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Activation of melatonin receptor (MT1/2) promotes P-gp transporter in methamphetamine-induced toxicity on primary rat brain microvascular endothelial cells.
Toxicology in vitro : an international journal published in association with BIBRA 20170601
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Multi-drug resistance in a canine lymphoid cell line due to increased P-glycoprotein expression, a potential model for drug-resistant canine lymphoma.
Toxicology in vitro : an international journal published in association with BIBRA 20141201
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CEP-33779 antagonizes ATP-binding cassette subfamily B member 1 mediated multidrug resistance by inhibiting its transport function.
Biochemical pharmacology 20140915
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The inhibitory and combinative mechanism of HZ08 with P-glycoprotein expressed on the membrane of Caco-2 cell line.
Toxicology and applied pharmacology 20140115
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Oroxylin A reverses P-glycoprotein-mediated multidrug resistance of MCF7/ADR cells by G2/M arrest.
Toxicology letters 20130523
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Reversal of P-glycoprotein-mediated multidrug resistance is induced by mollugin in MCF-7/adriamycin cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology 20130515
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Novel codrugs with GABAergic activity for dopamine delivery in the brain.
International journal of pharmaceutics 20121101
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Amphiphilic HPMA-LMA copolymers increase the transport of Rhodamine 123 across a BBB model without harming its barrier integrity.
Journal of controlled release : official journal of the Controlled Release Society 20121028
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Polyethylenimine-capped Ag nanoparticle film as a platform for detecting charged dye molecules by surface-enhanced Raman scattering and metal-enhanced fluorescence.
ACS applied materials & interfaces 20121024
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Influence of P-glycoprotein on brucine transport at the in vitro blood-brain barrier.
European journal of pharmacology 20120905
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The novel BCR-ABL and FLT3 inhibitor ponatinib is a potent inhibitor of the MDR-associated ATP-binding cassette transporter ABCG2.
Molecular cancer therapeutics 20120901
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Lipopolysaccharide-activated microglia lower P-glycoprotein function in brain microvascular endothelial cells.
Neuroscience letters 20120822
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Inhibition of P-glycoprotein functionality by vandetanib may reverse cancer cell resistance to doxorubicin.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120815
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In vitro P-glycoprotein efflux inhibition by atypical antipsychotics is in vivo nicely reflected by pharmacodynamic but less by pharmacokinetic changes.
Pharmacology, biochemistry, and behavior 20120801
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Zosuquidar and an albumin-binding prodrug of zosuquidar reverse multidrug resistance in breast cancer cells of doxorubicin and an albumin-binding prodrug of doxorubicin.
Breast cancer research and treatment 20120701
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Crizotinib (PF-02341066) reverses multidrug resistance in cancer cells by inhibiting the function of P-glycoprotein.
British journal of pharmacology 20120701
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Evaluation of the relationship between [18F]FDG and P-glycoprotein expression: an experimental study.
Nuclear medicine and biology 20120701
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Solid lipid nanoparticles as intracellular drug transporters: an investigation of the uptake mechanism and pathway.
International journal of pharmaceutics 20120701
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Potential P-glycoprotein-mediated drug-drug interactions of antimalarial agents in Caco-2 cells.
The American journal of tropical medicine and hygiene 20120701
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The effects of notoginsenoside R₁ on the intestinal absorption of geniposide by the everted rat gut sac model.
Journal of ethnopharmacology 20120626
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Expression and activity of p-glycoprotein elevated by dexamethasone in cultured retinal pigment epithelium involve glucocorticoid receptor and pregnane X receptor.
Investigative ophthalmology & visual science 20120608
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Effects of gelucire content on stability, macrophage interaction and blood circulation of nanoparticles engineered from nanoemulsions.
Colloids and surfaces. B, Biointerfaces 20120601
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Suppression of efflux transporters in the intestines of endotoxin-treated rats.
International journal of pharmaceutics 20120530
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Effects of cysteine on the pharmacokinetics of docetaxel in rats with protein-calorie malnutrition.
Xenobiotica; the fate of foreign compounds in biological systems 20120501
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Whole-object fluorescence lifetime setup for efficient non-imaging quantitative intracellular fluorophore measurements.
Journal of fluorescence 20120501
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Synthesis and biological evaluation of novel bifendate derivatives bearing 6,7-dihydro-dibenzo[c,e]azepine scaffold as potent P-glycoprotein inhibitors.
European journal of medicinal chemistry 20120501
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Application of a homogenous membrane potential assay to assess mitochondrial function.
Physiological genomics 20120501
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Blood-brain barrier in vitro models as tools in drug discovery: assessment of the transport ranking of antihistaminic drugs.
Die Pharmazie 20120501
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[Correlation between reversing effect of cepharanthine hydrochloride on multidrug resistance and P-glycoprotein expression and function of K562/ADR cells].
Yao xue xue bao = Acta pharmaceutica Sinica 20120501
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Nanosecond electric pulses cause mitochondrial membrane permeabilization in Jurkat cells.
Bioelectromagnetics 20120401
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Effects of myricetin on the bioavailability of carvedilol in rats.
Pharmaceutical biology 20120401
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A pharmacodynamic study of the P-glycoprotein antagonist CBT-1® in combination with paclitaxel in solid tumors.
The oncologist 20120401
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Etoposide modulates the effects of oral morphine analgesia by targeting the intestinal P-glycoprotein.
The Journal of pharmacy and pharmacology 20120401
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[Evaluation of P-glycoprotein mediated in vitro loperamide biliary excretion with sandwich-cultured rat hepatocytes model].
Yao xue xue bao = Acta pharmaceutica Sinica 20120401
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Reversal of P-glycoprotein-mediated multidrug resistance by a synthetic α-aminoxy peptidomimetic.
International journal of pharmaceutics 20120315
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Real-time analysis of P-glycoprotein-mediated drug transport across primary intestinal epithelium three-dimensionally cultured in vitro.
Biochemical and biophysical research communications 20120309
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ABCG2-overexpressing S1-M1-80 cell xenografts in nude mice keep original biochemistry and cell biological properties.
Chinese journal of cancer 20120301
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The effect of clotrimazole on energy substrate uptake and carcinogenesis in intestinal epithelial cells.
Anti-cancer drugs 20120201
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Effects of efonidipine on the pharmacokinetics and pharmacodynamics of repaglinide: possible role of CYP3A4 and P-glycoprotein inhibition by efonidipine.
Journal of pharmacokinetics and pharmacodynamics 20120201
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Effects of curcumin on the pharmacokinetics of tamoxifen and its active metabolite, 4-hydroxytamoxifen, in rats: possible role of CYP3A4 and P-glycoprotein inhibition by curcumin.
Die Pharmazie 20120201
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Nanohybrid systems of non-ionic surfactant inserting liposomes loading paclitaxel for reversal of multidrug resistance.
International journal of pharmaceutics 20120117
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HEC-cysteamine conjugates: influence of degree of thiolation on efflux pump inhibitory and permeation enhancing properties.
International journal of pharmaceutics 20120117
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Kuguacin J isolated from Momordica charantia leaves inhibits P-glycoprotein (ABCB1)-mediated multidrug resistance.
The Journal of nutritional biochemistry 20120101
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Mechanistic studies of the effect of bile salts on rhodamine 123 uptake into RBE4 cells.
Molecular pharmaceutics 20120101
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Fluorescence measurement of mitochondrial membrane potential changes in cultured cells.
Methods in molecular biology (Clifton, N.J.) 20120101
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Uptake characteristics of pinocembrin and its effect on p-glycoprotein at the blood-brain barrier in in vitro cell experiments.
Journal of Asian natural products research 20120101
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Spray-dried microparticles: a potential vehicle for oral delivery of vaccines.
Journal of microencapsulation 20120101
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Characterization of rhodamine-123 as a tracer dye for use in in vitro drug transport assays.
PloS one 20120101
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Effects of in vivo hepatic ischemia-reperfusion injury on the hepatobiliary disposition of rhodamine 123 and its metabolites in isolated perfused rat livers.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20120101
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Partial synthesis and biological evaluation of bisbenzylisoquinoline alkaloids derivatives: potential modulators of multidrug resistance in cancer.
Journal of Asian natural products research 20120101
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Effects of lipid-probe interactions in biochemical fluorometric methods that assess HDL redox activity.
Lipids in health and disease 20120101
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CB2 and TRPV1 receptors mediate cannabinoid actions on MDR1 expression in multidrug resistant cells.
Pharmacological reports : PR 20120101
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Impact of small molecules immunosuppressants on P-glycoprotein activity and T-cell function.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20120101
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Determination of Rhodamine 123 in rat plasma utilizing liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111215
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YC-1, a novel potential anticancer agent, inhibit multidrug-resistant protein via cGMP-dependent pathway.
Investigational new drugs 20111201
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Biochemical mechanism of modulation of human P-glycoprotein by stemofoline.
Planta medica 20111201
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Effect of knockdown of ezrin, radixin, and moesin on P-glycoprotein function in HepG2 cells.
Journal of pharmaceutical sciences 20111201
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A biochemical fluorometric method for assessing the oxidative properties of HDL.
Journal of lipid research 20111201
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An in vitro transport model for rapid screening and predicting the permeability of candidate compounds at blood-brain barrier.
Journal of Asian natural products research 20111201
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Modelling the neurovascular unit and the blood-brain barrier with the unique function of pericytes.
Current neurovascular research 20111101
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Development of a double-layer microfluidic chip with flow medium for chemotherapy resistance analysis of lung cancer.
Electrophoresis 20111101
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Beta amyloid effects on expression of multidrug efflux transporters in brain endothelial cells.
Brain research 20111018
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Highly biocompatible TiO₂:Gd³⁺ nano-contrast agent with enhanced longitudinal relaxivity for targeted cancer imaging.
Nanoscale 20111005
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Mitochondrial targeting for photochemotherapy. Can selective tumor cell killing be predicted based on n-octanol/water distribution coefficients?
Biotechnic & histochemistry : official publication of the Biological Stain Commission 20111001
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Synthesis and evaluation of furoxan-based nitric oxide-releasing derivatives of tetrahydroisoquinoline as anticancer and multidrug resistance reversal agents.
Bioorganic & medicinal chemistry letters 20111001
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Modulation of multidrug efflux pump activity by new hydantoin derivatives on colon adenocarcinoma cells without inducing apoptosis.
Anticancer research 20111001
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Development of fluorescence imaging-based assay for screening cardioprotective compounds from medicinal plants.
Analytica chimica acta 20110919
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Methamphetamine-mediated modulation of MOR expression in the SH-SY5Y neuroblastoma cell line.
Synapse (New York, N.Y.) 20110901
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Influence of detergents on the activity of the ABC transporter LmrA.
Biochimica et biophysica acta 20110901
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Characterization of rhodamine-123, calcein and 5(6)-carboxy-2',7'-dichlorofluorescein (CDCF) export via MRP2 (ABCC2) in MES-SA and A549 cells.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110817
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The effect of vitamin D3 and ketoconazole combination on VDR-mediated P-gp expression and function in human colon adenocarcinoma cells: implications in drug disposition and resistance.
Basic & clinical pharmacology & toxicology 20110801
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Effects of chronic renal failure on kidney drug transporters and cytochrome P450 in rats.
