65-46-3 | Cytidine

Packsize	Purity	Availability	Price	Discounted Price
5g	99%	in stock	$6.00	$4.00
10g	98%	in stock	$9.00	$6.00
25g	98%	in stock	$18.00	$12.00
100g	95%	in stock	$57.00	$40.00
500g	95%	in stock	$69.00	$49.00

Description

• Catalog Number: AB45827
• Chemical Name: Cytidine
• CAS Number: 65-46-3
• Molecular Formula: C9H13N3O5
• Molecular Weight: 243.2166
• MDL Number: MFCD00006545
• SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1ccc(nc1=O)N

Computed Properties

• Complexity: 383
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 2
• XLogP3: -2.1

Literature

• A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model.

  Journal of inherited metabolic disease 20160101

• Use of 2'-spirocyclic ethers in HCV nucleoside design.

  Journal of medicinal chemistry 20140313

• Digalloylresveratrol, a novel resveratrol analog inhibits the growth of human pancreatic cancer cells.

  Investigational new drugs 20131001

• APC and DNA demethylation in cell fate specification and intestinal cancer.

  Advances in experimental medicine and biology 20130101

• DNA methyltransferase inhibitor zebularine inhibits human hepatic carcinoma cells proliferation and induces apoptosis.

  PloS one 20130101

• DNA methylation program in developing hippocampus and its alteration by alcohol.

  PloS one 20130101

• Expanding the molecular recognition repertoire of antifreeze polypeptides: effects on nucleoside crystal growth.

  Chemical communications (Cambridge, England) 20121207

• A facile synthetic route to diazepinone derivatives via ring closing metathesis and its application for human cytidine deaminase inhibitors.

  Chemical communications (Cambridge, England) 20121204

• Antileukemic activity of combined epigenetic agents, DNMT inhibitors zebularine and RG108 with HDAC inhibitors, against promyelocytic leukemia HL-60 cells.

  Cellular & molecular biology letters 20121201

• Specific interactions between adenosine and streptavidin/avidin.

  Bioorganic & medicinal chemistry letters 20121201

• Anti-hepatitis B virus activities of α-DDB-FNC, a novel nucleoside-biphenyldicarboxylate compound in cells and ducks, and its anti-immunological liver injury effect in mice.

  Antiviral research 20121201

• The mitochondrial Amidoxime Reducing Component (mARC) is involved in detoxification of N-hydroxylated base analogues.

  Chemical research in toxicology 20121119

• Inhibition of norovirus replication by the nucleoside analogue 2'-C-methylcytidine.

  Biochemical and biophysical research communications 20121102

• Contribution of AT-, GC-, and methylated cytidine-rich DNA to chromatin composition in Malpighian tubule cell nuclei of Panstrongylus megistus (Hemiptera, Reduviidae).

  Acta histochemica 20121101

• Cytotoxicity of new duplex drugs linking 3'-C-ethynylcytidine and 5-fluor-2'-deoxyuridine against human melanoma cells.

  International journal of cancer 20121101

• Polymorphisms of the acid sensing histidine kinase gene arsS in Helicobacter pylori populations from anatomically distinct gastric sites.

  Microbial pathogenesis 20121101

• Using multiplex single-base extension typing to screen for mutants defective in RNA editing.

  Nature protocols 20121101

• ENDOR spectroscopy and DFT calculations: evidence for the hydrogen-bond network within α2 in the PCET of E. coli ribonucleotide reductase.

  Journal of the American Chemical Society 20121024

• Synthesis of a fluorescently tagged sialic acid analogue useful for live-cell imaging.

  Chemical communications (Cambridge, England) 20121009

• Cytidine deaminase single-nucleotide polymorphism is predictive of toxicity from gemcitabine in patients with pancreatic cancer: RTOG 9704.

  The pharmacogenomics journal 20121001

• Genotype frequencies of drug-metabolizing enzymes responsible for purine and pyrimidine antagonists in a healthy Asian-Indian population.

  Biochemical genetics 20121001

• Zebularine inhibits the growth of HeLa cervical cancer cells via cell cycle arrest and caspase-dependent apoptosis.

  Molecular biology reports 20121001

• Chemical modification study of antisense gapmers.

  Nucleic acid therapeutics 20121001

• Omega-3 fatty acid treatment, with or without cytidine, fails to show therapeutic properties in bipolar disorder: a double-blind, randomized add-on clinical trial.

  Journal of clinical psychopharmacology 20121001

• The APOBEC3C crystal structure and the interface for HIV-1 Vif binding.

  Nature structural & molecular biology 20121001

• On the evolution of one-electron-oxidized deoxyguanosine in damaged DNA under physiological conditions: a DFT and ONIOM study on proton transfer and equilibrium.

  Physical chemistry chemical physics : PCCP 20120928

• Benchmark studies on the building blocks of DNA. 2. Effect of biological environment on the electronic excitation spectrum of nucleobases.

  The journal of physical chemistry. A 20120906

• Reactions of an osmium-hexahydride complex with cytosine, deoxycytidine, and cytidine: the importance of the minor tautomers.

  Inorganic chemistry 20120903

• Activation-induced cytidine deaminase (AID) linking immunity, chronic inflammation, and cancer.

  Cancer immunology, immunotherapy : CII 20120901

• Synthesis and biological evaluation of oral prodrugs based on the structure of gemcitabine.

  Chemical biology & drug design 20120901

• AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation.

  Nature chemical biology 20120901

• Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.

  Journal of immunology (Baltimore, Md. : 1950) 20120901

• Reassessing genomic targeting of AID.

  Nature immunology 20120901

• Association analysis of clinical aspects and vitamin D receptor gene polymorphism with external apical root resorption in orthodontic patients.

  American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 20120901

• Synthesis of glucopyranosyl Schiff base zinc(II) complexes capable of interacting with mononucleotides, and their DNA-cleavage activities.

  Chemistry & biodiversity 20120901

• Two interacting proteins are necessary for the editing of the NdhD-1 site in Arabidopsis plastids.

  The Plant cell 20120901

• APOBEC3G inhibits microRNA-mediated repression of translation by interfering with the interaction between Argonaute-2 and MOV10.

  The Journal of biological chemistry 20120824

• D282, a non-nucleoside inhibitor of influenza virus infection that interferes with de novo pyrimidine biosynthesis.

  Antiviral chemistry & chemotherapy 20120821

• Efficient preparation of 2,4-diaminopyrimidine nucleosides: total synthesis of lysidine and agmatidine.

  Organic letters 20120817

• High incidence of severe neutropenia after gemcitabine-based chemotherapy in Chinese cancer patients with CDA 79A>C mutation.

  Clinica chimica acta; international journal of clinical chemistry 20120816

• APOBEC3G expression and hypermutation are inversely associated with human immunodeficiency virus type 1 (HIV-1) burden in vivo.

  Virology 20120815

• Flight of a cytidine deaminase complex with an imperfect transition state analogue inhibitor: mass spectrometric evidence for the presence of a trapped water molecule.

  Biochemistry 20120814

• Nanoscale structure and dynamics of ABOBEC3G complexes with single-stranded DNA.

  Biochemistry 20120814

• A new imidazolium-embedded C18 stationary phase with enhanced performance in reversed-phase liquid chromatography.

  Analytica chimica acta 20120813

• A structural basis for the biochemical behavior of activation-induced deoxycytidine deaminase class-switch recombination-defective hyper-IgM-2 mutants.

  The Journal of biological chemistry 20120810

• The HIV reverse transcriptase inhibitor tenofovir induces cell cycle arrest in human cancer cells.

  Investigational new drugs 20120801

• Prevention of age-related changes in hippocampal levels of 5-methylcytidine by caloric restriction.

  Neurobiology of aging 20120801

• SL-01, an oral gemcitabine derivative, inhibited human cancer growth more potently than gemcitabine.

  Toxicology and applied pharmacology 20120801

• Epigenomic silencing of the BMP-4 gene in pituitary adenomas: a potential target for epidrug-induced re-expression.

  Endocrinology 20120801

• Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism.

  The Journal of clinical investigation 20120801

• APOBEC3G enhances lymphoma cell radioresistance by promoting cytidine deaminase-dependent DNA repair.

  Blood 20120712

• Supramolecular polymerization of oligopyrenotides--control by single, natural nucleotides.

  Organic & biomolecular chemistry 20120707

• Chirality effects on the IRMPD spectra of basket resorcinarene/nucleoside complexes.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20120702

• Stabilised DNA secondary structures with increasing transcription localise hypermutable bases for somatic hypermutation in IGHV3-23.

  Immunogenetics 20120701

• Unraveling the concentration-dependent metabolic response of Pseudomonas sp. HF-1 to nicotine stress by ¹H NMR-based metabolomics.

  Ecotoxicology (London, England) 20120701

• The role of activation-induced cytidine deaminase in lymphomagenesis.

  Current opinion in hematology 20120701

• Crystal and solution structures of methyltransferase RsmH provide basis for methylation of C1402 in 16S rRNA.

  Journal of structural biology 20120701

• Bacillus anthracis edema factor substrate specificity: evidence for new modes of action.

  Toxins 20120701

• Immunoglobulin class-switch DNA recombination: induction, targeting and beyond.

  Nature reviews. Immunology 20120625

• APOBEC3B and AID have similar nuclear import mechanisms.

  Journal of molecular biology 20120622

• Iron inhibits activation-induced cytidine deaminase enzymatic activity and modulates immunoglobulin class switch DNA recombination.

  The Journal of biological chemistry 20120615

• Design, synthesis, and spectroscopic properties of extended and fused pyrrolo-dC and pyrrolo-C analogs.

  Organic letters 20120615

• Concomitant lethal mutagenesis of human immunodeficiency virus type 1.

  Journal of molecular biology 20120608

• APOBEC3-mediated editing in HIV type 1 from pediatric patients and its association with APOBEC3G/CUL5 polymorphisms and Vif variability.

  AIDS research and human retroviruses 20120601

• An epigenetic mechanism for high, synergistic expression of indoleamine 2,3-dioxygenase 1 (IDO1) by combined treatment with zebularine and IFN-γ: potential therapeutic use in autoimmune diseases.

  Molecular immunology 20120601

• Affinity maturation of anti-TNF-alpha scFv with somatic hypermutation in non-B cells.

  Protein & cell 20120601

• Strikingly different properties of uracil-DNA glycosylases UNG2 and SMUG1 may explain divergent roles in processing of genomic uracil.

  DNA repair 20120601

• Accurate identification of human Alu and non-Alu RNA editing sites.

  Nature methods 20120601

• Adenosine modification may be preferred for reducing siRNA immune stimulation.

  Nucleic acid therapeutics 20120601

• DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation.

  Nature immunology 20120601

• Association of polymorphisms of cytosine arabinoside-metabolizing enzyme gene with therapeutic efficacy for acute myeloid leukemia.

  Chinese medical journal 20120601

• Azacitidine: a review of its use in the management of myelodysplastic syndromes/acute myeloid leukaemia.

  Drugs 20120528

• Mutational processes molding the genomes of 21 breast cancers.

  Cell 20120525

• Synthesis and biological evaluation of fatty acyl ester derivatives of (-)-2',3'-dideoxy-3'-thiacytidine.

  Journal of medicinal chemistry 20120524

• [Oxidation and deamination of nucleobases as an epigenetic tool].

  Postepy higieny i medycyny doswiadczalnej (Online) 20120524

• AID-driven deletion causes immunoglobulin heavy chain locus suicide recombination in B cells.

  Science (New York, N.Y.) 20120518

• Signals in APOBEC3F N-terminal and C-terminal deaminase domains each contribute to encapsidation in HIV-1 virions and are both required for HIV-1 restriction.

  The Journal of biological chemistry 20120511

• Single-stranded DNA scanning and deamination by APOBEC3G cytidine deaminase at single molecule resolution.

  The Journal of biological chemistry 20120504

• Synthesis of (6-(13)C)pyrimidine nucleotides as spin-labels for RNA dynamics.

  Journal of the American Chemical Society 20120502

• Inhibition of EGFR phosphorylation in a panel of human breast cancer cells correlates with synergistic interactions between gefitinib and 5'-DFUR, the bioactive metabolite of Xeloda.

  Breast cancer research and treatment 20120501

• Functions and regulation of the APOBEC family of proteins.

  Seminars in cell & developmental biology 20120501

• Germline polymorphisms in patients with advanced nonsmall cell lung cancer receiving first-line platinum-gemcitabine chemotherapy: a prospective clinical study.

  Cancer 20120501

• Identification of cda gene in bighead carp and its expression in response to microcystin-LR.

  Ecotoxicology and environmental safety 20120501

• Fluorescence and electrochemical recognition of nucleosides and DNA by a novel luminescent bioprobe Eu(III)-TNB.

  Journal of fluorescence 20120501

• Alteration of DNA demethylation dynamics by in vitro culture conditions in rabbit pre-implantation embryos.

  Epigenetics 20120501

• Discovery of 4'-azido-2'-deoxy-2'-C-methyl cytidine and prodrugs thereof: a potent inhibitor of Hepatitis C virus replication.

  Bioorganic & medicinal chemistry letters 20120501

• Monocytoid B cells: an enigmatic B cell subset showing evidence of extrafollicular immunoglobulin gene somatic hypermutation.

  Scandinavian journal of immunology 20120501

• Epstein-Barr virus infection of naïve B cells in vitro frequently selects clones with mutated immunoglobulin genotypes: implications for virus biology.

  PLoS pathogens 20120501

• A phase I study to determine the safety and pharmacokinetics of intravenous administration of TAS-106 once per week for three consecutive weeks every 28 days in patients with solid tumors.

  Anticancer research 20120501

• [IgH locus suicide recombination, or when B cells surrender!].

  Medecine sciences : M/S 20120501

• The nature of hydrogen bonds in cytidine···H+···cytidine DNA base pairs.

  Angewandte Chemie (International ed. in English) 20120423

• Hypermutation of ApoB mRNA by rat APOBEC-1 overexpression mimics APOBEC-3 hypermutation.

  Journal of molecular biology 20120420

• An evolutionary view of the mechanism for immune and genome diversity.

  Journal of immunology (Baltimore, Md. : 1950) 20120415

• Synthesis, gene silencing, and molecular modeling studies of 4'-C-aminomethyl-2'-O-methyl modified small interfering RNAs.

  The Journal of organic chemistry 20120406

• BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway.

  Nature communications 20120403

• Eosinophilic pneumonia associated with azacitidine in a patient with myelodysplastic syndrome.

  Respiratory care 20120401

• Differences in the enzymatic efficiency of human and bony fish AID are mediated by a single residue in the C terminus modulating single-stranded DNA binding.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120401

• In vivo enrichment of cytidine deaminase gene-modified hematopoietic cells by prolonged cytosine-arabinoside application.

  Cytotherapy 20120401

• Properties of N(4)-methylated cytidines in miRNA mimics.

  Nucleic acid therapeutics 20120401

• Higher incidence of C677T polymorphism of the MTHFR gene in North Indian patients with vascular disease.

  Vascular 20120401

• Separation of nucleobases and their derivatives with organic-high ionic strength aqueous phase systems by spiral high-speed counter-current chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120401

• Nucleoside and nucleobase analogs in cancer treatment: not only sapacitabine, but also gemcitabine.

  Expert opinion on investigational drugs 20120401

• Synthesis and biological evaluation of (3'S)-3'-deoxy-3'-fluoro-3'-C-ethynylcytidine.

  Nucleosides, nucleotides & nucleic acids 20120401

• Intraperitoneal administration of CDP-choline or a combination of cytidine plus choline improves nerve regeneration and functional recovery in a rat model of sciatic nerve injury.

  Neurological research 20120401

• The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombination.

  PLoS genetics 20120401

• Downregulation of Orai1 expression in the airway alleviates murine allergic rhinitis.

  Experimental & molecular medicine 20120331

• Targeting activation-induced cytidine deaminase prevents colon cancer development despite persistent colonic inflammation.

  Oncogene 20120329

• Imatinib mesylate directly impairs class switch recombination through down-regulation of AID: its potential efficacy as an AID suppressor.

  Blood 20120329

• 2'-Azido RNA, a versatile tool for chemical biology: synthesis, X-ray structure, siRNA applications, click labeling.

  ACS chemical biology 20120316

• Excessive activity of apolipoprotein B mRNA editing enzyme catalytic polypeptide 2 (APOBEC2) contributes to liver and lung tumorigenesis.

  International journal of cancer 20120315

• Molecular and functional interactions of cat APOBEC3 and feline foamy and immunodeficiency virus proteins: different ways to counteract host-encoded restriction.

  Virology 20120315

• Formation of new base pairs between inosine and 5-methyl-2-thiocytidine derivatives.

  Organic & biomolecular chemistry 20120314

• Hydrodynamic and functional analysis of HIV-1 Vif oligomerization.

  Biochemistry 20120313

• Preparation of methacrylate-based monolith for capillary hydrophilic interaction chromatography and its application in determination of nucleosides in urine.

  Journal of chromatography. A 20120309

• Preparation and chromatographic evaluation of a cysteine-bonded zwitterionic hydrophilic interaction liquid chromatography stationary phase.

  Journal of chromatography. A 20120309

• Dendritic cell-mediated activation-induced cytidine deaminase (AID)-dependent induction of genomic instability in human myeloma.

  Blood 20120308

• APOBEC2 is a monomer in solution: implications for APOBEC3G models.

  Biochemistry 20120306

• Modifications modulate anticodon loop dynamics and codon recognition of E. coli tRNA(Arg1,2).

  Journal of molecular biology 20120302

• The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria-mediated apoptosis and DNA damage in p53 mutant leukemic T cells.

  International journal of cancer 20120301

• Correlation of cytidine deaminase polymorphisms and activity with clinical outcome in gemcitabine-/platinum-treated advanced non-small-cell lung cancer patients.

  Annals of oncology : official journal of the European Society for Medical Oncology 20120301

• Expression of immunoglobulin G in esophageal squamous cell carcinomas and its association with tumor grade and Ki67.

  Human pathology 20120301

• Azacitidine for treatment of imminent relapse in MDS or AML patients after allogeneic HSCT: results of the RELAZA trial.

  Leukemia 20120301

• B-cell agonists up-regulate AID and APOBEC3G deaminases, which induce IgA and IgG class antibodies and anti-viral function.

  Immunology 20120301

• Role of activation-induced cytidine deaminase in the progression of follicular lymphoma.

  Cancer science 20120301

• The innate antiviral factor APOBEC3G targets replication of measles, mumps and respiratory syncytial viruses.

  The Journal of general virology 20120301

• Gene capture by Helitron transposons reshuffles the transcriptome of maize.

  Genetics 20120301

• Assisted reproduction treatment and epigenetic inheritance.

  Human reproduction update 20120301

• The role of HIV-1 Vpr in promoting the infection of nondividing cells and in cell cycle arrest.

  Current opinion in HIV and AIDS 20120301

• Unique biomarkers for B-cell function predict the serum response to pandemic H1N1 influenza vaccine.

  International immunology 20120301

• CDA deficiency as a possible culprit for life-threatening toxicities after cytarabine plus 6-mercaptopurine therapy: pharmacogenetic investigations.

  Pharmacogenomics 20120301

• Visualization and measurement of ATP levels in living cells replicating hepatitis C virus genome RNA.

  PLoS pathogens 20120301

• Antiproliferative and antitumor effects of azacitidine against the human myelodysplastic syndrome cell line SKM-1.

  Anticancer research 20120301

• APOBEC3G-induced hypermutation of human immunodeficiency virus type-1 is typically a discrete 'all or nothing' phenomenon.

  PLoS genetics 20120301

• Activation-induced cytidine deaminase mRNA expression in oral squamous cell carcinoma-derived cell lines is upregulated by inflammatory cytokines.

  Journal of oral science 20120301

• Drug interactions: the importance of looking inside cancer cells.

  Cancer discovery 20120301

• nab-Paclitaxel potentiates gemcitabine activity by reducing cytidine deaminase levels in a mouse model of pancreatic cancer.

  Cancer discovery 20120301

• Increased p190RhoGEF expression in activated B cells correlates with the induction of the plasma cell differentiation.

  Experimental & molecular medicine 20120227

• Activated ribonucleotides undergo a sugar pucker switch upon binding to a single-stranded RNA template.

  Journal of the American Chemical Society 20120227

• Biochemical characterization of recombinant β-glucosyltransferase and analysis of global 5-hydroxymethylcytosine in unique genomes.

  Biochemistry 20120207

• DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes.

  Nature 20120207

• Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine.

  Blood 20120202

• Phase I and pharmacokinetic study of 3'-C-ethynylcytidine (TAS-106), an inhibitor of RNA polymerase I, II and III,in patients with advanced solid malignancies.

  Investigational new drugs 20120201

• Combining molecular dynamics and docking simulations of the cytidine deaminase from Mycobacterium tuberculosis H37Rv.

  Journal of molecular modeling 20120201

• APOBEC3G/F as one possible driving force for co-receptor switch of the human immunodeficiency virus-1.

  Medical microbiology and immunology 20120201

• Elucidation of the time course of adenosine deaminase APOBEC3G and viral infectivity factor vif in HIV-2(287) -infected infant macaques.

  Journal of medical primatology 20120201

• DNA glycosylases: in DNA repair and beyond.

  Chromosoma 20120201

• TLR-mediated B cell defects and IFN-α in common variable immunodeficiency.

  Journal of clinical immunology 20120201

• Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1.

  The EMBO journal 20120201

• Biomass production of site selective 13C/15N nucleotides using wild type and a transketolase E. coli mutant for labeling RNA for high resolution NMR.

  Journal of biomolecular NMR 20120201

• DNA methyltransferase inhibitor, zebularine, delays tumor growth and induces apoptosis in a genetically engineered mouse model of breast cancer.

  Molecular cancer therapeutics 20120201

• Chemical fingerprint analysis of Fritillaria delavayi Franch. by high-performance liquid chromatography.

  Journal of separation science 20120201

• Stratification of nucleoside analog chemotherapy using 1-(2'-deoxy-2'-18F-fluoro-β-D-arabinofuranosyl)cytosine and 1-(2'-deoxy-2'-18F-fluoro-β-L-arabinofuranosyl)-5-methylcytosine PET.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120201

• Cytidine deaminase genetic variants influence RNA expression and cytarabine cytotoxicity in acute myeloid leukemia.

  Pharmacogenomics 20120201

• Multi-scale modeling of HIV infection in vitro and APOBEC3G-based anti-retroviral therapy.

  PLoS computational biology 20120201

• Negative supercoiling creates single-stranded patches of DNA that are substrates for AID-mediated mutagenesis.

  PLoS genetics 20120201

• Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.

  PLoS genetics 20120201

• Comparison of insertional RNA editing in Myxomycetes.

  PLoS computational biology 20120201

• Newly Identified TLR9 Stimulant, M6-395 Is a Potent Polyclonal Activator for Murine B Cells.

  Immune network 20120201

• Translocation capture sequencing: a method for high throughput mapping of chromosomal rearrangements.

  Journal of immunological methods 20120131

• Synthesis of conformationally North-locked pyrimidine nucleosides built on an oxabicyclo[3.1.0]hexane scaffold.

  The Journal of organic chemistry 20120120

• The RNase III enzyme Dicer is essential for germinal center B-cell formation.

  Blood 20120119

• The host restriction factor APOBEC3G and retroviral Vif protein coevolve due to ongoing genetic conflict.

  Cell host & microbe 20120119

• Injury-dependent Müller glia and ganglion cell reprogramming during tissue regeneration requires Apobec2a and Apobec2b.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20120118

• Identification of 3,N(4)-etheno-5-methyl-2'-deoxycytidine in human DNA: a new modified nucleoside which may perturb genome methylation.

  Chemical research in toxicology 20120113

• Gene polymorphisms, pharmacokinetics, and hematological toxicity in advanced non-small-cell lung cancer patients receiving cisplatin/gemcitabine.

  Cancer chemotherapy and pharmacology 20120101

• Modulation of microRNA expression and function by ADARs.

  Current topics in microbiology and immunology 20120101

• Mutations in epigenetic modifiers in myeloid malignancies and the prospect of novel epigenetic-targeted therapy.

  Advances in hematology 20120101

• Epigenetic changes by zebularine leading to enhanced differentiation of human promyelocytic leukemia NB4 and KG1 cells.

  Molecular and cellular biochemistry 20120101

• Immunoglobulin G expression and its colocalization with complement proteins in papillary thyroid cancer.

  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20120101

• Plastid signalling under multiple conditions is accompanied by a common defect in RNA editing in plastids.

  Journal of experimental botany 20120101

• Specific interactions between nucleolipid doped liposomes and DNA allow a more efficient polynucleotide condensation.

  Journal of colloid and interface science 20120101

• Molecular pathogenesis of cholangiocarcinoma.

  International journal of hepatology 20120101

• Growth arrest and DNA-damage-inducible, beta (GADD45b)-mediated DNA demethylation in major psychosis.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120101

• Morelloflavone, a biflavonoid inhibitor of migration-related kinases, ameliorates atherosclerosis in mice.

  American journal of physiology. Heart and circulatory physiology 20120101

• Deletion of the APOBEC3B gene strongly impacts susceptibility to falciparum malaria.

  Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20120101

• A molecular mechanism for TNF-α-mediated downregulation of B cell responses.

  Journal of immunology (Baltimore, Md. : 1950) 20120101

• The influence of gemcitabine pathway polymorphisms on treatment outcome in patients with malignant mesothelioma.

  Pharmacogenetics and genomics 20120101

• Prediction of a side effect and efficacy of adjuvant chemotherapy with gemcitabine for post operative patient of pancreatic cancer by a genetic polymorphism analysis.

  Hepato-gastroenterology 20120101

• APOBEC3 proteins and genomic stability: the high cost of a good defense.

  Cell cycle (Georgetown, Tex.) 20120101

• Long term cultured HL-60 cells are intrinsically resistant to Ara-C through high CDA activity.

  Frontiers in bioscience (Landmark edition) 20120101

• A CDD polymorphism as predictor of capecitabine-induced hand-foot syndrome--letter.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20120101

• Isolation and characterization of a murine P388 leukemia line resistant to thiarabine.

  Nucleosides, nucleotides & nucleic acids 20120101

• Locked nucleic acid flow cytometry-fluorescence in situ hybridization (LNA flow-FISH): a method for bacterial small RNA detection.

  Journal of visualized experiments : JoVE 20120101

• Effects of a novel DNA methyltransferase inhibitor Zebularine on human lens epithelial cells.

  Molecular vision 20120101

• Identification of a potential ovarian cancer stem cell gene expression profile from advanced stage papillary serous ovarian cancer.

  PloS one 20120101

• Evolution of the primate APOBEC3A cytidine deaminase gene and identification of related coding regions.

  PloS one 20120101

• Biapenem inactivation by B2 metallo β-lactamases: energy landscape of the post-hydrolysis reactions.

  PloS one 20120101

• HIV-1 polymerase inhibition by nucleoside analogs: cellular- and kinetic parameters of efficacy, susceptibility and resistance selection.

  PLoS computational biology 20120101

• Two genetic determinants acquired late in Mus evolution regulate the inclusion of exon 5, which alters mouse APOBEC3 translation efficiency.

  PLoS pathogens 20120101

• [Demethylating medication in myelodysplastic syndrome].

  Nederlands tijdschrift voor geneeskunde 20120101

• The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication.

  PLoS pathogens 20120101

• The HIV1 protein Vpr acts to enhance constitutive DCAF1-dependent UNG2 turnover.

  PloS one 20120101

• Competing pathways control host resistance to virus via tRNA modification and programmed ribosomal frameshifting.

  Molecular systems biology 20120101

• Insertion site preference of Mu, Tn5, and Tn7 transposons.

  Mobile DNA 20120101

• Complexity of murine cardiomyocyte miRNA biogenesis, sequence variant expression and function.

  PloS one 20120101

• Chemical approaches for structure and function of RNA in postgenomic era.

  Journal of nucleic acids 20120101

• Morphine suppresses IFN signaling pathway and enhances AIDS virus infection.

  PloS one 20120101

• The pyrimidine nucleotide biosynthetic pathway modulates production of biofilm determinants in Escherichia coli.

  PloS one 20120101

• Lysine residue at position 22 of the AID protein regulates its class switch activity.

  PloS one 20120101

• Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice.

  Antiviral therapy 20120101

• miRNA arm selection and isomiR distribution in gastric cancer.

  BMC genomics 20120101

• Mosquitoes LTR retrotransposons: a deeper view into the genomic sequence of Culex quinquefasciatus.

  PloS one 20120101

• Molecular targets of gemcitabine action: rationale for development of novel drugs and drug combinations.

  Current pharmaceutical design 20120101

• In-depth characterization of viral isolates from plasma and cells compared with plasma circulating quasispecies in early HIV-1 infection.

  PloS one 20120101

• Glucose metabolite glyoxal induces senescence in telomerase-immortalized human mesenchymal stem cells.

  Chemistry Central journal 20120101

• In planta assays involving epigenetically silenced genes reveal inhibition of cytosine methylation by genistein.

  Plant methods 20120101

• DNA methylation-independent reversion of gemcitabine resistance by hydralazine in cervical cancer cells.

  PloS one 20120101

• DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity.

  Radiation oncology (London, England) 20120101

• The AID dilemma: infection, or cancer?

  Advances in cancer research 20120101

• Activation-induced cytidine deaminase in antibody diversification and chromosome translocation.

  Advances in cancer research 20120101

• Reversal of cocaine-conditioned place preference through methyl supplementation in mice: altering global DNA methylation in the prefrontal cortex.

  PloS one 20120101

• Canonical A-to-I and C-to-U RNA editing is enriched at 3'UTRs and microRNA target sites in multiple mouse tissues.

  PloS one 20120101

• Comparison of the effects of adenosine, inosine, and their combination as an adjunct to reperfusion in the treatment of acute myocardial infarction.

  ISRN cardiology 20120101

• Challenging New Targets for CNS-HIV Infection.

  Frontiers in neurology 20120101

• Characterization of the interaction of full-length HIV-1 Vif protein with its key regulator CBFβ and CRL5 E3 ubiquitin ligase components.

  PloS one 20120101

• Multi-target siRNA based on DNMT3A/B homologous conserved region influences cell cycle and apoptosis of human prostate cancer cell line TSU-PR1.

  Genetics and molecular biology 20120101

• Genetic association studies of copy-number variation: should assignment of copy number states precede testing?

  PloS one 20120101

• The Chlamydia psittaci genome: a comparative analysis of intracellular pathogens.

  PloS one 20120101

• Vpu and BST2: Still Not There Yet?

  Frontiers in microbiology 20120101

• Engineering a hyperthermophilic archaeon for temperature-dependent product formation.

  mBio 20120101

• Focused examination of the intestinal lamina propria yields greater molecular insight into mechanisms underlying SIV induced immune dysfunction.

  PloS one 20120101

• The role of innate APOBEC3G and adaptive AID immune responses in HLA-HIV/SIV immunized SHIV infected macaques.

  PloS one 20120101

• The biased nucleotide composition of HIV-1 triggers type I interferon response and correlates with subtype D increased pathogenicity.

  PloS one 20120101

• The DNA glycosylases Ogg1 and Nth1 do not contribute to Ig class switching in activated mouse splenic B cells.

  PloS one 20120101

• Epigenetics and autoimmune diseases.

  Autoimmune diseases 20120101

• Present and Future of EGFR Inhibitors for Head and Neck Squamous Cell Cancer.

  Journal of oncology 20120101

• Apolipoprotein B mRNA-editing, catalytic polypeptide cytidine deaminases and retroviral restriction.

  Wiley interdisciplinary reviews. RNA 20120101

• Antibody repertoires in humanized NOD-scid-IL2Rγ(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse.

  PloS one 20120101

• Massively parallel haplotyping on microscopic beads for the high-throughput phase analysis of single molecules.

  PloS one 20120101

• IspE inhibitors identified by a combination of in silico and in vitro high-throughput screening.

  PloS one 20120101

• Innate immune complexity in the purple sea urchin: diversity of the sp185/333 system.

  Frontiers in immunology 20120101

• New option for management of HIV-1 infection in treatment-naive patients: once-daily, fixed-dose combination of rilpivirine-emtricitabine-tenofovir.

  HIV/AIDS (Auckland, N.Z.) 20120101

• Quantification of unintegrated HIV-1 DNA at the single cell level in vivo.

  PloS one 20120101

• Susceptibility of human lymphoid tissue cultured ex vivo to xenotropic murine leukemia virus-related virus (XMRV) infection.

  PloS one 20120101

• Tetrahydrouridine inhibits cell proliferation through cell cycle regulation regardless of cytidine deaminase expression levels.

  PloS one 20120101

• Electrochemical detection of individual single nucleotide polymorphisms using monobase-modified apoferritin-encapsulated nanoparticles.

  Biosensors & bioelectronics 20120101

• Bone marrow stromal cells modulate mouse ENT1 activity and protect leukemia cells from cytarabine induced apoptosis.

  PloS one 20120101

• Adenovirus-mediated double suicide gene selectively kills gastric cancer cells.

  Asian Pacific journal of cancer prevention : APJCP 20120101

• The Role of Elongin BC-Containing Ubiquitin Ligases.

  Frontiers in oncology 20120101

• Retrospective and observational study to assess the efficacy of citicoline in elderly patients suffering from stupor related to complex geriatric syndrome.

  Clinical interventions in aging 20120101

• Metal Ion Chelates as Surrogates of Nucleobases for the Recognition of Nucleic Acid Sequences: The Pd(2+) Complex of 2,6-Bis(3,5-dimethylpyrazol-1-yl)purine Riboside.

  Journal of nucleic acids 20120101

• Preparation and evaluation of polymeric microparticulates for improving cellular uptake of gemcitabine.

  International journal of nanomedicine 20120101

• Radiolabeled nucleosides for predicting and monitoring the cancer therapeutic efficacy of chemodrugs.

  Current medicinal chemistry 20120101

• Interplay between HIV-1 and Host Genetic Variation: A Snapshot into Its Impact on AIDS and Therapy Response.

  Advances in virology 20120101

• Studies on the restriction of murine leukemia viruses by mouse APOBEC3.

  PloS one 20120101

• Radiation, inflammation, and immune responses in cancer.

  Frontiers in oncology 20120101

• Self-assembled squalenoyl-cytarabine nanostructures as a potent nanomedicine for treatment of leukemic diseases.

  International journal of nanomedicine 20120101

• SIV replication in human cells.

  Frontiers in microbiology 20120101

• Antiretroviral drugs: critical issues and recent advances.

  Indian journal of pharmacology 20120101

• Interplay between human cytomegalovirus and intrinsic/innate host responses: a complex bidirectional relationship.

  Mediators of inflammation 20120101

• An initial in vitro investigation into the potential therapeutic use of SupT1 cells to prevent AIDS in HIV-seropositive individuals.

  PloS one 20120101

• Efficiency of purine utilization by Helicobacter pylori: roles for adenosine deaminase and a NupC homolog.

  PloS one 20120101

• Transgenerational effects of stress exposure on offspring phenotypes in apomictic dandelion.

  PloS one 20120101

• Antiviral Mechanism and Biochemical Basis of the Human APOBEC3 Family.

  Frontiers in microbiology 20120101

• Analysis of 5'-mononucleotides in infant formula and adult/pediatric nutritional formula by liquid chromatography: First Action 2011.20.

  Journal of AOAC International 20120101

• HILIC-MS/MS method for the quantitation of nucleotides in infant formula and adult nutritional formula: First Action 2011.21.

  Journal of AOAC International 20120101

• Antiviral activity of nucleoside analogues against norovirus.

  Antiviral therapy 20120101

• Retroelements versus APOBEC3 family members: No great escape from the magnificent seven.

  Frontiers in microbiology 20120101

• Combinatorial treatment of DNA and chromatin-modifying drugs cause cell death in human and canine osteosarcoma cell lines.

  PloS one 20120101

• Random mutagenesis MAPPIT analysis identifies binding sites for Vif and Gag in both cytidine deaminase domains of Apobec3G.

  PloS one 20120101

• Genetic polymorphisms of drug metabolizing enzymes and transporters: the long way from bench to bedside.

  Current topics in medicinal chemistry 20120101

• A-to-I editing of protein coding and noncoding RNAs.

  Critical reviews in biochemistry and molecular biology 20120101

• Comparative kinetic analysis of glycerol 3-phosphate cytidylyltransferase from Enterococcus faecalis and Listeria monocytogenes.

  Medical science monitor : international medical journal of experimental and clinical research 20120101

• T-cell differentiation factor CBF-β regulates HIV-1 Vif-mediated evasion of host restriction.

  Nature 20111221

• Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection.

  Nature 20111221

• Association of AICD and Fe65 with Hirano bodies reduces transcriptional activation and initiation of apoptosis.

  Neurobiology of aging 20111201

• Cytostatic activity of the duplex drug linking 2'-deoxy-5-fluorouridine (5FdU) with 3'-C-ethynylcytidine (ECyd) against gastric adenocarcinoma cell lines.

  Investigational new drugs 20111201

• AID dysregulation in lupus-prone MRL/Fas(lpr/lpr) mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: modulation by HoxC4.

  Autoimmunity 20111201

• QSAR models for phosphoramidate prodrugs of 2'-methylcytidine as inhibitors of hepatitis C virus based on PSO boosting.

  Chemical biology & drug design 20111201

• Early B blasts acquire a capacity for Ig class switch recombination that is lost as they become plasmablasts.

  European journal of immunology 20111201

• DNA methylation at tobacco telomeric sequences.

  Plant molecular biology 20111201

• Association of cytidine deaminase and xeroderma pigmentosum group D polymorphisms with response, toxicity, and survival in cisplatin/gemcitabine-treated advanced non-small cell lung cancer patients.

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20111201

• Mismatch-mediated error prone repair at the immunoglobulin genes.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20111201

• Genome instability and transcription elongation impairment in human cells depleted of THO/TREX.

  PLoS genetics 20111201

• Identification of a genomic reservoir for new TRIM genes in primate genomes.

  PLoS genetics 20111201

• The therapeutic approaches for hepatitis C virus: protease inhibitors and polymerase inhibitors.

  Gut and liver 20111201

• The establishment of early B cell tolerance in humans: lessons from primary immunodeficiency diseases.

  Annals of the New York Academy of Sciences 20111201

• Autosomal recessive dilated cardiomyopathy due to DOLK mutations results from abnormal dystroglycan O-mannosylation.

  PLoS genetics 20111201

• Genetic architecture of HIV-1 genes circulating in north India & their functional implications.

  The Indian journal of medical research 20111201

• The serotonin-6 receptor as a novel therapeutic target.

  Experimental neurobiology 20111201

• A novel method for quantification of gemcitabine and its metabolites 2',2'-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with (19)F NMR spectroscopy.

  Cancer chemotherapy and pharmacology 20111101

• Hypomethylating drugs efficiently decrease cytosine methylation in telomeric DNA and activate telomerase without affecting telomere lengths in tobacco cells.

  Plant molecular biology 20111101

• Bile acid-induced expression of activation-induced cytidine deaminase during the development of Barrett's oesophageal adenocarcinoma.

  Carcinogenesis 20111101

• Epigenetic reprogramming: is deamination key to active DNA demethylation?

  Reproduction (Cambridge, England) 20111101

• A prophylactic effect of an oligodeoxynucleotide containing a cytidine-guanosine motif against Japanese cedar pollen-induced T-helper type 2 allergic response.

  The Journal of asthma : official journal of the Association for the Care of Asthma 20111101

• Complexes between nuclear factor-κB p65 and signal transducer and activator of transcription 3 are key actors in inducing activation-induced cytidine deaminase expression and immunoglobulin A production in CD40L plus interleukin-10-treated human blood B cells.

  Clinical and experimental immunology 20111101

• APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis.

  The Journal of clinical investigation 20111101

• A positively selected APOBEC3H haplotype is associated with natural resistance to HIV-1 infection.

  Evolution; international journal of organic evolution 20111101

• Large-scale DNA editing of retrotransposons accelerates mammalian genome evolution.

  Nature communications 20111101

• Signatures of environmental genetic adaptation pinpoint pathogens as the main selective pressure through human evolution.

  PLoS genetics 20111101

• Crystallization and preliminary X-ray diffraction analysis of an archaeal tRNA-modification enzyme, TiaS, complexed with tRNA(Ile2) and ATP.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20111101

• The molecular biology of feline immunodeficiency virus (FIV).

  Viruses 20111101

• Reactions of beta-propiolactone with nucleobase analogues, nucleosides, and peptides: implications for the inactivation of viruses.

  The Journal of biological chemistry 20111021

• Endogenous APOBEC3B restricts LINE-1 retrotransposition in transformed cells and human embryonic stem cells.

  The Journal of biological chemistry 20111021

• Biogenesis of 2-agmatinylcytidine catalyzed by the dual protein and RNA kinase TiaS.

  Nature structural & molecular biology 20111016

• Structural basis of tRNA agmatinylation essential for AUA codon decoding.

  Nature structural & molecular biology 20111016

• The role of BST2/tetherin in feline retrovirus infection.

  Veterinary immunology and immunopathology 20111015

• Selective derivatization of cytosine and methylcytosine moieties with 2-bromoacetophenone for submicrogram DNA methylation analysis by reversed phase HPLC with spectrofluorimetric detection.

  Analytical chemistry 20111015

• Towards multimodal HPLC separations on humic acid-bonded aminopropyl silica: RPLC and LEC behavior.

  Talanta 20111015

• A novel role for activation-induced cytidine deaminase: central B-cell tolerance.

  Cell cycle (Georgetown, Tex.) 20111015

• Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites.

  The Journal of biological chemistry 20111014

• New N-acetyltransferase fold in the structure and mechanism of the phosphonate biosynthetic enzyme FrbF.

  The Journal of biological chemistry 20111014

• Electrogenerated chemiluminescence of triazole-modified deoxycytidine analogues in N,N-dimethylformamide.

  Physical chemistry chemical physics : PCCP 20111014

• Factors predicting occurrence and prognosis of hepatitis-B-virus-related hepatocellular carcinoma.

  World journal of gastroenterology 20111014

• Protein glycoengineering enabled by the versatile synthesis of aminooxy glycans and the genetically encoded aldehyde tag.

  Journal of the American Chemical Society 20111012

• Differential virus restriction patterns of rhesus macaque and human APOBEC3A: implications for lentivirus evolution.

  Virology 20111010

• Characterization of anti-HIV activity mediated by R88-APOBEC3G mutant fusion proteins in CD4+ T cells, peripheral blood mononuclear cells, and macrophages.

  Human gene therapy 20111001

• Strategies for selection marker-free swine transgenesis using the Sleeping Beauty transposon system.

  Transgenic research 20111001

• The state-of-the-art determination of urinary nucleosides using chromatographic techniques 'hyphenated' with advanced bioinformatic methods.

  Analytical and bioanalytical chemistry 20111001

• The R5 to X4 coreceptor switch: a dead-end path, or a strategic maneuver? Lessons from a game theoretic analysis.

  Bulletin of mathematical biology 20111001

• Deficiency of X-linked inverted duplicates with male-biased expression and the underlying evolutionary mechanisms in the Drosophila genome.

  Molecular biology and evolution 20111001

• AID expression is correlated with Bcr-Abl expression in CML-LBC and can be down-regulated by As2O3 and/or imatinib.

  Leukemia research 20111001

• RNA editing restores critical domains of a group I intron in fern mitochondria.

  Current genetics 20111001

• An anti-HIV-1 compound that increases steady-state expression of apoplipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G.

  International journal of molecular medicine 20111001

• Core-APOBEC3C chimerical protein inhibits hepatitis B virus replication.

  Journal of biochemistry 20111001

• A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells.

  Annals of the rheumatic diseases 20111001

• Deep sequencing of microRNA precursors reveals extensive 3' end modification.

  RNA (New York, N.Y.) 20111001

• The antiviral factor APOBEC3G enhances the recognition of HIV-infected primary T cells by natural killer cells.

  Nature immunology 20111001

• Comparative analysis of involvement of UGT1 and UGT2 splice variants of UDP-galactose transporter in glycosylation of macromolecules in MDCK and CHO cell lines.

  Glycoconjugate journal 20111001

• Evaluation of F-18-labeled 5-iodocytidine (18F-FIAC) as a new potential positron emission tomography probe for herpes simplex virus type 1 thymidine kinase imaging.

  Nuclear medicine and biology 20111001

• Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response.

  PLoS pathogens 20111001

• Toll-like receptor 7 controls the anti-retroviral germinal center response.

  PLoS pathogens 20111001

• Prior virus exposure alters the long-term landscape of viral replication during feline lentiviral infection.

  Viruses 20111001

• Cellular restriction factors of feline immunodeficiency virus.

  Viruses 20111001

• Intracellular detection of differential APOBEC3G, TRIM5alpha, and LEDGF/p75 protein expression in peripheral blood by flow cytometry.

  Journal of immunological methods 20110930

• Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes.

  Cell 20110930

• Damage control: how HIV survives the editor APOBEC3G.

  Nature immunology 20110920

• Nucleobase transport by human equilibrative nucleoside transporter 1 (hENT1).

  The Journal of biological chemistry 20110916

• DNA demethylation dynamics.

  Cell 20110916

• The mismatch repair pathway functions normally at a non-AID target in germinal center B cells.

  Blood 20110915

• Identification and quantification of nucleosides and nucleobases in Geosaurus and Leech by hydrophilic-interaction chromatography.

  Talanta 20110915

• Separation of mutational and transcriptional enhancers in Ig genes.

  Journal of immunology (Baltimore, Md. : 1950) 20110915

• Direct evidence that RNA inhibits APOBEC3G ssDNA cytidine deaminase activity.

  Biochemical and biophysical research communications 20110909

• Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast.

  DNA repair 20110905

• Human hepatic cancer stem cells are characterized by common stemness traits and diverse oncogenic pathways.

  Hepatology (Baltimore, Md.) 20110902

• Deaminase activity on single-stranded DNA (ssDNA) occurs in vitro when APOBEC3G cytidine deaminase forms homotetramers and higher-order complexes.

  The Journal of biological chemistry 20110902

• Activation-induced cytidine deaminase structure and functions: a species comparative view.

  Developmental and comparative immunology 20110901

• Effect of transition metal ions on the fluorescence and Taq-catalyzed polymerase chain reaction of tricyclic cytidine analogs.

  Analytical biochemistry 20110901

• Expression of IgA class switching gene in tonsillar mononuclear cells in patients with IgA nephropathy.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110901

• Rapid cell division contributes to efficient induction of A/T mutations during Ig gene hypermutation.

  Molecular immunology 20110901

• CDP-choline and its endogenous metabolites, cytidine and choline, promote the nerve regeneration and improve the functional recovery of injured rat sciatic nerves.

  Neurological research 20110901

• AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected].

  Journal of immunology (Baltimore, Md. : 1950) 20110901

• Roles of the Polycomb group proteins in stem cells and cancer.

  Cell death & disease 20110901

• Meningococcal factor H binding proteins in epidemic strains from Africa: implications for vaccine development.

  PLoS neglected tropical diseases 20110901

• APOBEC3A is a specific inhibitor of the early phases of HIV-1 infection in myeloid cells.

  PLoS pathogens 20110901

• Expression of activation-induced cytidine deaminase in ulcerative colitis-associated carcinogenesis.

  Histopathology 20110901

• Insights into the B cell specific process of immunoglobulin class switch recombination.

  Immunology letters 20110830

• [The cutting-edge of medicine; inflammation and development of gastrointestinal cancers].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20110810

• Multiple conformations of the cytidine repressor DNA-binding domain coalesce to one upon recognition of a specific DNA surface.

  Biochemistry 20110809

• Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni.

  Nature communications 20110809

• Duplex and triplex formation of mixed pyrimidine oligonucleotides with stacking of phenyl-triazole moieties in the major groove.

  The Journal of organic chemistry 20110805

• High levels of activation-induced cytidine deaminase expression in adult T-cell leukaemia/lymphoma.

  The British journal of dermatology 20110801

• Hepatitis C virus therapeutics: editing enzymes promising therapeutic targets?

  Hepatology (Baltimore, Md.) 20110801

• Effect of HIV-1 Vif variability on progression to pediatric AIDS and its association with APOBEC3G and CUL5 polymorphisms.

  Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20110801

• Antiviral activity and mode of action of TMC647078, a novel nucleoside inhibitor of the hepatitis C virus NS5B polymerase.

  Antimicrobial agents and chemotherapy 20110801

• Delineation of the molecular mechanisms of nucleoside recognition by cytidine deaminase through virtual screening.

  ChemMedChem 20110801

• Comparison of in vitro metabolic conversion of capecitabine to 5-FU in rats, mice, monkeys and humans--toxicological implications.

  The Journal of toxicological sciences 20110801

• [Role of inflammation in the development of gastrointestinal cancers].

  Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20110801

• Impact of the autophagy machinery on hepatitis C virus infection.

  Viruses 20110801

• Expression profiling of non-aflatoxigenic Aspergillus parasiticus mutants obtained by 5-azacytosine treatment or serial mycelial transfer.

  Toxins 20110801

• Epigenetic regulation of prostate cancer.

  Clinical epigenetics 20110801

• Phosphorylation directly regulates the intrinsic DNA cytidine deaminase activity of activation-induced deaminase and APOBEC3G protein.

  The Journal of biological chemistry 20110729

• HIV-1 replication in monocyte-derived dendritic cells is stimulated by melarsoprol, one of the main drugs against human African trypanosomiasis.

