecular pain 20070101

• Superparamagnetic iron oxide nanoparticles coated with galactose-carrying polymer for hepatocyte targeting.

  Journal of biomedicine & biotechnology 20070101

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  Chemical communications (Cambridge, England) 20061221

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  Bioorganic & medicinal chemistry letters 20061101

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  Langmuir : the ACS journal of surfaces and colloids 20060926

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  Journal of hazardous materials 20060921

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  International journal of pharmaceutics 20060914

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  AAPS PharmSciTech 20060901

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  AAPS PharmSciTech 20060901

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  Organic letters 20060831

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  The Journal of chemical physics 20060721

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  AAPS PharmSciTech 20060601

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  Toxicology letters 20060410

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  The European physical journal. E, Soft matter 20060401

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  Organic letters 20060316

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  European journal of medicinal chemistry 20060301

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  The AAPS journal 20060301

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  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060201

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  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060201

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  International journal of medical microbiology : IJMM 20060201

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  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060101

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  Eksperimental'naia i klinicheskaia farmakologiia 20060101

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  Bioorganicheskaia khimiia 20060101

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  Drugs in R&D 20060101

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  BMC genomics 20060101

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  Reproductive biology and endocrinology : RB&E 20060101

• Identification of prevalent potyvirus on maize and johnsongrass in corn fields of Tehran province of Iran and a study on some of its properties.

  Communications in agricultural and applied biological sciences 20060101

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  The Journal of organic chemistry 20051209

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  The journal of physical chemistry. A 20051208

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  Environmental health perspectives 20051201

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  Organic letters 20051124

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  Macromolecular bioscience 20051104

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  The journal of physical chemistry. B 20051020

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  Parasitology 20051001

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  International journal of pharmaceutics 20050930

• Development of two enzyme-linked immunosorbent assays for detection of endosulfan residues in agricultural products.

  Journal of agricultural and food chemistry 20050921

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  The Journal of organic chemistry 20050902

• Concentrations of N-methyl-2-pyrrolidone (NMP) and its metabolites in plasma and urine following oral administration of NMP to rats.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050901

• Ocular inserts for controlled delivery of pefloxacin mesylate: preparation and evaluation.

  Acta pharmaceutica (Zagreb, Croatia) 20050901

• Stereoselective synthesis of constrained azacyclic hydroxyethylene isosteres as aspartic protease inhibitors: dipolar cycloaddition and related methodologies toward branched pyrrolidine and pyrrolidinone carboxylic acids.

  The Journal of organic chemistry 20050819

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  Journal of medicinal chemistry 20050811

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  Journal of colloid and interface science 20050715

• Toward improving the chemistry of N-acyliminium ions: nucleophilic substitution reactions of pyrrolidinone derivatives with trialkylsilyl nucleophiles catalyzed by triisopropylsilyltrifluoromethane sulfonate (TIPSOTf).

  Organic letters 20050707

• Lead exposure inhibits fracture healing and is associated with increased chondrogenesis, delay in cartilage mineralization, and a decrease in osteoprogenitor frequency.

  Environmental health perspectives 20050601

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  Intensive care medicine 20050501

• Preclinical evaluation of the pharmacodynamic properties of 2,5-diaziridinyl-3-hydroxymethyl-6-methyl-1,4-benzoquinone.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050401

• The synthesis of (-)-isodomoic acid C.

  Journal of the American Chemical Society 20050302

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  Journal of pharmaceutical sciences 20050301

• Skin permeation of propranolol from polymeric film containing terpene enhancers for transdermal use.

  International journal of pharmaceutics 20050131

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  International journal of pharmaceutics 20050120

• CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological evaluation of piperidine-4-carboxamide derivatives.

  Bioorganic & medicinal chemistry 20050117

• Optimization of pyrrolidinone based HIV protease inhibitors.

  Bioorganic & medicinal chemistry letters 20050103

• Rapid, single-tube method for quantitative preparation and analysis of RNA and DNA in samples as small as one cell.