Drug metabolism and disposition: the biological fate of chemicals 20110801
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Poloxamines display a multiple inhibitory activity of ATP-binding cassette (ABC) transporters in cancer cell lines.
Molecular pharmaceutics 20110801
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The role of paclitaxel in the development and treatment of multidrug resistant cancer cell lines.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20110801
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Pregnane X receptor mediates the induction of P-glycoprotein by spironolactone in HepG2 cells.
Toxicology 20110711
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Effects of borneol on the intestinal transport and absorption of two P-glycoprotein substrates in rats.
Archives of pharmacal research 20110701
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Design and synthesis of a novel cationic thiolated polymer.
International journal of pharmaceutics 20110615
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Reversal effects of two new milbemycin compounds on multidrug resistance in MCF-7/adr cells in vitro.
European journal of pharmacology 20110601
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Thiolated chitosans: influence of various sulfhydryl ligands on permeation-enhancing and P-gp inhibitory properties.
Drug development and industrial pharmacy 20110601
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H1, a novel derivative of tetrandrine reverse P-glycoprotein-mediated multidrug resistance by inhibiting transport function and expression of P-glycoprotein.
Cancer chemotherapy and pharmacology 20110501
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Induction of drug efflux protein expression by venlafaxine but not desvenlafaxine.
Biopharmaceutics & drug disposition 20110501
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Effects of oral curcumin on the pharmacokinetics of intravenous and oral etoposide in rats: possible role of intestinal CYP3A and P-gp inhibition by curcumin.
Biopharmaceutics & drug disposition 20110501
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Euphorbia factor L1 reverses ABCB1-mediated multidrug resistance involving interaction with ABCB1 independent of ABCB1 downregualtion.
Journal of cellular biochemistry 20110401
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Proapoptotic activity in vitro of two novel ruthenium(II) complexes with flavanone-based ligands that overcome cisplatin resistance in human bladder carcinoma cells.
Journal of inorganic biochemistry 20110401
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Polyethylenimine/oligonucleotide polyplexes investigated by fluorescence resonance energy transfer and fluorescence anisotropy.
Oligonucleotides 20110401
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[Nitric oxide synthase-mediated alteration of intestinal P-glycoprotein under hyperglycemic stress].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110401
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Investigation on mechanisms of glycopeptide nanoparticles for drug delivery across the blood-brain barrier.
Nanomedicine (London, England) 20110401
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Stavudine entrapped lipid nanoparticles for targeting lymphatic HIV reservoirs.
Die Pharmazie 20110401
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Molecular dissection of dual pseudosymmetric solute translocation pathways in human P-glycoprotein.
Molecular pharmacology 20110301
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Expression and functional activity of P-glycoprotein in passaged primary human nasal epithelial cell monolayers cultured by the air-liquid interface method for nasal drug transport study.
The Journal of pharmacy and pharmacology 20110301
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Effect of BIBF 1120 on reversal of ABCB1-mediated multidrug resistance.
Cellular oncology (Dordrecht) 20110201
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Cell activity analysis by capillary zone electrophoresis combined with specific cell staining.
Electrophoresis 20110201
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Loperamide, an FDA-approved antidiarrhea drug, effectively reverses the resistance of multidrug resistant MCF-7/MDR1 human breast cancer cells to doxorubicin-induced cytotoxicity.
Cancer investigation 20110201
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Marking live conifer pollen for long-distance dispersal experiments.
Oecologia 20110101
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Marking live conifer pollen for long-distance dispersal experiments.
Oecologia 20110101
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Reversion of resistance to immunosuppressive agents in three patients with psoriatic arthritis by cyclosporine A: modulation of P-glycoprotein function.
Clinical immunology (Orlando, Fla.) 20110101
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Divergent effects of nitric oxide donors on the biliary efflux transporters in isolated perfused rat livers: nitric oxide-independent inhibition of ABC transporters by sodium nitroprusside.
Drug metabolism letters 20110101
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In vitro ultraviolet-induced damage in human corneal, lens, and retinal pigment epithelial cells.
Molecular vision 20110101
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Reversal of multidrug resistance by guggulsterone in drug-resistant MCF-7 cell lines.
Chemotherapy 20110101
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Photodynamic effects of pterin on HeLa cells.
Photochemistry and photobiology 20110101
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Therapy with sodium stibogluconate in stearylamine-bearing liposomes confers cure against SSG-resistant Leishmania donovani in BALB/c mice.
PloS one 20110101
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Effects of HMG-CoA reductase inhibitors on the pharmacokinetics of losartan and its main metabolite EXP-3174 in rats: possible role of CYP3A4 and P-gp inhibition by HMG-CoA reductase inhibitors.
Pharmacology 20110101
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Arsenic trioxide plus cisplatin/interferon α-2b/doxorubicin/capecitabine combination chemotherapy for unresectable hepatocellular carcinoma.
Hematology/oncology and stem cell therapy 20110101
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Exposure of LS-180 cells to drugs of diverse physicochemical and therapeutic properties up-regulates P-glycoprotein expression and activity.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20110101
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Using rhodamine 123 accumulation in CD8 cells as a surrogate indicator to study the P-glycoprotein modulating effect of cepharanthine hydrochloride in vivo.
Journal of biomedicine & biotechnology 20110101
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Overcoming of P-glycoprotein-mediated multidrug resistance in K562/A02 cells using riccardin F and pakyonol, bisbibenzyl derivatives from liverworts.
Bioscience trends 20110101
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Measurement of fluorescence in a rhodamine-123 doped self-assembled 'giant' mesostructured silica sphere using a smartphone as optical hardware.
Sensors (Basel, Switzerland) 20110101
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Effects of the multidrug resistance modulator HZ08 on the apoptosis pathway in human chronic leukaemia cell line K562/A02.
Arzneimittel-Forschung 20110101
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Pgp inhibition by UIC2 antibody can be followed in vitro by using tumor-diagnostic radiotracers, 99mTc-MIBI and 18FDG.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20101223
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A novel MDR1 GT1292-3TG (Cys431Leu) genetic variation and its effect on P-glycoprotein biologic functions.
The AAPS journal 20101201
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20(S)-ginsenoside Rh2 noncompetitively inhibits P-glycoprotein in vitro and in vivo: a case for herb-drug interactions.
Drug metabolism and disposition: the biological fate of chemicals 20101201
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Biological activity of hydantoin derivatives on P-glycoprotein (ABCB1) of mouse lymphoma cells.
Anticancer research 20101201
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The transport of gastrodin in Caco-2 cells and uptake in Bcap37 and Bcap37/MDR1 cells.
Yao xue xue bao = Acta pharmaceutica Sinica 20101201
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Selective accumulation of a novel antimalarial rhodacyanine derivative, SSJ-127, in an organelle of Plasmodium berghei.
Bioorganic & medicinal chemistry 20101115
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Neuroprotective effect of astaxanthin on H(2)O(2)-induced neurotoxicity in vitro and on focal cerebral ischemia in vivo.
Brain research 20101111
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The mechanism of vitexin-4''-O-glucoside protecting ECV-304 cells against tertbutyl hydroperoxide induced injury.
Natural product research 20101101
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Characterization of PXR mediated P-glycoprotein regulation in intestinal LS174T cells.
Pharmacological research 20101101
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Syl611, a novel semisynthetic taxane derivative, reverses multidrug resistance by p-glycoprotein inhibition and facilitating inward transmembrane action.
Cancer chemotherapy and pharmacology 20101001
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Time- and passage-dependent characteristics of a Calu-3 respiratory epithelial cell model.
Drug development and industrial pharmacy 20101001
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Design and in vitro evaluation of a novel polymeric P-glycoprotein (P-gp) inhibitor.
Journal of controlled release : official journal of the Controlled Release Society 20101001
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Bisbibenzyl derivatives sensitize vincristine-resistant KB/VCR cells to chemotherapeutic agents by retarding P-gp activity.
Bioorganic & medicinal chemistry 20100915
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Differences in assessment of macrolide interaction with human MDR1 (ABCB1, P-gp) using rhodamine-123 efflux, ATPase activity and cellular accumulation assays.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100911
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PXR-mediated induction of P-glycoprotein by anticancer drugs in a human colon adenocarcinoma-derived cell line.
Cancer chemotherapy and pharmacology 20100901
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Reversal of P-glycoprotein-mediated multidrug resistance in vitro by milbemycin compounds in adriamycin-resistant human breast carcinoma (MCF-7/adr) cells.
Toxicology in vitro : an international journal published in association with BIBRA 20100901
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Enhanced bioaccumulation of dietary contaminants in catfish with exposure to the waterborne surfactant linear alkylbenzene sulfonate.
Aquatic toxicology (Amsterdam, Netherlands) 20100815
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Chemical cytometry quantitates superoxide levels in the mitochondrial matrix of single myoblasts.
Analytical chemistry 20100815
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Interaction of anthelmintic drugs with P-glycoprotein in recombinant LLC-PK1-mdr1a cells.
Chemico-biological interactions 20100805
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MDR1 C2005T polymorphism changes substrate specificity.
Cancer chemotherapy and pharmacology 20100801
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In vitro and in vivo multidrug resistance reversal activity by a Betti-base derivative of tylosin.
British journal of cancer 20100713
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A novel calmodulin antagonist O-(4-ethoxyl-butyl)-berbamine overcomes multidrug resistance in drug-resistant MCF-7/ADR breast carcinoma cells.
Journal of pharmaceutical sciences 20100701
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Effects of silybinin, CYP3A4 and P-glycoprotein inhibitor in vitro, on the bioavailability of loratadine in rats.
Die Pharmazie 20100701
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Iodination increases the activity of verapamil derivatives in reversing PGP multidrug resistance.
Anticancer research 20100701
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Interaction of Naja naja atra cardiotoxin 3 with H-trisaccharide modulates its hemolytic activity and membrane-damaging activity.
Toxicon : official journal of the International Society on Toxinology 20100615
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In vitro concentration dependent transport of phenytoin and phenobarbital, but not ethosuximide, by human P-glycoprotein.
Life sciences 20100605
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Increased plasma exposures of five protoberberine alkaloids from Coptidis Rhizoma in streptozotocin-induced diabetic rats: is P-GP involved?
Planta medica 20100601
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Interaction of Rhei Rhizoma extract with cytochrome P450 3A and efflux transporters in rats.
Die Pharmazie 20100501
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Combined effects of epileptic seizure and phenobarbital induced overexpression of P-glycoprotein in brain of chemically kindled rats.
British journal of pharmacology 20100401
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[Modulation on the P-glycoprotein in the jejunum by combined use of Glycyrrhiza inflata and Kansui].
Yao xue xue bao = Acta pharmaceutica Sinica 20100401
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Multi-walled carbon nanotubes affect drug transport across cell membrane in rat astrocytes.
Nanotechnology 20100312
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Intact lipid rafts regulate HIV-1 Tat protein-induced activation of the Rho signaling and upregulation of P-glycoprotein in brain endothelial cells.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20100301
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A specific tumor-targeting magnetofluorescent nanoprobe for dual-modality molecular imaging.
Biomaterials 20100301
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Constituents of Carpobrotus edulis inhibit P-glycoprotein of MDR1-transfected mouse lymphoma cells.