  Journal of molecular biology 20110729

• Multifaceted counter-APOBEC3G mechanisms employed by HIV-1 Vif.

  Journal of molecular biology 20110729

• Benchmarking AMBER force fields for RNA: comparisons to NMR spectra for single-stranded r(GACC) are improved by revised χ torsions.

  The journal of physical chemistry. B 20110728

• Analysis of a single-stranded DNA-scanning process in which activation-induced deoxycytidine deaminase (AID) deaminates C to U haphazardly and inefficiently to ensure mutational diversity.

  The Journal of biological chemistry 20110715

• iNOS potentiates mouse Ig isotype switching through AID expression.

  Biochemical and biophysical research communications 20110708

• Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair.

  Cell 20110708

• Biomarkers and pharmacogenetics in pancreatic cancer. Highlights from the '2011 ASCO Annual Meeting'. Chicago, IL, USA; June 3-7, 2011.

  JOP : Journal of the pancreas 20110708

• Low-temperature NMR studies on inosine wobble base pairs.

  The journal of physical chemistry. B 20110707

• Aberrant expression and mutation-inducing activity of AID in human lung cancer.

  Annals of surgical oncology 20110701

• Activation-induced cytidine deaminase catalytic domain as a target to eliminate pathogenic autoantibodies.

  Arthritis and rheumatism 20110701

• Inhibition of the catalytic function of activation-induced cytidine deaminase promotes apoptosis of germinal center B cells in BXD2 mice.

  Arthritis and rheumatism 20110701

• Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.

  Journal of structural and functional genomics 20110701

• Cyclopentenyl cytosine induces senescence in breast cancer cells through the nucleolar stress response and activation of p53.

  Molecular pharmacology 20110701

• A selective adenosine sensor derived from a triplex DNA aptamer.

  Analytical and bioanalytical chemistry 20110701

• Synovial fibroblasts promote immunoglobulin class switching by a mechanism involving BAFF.

  European journal of immunology 20110701

• Fluorescent labeling of tRNA dihydrouridine residues: Mechanism and distribution.

  RNA (New York, N.Y.) 20110701

• San-Huang-Xie-Xin-Tang extract suppresses hepatitis C virus replication and virus-induced cyclooxygenase-2 expression.

  Journal of viral hepatitis 20110701

• HPLC-MS/MS method for the determination of cytarabine in human plasma.

  Bioanalysis 20110701

• Systems-biology approaches to discover anti-viral effectors of the human innate immune response.

  Viruses 20110701

• Innate antiviral response: role in HIV-1 infection.

  Viruses 20110701

• Pyrimidine pool imbalance induced by BLM helicase deficiency contributes to genetic instability in Bloom syndrome.

  Nature communications 20110628

• The pentatricopeptide repeat protein OTP87 is essential for RNA editing of nad7 and atp1 transcripts in Arabidopsis mitochondria.

  The Journal of biological chemistry 20110617

• Analysis of global DNA methylation by hydrophilic interaction ultra high-pressure liquid chromatography tandem mass spectrometry.

  Analytical biochemistry 20110615

• C5-DNA methyltransferase inhibitors: from screening to effects on zebrafish embryo development.

  Chembiochem : a European journal of chemical biology 20110614

• Functional analysis of the two cytidine deaminase domains in APOBEC3G.

  Virology 20110605

• ATP chemosensitivity testing of new antitumor duplex drugs linking 3`-C-ethynylycytidine (ECyd) and 2´-deoxy-5-fluorouridine (5-FdU) in comparison to standard cytostatica and combinations thereof.

  Investigational new drugs 20110601

• Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models.

  Investigational new drugs 20110601

• Tetherin and its viral antagonists.

  Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20110601

• Immunization with cationized BSA inhibits progression of disease in ApoBec-1/LDL receptor deficient mice with manifest atherosclerosis.

  Immunobiology 20110601

• Local class switching in nonallergic rhinitis.

  Current opinion in otolaryngology & head and neck surgery 20110601

• Molecular mechanism of immunoglobulin V-region diversification regulated by transcription and RNA metabolism in antigen-driven B cells.

  Scandinavian journal of immunology 20110601

• AID and partners: for better and (not) for worse.

  Current opinion in immunology 20110601

• Insights into mutagenesis using Escherichia coli chromosomal lacZ strains that enable detection of a wide spectrum of mutational events.

  Genetics 20110601

• Synthesis, characterization and cytotoxic properties of platinum(II) complexes containing the nucleosides adenosine and cytidine.

  Journal of inorganic biochemistry 20110601

• Transmembrane activator and CAML interactor (TACI) haploinsufficiency results in B-cell dysfunction in patients with Smith-Magenis syndrome.

  The Journal of allergy and clinical immunology 20110601

• A domain of the actin binding protein Abp140 is the yeast methyltransferase responsible for 3-methylcytidine modification in the tRNA anti-codon loop.

  RNA (New York, N.Y.) 20110601

• Actin-binding protein ABP140 is a methyltransferase for 3-methylcytidine at position 32 of tRNAs in Saccharomyces cerevisiae.

  RNA (New York, N.Y.) 20110601

• N⁴-[Alkyl-(hydroxyphosphono)phosphonate]-cytidine-new drugs covalently linking antimetabolites (5-FdU, araU or AZT) with bone-targeting bisphosphonates (alendronate or pamidronate).

  Bioorganic & medicinal chemistry 20110601

• Aberrant activation-induced cytidine deaminase expression is associated with mucosal intestinalization in the early stage of gastric cancer.

  Virchows Archiv : an international journal of pathology 20110601

• Educational paper: primary antibody deficiencies.

  European journal of pediatrics 20110601

• The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells.

  Nature immunology 20110601

• High-resolution analysis of parent-of-origin allelic expression in the Arabidopsis Endosperm.

  PLoS genetics 20110601

• The N-terminus of the RNA polymerase from infectious pancreatic necrosis virus is the determinant of genome attachment.

  PLoS pathogens 20110601

• Trimethylsilyl trifluoromethanesulfonate-promoted reductive 2'-O-arylmethylation of ribonucleoside derivatives.

  Nucleosides, nucleotides & nucleic acids 20110601

• [Mechanisms for inhibition of retrovirus replication by APOBEC3 family].

  Uirusu 20110601

• Kainic Acid-induced neurotoxicity: targeting glial responses and glia-derived cytokines.

  Current neuropharmacology 20110601

• A single amino acid limits the substrate specificity of Thermus thermophilus uridine-cytidine kinase to cytidine.

  Biochemistry 20110531

• Methylation stabilizes the imino tautomer of dAMP and amino tautomer of dCMP in solution.

  The journal of physical chemistry. B 20110519

• Dynamics and couplings of N-H stretching excitations of guanosine-cytidine base pairs in solution.

  The journal of physical chemistry. B 20110512

• Correlations of six related pyrimidine metabolites and diabetic retinopathy in Chinese type 2 diabetic patients.

  Clinica chimica acta; international journal of clinical chemistry 20110512

• Molecular recognition of the antiretroviral drug abacavir: towards the development of a novel carbazole-based fluorosensor.

  Journal of fluorescence 20110501

• APOBEC3G: a double agent in defense.

  Trends in biochemical sciences 20110501

• Crystal structure determination and dynamic studies of Mycobacterium tuberculosis Cytidine deaminase in complex with products.

  Archives of biochemistry and biophysics 20110501

• Fluorescent and colorimetric chemosensors for detection of nucleotides, FAD and NADH: highlighted research during 2004-2010.

  Chemical Society reviews 20110501

• Life without the essential bacterial tRNA Ile2-lysidine synthetase TilS: a case of tRNA gene recruitment in Bacillus subtilis.

  Molecular microbiology 20110501

• APOBEC3A can activate the DNA damage response and cause cell-cycle arrest.

  EMBO reports 20110501

• Translocation of an antibody transgene requires AID and occurs by interchromosomal switching to all switch regions except the mu switch region.

  European journal of immunology 20110501

• Complex regulation and function of activation-induced cytidine deaminase.

  Trends in immunology 20110501

• SIV Nef proteins recruit the AP-2 complex to antagonize Tetherin and facilitate virion release.

  PLoS pathogens 20110501

• Host alternation is necessary to maintain the genome stability of rift valley fever virus.

  PLoS neglected tropical diseases 20110501

• Antiviral inhibition of enveloped virus release by tetherin/BST-2: action and counteraction.

  Viruses 20110501

• Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain.

  Cell 20110429

• Sense transcription through the S region is essential for immunoglobulin class switch recombination.

  The EMBO journal 20110420

• Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease.

  The Journal of biological chemistry 20110408

• Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity.

  The EMBO journal 20110406

• Cellular pharmacology of multi- and duplex drugs consisting of ethynylcytidine and 5-fluoro-2'-deoxyuridine.

  Investigational new drugs 20110401

• Deoxyuridine analog nucleotides in deoxycytidine analog treatment: secondary active metabolites?

  Fundamental & clinical pharmacology 20110401

• Human biodistribution and radiation dosimetry of novel PET probes targeting the deoxyribonucleoside salvage pathway.

  European journal of nuclear medicine and molecular imaging 20110401

• AID: a riddle wrapped in a mystery inside an enigma.

  Immunologic research 20110401

• AID expression during B-cell development: searching for answers.

  Immunologic research 20110401

• FNC, a novel nucleoside analogue inhibits cell proliferation and tumor growth in a variety of human cancer cells.

  Biochemical pharmacology 20110401

• Activation-induced deaminase-deficient MRL/lpr mice secrete high levels of protective antibodies against lupus nephritis.

  Arthritis and rheumatism 20110401

• E47 retroviral rescue of intrinsic B-cell defects in senescent mice.

  Aging cell 20110401

• Targeting of AID-mediated sequence diversification to immunoglobulin genes.

  Current opinion in immunology 20110401

• Deoxyribonucleotide metabolism in cycling and resting human fibroblasts with a missense mutation in p53R2, a subunit of ribonucleotide reductase.

  The Journal of biological chemistry 20110401

• Intensity of deoxycytidine deamination of HIV-1 proviral DNA by the retroviral restriction factor APOBEC3G is mediated by the noncatalytic domain.

  The Journal of biological chemistry 20110401

• A polymorphism in the cytidine deaminase promoter predicts severe capecitabine-induced hand-foot syndrome.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20110401

• PNA containing isocytidine nucleobase: synthesis and recognition of double helical RNA.

  Bioorganic & medicinal chemistry letters 20110401

• Enzymatic activity of the soybean ecto-apyrase GS52 is essential for stimulation of nodulation.

  Plant physiology 20110401

• Mutation Vif-22H, which allows HIV-1 to use the APOBEC3G hypermutation to develop resistance, could appear more quickly in certain non-B variants.

  The Journal of antimicrobial chemotherapy 20110401

• Repression of porcine endogenous retrovirus infection by human APOBEC3 proteins.

  Biochemical and biophysical research communications 20110401

• Simultaneous determination of 5'-monophosphate nucleotides in infant formulas by HPLC-MS.

  Journal of chromatographic science 20110401

• Innate immunity and HIV-1 infection.

  Advances in dental research 20110401

• The relationship between hypothesis and experiment in unveiling the mechanisms of antibody gene diversification.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110401

• Host apolipoprotein B messenger RNA-editing enzyme catalytic polypeptide-like 3G is an innate defensive factor and drug target against hepatitis C virus.

  Hepatology (Baltimore, Md.) 20110401

• Reversing B cell aging.

  Aging 20110401

• D-myo-inositol-3-phosphate affects phosphatidylinositol-mediated endomembrane function in Arabidopsis and is essential for auxin-regulated embryogenesis.

  The Plant cell 20110401

• Variability in transport and biotransformation of cytarabine is associated with its toxicity in peripheral blood mononuclear cells.

  Pharmacogenomics 20110401

• Profile of nucleotides and nucleosides in Taiwanese human milk.

  Pediatrics and neonatology 20110401

• Clinical management of HIV drug resistance.

  Viruses 20110401

• Heat shock protein 70 inhibits HIV-1 Vif-mediated ubiquitination and degradation of APOBEC3G.

  The Journal of biological chemistry 20110325

• CDP-choline-induced contractions in the mouse gastric fundus through purinoceptors and Rho/Rho-kinase signalling.

  Life sciences 20110314

• Development of modified nucleosides that have supremely high anti-HIV activity and low toxicity and prevent the emergence of resistant HIV mutants.

  Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110311

• The nerve growth factor reduces APOBEC3G synthesis and enhances HIV-1 transcription and replication in human primary macrophages.

  Blood 20110310

• 5-azacytidine, a chemotherapeutic drug, induces TRAIL-mediated apoptosis in mouse thymocytes in vivo.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20110301

• MicroRNA let-7 suppresses nasopharyngeal carcinoma cells proliferation through downregulating c-Myc expression.

  Journal of cancer research and clinical oncology 20110301

• Biophysical characterization of recombinant HIV-1 subtype C virus infectivity factor.

  Amino acids 20110301

• Hypermethylation of specific microRNA genes in MLL-rearranged infant acute lymphoblastic leukemia: major matters at a micro scale.

  Leukemia 20110301

• Macrophage-derived BAFF induces AID expression through the p38MAPK/CREB and JNK/AP-1 pathways.

  Journal of leukocyte biology 20110301

• Analysis of reptilian APOBEC1 suggests that RNA editing may not be its ancestral function.

  Molecular biology and evolution 20110301

• Disrupted plasma membrane localization of equilibrative nucleoside transporter 2 in the chemoresistance of human pancreatic cells to gemcitabine (dFdCyd).

  Cancer science 20110301

• Plasmalogen synthesis is regulated via alkyl-dihydroxyacetonephosphate-synthase by amyloid precursor protein processing and is affected in Alzheimer's disease.

  Journal of neurochemistry 20110301

• Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense.

  Nature immunology 20110301

• Equilibrative nucleoside transporter 1 genotype, cytidine deaminase activity and age predict gemcitabine plasma clearance in patients with solid tumours.

  British journal of clinical pharmacology 20110301

• p21 is dispensable for AID-mediated class switch recombination and mutagenesis of immunoglobulin genes during somatic hypermutation.

  Molecular immunology 20110301

• The pharmacological advantage of prolonged dose rate gemcitabine is restricted to patients with variant alleles of cytidine deaminase c.79A>C.

  Asia-Pacific journal of clinical oncology 20110301

• Phospholipase activities in clinical and environmental isolates of Acanthamoeba.

  The Korean journal of parasitology 20110301

• Limited dCTP availability accounts for mitochondrial DNA depletion in mitochondrial neurogastrointestinal encephalomyopathy (MNGIE).

  PLoS genetics 20110301

• New insights into perinatal depression: pathogenesis and treatment during pregnancy and postpartum.

  Dialogues in clinical neuroscience 20110301

• AICDA expression in BCR/ABL1-positive acute lymphoblastic leukaemia is associated with a peculiar gene expression profile.

  British journal of haematology 20110301

• [Simultaneous determination of seven nucleosides and nucleobases in aqueous extracts of Fritillaria taipaiensis by HPLC-DAD].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110301

• [Research methods of anti-HIV-1 inhibitors targeting at Vif-APOBEC3G axis].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110301

• Paradoxical interplay of viral and cellular functions.

  Viruses 20110301

• The human mitochondrial tRNAMet: structure/function relationship of a unique modification in the decoding of unconventional codons.

  Journal of molecular biology 20110218

• Integrating pharmacogenetics into gemcitabine dosing--time for a change?

  Nature reviews. Clinical oncology 20110208

• Photoelectron and computational studies of the copper-nucleoside anionic complexes, Cu(-)(cytidine) and Cu(-)(uridine).

  The Journal of chemical physics 20110207

• Recognition of transcription termination signal by the nuclear polyadenylated RNA-binding (NAB) 3 protein.

  The Journal of biological chemistry 20110204

• Atomic force microscopy studies provide direct evidence for dimerization of the HIV restriction factor APOBEC3G.

  The Journal of biological chemistry 20110204

• The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates.

  Cell 20110204

• Unprecedented C-selective interstrand cross-linking through in situ oxidation of furan-modified oligodeoxynucleotides.

  Journal of the American Chemical Society 20110202

• Plasma pharmacokinetics and oral bioavailability of the 3,4,5,6-tetrahydrouridine (THU) prodrug, triacetyl-THU (taTHU), in mice.

  Cancer chemotherapy and pharmacology 20110201

• Loci polymorphisms of the APOBEC3G gene in HIV type 1-infected Brazilians.

  AIDS research and human retroviruses 20110201

• APOBEC2, a selective inhibitor of TGFβ signaling, regulates left-right axis specification during early embryogenesis.

  Developmental biology 20110201

• Targets of somatic hypermutation within immunoglobulin light chain genes in zebrafish.

  Immunology 20110201

• Systems analysis of small signaling modules relevant to eight human diseases.

  Annals of biomedical engineering 20110201

• Epigenetic regulation of gene expression as an anticancer drug target.

  Current cancer drug targets 20110201

• The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA.

  Nature immunology 20110201

• Functional and structural analyses of N-acylsulfonamide-linked dinucleoside inhibitors of RNase A.

  The FEBS journal 20110201

• Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA-editing targets in transcript 3' UTRs.

  Nature structural & molecular biology 20110201

• The dependence of Ig class-switching on the nuclear export sequence of AID likely reflects interaction with factors additional to Crm1 exportin.

  European journal of immunology 20110201

• Activation-induced cytidine deaminase and aberrant germinal center selection in the development of humoral autoimmunities.

  The American journal of pathology 20110201

• [Pharmacogenomic research for avoiding adverse reactions by anti-cancer drugs].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110201

• Hsp90 can accommodate the simultaneous binding of the FKBP52 and HOP proteins.

  Oncotarget 20110201

• AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants.

  PLoS genetics 20110201

• The inside out of lentiviral vectors.

  Viruses 20110201

• NFAT and IRF proteins regulate transcription of the anti-HIV gene, APOBEC3G.

  The Journal of biological chemistry 20110128

• Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells.

  Molecular cell 20110121

• Highly sensitive electrochemiluminescent biosensor for adenosine based on structure-switching of aptamer.

  Analytica chimica acta 20110117

• Controlled synthesis of Pt nanoparticles array through electroreduction of cisplatin bound at nucleobases terminated surface and application into H2O2 sensing.

  Biosensors & bioelectronics 20110115

• Yeast Sen1 helicase protects the genome from transcription-associated instability.

  Molecular cell 20110107

• The role of FKBP5 in cancer aetiology and chemoresistance.

  British journal of cancer 20110104

• Heat shock protein 70 (Hsp70)-stimulated deoxycytidine deaminases from a human lymphoma cell but not the activation-induced cytidine deaminase (AID) from Ramos 6.4 human Burkitt's lymphoma cells.

  Cell stress & chaperones 20110101

• A novel N-hydroxy-N'-aminoguanidine derivative inhibits ribonucleotide reductase activity: Effects in human HL-60 promyelocytic leukemia cells and synergism with arabinofuranosylcytosine (Ara-C).

  Biochemical pharmacology 20110101

• Involvement of activation-induced cytidine deaminase in the development of colitis-associated colorectal cancers.

  Journal of gastroenterology 20110101

• Mediators and dynamics of DNA methylation.

  Wiley interdisciplinary reviews. Systems biology and medicine 20110101

• Altered spectrum of somatic hypermutation in common variable immunodeficiency disease characteristic of defective repair of mutations.

  Immunogenetics 20110101

• Molecular mechanisms of nucleoside recycling in the brain.

  The international journal of biochemistry & cell biology 20110101

• Activation of AID by human T-cell leukemia virus Tax oncoprotein and the possible role of its constitutive expression in ATL genesis.

  Carcinogenesis 20110101

• Target RNA-directed tailing and trimming purifies the sorting of endo-siRNAs between the two Drosophila Argonaute proteins.

  RNA (New York, N.Y.) 20110101

• Ectopic expression of activation-induced cytidine deaminase caused by epigenetics modification.

  Oncology reports 20110101

• Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes.

  Nature immunology 20110101

• Activation-induced cytidine deaminase mRNA levels in chronic lymphocytic leukemia.

  Leukemia & lymphoma 20110101

• Imaging lipid synthesis in hepatocellular carcinoma with [methyl-11c]choline: correlation with in vivo metabolic studies.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110101

• Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions.

  Nature immunology 20110101

• Novel and emerging drugs for acute myeloid leukemia: pharmacology and therapeutic activity.

  Current medicinal chemistry 20110101

• MicroRNAs and Multiple Sclerosis.

  Autoimmune diseases 20110101

• Review: magnetic resonance spectroscopy studies of pediatric major depressive disorder.

  Depression research and treatment 20110101

• The cellular source for APOBEC3G's incorporation into HIV-1.

  Retrovirology 20110101

• Salivary glands of primary Sjögren's syndrome patients express factors vital for plasma cell survival.

  Arthritis research & therapy 20110101

• Mechanisms that promote and suppress chromosomal translocations in lymphocytes.

  Annual review of immunology 20110101

• Identification of novel DNA methylation inhibitors via a two-component reporter gene system.

  Journal of biomedical science 20110101

• A CMP-N-acetylneuraminic acid synthetase purified from a marine bacterium, Photobacterium leiognathi JT-SHIZ-145.

  Bioscience, biotechnology, and biochemistry 20110101

• Cardiogenol C can induce Mouse Hair Bulge Progenitor Cells to Transdifferentiate into Cardiomyocyte-like Cells.

  Proteome science 20110101

• Clinical monitoring and correlates of nephropathy in SIV-infected macaques during high-dose antiretroviral therapy.

  AIDS research and therapy 20110101

• A novel modular antigen delivery system for immuno targeting of human 6-sulfo LacNAc-positive blood dendritic cells (SlanDCs).

  PloS one 20110101

• Complete genome sequence of a serotype 11A, ST62 Streptococcus pneumoniae invasive isolate.

  BMC microbiology 20110101

• An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody.

  mBio 20110101

• Inaccurate DNA synthesis in cell extracts of yeast producing active human DNA polymerase iota.

  PloS one 20110101

• Inhibition of histone deacetylases 1 and 6 enhances cytarabine-induced apoptosis in pediatric acute myeloid leukemia cells.

  PloS one 20110101

• Pyrimidine salvage pathway in Mycobacterium tuberculosis.

  Current medicinal chemistry 20110101

• Identifying mRNA editing deaminase targets by RNA-Seq.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Mouse and other rodent models of C to U RNA editing.

  Methods in molecular biology (Clifton, N.J.) 20110101

• In vivo analysis of RNA editing in plastids.

  Methods in molecular biology (Clifton, N.J.) 20110101

• A high-throughput assay for DNA deaminases.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Biochemical fractionation and purification of high-molecular-mass APOBEC3G complexes.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Newly engineered magnetic erythrocytes for sustained and targeted delivery of anti-cancer therapeutic compounds.

  PloS one 20110101

• Enhanced uridine bioavailability following administration of a triacetyluridine-rich nutritional supplement.

  PloS one 20110101

• Uracil DNA N-glycosylase promotes assembly of human centromere protein A.

  PloS one 20110101

• Metabolic network of nucleosides in the brain.

  Current topics in medicinal chemistry 20110101

• 5'UTR variants of ribosomal protein S19 transcript determine translational efficiency: implications for Diamond-Blackfan anemia and tissue variability.

  PloS one 20110101

• Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureus, Staphylococcus epidermidis and human cells.

  Genome biology 20110101

• Unusual nucleotide content of Rubella virus genome as a consequence of biased RNA-editing: comparison with Alphaviruses.

  International journal of bioinformatics research and applications 20110101

• Visualization of spatiotemporal energy dynamics of hippocampal neurons by mass spectrometry during a kainate-induced seizure.

  PloS one 20110101

• Computational detection and functional analysis of human tissue-specific A-to-I RNA editing.

  PloS one 20110101

• Continuous and low-energy 125I seed irradiation changes DNA methyltransferases expression patterns and inhibits pancreatic cancer tumor growth.

  Journal of experimental & clinical cancer research : CR 20110101

• Branched RNA: A New Architecture for RNA Interference.

  Journal of nucleic acids 20110101

• Efficient silencing of gene expression by an ASON-bulge-DNAzyme complex.

  PloS one 20110101

• A model for the evolution of nucleotide polymerase directionality.

  PloS one 20110101

• Classical Mus musculus Igκ enhancers support transcription but not high level somatic hypermutation from a V-lambda promoter in chicken DT40 cells.

  PloS one 20110101

• Epigenetic regulation of cancer-associated genes in ovarian cancer.

  International journal of molecular sciences 20110101

• Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition.

  BMC biochemistry 20110101

• The four Zn fingers of MBNL1 provide a flexible platform for recognition of its RNA binding elements.

  BMC molecular biology 20110101

• IP6K gene identification in plant genomes by tag searching.

  BMC proceedings 20110101

• MetaPath: identifying differentially abundant metabolic pathways in metagenomic datasets.

  BMC proceedings 20110101

• Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference.

  International journal of Alzheimer's disease 20110101

• UMP/CMPK is not the critical enzyme in the metabolism of pyrimidine ribonucleotide and activation of deoxycytidine analogs in human RKO cells.

  PloS one 20110101

• Modeling initiation of Ewing sarcoma in human neural crest cells.

  PloS one 20110101

• Mutator effects and mutation signatures of editing deaminases produced in bacteria and yeast.

  Biochemistry. Biokhimiia 20110101

• The evolution of adaptive immunity in vertebrates.

  Advances in immunology 20110101

• DNA methyltransferase controls stem cell aging by regulating BMI1 and EZH2 through microRNAs.

  PloS one 20110101

• Complete genome sequence of Mycoplasma suis and insights into its biology and adaption to an erythrocyte niche.

  PloS one 20110101

• The E. coli anti-sigma factor Rsd: studies on the specificity and regulation of its expression.

  PloS one 20110101

• Evolution in an oncogenic bacterial species with extreme genome plasticity: Helicobacter pylori East Asian genomes.

  BMC microbiology 20110101

• Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion.

  BMC immunology 20110101

• Oligodendrocytes as regulators of neuronal networks during early postnatal development.

  PloS one 20110101

• The first sequenced carnivore genome shows complex host-endogenous retrovirus relationships.

  PloS one 20110101

• HIV-1 Vpu blocks recycling and biosynthetic transport of the intrinsic immunity factor CD317/tetherin to overcome the virion release restriction.

  mBio 20110101

• Genomic characterization of Haemophilus parasuis SH0165, a highly virulent strain of serovar 5 prevalent in China.

  PloS one 20110101

• Synaptically-competent neurons derived from canine embryonic stem cells by lineage selection with EGF and Noggin.

  PloS one 20110101

• Myelodysplastic syndrome and histone deacetylase inhibitors: 'to be or not to be acetylated'?

  Journal of biomedicine & biotechnology 20110101

• Litter gender composition and sex affect maternal behavior and DNA methylation levels of the oprm1 gene in rat offspring.

  Frontiers in psychiatry 20110101

• StralSV: assessment of sequence variability within similar 3D structures and application to polio RNA-dependent RNA polymerase.

  BMC bioinformatics 20110101

• A 5'-uridine amplifies miRNA/miRNA* asymmetry in Drosophila by promoting RNA-induced silencing complex formation.

  Silence 20110101

• Genetic and Immunological Factors Involved in Natural Resistance to HIV-1 Infection.

  The open virology journal 20110101

• Increasing the analytical sensitivity by oligonucleotides modified with para- and ortho-twisted intercalating nucleic acids--TINA.

  PloS one 20110101

• CD40 signaling synergizes with TLR-2 in the BCR independent activation of resting B cells.

  PloS one 20110101

• Biological responses to perfluorododecanoic acid exposure in rat kidneys as determined by integrated proteomic and metabonomic studies.

  PloS one 20110101

• Unexpected accumulation of ncm(5)U and ncm(5)S(2) (U) in a trm9 mutant suggests an additional step in the synthesis of mcm(5)U and mcm(5)S(2)U.

  PloS one 20110101

• Elevated expression of activation-induced cytidine deaminase in T and NK cells from patients with chronic active Epstein-Barr virus infection.

  European journal of dermatology : EJD 20110101

• Exposure to apoptotic activated CD4+ T cells induces maturation and APOBEC3G-mediated inhibition of HIV-1 infection in dendritic cells.

  PloS one 20110101

• Haloquadratum walsbyi: limited diversity in a global pond.

  PloS one 20110101

• Mechanical tuning of molecular machines for nucleotide recognition at the air-water interface.

  Nanoscale research letters 20110101

• A new drug design targeting the adenosinergic system for Huntington's disease.

  PloS one 20110101

• Use of specific chemical reagents for detection of modified nucleotides in RNA.

  Journal of nucleic acids 20110101

• [Oligo(2'-O-methylribonucleotides) with the insertions of 2'-bispyrenylmethylphosphorodiamidate nucleoside derivatives as perspective fluorescent probes for RNA detection].

  Bioorganicheskaia khimiia 20110101

• The role of unintegrated DNA in HIV infection.

  Retrovirology 20110101

• Transformation of human mesenchymal cells and skin fibroblasts into hematopoietic cells.

  PloS one 20110101

• Immunoglobulin G locus events in soft tissue sarcoma cell lines.

  PloS one 20110101

• Experimental Gonococcal Infection in Male Volunteers: Cumulative Experience with Neisseria gonorrhoeae Strains FA1090 and MS11mkC.

  Frontiers in microbiology 20110101

• Genome-wide local ancestry approach identifies genes and variants associated with chemotherapeutic susceptibility in African Americans.

  PloS one 20110101

• AID targeting in antibody diversity.

  Advances in immunology 20110101

• Signaling from the cytoplasm to the nucleus in striatal medium-sized spiny neurons.

  Frontiers in neuroanatomy 20110101

• HCV infection and B-cell lymphomagenesis.

  Advances in hematology 20110101

• A nucleoside anticancer drug, 1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)cytosine (TAS106), sensitizes cells to radiation by suppressing BRCA2 expression.

  Molecular cancer 20110101

• Strong association of 677 C>T substitution in the MTHFR gene with male infertility--a study on an indian population and a meta-analysis.

  PloS one 20110101

• Using animal models to disentangle the role of genetic, epigenetic, and environmental influences on behavioral outcomes associated with maternal anxiety and depression.

  Frontiers in psychiatry 20110101

• New hepatitis C therapies in clinical development.

  European journal of medical research 20110101

• Use of nucleic Acid analogs for the study of nucleic Acid interactions.

  Journal of nucleic acids 20110101

• Evidence for a two-metal-ion mechanism in the cytidyltransferase KdsB, an enzyme involved in lipopolysaccharide biosynthesis.

  PloS one 20110101

• Repression of human activation induced cytidine deaminase by miR-93 and miR-155.

  BMC cancer 20110101

• Epigenetic therapy for breast cancer.

  International journal of molecular sciences 20110101

• Antiviral activity and mechanism of action of novel thiourea containing chiral phosphonate on tobacco mosaic virus.

  International journal of molecular sciences 20110101

• Viral takeover of the host ubiquitin system.

  Frontiers in microbiology 20110101

• Mechanisms of resistance to decitabine in the myelodysplastic syndrome.

  PloS one 20110101

• Epigenetic regulation of caloric restriction in aging.

  BMC medicine 20110101

• Evaluation of fluorescent analogs of deoxycytidine for monitoring DNA transitions from duplex to functional structures.

  Journal of nucleic acids 20110101

• Innate inflammation and cancer: Is it time for cancer prevention?

  F1000 medicine reports 20110101

• Hepatitis C virus infection suppresses the interferon response in the liver of the human hepatocyte chimeric mouse.

  PloS one 20110101

• Cellular kinases incorporated into HIV-1 particles: passive or active passengers?

  Retrovirology 20110101

• Immunopathologic differences of Sjögren's syndrome versus sicca syndrome in HCV and HIV infection.

  Arthritis research & therapy 20110101

• Expression of APOBEC3G/3F and G-to-A hypermutation levels in HIV-1-infected children with different profiles of disease progression.

  PloS one 20110101

• The stability of a model substrate for topoisomerase 1-mediated DNA religation depends on the presence of mismatched base pairs.

  Journal of nucleic acids 20110101

• Inhibition of DNA methylation in somatic cells.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Use of capecitabine in management of early colon cancer.

  Cancer management and research 20110101

• Calculation of direct antiretroviral treatment costs and potential cost savings by using generics in the German HIV ClinSurv cohort.

  PloS one 20110101

• Replication protein A (RPA) hampers the processive action of APOBEC3G cytosine deaminase on single-stranded DNA.

  PloS one 20110101

• Genome of Mycoplasma haemofelis, unraveling its strategies for survival and persistence.

  Veterinary research 20110101

• Towards in vivo imaging of cancer sialylation.

  International journal of molecular imaging 20110101

• High resolution analysis of the chromatin landscape of the IgE switch region in human B cells.

  PloS one 20110101

• A functional interface at the rDNA connects rRNA synthesis, pre-rRNA processing and nucleolar surveillance in budding yeast.

  PloS one 20110101

• Mechanism and Function of the Outer Membrane Channel TolC in Multidrug Resistance and Physiology of Enterobacteria.

  Frontiers in microbiology 20110101

• Increased APOBEC3G and APOBEC3F expression is associated with low viral load and prolonged survival in simian immunodeficiency virus infected rhesus monkeys.

  Retrovirology 20110101

• Quantitative proteomic approaches to studying histone modifications.

  Current chemical genomics 20110101

• Naturally occurring genotype 2b/1a hepatitis C virus in the United States.

  Virology journal 20110101

• Nuclear reprogramming in mouse primordial germ cells: epigenetic contribution.

  Stem cells international 20110101

• Role of activation-induced cytidine deaminase in inflammation-associated cancer development.

  Advances in immunology 20110101

• TGF-β regulates DNA methyltransferase expression in prostate cancer, correlates with aggressive capabilities, and predicts disease recurrence.

  PloS one 20110101

• GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells.

  PloS one 20110101

• Activation-induced cytidine deaminase (AID)-associated multigene signature to assess impact of AID in etiology of diseases with inflammatory component.

  PloS one 20110101

• Recombinase-mediated cassette exchange as a novel method to study somatic hypermutation in Ramos cells.

  mBio 20110101

• Toll-like receptor agonists synergize with CD40L to induce either proliferation or plasma cell differentiation of mouse B cells.

  PloS one 20110101

• Specialized adaptation of a lactic acid bacterium to the milk environment: the comparative genomics of Streptococcus thermophilus LMD-9.

  Microbial cell factories 20110101

• Some aspects of purinergic signaling in the ventricular system of porcine brain.

  Acta veterinaria Scandinavica 20110101

• tRNA Modification and Genetic Code Variations in Animal Mitochondria.

  Journal of nucleic acids 20110101

• A common polymorphism in NR1H2 (LXRbeta) is associated with preeclampsia.

  BMC medical genetics 20110101

• Homologous expression of a subcomplex of Pyrococcus furiosus hydrogenase that interacts with pyruvate ferredoxin oxidoreductase.

  PloS one 20110101

• Weighted correlation network analysis (WGCNA) applied to the tomato fruit metabolome.

  PloS one 20110101

• Lymphotoxin-beta receptor blockade reduces CXCL13 in lacrimal glands and improves corneal integrity in the NOD model of Sjögren's syndrome.

  Arthritis research & therapy 20110101

• Developmental mechanisms in articular cartilage degradation in osteoarthritis.

  Arthritis 20110101

• Zebularine suppresses TGF-beta-induced lens epithelial cell-myofibroblast transdifferentiation by inhibiting MeCP2.

  Molecular vision 20110101

• An autoimmune disease prevented by anti-retroviral drugs.

  Retrovirology 20110101

• Molecular evolution of HIV-1 CRF01_AE Env in Thai patients.

  PloS one 20110101

• Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection.

  Retrovirology 20110101

• Epigenetics in breast cancer: what's new?

  Breast cancer research : BCR 20110101

• Novel strategy with gemcitabine for advanced pancreatic cancer.

  ISRN oncology 20110101

• Pharmacotherapeutic implications of the association between genomic instability at chromosome 15q13.3 and autism spectrum disorders.

  Clinical neuropharmacology 20110101

• An efficient vector system to modify cells genetically.

  PloS one 20110101

• A unique role of GATA1s in Down syndrome acute megakaryocytic leukemia biology and therapy.

  PloS one 20110101

• Bluetongue virus VP1 polymerase activity in vitro: template dependency, dinucleotide priming and cap dependency.

  PloS one 20110101

• miREE: miRNA recognition elements ensemble.

  BMC bioinformatics 20110101

• TRAF6 and IRF7 control HIV replication in macrophages.

  PloS one 20110101

• Epigenetic mechanisms of pulmonary hypertension.

  Pulmonary circulation 20110101

• Downregulation of APOBEC3G by xenotropic murine leukemia-virus related virus (XMRV) in prostate cancer cells.

  Virology journal 20110101

• Docking studies on novel analogues of 8 methoxy fluoroquinolones against GyrA mutants of Mycobacterium tuberculosis.

  BMC structural biology 20110101

• Tegafur/gimeracil/oteracil (S-1) approved for the treatment of advanced gastric cancer in adults when given in combination with cisplatin: a review comparing it with other fluoropyrimidine-based therapies.

  OncoTargets and therapy 20110101

• Modulation of phosducin-like protein 3 (PhLP3) levels promotes cytoskeletal remodelling in a MAPK and RhoA-dependent manner.

  PloS one 20110101

• Structural Basis for the Antiviral Activity of BST-2/Tetherin and Its Viral Antagonism.

  Frontiers in microbiology 20110101

• Structural Features of Antiviral APOBEC3 Proteins are Linked to Their Functional Activities.

  Frontiers in microbiology 20110101

• Biased use of the IGHV4 family and evidence for antigen selection in Chlamydophila psittaci-negative ocular adnexal extranodal marginal zone lymphomas.

  PloS one 20110101

• Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age.

  PloS one 20110101

• Circadian clocks in mouse and human CD4+ T cells.

  PloS one 20110101

• A concise review on epigenetic regulation: insight into molecular mechanisms.

  International journal of molecular sciences 20110101

• Mthfs is an Essential Gene in Mice and a Component of the Purinosome.

  Frontiers in genetics 20110101

• Replication of alphaviruses: a review on the entry process of alphaviruses into cells.

  Advances in virology 20110101

• Murine leukemia viruses: objects and organisms.

  Advances in virology 20110101

• XMRV Discovery and Prostate Cancer-Related Research.

  Advances in virology 20110101

• Intraperitoneal gemcitabine chemotherapy treatment for patients with resected pancreatic cancer: rationale and report of early data.

  International journal of surgical oncology 20110101

• Genome-wide essential gene identification in Streptococcus sanguinis.

  Scientific reports 20110101

• One-pot bio-synthesis: N-acetyl-D-neuraminic acid production by a powerful engineered whole-cell catalyst.

  Scientific reports 20110101

• Ribavirin restores ESR1 gene expression and tamoxifen sensitivity in ESR1 negative breast cancer cell lines.

  Clinical epigenetics 20110101

• Mannosylated liposomal cytidine 5' diphosphocholine prevent age related global moderate cerebral ischemia reperfusion induced mitochondrial cytochrome c release in aged rat brain.

  Neuroscience 20101229

• Local sequence targeting in the AID/APOBEC family differentially impacts retroviral restriction and antibody diversification.

  The Journal of biological chemistry 20101224

• APOBEC3 proteins expressed in mammary epithelial cells are packaged into retroviruses and can restrict transmission of milk-borne virions.

  Cell host & microbe 20101216

• Translocator protein (TSPO) ligand-Ara-C (cytarabine) conjugates as a strategy to deliver antineoplastic drugs and to enhance drug clinical potential.

  Molecular pharmaceutics 20101206

• A new site-directed transgenic rheumatoid factor mouse model demonstrates extrafollicular class switch and plasmablast formation.

  Autoimmunity 20101201

• Up-regulation of activation-induced cytidine deaminase causes genetic aberrations at the CDKN2b-CDKN2a in gastric cancer.

  Gastroenterology 20101201

• Lymphoid neogenesis in the giant papillae of patients with chronic allergic conjunctivitis.

  The Journal of allergy and clinical immunology 20101201

• Recapture of hepatic apolipoprotein B mRNA editing may be a promising strategy to relieve nephrotic dyslipidemia.

  Medical hypotheses 20101201

• Arsenic modulates APOBEC3G-mediated restriction to HIV-1 infection in myeloid dendritic cells.

  Journal of leukocyte biology 20101201

• A bioluminescent microbial biosensor for in vitro pretreatment assessment of cytarabine efficacy in leukemia.

  Clinical chemistry 20101201

• Assessment of mitochondria as a compartment for phosphatidylinositol synthesis in Solanum tuberosum.

  Plant physiology and biochemistry : PPB 20101201

• Nucleotide and nucleotide sugar analysis by liquid chromatography-electrospray ionization-mass spectrometry on surface-conditioned porous graphitic carbon.

  Analytical chemistry 20101201

• Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice.

  The Journal of clinical investigation 20101201

• Two special topics on the avian influenza virus and on epigenetics, have drawn much attention.

  Science China. Life sciences 20101201

• Cytotoxicity and antileukaemic activity of new duplexes linking 3-C-ethynylcytidine and 5-fluorodeoxyuridine.

  Anticancer research 20101201

• A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress.

  PLoS genetics 20101201

• Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly.

  PLoS pathogens 20101201

• Identification of mouse mutant cells exhibiting plastic mutant phenotype II; ionizing radiation-induced mutant phenotype plasticity is not dependent on DNA methylation of the hypoxanthine phosphoribosyl transferase gene in mouse FM3A cells.

  Bioscience trends 20101201

• Cytosine methyltransferases as tumor markers.

  Current genomics 20101201

• Profound differences in virus population genetics correspond to protection from CD4 decline resulting from feline lentivirus coinfection.

  Viruses 20101201

• Intrinsic defects in B cell response to seasonal influenza vaccination in elderly humans.

  Vaccine 20101129

• When bacteria become mutagenic and carcinogenic: lessons from H. pylori.

  Mutation research 20101128

• Estrogen receptors bind to and activate the HOXC4/HoxC4 promoter to potentiate HoxC4-mediated activation-induced cytosine deaminase induction, immunoglobulin class switch DNA recombination, and somatic hypermutation.

  The Journal of biological chemistry 20101126

• 2'-Deoxy-2'-spirocyclopropylcytidine revisited: a new and selective inhibitor of the hepatitis C virus NS5B polymerase.

  Journal of medicinal chemistry 20101125

• Chemoselective multicomponent one-pot assembly of purine precursors in water.

  Journal of the American Chemical Society 20101124

• A recombinant α-(2→3)-sialyltransferase with an extremely broad acceptor substrate specificity from Photobacterium sp. JT-ISH-224 can transfer N-acetylneuraminic acid to inositols.

  Carbohydrate research 20101122

• Measuring topology of low-intensity DNA methylation sites for high-throughput assessment of epigenetic drug-induced effects in cancer cells.

  Experimental cell research 20101115

• Label-free DNA methylation analysis using opto-fluidic ring resonators.

  Biosensors & bioelectronics 20101115

• Differential anti-APOBEC3G activity of HIV-1 Vif proteins derived from different subtypes.

  The Journal of biological chemistry 20101112

• How the CCA-adding enzyme selects adenine over cytosine at position 76 of tRNA.

  Science (New York, N.Y.) 20101112

• Isolation and identification of ester impurities in RG7128, an HCV polymerase inhibitor.

  Journal of pharmaceutical and biomedical analysis 20101102

• Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes.

  Biochimica et biophysica acta 20101101

• Production of cytidine 5'-diphosphorylcholine with high utilization of ATP by whole cells of Saccharomyces cerevisiae.

  Bioresource technology 20101101

• Role of tyrosine 33 residue for the stabilization of the tetrameric structure of human cytidine deaminase.

  International journal of biological macromolecules 20101101

• Activation of the type I interferon pathway in primary Sjogren's syndrome.

  Journal of autoimmunity 20101101

• DNA methylation regulates cocaine-induced behavioral sensitization in mice.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20101101

• E2A-positive gastric MALT lymphoma has weaker plasmacytoid infiltrates and stronger expression of the memory B-cell-associated miR-223: possible correlation with stage and treatment response.

  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20101101

• Analysis of hydrophilic and lipophilic choline compounds in radioresistant and radiosensitive glioblastoma cell lines by HILIC-ESI-MS/MS.

  Analytical and bioanalytical chemistry 20101101

• Association of RNase L with a Ras GTPase-activating-like protein IQGAP1 in mediating the apoptosis of a human cancer cell-line.

  The FEBS journal 20101101

• Innate immunity in resistance to HIV infection.

  The Journal of infectious diseases 20101101

• A cyclooxygenase-2/prostaglandin E2 pathway augments activation-induced cytosine deaminase expression within replicating human B cells.

  Journal of immunology (Baltimore, Md. : 1950) 20101101

• Msh6 protects mature B cells from lymphoma by preserving genomic stability.

  The American journal of pathology 20101101

• Contribution of thymidylate synthase to gemcitabine therapy for advanced pancreatic cancer.

  Pancreas 20101101

• Nanomechanical recognition measurements of individual DNA molecules reveal epigenetic methylation patterns.

  Nature nanotechnology 20101101

• Alkaloidal constituents of Tinospora crispa.

  Natural product communications 20101101

• Targeted serum metabolite profiling of nucleosides in esophageal adenocarcinoma.

  Rapid communications in mass spectrometry : RCM 20101030

• An integrated genomic and epigenomic approach predicts therapeutic response to zebularine in human liver cancer.

  Science translational medicine 20101020

• Method for the rapid detection and molecular characterization of DNA alkylating agents by MALDI-TOF mass spectrometry.

  Analytical chemistry 20101015

• Photoelectron spectroscopic study of the hydrated nucleoside anions: Uridine(-)(H(2)O)(n=0-2), cytidine(-)(H(2)O)(n=0-2), and thymidine(-)(H(2)O)(n=0,1).

  The Journal of chemical physics 20101014

• Archaeal RibL: a new FAD synthetase that is air sensitive.

  Biochemistry 20101012

• Molecular insight into the conformational dynamics of the Elongin BC complex and its interaction with HIV-1 Vif.

  Journal of molecular biology 20101008

• PCR-based methods for CDA K27Q and A70T genotyping: genotypes and alleles distribution in a central Italy population.

  Molecular biology reports 20101001

• Biophysical characterization of recombinant proteins: a key to higher structural genomics success.

  Journal of structural biology 20101001

• An investigation of intracellular glycosylation activities in CHO cells: effects of nucleotide sugar precursor feeding.

  Biotechnology and bioengineering 20101001

• Influence of cytidine deaminase on antitumor activity of 2'-deoxycytidine analogs in vitro and in vivo.

  Drug metabolism and disposition: the biological fate of chemicals 20101001

• Editing site analysis in a gymnosperm mitochondrial genome reveals similarities with angiosperm mitochondrial genomes.

  Current genetics 20101001

• Regulation of HIV-1 infection in cells derived from purified CD34+ cells through manipulation of APOBEC3G expression.

  Current HIV research 20101001

• Human APOBEC3G-mediated editing can promote HIV-1 sequence diversification and accelerate adaptation to selective pressure.

  Journal of virology 20101001

• Extracellular nucleotides elicit cytosolic free calcium oscillations in Arabidopsis.

  Plant physiology 20101001

• Metabolomic profiling reveals biochemical pathways and biomarkers associated with pathogenesis in cystic fibrosis cells.

  The Journal of biological chemistry 20101001

• Enhanced growth inhibition by combined DNA methylation/HDAC inhibitors in lung tumor cells with silenced CDKN2A.

  International journal of oncology 20101001

• Activation-induced cytidine deaminase accelerates clonal evolution in BCR-ABL1-driven B-cell lineage acute lymphoblastic leukemia.

  Cancer research 20101001

• BAK1 gene variation and abdominal aortic aneurysms--results may have been prematurely overrated.

  Human mutation 20101001

• Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5.

  Cell 20101001

• Cytidine deaminases: AIDing DNA demethylation?

  Genes & development 20101001

• Gene expression levels as predictive markers of outcome in pancreatic cancer after gemcitabine-based adjuvant chemotherapy.

  Neoplasia (New York, N.Y.) 20101001

• The effect of epigenetic regulation of fucosylation on TRAIL-induced apoptosis.

  Glycoconjugate journal 20101001

• Host genetics and HIV-1: the final phase?

  PLoS pathogens 20101001

• Hyper-IgM syndrome--a case report and a clinical perspective.

  European annals of allergy and clinical immunology 20101001

• Inhibitors of the Hepatitis C Virus RNA-Dependent RNA Polymerase NS5B.

  Viruses 20101001

• Cyclic cytidine 3',5'-monophosphate (cCMP) signals via cGMP kinase I.

  FEBS letters 20100924

• Partially active HIV-1 Vif alleles facilitate viral escape from specific antiretrovirals.

  AIDS (London, England) 20100924

• AID-induced genotoxic stress promotes B cell differentiation in the germinal center via ATM and LKB1 signaling.

  Molecular cell 20100924

• Development and application of an HILIC-MS/MS method for the quantitation of nucleotides in infant formula.

  Journal of agricultural and food chemistry 20100922

• Identification of two APOBEC3F splice variants displaying HIV-1 antiviral activity and contrasting sensitivity to Vif.

  The Journal of biological chemistry 20100917

• Evolution of ectopic lymphoid neogenesis and in situ autoantibody production in autoimmune nonobese diabetic mice: cellular and molecular characterization of tertiary lymphoid structures in pancreatic islets.