  BMC biotechnology 20050101

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  Journal of nanobiotechnology 20050101

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  Drug delivery 20050101

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  BMC plant biology 20050101

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  Clinical and molecular allergy : CMA 20050101

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  BMC plant biology 20050101

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  BMC genomics 20050101

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  Angewandte Chemie (International ed. in English) 20041217

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  Bioorganic & medicinal chemistry letters 20041115

• Regioselectivity in iron-catalyzed [2+2+1] cycloadditions: a DFT investigation of substituent effects in 1,4-diazabutadienes.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20041105

• Rapid induction of splenic and peritoneal B-1a cells in adult mice by thymus-independent type-2 antigen.

  Journal of immunology (Baltimore, Md. : 1950) 20041101

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  Genome 20041001

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  Chemical & pharmaceutical bulletin 20040901

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  NMR in biomedicine 20040801

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  Bioorganic & medicinal chemistry letters 20040716

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  Macromolecular bioscience 20040714

• Rapid dissolution of high-potency danazol particles produced by evaporative precipitation into aqueous solution.

  Journal of pharmaceutical sciences 20040701

• Molecular dynamics study of the interactions of ice inhibitors on the ice {001} surface.

  Langmuir : the ACS journal of surfaces and colloids 20040622

• Mechanism of growth of colloidal silver nanoparticles stabilized by polyvinyl pyrrolidone in gamma-irradiated silver nitrate solution.

  Journal of colloid and interface science 20040601

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  Chemical communications (Cambridge, England) 20040521

• The effect of dehydration history on PVA/PVP hydrogels for nucleus pulposus replacement.

  Journal of biomedical materials research. Part B, Applied biomaterials 20040515

• Micelles from lipid derivatives of water-soluble polymers as delivery systems for poorly soluble drugs.

  Advanced drug delivery reviews 20040507

• Lactams as EP4 prostanoid receptor subtype selective agonists. Part 1: 2-Pyrrolidinones-stereochemical and lower side-chain optimization.

  Bioorganic & medicinal chemistry letters 20040405

• Penetration enhancers.

  Advanced drug delivery reviews 20040327

• Comparative pharmacokinetics and metabolism of levetiracetam, a new anti-epileptic agent, in mouse, rat, rabbit and dog.

  Xenobiotica; the fate of foreign compounds in biological systems 20040301

• Properties and biocompatibility of polypropylene graft copolymer films.

  Journal of biomedical materials research. Part B, Applied biomaterials 20040215

• Process and formulation variables affecting the performance of a rupturable capsule-based drug delivery system with pulsatile drug release.

  Drug development and industrial pharmacy 20040201

• Discovery of 4-substituted pyrrolidone butanamides as new agents with significant antiepileptic activity.

  Journal of medicinal chemistry 20040129

• Polyvinylpyrrolidone-drug conjugate: synthesis and release mechanism.

  Journal of controlled release : official journal of the Controlled Release Society 20040108

• Vitrification of bovine oocytes and its application to intergeneric somatic cell nucleus transfer.

  Theriogenology 20040101

• CCR5 antagonists as anti-HIV-1 agents. 1. Synthesis and biological evaluation of 5-oxopyrrolidine-3-carboxamide derivatives.

  Chemical & pharmaceutical bulletin 20040101

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  Eksperimental'naia i klinicheskaia farmakologiia 20040101

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  Cell transplantation 20040101

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  Eksperimental'naia i klinicheskaia farmakologiia 20040101

• Development of matrix-membrane transdermal drug delivery system for atenolol.

  Drug delivery 20040101

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  Bioorganic & medicinal chemistry letters 20031215

• Dioxygen-coupled oxidative amination of styrene.

  Journal of the American Chemical Society 20031029

• Mucoadhesive buccal patches of miconazole nitrate: in vitro/in vivo performance and effect of ageing.

  International journal of pharmaceutics 20031002

• Developmental outcome of levetiracetam, its major metabolite in humans, 2-pyrrolidinone N-butyric acid, and its enantiomer (R)-alpha-ethyl-oxo-pyrrolidine acetamide in a mouse model of teratogenicity.

  Epilepsia 20031001

• Formation of vinylogous compounds in model Maillard reaction systems.

  Chemical research in toxicology 20031001

• Enhanced bleomycin-induced pulmonary damage in mice lacking extracellular superoxide dismutase.

  Free radical biology & medicine 20031001

• Evaluation of critical formulation factors in the development of a rapidly dispersing captopril oral dosage form.

