645-12-5 | 5-Nitro-2-furoic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$18.00	$13.00
5g	95%	in stock	$48.00	$34.00
25g	95%	in stock	$229.00	$160.00
100g	98%	in stock	$869.00	$608.00

Description

• Catalog Number: AB69460
• Chemical Name: 5-Nitro-2-furoic acid
• CAS Number: 645-12-5
• Molecular Formula: C5H3NO5
• Molecular Weight: 157.0810
• MDL Number: MFCD00003240
• SMILES: OC(=O)c1ccc(o1)[N+](=O)[O-]
• NSC Number: 6452

Computed Properties

• Complexity: 186
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1

Literature

• Synthesis of some new [1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b][1,3,4] thiadiazoles starting from 5-nitro-2-furoic acid and evaluation of their antimicrobial activity.

  Bioorganic & medicinal chemistry 20110801

• Structural and biochemical study on the inhibitory activity of derivatives of 5-nitro-furan-2-carboxylic acid for RNase H function of HIV-1 reverse transcriptase.

  Bioorganic & medicinal chemistry 20110115

• 5-Nitro-2-furoic acid hydrazones: design, synthesis and in vitro antimycobacterial evaluation against log and starved phase cultures.

  Bioorganic & medicinal chemistry letters 20100801

• Synthesis of new and potent analogues of anti-tuberculosis agent 5-nitro-furan-2-carboxylic acid 4-(4-benzyl-piperazin-1-yl)-benzylamide with improved bioavailability.

  Bioorganic & medicinal chemistry letters 20060515

• Synthesis and evaluation of cyclic secondary amine substituted phenyl and benzyl nitrofuranyl amides as novel antituberculosis agents.

  Journal of medicinal chemistry 20051229