Anticancer research 20100301
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Reversal of P-glycoprotein-mediated multidrug resistance in vitro by doramectin and nemadectin.
The Journal of pharmacy and pharmacology 20100301
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[Response of mouse macrophage cell line infected with Bacille Calmette-Guerin in vitro].
Wei sheng wu xue bao = Acta microbiologica Sinica 20100301
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Up-regulation of renal Mdr1 and Mrp2 transporters during amiodarone pretreatment in rats.
Pharmacological research 20100201
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Photodynamic properties of ZnTPPS(4), ClAlPcS(2) and ALA in human melanoma G361 cells.
Toxicology in vitro : an international journal published in association with BIBRA 20100201
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Metaxin deficiency alters mitochondrial membrane permeability and leads to resistance to TNF-induced cell killing.
Protein & cell 20100201
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Inhibition of P-glycoprotein activity by limonin and other secondary metabolites from Citrus species in human colon and leukaemia cell lines.
European journal of pharmacology 20100125
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Blood-brain barrier cell line PBMEC/C1-2 possesses functionally active P-glycoprotein.
Neuroscience letters 20100122
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Effects of P-glycoprotein and Mrp2 inhibitors on the hepatobiliary disposition of Rhodamine 123 and its glucuronidated metabolite in isolated perfused rat livers.
Journal of pharmaceutical sciences 20100101
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Regulation of BCRP (ABCG2) and P-glycoprotein (ABCB1) by cytokines in a model of the human blood-brain barrier.
Cellular and molecular neurobiology 20100101
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Overexpression of kinase-negative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction.
Diabetes 20100101
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Effects of Acanthopanax senticosus HARMS extract on drug transport in human intestinal cell line Caco-2.
Journal of natural medicines 20100101
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Effects of silybinin on the pharmacokinetics of tamoxifen and its active metabolite, 4-hydroxytamoxifen in rats.
Anticancer research 20100101
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Electrostatic interactions of fluorescent molecules with dielectric interfaces studied by total internal reflection fluorescence correlation spectroscopy.
International journal of molecular sciences 20100101
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Carbon nanotubes as intracellular carriers for multidrug resistant cells studied by capillary electrophoresis-laser-induced fluorescence.
Methods in molecular biology (Clifton, N.J.) 20100101
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Effect of Thai plant extracts on P-glycoprotein function and viability in paclitaxel-resistant HepG2 cells.
Drug metabolism and pharmacokinetics 20100101
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(3R,5S,7as)-(3,5-Bis(4-fluorophenyl)tetrahydro-1H-oxazolo[3,4-c]oxazol-7a-yl)methanol, a novel neuroprotective agent.
Journal of medicinal chemistry 20091210
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Nanoparticles as drug delivery agents specific for CNS: in vivo biodistribution.
Nanomedicine : nanotechnology, biology, and medicine 20091201
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Transplacental pharmacokinetics of glyburide, rhodamine 123, and BODIPY FL prazosin: effect of drug efflux transporters and lipid solubility.
The Journal of pharmacology and experimental therapeutics 20091201
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Investigation of the multixenobiotic resistance mechanism in the freshwater fishes western mosquitofish, Gambusia affinis, and bluegill sunfish, Lepomis macrochirus.
Bulletin of environmental contamination and toxicology 20091101
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Effect of cyclosporine on drug transport and pharmacokinetics of nifedipine.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20091101
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The effect of wellsolve, a novel solubilizing agent, on the intestinal barrier function and intestinal absorption of griseofulvin in rats.
Biological & pharmaceutical bulletin 20091101
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ABCC1, ABCC2 and ABCC3 are implicated in the transepithelial transport of the myco-estrogen zearalenone and its major metabolites.
Toxicology letters 20091028
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Cediranib (recentin, AZD2171) reverses ABCB1- and ABCC1-mediated multidrug resistance by inhibition of their transport function.
Cancer chemotherapy and pharmacology 20091001
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Effect of intestinal ischaemia/reperfusion on P-glycoprotein-mediated ileal excretion of rhodamine 123 in the rat.
The Journal of pharmacy and pharmacology 20091001
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Reversal of P-glycoprotein-mediated multidrug resistance by guggulsterone in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells.
Die Pharmazie 20091001
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Mitochondrial expression and functional activity of breast cancer resistance protein in different multiple drug-resistant cell lines.
Cancer research 20090915
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Cyclosporine diminishes multidrug resistance in K562/ADM cells and improves complete remission in patients with acute myeloid leukemia.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090901
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[ARTCEREB irrigation and perfusion solution for cerebrospinal surgery: pharmacological assessment using human astrocytes exposed to test solutions].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090901
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Effects of baicalein, an antioxidant, on the bioavailability of doxorubicin in rats: possible role of P-glycoprotein inhibition by baicalein.
Die Pharmazie 20090901
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New findings on melatonin absorption and alterations by pharmaceutical excipients using the Ussing chamber technique with mounted rat gastrointestinal segments.
International journal of pharmaceutics 20090813
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[Effect of liquorice decoction on rat intestinal P-glycoprotein].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090801
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Inhibition of P-glycoprotein function by procyanidine on blood-brain barrier.
Phytotherapy research : PTR 20090701
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Liposome composition is important for retention of liposomal rhodamine in P-glycoprotein-overexpressing cancer cells.
Drug delivery 20090701
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Glutathione depletion upregulates P-glycoprotein expression at the blood-brain barrier in rats.
The Journal of pharmacy and pharmacology 20090601
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MEKC-LIF analysis of rhodamine123 delivered by carbon nanotubes in K562 cells.
Electrophoresis 20090601
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Identification and expansion of human osteosarcoma-cancer-stem cells by long-term 3-aminobenzamide treatment.
Journal of cellular physiology 20090501
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A comparison of Zn2+- and Ca2+-triggered depolarization of liver mitochondria reveals no evidence of Zn2+-induced permeability transition.
Cell calcium 20090501
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Construction of a model cell line for the assay of MDR1 (multi drug resistance gene-1) substrates/inhibitors using HeLa cells.
Die Pharmazie 20090501
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Aged garlic extract stimulates p-glycoprotein and multidrug resistance associated protein 2 mediated effluxes.
Biological & pharmaceutical bulletin 20090401
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[Reversion of drug-resistant hepatocellular carcinoma cell line BEL-7402/FU by sorafenib].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20090401
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Inhibiting efflux with novel non-ionic surfactants: Rational design based on vitamin E TPGS.
International journal of pharmaceutics 20090331
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Reversal effect of substituted 1,3-dimethyl-1H-quinoxalin-2-ones on multidrug resistance in adriamycin-resistant K562/A02 cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090301
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Reversal of p-glycoprotein-mediated multidrug resistance by macrocyclic bisbibenzyl derivatives in adriamycin-resistant human myelogenous leukemia (K562/A02) cells.
Toxicology in vitro : an international journal published in association with BIBRA 20090201
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Development and characterisation of a new model of rat trophoblasts.
Toxicology in vitro : an international journal published in association with BIBRA 20090201
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Functionality of drug efflux pumps in antimonial resistant Leishmania donovani field isolates.
Indian journal of biochemistry & biophysics 20090201
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Reversal of P-glycoprotein-mediated multidrug resistance by the murine double minute 2 antagonist nutlin-3.
Cancer research 20090115
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2-Methoxyestradiol and multidrug resistance: can 2-methoxyestradiol chemosensitize resistant breast cancer cells?
Breast cancer research and treatment 20090101
-
Inhibition of P-glycoprotein-mediated paclitaxel resistance by reversibly linked quinine homodimers.
Molecular pharmacology 20090101
-
From delocalized lipophilic cations to hypoxia: blocking tumor cell mitochondrial function leads to therapeutic gain with glycolytic inhibitors.
Molecular nutrition & food research 20090101
-
A new blood-brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes.
Neurochemistry international 20090101
-
Effect of resveratrol on the pharmacokinetics of oral and intravenous nicardipine in rats: possible role of P-glycoprotein inhibition by resveratrol.
Die Pharmazie 20090101
-
Imatinib is a substrate for various multidrug resistance proteins.
Neoplasma 20090101
-
Antitumor activity of alkaloids derived from Amaryllidaceae species.
In vivo (Athens, Greece) 20090101
-
Live-cell imaging of the cytoskeleton and mitochondrial-cytoskeletal interactions in budding yeast.
Methods in molecular biology (Clifton, N.J.) 20090101
-
[P-glycoprotein functional activity in peripheral blood lymphocytes in ulcerative colitis].
Medicina 20090101
-
Paclitaxel-resistance conferred by altered expression of efflux and influx transporters for paclitaxel in the human hepatoma cell line, HepG2.
Drug metabolism and pharmacokinetics 20090101
-
Effects of intestinal ischemia/reperfusion on P-glycoprotein mediated biliary and renal excretion of rhodamine123 in rat.
Drug metabolism and pharmacokinetics 20090101
-
Differential effect of phenothiazines on MRP1 and P-glycoprotein activity.
In vivo (Athens, Greece) 20090101
-
Chemosensitizing effect of nordihydroguaiaretic acid and its tetra-acetylated derivative on parental and multiresistant TA3 mouse mammary adenocarcinoma cells.
In vivo (Athens, Greece) 20090101
-
Lymphocyte P-glycoprotein variability in healthy individuals.
Medicina 20090101
-
Different storing and processing conditions of human lymphocytes do not alter P-glycoprotein rhodamine 123 efflux.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20090101
-
Down-regulation of P-glycoprotein expression by sustained intracellular acidification in K562/Dox cells.
Biochemical and biophysical research communications 20081212
-
Evaluation of carbamazepine pharmacokinetic profiles in mice with kainic acid-induced acute seizures.
Biological & pharmaceutical bulletin 20081201
-
Simple, fast and high-throughput single-cell analysis on PDMS microfluidic chips.
Electrophoresis 20081201
-
Quinoline derivative KB3-1 potentiates paclitaxel induced cytotoxicity and cycle arrest via multidrug resistance reversal in MES-SA/DX5 cancer cells.
Life sciences 20081121
-
Human pharmaceuticals modulate P-gp1 (ABCB1) transport activity in the fish cell line PLHC-1.
Aquatic toxicology (Amsterdam, Netherlands) 20081121
-
P-glycoprotein (Abcb1) is involved in absorptive drug transport in skin.
Journal of controlled release : official journal of the Controlled Release Society 20081112
-
[Effect of Glycyrrhiza inflata and Daphne genkwa on permeabilities of rhodamine 123, a P-glycoprotein substrate across rat jejunum membranes in vitro].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081101
-
Solid lipid nanoparticles enhance the delivery of the HIV protease inhibitor, atazanavir, by a human brain endothelial cell line.
Pharmaceutical research 20081001
-
Delivery of nanoparticles to the brain detected by fluorescence microscopy.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20081001
-
Reversal effect of tyroservatide (YSV) tripeptide on multi-drug resistance in resistant human hepatocellular carcinoma cell line BEL-7402/5-FU.
Cancer letters 20080928
-
Lobeline, a piperidine alkaloid from Lobelia can reverse P-gp dependent multidrug resistance in tumor cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology 20080901
-
Interaction of coenzyme Q10 with the intestinal drug transporter P-glycoprotein.