  Drug development and industrial pharmacy 20031001

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  Brain research. Molecular brain research 20030910

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  Acta crystallographica. Section C, Crystal structure communications 20030901

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  Farmaco (Societa chimica italiana : 1989) 20030901

• Vibrational and electronic couplings in ultraviolet resonance Raman spectra of cyclic peptides.

  Biophysical chemistry 20030901

• Chemical and olfactory characterization of odorous compounds and their precursors in the parotoid gland secretion of the green tree frog, Litoria caerulea.

  Journal of chemical ecology 20030901

• Design and characterization of mucoadhesive buccal patches containing cetylpyridinium chloride.

  Acta pharmaceutica (Zagreb, Croatia) 20030901

• Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: modifications of essential pyrrolidinone ring substituents.

  Bioorganic & medicinal chemistry 20030703

• Dichloroketene-chiral olefin-based approach to pyrrolizidines: highly stereocontrolled synthesis of (+)-amphorogynine A.

  Organic letters 20030515

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  Chemistry (Weinheim an der Bergstrasse, Germany) 20030303

• Pyroglutamyl-peptidase I: cloning, sequencing, and characterisation of the recombinant human enzyme.

  Protein expression and purification 20030301

• A study of 5-aminolevulinic acid and its methyl ester used in in vitro and in vivo systems of human bladder cancer.

  International journal of oncology 20030201

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  Eksperimental'naia i klinicheskaia farmakologiia 20030101

• Source reduction for prevention of methylene chloride hazards: cases from four industrial sectors.

  Environmental health : a global access science source 20030101

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  Journal of chemical information and computer sciences 20030101

• Pyrrolidonyl and pyridyl alkaloids in Lymantria dispar.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101

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  Eksperimental'naia i klinicheskaia farmakologiia 20030101

• Development and in-vitro evaluation of sustained release poloxamer 407 (P407) gel formulations of ceftiofur.

  Journal of controlled release : official journal of the Controlled Release Society 20021213

• Novel spirocyclic pyrrolidones as P2/P1 mimetics in potent inhibitors of HIV-1 protease.

  Bioorganic & medicinal chemistry letters 20021202

• Design of inhibitors of scytalone dehydratase: probing interactions with an asparagine carboxamide.

  Bioorganic & medicinal chemistry 20021201

• GABA and glutamate in the human brain.

  The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 20021201

• Nefiracetam induces a long-lasting facilitation of hippocampal postsynaptic responses in mice lacking the NMDA receptor epsilon1 subunit.

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  Journal of the American Chemical Society 20021113

• N-Arylated pyrrolidin-2-ones and morpholin-3-ones as potassium channel openers.

  Bioorganic & medicinal chemistry 20021001

• Influence of storage time and temperature on the stability of indomethacin Pluronic F-127 gels.

  Die Pharmazie 20021001

• Radical carboazidation of alkenes: an efficient tool for the preparation of pyrrolidinone derivatives.

  Angewandte Chemie (International ed. in English) 20020916

• Evaluation of solid dispersions of Clofazimine.

  Drug development and industrial pharmacy 20020901

• Geographic variation of natural products of tropical nudibranch Asteronotus cespitosus.

  Journal of chemical ecology 20020901

• Palladium-catalyzed aminoallylation of activated olefins with allylic halides and phthalimide.

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  Organic letters 20020808

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  Toxicology letters 20020805

• Novel potent 5-HT(3) receptor ligands based on the pyrrolidone structure. Effects of the quaternization of the basic nitrogen on the interaction with 5-HT(3) receptor.

  Bioorganic & medicinal chemistry 20020801

• Transdermal delivery of physostigmine: effects of enhancers and pressure-sensitive adhesives.

  Drug development and industrial pharmacy 20020801

• Acylating agents as enzyme inhibitors and understanding their reactivity for drug design.

  Journal of medicinal chemistry 20020620

• Induction of endothelial cell apoptosis by the antivascular agent 5,6-Dimethylxanthenone-4-acetic acid.

  British journal of cancer 20020617

• Effect of water on the molecular mobility of sucrose and poly(vinylpyrrolidone) in a colyophilized formulation as measured by (13)C-NMR relaxation time.

  Chemical & pharmaceutical bulletin 20020601

• Acetylenic polymers for hair styling products.