  Journal of immunology (Baltimore, Md. : 1950) 20100915

• apoB and apobec1, two genes key to lipid metabolism, are transcriptionally regulated by p53.

  Cell cycle (Georgetown, Tex.) 20100915

• The role of p53 in nutrients levels.

  Cell cycle (Georgetown, Tex.) 20100915

• Metal-organic polyhedra for selective sensing of ribonucleosides through the cooperation of hydrogen-bonding interactions.

  Dalton transactions (Cambridge, England : 2003) 20100907

• Innate immune signaling induces high levels of TC-specific deaminase activity in primary monocyte-derived cells through expression of APOBEC3A isoforms.

  The Journal of biological chemistry 20100903

• Synthesis, spectroscopic and DNA alkylating properties of malondialdehyde (MDA) bis-imine fluorescent adducts.

  Molecular bioSystems 20100901

• To automate or not to automate: this is the question.

  Journal of structural and functional genomics 20100901

• Letter to the editor: pharmacokinetics of gemcitabine in non-small-cell lung cancer patients: impact of the 79A>C cytidine deaminase polymorphism.

  European journal of clinical pharmacology 20100901

• A critical function of toll-like receptor-3 in the induction of anti-human immunodeficiency virus activities in macrophages.

  Immunology 20100901

• Widespread genomic breaks generated by activation-induced cytidine deaminase are prevented by homologous recombination.

  Nature immunology 20100901

• No evidence of an association between the APOBEC3B deletion polymorphism and susceptibility to HIV infection and AIDS in Japanese and Indian populations.

  The Journal of infectious diseases 20100901

• The spontaneous rearrangement of 2,4-dinitrophenyl substituent in ribonucleosides under neutral conditions.

  Nucleosides, nucleotides & nucleic acids 20100901

• Sulfoalkylbetaine-based monolithic column with mixed-mode of hydrophilic interaction and strong anion-exchange stationary phase for capillary electrochromatography.

  Electrophoresis 20100901

• Modulation of embryo-forming capacity in culture through the expression of Brassica genes involved in the regulation of the shoot apical meristem.

  Journal of experimental botany 20100901

• 14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination.

  Nature structural & molecular biology 20100901

• Frail hypotheses in evolutionary biology.

  PLoS genetics 20100901

• New treatments for chronic hepatitis C.

  The Korean journal of hepatology 20100901

• Determination of nucleotides, nucleosides and their transformation products in Cordyceps by ion-pairing reversed-phase liquid chromatography-mass spectrometry.

  Journal of chromatography. A 20100820

• PTIP promotes chromatin changes critical for immunoglobulin class switch recombination.

  Science (New York, N.Y.) 20100820

• Synthesis of nucleotidylated poliovirus VPg proteins.

  The Journal of organic chemistry 20100820

• Immunology. Double TIP-ping.

  Science (New York, N.Y.) 20100820

• Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues .

  Biochemistry 20100810

• Ion-pair high-performance liquid chromatography with diode array detection coupled to dual electrospray atmospheric pressure chemical ionization time-of-flight mass spectrometry for the determination of nucleotides in baby foods.

  Journal of chromatography. A 20100806

• Host Dependent Evolutionary Patterns and the Origin of 2009 H1N1 Pandemic Influenza.

  PLoS currents 20100804

• APOBEC3G directly binds Hepatitis B virus core protein in cell and cell free systems.

  Virus research 20100801

• Correlations of creatine and six related pyrimidine metabolites and diabetic nephropathy in Chinese type 2 diabetic patients.

  Clinical biochemistry 20100801

• 13C-direct detected NMR experiments for the sequential J-based resonance assignment of RNA oligonucleotides.

  Journal of biomolecular NMR 20100801

• Multi-site-specific 16S rRNA methyltransferase RsmF from Thermus thermophilus.

  RNA (New York, N.Y.) 20100801

• Cutting edge: CTNNBL1 is dispensable for Ig class switch recombination.

  Journal of immunology (Baltimore, Md. : 1950) 20100801

• Population pharmacokinetics of gemcitabine and its metabolite in Japanese cancer patients: impact of genetic polymorphisms.

  Clinical pharmacokinetics 20100801

• The metabolic enzyme CTP synthase forms cytoskeletal filaments.

  Nature cell biology 20100801

• Helicobacter pylori-induced activation-induced cytidine deaminase expression and carcinogenesis.

  Current opinion in immunology 20100801

• Calcitriol enhances gemcitabine anti-tumor activity in vitro and in vivo by promoting apoptosis in a human pancreatic carcinoma model system.

  Cell cycle (Georgetown, Tex.) 20100801

• Nucleotides in canine colostrum and milk at different stages of lactation.

  Archives of animal nutrition 20100801

• GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin variable region DNA.

  The Journal of biological chemistry 20100730

• Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein.

  Journal of molecular biology 20100723

• Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo.

  Journal of immunology (Baltimore, Md. : 1950) 20100715

• Formation of stable BOBO-3 H-aggregate complexes hinders DNA hybridization.

  The journal of physical chemistry. B 20100715

• The in vivo toxicity of hydroxyurea depends on its direct target catalase.

  The Journal of biological chemistry 20100709

• Cytidylyl and uridylyl cyclase activity of bacillus anthracis edema factor and Bordetella pertussis CyaA.

  Biochemistry 20100706

• Enzymatic synthesis of unique sialyloligosaccharides using marine bacterial alpha-(2-->3)- and alpha-(2-->6)-sialyltransferases.

  Carbohydrate research 20100702

• Controlling somatic hypermutation in immunoglobulin variable and switch regions.

  Immunologic research 20100701

• Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction.

  Nucleic acids research 20100701

• Epigenetic regulation of photoperiodic flowering.

  Plant signaling & behavior 20100701

• APOBEC3G contributes to HIV-1 variation through sublethal mutagenesis.

  Journal of virology 20100701

• TP53 mutations coincide with the ectopic expression of activation-induced cytidine deaminase in the fibroblast-like synoviocytes derived from a fraction of patients with rheumatoid arthritis.

  Clinical and experimental immunology 20100701

• Identification and characterization of important residues in the catalytic mechanism of CMP-Neu5Ac synthetase from Neisseria meningitidis.

  The FEBS journal 20100701

• Clinical and molecular characterization of X-linked hyper-IgM syndrome patients in China.

  Scandinavian journal of immunology 20100701

• Adaptive evolution of Mus Apobec3 includes retroviral insertion and positive selection at two clusters of residues flanking the substrate groove.

  PLoS pathogens 20100701

• The BRCT domain of PARP-1 is required for immunoglobulin gene conversion.

  PLoS biology 20100701

• Quasispecies theory and the behavior of RNA viruses.

  PLoS pathogens 20100701

• New trends in nucleoside biotechnology.

  Acta naturae 20100701

• Complete genome sequence of Archaeoglobus profundus type strain (AV18).

  Standards in genomic sciences 20100630

• Apobec-1 complementation factor modulates liver regeneration by post-transcriptional regulation of interleukin-6 mRNA stability.

  The Journal of biological chemistry 20100618

• An RNA-directed nucleoside anti-metabolite, 1-(3-C-ethynyl-beta-d-ribo-pentofuranosyl)cytosine (ECyd), elicits antitumor effect via TP53-induced Glycolysis and Apoptosis Regulator (TIGAR) downregulation.

  Biochemical pharmacology 20100615

• Incorporation of gemcitabine and cytarabine into DNA by DNA polymerase beta and ligase III/XRCC1.

  Biochemistry 20100615

• High expression of AID and active class switch recombination might account for a more aggressive disease in unmutated CLL patients: link with an activated microenvironment in CLL disease.

  Blood 20100603

• Expression of gemcitabine- and cisplatin-related genes in non-small-cell lung cancer.

  The pharmacogenomics journal 20100601

• Subepithelial dendritic B cells in orofacial granulomatosis.

  Inflammatory bowel diseases 20100601

• The cellular context of AID expressing cells in fish lymphoid tissues.

  Developmental and comparative immunology 20100601

• Enhanced expression of lymphomagenesis-related genes in peripheral blood B cells of chronic hepatitis C patients.

  Clinical immunology (Orlando, Fla.) 20100601

• Pharmacokinetics of gemcitabine in non-small-cell lung cancer patients: impact of the 79A>C cytidine deaminase polymorphism.

  European journal of clinical pharmacology 20100601

• Efficacy of 2'-C-methylcytidine against yellow fever virus in cell culture and in a hamster model.

  Antiviral research 20100601

• Electrochemical simulation of oxidation processes involving nucleic acids monitored with electrospray ionization-mass spectrometry.

  Analytical and bioanalytical chemistry 20100601

• Simultaneous determination of nine nucleosides and nucleobases in different Fritillaria species by HPLC-diode array detector.

  Journal of separation science 20100601

• p53 represses class switch recombination to IgG2a through its antioxidant function.

  Journal of immunology (Baltimore, Md. : 1950) 20100601

• Nucleotides and nucleosides in ovine and caprine milk during lactation.

  Journal of dairy science 20100601

• The epigenetic landscape of latent Kaposi sarcoma-associated herpesvirus genomes.

  PLoS pathogens 20100601

• The SOCS-box of HIV-1 Vif interacts with ElonginBC by induced-folding to recruit its Cul5-containing ubiquitin ligase complex.

  PLoS pathogens 20100601

• Study of apoptosis induction and deoxycytidine kinase/cytidine deaminase modulation in the synergistic interaction of a novel ceramide analog and gemcitabine in pancreatic cancer cells.

  Nucleosides, nucleotides & nucleic acids 20100601

• Constraint-based model of Shewanella oneidensis MR-1 metabolism: a tool for data analysis and hypothesis generation.

  PLoS computational biology 20100601

• [Progress in the study of HIV-1 Vif and related inhibitors].

  Yao xue xue bao = Acta pharmaceutica Sinica 20100601

• Small molecular compounds inhibit HIV-1 replication through specifically stabilizing APOBEC3G.

  The Journal of biological chemistry 20100528

• Enhancement of hypermutation frequency in the chicken B cell line DT40 for efficient diversification of the antibody repertoire.

  Biochemical and biophysical research communications 20100528

• Structural model for deoxycytidine deamination mechanisms of the HIV-1 inactivation enzyme APOBEC3G.

  The Journal of biological chemistry 20100521

• Diverse morphologies of self-assemblies from homoditopic 1,18-nucleotide-appended bolaamphiphiles: effects of nucleobases and complementary oligonucleotides.

  Small (Weinheim an der Bergstrasse, Germany) 20100521

• Targeting activation-induced cytidine deaminase overcomes tumor evasion of immunotherapy by CTLs.

  Journal of immunology (Baltimore, Md. : 1950) 20100515

• Impact of cytidine deaminase polymorphisms on toxicity after gemcitabine: the question is still ongoing.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100510

• Determinants of sequence-specificity within human AID and APOBEC3G.

  DNA repair 20100504

• N(3)-o-toluyl-fluorouracil inhibits human hepatocellular carcinoma cell growth via sustained release of 5-FU.

  Cancer chemotherapy and pharmacology 20100501

• Can CDA deficiency explain tumour lysis syndrome in a child with neuroblastoma receiving gemcitabine?

  Pediatric blood & cancer 20100501

• Enhancement of intestinal absorption of 2-methyl cytidine prodrugs.

  Drug delivery 20100501

• Higher expression levels of activation-induced cytidine deaminase distinguish hairy cell leukemia from hairy cell leukemia-variant and splenic marginal zone lymphoma.

  Leukemia 20100501

• The recruitment of activation induced cytidine deaminase to the immunoglobulin locus by a regulatory element.

  Molecular immunology 20100501

• Hypermutation induced by APOBEC-1 overexpression can be eliminated.

  RNA (New York, N.Y.) 20100501

• AID-induced T-lymphoma or B-leukemia/lymphoma in a mouse BMT model.

  Leukemia 20100501

• AID in reprogramming: quick and efficient: identification of a key enzyme called AID, and its activity in DNA demethylation, may help to overcome a pivotal epigenetic barrier in reprogramming somatic cells toward pluripotency.

  BioEssays : news and reviews in molecular, cellular and developmental biology 20100501

• S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth.

  Molecular cancer therapeutics 20100501

• Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis.

  PLoS pathogens 20100501

• A survey of genomic traces reveals a common sequencing error, RNA editing, and DNA editing.

  PLoS genetics 20100501

• Inhibition of LINE-1 and Alu retrotransposition by exosomes encapsidating APOBEC3G and APOBEC3F.

  Virology 20100425

• Interaction of Vpx and apolipoprotein B mRNA-editing catalytic polypeptide 3 family member A (APOBEC3A) correlates with efficient lentivirus infection of monocytes.

  The Journal of biological chemistry 20100416

• Cloning and expression of activation induced cytidine deaminase from Bos taurus.

  Veterinary immunology and immunopathology 20100415

• Activation-induced cytidine deaminase splicing patterns in chronic lymphocytic leukemia.

  Blood cells, molecules & diseases 20100415

• (-)-Carbodine: enantiomeric synthesis and in vitro antiviral activity against various strains of influenza virus including H5N1 (avian influenza) and novel 2009 H1N1 (swine flu).

  Bioorganic & medicinal chemistry letters 20100415

• CyDNA: synthesis and replication of highly Cy-dye substituted DNA by an evolved polymerase.

  Journal of the American Chemical Society 20100414

• Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.

  Cell 20100402

• Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells.

  Breast cancer research and treatment 20100401

• Chemical stability of 4'-azidocytidine and its prodrug balapiravir.

  Drug development and industrial pharmacy 20100401

• Cytoskeletal proteins bound to heat-shock protein 70 may elicit resistance to simian immunodeficiency virus infection of CD4(+) T cells.

  Immunology 20100401

• The role of macrophages in the development and progression of AIDS-related non-Hodgkin lymphoma.

  Journal of leukocyte biology 20100401

• In vitro assessment of cytochrome P450 inhibition and induction potential of azacitidine.

  Cancer chemotherapy and pharmacology 20100401

• Molecular characterization of Pleurodeles waltl activation-induced cytidine deaminase.

  Molecular immunology 20100401

• Agmatine-conjugated cytidine in a tRNA anticodon is essential for AUA decoding in archaea.

  Nature chemical biology 20100401

• Update on the hyper immunoglobulin M syndromes.

  British journal of haematology 20100401

• Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity.

  International immunology 20100401

• Transcription factors PU.1 and IRF4 regulate activation induced cytidine deaminase in chicken B cells.

  Molecular immunology 20100401

• The genetic code: an archaeal path to literacy.

  Nature chemical biology 20100401

• Gastrointestinal and hepatic manifestations of primary immune deficiency diseases.

  Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20100401

• Structural basis for Fe-S cluster assembly and tRNA thiolation mediated by IscS protein-protein interactions.

  PLoS biology 20100401

• The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin.

  PLoS pathogens 20100401

• A microarray-based genetic screen for yeast chronological aging factors.

  PLoS genetics 20100401

• Epigenetic regulation of a murine retrotransposon by a dual histone modification mark.

  PLoS genetics 20100401

• The expression of survivin and its related genes in adipocyte-derived stem cell by demethylation.

  Korean journal of anesthesiology 20100401

• [Studies on photoinduced electron and proton transfer reactions of nucleic acid and aromatic ketone].

  Guang pu xue yu guang pu fen xi = Guang pu 20100401

• Antiviral therapy for hepatitis C virus: beyond the standard of care.

  Viruses 20100401

• Synthesis of nucleoside 5'-O-alpha,beta-methylene-beta-triphosphates and evaluation of their potency towards inhibition of HIV-1 reverse transcriptase.

  Organic & biomolecular chemistry 20100321

• Microarray analysis of tonsils in immunoglobulin A nephropathy patients.

  Biochemical and biophysical research communications 20100319

• Susceptibility of xenotropic murine leukemia virus-related virus (XMRV) to retroviral restriction factors.

  Proceedings of the National Academy of Sciences of the United States of America 20100316

• Deficiency in APOBEC2 leads to a shift in muscle fiber type, diminished body mass, and myopathy.

  The Journal of biological chemistry 20100305

• Expression of nucleoside transporters, deoxycitidine kinase, ribonucleotide reductase regulatory subunits, and gemcitabine catabolic enzymes in primary ovarian cancer.

  Cancer chemotherapy and pharmacology 20100301

• Evaluation of the role of three candidate human kinases in the conversion of the hepatitis C virus inhibitor 2'-C-methyl-cytidine to its 5'-monophosphate metabolite.

  Antiviral research 20100301

• Structural and functional analyses of Mycobacterium tuberculosis Rv3315c-encoded metal-dependent homotetrameric cytidine deaminase.

  Journal of structural biology 20100301

• Viro-immunological dynamics in HIV-1-infected subjects receiving once-a-week emtricitabine to delay treatment change after failure: a pilot randomised trial.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20100301

• Activation-induced cytidine deaminase splice variants are defective because of the lack of structural support for the catalytic site.

  Journal of immunology (Baltimore, Md. : 1950) 20100301

• Stability of 5-fluoro-2'-deoxycytidine and tetrahydrouridine in combination.

  AAPS PharmSciTech 20100301

• Multiple receptor tyrosine kinases are expressed in adult rat retinal ganglion cells as revealed by single-cell degenerate primer polymerase chain reaction.

  Upsala journal of medical sciences 20100301

• AID for reprogramming.

  Cell research 20100301

• Activation-induced cytidine deaminase expression in diffuse large B-cell lymphoma with a paracortical growth pattern: a lymphoma of possible interfollicular large B-cell origin.

  Archives of pathology & laboratory medicine 20100301

• No association between AICDA 7888 C/T polymorphism, Helicobacter pylori seropositivity, and the risk of atrophic gastritis and gastric cancer in Japanese.

  Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20100301

• Synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate and kinetic studies of Mycobacterium tuberculosis IspF.

  Chemistry & biology 20100226

• CCR6 ligands inhibit HIV by inducing APOBEC3G.

  Blood 20100225

• Reprogramming towards pluripotency requires AID-dependent DNA demethylation.

  Nature 20100225

• Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.

  Nature 20100225

• Inactivation of Lactobacillus leichmannii ribonucleotide reductase by 2',2'-difluoro-2'-deoxycytidine 5'-triphosphate: adenosylcobalamin destruction and formation of a nucleotide-based radical.

  Biochemistry 20100223

• Malignant transformation of Slp65-deficient pre-B cells involves disruption of the Arf-Mdm2-p53 tumor suppressor pathway.

  Blood 20100218

• c-Myc overexpression promotes a germinal center-like program in Burkitt's lymphoma.

  Oncogene 20100211

• Use of Drosophila deoxynucleoside kinase to study mechanism of toxicity and mutagenicity of deoxycytidine analogs in Escherichia coli.

  DNA repair 20100204

• RNA-seq: from technology to biology.

  Cellular and molecular life sciences : CMLS 20100201

• Trans-sialidase activity of Photobacterium damsela alpha2,6-sialyltransferase and its application in the synthesis of sialosides.

  Glycobiology 20100201

• The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction.

  American journal of physiology. Regulatory, integrative and comparative physiology 20100201

• AID protein expression in chronic lymphocytic leukemia/small lymphocytic lymphoma is associated with poor prognosis and complex genetic alterations.

  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20100201

• The PPR protein encoded by the LOVASTATIN INSENSITIVE 1 gene is involved in RNA editing at three sites in mitochondria of Arabidopsis thaliana.

  The Plant journal : for cell and molecular biology 20100201

• Deficiency in activation-induced cytidine deaminase promotes systemic autoimmunity in lpr mice on a C57BL/6 background.

  Clinical and experimental immunology 20100201

• DNA-dependent protein kinase (DNA-PK)-deficient human glioblastoma cells are preferentially sensitized by Zebularine.

  Carcinogenesis 20100201

• Status of APOBEC3G/F in cells and progeny virions modulated by Vif determines HIV-1 infectivity.

  Microbes and infection 20100201

• Identification of two common variants contributing to serum apolipoprotein B levels in Mexicans.

  Arteriosclerosis, thrombosis, and vascular biology 20100201

• B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers.

  Nature immunology 20100201

• High-resolution melting analysis of sequence variations in the cytidine deaminase gene (CDA) in patients with cancer treated with gemcitabine.

  Therapeutic drug monitoring 20100201

• APOBEC3 proteins mediate the clearance of foreign DNA from human cells.

  Nature structural & molecular biology 20100201

• Inostamycin prevents malignant phenotype of cancer: inhibition of phosphatidylinositol synthesis provides a therapeutic advantage for head and neck squamous cell carcinoma.

  Cell biology international 20100201

• Walking the AID tightrope.

  Nature immunology 20100201

• Involvement of the histaminergic system in cytidine 5'-diphosphocholine-induced reversal of critical haemorrhagic hypotension in rats.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100201

• Different interaction between HIV-1 Vif and its cellular target proteins APOBEC3G/APOBEC3F.

  The journal of medical investigation : JMI 20100201

• Viral resistance in hepatitis B: prevalence and management.

  Current gastroenterology reports 20100201

• Oiling the brain: a review of randomized controlled trials of omega-3 fatty acids in psychopathology across the lifespan.

  Nutrients 20100201

• Application of the dipeptidyl peptidase IV (DPPIV/CD26) based prodrug approach to different amine-containing drugs.

  Journal of medicinal chemistry 20100128

• An unusual pattern of CytR and CRP binding energetics at Escherichia coli cddP suggests a unique blend of class I and class II mediated activation.

  Biochemistry 20100126

• Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: implications for therapeutics.

  Expert reviews in molecular medicine 20100122

• pH induced DNA folding at interface.

  The journal of physical chemistry. B 20100121

• Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID.

  The Journal of experimental medicine 20100118

• APOBEC3G expression is dysregulated in primary HIV-1 infection and polymorphic variants influence CD4+ T-cell counts and plasma viral load.

  AIDS (London, England) 20100116

• Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces.

  Structure (London, England : 1993) 20100113

• Different isoforms of the B-cell mutator activation-induced cytidine deaminase are aberrantly expressed in BCR-ABL1-positive acute lymphoblastic leukemia patients.

  Leukemia 20100101

• Phosphatidylglycerol depletion affects photosystem II activity in Synechococcus sp. PCC 7942 cells.

  Photosynthesis research 20100101

• Identification of immediate response genes dominantly expressed in juvenile resistant and susceptible Biomphalaria glabrata snails upon exposure to Schistosoma mansoni.

  Molecular and biochemical parasitology 20100101

• Generation of a recombinant single-chain variable fragment (scFv) targeting 5-methyl-2'-deoxycytidine.

  Journal of biochemistry 20100101

• The inhibitory effect of apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G) and its family members on the activity of cellular microRNAs.

  Progress in molecular and subcellular biology 20100101

• Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway.

  RNA (New York, N.Y.) 20100101

• The expression of apoB mRNA editing factors is not the sole determinant for the induction of editing in differentiating Caco-2 cells.

  Biochemical and biophysical research communications 20100101

• Cytidine deaminase residual activity in serum is a predictive marker of early severe toxicities in adults after gemcitabine-based chemotherapies.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100101

• Decitabine in the treatment of myelodysplastic syndromes.

  Expert review of anticancer therapy 20100101

• Comment on 'Gut-associated lymphoid tissue contains the molecular machinery to support T-cell-dependent and T-cell-independent class switch recombination'.

  Mucosal immunology 20100101

• Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming.

  Nature medicine 20100101

• Idarubicin plus behenoyl cytarabine and 6-thioguanine compares favorably with idarubicin plus cytarabine-based regimen for children with previously untreated acute myeloid leukemia: 10-year retrospective, multicenter study in Korea.

  Journal of Korean medical science 20100101

• Deletions of immunoglobulin heavy chain and T cell receptor gene regions are uniquely associated with lymphoid blast transformation of chronic myeloid leukemia.

  BMC genomics 20100101

• Differentiation of intestinal epithelial cells mediated by cell confluence and/or exogenous nucleoside supplementation.

  Cells, tissues, organs 20100101

• The site specific demethylation in the 5'-regulatory area of NMDA receptor 2B subunit gene associated with CIE-induced up-regulation of transcription.

  PloS one 20100101

• Antidepressant stimulation of CDP-diacylglycerol synthesis does not require monoamine reuptake inhibition.

  BMC neuroscience 20100101

• Two forms of activation-induced cytidine deaminase differing in their ability to bind agarose.

  PloS one 20100101

• A comparison of azacitidine and decitabine activities in acute myeloid leukemia cell lines.

  PloS one 20100101

• Alternative splicing and extensive RNA editing of human TPH2 transcripts.

  PloS one 20100101

• [Expression and subcellular localization of APOBEC3G in peripheral blood mononuclear cells and liver tissues of chronic HBV patients].

  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20100101

• Replication, pathogenesis and transmission of pandemic (H1N1) 2009 virus in non-immune pigs.

  PloS one 20100101

• Expression and functional activity of nucleoside transporters in human choroid plexus.

  Cerebrospinal fluid research 20100101

• Genetic polymorphisms of matrix metalloproteinases and their inhibitors in potentially malignant and malignant lesions of the head and neck.

  Journal of biomedical science 20100101

• Mechanisms of chromosomal rearrangement in the human genome.

  BMC genomics 20100101

• HIV-induced immune activation: pathogenesis and clinical relevance - summary of a workshop organized by the German AIDS Society (DAIG e.v.) and the ICH Hamburg, Hamburg, Germany, November 22, 2008.

  European journal of medical research 20100101

• Glucocorticoid receptor gene polymorphisms do not affect growth in fetal and early postnatal life. The Generation R Study.

  BMC medical genetics 20100101

• Quality evaluation of mycelial Antrodia camphorata using high-performance liquid chromatography (HPLC) coupled with diode array detector and mass spectrometry (DAD-MS).

  Chinese medicine 20100101

• A nuclear factor-binding domain in the 5'-untranslated region of the amyloid precursor protein promoter: implications for the regulation of gene expression.

  BMC research notes 20100101

• Masitinib combined with standard gemcitabine chemotherapy: in vitro and in vivo studies in human pancreatic tumour cell lines and ectopic mouse model.

  PloS one 20100101

• [Expression of Gemcitabine-resistance-related gene and polymorphism of ribonucleotide reductase M1 gene promoter in Gemcitabine-resistant A549/Gem and NCI-H460/Gem cell lines].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20100101

• Diverse functions for DNA and RNA editing in the immune system.

  RNA biology 20100101

• How to slice: snapshots of Argonaute in action.

  Silence 20100101

• Genome-wide DNA demethylation in mammals.

  Genome biology 20100101

• Circadian rhythm and its role in malignancy.

  Journal of circadian rhythms 20100101

• Host hindrance to HIV-1 replication in monocytes and macrophages.

  Retrovirology 20100101

• CXCR4 mediated chemotaxis is regulated by 5T4 oncofetal glycoprotein in mouse embryonic cells.

  PloS one 20100101

• The transition from noncoded to coded protein synthesis: did coding mRNAs arise from stability-enhancing binding partners to tRNA?

  Biology direct 20100101

• The macrophage in HIV-1 infection: from activation to deactivation?

  Retrovirology 20100101

• Variability in a dominant block to SIV early reverse transcription in rhesus monkey cells predicts in vivo viral replication and time to death.

  Virology journal 20100101

• Modulation of the virus-receptor interaction by mutations in the V5 loop of feline immunodeficiency virus (FIV) following in vivo escape from neutralising antibody.

  Retrovirology 20100101

• Clinical significance of phosphatidyl inositol synthase overexpression in oral cancer.

  BMC cancer 20100101

• Genome-wide in silico screen for CCCH-type zinc finger proteins of Trypanosoma brucei, Trypanosoma cruzi and Leishmania major.

  BMC genomics 20100101

• Biochemical characterization of enzyme fidelity of influenza A virus RNA polymerase complex.

  PloS one 20100101

• Non-long terminal repeat (non-LTR) retrotransposons: mechanisms, recent developments, and unanswered questions.

  Mobile DNA 20100101

• Metabolic effects of influenza virus infection in cultured animal cells: Intra- and extracellular metabolite profiling.

  BMC systems biology 20100101

• Mitochondrial genomes of acrodont lizards: timing of gene rearrangements and phylogenetic and biogeographic implications.

  BMC evolutionary biology 20100101

• Biosynthesis and molecular genetics of polyketides in marine dinoflagellates.

  Marine drugs 20100101

• Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors.

  PloS one 20100101

• AID and somatic hypermutation.

  Advances in immunology 20100101

• Copy number variation and cytidine analogue cytotoxicity: a genome-wide association approach.

  BMC genomics 20100101

• Active site plasticity revealed from the structure of the enterobacterial N-ribohydrolase RihA bound to a competitive inhibitor.

  BMC structural biology 20100101

• Hepatitis B virus and Homo sapiens proteome-wide analysis: A profusion of viral peptide overlaps in neuron-specific human proteins.

  Biologics : targets & therapy 20100101

• Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies.

  Journal of translational medicine 20100101

• Positive selection of HIV host factors and the evolution of lentivirus genes.

  BMC evolutionary biology 20100101

• The evolution of transcription-associated biases of mutations across vertebrates.

  BMC evolutionary biology 20100101

• MSH2/MSH6 complex promotes error-free repair of AID-induced dU:G mispairs as well as error-prone hypermutation of A:T sites.

  PloS one 20100101

• Innate immune recognition and activation during HIV infection.

  Retrovirology 20100101

• High-affinity consensus binding of target RNAs by the STAR/GSG proteins GLD-1, STAR-2 and Quaking.

  BMC molecular biology 20100101

• Cell type mediated resistance of vesicular stomatitis virus and Sendai virus to ribavirin.

  PloS one 20100101

• Effects of sizes and conformations of fish-scale collagen peptides on facial skin qualities and transdermal penetration efficiency.

  Journal of biomedicine & biotechnology 20100101

• Uncovering the complexity of transcriptomes with RNA-Seq.

  Journal of biomedicine & biotechnology 20100101

• CD40 ligand (CD154) incorporated into HIV virions induces activation-induced cytidine deaminase (AID) expression in human B lymphocytes.

  PloS one 20100101

• RNA vaccines in cancer treatment.

  Journal of biomedicine & biotechnology 20100101

• Extensive analysis of D7S486 in primary gastric cancer supports TESTIN as a candidate tumor suppressor gene.

  Molecular cancer 20100101

• A liquid chromatographic method for routine analysis of 5'-mononucleotides in pediatric formulas.

  Journal of AOAC International 20100101

• Rationalisation of the differences between APOBEC3G structures from crystallography and NMR studies by molecular dynamics simulations.

  PloS one 20100101

• Paralysis and delayed Z-disc formation in the Xenopus tropicalis unc45b mutant dicky ticker.

  BMC developmental biology 20100101

• PAR-CliP--a method to identify transcriptome-wide the binding sites of RNA binding proteins.

  Journal of visualized experiments : JoVE 20100101

• Comparison of koala LPCoLN and human strains of Chlamydia pneumoniae highlights extended genetic diversity in the species.

  BMC genomics 20100101

• The interaction between AID and CIB1 is nonessential for antibody gene diversification by gene conversion or class switch recombination.

  PloS one 20100101

• Histone H2A and H2B are monoubiquitinated at AID-targeted loci.

  PloS one 20100101

• Large-scale analysis of structural, sequence and thermodynamic characteristics of A-to-I RNA editing sites in human Alu repeats.

  BMC genomics 20100101

• Genotypic and phenotypic properties of Candida parapsilosis sensu strictu strains isolated from different geographic regions and body sites.

  BMC microbiology 20100101

• Apobec 3G efficiently reduces infectivity of the human exogenous gammaretrovirus XMRV.

  PloS one 20100101

• Oxidative stress and DNA methylation in prostate cancer.

  Obstetrics and gynecology international 20100101

• The battle between virus and host: modulation of Toll-like receptor signaling pathways by virus infection.

  Mediators of inflammation 20100101

• Role of DNA methylation in miR-200c/141 cluster silencing in invasive breast cancer cells.

  BMC research notes 20100101

• Inherited defects of immunoglobulin class switch recombination.

  Advances in experimental medicine and biology 20100101

• Induction and assessment of class switch recombination in purified murine B cells.

  Journal of visualized experiments : JoVE 20100101

• Unique DNA repair gene variations and potential associations with the primary antibody deficiency syndromes IgAD and CVID.

  PloS one 20100101

• Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.

  PloS one 20100101

• Cytidine-Ag+-purine base complexes as studied by electrospray ionization mass spectrometry.

  European journal of mass spectrometry (Chichester, England) 20100101

• Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeutics.

  Genome medicine 20100101

• Induction of erythroid differentiation in human erythroleukemia cells by depletion of malic enzyme 2.

  PloS one 20100101

• Mutagenesis dependent upon the combination of activation-induced deaminase expression and a double-strand break.

  Molecular immunology 20100101

• APOBEC-1-mediated RNA editing.

  Wiley interdisciplinary reviews. Systems biology and medicine 20100101

• Epigenetic approaches in the treatment of myelodysplastic syndromes: clinical utility of azacitidine.

  OncoTargets and therapy 20100101

• Glycinergic transmission: physiological, developmental and pathological implications.

  Frontiers in molecular neuroscience 20100101

• Coordination Reactions and Noncovalent Interactions of Polyamines with Nucleotides in Binary Systems and with Nucleotides and Copper(II) Ion in Ternary Systems.

  Bioinorganic chemistry and applications 20100101

• Effect of genetic alterations of cytarabine- metabolizing enzymes in childhood acute lymphoblastic leukemia.

  Hematology/oncology and stem cell therapy 20100101

• Equitoxic doses of 5-azacytidine and 5-aza-2'deoxycytidine induce diverse immediate and overlapping heritable changes in the transcriptome.

  PloS one 20100101

• S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis).

  Journal of translational medicine 20100101

• Biomarkers for colorectal cancer.

  International journal of molecular sciences 20100101

• Interferon-alpha induces high expression of APOBEC3G and STAT-1 in vitro and in vivo.

  International journal of molecular sciences 20100101

• Safety and efficacy of azacitidine in myelodysplastic syndromes.

  Drug design, development and therapy 20100101

• Interferon-alpha mediates restriction of human immunodeficiency virus type-1 replication in primary human macrophages at an early stage of replication.

  PloS one 20100101

• The effect of differentiating and apoptotic agents on notch signalling pathway in hepatoblastoma.

  Hepato-gastroenterology 20100101

• Chemotherapy resistance in metastatic breast cancer: the evolving role of ixabepilone.

  Breast cancer research : BCR 20100101

• T-cell epitope prediction and immune complex simulation using molecular dynamics: state of the art and persisting challenges.

  Immunome research 20100101

• Biological rationale for the use of DNA methyltransferase inhibitors as new strategy for modulation of tumor response to chemotherapy and radiation.

  Molecular cancer 20100101

• The mouse 'xenotropic' gammaretroviruses and their XPR1 receptor.

  Retrovirology 20100101

• From Duke to King's: Michael Malim wins the 2010 Retrovirology Prize.

  Retrovirology 20100101

• Gemcitabine functions epigenetically by inhibiting repair mediated DNA demethylation.

  PloS one 20100101

• Marine bacterial sialyltransferases.

  Marine drugs 20100101

• RNA editing of nuclear transcripts in Arabidopsis thaliana.

  BMC genomics 20100101

• Discovery and characterization of medaka miRNA genes by next generation sequencing platform.

  BMC genomics 20100101

• The N-terminus of GalE induces tmRNA activity in Escherichia coli.

  PloS one 20100101

• Intestinal Host-Microbe Interactions under Physiological and Pathological Conditions.

  International journal of inflammation 20100101

• Role of HIV-1 nucleocapsid protein in HIV-1 reverse transcription.

  RNA biology 20100101

• The xenotropic murine leukemia virus-related retrovirus debate continues at first international workshop.

  Retrovirology 20100101

• Horizontal acquisition of multiple mitochondrial genes from a parasitic plant followed by gene conversion with host mitochondrial genes.

  BMC biology 20100101

• Gene transfer: anything goes in plant mitochondria.

  BMC biology 20100101

• Selective induction of DNA repair pathways in human B cells activated by CD4+ T cells.

  PloS one 20100101

• Epigenomics in cancer management.

  Cancer management and research 20100101

• Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates.

  PloS one 20100101

• Analysis of microRNA expression in the prepubertal testis.

  PloS one 20100101

• Simultaneous spectrophotometric estimation of tenofovir disoproxil fumarate and Lamivudine in three component tablet formulation containing efavirenz.

  Indian journal of pharmaceutical sciences 20100101

• Towards a systems approach in the genetic analysis of archaea: Accelerating mutant construction and phenotypic analysis in Haloferax volcanii.

  Archaea (Vancouver, B.C.) 20100101

• The mechanisms regulating the subcellular localization of AID.

  Nucleus (Austin, Tex.) 20100101

• Efficacy of a Lactococcus lactis ΔpyrG vaccine delivery platform expressing chromosomally integrated hly from Listeria monocytogenes.

  Bioengineered bugs 20100101

• Polymorphisms in promoter sequences of MDM2, p53, and p16 genes in normal Japanese individuals.

  Genetics and molecular biology 20100101

• Initiation of HIV Reverse Transcription.

  Viruses 20100101

• Calprotectin (S100A8/S100A9) and myeloperoxidase: co-regulators of formation of reactive oxygen species.

  Toxins 20100101

• Treatment of acute, non-traumatic pain using a combination of diclofenac-cholestyramine, uridine triphosphate, cytidine monophosphate, and hydroxycobalamin.

  Proceedings of the Western Pharmacology Society 20100101

• Towards Inhibition of Vif-APOBEC3G Interaction: Which Protein to Target?

  Advances in virology 20100101

• The efficacy of citroline in the treatment of ischemic stroke and primary hypertensive intracereral hemorrhage; a review article.

  ARYA atherosclerosis 20100101

• Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options.

  Blood 20091224

• Ultrashort fluorescence lifetimes of hydrogen-bonded base pairs of guanosine and cytidine in solution.

  The journal of physical chemistry. B 20091224

• Modulating unimolecular charge transfer by exciting bridge vibrations.

  Journal of the American Chemical Society 20091223

• Functional characterization of intracellular Dictyostelium discoideum P2X receptors.

  The Journal of biological chemistry 20091211

• Suppression of APP-containing vesicle trafficking and production of beta-amyloid by AID/DHHC-12 protein.

  Journal of neurochemistry 20091201

• Multiple ways of targeting APOBEC3-virion infectivity factor interactions for anti-HIV-1 drug development.

  Trends in pharmacological sciences 20091201

• An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization.

  Blood 20091201

• Multiple layers of B cell memory with different effector functions.

  Nature immunology 20091201

• Free energy calculation of modified base-pair formation in explicit solvent: A predictive model.

  RNA (New York, N.Y.) 20091201

• Modulation of activation-induced cytidine deaminase by curcumin in Helicobacter pylori-infected gastric epithelial cells.

  Helicobacter 20091201

• Antiviral activity of the interferon-induced cellular protein BST-2/tetherin.

  AIDS research and human retroviruses 20091201

• RNA editing in plant mitochondria: 20 years later.

  IUBMB life 20091201

• [A novel mechanism for H. pylori-induced cell damage--induction of gene mutation by AID].

  Nihon rinsho. Japanese journal of clinical medicine 20091201

• Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance.

  Neoplasia (New York, N.Y.) 20091201

• Thermostability of chimeric cytidine deaminase variants produced by DNA shuffling.

  Journal of microbiology and biotechnology 20091201

• Cytosinium-hydrogen maleate-cytosine (1/1/1).

  Acta crystallographica. Section E, Structure reports online 20091201

• Effect of type-I interferon on retroviruses.

  Viruses 20091201

• Mutation rates and intrinsic fidelity of retroviral reverse transcriptases.

  Viruses 20091201

• Crystal structure of a mammalian CTP: phosphocholine cytidylyltransferase catalytic domain reveals novel active site residues within a highly conserved nucleotidyltransferase fold.

  The Journal of biological chemistry 20091127

• Synthesis, crystallization, and biological evaluation of an orally active prodrug of gemcitabine.

  Journal of medicinal chemistry 20091126

• AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations.

  Molecular cell 20091125

• A hydrodynamic analysis of APOBEC3G reveals a monomer-dimer-tetramer self-association that has implications for anti-HIV function.

  Biochemistry 20091117

• Clinical and laboratory findings in hyper-IgM syndrome with novel CD40L and AICDA mutations.

  Journal of clinical immunology 20091101

• Profiling the repertoire of phenotypes influenced by environmental cues that occur during asexual reproduction.

  Genome research 20091101

• Mapping the ribonucleolytic active site of bovine seminal ribonuclease. The binding of pyrimidinyl phosphonucleotide inhibitors.

  European journal of medicinal chemistry 20091101

• The AKV murine leukemia virus is restricted and hypermutated by mouse APOBEC3.

  Journal of virology 20091101

• Gut-associated lymphoid tissue contains the molecular machinery to support T-cell-dependent and T-cell-independent class switch recombination.

  Mucosal immunology 20091101

• RESOPS: a database for analyzing the correspondence of RNA editing sites to protein three-dimensional structures.

  Plant & cell physiology 20091101

• A coming-of-age story: activation-induced cytidine deaminase turns 10.

  Nature immunology 20091101

• Titrimetric immunohistochemical evaluation of DNA hypomethylation in uterine tumours.

  Journal of clinical pathology 20091101

• A study of new Arabidopsis chloroplast RNA editing mutants reveals general features of editing factors and their target sites.

  The Plant cell 20091101

• Synthesis and anti-hepatitis C virus activity of 2'(beta)-hydroxyethyl and 4'(alpha)-hydroxymethyl carbodine analogues.

  Nucleosides, nucleotides & nucleic acids 20091101

• Synthesis of 2'-N-formamido nucleosides and biological evaluation.

  Nucleosides, nucleotides & nucleic acids 20091101

• Molecular characterization of hybridoma subclones spontaneously switching at high frequencies in vitro.

  Journal of immunological methods 20091031

• Speckled-like pattern in the germinal center (SLIP-GC), a nuclear GTPase expressed in activation-induced deaminase-expressing lymphomas and germinal center B cells.

  The Journal of biological chemistry 20091030

• Ubiquitin-fusion as a strategy to modulate protein half-life: A3G antiviral activity revisited.

  Virology 20091025

• Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase.

  Nature 20091022

• Anti-hepatitis C virus activity of novel beta-d-2'-C-methyl-4'-azido pyrimidine nucleoside phosphoramidate prodrugs.

  Antiviral chemistry & chemotherapy 20091019

• Determination of nucleosides and nucleobases in different species of Cordyceps by capillary electrophoresis-mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20091015

• A potentially versatile nucleotide hydrolysis activity of group II chaperonin monomers from Thermoplasma acidophilum.

  Biochemistry 20091013

• Biochemical basis of immunological and retroviral responses to DNA-targeted cytosine deamination by activation-induced cytidine deaminase and APOBEC3G.

  The Journal of biological chemistry 20091009

• SNP analyses in cytarabine metabolizing enzymes in AML patients and their impact on treatment response and patient survival: identification of CDA SNP C-451T as an independent prognostic parameter for survival.

  Leukemia 20091001

• Effect of NH4+ and glycerol on cytidine 5'-diphosphocholine synthesis in Saccharomyces cerevisiae.

  Bioresource technology 20091001

• The current structural and functional understanding of APOBEC deaminases.

  Cellular and molecular life sciences : CMLS 20091001

• APOBEC3B deletion and risk of HIV-1 acquisition.

  The Journal of infectious diseases 20091001

• NF-kappaB family of transcription factor facilitates gene conversion in chicken B cells.

  Molecular immunology 20091001

• Somatic hypermutation: processivity of the cytosine deaminase AID and error-free repair of the resulting uracils.

  Cell cycle (Georgetown, Tex.) 20091001

• Synthesis and in vitro activities of new anticancer duplex drugs linking 2'-deoxy-5-fluorouridine (5-FdU) with 3'-C-ethynylcytidine (ECyd) via a phosphodiester bonding.

  Bioorganic & medicinal chemistry 20091001

• Temporal regulation of Ig gene diversification revealed by single-cell imaging.

  Journal of immunology (Baltimore, Md. : 1950) 20091001

• A novel mechanism for inflammation-associated carcinogenesis; an important role of activation-induced cytidine deaminase (AID) in mutation induction.

  Journal of molecular medicine (Berlin, Germany) 20091001

• DNA mismatch repair (MMR)-dependent 5-fluorouracil cytotoxicity and the potential for new therapeutic targets.

  British journal of pharmacology 20091001

• Membrane-bound Fas ligand only is essential for Fas-induced apoptosis.

  Nature 20091001

• Genetic factors influencing cytarabine therapy.

  Pharmacogenomics 20091001

• APOBEC3 proteins inhibit LINE-1 retrotransposition in the absence of ORF1p binding.

  Annals of the New York Academy of Sciences 20091001

• [Inhibitory effect of a HBV vector plasmid expressing A3C on HBV replication].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20091001

• APOBEC deaminases-mutases with defensive roles for immunity.

  Science in China. Series C, Life sciences 20091001

• DNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site.

  Biochemical pharmacology 20090915

• Mice deficient for CD137 ligand are predisposed to develop germinal center-derived B-cell lymphoma.

  Blood 20090910

• Phosphoramidate prodrugs of 2'-C-methylcytidine for therapy of hepatitis C virus infection.

  Journal of medicinal chemistry 20090910

• Imatinib resistance and progression of CML to blast crisis: somatic hypermutation AIDing the way.

  Cancer cell 20090908

• The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia.

  Cancer cell 20090908

• Rice OGR1 encodes a pentatricopeptide repeat-DYW protein and is essential for RNA editing in mitochondria.

  The Plant journal : for cell and molecular biology 20090901

• Cyclic phosphoramidates as prodrugs of 2'-C-methylcytidine.

  European journal of medicinal chemistry 20090901

• AtECB2, a pentatricopeptide repeat protein, is required for chloroplast transcript accD RNA editing and early chloroplast biogenesis in Arabidopsis thaliana.

  The Plant journal : for cell and molecular biology 20090901

• DNA deaminases: AIDing hormones in immunity and cancer.

  Journal of molecular medicine (Berlin, Germany) 20090901

• Defining APOBEC3 expression patterns in human tissues and hematopoietic cell subsets.

  Journal of virology 20090901

• Activation-induced cytidine deaminase expression and activity in the absence of germinal centers: insights into hyper-IgM syndrome.

  Journal of immunology (Baltimore, Md. : 1950) 20090901

• Forward and reverse genetics to identify genes involved in the age-related resistance response in Arabidopsis thaliana.

  Molecular plant pathology 20090901

• Increased expression of activation-induced cytidine deaminase is associated with anti-CCP and rheumatoid factor in rheumatoid arthritis.

  Scandinavian journal of immunology 20090901

• Accurate measurement of DNA methylation that is traceable to the international system of units.

  Analytical chemistry 20090901

• [Mutational analysis of Meq, RLORF4, RLORF12 and 132bpr genes of epidemic Marek's disease virus strains highly passaged on chicken embryo fibroblast].

  Bing du xue bao = Chinese journal of virology 20090901

• Synthesis and anti-HCV evaluation of 4'(alpha)-ethyl and 2'(beta)-methyl-carbodine analogues.

  Nucleosides, nucleotides & nucleic acids 20090901

• Interleukin-27 inhibition of HIV-1 involves an intermediate induction of type I interferon.

  Blood 20090827

• Origin of pyrimidine deoxyribonucleotide pools in perfused rat heart: implications for 3'-azido-3'-deoxythymidine-dependent cardiotoxicity.

  The Biochemical journal 20090827

• Fishing in the (deoxyribonucleotide) pool.

  The Biochemical journal 20090827

• Anion exchange liquid chromatography for the determination of nucleotides in baby and/or functional foods.

  Journal of agricultural and food chemistry 20090826

• Molecular structure and biochemical properties of the HCCH-Zn2+ site in HIV-1 Vif.

  Biochemistry 20090825

• A portable hot spot recognition loop transfers sequence preferences from APOBEC family members to activation-induced cytidine deaminase.

  The Journal of biological chemistry 20090821

• Synthesis and conformational analysis of locked carbocyclic analogues of 1,3-diazepinone riboside, a high-affinity cytidine deaminase inhibitor.

  The Journal of organic chemistry 20090821

• Methylation of zebularine: a quantum mechanical study incorporating interactive 3D pdf graphs.

  The journal of physical chemistry. B 20090820

• A novel method to assess the full genome methylation profile using monoclonal antibody combined with the high throughput based microarray approach.

  Epigenetics 20090816

• IgM in microbial infections: taken for granted?

  Immunology letters 20090815

• Ambivalent incorporation of the fluorescent cytosine analogues tC and tCo by human DNA polymerase alpha and Klenow fragment.

  Biochemistry 20090811

• NMR and computational studies of stereoisomeric equine estrogen-derived DNA cytidine adducts in oligonucleotide duplexes: opposite orientations of diastereomeric forms.

  Biochemistry 20090804

• Reliable synthesis of various nucleoside diphosphate glycopyranoses.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090803

• S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination.

  The Journal of experimental medicine 20090803

• IFN-alpha amplifies human naive B cell TLR-9-mediated activation and Ig production.

  Journal of leukocyte biology 20090801

• Abstracts of the 2008 ISSOL Meeting. August 24-29, 2008. Florence, Italy.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20090801

• The application of phosphoramidate ProTide technology to the potent anti-HCV compound 4'-azidocytidine (R1479).