Journal of agricultural and food chemistry 20080827
-
Rhodamine 123 efflux in human subpopulations of hematopoietic stem cells: comparison between bone marrow, umbilical cord blood and mobilized peripheral blood CD34+ cells.
International journal of molecular medicine 20080801
-
Enhanced oral bioavailability of paclitaxel by D-alpha-tocopheryl polyethylene glycol 400 succinate in mice.
International journal of pharmaceutics 20080709
-
Folate-functionalized polymeric micelles for tumor targeted delivery of a potent multidrug-resistance modulator FG020326.
Journal of biomedical materials research. Part A 20080701
-
Energy metabolism transition in multi-cellular human tumor spheroids.
Journal of cellular physiology 20080701
-
Effect of the novel antipsychotic drug perospirone on P-glycoprotein function and expression in Caco-2 cells.
European journal of clinical pharmacology 20080701
-
Effect of some P-glycoprotein modulators on Rhodamine-123 absorption in guinea-pig ileum.
Bioorganic & medicinal chemistry letters 20080701
-
Curcuma drugs and curcumin regulate the expression and function of P-gp in Caco-2 cells in completely opposite ways.
International journal of pharmaceutics 20080624
-
Detection of de- and hyperpolarization of mitochondria of cultured astrocytes and neurons by the cationic fluorescent dye rhodamine 123.
Journal of neuroscience methods 20080615
-
Trans- and cis-stilbene polyphenols induced rapid perinuclear mitochondrial clustering and p53-independent apoptosis in cancer cells but not normal cells.
European journal of pharmacology 20080610
-
Apoptosis-inducing effects of two anthraquinones from Hedyotis diffusa WILLD.
Biological & pharmaceutical bulletin 20080601
-
Reversal of P-glycoprotein and multidrug resistance-associated protein 1 mediated multidrug resistance in cancer cells by HZ08 Isomers, tetrataisohydroquinolin derivatives.
Biological & pharmaceutical bulletin 20080601
-
Inhibitory activity of nuclear factor-kappaB potentiates cisplatin-induced apoptosis in A549 cells.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20080601
-
In vitro and in vivo study of CJY, an isoflavone, on p-glycoprotein function in rats.
Journal of chemotherapy (Florence, Italy) 20080601
-
Functional evaluation of polymorphisms in the human ABCB1 gene and the impact on clinical responses of antiepileptic drugs.
Pharmacogenetics and genomics 20080501
-
Chitosan-N-acetyl cysteine conjugates: in vitro evaluation of permeation enhancing and P-glycoprotein inhibiting properties.
Drug delivery 20080501
-
Reversal effect of isotetrandrine, an isoquinoline alkaloid extracted from Caulis Mahoniae, on P-glycoprotein-mediated doxorubicin-resistance in human breast cancer (MCF-7/DOX) cells.
Yao xue xue bao = Acta pharmaceutica Sinica 20080501
-
Nitric oxide down-regulates the expression of organic cation transporters (OCT) 1 and 2 in rat kidney during endotoxemia.
European journal of pharmacology 20080428
-
Histone deacetylase inhibitor apicidin-mediated drug resistance: involvement of P-glycoprotein.
Biochemical and biophysical research communications 20080418
-
Reversal effect of a macrocyclic bisbibenzyl plagiochin E on multidrug resistance in adriamycin-resistant K562/A02 cells.
European journal of pharmacology 20080414
-
Increased P-glycoprotein function and level after long-term exposure of four antiepileptic drugs to rat brain microvascular endothelial cells in vitro.
Neuroscience letters 20080404
-
Casiopeína IIgly induced cytotoxicity to HeLa cells depletes the levels of reduced glutathione and is prevented by dimethyl sulfoxide.
Toxicology in vitro : an international journal published in association with BIBRA 20080401
-
Plasmodium falciparum: erythrocytic stages die by autophagic-like cell death under drug pressure.
Experimental parasitology 20080401
-
[Effect of Tween-80 on the permeability of rhodamine 123, a P-gp substrate across rat intestinal membranes in vitro].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080401
-
Inhibition of P-glycoprotein (ABCB1)- and multidrug resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1((R)).
Biochemical pharmacology 20080315
-
Inhibitory effect of docosahexaenoic acid (DHA) on the intestinal metabolism of midazolam: in vitro and in vivo studies in rats.
International journal of pharmaceutics 20080303
-
Microcystin-RR induced apoptosis in tobacco BY-2 suspension cells is mediated by reactive oxygen species and mitochondrial permeability transition pore status.
Toxicology in vitro : an international journal published in association with BIBRA 20080301
-
Plagiochin E, a botanic-derived phenolic compound, reverses fungal resistance to fluconazole relating to the efflux pump.
Journal of applied microbiology 20080301
-
Polychlorinated biphenyl-induced oxidative stress in organotypic co-cultures: experimental dopamine depletion prevents reductions in GABA.
Neurotoxicology 20080301
-
Inhibition of multidrug resistance by adamantylgb3, a globotriaosylceramide analog.
The Journal of biological chemistry 20080222
-
Anti-Trypanosoma cruzi effects of cyclosporin A derivatives: possible role of a P-glycoprotein and parasite cyclophilins.
Parasitology 20080201
-
A comparative evaluation of corneal epithelial cell cultures for assessing ocular permeability.
Alternatives to laboratory animals : ATLA 20080201
-
Selective toxicity of ginsenoside Rg3 on multidrug resistant cells by membrane fluidity modulation.
Archives of pharmacal research 20080201
-
Interactions of attention-deficit/hyperactivity disorder therapeutic agents with the efflux transporter P-glycoprotein.
European journal of pharmacology 20080114
-
Biochemical study of idebenone effect on mitochondrial metabolism of yeast.
Cell biology international 20080101
-
Activity of drug efflux transporters in tumor cells under hypoxic conditions.
Advances in experimental medicine and biology 20080101
-
Role of P-glycoprotein in evolution of populations of chronic myeloid leukemia cells treated with imatinib.
Biochemistry. Biokhimiia 20080101
-
A new procedure for the quantitative assessment of p-glycoprotein efflux pump associated with human T lymphocytes.
Ethnicity & disease 20080101
-
Effects of monoglycerides on P-glycoprotein: modulation of the activity and expression in Caco-2 cell monolayers.
Molecular pharmaceutics 20080101
-
Effects of monoglycerides on rhodamine 123 accumulation, estradiol 17 beta-D-glucuronide bidirectional transport and MRP2 protein expression within Caco-2 cells.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20080101
-
Assessment of ileal epithelial P-glycoprotein dysfunction induced by ischemia/reperfusion using in vivo animal model.
Drug metabolism and pharmacokinetics 20080101
-
Antitumour properties of acridone alkaloids on a murine lymphoma cell line.
Anticancer research 20080101
-
New functional assay of P-glycoprotein activity using Hoechst 33342.
Bioorganic & medicinal chemistry 20071201
-
Substituted tetrahydroisoquinoline compound B3 inhibited P-glycoprotein-mediated multidrug resistance in-vitro and in-vivo.
The Journal of pharmacy and pharmacology 20071201
-
In-vivo and in-vitro studies on the effect of Huang-Lian-Jie-Du-Tang on nimodipine transport across rat blood-brain barrier.
The Journal of pharmacy and pharmacology 20071201
-
[Interaction between (E)-2-(4-(diethylamino methyl) benzylidene)-5,6-dimethoxy-2,3-dihydroinden-one and P-glycoprotein].
Yao xue xue bao = Acta pharmaceutica Sinica 20071201
-
Biocompatibility of contact lens solutions using confocal laser scanning microscopy and the in vitro bovine cornea.
Eye & contact lens 20071101
-
ZD6474 reverses multidrug resistance by directly inhibiting the function of P-glycoprotein.
British journal of cancer 20071008
-
The effect of ABCB1 polymorphism on the pharmacokinetics of saquinavir alone and in combination with ritonavir.
Clinical pharmacology and therapeutics 20071001
-
Plasma LDL cholesterol has no impact on P-glycoprotein (MDR1/ABCB1) activity in human peripheral blood mononuclear cells.
Naunyn-Schmiedeberg's archives of pharmacology 20071001
-
Increased P-glycoprotein expression and decreased phenobarbital distribution in the brain of pentylenetetrazole-kindled rats.
Neuropharmacology 20071001
-
The characteristics of Hep-2 cell with multiple drug resistance induced by Taxol.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20071001
-
Assessment of antiepileptic drugs as substrates for canine P-glycoprotein.
American journal of veterinary research 20071001
-
Effects of capsaicin on cellular damage and monolayer permeability in human intestinal Caco-2 cells.
Biological & pharmaceutical bulletin 20071001
-
Targeting the central nervous system: in vivo experiments with peptide-derivatized nanoparticles loaded with Loperamide and Rhodamine-123.
Journal of controlled release : official journal of the Controlled Release Society 20070911
-
Effects of diosmin, a flavonoid glycoside in citrus fruits, on P-glycoprotein-mediated drug efflux in human intestinal Caco-2 cells.
Journal of agricultural and food chemistry 20070905
-
Effect of cell differentiation and passage number on the expression of efflux proteins in wild type and vinblastine-induced Caco-2 cell lines.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070901
-
Effects of benzo(e)pyrene and benzo(a)pyrene on P-glycoprotein-mediated transport in Caco-2 cell monolayer: a comparative approach.
Toxicology in vitro : an international journal published in association with BIBRA 20070801
-
Decreased intestinal CYP3A and P-glycoprotein activities in rats with adjuvant arthritis.
Drug metabolism and pharmacokinetics 20070801
-
Adaptive response to increased bile acids: induction of MDR1 gene expression and P-glycoprotein activity in renal epithelial cells.
Pflugers Archiv : European journal of physiology 20070701
-
Mitochondrial inner membrane electrophysiology assessed by rhodamine-123 transport and fluorescence.
Annals of biomedical engineering 20070701
-
Remodelling of the SUR-Kir6.2 interface of the KATP channel upon ATP binding revealed by the conformational blocker rhodamine 123.
The Journal of physiology 20070701
-
Effects of Labrasol and other pharmaceutical excipients on the intestinal transport and absorption of rhodamine123, a P-glycoprotein substrate, in rats.
Biological & pharmaceutical bulletin 20070701
-
Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of P-glycoprotein.
Molecular cancer therapeutics 20070701
-
Inhibition of P-glycoprotein function by tannic acid and pentagalloylglucose.
The Journal of pharmacy and pharmacology 20070701
-
CJY, an isoflavone, reverses P-glycoprotein-mediated multidrug-resistance in doxorubicin-resistant human myelogenous leukaemia (K562/DOX) cells.
The Journal of pharmacy and pharmacology 20070701
-
Delayed mitochondrial dysfunction in apoptotic hair cells in chinchilla cochleae following exposure to impulse noise.
Apoptosis : an international journal on programmed cell death 20070601
-
Stereoselective regulation of MDR1 expression in Caco-2 cells by cetirizine enantiomers.
Chirality 20070601
-
Role of hypoxia-inducible factor-alpha in hepatitis-B-virus X protein-mediated MDR1 activation.
Biochemical and biophysical research communications 20070601
-
Is steroid resistance related to multidrug resistance-I (MDR-I) in rheumatoid arthritis?