  International journal of cosmetic science 20020601

• Interaction of influenza A virus M1 matrix protein with caspases.

  Biochemistry. Biokhimiia 20020501

• Effect of the absence or presence of various protein supplements on further development of bovine oocytes during in vitro maturation.

  Biology of reproduction 20020401

• Novel potent 5-HT(3) receptor ligands based on the pyrrolidone structure: synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities.

  Bioorganic & medicinal chemistry 20020301

• BAL 9141, a new broad-spectrum pyrrolidinone cephalosporin: activity against clinically significant anaerobes in comparison with 10 other antimicrobials.

  The Journal of antimicrobial chemotherapy 20020301

• Evaluation of CC2 as a decontaminant in various hydrophilic and lipophilic formulations against sulphur mustard.

  Biomedical and environmental sciences : BES 20020301

• Penicillin-resistant Aerococcus viridans bacteremia associated with granulocytopenia.

  Journal of Korean medical science 20020201

• The aniracetam metabolite 2-pyrrolidinone induces a long-term enhancement in AMPA receptor responses via a CaMKII pathway.

  Brain research. Molecular brain research 20020131

• Catalytic asymmetric intramolecular aminopalladation: enantioselective synthesis of vinyl-substituted 2-oxazolidinones, 2-imidazolidinones, and 2-pyrrolidinones.

  Journal of the American Chemical Society 20020109

• Regional differences in expression of VEGF mRNA in rat gastrocnemius following 1 hr exercise or electrical stimulation.

  BMC physiology 20020101

• [Effect of a drug composition containing pyroglutamic acid and pyrrolidone on the cerebral circulation].

  Eksperimental'naia i klinicheskaia farmakologiia 20020101

• Electrophilic fluorination of pyroglutamic acid derivatives: application of substrate-dependent reactivity and diastereoselectivity to the synthesis of optically active 4-fluoroglutamic acids.

  The Journal of organic chemistry 20011228

• Synthesis and characterization of tetramethylrhodaminethiocarbamoyl-(Glu(1))-epidermal mitosis-inhibiting pentapeptide.

  Regulatory peptides 20011215

• Pyrrolidone derivatives.

  Lancet (London, England) 20011201

• Amphiphilic poly-N-vinylpyrrolidones: synthesis, properties and liposome surface modification.

  Biomaterials 20011101

• The effect of polyvinyl pyrrolidone on the clinical activity of 0.09% and 0.2% chlorhexidine mouthrinses.

  Journal of clinical periodontology 20011101

• Antidepressant-like effects of aniracetam in aged rats and its mode of action.

  Psychopharmacology 20011101

• Degradation of imidacloprid in water by photo-Fenton and TiO2 photocatalysis at a solar pilot plant: a comparative study.

  Environmental science & technology 20011101

• Characterization of the solubility and dissolution properties of several new rifampicin polymorphs, solvates, and hydrates.

  Drug development and industrial pharmacy 20011101

• Aniracetam enhances cortical dopamine and serotonin release via cholinergic and glutamatergic mechanisms in SHRSP.

  Brain research 20011019

• Synthesis of valproic acid amides of a melatonin derivative, a piracetam and amantadine for biological tests.

  Neurochemical research 20011001

• Extraction of human DNA for PCR from chewed residues of betel quid using a novel 'PVP/CTAB' method.

  Journal of forensic sciences 20010901

• Influences of alkyl group chain length and polar head group on chemical skin permeation enhancement.

  Journal of pharmaceutical sciences 20010801

• Influence of fluorophor dye labels on the migration behavior of polymerase chain reaction--amplified short tandem repeats during denaturing capillary electrophoresis.

  Electrophoresis 20010801

• A comparison of alternative polymer excipients and processing methods for making solid dispersions of a poorly water soluble drug.

  International journal of pharmaceutics 20010703

• Fourier transform Raman spectroscopic study of the interaction of water vapor with amorphous polymers.

  Journal of pharmaceutical sciences 20010701

• Pharmacokinetics of levetiracetam and its enantiomer (R)-alpha-ethyl-2-oxo-pyrrolidine acetamide in dogs.

  Epilepsia 20010701

• Synthesis of ent-alantrypinone.