  Bioorganic & medicinal chemistry letters 20090801

• Ribonucleotide reductase as one important target of [Tris(1,10-phenanthroline)lanthanum(III)] trithiocyanate (KP772).

  Current cancer drug targets 20090801

• A fast capillary electrophoresis method for separation and quantification of modified nucleosides in urinary samples.

  Analytical chemistry 20090801

• Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell-stimulating programs in basophils.

  Nature immunology 20090801

• Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli.

  Nature chemical biology 20090801

• Cholangiocarcinomas associated with long-term inflammation express the activation-induced cytidine deaminase and germinal center-associated nuclear protein involved in immunoglobulin V-region diversification.

  International journal of oncology 20090801

• Effects of aging on B cell function.

  Current opinion in immunology 20090801

• Cytosolic 5'-nucleotidase III (NT5C3): gene sequence variation and functional genomics.

  Pharmacogenetics and genomics 20090801

• Preparation and evaluation of a sulfoalkylbetaine-based zwitterionic monolithic column for CEC of polar analytes.

  Electrophoresis 20090801

• Computational study on the conformation and vibration frequencies of β-sheet of ε-polylysine in vacuum.

  International journal of molecular sciences 20090801

• Potential of DNMT and its Epigenetic Regulation for Lung Cancer Therapy.

  Current genomics 20090801

• Synthesis and in vitro activity evaluation of 2',3'-C-dimethyl carbocyclic nucleoside analogues as potential anti-HCV agents.

  Nucleosides, nucleotides & nucleic acids 20090801

• PK-PD modeling of 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine and the enhanced antitumor effect of its phospholipid derivatives in long-circulating liposomes.

  International journal of pharmaceutics 20090730

• AID constrains germinal center size by rendering B cells susceptible to apoptosis.

  Blood 20090716

• Development of a sensitive and selective LC-MS/MS method for simultaneous determination of gemcitabine and 2,2-difluoro-2-deoxyuridine in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090715

• Progesterone inhibits activation-induced deaminase by binding to the promoter.

  Journal of immunology (Baltimore, Md. : 1950) 20090715

• Interaction of cytidine 5'-monophosphate with Au(111): an in situ infrared spectroscopic study.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20090713

• Immunology: B cells break the rules.

  Nature 20090709

• Mechanisms promoting translocations in editing and switching peripheral B cells.

  Nature 20090709

• Quantum mechanics/molecular mechanics investigation of the mechanism of phosphate transfer in human uridine-cytidine kinase 2.

  Organic & biomolecular chemistry 20090707

• Coordinate regulation of glycan degradation and polysaccharide capsule biosynthesis by a prominent human gut symbiont.

  The Journal of biological chemistry 20090703

• Zebularine suppresses the apoptotic potential of 5-fluorouracil via cAMP/PKA/CREB pathway against human oral squamous cell carcinoma cells.

  Cancer chemotherapy and pharmacology 20090701

• GATA1 mutations in patients with down syndrome and acute megakaryoblastic leukaemia do not always confer a good prognosis.

  Pediatric blood & cancer 20090701

• Development of gene therapy in association with clinically used cytotoxic deoxynucleoside analogues.

  Cancer gene therapy 20090701

• Duodenal and nodal follicular lymphomas are distinct: the former lacks activation-induced cytidine deaminase and follicular dendritic cells despite ongoing somatic hypermutations.

  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20090701

• Antisense transcripts of V(D)J rearrangements; artifacts caused by false priming?

  Molecular immunology 20090701

• Influence of nucleotide identity on ribose 2'-hydroxyl reactivity in RNA.

  RNA (New York, N.Y.) 20090701

• AID upmutants isolated using a high-throughput screen highlight the immunity/cancer balance limiting DNA deaminase activity.

  Nature structural & molecular biology 20090701

• The effect of allogeneic in vitro stimulation and in vivo immunization on memory CD4(+) T-cell APOBEC3G expression and HIV-1 infectivity.

  European journal of immunology 20090701

• CEM-T4 cells do not lack an APOBEC3G cofactor.

  PLoS pathogens 20090701

• Possible contribution of DNase gamma to immunoglobulin V gene diversification.

  Immunology letters 20090630

• An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model.

  Journal of molecular biology 20090626

• Decreased expression of cholesterol 7alpha-hydroxylase and altered bile acid metabolism in Apobec-1-/- mice lead to increased gallstone susceptibility.

  The Journal of biological chemistry 20090619

• Total syntheses of a conformationally locked North-type methanocarba puromycin analogue and a dinucleotide derivative.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090615

• Synthesis of terminally modified oligonucleotides and their hybridization dependence on the size of the target RNAs.

  Organic & biomolecular chemistry 20090607

• Viral hepatitis-associated intrahepatic cholangiocarcinoma shares common disease processes with hepatocellular carcinoma.

  British journal of cancer 20090602

• Accurate micro- and macro- gas phase basicities of hydroxyl-radical-modified pyrimidines estimated by advanced quantum chemistry methods.

  Journal of molecular modeling 20090601

• Decreased glutamate/glutamine levels may mediate cytidine's efficacy in treating bipolar depression: a longitudinal proton magnetic resonance spectroscopy study.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090601

• The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells.

  Leukemia 20090601

• Molecular cloning and expression of a novel cholinephosphotransferase involved in glycoglycerophospholipid biosynthesis of Mycoplasma fermentans.

  Current microbiology 20090601

• Analysis of urinary nucleosides as helper tumor markers in hepatocellular carcinoma diagnosis.

  Rapid communications in mass spectrometry : RCM 20090601

• G-to-A hypermutation in hepatitis B virus (HBV) and clinical course of patients with chronic HBV infection.

  The Journal of infectious diseases 20090601

• Regulation of activation-induced cytidine deaminase DNA deamination activity in B-cells by Ser38 phosphorylation.

  Biochemical Society transactions 20090601

• Bilateral renal-cell carcinoma associated with an acquired VHL mutation and long-term trichloroethylene exposure.

  Clinical nephrology 20090601

• Zinc coordination is required for and regulates transcription activation by Epstein-Barr nuclear antigen 1.

  PLoS pathogens 20090601

• Global HIV-1 molecular epidemiology with special reference to genetic analysis of HIV-1 subtypes circulating in North India: functional and pathogenic implications of genetic variation.

  Indian journal of experimental biology 20090601

• [Accessory proteins of HIV and innate anti-retroviral factors].

  Uirusu 20090601

• APOBEC3G cytidine deaminase association with coronavirus nucleocapsid protein.

  Virology 20090525

• Gram-positive bacteria enhance HIV-1 susceptibility in Langerhans cells, but not in dendritic cells, via Toll-like receptor activation.

  Blood 20090521

• Apparent non-statistical binding in a ditopic receptor for guanosine.

  Organic & biomolecular chemistry 20090521

• Inhibition of HIV-1 infection and replication by enhancing viral incorporation of innate anti-HIV-1 protein A3G: a non-pathogenic Nef mutant-based anti-HIV strategy.

  The Journal of biological chemistry 20090515

• 2'-deoxy-1-methylpseudocytidine, a stable analog of 2'-deoxy-5-methylisocytidine.

  Bioorganic & medicinal chemistry 20090515

• Ionization energies of aqueous nucleic acids: photoelectron spectroscopy of pyrimidine nucleosides and ab initio calculations.

  Journal of the American Chemical Society 20090513

• Restriction of HIV-1 by APOBEC3G is cytidine deaminase-dependent.

  Virology 20090510

• Primary central nervous system lymphoma: tumor-related clones exist in the blood and bone marrow with evidence for separate development.

  Blood 20090507

• Enzymatic synthesis of sialylation substrates powered by a novel polyphosphate kinase (PPK3).

  Organic & biomolecular chemistry 20090507

• Early severe toxicities after capecitabine intake: possible implication of a cytidine deaminase extensive metabolizer profile.

  Cancer chemotherapy and pharmacology 20090501

• Lasting epigenetic influence of early-life adversity on the BDNF gene.

  Biological psychiatry 20090501

• Identification and functional characterization of a novel cytidine deaminase in a gastropod abalone, Haliotis diversicolor supertexta.

  Developmental and comparative immunology 20090501

• DNA demethylation protects from cleavable complex stabilization and DNA strand breakage induced by the topoisomerase type I inhibitor camptothecin.

  Mutagenesis 20090501

• Alternative induction of meiotic recombination from single-base lesions of DNA deaminases.

  Genetics 20090501

• A common CD4 gene variant is associated with an increased risk of HIV-1 infection in Kenyan female commercial sex workers.

  The Journal of infectious diseases 20090501

• Ultra-deep pyrosequencing of hepatitis B virus quasispecies from nucleoside and nucleotide reverse-transcriptase inhibitor (NRTI)-treated patients and NRTI-naive patients.

  The Journal of infectious diseases 20090501

• Phase II studies of gemcitabine and cisplatin in heavily and minimally pretreated metastatic breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090501

• 1-(3-C-Ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), a novel potent inhibitor of RNA polymerase, potentiates the cytotoxicity of CDDP in human cancer cells both in vitro and in vivo.

  International journal of oncology 20090501

• HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation.

  Nature immunology 20090501

• Thymidine kinase and uridine-cytidine kinase from Entamoeba histolytica: cloning, characterization, and search for specific inhibitors.

  Parasitology 20090501

• HIV and SIV infection: the role of cellular restriction and immune responses in viral replication and pathogenesis.

  APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20090501

• A cytidine deaminase edits C to U in transfer RNAs in Archaea.

  Science (New York, N.Y.) 20090501

• Active nuclear import and cytoplasmic retention of activation-induced deaminase.

  Nature structural & molecular biology 20090501

• Mechanisms of APOBEC3G-catalyzed processive deamination of deoxycytidine on single-stranded DNA.

  Nature structural & molecular biology 20090501

• HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC.

  PLoS pathogens 20090501

• Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2.

  PLoS pathogens 20090501

• Deaminase-independent inhibition of parvoviruses by the APOBEC3A cytidine deaminase.

  PLoS pathogens 20090501

• Vpu antagonizes BST-2-mediated restriction of HIV-1 release via beta-TrCP and endo-lysosomal trafficking.

  PLoS pathogens 20090501

• [Recent advances in DNA demethylation in tumor therapy].

  Zhonghua bing li xue za zhi = Chinese journal of pathology 20090501

• Contrasting behavior of conformationally locked carbocyclic nucleosides of adenosine and cytidine as substrates for deaminases.

  Nucleosides, nucleotides & nucleic acids 20090501

• Synthesis of ansa1-cytidines.

  Nucleosides, nucleotides & nucleic acids 20090501

• A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy.

  Journal of medicinal chemistry 20090423

• DFT study of the interaction of cytidine and 2'-deoxycytidine with Li+, Na+, and K+: effects of metal cationization on sugar puckering and stability of the N-glycosidic bond.

  Carbohydrate research 20090421

• Methodological approaches in application of synthetic lethality screening towards anticancer therapy.

  British journal of cancer 20090421

• The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence.

  Proceedings of the National Academy of Sciences of the United States of America 20090421

• Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting.

  Blood 20090416

• A novel method for the detection of point mutation in DNA using single-base-coded CdS nanoprobes.

  Biosensors & bioelectronics 20090415

• A robust quantitative solid phase immunoassay for the acute phase protein C-reactive protein (CRP) based on cytidine 5'-diphosphocholine coupled dendrimers.

  Journal of immunological methods 20090415

• Role of RNase L in apoptosis induced by 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine.

  Cancer chemotherapy and pharmacology 20090401

• Analysis of urinary nucleosides as potential tumor markers in human colorectal cancer by high performance liquid chromatography/electrospray ionization tandem mass spectrometry.

  Clinica chimica acta; international journal of clinical chemistry 20090401

• Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 production.

  Molecular immunology 20090401

• Exogenous adenosine reduces the mitochondrial membrane potential of murine oocytes during the latter half of in vitro maturation and pronuclear formation following chemical activation.

  The Journal of reproduction and development 20090401

• Specific recruitment of protein kinase A to the immunoglobulin locus regulates class-switch recombination.

  Nature immunology 20090401

• AID and RPA: PKA makes the connection local.

  Nature immunology 20090401

• Balancing AID and DNA repair during somatic hypermutation.

  Trends in immunology 20090401

• Likely role of APOBEC3G-mediated G-to-A mutations in HIV-1 evolution and drug resistance.

  PLoS pathogens 20090401

• Impaired antibody response causes persistence of prototypic T cell-contained virus.

  PLoS biology 20090401

• Are viruses inhibited by APOBEC3 molecules from their host species?

  PLoS pathogens 20090401

• Synthesis and activity of modified cytidine 5'-monophosphate probes for T4 RNA ligase 1.

  Nucleosides, nucleotides & nucleic acids 20090401

• Characterization and kinetics of phosphopantothenoylcysteine synthetase from Enterococcus faecalis.

  Biochemistry 20090331

• Homozygous CDA*3 is a major cause of life-threatening toxicities in gemcitabine-treated Japanese cancer patients.

  British journal of cancer 20090324

• Enhanced replication and pathogenesis of Moloney murine leukemia virus in mice defective in the murine APOBEC3 gene.

  Virology 20090315

• Ectopic germinal centers are rare in Sjogren's syndrome salivary glands and do not exclude autoreactive B cells.

  Journal of immunology (Baltimore, Md. : 1950) 20090315

• Dissecting APOBEC3G substrate specificity by nucleoside analog interference.

  The Journal of biological chemistry 20090313

• Somatic hypermutation of immunoglobulin genes: lessons from proliferating cell nuclear antigenK164R mutant mice.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312

• Preface.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312

• Immunoglobulin class switch recombination: study through human natural mutants.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312

• Activation-induced cytidine deaminase-mediated hypermutation in the DT40 cell line.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312

• Non-homologous end joining in class switch recombination: the beginning of the end.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312

• APOBEC3G: an intracellular centurion.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312

• Competitive repair pathways in immunoglobulin gene hypermutation.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312

• Post-translational regulation of activation-induced cytidine deaminase.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312

• Stochastic properties of processive cytidine DNA deaminases AID and APOBEC3G.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312

• Molecular mechanism for generation of antibody memory.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312

• APOBEC proteins and intrinsic resistance to HIV-1 infection.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312

• Powerful mutators lurking in the genome.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312

• Pancreatic cancer: translating lessons from mouse models.

  JOP : Journal of the pancreas 20090309

• Therapeutic tools in pancreatic cancer.

  JOP : Journal of the pancreas 20090309

• DNA hairpins containing the cytidine analog pyrrolo-dC: structural, thermodynamic, and spectroscopic studies.

  Biophysical journal 20090304

• Phosphorothioation of oligonucleotides strongly influences the inhibition of bacterial (M.HhaI) and human (Dnmt1) DNA methyltransferases.

  Chembiochem : a European journal of chemical biology 20090302

• Development of selective agonists and antagonists of P2Y receptors.

  Purinergic signalling 20090301

• Epigenetic regulation of human buccal mucosa mitochondrial superoxide dismutase gene expression by diet.

  The British journal of nutrition 20090301

• Medium-dependent interactions of quinones with cytosine and cytidine: a laser flash photolysis study with magnetic field effect.

  Biophysical chemistry 20090301

• Synthesis and evaluation of novel phosphoramidate prodrugs of 2'-methyl cytidine as inhibitors of hepatitis C virus NS5B polymerase.

  Bioorganic & medicinal chemistry letters 20090301

• Cyclopentenyl cytosine has biological and anti-tumour activity, but does not enhance the efficacy of gemcitabine and radiation in two animal tumour models.

  International journal of oncology 20090301

• The SET complex acts as a barrier to autointegration of HIV-1.

  PLoS pathogens 20090301

• RNA-dependent oligomerization of APOBEC3G is required for restriction of HIV-1.

  PLoS pathogens 20090301

• Reassessing the role of APOBEC3G in human immunodeficiency virus type 1 infection of quiescent CD4+ T-cells.

  PLoS pathogens 20090301

• Restricting activation-induced cytidine deaminase tumorigenic activity in B lymphocytes.

  Immunology 20090301

• The expression of activation induced cytidine deaminase in follicular lymphoma is independent of prognosis and stage.

  Histopathology 20090301

• Biomedical discovery acceleration, with applications to craniofacial development.

  PLoS computational biology 20090301

• Citicoline protects against cognitive impairment in a rat model of chronic cerebral hypoperfusion.

  Journal of clinical neurology (Seoul, Korea) 20090301

• [Determination of cytidine and adenosine in cordyceps by monolithiccapillary electrochromatography].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090301

• Species-specific inhibition of APOBEC3C by the prototype foamy virus protein bet.

  The Journal of biological chemistry 20090227

• Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice.

  Proceedings of the National Academy of Sciences of the United States of America 20090224

• Antibodies to myelin oligodendrocyte glycoprotein are not involved in the severity of chronic non-remitting experimental autoimmune encephalomyelitis.

  Immunology letters 20090221

• Cytosine arabinoside-induced cytogenotoxicity in bone marrow and spermatogonial cells of mice and its potential transmission through the male germline.

  Mutation research 20090219

• AID splice variants lack deaminase activity.

  Blood 20090219

• Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G.

  The EMBO journal 20090218

• Mucosal immunization in macaques upregulates the innate APOBEC 3G anti-viral factor in CD4(+) memory T cells.

  Vaccine 20090205

• Making sense of a missense mutation: characterization of MutT2, a Nudix hydrolase from Mycobacterium tuberculosis, and the G58R mutant encoded in W-Beijing strains of M. tuberculosis.

  Biochemistry 20090203

• Oxidation and glycolytic cleavage of etheno and propano DNA base adducts.

  Biochemistry 20090203

• Toward understanding the conformational dynamics of RNA ligation.

  Biochemistry 20090203

• Inhibition of cytidine deaminase by zebularine enhances the antineoplastic action of 5-aza-2'-deoxycytidine.

  Cancer chemotherapy and pharmacology 20090201

• Augmentation of antibody responses by retinoic acid and costimulatory molecules.

  Seminars in immunology 20090201

• Effective, homogeneous and transient interference with cytosine methylation in plant genomic DNA by zebularine.

  The Plant journal : for cell and molecular biology 20090201

• Epigenetic mechanisms in mammals.

  Cellular and molecular life sciences : CMLS 20090201

• Cytidine deaminase genotype and toxicity of cytosine arabinoside therapy in children with acute myeloid leukemia.

  British journal of haematology 20090201

• Evasion from CypA- and APOBEC-mediated restrictions is insufficient for HIV-1 to efficiently grow in simian cells.

  Microbes and infection 20090201

• Molecular responses of Lotus japonicus to parasitism by the compatible species Orobanche aegyptiaca and the incompatible species Striga hermonthica.

  Journal of experimental botany 20090201

• Lupus-prone MRL/faslpr/lpr mice display increased AID expression and extensive DNA lesions, comprising deletions and insertions, in the immunoglobulin locus: concurrent upregulation of somatic hypermutation and class switch DNA recombination.

  Autoimmunity 20090201

• Differences in APOBEC3G expression in CD4+ T helper lymphocyte subtypes modulate HIV-1 infectivity.

  PLoS pathogens 20090201

• Bacteroides induce higher IgA production than Lactobacillus by increasing activation-induced cytidine deaminase expression in B cells in murine Peyer's patches.

  Bioscience, biotechnology, and biochemistry 20090201

• A genome-scale metabolic reconstruction of Mycoplasma genitalium, iPS189.

  PLoS computational biology 20090201

• Synthesis and hybridization properties of modified oligodeoxynucleotides carrying non-natural bases.

  Chemistry & biodiversity 20090201

• Capecitabine, oxaliplatin and radiotherapy: a phase IB neoadjuvant study for esophageal cancer with gene expression analysis.

  Cancer investigation 20090201

• Molecular evolution of a viral non-coding sequence under the selective pressure of amiRNA-mediated silencing.

  PLoS pathogens 20090201

• A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.

  Oncogene 20090129

• Structure of the nucleotide radical formed during reaction of CDP/TTP with the E441Q-alpha2beta2 of E. coli ribonucleotide reductase.

  Journal of the American Chemical Society 20090114

• Murine APOBEC1 is a powerful mutator of retroviral and cellular RNA in vitro and in vivo.

  Journal of molecular biology 20090109

• Expression and regulation of antiviral protein APOBEC3G in human neuronal cells.

  Journal of neuroimmunology 20090103

• Cloning and pharmacological characterization of a novel gene encoding human nucleoside transporter 1 (hNT1) from a human breast cancer cDNA library.

  Life sciences 20090102

• C-terminal half of HIV-1 Vif C possesses major determinant for APOBEC3G degradation.

  AIDS (London, England) 20090102

• Distribution of gemcitabine pathway genotypes in ethnic Asians and their association with outcome in non-small cell lung cancer patients.

  Lung cancer (Amsterdam, Netherlands) 20090101

• Activation-induced deaminase heterozygous MRL/lpr mice are delayed in the production of high-affinity pathogenic antibodies and in the development of lupus nephritis.

  Immunology 20090101

• Transcriptional pausing and stalling causes multiple clustered mutations by human activation-induced deaminase.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090101

• A reliable confirmation of the chemical structure of synthetic oligonucleotides: detection of active protons in DNA oligomers by low-temperature FT infrared spectroscopy.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090101

• Sole copy of Z2-type human cytidine deaminase APOBEC3H has inhibitory activity against retrotransposons and HIV-1.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090101

• Interleukin-21 stimulates B-cell immunoglobulin E synthesis in human beings concomitantly with activation-induced cytidine deaminase expression and differentiation into plasma cells.

  Human immunology 20090101

• Elite control of HIV infection: implications for vaccine design.

  Expert opinion on biological therapy 20090101

• Pharmacogenomics of gemcitabine in non-small-cell lung cancer and other solid tumors.

  Pharmacogenomics 20090101

• MDM2 is a novel E3 ligase for HIV-1 Vif.

  Retrovirology 20090101

• A cis-acting diversification activator both necessary and sufficient for AID-mediated hypermutation.

  PLoS genetics 20090101

• Human concentrative nucleoside transporter 1-mediated uptake of 5-azacytidine enhances DNA demethylation.

  Molecular cancer therapeutics 20090101

• Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synovium.

  PLoS medicine 20090101

• Autoimmune responses in the rheumatoid synovium.

  PLoS medicine 20090101

• Novel exon of mammalian ADAR2 extends open reading frame.

  PloS one 20090101

• Genetic editing of HBV DNA by monodomain human APOBEC3 cytidine deaminases and the recombinant nature of APOBEC3G.

  PloS one 20090101

• Analysis of small nucleolar RNAs reveals unique genetic features in malaria parasites.

  BMC genomics 20090101

• APOBEC3G induces a hypermutation gradient: purifying selection at multiple steps during HIV-1 replication results in levels of G-to-A mutations that are high in DNA, intermediate in cellular viral RNA, and low in virion RNA.

  Retrovirology 20090101

• DNA targets of AID evolutionary link between antibody somatic hypermutation and class switch recombination.

  Advances in immunology 20090101

• Updates in Gastrointestinal Oncology - insights from the 2008 44th annual meeting of the American Society of Clinical Oncology.

  Journal of hematology & oncology 20090101

• Rapid and widely disseminated acute phase protein response after experimental bacterial infection of pigs.

  Veterinary research 20090101

• APOBEC3G mRNA expression in exposed seronegative and early stage HIV infected individuals decreases with removal of exposure and with disease progression.

  Retrovirology 20090101

• Genes of cell-cell interactions, chemotherapy detoxification and apoptosis are induced during chemotherapy of acute myeloid leukemia.

  BMC cancer 20090101

• Helicobacter pylori and gastric carcinogenesis.

  Journal of gastroenterology 20090101

• Suppression of HIV-1 replication by microRNA effectors.

  Retrovirology 20090101

• Folding machineries displayed on a cation-exchanger for the concerted refolding of cysteine- or proline-rich proteins.

  BMC biotechnology 20090101

• Radiosynthesis of F-18 labeled cytidine analog 2'-fluoro-5-iodo-l-beta-d-arabinofuranosylcytosine ([(18)F]FIAC).

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20090101

• Characterisation of the paralytic shellfish toxin biosynthesis gene clusters in Anabaena circinalis AWQC131C and Aphanizomenon sp. NH-5.

  BMC biochemistry 20090101

• CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells.

  PloS one 20090101

• A novel HIV-1 restriction factor that is biologically distinct from APOBEC3 cytidine deaminases in a human T cell line CEM.NKR.

  Retrovirology 20090101

• Prediction of breast cancer by profiling of urinary RNA metabolites using Support Vector Machine-based feature selection.

  BMC cancer 20090101

• High level expression of the anti-retroviral protein APOBEC3G is induced by influenza A virus but does not confer antiviral activity.

  Retrovirology 20090101

• Comparative study of the persistence of anti-HIV activity of deoxynucleoside HIV reverse transcriptase inhibitors after removal from culture.

  AIDS research and therapy 20090101

• Basic science summary.

  Topics in HIV medicine : a publication of the International AIDS Society, USA 20090101

• Both strands of siRNA have potential to guide posttranscriptional gene silencing in mammalian cells.

  PloS one 20090101

• CD27(-) B-cells produce class switched and somatically hyper-mutated antibodies during chronic HIV-1 infection.

  PloS one 20090101

• CURE-Chloroplast: a chloroplast C-to-U RNA editing predictor for seed plants.

  BMC bioinformatics 20090101

• The combination effect of sodium butyrate and 5-Aza-2'-deoxycytidine on radiosensitivity in RKO colorectal cancer and MCF-7 breast cancer cell lines.

  World journal of surgical oncology 20090101

• High mutability of the tumor suppressor genes RASSF1 and RBSP3 (CTDSPL) in cancer.

  PloS one 20090101

• Dynamic regulation of RNA editing of ion channels and receptors in the mammalian nervous system.

  Molecular brain 20090101

• Origin of saxitoxin biosynthetic genes in cyanobacteria.

  PloS one 20090101

• Intracellular interactions between APOBEC3G, RNA, and HIV-1 Gag: APOBEC3G multimerization is dependent on its association with RNA.

  Retrovirology 20090101

• Paclitaxel alters the expression and specific activity of deoxycytidine kinase and cytidine deaminase in non-small cell lung cancer cell lines.

  Journal of experimental & clinical cancer research : CR 20090101

• [Uracil in DNA--friend or foe?].

  Postepy biochemii 20090101

• Clinical pharmacology and pharmacogenetics of gemcitabine.

  Drug metabolism reviews 20090101

• Transcriptomes and pathways associated with infectivity, survival and immunogenicity in Brugia malayi L3.

  BMC genomics 20090101

• Gemcitabine sensitivity-related mRNA expression in endoscopic ultrasound-guided fine-needle aspiration biopsy of unresectable pancreatic cancer.

  Journal of experimental & clinical cancer research : CR 20090101

• A method for identifying alternative or cryptic donor splice sites within gene and mRNA sequences. Comparisons among sequences from vertebrates, echinoderms and other groups.

  BMC genomics 20090101

• Hydrogen bonding and packing density are factors most strongly connected to limiting sites of high flexibility in the 16S rRNA in the 30S ribosome.

  BMC structural biology 20090101

• Pinellia ternata, Citrus reticulata, and their combinational prescription inhibit eosinophil infiltration and airway hyperresponsiveness by suppressing CCR3+ and Th2 cytokines production in the ovalbumin-induced asthma model.

  Mediators of inflammation 20090101

• Genome-wide profile of pleural mesothelioma versus parietal and visceral pleura: the emerging gene portrait of the mesothelioma phenotype.

  PloS one 20090101

• APOBEC3G-depleted resting CD4+ T cells remain refractory to HIV1 infection.

  PloS one 20090101

• Antiviral roles of APOBEC proteins against HIV-1 and suppression by Vif.

  Archives of virology 20090101

• CAPIH: a Web interface for comparative analyses and visualization of host-HIV protein-protein interactions.

  BMC microbiology 20090101

• Equilibrium and kinetic investigations of the interaction of model platinum(II) complex with DNA constituents in reference to the antitumour activity: complex-formation reactions of [Pd(N,N-diethylethylenediamine)(H2O)2]2+ with ligands of biological significance and displacement reactions of DNA constituents.

  Bioinorganic chemistry and applications 20090101

• Identification of genes responsive to solar simulated UV radiation in human monocyte-derived dendritic cells.

  PloS one 20090101

• Selective deletion of the A1 adenosine receptor abolishes heart-rate slowing effects of intravascular adenosine in vivo.

  PloS one 20090101

• Resistance gene expression determines the in vitro chemosensitivity of non-small cell lung cancer (NSCLC).

  BMC cancer 20090101

• [Mechanisms of interaction between HIV and Mycoplasma arginini in vitro].

  Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20090101

• Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance.

  Journal of translational medicine 20090101

• Insulin gene expression is regulated by DNA methylation.

  PloS one 20090101

• Structure and real-time monitoring of the enzymatic reaction of APOBEC3G which is involved in anti-HIV activity.

  Nucleic acids symposium series (2004) 20090101

• Molecular mechanisms of apoptosis induced by 3'-ethynylcytidine.

  Nucleic acids symposium series (2004) 20090101

• Human cellular restriction factors that target HIV-1 replication.

  BMC medicine 20090101

• FGF4 independent derivation of trophoblast stem cells from the common vole.

  PloS one 20090101

• ERG-associated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage.

  Epigenetics & chromatin 20090101

• Different responses to two types of 5-fluorouracil prodrugs in combination with interferon-alpha in pulmonary metastases of renal cell carcinoma: a case report.

  Cases journal 20090101

• Post-transcriptional control of chloroplast gene expression.

  Gene regulation and systems biology 20090101

• Human APOBEC1 cytidine deaminase edits HBV DNA.

  Retrovirology 20090101

• RAD51 paralogs promote homology-directed repair at diversifying immunoglobulin V regions.

  BMC molecular biology 20090101

• Reciprocal t(9;22) ABL/BCR fusion proteins: leukemogenic potential and effects on B cell commitment.

  PloS one 20090101

• Encapsidation of APOBEC3G into HIV-1 virions involves lipid raft association and does not correlate with APOBEC3G oligomerization.

  Retrovirology 20090101

• Gemcitabine and arabinosylcytosin pharmacogenomics: genome-wide association and drug response biomarkers.

  PloS one 20090101

• The charge-transfer band of an oxidized watson-crick guanosine-cytidine complex.

  Angewandte Chemie (International ed. in English) 20090101

• Azacitidine: a review of its use in higher-risk myelodysplastic syndromes/acute myeloid leukaemia.

  Drugs 20090101

• Activation of adenosine A2B receptors enhances ciliary beat frequency in mouse lateral ventricle ependymal cells.

  Cerebrospinal fluid research 20090101

• Tackling the methylome: recent methodological advances in genome-wide methylation profiling.

  Genome medicine 20090101

• Assessment of Damage to Nucleic Acids and Repair Machinery in Salmonella typhimurium Exposed to Chlorine.

  International journal of microbiology 20090101

• Glycine Receptors Caught between Genome and Proteome - Functional Implications of RNA Editing and Splicing.

  Frontiers in molecular neuroscience 20090101

• Evidence for ADAR-induced hypermutation of the Drosophila sigma virus (Rhabdoviridae).

  BMC genetics 20090101

• Genome-wide identification of Schistosoma japonicum microRNAs using a deep-sequencing approach.

  PloS one 20090101

• Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage.

  Retrovirology 20090101

• Ethnic differences of two non-synonymous single nucleotide polymorphisms in CDA gene.

  Drug metabolism and pharmacokinetics 20090101

• A docking model of human ribonucleotide reductase with flavin and phenosafranine.

  Bioinformation 20090101

• Targeting cancers in the gastrointestinal tract: role of capecitabine.

  OncoTargets and therapy 20090101

• Gemcitabine for the treatment of advanced nonsmall cell lung cancer.

  OncoTargets and therapy 20090101

• Ubiquitous antisense transcription in eukaryotes: novel regulatory mechanism or byproduct of opportunistic RNA polymerase?

  F1000 biology reports 20090101

• The role of azacitidine in the management of myelodysplastic syndromes (MDS).

  Cancer management and research 20090101

• Assessment of the Potential Role of Tryptophan as the Precursor of Serotonin and Melatonin for the Aged Sleep-wake Cycle and Immune Function: Streptopelia Risoria as a Model.

  International journal of tryptophan research : IJTR 20090101

• DNA Cytosine demethylation: are we getting close?

  Cell 20081226

• DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45.

  Cell 20081226

• A conserved DYW domain of the pentatricopeptide repeat protein possesses a novel endoribonuclease activity.

  FEBS letters 20081224

• Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression.

  International journal of cancer 20081215

• Simultaneous determination of nucleobases, nucleosides and saponins in Panax notoginseng using multiple columns high performance liquid chromatography.

  Journal of pharmaceutical and biomedical analysis 20081215

• Sequence variations in 185/333 messages from the purple sea urchin suggest posttranscriptional modifications to increase immune diversity.

  Journal of immunology (Baltimore, Md. : 1950) 20081215

• Collateral damage from antigen receptor gene diversification.

  Cell 20081212

• AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations.

  Cell 20081212

• Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity.

  Cell 20081212

• Activation of p16 gene silenced by DNA methylation in cancer cells by phosphoramidate derivatives of 2'-deoxyzebularine.

  Journal of medicinal chemistry 20081211

• Quantitative analysis of the experimental cytotoxic drug cyclopentenyl cytosine and its metabolite in plasma with HPLC tandem mass spectrometry.

  Biomedical chromatography : BMC 20081201

• Treatment of Venezuelan equine encephalitis virus infection with (-)-carbodine.

  Antiviral research 20081201

• Alternative splicing regulates activation-induced cytidine deaminase (AID): implications for suppression of AID mutagenic activity in normal and malignant B cells.

  Blood 20081201

• Differential allelic expression in leukoblast from patients with acute myeloid leukemia suggests genetic regulation of CDA, DCK, NT5C2, NT5C3, and TP53.

  Drug metabolism and disposition: the biological fate of chemicals 20081201

• Expression of activation-induced cytidine deaminase in malignant lymphomas infiltrating the bone marrow.

  Applied immunohistochemistry & molecular morphology : AIMM 20081201

• Novel targets for HIV therapy.

  Antiviral research 20081201

• Effect of acetylcholine precursors on proliferation and differentiation of astroglial cells in primary cultures.

  Neurochemical research 20081201

• Restriction of retroviral replication by APOBEC3G/F and TRIM5alpha.

  Trends in microbiology 20081201

• Ground state, intermediate, and multivalent nucleotide analogue inhibitors of cytidine 5'-triphosphate synthase.

  ChemMedChem 20081201

• Study on disulfur-backboned nucleic acids: part 3. Efficient synthesis of 3',5'-dithio-2'-deoxyuridine and deoxycytidine.

  Nucleosides, nucleotides & nucleic acids 20081201

• An activation-induced cytidine deaminase-independent mechanism of secondary VH gene rearrangement in preimmune human B cells.

  Journal of immunology (Baltimore, Md. : 1950) 20081201

• Online immobilized metal affinity chromatography/mass spectrometric analysis of changes elicited by cCMP in the murine brain phosphoproteome.

  Rapid communications in mass spectrometry : RCM 20081201

• Phosphorylation of nucleosides and nucleotides with inorganic monoimido-cyclo-triphosphate.

  Chemical & pharmaceutical bulletin 20081201

• Candidate new species of Kobuvirus in porcine hosts.

  Emerging infectious diseases 20081201

• APOBEC3G inhibits elongation of HIV-1 reverse transcripts.

  PLoS pathogens 20081201

• Spt2p defines a new transcription-dependent gross chromosomal rearrangement pathway.

  PLoS genetics 20081201

• Treatment of lymphomatous and leukemic meningitis with liposomal encapsulated cytarabine.

  International journal of nanomedicine 20081201

• APOBEC3G subunits self-associate via the C-terminal deaminase domain.

  The Journal of biological chemistry 20081128

• Effect of the cyclobutane cytidine dimer on the properties of Escherichia coli DNA photolyase.

  The journal of physical chemistry. B 20081127

• Effects of cytidine 5'-diphosphocholine (CDP-choline) on the thermal nociceptive threshold in streptozotocin-induced diabetic mice.

  European journal of pharmacology 20081119

• Self-assembly of a chiral carbonate- and cytidine-containing dodecanuclear copper(II) complex: a multiarm-supplied globular capsule.

  Inorganic chemistry 20081117

• Iron-mediated aggregation and a localized structural change characterize ferritin from a mutant light chain polypeptide that causes neurodegeneration.

  The Journal of biological chemistry 20081114

• Identification and characterization of the nuclear isoform of Drosophila melanogaster CTP:phosphocholine cytidylyltransferase.

  Biochemistry 20081111

• Length of the hypermutation motif DGYW/WRCH in the focus of statistical limits. Implications for a double-motif or extended motif recognition models.

  Journal of theoretical biology 20081107

• Furanose dynamics in the HhaI methyltransferase target DNA studied by solution and solid-state NMR relaxation.

  The journal of physical chemistry. B 20081106

• Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.

  Nature 20081106

• AID- and Ung-dependent generation of staggered double-strand DNA breaks in immunoglobulin class switch DNA recombination: a post-cleavage role for AID.

  Molecular immunology 20081101

• Mouse APOBEC3 restricts friend leukemia virus infection and pathogenesis in vivo.

  Journal of virology 20081101

• Single-strand DNA breaks in Ig class switch recombination that depend on UNG but not AID.

  International immunology 20081101

• Squalenoyl nanomedicine of gemcitabine is more potent after oral administration in leukemia-bearing rats: study of mechanisms.

  Anti-cancer drugs 20081101

• Phosphorylation of APOBEC3G by protein kinase A regulates its interaction with HIV-1 Vif.

  Nature structural & molecular biology 20081101

• Update on antiviral treatment of adenoviral ocular infections.

  American journal of ophthalmology 20081101

• Broadening of neutralization activity to directly block a dominant antibody-driven SARS-coronavirus evolution pathway.

  PLoS pathogens 20081101

• Small RNAs with 5'-polyphosphate termini associate with a Piwi-related protein and regulate gene expression in the single-celled eukaryote Entamoeba histolytica.

  PLoS pathogens 20081101

• Evolution of phosphorylation-dependent regulation of activation-induced cytidine deaminase.

  Molecular cell 20081024

• A systems biology analysis of protein-protein interactions in the APOBEC family.

  Life sciences 20081010

• Enhanced cancer cell growth inhibition by dipeptide prodrugs of floxuridine: increased transporter affinity and metabolic stability.

  Molecular pharmaceutics 20081006

• Synergy of Irofulven in combination with various anti-metabolites, enzyme inhibitors, and miscellaneous agents in MV522 lung carcinoma cells: marked interaction with gemcitabine and 5-fluorouracil.

  Investigational new drugs 20081001

• The expression of 16 genes related to the cell of origin and immune response predicts survival in elderly patients with diffuse large B-cell lymphoma treated with CHOP and rituximab.

  Leukemia 20081001

• Absence of hyperlipidemia in LDL receptor-deficient mice having apolipoprotein B100 without the putative receptor-binding sequences.

  Arteriosclerosis, thrombosis, and vascular biology 20081001

• Characteristics and prediction of RNA editing sites in transcripts of the Moss Takakia lepidozioides chloroplast.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20081001

• The 9-1-1 DNA clamp is required for immunoglobulin gene conversion.

  Molecular and cellular biology 20081001

• Bacterial CMP-sialic acid synthetases: production, properties, and applications.

  Applied microbiology and biotechnology 20081001

• Pyrrolo-C as a molecular probe for monitoring conformations of the tRNA 3' end.

  RNA (New York, N.Y.) 20081001

• Conformational preferences of hypermodified nucleoside lysidine (k2C) occurring at 'wobble' position in anticodon loop of tRNA(Ile).

  Nucleosides, nucleotides & nucleic acids 20081001

• Synthesis and solution conformation studies of the modified nucleoside N(4),2'-O-dimethylcytidine (m(4)Cm) and its analogues.

  Bioorganic & medicinal chemistry 20081001

• Small-molecule inhibition of HIV-1 Vif.

  Nature biotechnology 20081001

• Hypermutation by intersegmental transfer of APOBEC3G cytidine deaminase.

  Nature structural & molecular biology 20081001

• Enhancing immunity to HIV through APOBEC.

  Nature biotechnology 20081001

• The level of APOBEC3G (hA3G)-related G-to-A mutations does not correlate with viral load in HIV type 1-infected individuals.

  AIDS research and human retroviruses 20081001

• Evidence for restriction of ancient primate gammaretroviruses by APOBEC3 but not TRIM5alpha proteins.

  PLoS pathogens 20081001

• Mutation of the zebrafish nucleoporin elys sensitizes tissue progenitors to replication stress.

  PLoS genetics 20081001

• Genetic or pharmaceutical blockade of p110delta phosphoinositide 3-kinase enhances IgE production.

  The Journal of allergy and clinical immunology 20081001

• APOBEC3G-independent reduction in virion infectivity during long-term HIV-1 replication in terminally differentiated macrophages.

  Virology 20080930

• miR-181b negatively regulates activation-induced cytidine deaminase in B cells.

  The Journal of experimental medicine 20080929

• Functional domain organization of human APOBEC3G.

  Virology 20080915

• Characterization of conserved motifs in HIV-1 Vif required for APOBEC3G and APOBEC3F interaction.

  Journal of molecular biology 20080912

• Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection.

  Science (New York, N.Y.) 20080905

• Regulating antibody diversity: taming a mutagen.

  Molecular cell 20080905

• Kinetics and activation parameter analysis for the prebiotic oligocytidylate formation on Na(+)-montmorillonite at 0-100 degrees C.

  The journal of physical chemistry. A 20080904

• Ex vivo chemosensitivity testing and gene expression profiling predict response towards adjuvant gemcitabine treatment in pancreatic cancer.

  British journal of cancer 20080902

• Polymorphism C3435T of the MDR1 gene in Central Americans and Spaniards.

  Molecular biology reports 20080901

• Multifunctionality of Campylobacter jejuni sialyltransferase CstII: characterization of GD3/GT3 oligosaccharide synthase, GD3 oligosaccharide sialidase, and trans-sialidase activities.

  Glycobiology 20080901

• S(mu) mutation patterns suggest different progression pathways in follicular lymphoma: early direct or late from FL progenitor cells.

  Blood 20080901

• Central choline suppresses plasma renin response to graded haemorrhage in rats.

  Clinical and experimental pharmacology & physiology 20080901

• Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer.

  Human molecular genetics 20080901

• A pilot pharmacokinetic study of oral azacitidine.

  Leukemia 20080901

• Gemcitabine pharmacogenomics: deoxycytidine kinase and cytidylate kinase gene resequencing and functional genomics.

  Drug metabolism and disposition: the biological fate of chemicals 20080901

• Conserved footprints of APOBEC3G on Hypermutated human immunodeficiency virus type 1 and human endogenous retrovirus HERV-K(HML2) sequences.

  Journal of virology 20080901

• Hypermutation of an ancient human retrovirus by APOBEC3G.

  Journal of virology 20080901

• Role of phosphatidylglycerol in the function and assembly of Photosystem II reaction center, studied in a cdsA-inactivated PAL mutant strain of Synechocystis sp. PCC6803 that lacks phycobilisomes.

  Biochimica et biophysica acta 20080901

• Absence of H186R polymorphism in exon 4 of the APOBEC3G gene among North Indian individuals.

  Genetic testing 20080901

• Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers.

  Gastroenterology 20080901

• Inflammation and cancer: is AID aiding?

  Gastroenterology 20080901

• [Quantitative analysis of nucleotide mixtures with terahertz time domain spectroscopy].

  Guang pu xue yu guang pu fen xi = Guang pu 20080901

• Cancer prevention: epigenetics steps up to the plate.

  Cancer prevention research (Philadelphia, Pa.) 20080901

• Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice.

  Cancer prevention research (Philadelphia, Pa.) 20080901

• Historical survey on chromatoid body research.

  Acta histochemica et cytochemica 20080828

• Determination of nucleotides in infant formula by ion-exchange liquid chromatography.

  Journal of agricultural and food chemistry 20080827

• Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1.

  Molecular cell 20080822

• A new entry to carbocyclic nucleosides: oxidative coupling reaction of cycloalkenylsilanes with a nucleobase mediated by hypervalent iodine reagent.

  Organic letters 20080821

• The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon.

  The EMBO journal 20080820

• The incorporation of APOBEC3 proteins into murine leukemia viruses.

  Virology 20080815

• Relationship between human immunodeficiency type 1 infection and expression of human APOBEC3G and APOBEC3F.

  The Journal of infectious diseases 20080815

• Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut.

  Immunity 20080815

• Cytidine-5-diphosphocholine supplement in early life induces stable increase in dendritic complexity of neurons in the somatosensory cortex of adult rats.

  Neuroscience 20080813

• AID and RAG1 do not contribute to lymphomagenesis in Emu c-myc transgenic mice.

  Oncogene 20080807

• Interstrand cross-link formation in duplex and triplex DNA by modified pyrimidines.

  Journal of the American Chemical Society 20080806

• Plasma pharmacokinetics and oral bioavailability of 3,4,5,6-tetrahydrouridine, a cytidine deaminase inhibitor, in mice.

  Cancer chemotherapy and pharmacology 20080801

• Conserved and non-conserved features of HIV-1 and SIVagm Vif mediated suppression of APOBEC3 cytidine deaminases.

  Cellular microbiology 20080801

• Effects of prenatal tobacco exposure on gene expression profiling in umbilical cord tissue.

  Pediatric research 20080801

• Insights into cellular microRNAs and human immunodeficiency virus type 1 (HIV-1).

  Journal of cellular physiology 20080801

• The iscS gene deficiency affects the expression of pyrimidine metabolism genes.

  Biochemical and biophysical research communications 20080801

• Dihydropyrimidine dehydrogenases and cytidine-deaminase gene polymorphisms as outcome predictors in resected gastric cancer patients treated with fluoropyrimidine adjuvant chemotherapy.

  Journal of surgical oncology 20080801

• Robust antiviral activity of R1626, a novel nucleoside analog: a randomized, placebo-controlled study in patients with chronic hepatitis C.

  Hepatology (Baltimore, Md.) 20080801

• Mass spectrometry of protein-ligand complexes: enhanced gas-phase stability of ribonuclease-nucleotide complexes.

  Journal of the American Society for Mass Spectrometry 20080801

• R1626 plus peginterferon Alfa-2a provides potent suppression of hepatitis C virus RNA and significant antiviral synergy in combination with ribavirin.

  Hepatology (Baltimore, Md.) 20080801

• Hepatic lipase gene -514C/T polymorphism in the Guangxi Hei Yi Zhuang and Han populations.

  Lipids 20080801

• Identification of initiator B cells, a novel subset of activation-induced deaminase-dependent B-1-like cells that mediate initiation of contact sensitivity.

  Journal of immunology (Baltimore, Md. : 1950) 20080801

• 13C relaxation studies of the DNA target sequence for hhai methyltransferase reveal unique motional properties.

  Biochemistry 20080722

• Stereoselective synthesis of 4'-selenonucleosides using the Pummerer glycosylation reaction.

  Carbohydrate research 20080721

• Distinct viral determinants for the packaging of human cytidine deaminases APOBEC3G and APOBEC3C.

  Virology 20080720

• The HIV-1 Vif PPLP motif is necessary for human APOBEC3G binding and degradation.

  Virology 20080720

• Characterization of Ig gene somatic hypermutation in the absence of activation-induced cytidine deaminase.

  Journal of immunology (Baltimore, Md. : 1950) 20080715

• Artificial DNA made exclusively of nonnatural C-nucleosides with four types of nonnatural bases.

  Journal of the American Chemical Society 20080709

• Concentrations of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine (FdCyd) and its cytotoxic metabolites in plasma of patients treated with FdCyd and tetrahydrouridine (THU).

  Cancer chemotherapy and pharmacology 20080701

• Optimized blood sampling with cytidine deaminase inhibitor for improved analysis of capecitabine metabolites.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080701

• Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF.

  Journal of immunology (Baltimore, Md. : 1950) 20080701

• Induction of nucleoside phosphorylase in Enterobacter aerogenes and enzymatic synthesis of adenine arabinoside.

  Journal of Zhejiang University. Science. B 20080701

• APOBEC3G and APOBEC3F require an endogenous cofactor to block HIV-1 replication.

  PLoS pathogens 20080701

• Physicochemical properties of the nucleoside prodrug R1626 leading to high oral bioavailability.

  Drug development and industrial pharmacy 20080701

• Brevetoxin forms covalent DNA adducts in rat lung following intratracheal exposure.

  Environmental health perspectives 20080701

• [Ethnic differences of genetic polymorphisms in cancer chemotherapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20080701

• [The associations between polymorphisms of APOBEC3G and different outcomes of persistent HBV infection].

  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20080701

• [Advances in the study of molecular mechanism of APOBEC3G anti-HIV-1].

  Yao xue xue bao = Acta pharmaceutica Sinica 20080701

• [Study on the relationship between human cytidine deaminase gene polymorphisms and Ara-C sensitivity].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20080701

• Impact of phosphorylation and phosphorylation-null mutants on the activity and deamination specificity of activation-induced cytidine deaminase.

  The Journal of biological chemistry 20080620

• Variable contexts and levels of hypermutation in HIV-1 proviral genomes recovered from primary peripheral blood mononuclear cells.