International immunopharmacology 20070601
-
Comparison of the inhibitory activity of anti-HIV drugs on P-glycoprotein.
Biochemical pharmacology 20070515
-
Differential subcellular distribution of mitoxantrone in relation to chemosensitization in two human breast cancer cell lines.
Drug metabolism and disposition: the biological fate of chemicals 20070501
-
An inhibitory role of nitric oxide in the dynamic regulation of the blood-brain barrier function.
Cellular and molecular neurobiology 20070501
-
SLIM: a new method for molecular imaging.
Microscopy research and technique 20070501
-
Ethanol induced mitochondria injury and permeability transition pore opening: role of mitochondria in alcoholic liver disease.
World journal of gastroenterology 20070428
-
Withanolide induces apoptosis in HL-60 leukemia cells via mitochondria mediated cytochrome c release and caspase activation.
Chemico-biological interactions 20070405
-
Risperidone and paliperidone inhibit p-glycoprotein activity in vitro.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070401
-
P-glycoprotein (MDR1) functional activity in human alveolar epithelial cell monolayers.
Cell and tissue research 20070401
-
Morphological and functional changes in p-glycoprotein during dexamethasone-induced hepatomegaly.
Clinical and experimental pharmacology & physiology 20070401
-
Parallel separation of multiple samples with negative pressure sample injection on a 3-D microfluidic array chip.
Electrophoresis 20070401
-
Detection and functional characterization of Pgp1 (ABCB1) and MRP3 (ABCC3) efflux transporters in the PLHC-1 fish hepatoma cell line.
Aquatic toxicology (Amsterdam, Netherlands) 20070330
-
Characterization of WIF-B9/R cells as an in vitro model with hepatocyte-like polarity and enhanced expression of canalicular ABC transporters involved in phase III of hepatic detoxification.
Toxicology 20070322
-
Dialysis of boar semen prior to freezing-thawing: its effects on post-thaw sperm characteristics.
Theriogenology 20070315
-
Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts.
Leukemia 20070301
-
New noncellular fluorescence microplate screening assay for scavenging activity against singlet oxygen.
Analytical and bioanalytical chemistry 20070301
-
High-molecular-weight polyphenols from oolong tea and black tea: purification, some properties, and role in increasing mitochondrial membrane potential.
Bioscience, biotechnology, and biochemistry 20070301
-
Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin.
Molecular and cellular biochemistry 20070201
-
Air-liquid interface (ALI) culture of human bronchial epithelial cell monolayers as an in vitro model for airway drug transport studies.
Journal of pharmaceutical sciences 20070201
-
Expression of the MDR1 gene and P-glycoprotein in canine mast cell tumor cell lines.
The Journal of veterinary medical science 20070201
-
A 'silent' polymorphism in the MDR1 gene changes substrate specificity.
Science (New York, N.Y.) 20070126
-
Effects of Kaempferia parviflora extracts and their flavone constituents on P-glycoprotein function.
Journal of pharmaceutical sciences 20070101
-
Cobalamin potentiates vinblastine cytotoxicity through downregulation of mdr-1 gene expression in HepG2 cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101
-
Assay for apoptosis using the mitochondrial probes, Rhodamine123 and 10-N-nonyl acridine orange.
Nature protocols 20070101
-
Field amplified sample stacking coupled with chip-based capillary electrophoresis using negative pressure sample injection technique.
Journal of chromatography. A 20061229
-
A novel MDR1 G1199T variant alters drug resistance and efflux transport activity of P-glycoprotein in recombinant Hek cells.
Journal of pharmaceutical sciences 20061201
-
In vivo comparison of various polymeric and low molecular mass inhibitors of intestinal P-glycoprotein.
Biomaterials 20061201
-
Down-regulation of ABCB1 transporter by atorvastatin in a human hepatoma cell line and in human peripheral blood mononuclear cells.
Biochimica et biophysica acta 20061201
-
The role of Leishmania enriettii multidrug resistance protein 1 (LeMDR1) in mediating drug resistance is iron-dependent.
Molecular and biochemical parasitology 20061201
-
Down-regulation of P-glycoprotein expression in MDR breast cancer cell MCF-7/ADR by honokiol.
Cancer letters 20061118
-
Development and characterization of multidrug resistant human hepatocarcinoma cell line in nude mice.
World journal of gastroenterology 20061107
-
Rhodamine 123 permeability through the catfish intestinal wall: Relationship to thermal acclimation and acute temperature change.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20061101
-
Concomitant real-time monitoring of intracellular reactive oxygen species and mitochondrial membrane potential in individual living promonocytic cells.
Journal of immunological methods 20061020
-
A kinetic study of Rhodamine123 pumping by P-glycoprotein.
Biochimica et biophysica acta 20061001
-
Improvement of intestinal absorption of P-glycoprotein substrate by D-tartaric acid.
Drug metabolism and pharmacokinetics 20061001
-
Gomisin A alters substrate interaction and reverses P-glycoprotein-mediated multidrug resistance in HepG2-DR cells.
Biochemical pharmacology 20060928
-
Bivalent probes of the human multidrug transporter P-glycoprotein.
Biochemistry 20060926
-
Indomethacin overcomes doxorubicin resistance with inhibiting multi-drug resistance protein 1 (MRP1).
Cancer chemotherapy and pharmacology 20060901
-
Evaluation of antipsychotic drugs as inhibitors of multidrug resistance transporter P-glycoprotein.
Psychopharmacology 20060901
-
Up-regulation of P-glycoprotein expression by glutathione depletion-induced oxidative stress in rat brain microvessel endothelial cells.
Journal of neurochemistry 20060901
-
In vivo evaluation of an oral delivery system for P-gp substrates based on thiolated chitosan.
Biomaterials 20060801
-
Visceral leishmaniasis, or kala azar (KA): high incidence of refractoriness to antimony is contributed by anthroponotic transmission via post-KA dermal leishmaniasis.
The Journal of infectious diseases 20060801
-
[Determination of rhodamine 123 in cell lysate by high-performance liquid chromatography with visible wavelength detection].
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20060801
-
Hyperspectral imaging system using acousto-optic tunable filter for flow cytometry applications.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060801
-
The alpha-subunit of Leishmania F1 ATP synthase hydrolyzes ATP in presence of tRNA.
The Journal of biological chemistry 20060714
-
Apparent active transport of MDMA is not mediated by P-glycoprotein: a comparison with MDCK and Caco-2 monolayers.
Biopharmaceutics & drug disposition 20060701
-
Effect of benzo[a]pyrene on P-glycoprotein-mediated transport in Caco-2 cell monolayer.
Toxicology 20060601
-
Ischemia/reperfusion injury in the monolayers of human intestinal epithelial cell line caco-2 and its recovery by antioxidants.
Drug metabolism and pharmacokinetics 20060601
-
Thalidomide does not interact with P-glycoprotein.
Cancer chemotherapy and pharmacology 20060501
-
JC-1, a sensitive probe for a simultaneous detection of P-glycoprotein activity and apoptosis in leukemic cells.
Cytometry. Part B, Clinical cytometry 20060501
-
Modulation of intestinal P-glycoprotein function by polyethylene glycols and their derivatives by in vitro transport and in situ absorption studies.
International journal of pharmaceutics 20060426
-
CJZ3, a lomerizine derivative, modulates P-glycoprotein function in rat brain microvessel endothelial cells.
Acta pharmacologica Sinica 20060401
-
Glutathione and thiolated chitosan inhibit multidrug resistance P-glycoprotein activity in excised small intestine.
Journal of controlled release : official journal of the Controlled Release Society 20060310
-
Influence of vitamin E TPGS poly(ethylene glycol) chain length on apical efflux transporters in Caco-2 cell monolayers.
Journal of controlled release : official journal of the Controlled Release Society 20060310
-
Somatostatin inhibits oxidative respiration in pancreatic beta-cells.
Endocrinology 20060301
-
Carbonyl stress and NMDA receptor activation contribute to methylglyoxal neurotoxicity.
Free radical biology & medicine 20060301
-
In vivo and in vitro modulation of MDR molecules in murine thymocytes.
International immunopharmacology 20060201
-
Development of an on-line extraction turbulent flow chromatography tandem mass spectrometry method for cassette analysis of Caco-2 cell based bi-directional assay samples.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060118
-
Improved synthesis and in vitro characterization of chitosan-thioethylamidine conjugate.
Biomaterials 20060101
-
Transport of glyburide by placental ABC transporters: implications in fetal drug exposure.
Placenta 20060101
-
Verapamil induces upregulation of P-glycoprotein expression on human monocyte derived dendritic cells.
Immunological investigations 20060101
-
Alteration of genomic responses to doxorubicin and prevention of MDR in breast cancer cells by a polymer excipient: pluronic P85.
Molecular pharmaceutics 20060101
-
Interaction between doxorubicin and the resistance modifier stilbene on multidrug resistant mouse lymphoma and human breast cancer cells.
Anticancer research 20060101
-
Involvement of oxidative stress response genes in redox homeostasis, the level of reactive oxygen species, and ageing in Saccharomyces cerevisiae.
FEMS yeast research 20051201
-
Photodynamic damages induced by a monocationic porphyrin derivative in a human carcinoma cell line.
The international journal of biochemistry & cell biology 20051201
-
Effect of a beta-lapachone-derived naphthoimidazole on Trypanosoma cruzi: identification of target organelles.
The Journal of antimicrobial chemotherapy 20051201
-
Simultaneous determination of glutathione and reactive oxygen species in individual cells by microchip electrophoresis.
Electrophoresis 20051201
-
Structure-activity relationships of the inhibitory effects of flavonoids on P-glycoprotein-mediated transport in KB-C2 cells.
Biological & pharmaceutical bulletin 20051201
-
Prediction of absorbability of poorly water-soluble drugs based on permeability obtained through modified in vitro chamber method.
Drug metabolism and pharmacokinetics 20051201
-
Acute glutathione depletion restricts mitochondrial ATP export in cerebellar granule neurons.
The Journal of biological chemistry 20051118
-
Cellular organisation in meiotic and early post-meiotic rice anthers.
Cell biology international 20051101
-
Canine mdr1 gene mutation in Japan.
The Journal of veterinary medical science 20051101
-
Ultrafast dynamics in a nanocage of enzymes: solvation and fluorescence resonance energy transfer in reverse micelles.
Journal of colloid and interface science 20051015
-
Metabolic dysfunction during neuronal activation in the ex vivo hippocampus from chronic epileptic rats and humans.
Brain : a journal of neurology 20051001
-
Transport characteristics of rutin deca (H-) sulfonate sodium across Caco-2 cell monolayers.
The Journal of pharmacy and pharmacology 20051001
-
Reversal of p-glycoprotein-mediated multidrug resistance by CJX1, an amlodipine derivative, in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells.
Life sciences 20050916
-
Gefitinib, an EGFR tyrosine kinase inhibitor, directly inhibits the function of P-glycoprotein in multidrug resistant cancer cells.
Lung cancer (Amsterdam, Netherlands) 20050901
-
Glutathione depletion renders rat hepatocytes sensitive to nitric oxide donor-mediated toxicity.
Hepatology (Baltimore, Md.) 20050901
-
Glucose-dependent changes in NAD(P)H-related fluorescence lifetime of adipocytes and fibroblasts in vitro: potential for non-invasive glucose sensing in diabetes mellitus.