  Journal of the American Chemical Society 20010627

• Studies on the effect of polyvinyl pyrrolidone on the activity of chlorhexidine mouthrinses: plaque and stain.

  Journal of clinical periodontology 20010601

• Control and stability of drug release from diffusion pellets coated with the aqueous quaternary polymethacrylate dispersion Eudragit RS 30 D.

  Die Pharmazie 20010601

• The design of competitive, small-molecule inhibitors of coagulation factor Xa.

  Current topics in medicinal chemistry 20010601

• The mechanism of aubstrate eecognition of pyroglutamyl-peptidase I from Bacillus amyloliquefaciens as determined by X-ray crystallography and site-directed mutagenesis.

  The Journal of biological chemistry 20010525

• Design and synthesis of 2-oxo-imidazolidine-4-carboxylic acid hydroxyamides as potent matrix metalloproteinase-13 inhibitors.

  Bioorganic & medicinal chemistry letters 20010507

• Full term development of rabbit oocytes fertilized by intracytoplasmic sperm injection.

  Molecular reproduction and development 20010501

• Efficacy of topical phenol decontamination strategies on severity of acute phenol chemical burns and dermal absorption: in vitro and in vivo studies in pig skin.

  Toxicology and industrial health 20010501

• Removal of N-terminal blocking groups from proteins.

  Current protocols in protein science 20010501

• In vivo assessment of enhanced topical delivery of terbinafine to human stratum corneum.

  Journal of controlled release : official journal of the Controlled Release Society 20010428

• Rational design, synthesis, and biological evaluation of rigid pyrrolidone analogues as potential inhibitors of prostate cancer cell growth.

  Bioorganic & medicinal chemistry letters 20010423

• Single molecule DNA sequencing in submicrometer channels: state of the art and future prospects.

  Journal of biotechnology 20010413

• Site-specific activation of dopamine and serotonin transmission by aniracetam in the mesocorticolimbic pathway of rats.

  Brain research 20010406

• A pyrrolidinone derivative inhibits cytokine-induced iNOS expression and NF-kappaB activation by preventing phosphorylation and degradation of IkappaB-alpha.

  Journal of biochemistry 20010401

• Solvent effects on dimeric self-association of 2-pyrrolidinone: an ab initio study.

  Journal of computer-aided molecular design 20010401

• Topiramate rapidly raises brain GABA in epilepsy patients.

  Epilepsia 20010401

• Homocarnosine and seizure control in juvenile myoclonic epilepsy and complex partial seizures.

  Neurology 20010327

• Synthesis of pyrrolidinone PNA: a novel conformationally restricted PNA analogue.

  The Journal of organic chemistry 20010209

• Separation of multicomponent mixtures of 2,4-dinitrophenyl labelled amino acids and their enantiomers by capillary zone electrophoresis.

  Electrophoresis 20010201

• Crystallization of hydrocortisone acetate: influence of polymers.

  International journal of pharmaceutics 20010116

• Selected reaction monitoring LC-MS determination of idoxifene and its pyrrolidinone metabolite in human plasma using robotic high-throughput, sequential sample injection.

  Analytical chemistry 20010101

• Fusogenic activity of vesicular stomatitis virus glycoprotein plasmid in tumors as an enhancer of IL-12 gene therapy.

  Cancer gene therapy 20010101

• Characterization of protein-loaded poly(epsilon-caprolactone) microparticles based on a factorial design.

  Journal of microencapsulation 20010101

• Optimization of DNA electrophoretic behavior in poly(vinyl pyrrolidone) sieving matrix for DNA sequencing.

  Electrophoresis 20010101

• Rapid single nucleotide polymorphism analysis by primer extension and capillary electrophoresis using polyvinyl pyrrolidone matrix.

  Electrophoresis 20010101

• Nefiracetam improves Morris water maze performance following traumatic brain injury in rats.

  Pharmacology, biochemistry, and behavior 20010101

• Identification of odoriferous compounds from adults of a swallowtail butterfly, Papilio machaon (Lepidoptera: Papilionidae).

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101

• Properties of polyvinyl pyrrolidone/beta-chitosan hydrogel membranes and their biocompatibility evaluation by haemorheological method.

  Journal of materials science. Materials in medicine 20010101