  Virology 20080620

• The emerging role of innate immunity in protection against HIV-1 infection.

  Vaccine 20080606

• Not just sheer luck! Immune correlates of protection against HIV-1 infection.

  Vaccine 20080606

• Bisphosphonate derivatives of nucleoside antimetabolites: hydrolytic stability and hydroxyapatite adsorption of 5'-beta,gamma-methylene and 5'-beta,gamma-(1-hydroxyethylidene) triphosphates of 5-fluorouridine and ara-cytidine.

  The Journal of organic chemistry 20080606

• Evolution of HIV-1 isolates that use a novel Vif-independent mechanism to resist restriction by human APOBEC3G.

  Current biology : CB 20080603

• APOBEC3 proteins and reverse transcription.

  Virus research 20080601

• Associations between cigarette smoking and mitochondrial DNA abnormalities in buccal cells.

  Carcinogenesis 20080601

• Acid-base and metal ion binding properties of 2-thiocytidine in aqueous solution.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20080601

• Existence of hepatitis C virus NS5B variants naturally resistant to non-nucleoside, but not to nucleoside, polymerase inhibitors among untreated patients.

  The Journal of antimicrobial chemotherapy 20080601

• Comparison of cellular ribonucleoprotein complexes associated with the APOBEC3F and APOBEC3G antiviral proteins.

  Journal of virology 20080601

• Characterization of Aquifex aeolicus 4-diphosphocytidyl-2C-methyl-d-erythritol kinase - ligand recognition in a template for antimicrobial drug discovery.

  The FEBS journal 20080601

• Clonal relationship between infiltrating immunoglobulin G4 (IgG4)-positive plasma cells in lacrimal glands and circulating IgG4-positive lymphocytes in Mikulicz's disease.

  Clinical and experimental immunology 20080601

• Nucleoside composition of Heloderma venoms.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20080601

• Biosynthesis of the Escherichia coli K1 group 2 polysialic acid capsule occurs within a protected cytoplasmic compartment.

  Molecular microbiology 20080601

• Hepatitis B: modern concepts in pathogenesis--APOBEC3 cytidine deaminases as effectors in innate immunity against the hepatitis B virus.

  Current opinion in infectious diseases 20080601

• Single-stranded RNA facilitates nucleocapsid: APOBEC3G complex formation.

  RNA (New York, N.Y.) 20080601

• Role of phosphatidylcholine biosynthesis in the regulation of lipoprotein homeostasis.

  Current opinion in lipidology 20080601

• Interactions of nucleosides with CrO(4) (2-) and Cr(3+) as studied by electrospray ionization mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20080601

• Metabonomics in cancer diagnosis: mass spectrometry-based profiling of urinary nucleosides from breast cancer patients.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20080601

• Modulation of gemcitabine (2',2'-difluoro-2'-deoxycytidine) pharmacokinetics, metabolism, and bioavailability in mice by 3,4,5,6-tetrahydrouridine.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20080601

• Patterns of evolution and host gene mimicry in influenza and other RNA viruses.

  PLoS pathogens 20080601

• Epigenetic treatment of myelodysplastic syndromes and acute myeloid leukemias.

  Current medicinal chemistry 20080601

• The B cell antigen receptor and overexpression of MYC can cooperate in the genesis of B cell lymphomas.

  PLoS biology 20080601

• Correlation between cytidine deaminase genotype and gemcitabine deamination in blood samples.

  Nucleosides, nucleotides & nucleic acids 20080601

• Key labeling technologies to tackle sizeable problems in RNA structural biology.

  International journal of molecular sciences 20080601

• APOBEC3G restricts early HIV-1 replication in the cytoplasm of target cells.

  Virology 20080525

• A model for oligomeric regulation of APOBEC3G cytosine deaminase-dependent restriction of HIV.

  The Journal of biological chemistry 20080516

• Mutational analysis of conserved glycine residues 142, 143 and 146 reveals Gly(142) is critical for tetramerization of CTP synthase from Escherichia coli.

  The Biochemical journal 20080515

• Crystal structure of an ADP-ribosylated protein with a cytidine deaminase-like fold, but unknown function (TM1506), from Thermotoga maritima at 2.70 A resolution.

  Proteins 20080515

• APOBEC3G is degraded by the proteasomal pathway in a Vif-dependent manner without being polyubiquitylated.

  The Journal of biological chemistry 20080509

• Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila: substrate specificity and requirement for virulence.

  The Journal of biological chemistry 20080509

• Antitumoral activity of PEG-gemcitabine prodrugs targeted by folic acid.

  Journal of controlled release : official journal of the Controlled Release Society 20080508

• Profiling of differentially expressed genes in porcine epithelial cells derived from periodontal ligament and gingiva by DNA microarray.

  Archives of oral biology 20080501

• Human APOBEC3G can restrict retroviral infection in avian cells and acts independently of both UNG and SMUG1.

  Journal of virology 20080501

• The hepatitis C virus replicon presents a higher barrier to resistance to nucleoside analogs than to nonnucleoside polymerase or protease inhibitors.

  Antimicrobial agents and chemotherapy 20080501

• Molecular modeling and dynamics studies of cytidylate kinase from Mycobacterium tuberculosis H37Rv.

  Journal of molecular modeling 20080501

• Reflections on the state of play in somatic hypermutation.

  Molecular immunology 20080501

• Confirmation of the chromosome damaging effects of lamivudine in in vitro human peripheral blood lymphocytes.

  Environmental and molecular mutagenesis 20080501

• Hypermutation of hepatitis B virus genomes by APOBEC3G, APOBEC3C and APOBEC3H.

  The Journal of general virology 20080501

• MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase.

  Immunity 20080501

• Primate lentiviral Vpx commandeers DDB1 to counteract a macrophage restriction.

  PLoS pathogens 20080501

• MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation.

  Immunity 20080501

• A carboxylesterase 2 gene polymorphism as predictor of capecitabine on response and time to progression.

  Current drug metabolism 20080501

• Along came a spider: AID escapes a microRNA web.

  Immunity 20080501

• APOBEC3 proteins and porcine endogenous retroviruses.

  Transplantation proceedings 20080501

• Human cytidine deaminase APOBEC3H restricts HIV-1 replication.

  The Journal of biological chemistry 20080425

• Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells.

  Journal of immunology (Baltimore, Md. : 1950) 20080415

• Comprehensive genetic and epigenetic analysis of occult hepatitis B from liver tissue samples.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080415

• Hypotensive effects of intravenously administered uridine and cytidine in conscious rats: involvement of adenosine receptors.

  European journal of pharmacology 20080414

• Evidence for editing of human papillomavirus DNA by APOBEC3 in benign and precancerous lesions.

  Science (New York, N.Y.) 20080411

• Cyclopentenyl cytosine increases gemcitabine radiosensitisation in human pancreatic cancer cells.

  British journal of cancer 20080408

• Exogenous nucleosides accelerate differentiation of rat intestinal epithelial cells.

  The British journal of nutrition 20080401

• AID-mediated diversification within the IgL locus of chicken DT40 cells is restricted to the transcribed IgL gene.

  Molecular immunology 20080401

• Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney.

  Molecular immunology 20080401

• PI3K is a negative regulator of IgE production.

  International immunology 20080401

• A memoir of AID, which engraves antibody memory on DNA.

  Nature immunology 20080401

• Pyrimidine-specific ribonucleoside hydrolase from the archaeon Sulfolobus solfataricus--biochemical characterization and homology modeling.

  The FEBS journal 20080401

• Vif and Apobec3G in the innate immune response to HIV: a tale of two proteins.

  Future microbiology 20080401

• Response to the methylation inhibitor dihydro-5-azacytidine in mesothelioma is not associated with methylation of p16INK4a: results of cancer and leukemia group B 159904.

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080401

• Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells.

  Leukemia & lymphoma 20080401

• A splenic marginal zone-like peripheral blood CD27+B220- B cell population is preferentially depleted in HIV type 1-infected individuals.

  AIDS research and human retroviruses 20080401

• The role of DNA hypermethylation and demethylation in cancer and cancer therapy.

  Current oncology (Toronto, Ont.) 20080401

• Evolution, development, mechanism and function of IgA in the gut.

  Current opinion in immunology 20080401

• [The assay of intracelluar cytidine deaminase activity and its clinical significance in patient with acute leukemia].

  Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20080401

• 'One pill, once daily': what clinicians need to know about Atriplatrade mark.

  Therapeutics and clinical risk management 20080401

• [Study on the difference of the APOBEC3G mRNA levels among HIV long-term nonprogressors, slow progressors, people at high risks and normal people].

  Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20080401

• [Relationship between the expression of the genes encoding the key enzymes for cytarabine metabolism and the pharmacokinetics of cytarabine in the treatment of childhood acute leukemia with high-dose cytarabine].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20080401

• DNA-labelled cytidine assay for the quantification of CAG repeats.

  Journal of neuroscience methods 20080330

• Sequence editing by Apolipoprotein B RNA-editing catalytic component [corrected] and epidemiological surveillance of transmitted HIV-1 drug resistance.

  AIDS (London, England) 20080330

• Nuclear Exclusion of the HIV-1 host defense factor APOBEC3G requires a novel cytoplasmic retention signal and is not dependent on RNA binding.

  The Journal of biological chemistry 20080321

• Structural insights into mechanisms of catalysis and inhibition in Norwalk virus polymerase.

  The Journal of biological chemistry 20080321

• High-performance liquid chromatography determination of 5-methyl-2'-deoxycytidine, 2'-deoxycytidine, and other deoxynucleosides and nucleosides in DNA digests.

  Analytical biochemistry 20080315

• Correlation of CDA, ERCC1, and XPD polymorphisms with response and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20080315

• Crystal structures of Streptococcus mutans 2'-deoxycytidylate deaminase and its complex with substrate analog and allosteric regulator dCTP x Mg2+.

  Journal of molecular biology 20080314

• Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G.

  Nature 20080306

• Identification of somatic hypermutations in the TP53 gene in B-cell chronic lymphocytic leukemia.

  Molecular immunology 20080301

• Activation-induced deaminase-mediated class switch recombination is blocked by anti-IgM signaling in a phosphatidylinositol 3-kinase-dependent fashion.

  Molecular immunology 20080301

• Germinal center B-cell-associated DNA hypomethylation at transcriptional regions of the AID gene.

  Molecular immunology 20080301

• HIV-1 Vif promotes the formation of high molecular mass APOBEC3G complexes.

  Virology 20080301

• Simultaneous analysis of microbial identity and function using NanoSIMS.

  Environmental microbiology 20080301

• Is AID a monomer in solution?

  DNA repair 20080301

• Conjugation of (E)-5-[2-(Methoxycarbonyl)ethenyl]cytidine to hydrophilic microspheres: development of a mobile microscale UV light actinometer.

  Bioconjugate chemistry 20080301

• APOBEC3G upregulation by alpha interferon restricts human immunodeficiency virus type 1 infection in human peripheral plasmacytoid dendritic cells.

  The Journal of general virology 20080301

• Enhanced NMR signal detection of imino protons in RNA molecules containing 3' dangling nucleotides.

  Journal of biomolecular NMR 20080301

• Mechanisms for decreased function of B cells in aged mice and humans.

  Journal of immunology (Baltimore, Md. : 1950) 20080301

• Characterization of a temperature-sensitive mutation that impairs the function of yeast tRNA nucleotidyltransferase.

  Yeast (Chichester, England) 20080301

• RNA editing in the anticodon of tRNA Leu (CAA) occurs before group I intron splicing in plastids of a moss Takakia lepidozioides S. Hatt. & Inoue.

  Plant biology (Stuttgart, Germany) 20080301

• Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma.

  Hepatology (Baltimore, Md.) 20080301

• Cytidine deaminases as a weapon against retroviruses and a new target for antiviral therapy.

  Mini reviews in medicinal chemistry 20080301

• GADD45A does not promote DNA demethylation.

  PLoS genetics 20080301

• Selenium derivatization of nucleic acids for phase and structure determination in nucleic acid X-ray crystallography.

  International journal of molecular sciences 20080301

• The epigenetic origin of aneuploidy.

  Current genomics 20080301

• Transition state structure of E. coli tRNA-specific adenosine deaminase.

  Journal of the American Chemical Society 20080227

• Simultaneous determination of decitabine and vorinostat (Suberoylanalide hydroxamic acid, SAHA) by liquid chromatography tandem mass spectrometry for clinical studies.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080215

• Comment on 'Activation-induced cytidine deaminase expression in follicular dendritic cell networks and interfollicular large B cells supports functionality of ectopic lymphoid neogenesis in autoimmune sialoadenitis and MALT lymphoma in Sjogren's syndrome'.

  Journal of immunology (Baltimore, Md. : 1950) 20080215

• Cutting edge: a cis-acting DNA element targets AID-mediated sequence diversification to the chicken Ig light chain gene locus.

  Journal of immunology (Baltimore, Md. : 1950) 20080215

• Two levels of protection for the B cell genome during somatic hypermutation.

  Nature 20080214

• Synthesis and antiviral activities of amide derivatives containing the alpha-aminophosphonate moiety.

  Journal of agricultural and food chemistry 20080213

• Distribution of nucleosides and nucleobases in edible fungi.

  Journal of agricultural and food chemistry 20080213

• Will cyclopentenyl cytosine (CPEC) ever have a future in the clinic?

  Leukemia research 20080201

• Ternary borate-nucleoside complex stabilization by ribonuclease A demonstrates phosphate mimicry.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20080201

• Pathways of pyrimidine salvage in Pseudomonas and former Pseudomonas: detection of recycling enzymes using high-performance liquid chromatography.

  Current microbiology 20080201

• Brca1 in immunoglobulin gene conversion and somatic hypermutation.

  DNA repair 20080201

• Vpr.A3A chimera inhibits HIV replication.

  The Journal of biological chemistry 20080201

• The pyrimidin analogue cyclopentenyl cytosine induces alloantigen-specific non-responsiveness of human T lymphocytes.

  Clinical and experimental immunology 20080201

• Antibody diversification by somatic mutation: from Burnet onwards.

  Immunology and cell biology 20080201

• Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion.

  International immunology 20080201

• Incorporation of zebularine from its 2'-deoxyribonucleoside triphosphate derivative and activity as a template-coding nucleobase.

  Nucleosides, nucleotides & nucleic acids 20080201

• Pharmacokinetics of apricitabine, a novel nucleoside reverse transcriptase inhibitor, in healthy volunteers treated with trimethoprim-sulphamethoxazole.

  Journal of clinical pharmacy and therapeutics 20080201

• The 262T>C silent mutation of the platelet beta 3-integrin gene is not restricted to a single family.

  Transfusion 20080201

• Modeling multiple myeloma by AID-dependent conditional activation of MYC.

  Cancer cell 20080201

• AID-dependent activation of a MYC transgene induces multiple myeloma in a conditional mouse model of post-germinal center malignancies.

  Cancer cell 20080201

• TRIM E3 ligases interfere with early and late stages of the retroviral life cycle.

  PLoS pathogens 20080201

• Nucleotide biosynthesis is critical for growth of bacteria in human blood.

  PLoS pathogens 20080201

• [Enhanced protein production of Vif and APOBEC3G by HIV-1 Vpr].

  Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20080201

• Structural analysis of sialyltransferase PM0188 from Pasteurella multocida complexed with donor analogue and acceptor sugar.

  BMB reports 20080131

• A phase II study of paclitaxel and capecitabine as a first-line combination chemotherapy for advanced gastric cancer.

  British journal of cancer 20080129

• 2'-deoxy-4'-azido nucleoside analogs are highly potent inhibitors of hepatitis C virus replication despite the lack of 2'-alpha-hydroxyl groups.

  The Journal of biological chemistry 20080125

• Structural requirements for the activation of Escherichia coli CTP synthase by the allosteric effector GTP are stringent, but requirements for inhibition are lax.

  The Journal of biological chemistry 20080125

• Interaction with 7SL RNA but not with HIV-1 genomic RNA or P bodies is required for APOBEC3F virion packaging.

  Journal of molecular biology 20080125

• Crystal structure and mutational study of a unique SpoU family archaeal methylase that forms 2'-O-methylcytidine at position 56 of tRNA.

  Journal of molecular biology 20080125

• Peripheral administration of CDP-choline and its cholinergic metabolites increases serum insulin: muscarinic and nicotinic acetylcholine receptors are both involved in their actions.

  Neuroscience letters 20080124

• Synthesis and characterization of poly(2-ethyl 2-oxazoline)-conjugates with proteins and drugs: suitable alternatives to PEG-conjugates?

  Journal of controlled release : official journal of the Controlled Release Society 20080122

• Synthesis and characterization of the 5-methyl-2'-deoxycytidine glycol-dioxoosmium-bipyridine ternary complex in DNA.

  Organic & biomolecular chemistry 20080121

• Characterization of reproduction-specific genes in a marine bivalve mollusc: influence of maturation stage and sex on mRNA expression.

  Gene 20080115

• CpG drives human transitional B cells to terminal differentiation and production of natural antibodies.

  Journal of immunology (Baltimore, Md. : 1950) 20080115

• Novel blood-based, five-gene biomarker set for the detection of colorectal cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20080115

• Reversible sialylation: synthesis of cytidine 5'-monophospho-N-acetylneuraminic acid from cytidine 5'-monophosphate with alpha2,3-sialyl O-glycan-, glycolipid-, and macromolecule-based donors yields diverse sialylated products.

  Biochemistry 20080108

• Function analysis of sequences in human APOBEC3G involved in Vif-mediated degradation.

  Virology 20080105

• Expression of a mutant form of the ferritin light chain gene induces neurodegeneration and iron overload in transgenic mice.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080102

• Molecular genetic analysis of Hungarian patients with the hyper-immunoglobulin M syndrome.

  Molecular immunology 20080101

• Modulation of human cytidine deaminase by specific aminoacids involved in the intersubunit interactions.

  Proteins 20080101

• Cytidine deaminase APOBEC3B interacts with heterogeneous nuclear ribonucleoprotein K and suppresses hepatitis B virus expression.

  Cellular microbiology 20080101

• Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA.

  DNA repair 20080101

• Compartmentalization of non-adenine nucleotides in anoxic cardiac myocytes.

  Basic research in cardiology 20080101

• B-cell receptor cross-linking delays activation-induced cytidine deaminase induction and inhibits class-switch recombination to IgE.

  The Journal of allergy and clinical immunology 20080101

• Why does the gut choose apolipoprotein B48 but not B100 for chylomicron formation?

  American journal of physiology. Gastrointestinal and liver physiology 20080101

• Synthesis and characterization of cytidine derivatives that inhibit the kinase IspE of the non-mevalonate pathway for isoprenoid biosynthesis.

  ChemMedChem 20080101

• AID is required for germinal center-derived lymphomagenesis.

  Nature genetics 20080101

• The extent of DNA deformation in DNA photolyase-substrate complexes: a solution state fluorescence study.

  Photochemistry and photobiology 20080101

• Silencing of GM3 synthase suppresses lung metastasis of murine breast cancer cells.

  Breast cancer research : BCR 20080101

• Biochemical characterization of transporter associated with antigen processing (TAP)-like (ABCB9) expressed in insect cells.

  Biological & pharmaceutical bulletin 20080101

• Protocol for nearly full-length sequencing of HIV-1 RNA from plasma.

  PloS one 20080101

• Cyclic tetranuclear half-sandwich ruthenium(II) complexes with 4,7-phenanthroline and hydroxo bridges: crystal structure, solution behaviour and binding to nucleosides.

  Journal of inorganic biochemistry 20080101

• Dissecting the differences between the alpha and beta anomers of the oxidative DNA lesion FaPydG.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Ectopic expression of AID in a non-B cell line triggers A:T and G:C point mutations in non-replicating episomal vectors.

  PloS one 20080101

• Positive selection and increased antiviral activity associated with the PARP-containing isoform of human zinc-finger antiviral protein.

  PLoS genetics 20080101

• Peripheral administration of CDP-choline, phosphocholine or choline increases plasma adrenaline and noradrenaline concentrations.

  Autonomic & autacoid pharmacology 20080101

• Solubility enhancement of aggregation-prone heterologous proteins by fusion expression using stress-responsive Escherichia coli protein, RpoS.

  BMC biotechnology 20080101

• Pathways of acetylcholine synthesis, transport and release as targets for treatment of adult-onset cognitive dysfunction.

  Current medicinal chemistry 20080101

• Cyclic, trinuclear PdII complex of cytidine with pronounced double cone structure.

  Journal of inorganic biochemistry 20080101

• 6th international symposium on retroviral nucleocapsid.

  Retrovirology 20080101

• Fitness of isogenic colony morphology variants of Pseudomonas aeruginosa in murine airway infection.

  PloS one 20080101

• The biochemistry of somatic hypermutation.

  Annual review of immunology 20080101

• The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements.

  Annual review of immunology 20080101

• Functions, structure, and read-through alternative splicing of feline APOBEC3 genes.

  Genome biology 20080101

• The process of RNA editing in plant mitochondria.

  Mitochondrion 20080101

• Aberrant AID expression and human cancer development.

  The international journal of biochemistry & cell biology 20080101

• Turning up the volume on mutational pressure: is more of a good thing always better? (A case study of HIV-1 Vif and APOBEC3).

  Retrovirology 20080101

• Mechanism and regulation of class switch recombination.

  Annual review of immunology 20080101

• A generic approach to identify Transcription Factor-specific operator motifs; Inferences for LacI-family mediated regulation in Lactobacillus plantarum WCFS1.

  BMC genomics 20080101

• Is plant mitochondrial RNA editing a source of phylogenetic incongruence? An answer from in silico and in vivo data sets.

  BMC bioinformatics 20080101

• Vpr14-88-Apobec3G fusion protein is efficiently incorporated into Vif-positive HIV-1 particles and inhibits viral infection.

  PloS one 20080101

• Separation of cytidine 5'-triphosphate biosynthesized from cytidine 5'-monophosphate on ion-exchange resin and HPLC analysis of cytidine compounds.

  Applied biochemistry and biotechnology 20080101

• Quantitative correlation between promoter methylation and messenger RNA levels of the reduced folate carrier.

  BMC cancer 20080101

• Importance of dose-schedule of 5-aza-2'-deoxycytidine for epigenetic therapy of cancer.

  BMC cancer 20080101

• High-throughput synthesis of HepDirect prodrugs of nucleoside monophosphates.

  Journal of combinatorial chemistry 20080101

• Mouse apolipoprotein B editing complex 3 (APOBEC3) is expressed in germ cells and interacts with dead-end (DND1).

  PloS one 20080101

• Quantitative effect of suboptimal codon usage on translational efficiency of mRNA encoding HIV-1 gag in intact T cells.

  PloS one 20080101

• Uracil within DNA: an actor of antiviral immunity.

  Retrovirology 20080101

• Anticancer drug discovery targeting DNA hypermethylation.

  Current medicinal chemistry 20080101

• Genotyping panel for assessing response to cancer chemotherapy.

  BMC medical genomics 20080101

• Isolation and characterization of side population stem cells in articular synovial tissue.

  BMC musculoskeletal disorders 20080101

• HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells.

  PloS one 20080101

• A regulatory role for NBS1 in strand-specific mutagenesis during somatic hypermutation.

  PloS one 20080101

• A cytosine methyltransferase homologue is essential for sexual development in Aspergillus nidulans.

  PloS one 20080101

• HIV-1 Vif, APOBEC, and intrinsic immunity.

  Retrovirology 20080101

• Characterization of APOBEC3G binding to 7SL RNA.

  Retrovirology 20080101

• APOBEC3G encapsidation into HIV-1 virions: which RNA is it?

  Retrovirology 20080101

• The AID/APOBEC family of nucleic acid mutators.

  Genome biology 20080101

• Identification of amino acid residues in HIV-1 Vif critical for binding and exclusion of APOBEC3G/F.

  Microbes and infection 20080101

• Combinations of 2'-C-methylcytidine analogues with interferon-alpha2b and triple combination with ribavirin in the hepatitis C virus replicon system.

  Antiviral chemistry & chemotherapy 20080101

• Mouse T-cells restrict replication of human immunodeficiency virus at the level of integration.

  Retrovirology 20080101

• Implication of TRIM alpha and TRIMCyp in interferon-induced anti-retroviral restriction activities.

  Retrovirology 20080101

• The Role of PPAR-gamma and Its Interaction with COX-2 in Pancreatic Cancer.

  PPAR research 20080101

• Replication potentials of vif variant viruses generated from monkey cell-tropic HIV-1 derivative clones NL-DT5/NL-DT5R.

  Microbes and infection 20080101

• Host restriction factors blocking retroviral replication.

  Annual review of genetics 20080101

• Direct infection and replication of naturally occurring hepatitis C virus genotypes 1, 2, 3 and 4 in normal human hepatocyte cultures.

  PloS one 20080101

• MSDmotif: exploring protein sites and motifs.

  BMC bioinformatics 20080101

• Demonstration of a novel HIV-1 restriction phenotype from a human T cell line.

  PloS one 20080101

• Evolutionary patterns in the sequence and structure of transfer RNA: a window into early translation and the genetic code.

  PloS one 20080101

• APOBEC3G-UBA2 fusion as a potential strategy for stable expression of APOBEC3G and inhibition of HIV-1 replication.

  Retrovirology 20080101

• Complexes of Cu(II) ions and noncovalent interactions in systems with L-aspartic acid and cytidine-5'-monophosphate.

  Bioinorganic chemistry and applications 20080101

• Complete genome of Phenylobacterium zucineum--a novel facultative intracellular bacterium isolated from human erythroleukemia cell line K562.

  BMC genomics 20080101

• Restriction by APOBEC3 proteins of endogenous retroviruses with an extracellular life cycle: ex vivo effects and in vivo 'traces' on the murine IAPE and human HERV-K elements.

  Retrovirology 20080101

• Dynamic RNA profiling in Plasmodium falciparum synchronized blood stages exposed to lethal doses of artesunate.

  BMC genomics 20080101

• Activation-induced cytidine deaminase deficiency causes organ-specific autoimmune disease.

  PloS one 20080101

• A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: potential impact on CTL epitopes.

  Virology journal 20080101

• NMR assignments and the identification of the secondary structure of the anti-retroviral cytidine deaminase.

  Nucleic acids symposium series (2004) 20080101

• 2'-Methylseleno modified oligoribonucleotides synthesized for X-ray crystallography.

  Nucleic acids symposium series (2004) 20080101

• Synthesis and properties of 2'-modified-4'-thioRNA.

  Nucleic acids symposium series (2004) 20080101

• Synthesis and properties of oligonucleotides containing 4'-selenoribonucleosides.

  Nucleic acids symposium series (2004) 20080101

• Design of an ultimate quencher free molecular beacon containing pyrrolocytidine-guanine base pair.

  Nucleic acids symposium series (2004) 20080101

• Site-specific modification by functionality-transfer oligonucleotide with the photo-inducible reactivity.

  Nucleic acids symposium series (2004) 20080101

• RNA containing pyrrolocytidine base analogs: increased binding affinity and fluorescence that responds to hybridization.

  Nucleic acids symposium series (2004) 20080101

• RNA containing pyrrolocytidine base analogs: good binding affinity and fluorescence that responds to hybridization.

  Nucleic acids symposium series (2004) 20080101

• Total syntheses of a North methanocarba puromycin analog and its dinucleotide derivative.

  Nucleic acids symposium series (2004) 20080101

• Synthesis and antiviral activity of novel derivatives of 2'-beta-C-methylcytidine.

  Nucleic acids symposium series (2004) 20080101

• In vitro activity and mechanism of action of a duplex and multidrug of ethynylcytidine and 5-fluorodeoxyuridine.

  Nucleic acids symposium series (2004) 20080101

• Synthesis of conformationally locked carbocyclic 1,3-diazepinone nucleosides as inhibitors of cytidine deaminase.

  Nucleic acids symposium series (2004) 20080101

• RNomics and Modomics in the halophilic archaea Haloferax volcanii: identification of RNA modification genes.

  BMC genomics 20080101

• Did RNA editing in plant organellar genomes originate under natural selection or through genetic drift?

  Biology direct 20080101

• DNA damage in preserved specimens and tissue samples: a molecular assessment.

  Frontiers in zoology 20080101

• The epigenetics of cancer in children.

  Klinische Padiatrie 20080101

• High-fidelity correction of genomic uracil by human mismatch repair activities.

  BMC molecular biology 20080101

• A systematic approach to understand the mechanism of action of the bisthiazolium compound T4 on the human malaria parasite, Plasmodium falciparum.

  BMC genomics 20080101

• Gender differences in genetic risk profiles for cardiovascular disease.

  PloS one 20080101

• Comparing methods of detection and quantitation of RNA editing of rat glycine receptor alpha3.

  International journal of biological sciences 20080101

• 25 years of HIV-1 research - progress and perspectives.

  BMC medicine 20080101

• Antitumor efficacy of combination of interferon-gamma-inducible protein 10 gene with gemcitabine, a study in murine model.

  Journal of experimental & clinical cancer research : CR 20080101

• Apobec 3F and apobec 3G have no inhibition and hypermutation effect on the human influenza A virus.

  Acta virologica 20080101

• The ubiquitin system, disease, and drug discovery.

  BMC biochemistry 20080101

• The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals.

  BMC molecular biology 20080101

• Ovarian cancer plasticity and epigenomics in the acquisition of a stem-like phenotype.

  Journal of ovarian research 20080101

• Macronuclear genome structure of the ciliate Nyctotherus ovalis: single-gene chromosomes and tiny introns.

  BMC genomics 20080101

• Haploinsufficiency of activation-induced deaminase for antibody diversification and chromosome translocations both in vitro and in vivo.

  PloS one 20080101

• Distinct determinants in HIV-1 Vif and human APOBEC3 proteins are required for the suppression of diverse host anti-viral proteins.

  PloS one 20080101

• Future treatment options for HCV: double, triple, what is the optimal combination?

  Best practice & research. Clinical gastroenterology 20080101

• Molecular analysis of activation-induced cytidine deaminase gene in immunoglobulin-E deficient patients.

  Clinical & developmental immunology 20080101

• Gene expression in Pre-MBT embryos and activation of maternally-inherited program of apoptosis to be executed at around MBT as a fail-safe mechanism in Xenopus early embryogenesis.

  Gene regulation and systems biology 20080101

• Inhibition of DNA methylation is involved in transdifferentiation of myoblasts into smooth muscle cells.

  Molecules and cells 20071231

• Biomimetic aminoacylation of ribonucleotides and RNA with aminoacyl phosphate esters and lanthanum salts.

  Journal of the American Chemical Society 20071226

• Cardiovascular effects of CDP-choline and its metabolites: involvement of peripheral autonomic nervous system.

  European journal of pharmacology 20071222

• Crystal structures of blasticidin S deaminase (BSD): implications for dynamic properties of catalytic zinc.

  The Journal of biological chemistry 20071221

• Production of infectious virus and degradation of APOBEC3G are separable functional properties of human immunodeficiency virus type 1 Vif.

  Virology 20071220

• Recombinant antibodies to an oxidized low-density lipoprotein epitope induce rapid regression of atherosclerosis in apobec-1(-/-)/low-density lipoprotein receptor(-/-) mice.

  Journal of the American College of Cardiology 20071211

• CD45RO enriches for activated, highly mutated human germinal center B cells.

  Blood 20071201

• Oncogenic events triggered by AID, the adverse effect of antibody diversification.

  Carcinogenesis 20071201

• Association of human APOBEC3 cytidine deaminases with the generation of hepatitis virus B x antigen mutants and hepatocellular carcinoma.

  Hepatology (Baltimore, Md.) 20071201

• Transport proteins PotD and Crr of Escherichia coli, novel fusion partners for heterologous protein expression.

  Biochimica et biophysica acta 20071201

• Epigenetic regulation of chemosensitivity to 5-fluorouracil and cisplatin by zebularine in oral squamous cell carcinoma.

  International journal of oncology 20071201

• Effects of point mutations in the cytidine deaminase domains of APOBEC3B on replication and hypermutation of hepatitis B virus in vitro.

  The Journal of general virology 20071201

• Activation-induced cytidine deaminase induces DNA break repair events more frequently in the Ig switch region than other sites in the mammalian genome.

  European journal of immunology 20071201

• Negative effect of DNA hypermethylation on the outcome of intensive chemotherapy in older patients with high-risk myelodysplastic syndromes and acute myeloid leukemia following myelodysplastic syndrome.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20071201

• [Single-nucleotide polymorphisms of the cytidine deaminase gene in childhood with acute leukemia and normal Chinese children].

  Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20071201

• Structural basis of the initial binding of tRNA(Ile) lysidine synthetase TilS with ATP and L-lysine.

  Structure (London, England : 1993) 20071201

• Discordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals.

  PLoS pathogens 20071201

• Rates of spontaneous disintegration of DNA and the rate enhancements produced by DNA glycosylases and deaminases.

  Biochemistry 20071127

• Derepression of microRNA-mediated protein translation inhibition by apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G) and its family members.

  The Journal of biological chemistry 20071116

• Differentiation and Ig-allele switch in cell line WEHI-231.

  Journal of immunology (Baltimore, Md. : 1950) 20071115

• Spontaneous class switch recombination in B cell lymphopoiesis generates aberrant switch junctions and is increased after VDJ rearrangement.

  Journal of immunology (Baltimore, Md. : 1950) 20071115

• Localization and differential expression of activation-induced cytidine deaminase in the amphibian Xenopus upon antigen stimulation and during early development.

  Journal of immunology (Baltimore, Md. : 1950) 20071115

• Transcriptional profiling of antigen-dependent murine B cell differentiation and memory formation.

  Journal of immunology (Baltimore, Md. : 1950) 20071115

• Elevated expression of activation induced cytidine deaminase in peripheral blood mononuclear cells precedes AIDS-NHL diagnosis.

  AIDS (London, England) 20071112

• Conditional intestinal lipotoxicity in Apobec-1-/- Mttp-IKO mice: a survival advantage for mammalian intestinal apolipoprotein B mRNA editing.

  The Journal of biological chemistry 20071109

• Low dose Zebularine treatment enhances immunogenicity of tumor cells.

  Cancer letters 20071108

• Phototriggers for nucleobases with improved photochemical properties.

  Organic letters 20071108

• APOBEC3G inhibits DNA strand transfer during HIV-1 reverse transcription.

  The Journal of biological chemistry 20071102

• Limited antitumor-effect associated with toxicity of the experimental cytotoxic drug cyclopentenyl cytosine in NOD/scid mice with acute lymphoblastic leukemia.

  Leukemia research 20071101

• Mass spectrometry analysis of HIV-1 Vif reveals an increase in ordered structure upon oligomerization in regions necessary for viral infectivity.

  Proteins 20071101

• Cytidine deamination assay to differentiate Staphylococcus aureus from other staphylococci.

  Letters in applied microbiology 20071101

• N-hydroxy-N'-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxy-benzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: synergistic antitumor activity with arabinofuranosylcytosine.

  International journal of oncology 20071101

• High rate of starvation-associated mutagenesis in Ung(-) yeast caused by the overproduction of human activation-induced deaminase.

  Current genetics 20071101

• Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair.

  Journal of immunology (Baltimore, Md. : 1950) 20071101

• S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase.

  Immunity 20071101

• T cell responses to human endogenous retroviruses in HIV-1 infection.

  PLoS pathogens 20071101

• [Prediction of adverse drug reactions based on genomic information].

  Nihon rinsho. Japanese journal of clinical medicine 20071028

• Characterization of a novel Cullin5 binding domain in HIV-1 Vif.

  Journal of molecular biology 20071026

• The interferon-induced expression of APOBEC3G in human blood-brain barrier exerts a potent intrinsic immunity to block HIV-1 entry to central nervous system.

  Virology 20071025

• Solid-phase synthesis of symmetrical 5',5'-dinucleoside mono-, di-, tri-, and tetraphosphodiesters.

  Organic letters 20071025

• Genotype-based methods for anticipating gemcitabine-related severe toxicities may lead to false-negative results.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071020

• Role of activation-induced deaminase protein kinase A phosphorylation sites in Ig gene conversion and somatic hypermutation.

  Journal of immunology (Baltimore, Md. : 1950) 20071015

• Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA.

  Journal of molecular biology 20071005

• Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1.

  Neuron 20071004

• Extensive mutagenesis experiments corroborate a structural model for the DNA deaminase domain of APOBEC3G.

  FEBS letters 20071002

• Effects of apricitabine and other nucleoside reverse transcriptase inhibitors on replication of mitochondrial DNA in HepG2 cells.

  Antiviral research 20071001

• Spectroscopic and molecular modeling studies of the interaction between cytidine and human serum albumin and its analytical application.

  Biopolymers 20071001

• Transmembrane activator and calcium modulator and cyclophilin ligand interactor enhances CD40-driven plasma cell differentiation.

  The Journal of allergy and clinical immunology 20071001

• Cellular localization and functional characterization of the equilibrative nucleoside transporters of antitumor nucleosides.

  Cancer science 20071001

• Activation-induced cytidine deaminase expression in follicular dendritic cell networks and interfollicular large B cells supports functionality of ectopic lymphoid neogenesis in autoimmune sialoadenitis and MALT lymphoma in Sjögren's syndrome.

  Journal of immunology (Baltimore, Md. : 1950) 20071001

• Chromatin structure regulates gene conversion.

  PLoS biology 20071001

• Toxic death case in a patient undergoing gemcitabine-based chemotherapy in relation with cytidine deaminase downregulation.

  Pharmacogenetics and genomics 20071001

• The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP-G.

  Biochimica et biophysica acta 20071001

• Nicotinamide riboside kinase structures reveal new pathways to NAD+.

  PLoS biology 20071001

• Increased APOBEC3G expression is associated with extensive G-to-A hypermutation in viral DNA in rhesus macaque brain during lentiviral infection.

  Journal of neuropathology and experimental neurology 20071001

• Target cell APOBEC3C can induce limited G-to-A mutation in HIV-1.

  PLoS pathogens 20071001

• Role of APOBEC3 in genetic diversity among endogenous murine leukemia viruses.

  PLoS genetics 20071001

• Estimating the relative contribution of dNTP pool imbalance and APOBEC3G/3F editing to HIV evolution in vivo.

  Journal of computational biology : a journal of computational molecular cell biology 20071001

• [Vertebrate immunity: mutator proteins and their evolution].

  Genetika 20071001

• IL-4-induced AID expression and its relevance to IgA class switch recombination.

  Biochemical and biophysical research communications 20070921

• Deletion of the AU-rich RNA binding protein Apobec-1 reduces intestinal tumor burden in Apc(min) mice.

  Cancer research 20070915

• Fast simultaneous determination of 14 nucleosides and nucleobases in cultured Cordyceps using ultra-performance liquid chromatography.

  Talanta 20070915

• Adenosine deaminase 1 and concentrative nucleoside transporters 2 and 3 regulate adenosine on the apical surface of human airway epithelia: implications for inflammatory lung diseases.

  Biochemistry 20070911

• RNA and DNA binding properties of HIV-1 Vif protein: a fluorescence study.

  The Journal of biological chemistry 20070907

• A hypothesis on the identification of the editing enzyme in plant organelles.

  FEBS letters 20070904

• Computational analysis of RNA editing sites in plant mitochondrial genomes reveals similar information content and a sporadic distribution of editing sites.

  Molecular biology and evolution 20070901

• Hepatitis B virus DNA is subject to extensive editing by the human deaminase APOBEC3C.

  Hepatology (Baltimore, Md.) 20070901

• Frequent occurrence of B-cell lymphomas in angioimmunoblastic T-cell lymphoma and proliferation of Epstein-Barr virus-infected cells in early cases.

  British journal of haematology 20070901

• Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition.

  British journal of haematology 20070901

• Investigation of the Lith6 candidate genes APOBEC1 and PPARG in human gallstone disease.

  Liver international : official journal of the International Association for the Study of the Liver 20070901

• 5-Azacytidine induced methyltransferase-DNA adducts block DNA replication in vivo.

  Cancer research 20070901

• T cells contain an RNase-insensitive inhibitor of APOBEC3G deaminase activity.

  PLoS pathogens 20070901

• Activation-induced cytidine deaminase-mediated sequence diversification is transiently targeted to newly integrated DNA substrates.

  The Journal of biological chemistry 20070831

• Strand-biased spreading of mutations during somatic hypermutation.

  Science (New York, N.Y.) 20070831

• Antiproliferative effects of sapacitabine (CYC682), a novel 2'-deoxycytidine-derivative, in human cancer cells.

  British journal of cancer 20070828

• Intrinsic electrophilic properties of nucleosides: photoelectron spectroscopy of their parent anions.

  The Journal of chemical physics 20070828

• Ab initio ONIOM-molecular dynamics (MD) study on the deamination reaction by cytidine deaminase.

  The journal of physical chemistry. B 20070823

• Expression of activation-induced cytidine deaminase in human hepatocytes via NF-kappaB signaling.

  Oncogene 20070816

• Direct detection of ligand binding to Sepharose-immobilised protein using saturation transfer double difference (STDD) NMR spectroscopy.

  Biochemical and biophysical research communications 20070810

• Exogenous nucleic acids and nucleotides are efficiently hydrolysed and taken up as nucleosides by intestinal explants from suckling piglets.

  The British journal of nutrition 20070801

• The intrinsic antiretroviral factor APOBEC3B contains two enzymatically active cytidine deaminase domains.

  Virology 20070801

• Incorporation of two modified nucleosides allows selective platination of an oligonucleotide making it suitable for duplex cross-linking.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070801

• Ultrafast electronic relaxation in guanosine is promoted by hydrogen bonding with cytidine.

  Journal of the American Chemical Society 20070801

• Cyclopentenyl cytosine (CPEC): an overview of its in vitro and in vivo activity.

  Current cancer drug targets 20070801

• Qualitative and quantitative analyses of nucleosides and nucleobases in Ganoderma spp. by HPLC-DAD-MS.

  Journal of pharmaceutical and biomedical analysis 20070727

• Pharmacogenomics of gemcitabine: can genetic studies lead to tailor-made therapy?

  British journal of cancer 20070716

• Target sequence accessibility limits activation-induced cytidine deaminase activity in primary mediastinal B-cell lymphoma.

  Cancer research 20070715

• On the prebiotic synthesis of ribonucleotides: photoanomerisation of cytosine nucleosides and nucleotides revisited.

  Chembiochem : a European journal of chemical biology 20070709

• Synergistic inhibition of pancreatic adenocarcinoma cell growth by trichostatin A and gemcitabine.

  Biochimica et biophysica acta 20070701

• Importance of tRNA interactions with 23S rRNA for peptide bond formation on the ribosome: studies with substrate analogs.

  Biological chemistry 20070701

• Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides.

  Cancer research 20070701

• Class switch recombination and somatic hypermutation in early mouse B cells are mediated by B cell and Toll-like receptors.

  Immunity 20070701

• Prediction of C-to-U RNA editing sites in higher plant mitochondria using only nucleotide sequence features.

  Biochemical and biophysical research communications 20070622

• Stacking effects on local structure in RNA: changes in the structure of tandem GA pairs when flanking GC pairs are replaced by isoG-isoC pairs.

  The journal of physical chemistry. B 20070621

• Cholinergic precursors in the treatment of cognitive impairment of vascular origin: ineffective approaches or need for re-evaluation?

  Journal of the neurological sciences 20070615

• Surface-enhanced Raman spectroscopy of soft-landed polyatomic ions and molecules.

  Analytical chemistry 20070615

• Possible involvement of supraspinal opioid and GABA receptors in CDP-choline-induced antinociception in acute pain models in rats.

  Neuroscience letters 20070613

• Avemar, a nontoxic fermented wheat germ extract, induces apoptosis and inhibits ribonucleotide reductase in human HL-60 promyelocytic leukemia cells.

  Cancer letters 20070608

• DNA deaminases AID and APOBEC3G act processively on single-stranded DNA.

  DNA repair 20070601

• Cleavage of an RNA analog by Zn(II) macrocyclic catalysts appended with a methyl or an acridine group.

  Journal of inorganic biochemistry 20070601

• Mechanism of action of a new antitumor ribonucleoside, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), differs from that of 5-fluorouracil.

  Oncology reports 20070601

• Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr mice.

  Journal of immunology (Baltimore, Md. : 1950) 20070601

• Suppressive effect of culture supernatant of erythrocytes and serum from dogs infected with Babesia gibsoni on the morphological maturation of canine reticulocytes in vitro.

  Journal of veterinary science 20070601

• Exposure to organophosphates reduces the expression of neurotrophic factors in neonatal rat brain regions: similarities and differences in the effects of chlorpyrifos and diazinon on the fibroblast growth factor superfamily.

  Environmental health perspectives 20070601

• DNA methyltransferases as targets for cancer therapy.

  Drugs of today (Barcelona, Spain : 1998) 20070601

• [Single-nucleotide polymorphisms of the cytidine deaminase gene in 53 children with acute leukemia].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20070601

• A review of the role of capecitabine in the treatment of colorectal cancer.

  Therapeutics and clinical risk management 20070601

• A preclinical evaluation of pemetrexed and irinotecan combination as second-line chemotherapy in pancreatic cancer.

  British journal of cancer 20070507

• Electrochemical behaviors of native and thermally denatured fish DNA in the presence of cytosine derivatives and porphyrin by cyclic voltammetry using boron-doped diamond electrode.

  Bioelectrochemistry (Amsterdam, Netherlands) 20070501

• Design, synthesis, and antiviral properties of 4'-substituted ribonucleosides as inhibitors of hepatitis C virus replication: the discovery of R1479.

  Bioorganic & medicinal chemistry letters 20070501

• Magnaporthe grisea infection triggers RNA variation and antisense transcript expression in rice.

  Plant physiology 20070501

• Human equilibrative nucleoside transporter 1 is associated with the chemosensitivity of gemcitabine in human pancreatic adenocarcinoma and biliary tract carcinoma cells.

  Oncology reports 20070501

• Treatment combining X-irradiation and a ribonucleoside anticancer drug, TAS106, effectively suppresses the growth of tumor cells transplanted in mice.

  International journal of radiation oncology, biology, physics 20070501

• Centrosomal latency of incoming foamy viruses in resting cells.

  PLoS pathogens 20070501

• Synthesis of 3'-deoxynucleosides with 2-oxabicyclo[3.1.0]hexane sugar moieties: addition of difluorocarbene to a 3',4'-unsaturated uridine derivative and 1,2-dihydrofurans derived from D- and L-xylose1.

  The Journal of organic chemistry 20070427

• A nearly isosteric photosensitive amide-backbone substitution allows enzyme activity switching in ribonuclease s.

  Journal of the American Chemical Society 20070425

• Virion-associated uracil DNA glycosylase-2 and apurinic/apyrimidinic endonuclease are involved in the degradation of APOBEC3G-edited nascent HIV-1 DNA.

  The Journal of biological chemistry 20070420

• Expression, purification, characterization, and in vivo targeting of trypanosome CTP synthetase for treatment of African sleeping sickness.

  The Journal of biological chemistry 20070420

• Overexpression of activation-induced cytidine deaminase in B cells is associated with production of highly pathogenic autoantibodies.

  Journal of immunology (Baltimore, Md. : 1950) 20070415

• Stoichiometry of the antiviral protein APOBEC3G in HIV-1 virions.

  Virology 20070410

• Selective inhibition of Alu retrotransposition by APOBEC3G.

  Gene 20070401

• Known components of the immunoglobulin A:T mutational machinery are intact in Burkitt lymphoma cell lines with G:C bias.

  Molecular immunology 20070401

• Thermodynamic properties of enzyme-catalyzed reactions involving cytosine, uracil, thymine, and their nucleosides and nucleotides.

  Biophysical chemistry 20070401

• Kinetic analysis of oligo(C) formation from the 5'-monophosphorimidazolide of cytidine with Pb(II) ion catalyst at 10-75 degrees C.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20070401

• Identification of amino acid residues in APOBEC3G required for regulation by human immunodeficiency virus type 1 Vif and Virion encapsidation.

  Journal of virology 20070401

• Cytotoxic activity of gemcitabine and correlation with expression profile of drug-related genes in human lymphoid cells.

  Pharmacological research 20070401

• Apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G: a possible role in the resistance to HIV of HIV-exposed seronegative individuals.

  The Journal of infectious diseases 20070401

• Arsenic trioxide induces p53-dependent apoptotic signals in myeloma cells with SiRNA-silenced p53: MAP kinase pathway is preferentially activated in cells expressing inactivated p53.

  International journal of oncology 20070401

• DNA-dependent protein kinase inhibits AID-induced antibody gene conversion.

  PLoS biology 20070401

• Analysis of 6912 unselected somatic hypermutations in human VDJ rearrangements reveals lack of strand specificity and correlation between phase II substitution rates and distance to the nearest 3' activation-induced cytidine deaminase target.

  Journal of immunology (Baltimore, Md. : 1950) 20070401

• Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium.

  Nature medicine 20070401

• Progesterone regulation of implantation-related genes: new insights into the role of oestrogen.

  Cellular and molecular life sciences : CMLS 20070401

• Providing AID to p53 mutagenesis.

  Nature medicine 20070401

• Cell-specific regulation of APOBEC3F by interferons.

  Acta biochimica et biophysica Sinica 20070401

• Population stratification of a common APOBEC gene deletion polymorphism.

  PLoS genetics 20070401

• HyperPack: a software package for the study of levels, contexts, and patterns of APOBEC-mediated hypermutation in HIV.