Journal of photochemistry and photobiology. B, Biology 20050801
-
Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR.
Acta pharmacologica Sinica 20050801
-
Functional analysis of human hematopoietic stem cell gene expression using zebrafish.
PLoS biology 20050801
-
Preparation of nanoparticles composed of poly(gamma-glutamic acid)-poly(lactide) block copolymers and evaluation of their uptake by HepG2 cells.
Journal of controlled release : official journal of the Controlled Release Society 20050720
-
Change in mitochondrial membrane potential is the key mechanism in early warm hepatic ischemia-reperfusion injury.
Microvascular research 20050701
-
Identification of a multixenobiotic resistance mechanism in primary cultured epidermal cells from Oncorhynchus mykiss and the effects of environmental complex mixtures on its activity.
Aquatic toxicology (Amsterdam, Netherlands) 20050615
-
Biphasic accumulation kinetics of [99mTc]-hexakis-2-methoxyisobutyl isonitrile in tumour cells and its modulation by lipophilic P-glycoprotein ligands.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050601
-
Ultraviolet damages sperm mitochondrial function and membrane integrity in the sea urchin Anthocidaris crassispina.
Ecotoxicology and environmental safety 20050501
-
Lamellarin D: a novel pro-apoptotic agent from marine origin insensitive to P-glycoprotein-mediated drug efflux.
Cancer letters 20050428
-
Zinc-induced anti-apoptotic effects in SH-SY5Y neuroblastoma cells via the extracellular signal-regulated kinase 1/2.
Brain research. Molecular brain research 20050427
-
A downstream role for protein kinase Calpha in the cytosolic phospholipase A2-dependent protective signalling mediated by peroxynitrite in U937 cells.
Biochemical pharmacology 20050415
-
Simultaneous release of hydrophobic and cationic solutes from thin-film 'plum-pudding' gels: a multifunctional platform for surface drug delivery?
The journal of physical chemistry. B 20050407
-
Effects of miltefosine on membrane permeability and accumulation of [99mTc]-hexakis-2-methoxyisobutyl isonitrile, 2-[18F]fluoro-2-deoxy-D-glucose, daunorubucin and rhodamine123 in multidrug-resistant and sensitive cells.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050401
-
Expression and activity of multidrug resistance protein 1 in a murine thymoma cell line.
Immunology 20050401
-
Regional difference in P-glycoprotein function in rat intestine.
Drug metabolism and pharmacokinetics 20050401
-
Difference in propagation of Ca2+ release in atrial and ventricular myocytes.
The Japanese journal of physiology 20050401
-
Brain pericytes contribute to the induction and up-regulation of blood-brain barrier functions through transforming growth factor-beta production.
Brain research 20050321
-
Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes.
Drug metabolism and disposition: the biological fate of chemicals 20050301
-
Effects of dietary chemopreventive phytochemicals on P-glycoprotein function.
Biochemical and biophysical research communications 20050218
-
Optical assessment of motoneuron function in a 'twenty-four-hour' acute spinal cord slice model from fetal rats.
Journal of neuroscience methods 20050215
-
Chemical modification of paclitaxel (Taxol) reduces P-glycoprotein interactions and increases permeation across the blood-brain barrier in vitro and in situ.
Journal of medicinal chemistry 20050210
-
Modulation of P-glycoprotein function by amlodipine derivatives in brain microvessel endothelial cells of rats.
Acta pharmacologica Sinica 20050201
-
Single amino acid (482) variants of the ABCG2 multidrug transporter: major differences in transport capacity and substrate recognition.
Biochimica et biophysica acta 20050201
-
Inhibition of P-glycoprotein function and expression by kaempferol and quercetin.
Journal of chemotherapy (Florence, Italy) 20050201
-
A comparison of hepatocyte cytotoxic mechanisms for chromate and arsenite.
Toxicology 20050131
-
Determination of Rhodamine 123 in cell lysate by HPLC with visible wavelength detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050125
-
Interaction of LDS-751 with P-glycoprotein and mapping of the location of the R drug binding site.
Biochemistry 20050118
-
Cultured gill epithelial cells from tilapia (Oreochromis niloticus): a new in vitro assay for toxicants.
Aquatic toxicology (Amsterdam, Netherlands) 20050118
-
Arginine-482 is not essential for transport of antibiotics, primary bile acids and unconjugated sterols by the human breast cancer resistance protein (ABCG2).
The Biochemical journal 20050115
-
Impact of the cyclooxygenase system on doxorubicin-induced functional multidrug resistance 1 overexpression and doxorubicin sensitivity in acute myeloid leukemic HL-60 cells.
The Journal of pharmacology and experimental therapeutics 20050101
-
Cytoplasmic and mitochondrial Ca levels in brown adipocytes.
Acta physiologica Scandinavica 20050101
-
Comparative study on the effects of cyclosporin a in renal cells in culture.
Nephron. Experimental nephrology 20050101
-
Antileukemic activity and cellular metabolism of the aryl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07).
Arzneimittel-Forschung 20050101
-
A comparison of the sensitivity of photodamage assays in rat basophilic leukemia cells.
Photochemistry and photobiology 20050101
-
Effects of selected flavonoids and carotenoids on drug accumulation and apoptosis induction in multidrug-resistant colon cancer cells expressing MDR1/LRP.
In vivo (Athens, Greece) 20050101
-
[Changes in the distribution of mitochondria in mouse embryos blocked at the two-cell stage].
Ontogenez 20050101
-
Human sarcoma cell lines MES-SA and MES-SA/Dx5 as a model for multidrug resistance modulators screening.
Anticancer research 20050101
-
Flow cytometric monitoring of fluorescent drug retention and efflux.
Methods in molecular medicine 20050101
-
Reduced mitochondrial membrane potential and metabolism correspond to acute chloroform toxicity of in vitro hepatocytes.
Journal of applied toxicology : JAT 20050101
-
Photophysical, photochemical, and tumor-selectivity properties of bromine derivatives of rhodamine-123.
Photochemistry and photobiology 20050101
-
Effect of the modulation of the membrane lipid composition on the localization and function of P-glycoprotein in MDR1-MDCK cells.
In vitro cellular & developmental biology. Animal 20050101
-
The effects of jatrophane derivatives on the reversion of MDR1- and MRP-mediated multidrug resistance in the MDA-MB-231 (HTB-26) cell line.
Anticancer research 20050101
-
Mitochondrial dysfunction in mouse oocytes results in preimplantation embryo arrest in vitro.
Biology of reproduction 20041201
-
Mitochondrial metabolism reveals a functional architecture in intact islets of Langerhans from normal and diabetic Psammomys obesus.
American journal of physiology. Endocrinology and metabolism 20041201
-
Effect of p-glycoprotein inhibitor combinations on drug efflux from rat brain microvessel endothelial cells.
Die Pharmazie 20041201
-
Nitric oxide mediates cyclosporine-induced impairment of the blood-brain barrier in cocultures of mouse brain endothelial cells and rat astrocytes.
European journal of pharmacology 20041128
-
Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder.
Biochemical pharmacology 20041115
-
Inhibitory effect of a bitter melon extract on the P-glycoprotein activity in intestinal Caco-2 cells.
British journal of pharmacology 20041001
-
Effect of rabeprazole on MDR1-mediated transport of Rhodamine 123 in Caco-2 and Hvr100-6 cells.
Biological & pharmaceutical bulletin 20041001
-
Comparison of metabolic oscillations from mouse pancreatic beta cells and islets.
Endocrine 20041001
-
Arginine482 to threonine mutation in the breast cancer resistance protein ABCG2 inhibits rhodamine 123 transport while increasing binding.
The Biochemical journal 20040901
-
Possible harmful effects on central nervous system cells in the use of physiological saline as an irrigant during neurosurgical procedures.
Surgical neurology 20040801
-
Evidence for modulation of P-glycoprotein-mediated efflux by methoxypolyethylene glycol-block-Polycaprolactone amphiphilic diblock copolymers.
Pharmaceutical research 20040801
-
Isolation and characterization of the mitochondrion-like organelle from Blastocystis hominis.
Journal of microbiological methods 20040701
-
Apoptotic-like mitochondrial events associated to phosphatidylserine exposure in blood platelets induced by local anaesthetics.
Thrombosis and haemostasis 20040701
-
Insulin feedback alters mitochondrial activity through an ATP-sensitive K+ channel-dependent pathway in mouse islets and beta-cells.
Diabetes 20040701
-
Molecular cytotoxic mechanisms of anticancer hydroxychalcones.
Chemico-biological interactions 20040630
-
Avermectins inhibit multidrug resistance of tumor cells.
European journal of pharmacology 20040616
-
ABC transporter activities of murine hematopoietic stem cells vary according to their developmental and activation status.
Blood 20040615
-
Reversal of multidrug resistance in drug-resistant human gastric cancer cell line SGC7901/VCR by antiprogestin drug mifepristone.
World journal of gastroenterology 20040615
-
Evaluation and comparison of MRP1 activity with three fluorescent dyes and three modulators in leukemic cell lines.
Leukemia research 20040601
-
Flow cytometric measurement of neutrophil respiratory burst in whole bovine blood using live Staphylococcus aureus.
Journal of immunological methods 20040601
-
Oligonucleotides blocking glucosylceramide synthase expression selectively reverse drug resistance in cancer cells.
Journal of lipid research 20040501
-
Fexofenadine does not affect omeprazole pharmacokinetics: both are putative P-glycoprotein substrates.
Basic & clinical pharmacology & toxicology 20040501
-
Cellular features of an apoptotic form of programmed cell death during the development of the ascidian, Boltenia villosa.
Zoological science 20040501
-
[Reversal of multidrug resistance by lomerizine in K562/ADM cells].
Yao xue xue bao = Acta pharmaceutica Sinica 20040501
-
Cholesterol modulates P-glycoprotein activity in human peripheral blood mononuclear cells.
Biochemical and biophysical research communications 20040409
-
Modulation of intestinal P-glycoprotein function by cremophor EL and other surfactants by an in vitro diffusion chamber method using the isolated rat intestinal membranes.
Journal of pharmaceutical sciences 20040401
-
Effect of heat preconditioning on the uptake and permeability of R123 in brain microvessel endothelial cells during mild heat treatment.
Journal of pharmaceutical sciences 20040401
-
Implication of mitochondrial involvement in apoptotic activity of fragile histidine triad gene: application of synchronous luminescence spectroscopy.
Biopolymers 20040301
-
Localization and activity of multidrug resistance protein 1 in the secretory pathway of Leishmania parasites.
Molecular microbiology 20040301
-
Mitochondrial polarisation status and [Ca2+]i signalling in rat cerebellar granule neurones aged in vitro.
Neurobiology of aging 20040301
-
Cadmium-induced mitochondrial membrane-potential dissipation does not necessarily require cytosolic oxidative stress: studies using rhodamine-123 fluorescence unquenching.
Toxicological sciences : an official journal of the Society of Toxicology 20040201
-
In vitro effect of manganese chloride exposure on reactive oxygen species generation and respiratory chain complexes activities of mitochondria isolated from rat brain.
Toxicology in vitro : an international journal published in association with BIBRA 20040201
-
UV dose-dependent caspase activation in a corneal epithelial cell line.
