627-95-2 | 5-Aminovaleric acid hydrochloride

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$21.00	$15.00
25g	98%	in stock	$94.00	$66.00
100g	98%	in stock	$356.00	$249.00

Description

• Catalog Number: AB68813
• Chemical Name: 5-Aminovaleric acid hydrochloride
• CAS Number: 627-95-2
• Molecular Formula: C5H12ClNO2
• Molecular Weight: 153.6073
• MDL Number: MFCD00012919
• SMILES: NCCCCC(=O)O.Cl

Computed Properties

• Complexity: 72.8
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 4

Literature

• Synthesis and biological evaluation of copper-64 radiolabeled [DUPA-6-Ahx-(NODAGA)-5-Ava-BBN(7-14)NH2], a novel bivalent targeting vector having affinity for two distinct biomarkers (GRPr/PSMA) of prostate cancer.

  Nuclear medicine and biology 20140401

• Evaluation of collagen alteration after topical photodynamic therapy (PDT) using second harmonic generation (SHG) microscopy--in vivo study in a mouse model.

  Photodiagnosis and photodynamic therapy 20120601

• An integrated diagnosis and therapeutic system using intra-operative 5-aminolevulinic-acid-induced fluorescence guided robotic laser ablation for precision neurosurgery.

  Medical image analysis 20120401

• Solid-state NMR analyses reveal the structure dependence of the molecular dynamics for ω-amino acids.

  The journal of physical chemistry. B 20120223

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Phagocytosis of biocompatible gold nanoparticles.

  Langmuir : the ACS journal of surfaces and colloids 20100921

• Uptake and kinetics of 5-aminolevulinic acid in oral squamous cell carcinoma.

  International journal of oral and maxillofacial surgery 20100801

• Giant basal cell carcinoma of the breast mimicking paget's disease: complete remission after photodynamic therapy.

  Onkologie 20100101

• Dissociated learning using GABAergic drugs.

  Neuroscience and behavioral physiology 20090201

• The chemistry of escapin: identification and quantification of the components in the complex mixture generated by an L-amino acid oxidase in the defensive secretion of the sea snail Aplysia californica.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090101

• Synthesis and structural study of cyclic 5-aminovaleric acid-linked beta-Ala-beta-Ala dipeptides.

  Bioorganic & medicinal chemistry letters 20081115

• [Dissociated learning with GABAergic drugs].

  Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20080101

• Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes.

  Molecular systems biology 20080101

• Synthesis of lipophilic 2-oxoamides based on gamma-aminobutyric and delta-aminovaleric analogues and their activity against phospholipase A2.

  Journal of peptide science : an official publication of the European Peptide Society 20071001

• New chemotactic dimeric peptides show high affinity and potency at the human formylpeptide receptor.

  European journal of pharmacology 20070712

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Role of gamma-aminobutyricacidB(GABA(B)) receptors in the regulation of kainic acid-induced cell death in mouse hippocampus.

  Experimental & molecular medicine 20051231

• Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's disease.

  Journal of neurochemistry 20030301

• Mitochondrial and endoplasmic reticulum stress-induced apoptotic pathways are activated by 5-aminolevulinic acid-based photodynamic therapy in HL60 leukemia cells.

  Journal of photochemistry and photobiology. B, Biology 20030201

• A new turn structure for the formation of beta-hairpins in peptides.

  Journal of the American Chemical Society 20030129

• Transient state kinetic investigation of 5-aminolevulinate synthase reaction mechanism.

  The Journal of biological chemistry 20021122

• Search for the optimal linker in tandem hairpin polyamides.

  Bioorganic & medicinal chemistry 20021001

• Indirect presynaptic modulation of striatal dopamine release by GABA(B) receptors in the rat substantia nigra.

  Neuroscience letters 20020531

• Synthesis and biological evaluation in vitro of selective, high affinity peptide antagonists of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1.

  Biochemistry 20020521

• Pallidal administrations of gabazine and 5-AVA affect pressure-induced behavioral disorders in rats.

  Pharmacology, biochemistry, and behavior 20020101

• Synthesis and hybridization studies of a 5-aminopentanoic acid nucleobase (APN) dimer.

  Nucleosides, nucleotides & nucleic acids 20020101

• The influence of gabaergic drugs upon LH secretion from the pituitary of the common carp: an in vitro study.

  Reproductive biology 20011101

• Convenient method for the determination of arginine and its related compounds in rumen fluid by reversed-phase high-performance liquid chromatography.

  Journal of chromatography. B, Biomedical sciences and applications 20010505

• Behavioral actions of baclofen in the rat ventromedial thalamic nucleus: antagonism by delta-aminovalerate.

  Brain research 19870929

• Anticonvulsant activity of glycylglycine and delta-aminovaleric acid: evidence for glutamine exchange in amino acid transport.

  Journal of neurochemistry 19830401