  AIDS research and human retroviruses 20070401

• Electron-transfer induced repair of 6-4 photoproducts in DNA: a computational study.

  The journal of physical chemistry. A 20070329

• A novel human B cell subpopulation representing the initial germinal center population to express AID.

  Blood 20070315

• T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells.

  Journal of immunology (Baltimore, Md. : 1950) 20070315

• Recombination in feline lentiviral genomes during experimental cross-species infection.

  Virology 20070301

• Analysis of Vif-induced APOBEC3G degradation using an alpha-complementation assay.

  Virology 20070301

• 2'-C-methylcytidine as a potent and selective inhibitor of the replication of foot-and-mouth disease virus.

  Antiviral research 20070301

• DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes.

  Molecular pharmacology 20070301

• Aging murine B cells have decreased class switch induced by anti-CD40 or BAFF.

  Experimental gerontology 20070301

• Antiviral protein APOBEC3G localizes to ribonucleoprotein complexes found in P bodies and stress granules.

  Journal of virology 20070301

• Expression and secretion of immunoglobulin alpha heavy chain with diverse VDJ recombinations by human epithelial cancer cells.

  Molecular immunology 20070301

• Functional characterization of APOBEC-1 complementation factor phosphorylation sites.

  Biochimica et biophysica acta 20070301

• The fluorouridine insensitive 1 (fur1) mutant is defective in equilibrative nucleoside transporter 3 (ENT3), and thus represents an important pyrimidine nucleoside uptake system in Arabidopsis thaliana.

  The Plant journal : for cell and molecular biology 20070301

• Post-transcriptional modifications in the small subunit ribosomal RNA from Thermotoga maritima, including presence of a novel modified cytidine.

  RNA (New York, N.Y.) 20070301

• APOBEC-mediated viral restriction: not simply editing?

  Trends in biochemical sciences 20070301

• Specific targeted antiviral therapy for hepatitis C.

  Current gastroenterology reports 20070301

• A possible role of thymidine phosphorylase expression and 5-fluorouracil increased sensitivity in oropharyngeal cancer patients.

  Journal of cellular and molecular medicine 20070301

• HPLC retention behavior on hydride-based stationary phases.

  Journal of separation science 20070301

• APOBEC3 inhibits mouse mammary tumour virus replication in vivo.

  Nature 20070222

• LC-MS/MS method for simultaneous determination of viramidine and ribavirin levels in monkey red blood cells.

  Journal of pharmaceutical and biomedical analysis 20070219

• Synthesis of 2'-C-alpha-(hydroxyalkyl) and 2'-C-alpha-alkylcytidine phosphoramidites: analogues for probing solvent interactions with RNA.

  The Journal of organic chemistry 20070216

• AID-/-mus-/- mice are agammaglobulinemic and fail to maintain B220-CD138+ plasma cells.

  Journal of immunology (Baltimore, Md. : 1950) 20070215

• Response to correspondence: Pardossi-Piquard et al., 'Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betAAPP and APLP.' Neuron 46, 541-554.

  Neuron 20070215

• Specific mutations in transmembrane helix 8 of human concentrative Na+/nucleoside cotransporter hCNT1 affect permeant selectivity and cation coupling.

  Biochemistry 20070213

• Distinct patterns of cytokine regulation of APOBEC3G expression and activity in primary lymphocytes, macrophages, and dendritic cells.

  The Journal of biological chemistry 20070209

• The nuclear DNA deaminase AID functions distributively whereas cytoplasmic APOBEC3G has a processive mode of action.

  DNA repair 20070204

• Activation-induced cytidine deaminase acts on double-strand breaks in vitro.

  Molecular immunology 20070201

• Infection of human B cells with Epstein-Barr virus results in the expression of somatic hypermutation-inducing molecules and in the accrual of oncogene mutations.

  Molecular immunology 20070201

• Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis.

  International journal of cancer 20070201

• Genetic association of interleukin-1beta (-511C/T) and interleukin-1 receptor antagonist (86 bp repeat) polymorphisms with Type 2 diabetes mellitus in North Indians.

  Clinica chimica acta; international journal of clinical chemistry 20070201

• Characterization of resistance to cytosine arabinoside (Ara-C) in NALM-6 human B leukemia cells.

  Clinica chimica acta; international journal of clinical chemistry 20070201

• Purine and pyrimidine nucleosides preserve human astrocytoma cell adenylate energy charge under ischemic conditions.

  Neurochemistry international 20070201

• Stimulation of cell surface CCR5 and CD40 molecules by their ligands or by HSP70 up-regulates APOBEC3G expression in CD4(+) T cells and dendritic cells.

  Journal of immunology (Baltimore, Md. : 1950) 20070201

• Dual effect of APOBEC3G on Hepatitis B virus.

  The Journal of general virology 20070201

• Zebularine inhibits human acute myeloid leukemia cell growth in vitro in association with p15INK4B demethylation and reexpression.

  Experimental hematology 20070201

• Nitrogenous ovipositional deterrents in the leaves of sweet pepper (Capsicum annuum) at the mature stage against the leafminer, Liriomyza trifolii (Burgess).

  Bioscience, biotechnology, and biochemistry 20070201

• Newly synthesized APOBEC3G is incorporated into HIV virions, inhibited by HIV RNA, and subsequently activated by RNase H.

  PLoS pathogens 20070201

• [DNA methylation and cancer].

  Gan to kagaku ryoho. Cancer & chemotherapy 20070201

• Generation and characterization of APOBEC3G-positive 293T cells for HIV-1 Vif study.

  The journal of medical investigation : JMI 20070201

• Cloning and characterization of an alternative splicing transcript of the gene coding for human cytidine deaminase.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20070201

• APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G.

  The Journal of biological chemistry 20070126

• The APOBEC-2 crystal structure and functional implications for the deaminase AID.

  Nature 20070125

• Somatic hypermutation: activation-induced deaminase for C/G followed by polymerase eta for A/T.

  The Journal of experimental medicine 20070122

• Photophysical characterization of a cytidine-guanosine tethered phthalocyanine-fullerene dyad.

  Chemical communications (Cambridge, England) 20070121

• Biochemical differentiation of APOBEC3F and APOBEC3G proteins associated with HIV-1 life cycle.

  The Journal of biological chemistry 20070119

• Antibody class switching mediated by yeast endonuclease-generated DNA breaks.

  Science (New York, N.Y.) 20070119

• Immunology. Antibodies get a break.

  Science (New York, N.Y.) 20070119

• Requirement of non-canonical activity of uracil DNA glycosylase for class switch recombination.

  The Journal of biological chemistry 20070105

• AID mutates a non-immunoglobulin transgene independent of chromosomal position.

  Molecular immunology 20070101

• Somatic mutations and activation-induced cytidine deaminase (AID) expression in established rheumatoid factor-producing lymphoblastoid cell line.

  Molecular immunology 20070101

• HIV-1 Vif protein blocks the cytidine deaminase activity of B-cell specific AID in E. coli by a similar mechanism of action.

  Molecular immunology 20070101

• Monocyte fructose 1,6-bisphosphatase and cytidine deaminase enzyme activities: potential pharmacodynamic measures of calcitriol effects in cancer patients.

  Cancer chemotherapy and pharmacology 20070101

• Regulation of epsilon germline transcription and switch region mutations by IgH locus 3' enhancers in transgenic mice.

  Blood 20070101

• APOBEC3G expression is restricted to epithelial cells of the proximal convoluted tubules and is not expressed in the glomeruli of macaques.

  The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20070101

• The phosphofructokinase-B (MJ0406) from Methanocaldococcus jannaschii represents a nucleoside kinase with a broad substrate specificity.

  Extremophiles : life under extreme conditions 20070101

• Conformational analysis of the telomerase RNA pseudoknot hairpin by Raman spectroscopy.

  RNA (New York, N.Y.) 20070101

• Human T cell leukemia virus type I is resistant to the antiviral effects of APOBEC3.

  Journal of virological methods 20070101

• Zinc chelation inhibits HIV Vif activity and liberates antiviral function of the cytidine deaminase APOBEC3G.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070101

• Collision-induced dissociation of cytidine and its derivatives.

  Journal of mass spectrometry : JMS 20070101

• Enhanced intra-switch region recombination during immunoglobulin class switch recombination in 53BP1-/- B cells.

  European journal of immunology 20070101

• Apoptosis, proliferation and differentiation patterns are influenced by Zebularine and SAHA in pancreatic cancer models.

  Scandinavian journal of gastroenterology 20070101

• Pharmacokinetics of gemcitabine in Japanese cancer patients: the impact of a cytidine deaminase polymorphism.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070101

• Insights into DNA deaminases.

  Nature structural & molecular biology 20070101

• Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma.

  The Journal of allergy and clinical immunology 20070101

• Expression of APOBEC3G in kidney cells.

  Tissue antigens 20070101

• Zebularine reactivates silenced E-cadherin but unlike 5-Azacytidine does not induce switching from latent to lytic Epstein-Barr virus infection in Burkitt's lymphoma Akata cells.

  Molecular cancer 20070101

• Antisense oligonucleotide-induced alternative splicing of the APOB mRNA generates a novel isoform of APOB.

  BMC molecular biology 20070101

• Construction and characterization of new piggyBac vectors for constitutive or inducible expression of heterologous gene pairs and the identification of a previously unrecognized activator sequence in piggyBac.

  BMC biotechnology 20070101

• FRA-1 protein overexpression is a feature of hyperplastic and neoplastic breast disorders.

  BMC cancer 20070101

• Polymorphisms of CUL5 are associated with CD4+ T cell loss in HIV-1 infected individuals.

  PLoS genetics 20070101

• Reconstitution of an infectious human endogenous retrovirus.

  PLoS pathogens 20070101

• Effect of gonococcal lipooligosaccharide variation on human monocytic cytokine profile.

  BMC microbiology 20070101

• New pandemics: HIV and AIDS, HCV and chronic hepatitis, influenza virus and flu.

  Retrovirology 20070101

• Heteroplasmic mutation of mitochondrial DNA D-loop and 4977-bp deletion in human cancer cells during mitochondrial DNA depletion.

  Mitochondrion 20070101

• Molecular mechanisms of antibody somatic hypermutation.

  Annual review of biochemistry 20070101

• Regulation of AID function in vivo.

  Advances in experimental medicine and biology 20070101

• Targeting of AID to immunoglobulin genes.

  Advances in experimental medicine and biology 20070101

• Targeting AID to the Ig genes.

  Advances in experimental medicine and biology 20070101

• Regulation of activation induced deaminase via phosphorylation.

  Advances in experimental medicine and biology 20070101

• Developmental stage related patterns of codon usage and genomic GC content: searching for evolutionary fingerprints with models of stem cell differentiation.

  Genome biology 20070101

• Antitumor activity and pharmacokinetics of liposomes containing lipophilic gemcitabine prodrugs.

  Anticancer research 20070101

• Regulation of metabolic networks by small molecule metabolites.

  BMC bioinformatics 20070101

• Replicative homeostasis III: implications for antiviral therapy and mechanisms of response and non-response.

  Virology journal 20070101

• APOBEC3G levels predict rates of progression to AIDS.

  Retrovirology 20070101

• C-type natriuretic peptide regulates endochondral bone growth through p38 MAP kinase-dependent and -independent pathways.

  BMC developmental biology 20070101

• Model structure of human APOBEC3G.

  PloS one 20070101

• A recurrent stop-codon mutation in succinate dehydrogenase subunit B gene in normal peripheral blood and childhood T-cell acute leukemia.

  PloS one 20070101

• Thermolabile methylenetetrahydrofolate reductase C677T polymorphism and homocysteine are risk factors for coronary artery disease in Moroccan population.

  Journal of biomedicine & biotechnology 20070101

• Quantitative determination of the cytidine deaminase inhibitor tetrahydrouridine (THU) in mouse plasma by liquid chromatography/electrospray ionization tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20070101

• Detection of cancer clones in human colorectal adenoma as revealed by increased DNA instability and other bio-markers.

  European journal of histochemistry : EJH 20070101

• HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system.

  Virology journal 20070101

• Discovery of activation-induced cytidine deaminase, the engraver of antibody memory.

  Advances in immunology 20070101

• DNA deamination in immunity: AID in the context of its APOBEC relatives.

  Advances in immunology 20070101

• The role of activation-induced deaminase in antibody diversification and chromosome translocations.

  Advances in immunology 20070101

• Targeting of AID-mediated sequence diversification by cis-acting determinants.

  Advances in immunology 20070101

• AID-initiated purposeful mutations in immunoglobulin genes.

  Advances in immunology 20070101

• Evolution of the immunoglobulin heavy chain class switch recombination mechanism.

  Advances in immunology 20070101

• Beyond SHM and CSR: AID and related cytidine deaminases in the host response to viral infection.

  Advances in immunology 20070101

• Role of AID in tumorigenesis.

  Advances in immunology 20070101

• Pathophysiology of B-cell intrinsic immunoglobulin class switch recombination deficiencies.

  Advances in immunology 20070101

• Immunoglobulin somatic hypermutation.

  Annual review of genetics 20070101

• DNA-uracil and human pathology.

  Molecular aspects of medicine 20070101

• Synergistic activity of troxacitabine (Troxatyl) and gemcitabine in pancreatic cancer.

  BMC cancer 20070101

• Association of VEGF-1499C-->T polymorphism with diabetic nephropathy in type 1 diabetes mellitus.

  Journal of diabetes and its complications 20070101

• Biochemical characterization of a recombinant Japanese encephalitis virus RNA-dependent RNA polymerase.

  BMC molecular biology 20070101

• Analysis of the contribution of cellular and viral RNA to the packaging of APOBEC3G into HIV-1 virions.

  Retrovirology 20070101

• Nucleoside and nucleotide reverse transcriptase inhibitors in children.

  Clinical drug investigation 20070101

• Mass spectrometric identification of Rab23 phosphorylation as a response to challenge by cytidine 3',5'-cyclic monophosphate in mouse brain.

  Rapid communications in mass spectrometry : RCM 20070101

• Host factors influencing susceptibility to HIV infection and AIDS progression.

  Retrovirology 20070101

• Evolution of RNA editing sites in the mitochondrial small subunit rRNA of the Myxomycota.

  Methods in enzymology 20070101

• Measuring editing activity and identifying cytidine-to-uridine mRNA editing factors in cells and biochemical isolates.

  Methods in enzymology 20070101

• Mouse models as tools to explore cytidine-to-uridine RNA editing.

  Methods in enzymology 20070101

• Characterization of the de novo biosynthetic enzyme of platelet activating factor, DDT-insensitive cholinephosphotransferase, of human mesangial cells.

  Mediators of inflammation 20070101

• Targeting APOBEC3A to the viral nucleoprotein complex confers antiviral activity.

  Retrovirology 20070101

• The restriction of zoonotic PERV transmission by human APOBEC3G.

  PloS one 20070101

• [Subcellular localization of APOBEC3G by confocal laser scanning microscope (CLSM)].

  Bing du xue bao = Chinese journal of virology 20070101

• Immunodeficiencies due to defects of class-switch recombination.

  Immunologic research 20070101

• Intraperitoneal administration of CDP-choline and its cholinergic and pyrimidinergic metabolites induce hyperglycemia in rats: involvement of the sympathoadrenal system.

  Archives of physiology and biochemistry 20070101

• DMS footprinting of structured RNAs and RNA-protein complexes.

  Nature protocols 20070101

• The structure of Mycobacteria 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase, an essential enzyme, provides a platform for drug discovery.

  BMC structural biology 20070101

• Control of gag-pol gene expression in the Candida albicans retrotransposon Tca2.

  BMC molecular biology 20070101

• Development of novel thioguanosine analogs with the ability to specifically modify cytidine.

  Nucleic acids symposium series (2004) 20070101

• Synthesis of 4'-selenoribonucleosides.

  Nucleic acids symposium series (2004) 20070101

• Enzymatic incorporation of 2-amino-6-vinylpurine derivative.

  Nucleic acids symposium series (2004) 20070101

• A novel apoptotic pathway of 3'-Ethynylcytidine(ECyd) involving the inhibition of RNA synthesis--the possibility of RNase L activated pathway as a target of ECyd.

  Nucleic acids symposium series (2004) 20070101

• Global DNA hypomethylation in liver cancer cases and controls: a phase I preclinical biomarker development study.

  Epigenetics 20070101

• The dimerization domain of HIV-1 viral infectivity factor Vif is required to block virion incorporation of APOBEC3G.

  Retrovirology 20070101

• Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling.

  BMC biochemistry 20070101

• Studies on thermal stability of human cytidine deaminase.

  Nucleosides, nucleotides & nucleic acids 20070101

• Synthesis of pyrene labeled RNA for fluorescence measurements.

  Nucleosides, nucleotides & nucleic acids 20070101

• Homogeneous fluorescence assays for RNA diagnosis by pyrene-conjugated 2'-O-methyloligoribonucleotides.

  Nucleosides, nucleotides & nucleic acids 20070101

• Choke point analysis of metabolic pathways in E.histolytica: a computational approach for drug target identification.

  Bioinformation 20070101

• Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination.

  Critical reviews in immunology 20070101

• Characterization of copper(II) interactions with sinefungin, a nucleoside antibiotic: combined potentiometric, spectroscopic and DFT studies.

  Bioinorganic chemistry and applications 20070101

• Activation-induced cytidine deaminase expression in gastric cancer.

  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20070101

• Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer.

  British journal of cancer 20061218

• Nanostructures of APOBEC3G support a hierarchical assembly model of high molecular mass ribonucleoprotein particles from dimeric subunits.

  The Journal of biological chemistry 20061215

• Pharmacokinetics, metabolism, and oral bioavailability of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine in mice.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20061215

• N-terminal and C-terminal cytosine deaminase domain of APOBEC3G inhibit hepatitis B virus replication.

  World journal of gastroenterology 20061214

• Epstein-Barr virus nuclear antigen 2 inhibits AID expression during EBV-driven B-cell growth.

  Blood 20061201

• Activation-induced cytidine deaminase: structure-function relationship as based on the study of mutants.

  Human mutation 20061201

• Reversed functional organization of mouse and human APOBEC3 cytidine deaminase domains.

  The Journal of biological chemistry 20061201

• Gut IgA class switch recombination in the absence of CD40 does not occur in the lamina propria and is independent of germinal centers.

  Journal of immunology (Baltimore, Md. : 1950) 20061201

• Template properties of mutagenic cytosine analogues in reverse transcription.

  Nucleic acids research 20061201

• Transcriptional regulation by competing transcription factor modules.

  PLoS computational biology 20061201

• Cellular interactions of virion infectivity factor (Vif) as potential therapeutic targets: APOBEC3G and more?

  Current drug targets 20061201

• mRNA expression and RNA editing (2451 C-to-U) of IL-12 receptor beta2 in adult atopic patients.

  Journal of Korean medical science 20061201

• The fittest versus the flattest: experimental confirmation of the quasispecies effect with subviral pathogens.

  PLoS pathogens 20061201

• Determination of the impurity profile of adenosine by means of ion-pair reversed-phase chromatography.

  Pharmeuropa scientific notes 20061201

• Azacytidine (Vidaza(R)) in the treatment of myelodysplastic syndromes.

  Therapeutics and clinical risk management 20061201

• Numerical characterization of DNA sequences based on the k-step Markov chain transition probability.

  Journal of computational chemistry 20061130

• The acidic domain of hnRNPQ (NSAP1) has structural similarity to Barstar and binds to Apobec1.

  Biochemical and biophysical research communications 20061117

• Epigenetic regulation of tumor endothelial cell anergy: silencing of intercellular adhesion molecule-1 by histone modifications.

  Cancer research 20061115

• APOBEC-1 and AID are nucleo-cytoplasmic trafficking proteins but APOBEC3G cannot traffic.

  Biochemical and biophysical research communications 20061110

• Addition of difluorocarbene to 4',5'-unsaturated nucleosides: synthesis and deoxygenation reactions of difluorospirocyclopropane nucleosides.

  The Journal of organic chemistry 20061110

• Computational analyses show A-to-G mutations correlate with nascent mRNA hairpins at somatic hypermutation hotspots.

  DNA repair 20061108

• Characterization and quantification of eight water-soluble constituents in tubers of Pinellia ternata and in tea granules from the Chinese multiherb remedy Xiaochaihu-tang.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061107

• Sequence-specific interactions in the RNA-binding domain of Escherichia coli transcription termination factor Rho.

  The Journal of biological chemistry 20061103

• Synthesis and pharmacokinetics of valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine.

  Journal of medicinal chemistry 20061102

• Additional food folate derived exclusively from natural sources improves folate status in young women with the MTHFR 677 CC or TT genotype.

  The Journal of nutritional biochemistry 20061101

• Gene transfer of cytidine deaminase protects myelopoiesis from cytidine analogs in an in vivo murine transplant model.

  Blood 20061101

• HIV accomplices and adversaries in macrophage infection.

  Journal of leukocyte biology 20061101

• Enthalpy of the B-to-Z conformational transition of a DNA oligonucleotide determined by isothermal titration calorimetry.

  Biophysical journal 20061101

• High expression of APOBEC3G in patients infected with hepatitis C virus.

  Journal of molecular histology 20061101

• Natural resistance to HIV infection: The Vif-APOBEC interaction.

  Comptes rendus biologies 20061101

• A role for PCNA ubiquitination in immunoglobulin hypermutation.

  PLoS biology 20061101

• Novel in vitro screening system for monoclonal antibodies using hypermutating chicken B cell library.

  Journal of bioscience and bioengineering 20061101

• The antinociceptive effects of centrally administered CDP-choline on acute pain models in rats: the involvement of cholinergic system.

  Brain research 20061030

• Forced expression of AID facilitates the isolation of class switch variants from hybridoma cells.

  Journal of immunological methods 20061020

• Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases.

  Journal of medicinal chemistry 20061019

• Base and phosphate electron detachment energies of deoxyribonucleotide anions.

  Journal of the American Chemical Society 20061018

• Somatic hypermutation and class switch recombination in Msh6(-/-)Ung(-/-) double-knockout mice.

  Journal of immunology (Baltimore, Md. : 1950) 20061015

• Antiallergic drugs, azelastine hydrochloride and epinastine hydrochloride, inhibit ongoing IgE secretion of rat IgE-producing hybridoma FE-3 cells.

  European journal of pharmacology 20061010

• APOBEC3G genetic variants and their association with risk of HIV infection in highly exposed Caucasians.

  AIDS (London, England) 20061003

• Differential expression patterns of recombination-activating genes in individual mature B cells in juvenile idiopathic arthritis.

  Annals of the rheumatic diseases 20061001

• Trypanosoma brucei: a survey of pyrimidine transport activities.

  Experimental parasitology 20061001

• An accurate fluorescent assay for quantifying the extent of RNA editing.

  RNA (New York, N.Y.) 20061001

• STAT1-independent cell type-specific regulation of antiviral APOBEC3G by IFN-alpha.

  Journal of immunology (Baltimore, Md. : 1950) 20061001

• Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signaling.

  Immunity 20061001

• Boronate functionalised polymer monoliths for microscale affinity chromatography.

  The Analyst 20061001

• A mass balance and disposition study of the DNA methyltransferase inhibitor zebularine (NSC 309132) and three of its metabolites in mice.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20061001

• [Inhibition of hepatitis B and duck hepatitis B virus replication by APOBEC3G].

  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20061001

• Interaction between HIV-1 and APOBEC3 sub-family of proteins.

  Current HIV research 20061001

• DNA repair in HIV-1 infection: a case for inhibitors of cellular co-factors?

  Current HIV research 20061001

• The anti-HIV-1 editing enzyme APOBEC3G binds HIV-1 RNA and messenger RNAs that shuttle between polysomes and stress granules.

  The Journal of biological chemistry 20060929

• Dysregulated TCL1 requires the germinal center and genome instability for mature B-cell transformation.

  Blood 20060915

• Flexibility and adaptability in binding of E. coli cytidine repressor to different operators suggests a role in differential gene regulation.

  Journal of molecular biology 20060915

• AID and Igh switch region-Myc chromosomal translocations.

  DNA repair 20060908

• The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice.

  The Journal of experimental medicine 20060904

• Human cytidine deaminase: a three-dimensional homology model of a tetrameric metallo-enzyme inferred from the crystal structure of a distantly related dimeric homologue.

  Journal of molecular graphics & modelling 20060901

• Uridine and cytidine in the brain: their transport and utilization.

  Brain research reviews 20060901

• Activation-induced cytidine deaminase (AID) is expressed in normal spermatogenesis but only infrequently in testicular germ cell tumours.

  The Journal of pathology 20060901

• PI3-kinase activity modulates apo B available for hepatic VLDL production in apobec-1-/- mice.

  American journal of physiology. Gastrointestinal and liver physiology 20060901

• Reversal of p53 epigenetic silencing in multiple myeloma permits apoptosis by a p53 activator.

  Cancer biology & therapy 20060901

• Activation-induced deaminase: light and dark sides.

  Trends in molecular medicine 20060901

• Pathogenesis of AIDS lymphoma: role of oncogenic viruses and B cell activation-associated molecular lesions.

  Current opinion in oncology 20060901

• Induction of IgE and allergic-type responses in fur mite-infested mice.

  European journal of immunology 20060901

• Antiviral potency of APOBEC proteins does not correlate with cytidine deamination.

  Journal of virology 20060901

• Pax5--a critical inhibitor of plasma cell fate.

  Scandinavian journal of immunology 20060901

• Structure of Methanocaldococcus jannaschii nucleoside kinase: an archaeal member of the ribokinase family.

  Acta crystallographica. Section D, Biological crystallography 20060901

• Association between farm exposure and atopy, according to the CD14 C-159T polymorphism.

  The Journal of allergy and clinical immunology 20060901

• Inhibitors of brain phospholipase A2 activity: their neuropharmacological effects and therapeutic importance for the treatment of neurologic disorders.

  Pharmacological reviews 20060901

• Reactivation of p53 function with a demethylating agent.

  Cancer biology & therapy 20060901

• Citicoline: pharmacological and clinical review, 2006 update.

  Methods and findings in experimental and clinical pharmacology 20060901

• Citicoline (Cognizin) in the treatment of cognitive impairment.

  Clinical interventions in aging 20060901

• Cytidine is a novel substrate for wild-type concentrative nucleoside transporter 2.

  Biochemical and biophysical research communications 20060825

• Syntheses, pi-stacking interactions and base-pairings of uracil pyridinium salts and uracilyl betaines with nucleobases.

  Organic & biomolecular chemistry 20060821

• Comparison of ribonucleic acid homopolymer ionization energies and charge injection barriers.

  The journal of physical chemistry. B 20060817

• Murine retrovirus escapes from murine APOBEC3 via two distinct novel mechanisms.

  Current biology : CB 20060808

• In vitro synergistic cytotoxicity of gemcitabine and pemetrexed and pharmacogenetic evaluation of response to gemcitabine in bladder cancer patients.

  British journal of cancer 20060807

• APOBEC3 proteins inhibit human LINE-1 retrotransposition.

  The Journal of biological chemistry 20060804

• Reply to correspondence by Abreu-Silva et al. regarding Ballana et al.: Mutation T1291C in the mitochondrial 12S rRNA gene involved in deafness in a Cuban family belongs to the macrohaplogroup L1 of African origin.

  Biochemical and biophysical research communications 20060804

• Solventless protocol for efficient bis-N-boc protection of adenosine, cytidine, and guanosine derivatives.

  The Journal of organic chemistry 20060804

• Synthesis, oxidation behavior, crystallization and structure of 2'-methylseleno guanosine containing RNAs.

  Journal of the American Chemical Society 20060802

• Mutational dynamics in human tumors confirm the neutral intrinsic instability of the mitochondrial D-loop poly-cytidine repeat.

  Genes, chromosomes & cancer 20060801

• In vitro selected Con1 subgenomic replicons resistant to 2'-C-methyl-cytidine or to R1479 show lack of cross resistance.

  Virology 20060801

• Tissue-specific sensitivity to AID expression in transgenic mouse models.

  Gene 20060801

• Targeting of somatic hypermutation.

  Nature reviews. Immunology 20060801

• Structure of Staphylococcus aureus cytidine monophosphate kinase in complex with cytidine 5'-monophosphate.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060801

• Interleukin-5 regulates genes involved in B-cell terminal maturation.

  Immunology 20060801

• Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation.

  Immunity 20060801

• [HIV-1 and ubiquitination].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20060801

• [AID controls immunoglobulin class switch recombination].

  Seikagaku. The Journal of Japanese Biochemical Society 20060801

• Inhibition of hepatitis B virus replication by APOBEC3G in vitro and in vivo.

  World journal of gastroenterology 20060728

• Application of a solid-phase beta-triphosphitylating reagent in the synthesis of nucleoside beta-triphosphates.

  The Journal of organic chemistry 20060721

• Vif-deficient HIV reverse transcription complexes (RTCs) are subject to structural changes and mutation of RTC-associated reverse transcription products.

  Virology 20060720

• Identification of a specific domain required for dimerization of activation-induced cytidine deaminase.

  The Journal of biological chemistry 20060714

• Chemical carcinogens in non-enzymatic cytosine deamination: 3-isocyanatoacrylonitrile.

  Journal of molecular modeling 20060701

• A phase I clinical and pharmacokinetic study of CS-682 administered orally in advanced malignant solid tumors.

  Investigational new drugs 20060701

• The role of human nucleoside transporters in cellular uptake of 4'-thio-beta-D-arabinofuranosylcytosine and beta-D-arabinosylcytosine.

  Molecular pharmacology 20060701

• Association of a polymorphism in the betacellulin gene with type 1 diabetes mellitus in two populations.

  Journal of molecular medicine (Berlin, Germany) 20060701

• Gene conversion in human rearranged immunoglobulin genes.

  Immunogenetics 20060701

• The role of the interleukin-10 subfamily members in immunoglobulin production by human B cells.

  Scandinavian journal of immunology 20060701

• Structural phylogenetic analysis of activation-induced deaminase function.

  Journal of immunology (Baltimore, Md. : 1950) 20060701

• E2A expression stimulates Ig hypermutation.

  Journal of immunology (Baltimore, Md. : 1950) 20060701

• Mass spectrometric identification and characterization of antimony complexes with ribose-containing biomolecules and an RNA oligomer.

  Analytical and bioanalytical chemistry 20060701

• Compatibility in the Biomphalaria glabrata/Echinostoma caproni model: Potential involvement of proteins from hemocytes revealed by a proteomic approach.

  Acta tropica 20060701

• Antigen receptors and somatic hypermutation in B-cell chronic lymphocytic leukemia with Richter's transformation.

  Haematologica 20060701

• p53 expression after treatment with zebularine is not due to demethylation.

  Cancer research 20060701

• Reversal of HIV drug resistance and novel strategies to curb HIV infection: the viral infectivity factor Vif as a target and tool of therapy.

  Current drug targets 20060701

• Dissecting non-canonical interactions in frameshift-stimulating mRNA pseudoknots.

  Journal of biomolecular NMR 20060701

• The 1.48 A resolution crystal structure of the homotetrameric cytidine deaminase from mouse.

  Biochemistry 20060627

• First AID (activation-induced cytidine deaminase) is needed to produce high affinity isotype-switched antibodies.

  The Journal of biological chemistry 20060623

• APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism.

  The Journal of biological chemistry 20060623

• Phase I/II trial of doxorubicin and fixed dose-rate infusion gemcitabine in advanced soft tissue sarcomas: a GEIS study.

  British journal of cancer 20060619

• Primary cutaneous follicle center lymphoma and primary cutaneous large B-cell lymphoma, leg type, are both targeted by aberrant somatic hypermutation but demonstrate differential expression of AID.

  Blood 20060615

• A role for Mlh3 in somatic hypermutation.

  DNA repair 20060610

• Assembly of HIV-1 Vif-Cul5 E3 ubiquitin ligase through a novel zinc-binding domain-stabilized hydrophobic interface in Vif.

  Virology 20060605

• Modified nucleosides: an accurate tumour marker for clinical diagnosis of cancer, early detection and therapy control.

  British journal of cancer 20060605

• Long intracellular retention of 4'-thio-arabinofuranosylcytosine 5'-triphosphate as a critical factor for the anti-solid tumor activity of 4'-thio-arabinofuranosylcytosine.

  Cancer chemotherapy and pharmacology 20060601

• Richter's and prolymphocytic transformation of chronic lymphocytic leukemia are associated with high mRNA expression of activation-induced cytidine deaminase and aberrant somatic hypermutation.

  Leukemia 20060601

• Reaction of cytidine nucleotides with cyanoacetylene: support for the intermediacy of nucleoside-2',3'-cyclic phosphates in the prebiotic synthesis of RNA.

  Chembiochem : a European journal of chemical biology 20060601

• Characterization of BlsM, a nucleotide hydrolase involved in cytosine production for the biosynthesis of blasticidin S.

  Chembiochem : a European journal of chemical biology 20060601

• Multifaceted antiviral actions of APOBEC3 cytidine deaminases.

  Trends in immunology 20060601

• Interferon-inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication.

  Hepatology (Baltimore, Md.) 20060601

• Class switch recombination in selective IgA-deficient subjects.

  Clinical and experimental immunology 20060601

• AID for innate immunity to retroviral transformation.

  Immunity 20060601

• A role for activation-induced cytidine deaminase in the host response against a transforming retrovirus.

  Immunity 20060601

• APOBEC3G expression is restricted to neurons in the brains of pigtailed macaques.

  AIDS research and human retroviruses 20060601

• Improved circadian sleep-wake cycle in infants fed a day/night dissociated formula milk.

  Neuro endocrinology letters 20060601

• [Host factors that regulate the intercellular dynamics of HIV-1 genome during the early phase of infection].

  Uirusu 20060601

• Comparative analysis of the antiretroviral activity of APOBEC3G and APOBEC3F from primates.

  Virology 20060525

• Structural and kinetic characterization of Escherichia coli TadA, the wobble-specific tRNA deaminase.

  Biochemistry 20060523

• A fibrinogen deficiency accelerates the initiation of LDL cholesterol-driven atherosclerosis via thrombin generation and platelet activation in genetically predisposed mice.

  Blood 20060515

• Nuclear and cytoplasmic AID in extrafollicular and germinal center B cells.

  Blood 20060515

• Unstructured RNA is a substrate for tRNase Z.

  Biochemistry 20060502

• Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries.

  RNA (New York, N.Y.) 20060501

• High-performance liquid chromatographic method for the determination of gemcitabine and 2',2'-difluorodeoxyuridine in plasma and tissue culture media.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• APOBEC3G DNA deaminase acts processively 3' --> 5' on single-stranded DNA.

  Nature structural & molecular biology 20060501

• Transport of nucleosides across the Plasmodium falciparum parasite plasma membrane has characteristics of PfENT1.

  Molecular microbiology 20060501

• APOBEC deaminases as cellular antiviral factors: a novel natural host defense mechanism.

  Medical science monitor : international medical journal of experimental and clinical research 20060501

• Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies.

  PLoS pathogens 20060501

• Dancin' deaminase.

  Nature structural & molecular biology 20060501

• Cellular pharmacology of gemcitabine.

  Annals of oncology : official journal of the European Society for Medical Oncology 20060501

• Quality evaluation of Cordyceps through simultaneous determination of eleven nucleosides and bases by RP-HPLC.

  Journal of separation science 20060501

• Review: recent clinical trials in epigenetic therapy.

  Reviews on recent clinical trials 20060501

• Innate cellular defenses of APOBEC3 cytidine deaminases and viral counter-defenses.

  Current opinion in HIV and AIDS 20060501

• Isolation and characterization of a scFv antibody specific for tumor endothelial marker 1 (TEM1), a new reagent for targeted tumor therapy.

  Cancer letters 20060428

• [Search for mitochondrial DNA T4291C mutation in Hungarian patients with metabolic syndrome].

  Orvosi hetilap 20060416

• Immunoglobulin heavy chain locus events and expression of activation-induced cytidine deaminase in epithelial breast cancer cell lines.

  Cancer research 20060415

• Electrodeposited sol-gel-imprinted sensing film for cytidine recognition on Au-electrode surface.

  Talanta 20060415

• Synthesis of 3'-beta-carbamoylmethylcytidine (CAMC) and its derivatives as potential antitumor agents.

  Organic & biomolecular chemistry 20060407

• The catalytic activity of REV1 is employed during immunoglobulin gene diversification in DT40.

  Molecular immunology 20060401

• Episomal vectors to monitor and induce somatic hypermutation in human Burkitt-Lymphoma cell lines.

  Molecular immunology 20060401

• Impaired class switch recombination (CSR) in Waldenstrom macroglobulinemia (WM) despite apparently normal CSR machinery.

  Blood 20060401

• Authors reply to I.B. Rogozin and Y.I. Pavlov: 'The cytidine deaminase AID exhibits similar functional properties in yeast and mammals'.

  Molecular immunology 20060401

• Biased dA/dT somatic hypermutation as regulated by the heavy chain intronic iEmu enhancer and 3'Ealpha enhancers in human lymphoblastoid B cells.

  Molecular immunology 20060401

• Insight into the CSA tensors of nucleobase carbons in RNA polynucleotides from solution measurements of residual CSA: towards new long-range orientational constraints.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20060401

• Identification of functional single nucleotide polymorphism haplotypes in the cytidine deaminase promoter.

  Human genetics 20060401

• Decoupling of normal CD40/interleukin-4 immunoglobulin heavy chain switch signal leads to genomic instability in SGH-MM5 and RPMI 8226 multiple myeloma cell lines.

  Leukemia 20060401

• AID in somatic hypermutation and class switch recombination.

  Current opinion in immunology 20060401

• Genes encoding ribonucleoside hydrolase 1 and 2 from Corynebacterium ammoniagenes.

  Microbiology (Reading, England) 20060401

• Diversified bursal medullary B cells survive and expand independently after depletion following neonatal infectious bursal disease virus infection.

  Immunology 20060401

• Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine.

  Cancer research 20060401

• Intracellular restriction factors in mammalian cells--An ancient defense system finds a modern foe.

  Current HIV research 20060401

• Defects of class-switch recombination.

  The Journal of allergy and clinical immunology 20060401

• Formulation, quality control and shelf life of the experimental cytostatic drug cyclopentenyl cytosine.

  Drug development and industrial pharmacy 20060401

• HIV pathogenesis: knowledge gained after two decades of research.

  Advances in dental research 20060401

• An overview of cytidine deaminases.

  International journal of hematology 20060401

• The dark side of activation-induced cytidine deaminase: relationship with leukemia and beyond.

  International journal of hematology 20060401

• Lentiviral Vif: viral hijacker of the ubiquitin-proteasome system.

  International journal of hematology 20060401

• APOBEC family proteins: novel antiviral innate immunity.

  International journal of hematology 20060401

• APOBEC3 cytidine deaminases: distinct antiviral actions along the retroviral life cycle.

  The Journal of biological chemistry 20060331

• Directed DNA deamination by AID/APOBEC3 in immunity.

  Current biology : CB 20060321

• Crystal structure of a bifunctional deaminase and reductase from Bacillus subtilis involved in riboflavin biosynthesis.

  The Journal of biological chemistry 20060317

• AID expression identifies interfollicular large B cells as putative precursors of mature B-cell malignancies.

  Blood 20060315

• Gemcitabine pharmacogenomics: cytidine deaminase and deoxycytidylate deaminase gene resequencing and functional genomics.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20060315

• Anti-viral protein APOBEC3G is induced by interferon-alpha stimulation in human hepatocytes.

  Biochemical and biophysical research communications 20060310

• Synthesis and anti-HIV activity of D- and L-thietanose nucleosides.

  Journal of medicinal chemistry 20060309

• APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons.

  Current biology : CB 20060307

• Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

  Nature 20060302

• MDM2 can interact with the C-terminus of AID but it is inessential for antibody diversification in DT40 B cells.

  Molecular immunology 20060301

• The cytidine deaminase AID exhibits similar functional properties in yeast and mammals.

  Molecular immunology 20060301

• Pyrrolo-C as a fluorescent probe for monitoring RNA secondary structure formation.

  RNA (New York, N.Y.) 20060301

• Validation of real-time reverse-transcription-polymerase chain reaction for quantification of capecitabine-metabolizing enzymes.

  Analytical biochemistry 20060301

• Seasonal changes of nucleotides in mussel (Mytilus galloprovincialis) mantle tissue.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20060301

• Feline lentivirus evolution in cross-species infection reveals extensive G-to-A mutation and selection on key residues in the viral polymerase.

  Journal of virology 20060301

• Facial nerve paralysis after impacted lower third molar surgery: a literature review and case report.

  Medicina oral, patologia oral y cirugia bucal 20060301

• Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines.

  Cancer research 20060301

• Editing of hnRNP K protein mRNA in colorectal adenocarcinoma and surrounding mucosa.

  British journal of cancer 20060227

• Cytidine 5'-monophosphate (CMP)-induced structural changes in a multifunctional sialyltransferase from Pasteurella multocida.

  Biochemistry 20060221

• The novel nucleoside analog R1479 (4'-azidocytidine) is a potent inhibitor of NS5B-dependent RNA synthesis and hepatitis C virus replication in cell culture.

  The Journal of biological chemistry 20060217

• 3'-N-Alkylamino-3'-deoxy-ara-uridines: a new class of potential inhibitors of ribonuclease A and angiogenin.

  Bioorganic & medicinal chemistry 20060215

• Targeted cross-linking of the human beta-globin gene in living cells mediated by a triple helix forming oligonucleotide.

  Biochemistry 20060214

• Tuning the reactivity of osmium(II) and ruthenium(II) arene complexes under physiological conditions.

  Journal of the American Chemical Society 20060208

• Expression of APOBEC2 is transcriptionally regulated by NF-kappaB in human hepatocytes.

  FEBS letters 20060206

• Quantitative determination of zebularine (NSC 309132), a DNA methyltransferase inhibitor, and three metabolites in murine plasma by high-performance liquid chromatography coupled with on-line radioactivity detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060202

• The cytidine deaminases AID and APOBEC-1 exhibit distinct functional properties in a novel yeast selectable system.

  Molecular immunology 20060201

• Simultaneous expression of apolipoprotein B mRNA editing enzyme and scavenger receptor BI mediated by a therapeutic gene expression system.

  Atherosclerosis 20060201

• Identification of a ubiquitously active promoter of the murine activation-induced cytidine deaminase (AICDA) gene.

  Molecular immunology 20060201

• The novel DNA methylation inhibitor zebularine is effective against the development of murine T-cell lymphoma.

  Blood 20060201

• Angiostatic activity of DNA methyltransferase inhibitors.

  Molecular cancer therapeutics 20060201

• Cellular restriction factors affecting the early stages of HIV replication.

  Current HIV/AIDS reports 20060201

• The correlation of RNase A enzymatic activity with the changes in the distance between Nepsilon2-His12 and N delta1-His119 upon addition of stabilizing and destabilizing salts.

  The protein journal 20060201

• Epigenetics provides a new generation of oncogenes and tumour-suppressor genes.

  British journal of cancer 20060130

• AID-dependent histone acetylation is detected in immunoglobulin S regions.

  The Journal of experimental medicine 20060123

• Ubiquitination of APOBEC3 proteins by the Vif-Cullin5-ElonginB-ElonginC complex.

  Virology 20060120

• H2AX prevents DNA breaks from progressing to chromosome breaks and translocations.

  Molecular cell 20060120

• RNA editing sites in plant mitochondria can share cis-elements.

  FEBS letters 20060109

• Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo.

  Circulation 20060103

• Functional expression of the CMP-sialic acid transporter in Escherichia coli and its identification as a simple mobile carrier.

  Glycobiology 20060101

• Cyclopentenyl cytosine-induced activation of deoxycytidine kinase increases gemcitabine anabolism and cytotoxicity in neuroblastoma.

  Cancer chemotherapy and pharmacology 20060101

• Zebularine metabolism by aldehyde oxidase in hepatic cytosol from humans, monkeys, dogs, rats, and mice: influence of sex and inhibitors.

  Bioorganic & medicinal chemistry 20060101

• Evolution of class switch recombination function in fish activation-induced cytidine deaminase, AID.

  International immunology 20060101

• Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination.

  Trends in genetics : TIG 20060101

• Analysis of urinary nucleosides. V. Identification of urinary pyrimidine nucleosides by liquid chromatography/electrospray mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20060101

• Simultaneous genotyping of indels and SNPs by mass spectroscopy.

  Journal of the American Society for Mass Spectrometry 20060101

• Characterization of a bifunctional cytidine 5'-monophosphate N-acetylneuraminic acid synthetase cloned from Streptococcus agalactiae.

  Biotechnology letters 20060101

• The interaction between C75 of tRNA and the A loop of the ribosome stimulates peptidyl transferase activity.

  RNA (New York, N.Y.) 20060101

• Erythrocyte membrane acetylcholinesterase activity in subjects with MTHFR 677C-->T genotype.

  Clinical chemistry and laboratory medicine 20060101

• Adding pharmacogenomics to the development of new marine-derived anticancer agents.

  Journal of translational medicine 20060101

• Inhaled nitric oxide alleviates hyperoxia suppressed phosphatidylcholine synthesis in endotoxin-induced injury in mature rat lungs.

  Respiratory research 20060101

• Review of 'the Twelfth West Coast Retrovirus Meeting' and 'the Twenty-third Annual Symposium on Nonhuman Primate Models for AIDS'.

  AIDS research and therapy 20060101

• Retroviral elements and their hosts: insertional mutagenesis in the mouse germ line.

  PLoS genetics 20060101

• Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines.

  Cancer cell international 20060101

• Patterns of evolution of host proteins involved in retroviral pathogenesis.

  Retrovirology 20060101

• Phase I study of intermittent and chronomodulated oral therapy with capecitabine in patients with advanced and/or metastatic cancer.

  BMC cancer 20060101

• Hydralazine target: from blood vessels to the epigenome.

  Journal of translational medicine 20060101

• Cytidine and uridine increase striatal CDP-choline levels without decreasing acetylcholine synthesis or release.

  Cellular and molecular neurobiology 20060101

• [Mg2+ cation initiates the conversion of nucleoside triphosphate to nucleoside monophospate through a radical mechanism. Quantum molecular dynamics simulation].

  Biofizika 20060101

• Transcriptional control of activation-induced cytidine deaminase and error-prone DNA polymerases is functionally mature in the B cells of infants at birth.

  Human immunology 20060101

• Cytidine 5'-diphosphocholine restores blood flow of superior mesenteric and renal arteries and prolongs survival time in haemorrhaged anaesthetized rats.

  Clinical and experimental pharmacology & physiology 20060101

• A quantum chemical study of the catalysis for cytidine deaminase: contribution of the extra water molecule.

  Journal of chemical information and modeling 20060101

• Keystone 2006. Steady progress presented and discussed at the annual Keystone Symposia on HIV.

  IAVI report : newsletter on international AIDS vaccine research 20060101

• A phase II trial of a biweekly combination of paclitaxel and gemcitabine in metastatic breast cancer.

  BMC cancer 20060101

• Characterization of the ribonuclease activity on the skin surface.

  Genetic vaccines and therapy 20060101

• Locked nucleoside analogues expand the potential of DNAzymes to cleave structured RNA targets.

  BMC molecular biology 20060101

• Molecular pathopharmacology of 5-HT2C receptors and the RNA editing in the brain.

  Journal of pharmacological sciences 20060101

• The yfhQ gene of Escherichia coli encodes a tRNA:Cm32/Um32 methyltransferase.

  BMC molecular biology 20060101

• Epigenetics of gene expression in human hepatoma cells: expression profiling the response to inhibition of DNA methylation and histone deacetylation.

  BMC genomics 20060101

• Metabolic engineering of microbes for oligosaccharide and polysaccharide synthesis.

  Microbial cell factories 20060101

• L1 retrotransposons in human cancers.

  Journal of biomedicine & biotechnology 20060101

• DNA methyltransferase probing of DNA-protein interactions.

  Methods in molecular biology (Clifton, N.J.) 20060101

• A simple and efficient synthesis of puromycin, 2,2'-anhydro-pyrimidine nucleosides, cytidines and 2',3'-anhydroadenosine from 3',5'-O-sulfinyl xylo-nucleosides.

  Nucleosides, nucleotides & nucleic acids 20060101

• Antibody diversification: mutational mechanisms and oncogenesis.

  Immunologic research 20060101

• Tumor suppressor gene methylation in follicular lymphoma: a comprehensive review.

  Molecular cancer 20060101

• Inhibition of hepatitis C replicon RNA synthesis by beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine: a specific inhibitor of hepatitis C virus replication.

  Antiviral chemistry & chemotherapy 20060101

• Vaccinia virus replication is not affected by APOBEC3 family members.

  Virology journal 20060101

• An analysis of mobile genetic elements in three Plasmodium species and their potential impact on the nucleotide composition of the P. falciparum genome.

  BMC genomics 20060101

• Persistent resistance to HIV-1 infection in CD4 T cells from exposed uninfected Vietnamese individuals is mediated by entry and post-entry blocks.

  Retrovirology 20060101

• Maize haplotype with a helitron-amplified cytidine deaminase gene copy.

  BMC genetics 20060101

• The conserved protein kinase-A target motif in synapsin of Drosophila is effectively modified by pre-mRNA editing.

  BMC neuroscience 20060101

• Non coding RNA and brain.

  BMC neuroscience 20060101

• Systematic assignment of thermodynamic constraints in metabolic network models.

  BMC bioinformatics 20060101

• A strategy for selective N-acylation of purine and pyrimidine bases of deoxy and ribo nucleosides.