Current eye research 20040201
-
Morphine prevents glutamate-induced death of primary rat neonatal astrocytes through modulation of intracellular redox.
Immunopharmacology and immunotoxicology 20040201
-
Flow cytometry of apoptosis.
Current protocols in cell biology 20040201
-
The modulation of action potential generation by calcium-induced calcium release is enhanced by mitochondrial inhibitors in mudpuppy parasympathetic neurons.
Neuroscience 20040101
-
Mitochondria in tumor cells studied by laser scanning confocal microscopy.
Journal of biomedical optics 20040101
-
Modulation of multidrug resistance and apoptosis of cancer cells by selected carotenoids.
In vivo (Athens, Greece) 20040101
-
New silicon compounds as resistance modifiers against multidrug-resistant cancer cells.
Anticancer research 20040101
-
Inhibition of P-glycoprotein transport: a mechanism for endocrine disruption in the channel catfish?
Marine environmental research 20040101
-
Increasing of oxidative stress from mitochondria in type 2 diabetic patients.
Diabetes/metabolism research and reviews 20040101
-
Functional characterization of human breast cancer resistance protein (BCRP, ABCG2) expressed in the oocytes of Xenopus laevis.
Molecular pharmacology 20031201
-
Epifluorescence microscope methods for bacterial enumeration in a 4-chlorophenol degrading consortium.
Biotechnology letters 20031201
-
Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood-brain barrier model for drug uptake and transport studies.
Brain research 20031114
-
Interaction of imatinib mesilate with human P-glycoprotein.
The Journal of pharmacology and experimental therapeutics 20031101
-
Spontaneous changes in mitochondrial membrane potential in single isolated brain mitochondria.
Biophysical journal 20031101
-
Cytokines alter the expression and activity of the multidrug resistance transporters in human hepatoma cell lines; analysis using RT-PCR and cDNA microarrays.
Journal of pharmaceutical sciences 20031101
-
Effect of E6, a novel calmodulin inhibitor, on activity of P-glycoprotein in purified primary cultured rat brain microvessel endothelial cells.
Acta pharmacologica Sinica 20031101
-
The expression of P-glycoprotein does influence the distribution of novel fluorescent compounds in solid tumour models.
British journal of cancer 20031020
-
Mechanism of granulosa cell death during follicular atresia depends on follicular size.
Theriogenology 20031001
-
P-glycoprotein and multidrug resistance-associated protein mediate specific patterns of multidrug resistance in malignant glioma cell lines, but not in primary glioma cells.
Brain pathology (Zurich, Switzerland) 20031001
-
Rhodamine 123 as a probe of mitochondrial membrane potential: evaluation of proton flux through F(0) during ATP synthesis.
Biochimica et biophysica acta 20030930
-
P-glycoprotein-like protein contributes to cadmium resistance in Euglena gracilis.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20030901
-
Kinetic analysis of rhodamines efflux mediated by the multidrug resistance protein (MRP1).
Biophysical journal 20030901
-
Quinine as a multidrug resistance inhibitor: a phase 3 multicentric randomized study in adult de novo acute myelogenous leukemia.
Blood 20030815
-
Enhancement of sensitivity to cisplatin by orobol is associated with increased mitochondrial cytochrome c release in human ovarian carcinoma cells.
Gynecologic oncology 20030801
-
MDR1 polymorphisms G2677T in exon 21 and C3435T in exon 26 fail to affect rhodamine 123 efflux in peripheral blood lymphocytes.
Fundamental & clinical pharmacology 20030801
-
Rapid assessment of P-glycoprotein inhibition and induction in vitro.
Pharmaceutical research 20030801
-
Rhodamine 123 requires carrier-mediated influx for its activity as a P-glycoprotein substrate in Caco-2 cells.
Pharmaceutical research 20030801
-
Efflux ratio cannot assess P-glycoprotein-mediated attenuation of absorptive transport: asymmetric effect of P-glycoprotein on absorptive and secretory transport across Caco-2 cell monolayers.
Pharmaceutical research 20030801
-
Mitotracker green is a P-glycoprotein substrate.
Bioscience reports 20030801
-
Molecular evidence and functional expression of P-glycoprotein (MDR1) in human and rabbit cornea and corneal epithelial cell lines.
Investigative ophthalmology & visual science 20030701
-
Sterol transport by the human breast cancer resistance protein (ABCG2) expressed in Lactococcus lactis.
The Journal of biological chemistry 20030606
-
Examination of the functional activity of P-glycoprotein in the rat placental barrier using rhodamine 123.
The Journal of pharmacology and experimental therapeutics 20030601
-
Modulation of P-glycoprotein-mediated multidrug resistance by flavonoid derivatives and analogues.
Journal of medicinal chemistry 20030522
-
Lopinavir: acute exposure inhibits P-glycoprotein; extended exposure induces P-glycoprotein.
AIDS (London, England) 20030502
-
Mechanisms of ocular toxicity using the in vitro bovine lens and sodium dodecyl sulfate as a chemical model.
Toxicological sciences : an official journal of the Society of Toxicology 20030501
-
The multidrug resistance protein ABCC1 drug-binding domains show selective sensitivity to mild detergents.
Biochemical and biophysical research communications 20030418
-
Optimisation of cell-based assays for medium throughput screening of oxidative stress.
Toxicology in vitro : an international journal published in association with BIBRA 20030401
-
Age-related changes of P-glycoprotein-mediated rhodamine 123 efflux in normal human bone marrow hematopoietic stem cells.
Leukemia 20030401
-
Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites.
Pharmaceutical research 20030401
-
CPT-11-induced cell death in leukemic cells is not affected by the MDR phenotype.
Leukemia research 20030301
-
Effects of a series of dihydroanthracene derivatives on drug efflux in multidrug resistant cancer cells.
European journal of medicinal chemistry 20030301
-
Reversal of P-glycoprotein-mediated multidrug resistance by ginsenoside Rg(3).
Biochemical pharmacology 20030101
-
Synthesis of aza mono, bi and tricyclic compounds. Evaluation of their anti MDR activity.
European journal of medicinal chemistry 20030101
-
Decrease of intestinal P-glycoprotein activity by 2n-propylquinoline, a new oral treatment for visceral leishmaniasis.
Experimental parasitology 20030101
-
Tamoxifen, protein kinase C and rat sperm mitochondria.
Cell biology international 20030101
-
Overcoming the blood-brain barrier to taxane delivery for neurodegenerative diseases and brain tumors.
Journal of molecular neuroscience : MN 20030101
-
Non-invasive glucose monitoring by NAD(P)H autofluorescence spectroscopy in fibroblasts and adipocytes: a model for skin glucose sensing.
Diabetes technology & therapeutics 20030101
-
Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis).
Journal of medicinal chemistry 20021219
-
Changes in mitochondrial status associated with altered Ca2+ homeostasis in aged cerebellar granule neurons in brain slices.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20021215
-
Effects of P-glycoprotein inhibitors on cadmium accumulation in cultured renal epithelial cells, LLC-PK1, and OK.
Toxicology and applied pharmacology 20021215
-
Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation.
The Journal of biological chemistry 20021213
-
The spleen is a major site of megakaryopoiesis following transplantation of murine hematopoietic stem cells.
Blood 20021201
-
Effect of zolpidem on human cytochrome P450 activity, and on transport mediated by P-glycoprotein.
Biopharmaceutics & drug disposition 20021201
-
Hyperresistance to photosensitized lipid peroxidation and apoptotic killing in 5-aminolevulinate-treated tumor cells overexpressing mitochondrial GPX4.
Free radical biology & medicine 20021115
-
Properties of a fetal multipotent neural stem cell (NEP cell).
Developmental biology 20021115
-
Evaluation of cell viability by double-staining fluorescence assay.
Gan to kagaku ryoho. Cancer & chemotherapy 20021101
-
Differential regulation of doxorubicin-induced mitochondrial dysfunction and apoptosis by Bcl-2 in mammary adenocarcinoma (MTLn3) cells.
The Journal of biological chemistry 20020927
-
Elevation of P-glycoprotein function by a catechin in green tea.
Biochemical and biophysical research communications 20020920
-
Effects of nonionic surfactants on membrane transporters in Caco-2 cell monolayers.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020901
-
Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells.
Biochemical pharmacology 20020815
-
Effect of interleukin-2 on intestinal P-glycoprotein expression and functionality in mice.
The Journal of pharmacology and experimental therapeutics 20020801
-
Liver and marrow of adult mdr-1a/1b(-/-) mice show normal generation, function, and multi-tissue trafficking of primitive hematopoietic cells.
Experimental hematology 20020801
-
Effect of hr-IL2 treatment on intestinal P-glycoprotein expression and activity in Caco-2 cells.
The Journal of pharmacy and pharmacology 20020801
-
Reversal of P-glycoprotein-mediated multidrug resistance by 5,6,7,3',4'-pentamethoxyflavone (Sinensetin).
Biochemical and biophysical research communications 20020726
-
No evidence for a basal, retinoic, or superoxide-induced uncoupling activity of the uncoupling protein 2 present in spleen or lung mitochondria.
The Journal of biological chemistry 20020719
-
Effects of various principles from Chinese herbal medicine on rhodamine123 accumulation in brain capillary endothelial cells.
Acta pharmacologica Sinica 20020701
-
Nucleotide binding and nucleotide hydrolysis properties of the ABC transporter MRP6 (ABCC6).
Biochemistry 20020625
-
Effects of grapefruit juice and orange juice on the intestinal efflux of P-glycoprotein substrates.
Pharmaceutical research 20020601
-
MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine.
British journal of clinical pharmacology 20020501
-
Protective effect of L-carnosine against 12-O-tetradecanoylphorbol-13-acetate- or hydrogen peroxide-induced apoptosis on v-myc transformed rat liver epithelial cells.
Cancer letters 20020408
-
Apoptosis susceptibility of tumor cells to arsenic trioxide and the inherent cellular level of reactive oxygen species.
Chinese medical journal 20020401
-
The inhibition of calcium signaling in T lymphocytes from old mice results from enhanced activation of the mitochondrial permeability transition pore.
Mechanisms of ageing and development 20020331
-
Impact of BCRP/MXR, MRP1 and MDR1/P-Glycoprotein on thermoresistant variants of atypical and classical multidrug resistant cancer cells.
International journal of cancer 20020220
-
Evaluation of the clinical relevance of the expression and function of P-glycoprotein, multidrug resistance protein and lung resistance protein in patients with primary acute myelogenous leukemia.
Leukemia research 20020201
-
Bromocriptine reverses P-glycoprotein-mediated multidrug resistance in tumor cells.
Japanese journal of cancer research : Gann 20020201
-
Microplate screening of the differential effects of test agents on Hoechst 33342, rhodamine 123, and rhodamine 6G accumulation in breast cancer cells that overexpress P-glycoprotein.
Journal of biomolecular screening 20020201
-
Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols.
Biochimica et biophysica acta 20020130
-
Transport activity and surface expression of the Na+-Ca2+ exchanger NCX1 are inhibited by the immunosuppressive agent cyclosporin A and by the nonimmunosuppressive agent PSC833.
