62965-35-9 | Boc-Tle-OH

Packsize	Purity	Availability	Price	Discounted Price
25g	98%	in stock	$13.00	$9.00
50g	98%	in stock	$15.00	$10.00
100g	98%	in stock	$16.00	$11.00
500g	98%	in stock	$55.00	$38.00

Description

• Catalog Number: AI54018
• Chemical Name: Boc-Tle-OH
• CAS Number: 62965-35-9
• Molecular Formula: C26H33NO2
• Molecular Weight: 391.5457
• MDL Number: MFCD00065574
• SMILES: CC(=O)O[C@H]1CC[C@]2(C(=CC[C@@H]3[C@H]2CC[C@]2([C@@H]3CC=C2c2cccnc2)C)C1)C

Computed Properties

• Complexity: 273
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 5
• XLogP3: 2.3

Upstream Synthesis Route

N-tert-Butoxycarbonyl-L-tert-leucine (Boc-Leu-OH) is a versatile compound widely used in chemical synthesis as a protecting group for amino acids. This compound is specifically designed to protect the amino group (NH2) in the leucine molecule during various chemical reactions. By attaching the Boc group to the amino group, it effectively shields the reactive sites, allowing for selective manipulation of other functional groups without affecting the amino group's reactivity.In peptide synthesis, Boc-Leu-OH plays a crucial role in the stepwise assembly of peptides by protecting the amino group of leucine residues. This protection strategy ensures proper regioselectivity and prevents unwanted side reactions, allowing for efficient peptide bond formation. Additionally, Boc-Leu-OH can be selectively removed under mild acidic conditions, enabling the deprotection of the amino group without affecting other functional groups in the peptide chain.Overall, N-tert-Butoxycarbonyl-L-tert-leucine serves as a valuable tool in chemical synthesis, providing chemists with precise control over the protection and deprotection of amino groups in complex molecules. Its applications extend beyond peptide synthesis to various organic reactions where selective protection of amino groups is required for successful synthesis pathways.