  Nucleic acids symposium series (2004) 20060101

• Synthesis of deoxycytidine derivatives and their use for the selective photo crosslinking with 5-methylcytosine.

  Nucleic acids symposium series (2004) 20060101

• An apoptotic pathway of 3'-Ethynylcytidine(ECyd) involving the inhibition of RNA synthesis mediated by RNase L.

  Nucleic acids symposium series (2004) 20060101

• X-Ray analyses of DNA duplexes stabilized by bicyclic-C residues.

  Nucleic acids symposium series (2004) 20060101

• Comparative analysis of hepatitis C virus phylogenies from coding and non-coding regions: the 5' untranslated region (UTR) fails to classify subtypes.

  Virology journal 20060101

• [The innate antiretroviral defense of human cells, based on the DNA editing].

  Postepy biochemii 20060101

• Regulation of two key nuclear enzymatic activities by the 7SK small nuclear RNA.

  Cold Spring Harbor symposia on quantitative biology 20060101

• Modification of Cepsilon mRNA expression by EBV-encoded latent membrane protein 1.

  Mediators of inflammation 20060101

• Paradigm development: comparative and predictive 3D modeling of HIV-1 Virion Infectivity Factor (Vif).

  Bioinformation 20060101

• Regulation of luteinizing hormone receptor expression: evidence of translational suppression in vitro by a hormonally regulated mRNA-binding protein and its endogenous association with luteinizing hormone receptor mRNA in the ovary.

  The Journal of biological chemistry 20051230

• Differential interactions of G-proteins and adenylyl cyclase with nucleoside 5'-triphosphates, nucleoside 5'-[gamma-thio]triphosphates and nucleoside 5'-[beta,gamma-imido]triphosphates.

  Biochemical pharmacology 20051219

• The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia.

  British journal of cancer 20051212

• Resistance to cytarabine and gemcitabine and in vitro selection of transduced cells after retroviral expression of cytidine deaminase in human hematopoietic progenitor cells.

  Leukemia 20051201

• [Outline of HIV replication and its cellular factors: the track of an invader in the cell].

  Uirusu 20051201

• [Antiviral defense by APOBEC3 family proteins].

  Uirusu 20051201

• The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation.

  Nature 20051124

• The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation.

  The EMBO journal 20051102

• Simultaneous high performance liquid chromatographic separation of purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism.

  Clinical biochemistry 20051101

• The folding and unfolding kinetics of the i-motif structure formed by the C-rich strand of human telomere DNA.

  Chembiochem : a European journal of chemical biology 20051101

• Cutting edge: double-stranded DNA breaks in the IgV region gene were detected at lower frequency in affinity-maturation impeded GANP-/- mice.

  Journal of immunology (Baltimore, Md. : 1950) 20051101

• The BAFF/APRIL system in systemic autoimmune diseases with a special emphasis on Sjögren's syndrome.

  Scandinavian journal of immunology 20051101

• Activation-induced cytidine deaminase and CD38 expression in B-cell chronic lymphocytic leukemia.

  Clinical lymphoma & myeloma 20051101

• [High intestinal transport activity for nucleosides in cattle: a synopsis].

  DTW. Deutsche tierarztliche Wochenschrift 20051101

• Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy.

  Annals of the New York Academy of Sciences 20051101

• Apoptosis induced by nucleosides in the human hepatoma HepG2.

  World journal of gastroenterology 20051028

• Stable and selective formation of hoogsteen-type triplexes and duplexes using twisted intercalating nucleic acids (TINA) prepared via postsynthetic Sonogashira solid-phase coupling reactions.

  Journal of the American Chemical Society 20051026

• Silicon chelation in aqueous and nonaqueous media: the furanoidic diol approach.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20051021

• The DNA demethylating 5-azaC induces endoreduplication in cultured Chinese hamster cells.

  Mutation research 20051015

• RNA challenges for computational chemists.

  Biochemistry 20051011

• Oral uridine-5'-monophosphate (UMP) increases brain CDP-choline levels in gerbils.

  Brain research 20051005

• T Lymphocytes transduced with a lentiviral vector expressing F12-Vif are protected from HIV-1 infection in an APOBEC3G-independent manner.

  Molecular therapy : the journal of the American Society of Gene Therapy 20051001

• Functional expression of the gene encoding cytidine triphosphate synthetase from Plasmodium falciparum which contains two novel sequences that are potential antimalarial targets.

  Molecular and biochemical parasitology 20051001

• Genetic determinants of cancer drug efficacy and toxicity: practical considerations and perspectives.

  Anti-cancer drugs 20051001

• Human splenic marginal zone B cells lack expression of activation-induced cytidine deaminase.

  European journal of immunology 20051001

• Splenic marginal zone B cells in humans: where do they mutate their Ig receptor?

  European journal of immunology 20051001

• Enzymatic properties of serine 93 mutants of RNase Rh from Rhizopus niveus. A trial to alter the base preference of RNase Rh.

  Biological & pharmaceutical bulletin 20051001

• Innovative approaches to the clinical development of DNA methylation inhibitors as epigenetic remodeling drugs.

  Seminars in oncology 20051001

• Perisinusoidal B cells in the bone marrow participate in T-independent responses to blood-borne microbes.

  Immunity 20051001

• Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer.

  Molecular cancer therapeutics 20051001

• Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine.

  Molecular cancer therapeutics 20051001

• Enzymatic synthesis of cytidine 5'-monophospho-N-acetylneuraminic acid.

  Bioscience, biotechnology, and biochemistry 20051001

• HIV-1 Vif: HIV's weapon against the cellular defense factor APOBEC3G.

  Current HIV research 20051001

• Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G.

  The Journal of biological chemistry 20050923

• Nucleic acid related compounds. 127. Selective N-deacylation of N,O-peracylated nucleosides in superheated methanol.

  The Journal of organic chemistry 20050902

• Cytidine deaminase in polymyalgia rheumatica and elderly onset rheumatoid arthritis.

  Clinical rheumatology 20050901

• AID binds to transcription-induced structures in c-MYC that map to regions associated with translocation and hypermutation.

  Oncogene 20050901

• Human APOBEC3B is a potent inhibitor of HIV-1 infectivity and is resistant to HIV-1 Vif.

  Virology 20050901

• APOBEC4, a new member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases predicted by computational analysis.

  Cell cycle (Georgetown, Tex.) 20050901

• Extensive editing of a small fraction of human T-cell leukemia virus type 1 genomes by four APOBEC3 cytidine deaminases.

  The Journal of general virology 20050901

• Editing of plastid RNA in Arabidopsis thaliana ecotypes.

  The Plant journal : for cell and molecular biology 20050901

• Activation induced cytidine deaminase expression in lymphocyte predominant Hodgkin lymphoma.

  Journal of clinical pathology 20050901

• Natural variation in Vif: differential impact on APOBEC3G/3F and a potential role in HIV-1 diversification.

  PLoS pathogens 20050901

• [Identification of 5 constituents of the aqueous extract of Isatis indigotica by HPLC-MS2].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050901

• [Identification of two novel mutations in ADAMTS13 gene in a patient with hereditary thrombotic thrombocytopenic purpura].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20050901

• Structural dynamics of precursor and product of the RNA enzyme from the hepatitis delta virus as revealed by molecular dynamics simulations.

  Journal of molecular biology 20050826

• The burden borne by urease.

  Journal of the American Chemical Society 20050810

• Mannosamine supplementation extends the N-acetylglucosaminylation of recombinant human secreted alkaline phosphatase produced in Trichoplusia ni (cabbage looper) insect cell cultures.

  Biotechnology and applied biochemistry 20050801

• Improving the biosafety of cell sorting by adaptation of a cell sorting system to a biosafety cabinet.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20050801

• APOBEC-mediated interference with hepadnavirus production.

  Hepatology (Baltimore, Md.) 20050801

• Copper(II) complexes of tridentate pyridylmethylethylenediamines: role of ligand steric hindrance on DNA binding and cleavage.

  Journal of inorganic biochemistry 20050801

• Identification of APOBEC3B as a potential target for the graft-versus-lymphoma effect by SEREX in a patient with mantle cell lymphoma.

  British journal of haematology 20050801

• Lentiviral vectors and antiretroviral intrinsic immunity.

  Human gene therapy 20050801

• [Mice transduced with double-mutant dihydrofolate reductase-cytidine deaminase fusion gene attained protection from high dose chemotherapy].

  Zhonghua wai ke za zhi [Chinese journal of surgery] 20050801

• Prolonged fixed dose rate infusion of gemcitabine with autologous haemopoietic support in advanced pancreatic adenocarcinoma.

  British journal of cancer 20050711

• Signature of B-CLL with different prognosis by Shrunken centroids of surface antigen expression profiling.

  Journal of cellular physiology 20050701

• Cellular and pharmacogenetics foundation of synergistic interaction of pemetrexed and gemcitabine in human non-small-cell lung cancer cells.

  Molecular pharmacology 20050701

• Structure alignment via Delaunay tetrahedralization.

  Proteins 20050701

• Docking simulation with a purine nucleoside specific homology model of deoxycytidine kinase, a target enzyme for anticancer and antiviral therapy.

  Bioorganic & medicinal chemistry 20050701

• Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells.

  Biochemical pharmacology 20050701

• Characterization of an ecto-ATPase activity in Cryptococcus neoformans.

  FEMS yeast research 20050701

• A family with a novel frameshift mutation in the PMP22 gene (c.433_434insC) causing a phenotype of hereditary neuropathy with liability to pressure palsies.

  Neuromuscular disorders : NMD 20050701

• X irradiation induces the proapoptotic state independent of the loss of clonogenic ability in Chinese hamster V79 cells.

  Radiation research 20050701

• The cell cycle-regulated genes of Schizosaccharomyces pombe.

  PLoS biology 20050701

• Decitabine dosing schedules.

  Seminars in hematology 20050701

• Pharmacology of 5-Aza-2'-deoxycytidine (decitabine).

  Seminars in hematology 20050701

• Regulated production and anti-HIV type 1 activities of cytidine deaminases APOBEC3B, 3F, and 3G.

  AIDS research and human retroviruses 20050701

• Reduction of ribonucleosides to 2'-deoxyribonucleosides.

  Current protocols in nucleic acid chemistry 20050701

• Mechanisms underlying the effects of LPS and activation-induced cytidine deaminase on IgA isotype expression.

  Molecules and cells 20050630

• Human APOBEC3G incorporation into murine leukemia virus particles.

  Virology 20050620

• Deoxyuridine is generated preferentially in the nontranscribed strand of DNA from cells expressing activation-induced cytidine deaminase.

  Journal of immunology (Baltimore, Md. : 1950) 20050615

• Enhancement of in vitro and in vivo tumor cell radiosensitivity by the DNA methylation inhibitor zebularine.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050615

• Pharmacokinetics of 5-azacitidine administered with phenylbutyrate in patients with refractory solid tumors or hematologic malignancies.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050610

• Abnormalities in uridine homeostatic regulation and pyrimidine nucleotide metabolism as a consequence of the deletion of the uridine phosphorylase gene.

  The Journal of biological chemistry 20050603

• Hydrolysis of capecitabine to 5'-deoxy-5-fluorocytidine by human carboxylesterases and inhibition by loperamide.

  The Journal of pharmacology and experimental therapeutics 20050601

• Analysis of class switch recombination and somatic hypermutation in patients affected with autosomal dominant hyper-IgM syndrome type 2.

  Clinical immunology (Orlando, Fla.) 20050601

• RNA editing produces glycine receptor alpha3(P185L), resulting in high agonist potency.

  Nature neuroscience 20050601

• Absence of immunoglobulin class switch in primary lymphomas of the central nervous system.

  The American journal of pathology 20050601

• Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation.

  Cancer research 20050601

• Profile: Michael Malim.

  Nature medicine 20050601

• Normal ICOS, ICOSL and AID alleles in Danish patients with common variable immunodeficiency.

  Scandinavian journal of immunology 20050601

• DNA lesions and repair in immunoglobulin class switch recombination and somatic hypermutation.

  Annals of the New York Academy of Sciences 20050601

• Expression, purification, crystallization and preliminary X-ray analysis of a nucleoside kinase from the hyperthermophile Methanocaldococcus jannaschii.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20050601

• Structure-activity relationships of dinucleotides: Potent and selective agonists of P2Y receptors.

  Purinergic signalling 20050601

• Structural bioinformatics-based design of selective, irreversible kinase inhibitors.

  Science (New York, N.Y.) 20050527

• Purification and characterization of RihC, a xanthosine-inosine-uridine-adenosine-preferring hydrolase from Salmonella enterica serovar Typhimurium.

  Biochimica et biophysica acta 20050525

• The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours.

  Nature 20050519

• Plasma pharmacokinetics, oral bioavailability, and interspecies scaling of the DNA methyltransferase inhibitor, zebularine.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050515

• (E)-5-[2-(methoxycarbonyl)ethenyl]cytidine as a chemical actinometer for germicidal UV radiation.

  Environmental science & technology 20050515

• Ubiquitination of APOBEC3G by an HIV-1 Vif-Cullin5-Elongin B-Elongin C complex is essential for Vif function.

  The Journal of biological chemistry 20050513

• Synthesis and triplex forming properties of pyrrolidino pseudoisocytidine containing oligodeoxynucleotides.

  Organic & biomolecular chemistry 20050507

• Cellular APOBEC3G restricts HIV-1 infection in resting CD4+ T cells.

  Nature 20050505

• B lymphocyte stimulator activates p38 mitogen-activated protein kinase in human Ig class switch recombination.

  American journal of respiratory cell and molecular biology 20050501

• Aberrant somatic hypermutation and expression of activation-induced cytidine deaminase mRNA in mediastinal large B-cell lymphoma.

  British journal of haematology 20050501

• The influence of immune complex-bearing follicular dendritic cells on the IgM response, Ig class switching, and production of high affinity IgG.

  Journal of immunology (Baltimore, Md. : 1950) 20050501

• Hypermutation rate normalized by chronological time.

  Journal of immunology (Baltimore, Md. : 1950) 20050501

• The contested role of uracil DNA glycosylase in immunoglobulin gene diversification.

  Trends in genetics : TIG 20050501

• Guanine-adenine bias: a general property of retroid viruses that is unrelated to host-induced hypermutation.

  Trends in genetics : TIG 20050501

• Sensitivity to gemcitabine and its metabolizing enzymes in neuroblastoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050501

• Absence of cardiotoxicity of the experimental cytotoxic drug cyclopentenyl cytosine (CPEC) in rats.

  Archives of toxicology 20050501

• Possible antitumor activity of 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106) against an established gemcitabine (dFdCyd)-resistant human pancreatic cancer cell line.

  Cancer science 20050501

• Purine nucleosides stimulate Na/K ATPase, and prolong survival in hemorrhagic shock.

  The Journal of trauma 20050501

• [Application of urinary nucleosides in the diagnosis and surgical monitoring of colorectal cancer].

  Zhonghua wai ke za zhi [Chinese journal of surgery] 20050501

• Crystal structure of tRNA adenosine deaminase (TadA) from Aquifex aeolicus.

  The Journal of biological chemistry 20050422

• Mutation frequencies and AID activation state in B-cell lymphomas from Ung-deficient mice.

  Oncogene 20050421

• 1-Methyl-3H-pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-ones. Design, synthesis, and biological activity of new antitumor agents.

  Journal of medicinal chemistry 20050421

• Cytidinediphosphocholine (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly.

  The Cochrane database of systematic reviews 20050418

• The tyrosine kinases Fyn and Hck favor the recruitment of tyrosine-phosphorylated APOBEC3G into vif-defective HIV-1 particles.

  Biochemical and biophysical research communications 20050415

• Allergen drives class switching to IgE in the nasal mucosa in allergic rhinitis.

  Journal of immunology (Baltimore, Md. : 1950) 20050415

• Inhibition of a yeast LTR retrotransposon by human APOBEC3 cytidine deaminases.

  Current biology : CB 20050412

• Cytidine deamination and resistance to retroviral infection: towards a structural understanding of the APOBEC proteins.

  Virology 20050410

• Differential expression of activation-induced cytidine deaminase (AID) in nodular lymphocyte-predominant and classical Hodgkin lymphoma.

  The Journal of pathology 20050401

• Synthesis and biological evaluation of branched and conformationally restricted analogs of the anticancer compounds 3'-C-ethynyluridine (EUrd) and 3'-C-ethynylcytidine (ECyd).

  Bioorganic & medicinal chemistry 20050401

• Quantitative RT-PCR analysis of activation-induced cytidine deaminase expression in tissue samples from mantle cell lymphoma and B-cell chronic lymphocytic leukemia patients.

  Blood 20050401

• An update on the role of translesion synthesis DNA polymerases in Ig hypermutation.

  Trends in immunology 20050401

• Jun N-terminal kinase is essential for CD40-mediated IgE class switching in B cells.

  The Journal of allergy and clinical immunology 20050401

• Severe drug toxicity associated with a single-nucleotide polymorphism of the cytidine deaminase gene in a Japanese cancer patient treated with gemcitabine plus cisplatin.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050401

• Stage- and site-specific DNA demethylation during neural cell development from embryonic stem cells.

  Journal of neurochemistry 20050401

• Reaction of glyoxal with 2'-deoxyguanosine, 2'-deoxyadenosine, 2'-deoxycytidine, cytidine, thymidine, and calf thymus DNA: identification of DNA adducts.

  Chemical research in toxicology 20050401

• Chemical constituents of the fruits of Morinda citrifolia (Noni) and their antioxidant activity.

  Journal of natural products 20050401

• The retroviral hypermutation specificity of APOBEC3F and APOBEC3G is governed by the C-terminal DNA cytosine deaminase domain.

  The Journal of biological chemistry 20050325

• Different isoforms of BSAP regulate expression of AID in normal and chronic lymphocytic leukemia B cells.

  Blood 20050315

• Complementary function of the two catalytic domains of APOBEC3G.

  Virology 20050315

• Newly identified host factors modulate HIV replication.

  Immunology letters 20050315

• A phase I clinical and pharmacokinetic study of capecitabine (Xeloda) and irinotecan combination therapy (XELIRI) in patients with metastatic gastrointestinal tumours.

  British journal of cancer 20050314

• HIV-1 Vif can directly inhibit apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G-mediated cytidine deamination by using a single amino acid interaction and without protein degradation.

  The Journal of biological chemistry 20050311

• Origin of tight binding of a near-perfect transition-state analogue by cytidine deaminase: implications for enzyme catalysis.

  Journal of the American Chemical Society 20050309

• Analysis of HIV-1 viral infectivity factor-mediated proteasome-dependent depletion of APOBEC3G: correlating function and subcellular localization.

  The Journal of biological chemistry 20050304

• Tuning single nucleotide discrimination in polymerase chain reactions (PCRs): synthesis of primer probes bearing polar 4'-C-modifications and their application in allele-specific PCR.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20050304

• Molecular analysis of a large cohort of patients with the hyper immunoglobulin M (IgM) syndrome.

  Blood 20050301

• Phosphorylation of Cytidine, Deoxycytidine, and Their Analog Monophosphates by Human UMP/CMP Kinase Is Differentially Regulated by ATP and Magnesium.

  Molecular pharmacology 20050301

• Methylation protects cytidines from AID-mediated deamination.

  Molecular immunology 20050301

• Model platinum nucleobase and nucleoside complexes and antitumor activity: X-ray crystal structure of [PtIV(trans-1R,2R-diaminocyclohexane)trans-(acetate)2(9-ethylguanine)Cl]NO3.H2O.

  Journal of inorganic biochemistry 20050301

• Enhancement of antineoplastic action of 5-aza-2'-deoxycytidine by zebularine on L1210 leukemia.

  Anti-cancer drugs 20050301

• Maintenance of the diacylglycerol level in the Golgi apparatus by the Nir2 protein is critical for Golgi secretory function.

  Nature cell biology 20050301

• Reward versus risk: DNA cytidine deaminases triggering immunity and disease.

  Biochemistry 20050301

• G to A hypermutation of hepatitis B virus.

  Hepatology (Baltimore, Md.) 20050301

• Structure of human uridine-cytidine kinase 2 determined by SIRAS using a rotating-anode X-ray generator and a single samarium derivative.

  Acta crystallographica. Section D, Biological crystallography 20050301

• Accurate measurement of 15N-13C residual dipolar couplings in nucleic acids.

  Journal of biomolecular NMR 20050301

• Identification and functional characterization of variants in human concentrative nucleoside transporter 3, hCNT3 (SLC28A3), arising from single nucleotide polymorphisms in coding regions of the hCNT3 gene.

  Pharmacogenetics and genomics 20050301

• Interaction between gemcitabine and topotecan in human non-small-cell lung cancer cells: effects on cell survival, cell cycle and pharmacogenetic profile.

  British journal of cancer 20050227

• Synthesis and evaluation of S-acyl-2-thioethyl esters of modified nucleoside 5'-monophosphates as inhibitors of hepatitis C virus RNA replication.

  Journal of medicinal chemistry 20050224

• Editing at the crossroad of innate and adaptive immunity.

  Science (New York, N.Y.) 20050218

• Synthesis and biological evaluation of nucleobase-modified analogs of the anticancer compounds 3'-C-ethynyluridine (EUrd) and 3'-C-ethynylcytidine (ECyd).

  Bioorganic & medicinal chemistry 20050215

• Antidepressant-like effects of uridine and omega-3 fatty acids are potentiated by combined treatment in rats.

  Biological psychiatry 20050215

• Epigenetic silencing of the human nucleotide excision repair gene, hHR23B, in interleukin-6-responsive multiple myeloma KAS-6/1 cells.

  The Journal of biological chemistry 20050211

• Shape-specific nucleotide binding of single-stranded RNA by the GLD-1 STAR domain.

  Journal of molecular biology 20050211

• Structure of human cytidine deaminase bound to a potent inhibitor.

  Journal of medicinal chemistry 20050210

• Quadruplex-duplex competition in the nuclease hypersensitive element of human c-myc promoter: C to T mutation in C-rich strand enhances duplex association.

  Biochemical and biophysical research communications 20050204

• Reversible switching of immunoglobulin hypermutation machinery in a chicken B cell line.

  Biochemical and biophysical research communications 20050204

• GATA1, cytidine deaminase, and the high cure rate of Down syndrome children with acute megakaryocytic leukemia.

  Journal of the National Cancer Institute 20050202

• Evolution of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases.

  Molecular biology and evolution 20050201

• Structural classification of thioredoxin-like fold proteins.

  Proteins 20050201

• Mutational activity in cell line WEHI-231.

  Immunogenetics 20050201

• Lethal mutagenesis of HIV.

  Virus research 20050201

• The mutation spectrum of purified AID is similar to the mutability index in Ramos cells and in ung(-/-)msh2(-/-) mice.

  Immunogenetics 20050201

• NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor.

  RNA (New York, N.Y.) 20050201

• Hyper-immunoglobulin M syndromes caused by intrinsic B-lymphocyte defects.

  Immunological reviews 20050201

• DNA deamination in immunity.

  Immunological reviews 20050201

• Activation-induced deaminase: controversies and open questions.

  Trends in immunology 20050201

• Formation of conjugate adducts in the reactions of malonaldehyde-acetaldehyde and malonaldehyde-formaldehyde with guanosine.

  Chemical research in toxicology 20050201

• Protecting APOBEC3G: a potential new target for HIV drug discovery.

  Current opinion in investigational drugs (London, England : 2000) 20050201

• The role of viral fitness in HIV pathogenesis.

  Current HIV/AIDS reports 20050201

• APOBEC3G cytidine deaminase inhibits retrotransposition of endogenous retroviruses.

  Nature 20050127

• Antiviral function of APOBEC3G can be dissociated from cytidine deaminase activity.

  Current biology : CB 20050126

• APOBEC3G ubiquitination by Nedd4-1 favors its packaging into HIV-1 particles.

  Journal of molecular biology 20050121

• Phototriggering of caged fluorescent oligodeoxynucleotides.

  Organic letters 20050120

• A pentatricopeptide repeat protein is essential for RNA editing in chloroplasts.

  Nature 20050120

• Exhaustive genotyping of the CEM15 (APOBEC3G) gene and absence of association with AIDS progression in a French cohort.

  The Journal of infectious diseases 20050115

• The double-edged sword of activation-induced cytidine deaminase.

  Journal of immunology (Baltimore, Md. : 1950) 20050115

• Nanocrystal-based bioelectronic coding of single nucleotide polymorphisms.

  Journal of the American Chemical Society 20050112

• Production of infectious SIVagm from human cells requires functional inactivation but not viral exclusion of human APOBEC3G.

  The Journal of biological chemistry 20050107

• Hybridization-promoted and cytidine-selective activation for cross-linking with the use of 2-amino-6-vinylpurine derivatives.

  The Journal of organic chemistry 20050107

• Identification of the activation-induced cytidine deaminase gene from zebrafish: an evolutionary analysis.

  Developmental and comparative immunology 20050101

• Activation-induced cytidine deaminase fails to induce a mutator phenotype in the human pre-B cell line Nalm-6.

  European journal of immunology 20050101

• Improved understanding of human genetic control of HIV pathogenicity.

  Reviews in medical virology 20050101

• A new approach to an AIDS vaccine: creating antibodies to HIV vif will enable apobec3G to turn HIV-infection into a benign problem.

  Medical hypotheses 20050101

• Presence of somatic hypermutation and activation-induced cytidine deaminase in acute lymphoblastic leukemia L2 with t(14;18)(q32;q21).

  European journal of haematology 20050101

• Taxonomic distribution and quantitative analysis of free purine and pyrimidine nucleosides in snake venoms.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050101

• The structure of a rigorously conserved RNA element within the SARS virus genome.

  PLoS biology 20050101

• Gene expression profiling revealed novel mechanism of action of Taxotere and Furtulon in prostate cancer cells.

  BMC cancer 20050101

• Human CD57+ germinal center-T cells are the major helpers for GC-B cells and induce class switch recombination.

  BMC immunology 20050101

• Pathways of pyrimidine salvage in Streptomyces.

  Current microbiology 20050101

• Non-enzymatic in vitro DNA labeling and label immunoquantification.

  Preparative biochemistry & biotechnology 20050101

• Molecular strategies to inhibit HIV-1 replication.

  Retrovirology 20050101

• The Vpr protein from HIV-1: distinct roles along the viral life cycle.

  Retrovirology 20050101

• Cytidine 5'-diphosphocholine (CDP-choline) in stroke and other CNS disorders.

  Neurochemical research 20050101

• Mice have a transcribed L-threonine aldolase/GLY1 gene, but the human GLY1 gene is a non-processed pseudogene.

  BMC genomics 20050101

• Investigation of multiple binding sites on ribonuclease A using nano-electrospray ionization mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20050101

• Cloning of the koi herpesvirus (KHV) gene encoding thymidine kinase and its use for a highly sensitive PCR based diagnosis.

  BMC microbiology 20050101

• Developmentally programmed expression of AID in chicken B cells.

  Developmental and comparative immunology 20050101

• Low dose docosahexaenoic acid protects normal colonic epithelial cells from araC toxicity.

  BMC pharmacology 20050101

• [Assembly and maturation of HIV-1--targets for new anti-HIV compounds].

  Molekuliarnaia genetika, mikrobiologiia i virusologiia 20050101

• Amino acid ester prodrugs of the anticancer agent gemcitabine: synthesis, bioconversion, metabolic bioevasion, and hPEPT1-mediated transport.

  Molecular pharmaceutics 20050101

• [Phorbol 12-myristate 13-acetate inhibits apoptosis in erythroleukemia K562 cells induced by some nucleosides].

  Ontogenez 20050101

• First Dominique Dormont International Conference on 'Host-pathogen interactions in chronic infections - viral and host determinants of HCV, HCMV, and HIV infections'.

  Retrovirology 20050101

• PREP-Mt: predictive RNA editor for plant mitochondrial genes.

  BMC bioinformatics 20050101

• Intracellular immunity to HIV-1: newly defined retroviral battles inside infected cells.

  Retrovirology 20050101

• Lipid nucleoside conjugates for the treatment of cancer.

  Current pharmaceutical design 20050101

• Strain-specific differences in Neisseria gonorrhoeae associated with the phase variable gene repertoire.

  BMC microbiology 20050101

• Comparative pharmacokinetics of Racivir, (+/-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine in rats, rabbits, dogs, monkeys and HIV-infected humans.

  Antiviral chemistry & chemotherapy 20050101

• APOBEC3G & HTLV-1: inhibition without deamination.

  Retrovirology 20050101

• APOBEC3G targets human T-cell leukemia virus type 1.

  Retrovirology 20050101

• Expression of human AID in yeast induces mutations in context similar to the context of somatic hypermutation at G-C pairs in immunoglobulin genes.

  BMC immunology 20050101

• Detection of non-papillary, non-invasive transitional cell G1 carcinoma as revealed by increased DNA instability and other cancer markers.

  European journal of histochemistry : EJH 20050101

• Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human.

  Genome biology 20050101

• Characterization of hepatitis B virus inhibition by novel 2'-fluoro-2',3'-unsaturated beta-D- and L-nucleosides.

  Antiviral chemistry & chemotherapy 20050101

• Transport of thalidomide by the human intestinal caco-2 monolayers.

  European journal of drug metabolism and pharmacokinetics 20050101

• Genetic factors influencing pyrimidine-antagonist chemotherapy.

  The pharmacogenomics journal 20050101

• Use of endogenous retroviral sequences (ERVs) and structural markers for retroviral phylogenetic inference and taxonomy.

  Retrovirology 20050101

• Antibody class switch recombination: roles for switch sequences and mismatch repair proteins.

  Advances in immunology 20050101

• Description of a PCR-based technique for DNA splicing and mutagenesis by producing 5' overhangs with run through stop DNA synthesis utilizing Ara-C.

  BMC biotechnology 20050101

• Guardian of the genome. Research into a different kind of viral defense system may yield powerful treatments and solve some mysteries about HIV.

  IAVI report : newsletter on international AIDS vaccine research 20050101

• Cytidine deaminase activity in Penicillium politans NRC-510.

  Journal of basic microbiology 20050101

• RNAi and RNA-based regulation of immune system function.

  Advances in immunology 20050101

• Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms.

  Retrovirology 20050101

• Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy. The magic of its chemistry and biology.

  Nucleosides, nucleotides & nucleic acids 20050101

• Synthesis and biological evaluation of conformationally restricted and nucleobase-modified analogs of the anticancer compound 3'-C-ethynylcytidine (ECyd).

  Nucleosides, nucleotides & nucleic acids 20050101

• Kilo-scale synthesis process for 2'-O-(2-methoxyethyl)-pyrimidine derivatives.

  Nucleosides, nucleotides & nucleic acids 20050101

• Epigenetics of cervical cancer. An overview and therapeutic perspectives.

  Molecular cancer 20050101

• Immunoglobulin gene diversification.

  Annual review of genetics 20050101

• Studies of the intermediary metabolism in cultured cells of the insect Spodoptera frugiperda using 13C- or 15N-labelled tracers.

  BMC biochemistry 20050101

• Review of the twelfth West Coast Retrovirus Meeting.

  Retrovirology 20050101

• Characterization of 954 bovine full-CDS cDNA sequences.

  BMC genomics 20050101

• What do somatic hypermutation and class switch recombination teach us about chronic lymphocytic leukaemia pathogenesis?

  Current topics in microbiology and immunology 20050101

• Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions.

  Cell research 20050101

• Nucleosides and nucleotides. 232. Synthesis of 2'-C-methyl-4'-thiocytidine: unexpected anomerization of the 2'-keto-4'-thionucleoside precursor.

  Nucleosides, nucleotides & nucleic acids 20050101

• Class switch recombination: an emerging mechanism.

  Current topics in microbiology and immunology 20050101

• Inhibition of the synthesis of apolipoprotein B-containing lipoproteins.

  Handbook of experimental pharmacology 20050101

• Substituent effects on the in situ activation of the double activated cross-linking reaction.

  Nucleic acids symposium series (2004) 20050101

• Synthesis and properties of 2'-O-methyl-4'-thioRNA.

  Nucleic acids symposium series (2004) 20050101

• Substitutions in the Reverse Transcriptase and Protease Genes of HIV-1 Subtype B in Untreated Individuals and Patients Treated With Antiretroviral Drugs.

  Journal of the International AIDS Society 20050101

• Retrovirus restriction factors.

  Molecular cell 20041222

• APOBEC3B and APOBEC3C are potent inhibitors of simian immunodeficiency virus replication.

  The Journal of biological chemistry 20041217

• Green tea polyphenols as inhibitors of ribonuclease A.

  Biochemical and biophysical research communications 20041217

• Ferrocenyl-modified DNA: synthesis, characterization and integration with semiconductor electrodes.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20041217

• Chemoenzymatic synthesis of CMP-sialic acid derivatives by a one-pot two-enzyme system: comparison of substrate flexibility of three microbial CMP-sialic acid synthetases.

  Bioorganic & medicinal chemistry 20041215

• Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming.

  The Journal of biological chemistry 20041210

• Biochemical analysis of hypermutational targeting by wild type and mutant activation-induced cytidine deaminase.

  The Journal of biological chemistry 20041203

• The Escherichia coli Fis promoter is regulated by changes in the levels of its transcription initiation nucleotide CTP.

  The Journal of biological chemistry 20041203

• A novel activation-induced cytidine deaminase gene mutation in a Tunisian family with hyper IgM syndrome.

  European journal of pediatrics 20041201

• Zebularine: a new drug for epigenetic therapy.

  Biochemical Society transactions 20041201

• An evolutionarily conserved target motif for immunoglobulin class-switch recombination.

  Nature immunology 20041201

• A novel anticancer ribonucleoside, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine, enhances radiation-induced cell death in tumor cells.

  Radiation research 20041201

• AID: a very old motif newly recognized.

  Nature immunology 20041201

• Montmorillonite, oligonucleotides, RNA and origin of life.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20041201

• Phosphorylation of a novel SOCS-box regulates assembly of the HIV-1 Vif-Cul5 complex that promotes APOBEC3G degradation.

  Genes & development 20041201

• Specific NEMO mutations impair CD40-mediated c-Rel activation and B cell terminal differentiation.

  The Journal of clinical investigation 20041201

• Blocking HIV-1 Vif restores a natural mechanism of intracellular antiviral defense.

  Current drug targets. Immune, endocrine and metabolic disorders 20041201

• Antibody diversity: one enzyme to rule them all.

  Nature medicine 20041201

• Unedited inhibition of HBV replication by APOBEC3G.

  Journal of hepatology 20041201

• Characterization of the adducts formed in the reactions of glycidamide with thymidine and cytidine.

  Chemical research in toxicology 20041201

• The complete mitochondrial genomes sequences of Asio flammeus and Asio otus and comparative analysis.

  Science in China. Series C, Life sciences 20041201

• Chromatographic separation of nucleosides using a cross-linked xylose isomerase crystal stationary phase.

  Journal of separation science 20041201

• Transport of endogenous nucleosides in guinea pig heart.

  Canadian journal of physiology and pharmacology 20041201

• [How Vif regulates the infectivity of HIV-1].

  Seikagaku. The Journal of Japanese Biochemical Society 20041201

• Isoenzymatic forms of human cytidine deaminase.

  Protein engineering, design & selection : PEDS 20041201

• DNA . RNA heteroduplex containing 8-oxo-7,8-dihydroguanosine: base pairing, structures, and thermodynamic stability.

  Journal of biochemistry and molecular biology 20041130

• Identification and separation of PCR products based on their GC content by denaturing high-performance liquid chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041125

• B cell development leads off with a base hit: dU:dG mismatches in class switching and hypermutation.

  Molecular cell 20041119

• Hairy cell leukemia: at the crossroad of somatic mutation and isotype switch.

  Blood 20041115

• Expression of the AID protein in normal and neoplastic B cells.

  Blood 20041115

• Development and validation of a high-performance liquid chromatography assay and a capillary electrophoresis assay for the analysis of adenosine and the degradation product adenine in infusions.

  Journal of pharmaceutical and biomedical analysis 20041115

• A cluster of metabolic defects caused by mutation in a mitochondrial tRNA.

  Science (New York, N.Y.) 20041112

• A new and efficient synthetic method for 15N3-labeled cytosine nucleosides: Dimroth rearrangement of cytidine N3-oxides.

  The Journal of organic chemistry 20041112

• Three-dimensional structure of the R115E mutant of T4-bacteriophage 2'-deoxycytidylate deaminase.

  Biochemistry 20041102

• p53 polymorphism and p21WAF1/CIP1 haplotype in the intestinal gastric cancer and the precancerous lesions.

  Carcinogenesis 20041101

• The serine repeat antigen (SERA) gene family phylogeny in Plasmodium: the impact of GC content and reconciliation of gene and species trees.

  Molecular biology and evolution 20041101

• CPEC induces erythroid differentiation of human myeloid leukemia K562 cells through CTP depletion and p38 MAP kinase.

  Leukemia 20041101

• AID is expressed in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas and is not correlated with intraclonal heterogeneity.

  Leukemia 20041101

• A growth study of Coxiella burnetii Nine Mile Phase I and Phase II in fibroblasts.

  FEMS immunology and medical microbiology 20041101

• APOBEC3G incorporation into human immunodeficiency virus type 1 particles.

  Journal of virology 20041101

• Dual reporter system to dissect cis- and trans-effects influencing the mutation rate in a hypermutating cell line.

  Molecular immunology 20041101

• Identification of an AID-independent pathway for chromosomal translocations between the Igh switch region and Myc.

  Nature immunology 20041101

• Impact of cytidine deaminase activity on intrinsic resistance to cytarabine in carcinoma cells.

  Oncology reports 20041101

• Class switching and Myc translocation: how does DNA break?

  Nature immunology 20041101

• Intrinsic immunity: a front-line defense against viral attack.

  Nature immunology 20041101

• Zebularine: a candidate for epigenetic cancer therapy.

  Drug discovery today 20041101

• Retroviral restriction by APOBEC proteins.

  Nature reviews. Immunology 20041101

• Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy.

  Cancer biology & therapy 20041101

• New classes of HIV inhibitors raise promise for future treatments. HIV experts discuss the most intriguing research.

  AIDS alert 20041101

• Specific packaging of APOBEC3G into HIV-1 virions is mediated by the nucleocapsid domain of the gag polyprotein precursor.

  Virology 20041025

• The in vitro and in vivo effects of re-expressing methylated von Hippel-Lindau tumor suppressor gene in clear cell renal carcinoma with 5-aza-2'-deoxycytidine.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20041015

• Use of chelating ligands to tune the reactive site of half-sandwich ruthenium(II)-arene anticancer complexes.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20041011

• Gene structure and expression of the mouse APOBEC-1 complementation factor: multiple transcriptional initiation sites and a spliced variant with a premature stop translation codon.

  Biochimica et biophysica acta 20041005

• Synthesis of enantiomerically pure D-FDOC, an anti-HIV agent.

  Bioorganic & medicinal chemistry letters 20041004

• Characterization of three novel members of the Arabidopsis thaliana equilibrative nucleoside transporter (ENT) family.

  The Biochemical journal 20041001

• A crucial role of uridine/cytidine kinase 2 in antitumor activity of 3'-ethynyl nucleosides.

  Drug metabolism and disposition: the biological fate of chemicals 20041001

• Transcriptional regulation of APOBEC3G, a cytidine deaminase that hypermutates human immunodeficiency virus.

  The Journal of biological chemistry 20041001

• Loss of CD154 impairs the Th2 extrafollicular plasma cell response but not early T cell proliferation and interleukin-4 induction.

  Immunology 20041001

• CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10.

  Journal of immunology (Baltimore, Md. : 1950) 20041001

• The role of activation-induced cytidine deaminase in antibody diversification, immunodeficiency, and B-cell malignancies.

  The Journal of allergy and clinical immunology 20041001

• Apobec-1 protects intestine from radiation injury through posttranscriptional regulation of cyclooxygenase-2 expression.

  Gastroenterology 20041001

• Inflammation activates Apobec-1 and stabilizes multiple anti-apoptotic mRNAs.

  Gastroenterology 20041001

• CDP-choline increases plasma ACTH and potentiates the stimulated release of GH, TSH and LH: the cholinergic involvement.

  Fundamental & clinical pharmacology 20041001

• Regulation of equilibrative nucleoside uptake by protein kinase inhibitors.

  Nucleosides, nucleotides & nucleic acids 20041001

• Increased cytotoxicity of 2',2'-difluoro-2'-deoxycytidine in human leukemic cell-lines after a preincubation with cyclopentenyl cytosine.

  Nucleosides, nucleotides & nucleic acids 20041001

• Synthesis and polymerase incorporation of 5'-amino-2',5'-dideoxy-5'-N-triphosphate nucleotides.

  Current protocols in nucleic acid chemistry 20041001

• Synthesis, physicochemical and biochemical studies of 1',2'-oxetane constrained adenosine and guanosine modified oligonucleotides, and their comparison with those of the corresponding cytidine and thymidine analogues.

  Journal of the American Chemical Society 20040922

• APOBEC3G versus reverse transcriptase in the generation of HIV-1 drug-resistance mutations.

  AIDS (London, England) 20040903

• Comment on 'Inhibition of hepatitis B virus replication by APOBEC3G'.

  Science (New York, N.Y.) 20040903

• Hepatic secretion of small lipoprotein particles in apobec-1-/- mice is regulated by the LDL receptor.

  Journal of lipid research 20040901

• Role of Id proteins in B lymphocyte activation: new insights from knockout mouse studies.

  Journal of molecular medicine (Berlin, Germany) 20040901

• Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G.

  PLoS biology 20040901

• Optimization of apolipoprotein B mRNA editing by APOBEC1 apoenzyme and the role of its auxiliary factor, ACF.

  RNA (New York, N.Y.) 20040901

• Tissue-specific modification of gld-2 mRNA in C. elegans: likely C-to-U editing.

  RNA (New York, N.Y.) 20040901

• RPA tightens AID to DNA...editing.

  Nature immunology 20040901

• Methotrexate and cytarabine inhibit progression of human lymphoma in NOD/SCID mice carrying a mutant dihydrofolate reductase and cytidine deaminase fusion gene.

  Molecular therapy : the journal of the American Society of Gene Therapy 20040901

• Influence of droplet size, capillary-cone distance and selected instrumental parameters for the analysis of noncovalent protein-ligand complexes by nano-electrospray ionization mass spectrometry.

  Journal of mass spectrometry : JMS 20040901

• [Determination of four nucleosides in Banlangen injections using capillary zone electrophoresis].

  Se pu = Chinese journal of chromatography 20040901

• HIV-1 and MLV Gag proteins are sufficient to recruit APOBEC3G into virus-like particles.

  Biochemical and biophysical research communications 20040827

• Replication protein A interacts with AID to promote deamination of somatic hypermutation targets.

  Nature 20040826

• Immunology: aid for AID.

  Nature 20040826

• Crystal structure of Bacillus subtilis guanine deaminase: the first domain-swapped structure in the cytidine deaminase superfamily.

  The Journal of biological chemistry 20040820

• Human apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (APOBEC3G) is incorporated into HIV-1 virions through interactions with viral and nonviral RNAs.

  The Journal of biological chemistry 20040820

• AID is required for c-myc/IgH chromosome translocations in vivo.

  Cell 20040820

• Immunology. UNGstoppable switching.

  Science (New York, N.Y.) 20040820

• Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch.

  Science (New York, N.Y.) 20040820

• Rapid evolution of primate antiviral enzyme APOBEC3G.

  Human molecular genetics 20040815

• Enantioselectivity of ribonucleotide reductase: a first study using stereoisomers of pyrimidine 2'-azido-2'-deoxynucleosides.

  Biochemical pharmacology 20040815

• APOBEC3G is incorporated into virus-like particles by a direct interaction with HIV-1 Gag nucleocapsid protein.

  The Journal of biological chemistry 20040813

• APOBEC3F properties and hypermutation preferences indicate activity against HIV-1 in vivo.

  Current biology : CB 20040810

• Cytidine deamination of retroviral DNA by diverse APOBEC proteins.

  Current biology : CB 20040810

• The interaction between HIV-1 Gag and APOBEC3G.

  The Journal of biological chemistry 20040806

• Recent insights into HIV-1 Vif.

  Current opinion in immunology 20040801

• The development of a continuous isothermal titration calorimetric method for equilibrium studies.

  Analytical biochemistry 20040801

• DNG cytidine: synthesis and binding properties of octameric guanidinium-linked deoxycytidine oligomer.

  Bioorganic & medicinal chemistry 20040801

• Low temperature FTIR spectra and hydrogen bonds in polycrystalline cytidine.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040801

• Precise dosage of an endogenous mutagen in the immune system.

  Cell cycle (Georgetown, Tex.) 20040801

• Antibody class switching: uncoupling S region accessibility from transcription.

  Trends in genetics : TIG 20040801

• Endogenous expression of activation-induced cytidine deaminase in cell line WEHI-231.

  Journal of immunology (Baltimore, Md. : 1950) 20040801

• Production of cytidine 5'-monophospho-N-acetyl-beta-D-neuraminic acid (CMP-sialic acid) using enzymes or whole cells entrapped in calcium pectate-silica-gel beads.

  Biotechnology and applied biochemistry 20040801

• Preferential response of cancer cells to zebularine.

  Cancer cell 20040801

• Evolution of isotype switching.

  Seminars in immunology 20040801

• APOBEC-mediated editing of viral RNA.

  Science (New York, N.Y.) 20040730

• Sequence- and base-specific delivery of nitric oxide to cytidine and 5-methylcytidine leading to efficient deamination.

  Journal of the American Chemical Society 20040728

• Reduced expression of small GTPases and hypermethylation of the folate binding protein gene in cisplatin-resistant cells.

  British journal of cancer 20040719

• Camelized rabbit-derived VH single-domain intrabodies against Vif strongly neutralize HIV-1 infectivity.

  Journal of molecular biology 20040709

• Synthesis of the phosphoramidite derivatives of 2'-deoxy-2'-C-alpha-methylcytidine and 2'-deoxy-2'-C-alpha-hydroxymethylcytidine: analogues for chemical dissection of RNA's 2'-hydroxyl group.

  The Journal of organic chemistry 20040709

• Characterization of a lipid activated CTP:phosphocholine cytidylyltransferase from Drosophila melanogaster.

  Biochimica et biophysica acta 20040705

• Immunoglobulin diversification in DT40: a model for vertebrate DNA damage tolerance.

  DNA repair 20040702

• Uracil in DNA, determined by an improved assay, is increased when deoxynucleosides are added to folate-deficient cultured human lymphocytes.

  Analytical biochemistry 20040701

• Separate domains of AID are required for somatic hypermutation and class-switch recombination.

  Nature immunology 20040701

• Positive interactive radiosensitisation in vitro with the combination of two nucleoside analogues, (E)-2'-deoxy-2'-(fluoromethylene) cytidine and iododeoxyuridine.

  European journal of cancer (Oxford, England : 1990) 20040701

• Bioactivation of capecitabine in human liver: involvement of the cytosolic enzyme on 5'-deoxy-5-fluorocytidine formation.

  Drug metabolism and disposition: the biological fate of chemicals 20040701

• Class-switch recombination: interplay of transcription, DNA deamination and DNA repair.

  Nature reviews. Immunology 20040701

• Retroviruses under editing crossfire: a second member of the human APOBEC3 family is a Vif-blockable innate antiretroviral factor.

  EMBO reports 20040701

• Activation-induced cytidine deaminase initiates immunoglobulin gene conversion and hypermutation by a common intermediate.

  PLoS biology 20040701

• Borate-nucleotide complex formation depends on charge and phosphorylation state.

  Journal of mass spectrometry : JMS 20040701

• The Escherichia coli 3-methyladenine DNA glycosylase AlkA has a remarkably versatile active site.

  The Journal of biological chemistry 20040625

• Activation-induced cytosine deaminase (AID) is actively exported out of the nucleus but retained by the induction of DNA breaks.

  The Journal of biological chemistry 20040618

• Synthesis, structure-activity relationships, and drug resistance of beta-d-3'-fluoro-2',3'-unsaturated nucleosides as anti-HIV Agents.

  Journal of medicinal chemistry 20040617

• Alteration of the copy number and deletion of mitochondrial DNA in human hepatocellular carcinoma.

  British journal of cancer 20040614

• Cloning and expression of the AID gene in the channel catfish.

  Developmental and comparative immunology 20040601

• Activation induced deaminase: the importance of being specific.

  Trends in genetics : TIG 20040601

• Advantages and disadvantages of cytidine deamination.

  Journal of immunology (Baltimore, Md. : 1950) 20040601

• Functional domains of APOBEC3G required for antiviral activity.

  Journal of cellular biochemistry 20040601

• Crystallization and preliminary crystallographic analysis of Bacillus subtilis guanine deaminase.

  Acta crystallographica. Section D, Biological crystallography 20040601

• The viral infectivity factor (Vif) of HIV-1 unveiled.

  Trends in molecular medicine 20040601

• Determination of ribavirin in human serum and plasma by capillary electrophoresis.

  Electrophoresis 20040601

• Abnormalities in peripheral B cell memory of patients with primary Sjögren's syndrome.

  Arthritis and rheumatism 20040601

• AID: how does it aid antibody diversity?

  Immunity 20040601

• Molecular cloning of canine activation-induced cytidine deaminase (AID) cDNA and its expression in normal tissues.