The Journal of biological chemistry 20020125
-
Nitric oxide induces apoptosis by activating K+ channels in pulmonary vascular smooth muscle cells.
American journal of physiology. Heart and circulatory physiology 20020101
-
Alternative metabolic pathways for energy supply and resistance to apoptosis in Fanconi anaemia.
Mutagenesis 20020101
-
Aluminum toxicity is associated with mitochondrial dysfunction and the production of reactive oxygen species in plant cells.
Plant physiology 20020101
-
Metabolic responses of cultured cells to oxygenated perfluorocarbon.
Artificial cells, blood substitutes, and immobilization biotechnology 20020101
-
In vivo use of all-trans retinoic acid prior to induction chemotherapy improves complete remission rate and increases rhodamine 123 uptake in patients with de novo acute myeloid leukemia.
Medical oncology (Northwood, London, England) 20020101
-
Overexpression of protein disulfide isomerase-like protein in a mouse leukemia L1210 cell line selected for resistance to 4-methyl-5-amino-1-formylisoquinoline thiosemicarbazone, a ribonucleotide reductase inhibitor.
Advances in enzyme regulation 20020101
-
Flow cytometric determination of cytoplasmic oxidants and mitochondrial membrane potential in neuronal cells.
Methods in enzymology 20020101
-
Characterization of tropane alkaloid aromatic esters that reverse the multidrug-resistance phenotype.
Anticancer research 20020101
-
Tumor sensitivity to anti-cancer drugs predicted by changes in fluorescence intensity and polarization in vitro.
Anticancer research 20020101
-
Increased reactive oxygen species production with antisense oligonucleotides directed against uncoupling protein 2 in murine endothelial cells.
Biochemistry and cell biology = Biochimie et biologie cellulaire 20020101
-
Photosensitizer accumulation in spontaneous multidrug resistant cells: a comparative study with Rhodamine 123, Rose Bengal acetate and Photofrine.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20020101
-
Saint John's wort: an in vitro analysis of P-glycoprotein induction due to extended exposure.
British journal of pharmacology 20011201
-
Staining of cellular mitochondria with LDS-751.
Journal of immunological methods 20011101
-
Leishmanicidal, antiplasmodial, and cytotoxic activity of novel diterpenoid 1,2-quinones from Perovskia abrotanoides: new source of tanshinones.
Journal of natural products 20011101
-
The farnesyl protein transferase inhibitor SCH66336 is a potent inhibitor of MDR1 product P-glycoprotein.
Cancer research 20011015
-
Inhibitors of mdr1-dependent transport activity delay accumulation of the mdr1 substrate rhodamine 123 in primary rat hepatocyte cultures.
Toxicology 20011005
-
Expression of MRP1 and related transporters in human lung cells in culture.
Toxicology 20011005
-
Augmented K(+) currents and mitochondrial membrane depolarization in pulmonary artery myocyte apoptosis.
American journal of physiology. Lung cellular and molecular physiology 20011001
-
Expression and functional activity of P-glycoprotein in cultured hepatocytes from Oncorhynchus mykiss.
American journal of physiology. Regulatory, integrative and comparative physiology 20011001
-
Intracellular levels of two cyclosporin derivatives valspodar (PSC 833) and cyclosporin a closely associated with multidrug resistance-modulating activity in sublines of human colorectal adenocarcinoma HCT-15.
Japanese journal of cancer research : Gann 20011001
-
Influence of multidrug resistance (MDR) proteins at the blood-brain barrier on the transport and brain distribution of enaminone anticonvulsants.
Journal of pharmaceutical sciences 20011001
-
Purification and some properties of an inhibitor for a yeast pleiotropic drug resistant pump from Kitasatospora sp. E-420.
Bioscience, biotechnology, and biochemistry 20011001
-
Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells.
Cancer research 20010915
-
Glucose-induced oscillations in cytoplasmic free Ca2+ concentration precede oscillations in mitochondrial membrane potential in the pancreatic beta-cell.
The Journal of biological chemistry 20010914
-
Quercetin modifies reactive oxygen levels but exerts only partial protection against oxidative stress within HL-60 cells.
Biochimica et biophysica acta 20010903
-
Cells from chronic myelogenous leukaemia patients at presentation exhibit multidrug resistance not mediated by either MDR1 or MRP1.
British journal of haematology 20010901
-
Ultrasound-Induced hyperthermia increases cellular uptake and cytotoxicity of P-glycoprotein substrates in multi-drug resistant cells.
Pharmaceutical research 20010901
-
HIV-protease inhibitors contribute to P-glycoprotein efflux function defect in peripheral blood lymphocytes from HIV-positive patients receiving HAART.
Journal of acquired immune deficiency syndromes (1999) 20010801
-
Mechanisms of taxotere-related drug resistance in pancreatic carcinoma.
The Journal of surgical research 20010801
-
Effect of chronic renal failure on the expression and function of rat intestinal P-glycoprotein in drug excretion.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010801
-
Functional expression of multidrug resistance protein 1 in Pichia pastoris.
Biochemistry 20010727
-
Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells.
Biochemical and biophysical research communications 20010706
-
Delocalized lipophilic cations selectively target the mitochondria of carcinoma cells.
Advanced drug delivery reviews 20010702
-
Methadone inhibits rhodamine123 transport in Caco-2 cells.
Drug metabolism and disposition: the biological fate of chemicals 20010701
-
Permeability of the peptidic GH secretagogues hexarelin and EP 51389, across rat jejunum.
Peptides 20010701
-
Apoptosis induced by doxorubicin and cinchonine in P388 multidrug-resistant cells.
The Journal of pharmacy and pharmacology 20010701
-
Decreased expression of P-glycoprotein in interleukin-1beta and interleukin-6 treated rat hepatocytes.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20010701
-
Effect of P-glycoprotein modulators on the human extraneuronal monoamine transporter.
European journal of pharmacology 20010622
-
Modulation by LY335979 of P-glycoprotein function in multidrug-resistant cell lines and human natural killer cells.
Biochemical pharmacology 20010601
-
A decrease in intracellular zinc level precedes the detection of early indicators of apoptosis in HL-60 cells.
Apoptosis : an international journal on programmed cell death 20010601
-
Protein kinase C and phosphatidylinositol 3-kinase independently contribute to P-glycoprotein-mediated drug secretion in the mouse proximal tubule.
Pflugers Archiv : European journal of physiology 20010601
-
Interactions between P-glycoprotein and drugs used in the supportive care of acute myeloid leukemia patients.
Leukemia & lymphoma 20010601
-
The relative quiescence of hematopoietic stem cells in nonhuman primates.
Blood 20010515
-
Hypersensitization of tumor cells to glycolytic inhibitors.
Biochemistry 20010508
-
P-glycoprotein efflux pump expression and activity in Calu-3 cells.
Journal of pharmaceutical sciences 20010501
-
Two rhodamine derivatives: 9-[2-(ethoxycarbonyl)phenyl]-3,6-bis-(ethylamino)-2,7-dimethylxanthylium chloride monohydrate and 3,6-diamino-9-[2-(methoxycarbonyl)-phenyl]xanthylium chloride trihydrate.
Acta crystallographica. Section C, Crystal structure communications 20010501
-
Increase in doxorubicin cytotoxicity by inhibition of P-glycoprotein activity with lomerizine.
Biological & pharmaceutical bulletin 20010501
-
Nuclear shrinkage in live mouse hippocampal slices.
Acta neuropathologica 20010501
-
Activation of K+ channels induces apoptosis in vascular smooth muscle cells.
American journal of physiology. Cell physiology 20010401
-
Overcoming multi-drug resistance using an intracellular anti-MDR1 sFv.
International journal of cancer 20010401
-
Ca2+ signalling and changes of mitochondrial function during low-Mg2+-induced epileptiform activity in organotypic hippocampal slice cultures.
The European journal of neuroscience 20010401
-
In vitro and in vivo tracer characteristics of an established multidrug-resistant human colon cancer cell line.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20010401
-
Fixation and permanent mounting of fluorescent probes after vital labelling of cultured cells.
Acta histochemica 20010401
-
[The leading role of mitochondrial depolarization in the mechanism of glutamate-induced disorder in Ca(2+)-homeostasis].
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20010401
-
Apoptosis and adaptive responses to oxidative stress in human endothelial cells exposed to cyclosporin A correlate with BCL-2 expression levels.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010301
-
Effects of Taxotere on invasive potential and multidrug resistance phenotype in pancreatic carcinoma cell line SUIT-2.
World journal of gastroenterology 20010215
-
Pharmacokinetic interaction of cytochrome P450 3A-related compounds with rhodamine 123, a P-glycoprotein substrate, in rats pretreated with dexamethasone.
Drug metabolism and disposition: the biological fate of chemicals 20010201
-
Differential sensitization by orobol in proliferating and quiescent human ovarian carcinoma cells.
International journal of oncology 20010201
-
Monitoring of cellular resistance to cancer chemotherapy: drug retention and efflux.
Methods in cell biology 20010101
-
P-glycoprotein-mediated drug secretion in mouse proximal tubule perfused in vitro.
Journal of the American Society of Nephrology : JASN 20010101
-
Regulation of cyclosporin A sensitive mitochondrial permeability transition by the redox state of pyridine nucleotides.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010101
-
A human lymphocyte based ex vivo assay to study the effect of drugs on P-glycoprotein (P-gp) function.
Pharmaceutical research 20010101
-
P-glycoprotein in HK-2 proximal tubule cell line.
Renal failure 20010101
-
Impact of proliferative activity and tumorigenic conversion on mitochondrial function of fibroblasts in 2D and 3D culture.
Cell biology international 20010101
-
Optical detection of mitochondrial NADH content in intact human myotubes.
Cellular and molecular biology (Noisy-le-Grand, France) 20010101
-
[Multidrug resistance of leukemia cells to cytostatics--the functional fluorescent dye efflux assay evaluated by flow cytometry].
Vnitrni lekarstvi 20010101
-
Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein.
Molecular pharmacology 20000101
-
Prostate apoptosis response-4 mediates trophic factor withdrawal-induced apoptosis of hippocampal neurons: actions prior to mitochondrial dysfunction and caspase activation.
Journal of neurochemistry 19990801
-
Contribution of mdr1b-type P-glycoprotein to okadaic acid resistance in rat pituitary GH3 cells.
Naunyn-Schmiedeberg's archives of pharmacology 19990801
-
Characterization of anti-Toxoplasma activity of SDZ 215-918, a cyclosporin derivative lacking immunosuppressive and peptidyl-prolyl-isomerase-inhibiting activity: possible role of a P glycoprotein in Toxoplasma physiology.
Antimicrobial agents and chemotherapy 19970901
-
Rapid loss in the mitochondrial membrane potential during geranylgeranoic acid-induced apoptosis.
Biochemical and biophysical research communications 19970103
-
Combined cytotoxic effects of tamoxifen and chemotherapeutic agents on bladder cancer cells: a potential use in intravesical chemotherapy.
British journal of urology 19960101
-
Toxicity of the mitochondrial poison dequalinium chloride in a murine model system.
Journal of pharmaceutical sciences 19930301
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Dequalinium, a topical antimicrobial agent, displays anticarcinoma activity based on selective mitochondrial accumulation.
Proceedings of the National Academy of Sciences of the United States of America 19870801