  The Journal of veterinary medical science 20040601

• Structural, kinetic, and mutational studies of the zinc ion environment in tetrameric cytidine deaminase.

  Biochemistry 20040525

• Scientists probe shutting down cancer cells by awakening silenced genes.

  JAMA 20040519

• Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat.

  Blood 20040515

• Microarray analysis of epigenetic silencing of gene expression in the KAS-6/1 multiple myeloma cell line.

  Cancer research 20040515

• Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans.

  Cell 20040514

• A conformational switch controls hepatitis delta virus ribozyme catalysis.

  Nature 20040513

• Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome.

  Nature structural & molecular biology 20040501

• Cutting edge: IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells.

  Journal of immunology (Baltimore, Md. : 1950) 20040501

• Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase.

  Structure (London, England : 1993) 20040501

• Synergistic cytotoxicity and pharmacogenetics of gemcitabine and pemetrexed combination in pancreatic cancer cell lines.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040501

• Nucleotides in sow colostrum and milk at different stages of lactation.

  Journal of animal science 20040501

• A single amino acid determinant governs the species-specific sensitivity of APOBEC3G to Vif action.

  The Journal of biological chemistry 20040409

• Capecitabine in hormone-resistant metastatic prostatic carcinoma - a phase II trial.

  British journal of cancer 20040405

• Mantle cell lymphoma with t(11;14) and unmutated or mutated VH genes expresses AID and undergoes isotype switch events.

  Blood 20040401

• High expression of activation-induced cytidine deaminase (AID) mRNA is associated with unmutated IGVH gene status and unfavourable cytogenetic aberrations in patients with chronic lymphocytic leukaemia.

  Leukemia 20040401

• Activation-induced cytidine deaminase expression in follicular lymphoma: association between AID expression and ongoing mutation in FL.

  Leukemia 20040401

• The regulation of somatic hypermutation.

  Current opinion in immunology 20040401

• Recombinogenic phenotype of human activation-induced cytosine deaminase.

  Journal of immunology (Baltimore, Md. : 1950) 20040401

• A quantitative appraisal of the ambivalent metal ion binding properties of cytidine in aqueous solution and an estimation of the anti-syn energy barrier of cytidine derivatives.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20040401

• The Saccharomyces cerevisiae TAN1 gene is required for N4-acetylcytidine formation in tRNA.

  RNA (New York, N.Y.) 20040401

• Rectification of age-related impairment in Ig gene hypermutation during a memory response.

  International immunology 20040401

• Staggered AID-dependent DNA double strand breaks are the predominant DNA lesions targeted to S mu in Ig class switch recombination.

  International immunology 20040401

• Synthesis of selenium-derivatized cytidine and oligonucleotides for X-ray crystallography using MAD.

  Organic letters 20040401

• The hyperthermophilic origin of life revisited.

  Biochemical Society transactions 20040401

• HIV-1 Vif versus APOBEC3G: newly appreciated warriors in the ancient battle between virus and host.

  Trends in microbiology 20040401

• Enzymatic conversion of cytidine to lysidine in anticodon of bacterial isoleucyl-tRNA--an alternative way of RNA editing.

  Trends in biochemical sciences 20040401

• Inhibitory effect of pyrimidine and purine nucleotides on the multiplication of Babesia gibsoni: possible cause of low parasitemia and simultaneous reticulocytosis in canine babesiosis.

  The Journal of veterinary medical science 20040401

• A single nucleotide polymorphism map of the mitochondrial genome of the parasitic nematode Cooperia oncophora.

  Parasitology 20040401

• Gemcitabine and docetaxel in metastatic and neoadjuvant treatment of breast cancer.

  Seminars in oncology 20040401

• Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo.

  Journal of molecular biology 20040326

• Mechanics of DNA flexibility visualized by selective 2'-amine acylation at nucleotide bulges.

  Journal of molecular biology 20040326

• Inhibition of hepatitis B virus replication by APOBEC3G.

  Science (New York, N.Y.) 20040319

• Cutting edge: DGYW/WRCH is a better predictor of mutability at G:C bases in Ig hypermutation than the widely accepted RGYW/WRCY motif and probably reflects a two-step activation-induced cytidine deaminase-triggered process.

  Journal of immunology (Baltimore, Md. : 1950) 20040315

• Adenosine-dependent assembly of aptazyme-functionalized gold nanoparticles and its application as a colorimetric biosensor.

  Analytical chemistry 20040315

• Xylocydine, a novel inhibitor of cyclin-dependent kinases, prevents the tumor necrosis factor-related apoptosis-inducing ligand-induced apoptotic cell death of SK-HEP-1 cells.

  The Journal of pharmacology and experimental therapeutics 20040301

• Induction of activation-induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkappaB.

  International immunology 20040301

• Non-redundancy of cytidine deaminases in class switch recombination.

  European journal of immunology 20040301

• Mapping of a functional recombination motif that defines isotype specificity for mu-->gamma3 switch recombination implicates NF-kappaB p50 as the isotype-specific switching factor.

  The Journal of experimental medicine 20040301

• Therapeutic applications of citicoline for stroke and cognitive dysfunction in the elderly: a review of the literature.

  Alternative medicine review : a journal of clinical therapeutic 20040301

• Reactions of N,N-bis(2-chloroethyl)-p-aminophenylbutyric acid (chlorambucil) with 2'-deoxycytidine, 2'-deoxy-5-methylcytidine, and thymidine.

  Chemical research in toxicology 20040301

• Analysis of strand biased 'G'.C hypermutation in human immunoglobulin V(lambda) gene segments suggests that both DNA strands are targets for deamination by activation-induced cytidine deaminase.

  Molecular immunology 20040301

• Vif overcomes the innate antiviral activity of APOBEC3G by promoting its degradation in the ubiquitin-proteasome pathway.

  The Journal of biological chemistry 20040227

• Mode of binding of camptothecins to double helix oligonucleotides.

  Organic & biomolecular chemistry 20040221

• DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine.

  The Journal of biological chemistry 20040220

• Multilamellar liposomes formed by phosphatidyl nucleosides: an NMR-HR-MAS characterization.

  Langmuir : the ACS journal of surfaces and colloids 20040217

• Reduced Ig class switch in aged mice correlates with decreased E47 and activation-induced cytidine deaminase.

  Journal of immunology (Baltimore, Md. : 1950) 20040215

• Crystallographic studies on structural features that determine the enzymatic specificity and potency of human angiogenin: Thr44, Thr80, and residues 38-41.

  Biochemistry 20040210

• Fluorescence properties of 2-aminopurine-cytidine-7-deazaguanine (5'-ApCdzG-3') trimer in B- and Z-DNA.

  Chemical communications (Cambridge, England) 20040207

• Mutagenicity of the cytidine analog zebularine in Escherichia coli.

  DNA repair 20040203

• Centrally injected CDP-choline increases plasma vasopressin levels by central cholinergic activation.

  Fundamental & clinical pharmacology 20040201

• Self-assembling of cytosine nucleoside into triply-bound dimers in acid media. A comprehensive evaluation of proton-bound pyrimidine nucleosides by electrospray tandem mass spectrometry, X-rays diffractometry, and theoretical calculations.

  Journal of the American Society for Mass Spectrometry 20040201

• Immunoglobulin gene conversion in chicken DT40 cells largely proceeds through an abasic site intermediate generated by excision of the uracil produced by AID-mediated deoxycytidine deamination.

  European journal of immunology 20040201

• Antitumor activity of sugar-modified cytosine nucleosides.

  Cancer science 20040201

• T cell-independent somatic hypermutation in murine B cells with an immature phenotype.

  Immunity 20040201

• PEG-Ara-C conjugates for controlled release.

  European journal of medicinal chemistry 20040201

• [HIV-1, a very Vif virus].

  Medecine sciences : M/S 20040201

• Glycine 154 of the equilibrative nucleoside transporter, hENT1, is important for nucleoside transport and for conferring sensitivity to the inhibitors nitrobenzylthioinosine, dipyridamole, and dilazep.

  Biochemical pharmacology 20040201

• Differential effect of IL-4 and IL-13 on the expression of recombination-activating genes in mature B cells from human peripheral blood.

  Cellular immunology 20040201

• Does AID aid AIDS?

  Immunology letters 20040130

• Effects of fluorine substitution of cytosine analogues on the binding affinity to HIV-1 reverse transcriptase.

  Bioorganic & medicinal chemistry letters 20040119

• The role of cytidine deaminase and GATA1 mutations in the increased cytosine arabinoside sensitivity of Down syndrome myeloblasts and leukemia cell lines.

  Cancer research 20040115

• Protonation effect on drug affinity.

  European journal of pharmacology 20040112

• DNA-cytosine deaminases: from antibody maturation to antiviral defense.

  DNA repair 20040105

• Identification of novel alternative splice variants of APOBEC-1 complementation factor with different capacities to support apolipoprotein B mRNA editing.

  The Journal of biological chemistry 20040102

• Hepatic secretion of apoB-100 is impaired in hypobetalipoproteinemic mice with an apoB-38.9-specifying allele.

  Journal of lipid research 20040101

• Fourier transform infrared spectroscopy study on order-disorder transition in Langmuir-Blodgett films of 7-(2-octadecyloxycarbonylethyl)guanine before and after recognition to cytidine.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040101

• Synthesis, stability, and protonation studies of a self-complementary dodecamer containing the modified nucleoside 2'-deoxyzebularine.

  Biopolymers 20040101

• Human primary immunodeficiency diseases: a perspective.

  Nature immunology 20040101

• From restriction factors to restriction enzymes.

  Reviews in medical virology 20040101

• JAMM: a metalloprotease-like zinc site in the proteasome and signalosome.

  PLoS biology 20040101

• Insulin receptor activation and down-regulation by cationic lipid transfection reagents.

  BMC cell biology 20040101

• Gemcitabine and taxanes as a new standard of care in breast cancer.

  Clinical breast cancer 20040101

• Linkage and association of childhood asthma with the chromosome 12 genes.

  Journal of human genetics 20040101

• Clinical, immunologic and genetic analysis of 29 patients with autosomal recessive hyper-IgM syndrome due to Activation-Induced Cytidine Deaminase deficiency.

  Clinical immunology (Orlando, Fla.) 20040101

• Transcription-coupled mutagenesis by the DNA deaminase AID.

  Genome biology 20040101

• Expression of activation-induced cytidine deaminase (AID) in Burkitt lymphoma cells: rare AID-negative cell lines with the unmutated rearranged VH gene.

  Leukemia & lymphoma 20040101

• Action of troxacitabine on cells transduced with human cytidine deaminase cDNA.

  Cancer investigation 20040101

• Bioinformatic identification of novel regulatory DNA sequence motifs in Streptomyces coelicolor.

  BMC microbiology 20040101

• Inhibition of severe acute respiratory syndrome-associated coronavirus (SARSCoV) by calpain inhibitors and beta-D-N4-hydroxycytidine.

  Antiviral chemistry & chemotherapy 20040101

• Synthesis and fluorescence studies of multiple labeled oligonucleotides containing dansyl fluorophore covalently attached at 2'-terminus of cytidine via carbamate linkage.

  Bioconjugate chemistry 20040101

• Resistance to gemcitabine in a human follicular lymphoma cell line is due to partial deletion of the deoxycytidine kinase gene.

  BMC pharmacology 20040101

• Control of pyrimidine biosynthesis in 'Pseudomonas alkanolytica' ATCC 21034.

  Journal of basic microbiology 20040101

• New insights into the role of Vif in HIV-1 replication.

  AIDS reviews 20040101

• Early steps of retrovirus replicative cycle.

  Retrovirology 20040101

• Cloning and functional characterisation of avian transcription factor E2A.

  BMC immunology 20040101

• The synthesis of [([beta-D-ribofuranosyloxy)methyl]nucleosides.

  Nucleosides, nucleotides & nucleic acids 20040101

• Involvement of p53 in 1-beta-D-arabinofuranosylcytosine-induced rat fetal brain lesions.

  Neurotoxicology and teratology 20040101

• Chemically induced DNA hypomethylation in breast carcinoma cells detected by the amplification of intermethylated sites.

  Breast cancer research : BCR 20040101

• Treatment of HCC with pravastatin, octreotide, or gemcitabine--a critical evaluation.

  Hepato-gastroenterology 20040101

• Retroviruses 2004: review of the 2004 Cold Spring Harbor Retroviruses Conference.

  Retrovirology 20040101

• Production of infectious human immunodeficiency virus type 1 does not require depletion of APOBEC3G from virus-producing cells.

  Retrovirology 20040101

• Simple statistical models predict C-to-U edited sites in plant mitochondrial RNA.

  BMC bioinformatics 20040101

• HIV-1 Vif and APOBEC3G: multiple roads to one goal.

  Retrovirology 20040101

• Few amino acid positions in rpoB are associated with most of the rifampin resistance in Mycobacterium tuberculosis.

  BMC bioinformatics 20040101

• Preliminary investigation of electrodynamic charged droplet processing to couple capillary liquid chromatography with matrix-assisted laser desorption/ionization mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20040101

• Genetic control of retrovirus susceptibility in mammalian cells.

  Annual review of genetics 20040101

• New nucleoside analogs in the treatment of solid tumors.

  Acta poloniae pharmaceutica 20040101

• Over expression of the selectable marker blasticidin S deaminase gene is toxic to human keratinocytes and murine BALB/MK cells.

  BMC biotechnology 20040101

• Why genomics is more than genomes.

  Genome biology 20040101

• Somatic hypermutation: a mutational panacea.

  Advances in protein chemistry 20040101

• Thiosugars. XII. Synthesis of new 3'-O-substituted 2',5'-anhydro-2'-thio-alpha-D-pentofuranosyl nucleoside analogues.

  Nucleosides, nucleotides & nucleic acids 20040101

• Synthesis and properties of 5-pyrrolyl-cytidine and uridine derivatives.

  Nucleic acids symposium series (2004) 20040101

• Selective nitrosyl group transfer reaction to cytidine using oligonucleotides bearing S-nitrosothioguanosine.

  Nucleic acids symposium series (2004) 20040101

• Synthesis and evaluation of the functional oligonucleotides-PEG conjugates.

  Nucleic acids symposium series (2004) 20040101

• Involvement of a chaperone regulator, Bcl2-associated athanogene-4, in apolipoprotein B mRNA editing.

  The Journal of biological chemistry 20031226

• Transcription-coupled events associating with immunoglobulin switch region chromatin.

  Science (New York, N.Y.) 20031219

• Quantification of uridine 5'-diphosphate (UDP)-glucose by high-performance liquid chromatography and its application to a nonradioactive assay for nucleoside diphosphate kinase using UDP-glucose pyrophosphorylase as a coupling enzyme.

  Analytical biochemistry 20031215

• Reduced switching in SCID B cells is associated with altered somatic mutation of recombined S regions.

  Journal of immunology (Baltimore, Md. : 1950) 20031215

• Combination chemotherapy in advanced gastrointestinal cancers: ex vivo sensitivity to gemcitabine and mitomycin C.

  British journal of cancer 20031215

• Hyper-immunoglobulin-M syndromes caused by an intrinsic B cell defect.

  Current opinion in allergy and clinical immunology 20031201

• Glycosyltransferase assays utilizing N-acetyllactosamine acceptor immobilized on a cellulose membrane.

  Analytical biochemistry 20031201

• Domain organization of activation-induced cytidine deaminase.

  Nature immunology 20031201

• Review article: chemotherapy for pancreatic cancer.

  Alimentary pharmacology & therapeutics 20031201

• Hyper-IgM syndrome with CHARGE association.

  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20031201

• Serum from dogs Infected with Babesia gibsoni inhibits maturation of reticulocytes and erythrocyte 5'-nucleotidase activity in vitro.

  The Journal of veterinary medical science 20031201

• Synthesis and anti-cancer activity of some novel 5-azacytosine nucleosides.

  Nucleosides, nucleotides & nucleic acids 20031201

• Potent inhibition of HhaI DNA methylase by the aglycon of 2-(1H)-pyrimidinone riboside (zebularine) at the GCGC recognition domain.

  Annals of the New York Academy of Sciences 20031201

• Functional properties of subunit interactions in human cytidine deaminase.

  Protein engineering 20031201

• [Detection and identification of emergence of HBV YMDD motif mutation during lamivudine treatment by hybridization to an oligonucleotide array].

  Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20031201

• In vitro RNA editing in pea mitochondria requires NTP or dNTP, suggesting involvement of an RNA helicase.

  The Journal of biological chemistry 20031128

• Nucleic acid structures and enzymes in the immunoglobulin class switch recombination mechanism.

  DNA repair 20031121

• Oligonucleotide duplexes containing N8-glycosylated 8-aza-7-deazaguanine and self-assembly of 8-aza-7-deazapurines on the nucleoside and the oligomeric level.

  Organic & biomolecular chemistry 20031121

• A phase II trial of capecitabine (Xeloda) in recurrent ovarian cancer.

  British journal of cancer 20031117

• Neuroprotective effect of citicoline in 6-hydroxydopamine-lesioned rats and in 6-hydroxydopamine-treated SH-SY5Y human neuroblastoma cells.

  Journal of the neurological sciences 20031115

• EBV-encoded latent membrane protein 1 cooperates with BAFF/BLyS and APRIL to induce T cell-independent Ig heavy chain class switching.

  Journal of immunology (Baltimore, Md. : 1950) 20031115

• Local somatic hypermutation and class switch recombination in the nasal mucosa of allergic rhinitis patients.

  Journal of immunology (Baltimore, Md. : 1950) 20031115

• The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G.

  Current biology : CB 20031111

• The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity.

  The Journal of biological chemistry 20031107

• Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex.

  Science (New York, N.Y.) 20031107

• Activation-induced cytidine deaminase in chronic lymphocytic leukemia B cells: expression as multiple forms in a dynamic, variably sized fraction of the clone.

  Blood 20031101

• The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif.

  Nature medicine 20031101

• HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation.

  Nature medicine 20031101

• [Correlation between activation-induced cytidine deaminase gene polymorphism and atopic asthma and plasma IgE in adult].

  Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20031101

• A role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage.

  Oncogene 20031020

• Selective fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene by nucleotides.

  Organic letters 20031016

• Intestinal lipoprotein assembly in apobec-1-/- mice reveals subtle alterations in triglyceride secretion coupled with a shift to larger lipoproteins.

  American journal of physiology. Gastrointestinal and liver physiology 20031001

• Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination.

  Nature immunology 20031001

• Epimer interconversion, isomerization, and hydrolysis of tetrahydrouridine: implications for cytidine deaminase inhibition.

  Journal of pharmaceutical sciences 20031001

• Non-covalent and coordination interactions in Cu(II) systems with uridine, uridine 5'-monophosphate and triamine or tetramine as biogenic amine analogues in aqueous solutions.

  Journal of inorganic biochemistry 20031001

• Mutations in AID and UNG extend the function of AID.

  Nature immunology 20031001

• A functional analysis of the spacer of V(D)J recombination signal sequences.

  PLoS biology 20031001

• Death and the retrovirus.

  Trends in molecular medicine 20031001

• Adenovirus type 5 E1A sensitizes hepatocellular carcinoma cells to gemcitabine.

  Cancer research 20031001

• Hyper-IgM syndrome with putative dominant negative mutation in activation-induced cytidine deaminase.

  The Journal of allergy and clinical immunology 20031001

• HIV-1 Vif: counteracting innate antiretroviral defenses.

  Molecular therapy : the journal of the American Society of Gene Therapy 20031001

• Mutations in eukaryotic release factors 1 and 3 act as general nonsense suppressors in Drosophila.

  Genetics 20031001

• Phospholipase A2, hydroxyl radicals, and lipid peroxidation in transient cerebral ischemia.

  Antioxidants & redox signaling 20031001

• Inhibitors of DNA methylation in the treatment of hematological malignancies and MDS.

  Clinical immunology (Orlando, Fla.) 20031001

• AID mutant analyses indicate requirement for class-switch-specific cofactors.

  Nature immunology 20030901

• EPR and ENDOR study of crystalline cytosine x HCl doped with 5-methylcytosine. Radiation-induced radical formation and hole transfer.

  Radiation research 20030901

• The block in immunoglobulin class switch recombination caused by activation-induced cytidine deaminase deficiency occurs prior to the generation of DNA double strand breaks in switch mu region.

  Journal of immunology (Baltimore, Md. : 1950) 20030901

• Mutagenesis by AID, a molecule critical to immunoglobulin hypermutation, is not caused by an alteration of the precursor nucleotide pool.

  Molecular immunology 20030901

• An insight into the phenomena involved in a multiple-function stationary phase for the capillary electrochromatographic separation of 2'-, 3'-, and 5'-monophosphorylated nucleoside isomers.

  Electrophoresis 20030901

• cis-1,4-diaminocyclohexane-Pt(II) and -(IV) adducts with DNA bases and nucleosides.

  Journal of inorganic biochemistry 20030901

• HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability.

  Molecular cell 20030901

• 5-Chlorouracil, a marker of DNA damage from hypochlorous acid during inflammation. A gas chromatography-mass spectrometry assay.

  The Journal of biological chemistry 20030829

• Alpha-phosphono lactone analogues of cytidine and cytosine arabinoside diphosphates: synthesis via ring closing metathesis.

  The Journal of organic chemistry 20030822

• Synthesis of the phosphoramidite derivative of 2'-deoxy-2'-C-beta-methylcytidine.

  The Journal of organic chemistry 20030822

• B cells pay a price.

  Oncogene 20030821

• Virology. Weapons of mutational destruction.

  Science (New York, N.Y.) 20030815

• Synthesis of 5'-amino-5'-phosphonate analogues of pyrimidine nucleoside monophosphates.

  The Journal of organic chemistry 20030808

• Death by deamination: a novel host restriction system for HIV-1.

  Cell 20030808

• Citicoline decreases phospholipase A2 stimulation and hydroxyl radical generation in transient cerebral ischemia.

  Journal of neuroscience research 20030801

• Crystallization and preliminary X-ray analysis of human uridine-cytidine kinase 2.

  Acta crystallographica. Section D, Biological crystallography 20030801

• The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay.

  The EMBO journal 20030801

• Activation-induced cytidine deaminase: a dual role in class-switch recombination and somatic hypermutation.

  European journal of immunology 20030801

• MS2Assign, automated assignment and nomenclature of tandem mass spectra of chemically crosslinked peptides.

  Journal of the American Society for Mass Spectrometry 20030801

• Lack of association between the 7888 C/T polymorphism in the AID gene and atopy in a Spanish population.

  The Journal of allergy and clinical immunology 20030801

• The 1.14 A crystal structure of yeast cytosine deaminase: evolution of nucleotide salvage enzymes and implications for genetic chemotherapy.

  Structure (London, England : 1993) 20030801

• Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumors.

  Cancer research 20030801

• Functional analysis of human memory B-cell subpopulations: IgD+CD27+ B cells are crucial in secondary immune response by producing high affinity IgM.

  Clinical immunology (Orlando, Fla.) 20030801

• C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion.

  Molecular cell 20030801

• Identification and characterisation of high affinity nucleoside and nucleobase transporters in Toxoplasma gondii.

  International journal for parasitology 20030730

• 2'-chloro-2',3'-dideoxy-3'-fluoro-d-ribonucleosides: synthesis, stereospecificity, some chemical transformations, and conformational analysis.

  The Journal of organic chemistry 20030725

• Novel guanosine-cytidine dinucleoside that self-assembles into a trimeric supramolecule.

  Organic letters 20030724

• l-2',3'-Didehydro-2',3'-dideoxy-3'-fluoronucleosides: synthesis, anti-HIV activity, chemical and enzymatic stability, and mechanism of resistance.

  Journal of medicinal chemistry 20030717

• Expression of activation-induced cytidine deaminase is confined to B-cell non-Hodgkin's lymphomas of germinal-center phenotype.

  Cancer research 20030715

• Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif.

  Cell 20030711

• Differential translation of TOP mRNAs in rapamycin-treated human B lymphocytes.

  Biochimica et biophysica acta 20030709

• The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA.

  Nature 20030703

• Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts.

  Nature 20030703

• Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation.

  Nature 20030703

• Good to CU.

  Nature 20030703

• What role for AID: mutator, or assembler of the immunoglobulin mutasome?

  Nature immunology 20030701

• DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses.

  Nature immunology 20030701

• Novel antibody switching defects in human patients.

  The Journal of clinical investigation 20030701

• Hyper-IgM syndrome type 4 with a B lymphocyte-intrinsic selective deficiency in Ig class-switch recombination.

  The Journal of clinical investigation 20030701

• Photochemical cross-linking of Escherichia coli Fpg protein to DNA duplexes containing phenyl(trifluoromethyl)diazirine groups.

  European journal of biochemistry 20030701

• Hepatic gene expression profiling reveals perturbed calcium signaling in a mouse model lacking both LDL receptor and Apobec1 genes.

  Atherosclerosis 20030701

• Lipoprotein subclass profiles of hyperlipidemic diabetic mice measured by nuclear magnetic resonance spectroscopy.

  Metabolism: clinical and experimental 20030701

• Prolactin, cortisol, and insulin regulation of nucleoside uptake into mouse mammary gland explants.

  Experimental biology and medicine (Maywood, N.J.) 20030701

• Immunoglobulin somatic hypermutation: double-strand DNA breaks, AID and error-prone DNA repair.

  Journal of clinical immunology 20030701

• Design and synthesis of phosphonoacetic acid (PPA) ester and amide bioisosters of ribofuranosylnucleoside diphosphates as potential ribonucleotide reductase inhibitors and evaluation of their enzyme inhibitory, cytostatic and antiviral activity.

  Antiviral chemistry & chemotherapy 20030701

• Stable transgene expression and random gene silencing in wheat.

  Plant biotechnology journal 20030701

• Deoxyribonucleoside 2'- or 3'-mixed disulfides: prodrugs to target ribonucleotide reductase and/or to inhibit HIV reverse transcription.

  Journal of medicinal chemistry 20030619

• Synthesis and characterization of platinum diimine bis(acetylide) complexes containing easily derivatizable aryl acetylide ligands.

  Inorganic chemistry 20030616

• High expression of activation-induced cytidine deaminase (AID) and splice variants is a distinctive feature of poor-prognosis chronic lymphocytic leukemia.

  Blood 20030615

• DNA deamination mediates innate immunity to retroviral infection.

  Cell 20030613

• Synthesis of cytidine ribonucleotides by stepwise assembly of the heterocycle on a sugar phosphate.

  Chembiochem : a European journal of chemical biology 20030606

• E-proteins directly regulate expression of activation-induced deaminase in mature B cells.

  Nature immunology 20030601

• Human cytomegalovirus requires cellular deoxycytidylate deaminase for replication in quiescent cells.

  The Journal of general virology 20030601

• Dietary cytidine (5')-diphosphocholine supplementation protects against development of memory deficits in aging rats.

  Progress in neuro-psychopharmacology & biological psychiatry 20030601

• Functional characterization of a H+/nucleoside co-transporter (CaCNT) from Candida albicans, a fungal member of the concentrative nucleoside transporter (CNT) family of membrane proteins.

  Yeast (Chichester, England) 20030601

• Rapid determination of rat plasma uridine levels by HPLC-ESI-MS utilizing the Captiva plates for sample preparation.

  Biomedical chromatography : BMC 20030601

• [Expression of cytidine deaminase mRNA in bone marrow cells from patients with acute leukemia].

  Zhongguo shi yan xue ye xue za zhi 20030601

• Action spectra for UV-light induced RNA-RNA crosslinking in 16S ribosomal RNA in the ribosome.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20030601

• Phospholipids from Bombycis corpus and their neurotrophic effects.

  Archives of pharmacal research 20030601

• Protonation of deoxycytidine residues in dC4 tetraloops: UV spectrophotometric study of dC10 and d(A14C4T14).

  Biophysical chemistry 20030601

• In vitro deamination of cytosine to uracil in single-stranded DNA by apolipoprotein B editing complex catalytic subunit 1 (APOBEC1).

  The Journal of biological chemistry 20030530

• Sheared-type G(anti).C(syn) base-pair: a unique d(GXC) loop closure motif.

  Journal of molecular biology 20030530

• Synthesis of the cyclic and acyclic acetal derivatives of 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine, a potent antitumor nucleoside. Design of prodrugs to be selectively activated in tumor tissues via the bio-reduction-hydrolysis mechanism.

  Bioorganic & medicinal chemistry 20030529

• Crystal structure of yeast cytosine deaminase. Insights into enzyme mechanism and evolution.

  The Journal of biological chemistry 20030523

• Hypermutation of HIV-1 DNA in the absence of the Vif protein.

  Science (New York, N.Y.) 20030516

• Chronic lymphocytic leukemia B cells expressing AID display dissociation between class switch recombination and somatic hypermutation.

  Blood 20030515

• Drug reactivates genes to inhibit cancer.

  Drug discovery today 20030515

• A novel cytidine deaminase AIDs in the delivery of error-prone polymerases to immunoglobulin genes.

  DNA repair 20030513

• Requirement of dimerization for RNA editing activity of adenosine deaminases acting on RNA.

  The Journal of biological chemistry 20030509

• Stimulation of CDP-choline synthesis by uridine or cytidine in PC12 rat pheochromocytoma cells.

  Brain research 20030509

• Intravenously injected CDP-choline increases blood pressure and reverses hypotension in haemorrhagic shock: effect is mediated by central cholinergic activation.

  European journal of pharmacology 20030509

• Identification of lysine 122 and arginine 196 as important functional residues of rat CTP:phosphocholine cytidylyltransferase alpha.

  Biochemistry 20030506

• The first radical method for the introduction of an ethynyl group using a silicon tether and its application to the synthesis of 2'-deoxy-2'-C-ethynylnucleosides.

  The Journal of organic chemistry 20030502

• Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas.

  Blood 20030501

• Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand.

  Nature immunology 20030501

• RNA AIDS DNA.

  Nature immunology 20030501

• Canonical 3'-deoxyribonucleotides as a chain terminator for HCV NS5B RNA-dependent RNA polymerase.

  Antiviral research 20030501

• Detection of scalar couplings involving 2'-hydroxyl protons across hydrogen bonds in a frameshifting mRNA pseudoknot.

  Journal of the American Chemical Society 20030423

• Transcription-targeted DNA deamination by the AID antibody diversification enzyme.

  Nature 20030417

• Ionization of a critical adenosine residue in the neurospora Varkud Satellite ribozyme active site.

  Biochemistry 20030415

• Role of protein-protein bridging interactions on cooperative assembly of DNA-bound CRP-CytR-CRP complex and regulation of the Escherichia coli CytR regulon.

  Biochemistry 20030408

• Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs.

  The Journal of biological chemistry 20030404

• Class-switch recombination: after the dawn of AID.

  Current opinion in immunology 20030401

• 5-Methyl-6-aza-2'-deoxyisocytidine.

  Acta crystallographica. Section C, Crystal structure communications 20030401

• Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business.

  Trends in genetics : TIG 20030401

• Postnatal bone marrow stromal cells elicit a potent VEGF-dependent neoangiogenic response in vivo.

  Gene therapy 20030401

• Hydrolytic nucleoside and nucleotide deamination, and genetic instability: a possible link between RNA-editing enzymes and cancer?

  Trends in molecular medicine 20030401

• Activation-induced cytidine deaminase links class switch recombination and somatic hypermutation.

  Annals of the New York Academy of Sciences 20030401

• Photophysical properties of 5-methylcytidine.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20030401

• Role of platelet-derived endothelial cell growth factor/thymidine phosphorylase in fluoropyrimidine sensitivity.

  British journal of cancer 20030324

• Molecular recognition of 7-(2-octadecyloxycarbonylethyl)guanine to cytidine at the air/water interface and LB film studied by Fourier transform infrared spectroscopy.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030315

• Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine.

  Bioorganic & medicinal chemistry letters 20030310

• Penetration of capecitabine and its metabolites into malignant and healthy tissues of patients with advanced breast cancer.

  British journal of cancer 20030310

• Inhibition of DNA methylation and reactivation of silenced genes by zebularine.

  Journal of the National Cancer Institute 20030305

• Thermodynamic, kinetic and structural studies on the mixed ligand complexes of palladium(II) with tridentate and monodentate ligands.

  Journal of inorganic biochemistry 20030301

• X-linked amelogenesis imperfecta may result from decreased formation of tyrosine rich amelogenin peptide (TRAP).

  Archives of oral biology 20030301

• Type two hyper-IgM syndrome caused by mutation in activation-induced cytidine deaminase.

  Journal of medical and dental sciences 20030301

• Determination of thalidomide in transport buffer for Caco-2 cell monolayers by high-performance liquid chromatography with ultraviolet detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030225

• Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia.

  Blood 20030215

• Human activation-induced cytidine deaminase is induced by IL-4 and negatively regulated by CD45: implication of CD45 as a Janus kinase phosphatase in antibody diversification.

  Journal of immunology (Baltimore, Md. : 1950) 20030215

• Determination of 3'-C-ethynylcytidine in human plasma and urine by liquid chromatographic-electrospray ionization tandem mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20030205

• Thyroid hormone regulates hepatic triglyceride mobilization and apolipoprotein B messenger ribonucleic Acid editing in a murine model of congenital hypothyroidism.

  Endocrinology 20030201

• Effects of cytidine 5'-diphosphocholine on plasma homocysteine levels in rat.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030201

• Rabbit liver dCMP phosphohydrolase: a pyrimidine 5'-nucleotidase I-like enzyme in non-erythrocytic cells.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030201

• Relation between reticulocyte count and characteristics of erythrocyte 5'-nucleotidase in dogs, cats, cattle and humans.

  The Journal of veterinary medical science 20030201

• Singlet excited-state lifetimes of cytosine derivatives measured by femtosecond transient absorption.

  Photochemistry and photobiology 20030201

• [Two years after, activation-induced cytidine deaminase has not revealed all of its secrets].

  Medecine sciences : M/S 20030201

• 6-aza-2'-deoxyisocytidine: synthesis, properties of oligonucleotides, and base-pair stability adjustment of DNA with parallel strand orientation.

  The Journal of organic chemistry 20030124

• The reactions of cytidine and 2'-deoxycytidine with SO4.- revisited. Pulse radiolysis and product studies.

  Organic & biomolecular chemistry 20030121

• Cyclopentenyl cytosine primes SK-N-BE(2)c neuroblastoma cells for cytarabine toxicity.

  International journal of cancer 20030120

• Regulatable liver expression of the rabbit apolipoprotein B mRNA-editing enzyme catalytic polypeptide 1 (APOBEC-1) in mice lacking endogenous APOBEC-1 leads to aberrant hyperediting.

  The Biochemical journal 20030115

• Copper(II) complexes with uridine, uridine 5'-monophosphate, spermidine, or spermine in aqueous solution.

  Journal of inorganic biochemistry 20030115

• Highly selective binding of organometallic ruthenium ethylenediamine complexes to nucleic acids: novel recognition mechanisms.

  Journal of the American Chemical Society 20030108

• Antisense oligonuclotides with oxetane-constrained cytidine enhance heteroduplex stability, and elicit satisfactory RNase H response as well as showing improved resistance to both exo and endonucleases.

  Organic & biomolecular chemistry 20030107

• Antiviral activity of cyclopentenyl nucleosides against orthopox viruses (Smallpox, monkeypox and cowpox).

  Bioorganic & medicinal chemistry letters 20030106

• The salivary purine nucleosidase of the mosquito, Aedes aegypti.

  Insect biochemistry and molecular biology 20030101

• Uncommon cytidine-homopolymer dimorphism in 5'-UTR of the human otoferlin gene.

  International journal of molecular medicine 20030101

• Ribonucleoside analogue that blocks replication of bovine viral diarrhea and hepatitis C viruses in culture.

  Antimicrobial agents and chemotherapy 20030101

• Determination of total potentially available nucleosides in human milk from Asian women.

  Nutrition (Burbank, Los Angeles County, Calif.) 20030101

• Clustering of nucleosides in the presence of alkali metals: Biologically relevant quartets of guanosine, deoxyguanosine and uridine observed by ESI-MS/MS.

  Journal of mass spectrometry : JMS 20030101

• A functional single-nucleotide polymorphism in the human cytidine deaminase gene contributing to ara-C sensitivity.

  Pharmacogenetics 20030101

• Hypoxia favours necrotic versus apoptotic shedding of placental syncytiotrophoblast into the maternal circulation.

  Placenta 20030101

• Characterization of micromachined hollow tips for two-dimensional nanoelectrospray mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20030101

• Molecular cloning and characterization of Escherichia coli K12 ygjG gene.

  BMC microbiology 20030101

• Detection of cancer clones in human gastric adenoma by increased DNA-instability and other biomarkers.

  European journal of histochemistry : EJH 20030101

• Cellular pharmacology of D-d4FC, a nucleoside analogue active against drug-resistant HIV.

  Antiviral chemistry & chemotherapy 20030101

• HIV-1 resistance profile of the novel nucleoside reverse transcriptase inhibitor beta-D-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine (Reverset).

  Antiviral chemistry & chemotherapy 20030101

• Expression of activation-induced cytidine deaminase decreases throughout the life.

  Journal of cellular and molecular medicine 20030101

• Effects of base modifications on antisense properties of 2'-O-methoxyethyl and PNA oligonucleotides.

  Antisense & nucleic acid drug development 20030101

• Polymorphisms of IL-4, IL-4R alpha, and AICDA genes in adult allergic asthma.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20030101

• Efficient cross-linking reactions by functional nucleobases capable of in situ activation under neutral conditions.

  Nucleic acids research. Supplement (2001) 20030101

• Biochemical detection of adenosine and cytidine ionization within RNA by interference analysis.

  Nucleic acids research. Supplement (2001) 20030101

• Thionucleotides as inhibitors of ribonucleotide reductase.

  Nucleosides, nucleotides & nucleic acids 20030101

• Commercial-scale synthesis of protected 2'-deoxycytidine and cytidine nucleosides.

  Nucleosides, nucleotides & nucleic acids 20030101

• Intersubunit interactions in human cytidine deaminase.

  Nucleosides, nucleotides & nucleic acids 20030101

• Human cytidine deaminase: understanding the catalytic mechanism.

  Nucleosides, nucleotides & nucleic acids 20030101

• 5-aza-2'-deoxycytidine induces alterations in murine spermatogenesis and pregnancy outcome.

  Journal of andrology 20030101

• Molecular regulation, evolutionary, and functional adaptations associated with C to U editing of mammalian apolipoproteinB mRNA.

  Progress in nucleic acid research and molecular biology 20030101

• Synthesis of new 3'-, 5-, and N(4)-modified 2'-O-methylcytidine libraries on solid support.

  Journal of combinatorial chemistry 20030101

• Nephropathy in a hypercholesterolemic mouse model with streptozotocin-induced diabetes.

  Kidney & blood pressure research 20030101

• Hydrolytic cleavage of purine ribonucleosides in Aspergillus phoenicis.

  Journal of basic microbiology 20030101

• X-linked hyper IgM (HIGM1) in an African kindred: the first report from South Africa.

  BMC pediatrics 20030101

• Forced expression of cytidine deaminase confers sensitivity to capecitabine.

  Oncology 20030101

• Simplicial neighborhood analysis of protein packing (SNAPP): a computational geometry approach to studying proteins.

  Methods in enzymology 20030101

• DNA double strand breaks occur independent of AID in hypermutating Ig genes.

  Clinical & developmental immunology 20030101

• Virus-host interactions: role of HIV proteins Vif, Tat, and Rev.

  AIDS (London, England) 20030101

• Stereoselective synthesis of the 5'-hydroxy-5'-phosphonate derivatives of cytidine and cytosine arabinoside.

  The Journal of organic chemistry 20021227

• Positive and negative transcriptional states of a variegating immunoglobulin heavy chain (IgH) locus are maintained by a cis-acting epigenetic mechanism.

  Journal of immunology (Baltimore, Md. : 1950) 20021215

• Production of cytidine 5'-monophosphate N-acetylneuraminic acid using recombinant Escherichia coli as a biocatalyst.

  Biotechnology and bioengineering 20021205

• Stereochemical course of Escherichia coli RNase H.

  Chembiochem : a European journal of chemical biology 20021202

• Ongoing in vivo immunoglobulin class switch DNA recombination in chronic lymphocytic leukemia B cells.

  Journal of immunology (Baltimore, Md. : 1950) 20021201

• Antitumor activity of troxacitabine (Troxatyl) against anthracycline-resistant human xenografts.

  Cancer chemotherapy and pharmacology 20021201

• Rewriting the information in DNA: RNA editing in kinetoplastids and myxomycetes.

  Current opinion in microbiology 20021201

• Animal models for the study of HBV infection and the evaluation of new anti-HBV strategies.

  Journal of gastroenterology and hepatology 20021201

• Effect of D-amino acids on the functional activity and conformational stability of ribonuclease-A.

  Indian journal of biochemistry & biophysics 20021201

• Analytical and pharmacokinetic studies with 5-chloro-2'-deoxycytidine.

  Biochemical pharmacology 20021115

• Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora.

  Science (New York, N.Y.) 20021115

• Metabolism of capecitabine, an oral fluorouracil prodrug: (19)F NMR studies in animal models and human urine.

  Drug metabolism and disposition: the biological fate of chemicals 20021101

• Inactivation of p16INK4a expression in malignant mesothelioma by methylation.

  Lung cancer (Amsterdam, Netherlands) 20021101

• Cyclic nucleotide content of tobacco BY-2 cells.

  Phytochemistry 20021101

• Does activation-induced deaminase initiate antibody diversification by DNA deamination?

  Trends in genetics : TIG 20021101

• Chemiluminescence response of granulocytes from elite athletes during recovery from one or two intense bouts of exercise.

  European journal of applied physiology 20021101

• Association of (-)786T-C mutation of endothelial nitric oxide synthase gene with insulin resistance.

  Diabetologia 20021101

• Enzymatic cytosine deamination: friend and foe.

  Molecular cell 20021101

• RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators.

  Molecular cell 20021101

• [Minimal functional domain of cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuAc) synthetase from Escherichia coli].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20021101

• An autosampling differential scanning calorimeter instrument for studying molecular interactions.

  Assay and drug development technologies 20021101

• Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota.

  Nature 20021031

• Immunoglobulin genes: generating diversity with AID and UNG.

  Current biology : CB 20021029

• Sequence requirements in the catalytic core of the '10-23' DNA enzyme.

  The Journal of biological chemistry 20021025

• Stereoselective synthesis and antiviral activity of D-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thionucleosides.

  Journal of medicinal chemistry 20021024

• Synthesis and studies of 3'-C-trifluoromethyl nucleoside analogues bearing adenine or cytosine as the base.

  Bioorganic & medicinal chemistry 20021001

• Isolation and enzymatic characterization of lamjapin, the first ribosome-inactivating protein from cryptogamic algal plant (Laminaria japonica A).

  European journal of biochemistry 20021001

• A new cellular system opposing HIV infection: implications for gene transfer?

  Molecular therapy : the journal of the American Society of Gene Therapy 20021001

• Identification and regulation of protein components of the apolipoprotein B mRNA editing enzyme. A complex event.

  Trends in cardiovascular medicine 20021001

• Reduced expression and increased CpG dinucleotide methylation of the rat APOBEC-1 promoter in transgenic rabbits.

  Biochimica et biophysica acta 20020927

• Selective interleukin-12 synthesis defect in 12/15-lipoxygenase-deficient macrophages associated with reduced atherosclerosis in a mouse model of familial hypercholesterolemia.

  The Journal of biological chemistry 20020920

• Solution structure of a luteoviral P1-P2 frameshifting mRNA pseudoknot.

  Journal of molecular biology 20020920

• An artificial guanine that binds cytidine through the cooperative interaction of metal coordination and hydrogen bonding.

  Journal of the American Chemical Society 20020918

• An assay for cytidine 5(')-triphosphate synthetase glutaminase activity using high performance liquid chromatography.

  Analytical biochemistry 20020915

• Retinoic acid reduces the cytotoxicity of cyclopentenyl cytosine in neuroblastoma cells.

  FEBS letters 20020911

• Immunology: the roots of antibody diversity.

  Nature 20020905

• Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

  Nature 20020905

• 13C and (15)N chemical shift tensors in adenosine, guanosine dihydrate, 2'-deoxythymidine, and cytidine.

  Journal of the American Chemical Society 20020904

• AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line.

  Nature immunology 20020901

• A77 1726 induces differentiation of human myeloid leukemia K562 cells by depletion of intracellular CTP pools.

  Molecular pharmacology 20020901

• Does AID need another aid?

  Nature immunology 20020901

• The family Tymoviridae.

  Archives of virology 20020901

• Profiles of pyrimidine biosynthesis, salvage and degradation in disks of potato (Solanum tuberosum L.) tubers.

  Planta 20020901

• Cotranscriptional editing of Physarum mitochondrial RNA requires local features of the native template.

  RNA (New York, N.Y.) 20020901

• Thermodynamic analysis of conserved loop-stem interactions in P1-P2 frameshifting RNA pseudoknots from plant Luteoviridae.

  Biochemistry 20020827

• Zebularine: a novel DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases.

  Journal of molecular biology 20020823

• Severe pyridine nucleotide depletion in fibroblasts from Lesch-Nyhan patients.

  The Biochemical journal 20020815

• HIV: a tough viral nut to crack.

  Nature 20020808

• Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein.

  Nature 20020808

• Where do IgA plasma cells in the gut come from?

  Gut 20020801

• AID and mismatch repair in antibody diversification.

  Nature reviews. Immunology 20020801

• Permeability of Coxiella burnetii to ribonucleosides.

  Microbiology (Reading, England) 20020801

• 5-Azacytidine (5AzC)-induced histopathological changes in the central nervous system of rat fetuses.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20020801

• Isolation from Nocardioides sp. strain CT16, purification, and characterization of a deoxycytidine deaminase extremely thermostable in the presence of D,L-dithiothreitol.

  Bioscience, biotechnology, and biochemistry 20020801

• [Clinical pharmacology of nucleoside analogues].

  Bulletin du cancer 20020801

• Synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol and 2-C-methyl-D-erythritol-4-phosphate.

  The Journal of organic chemistry 20020726

• Synthesis and antiviral evaluation of a mutagenic and non-hydrogen bonding ribonucleoside analogue: 1-beta-D-Ribofuranosyl-3-nitropyrrole.

  Biochemistry 20020723

• AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification.

  Nature 20020704

• Potential mechanisms of resistance to cytarabine in AML patients.

  Leukemia research 20020701

• On the formation kinetics of two-dimensional cytidine films.

  Bioelectrochemistry (Amsterdam, Netherlands) 20020701

• Biochemical and molecular characterization of two cytidine deaminases in the nematode Caenorhabditis elegans.

  The Biochemical journal 20020701

• Identification of active antiviral compounds against a New York isolate of West Nile virus.

  Antiviral research 20020701

• Mutations in coagulation factor XIII A gene in three Turkish patients: two novel mutations and a known insertion.

  British journal of haematology 20020701

• Vibrio cholerae CytR is a repressor of biofilm development.

  Molecular microbiology 20020701

• Sensitivity of human cancer cells to the new anticancer ribo-nucleoside TAS-106 is correlated with expression of uridine-cytidine kinase 2.

  Japanese journal of cancer research : Gann 20020701

• Reconstitution of mRNA editing in yeast using a Gal4-apoB-Gal80 fusion transcript as the selectable marker.

  The Journal of biological chemistry 20020628

• Building blocks for the solution phase synthesis of oligonucleotides: regioselective hydrolysis of 3',5'-Di-O-levulinylnucleosides using an enzymatic approach.

  The Journal of organic chemistry 20020628

• Ultrafast decay of electronically excited singlet cytosine via a pi,pi* to n(O),pi* state switch.

  Journal of the American Chemical Society 20020619

• pH-Stat titration allows the continuous determination of ribonuclease A activity toward cytidine 2',3'-cyclic monophosphate at high substrate concentrations.

  Analytical biochemistry 20020615

• AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts.

  Science (New York, N.Y.) 20020614

• Which endpoints should we use in evaluating the use of novel fluoropyrimidine regimens in colorectal cancer?

  British journal of cancer 20020605

• Enzymatic conformational fluctuations along the reaction coordinate of cytidine deaminase.

  Protein science : a publication of the Protein Society 20020601

• Antidepressant-like effects of cytidine in the forced swim test in rats.

  Biological psychiatry 20020601

• Raman and infrared studies of nucleosides at high pressures: II. Cytidine.

  Journal of biomolecular structure & dynamics 20020601

• Enhancement of cytarabine sensitivity in squamous cell carcinoma cell line transfected with deoxycytidine kinase.

  Archives of otolaryngology--head & neck surgery 20020601

• In vivo mechanisms of resistance to cytarabine in acute myeloid leukaemia.

  British journal of haematology 20020601

• Normal production rate of apolipoprotein B in LDL receptor-deficient mice.

  Arteriosclerosis, thrombosis, and vascular biology 20020601

• Toward RNase inhibitors: thermodynamics of 2'-CMP/RNase-A binding in multi-ion buffer.

  Biochemical pharmacology 20020601

• Measurement of genome wide DNA methylation by reversed-phase high-performance liquid chromatography.

  Methods (San Diego, Calif.) 20020601

• The URH1 uridine ribohydrolase of Saccharomyces cerevisiae.

  Current genetics 20020601

• Cytotoxic activity of 2',2'-difluorodeoxycytidine, 5-aza-2'-deoxycytidine and cytosine arabinoside in cells transduced with deoxycytidine kinase gene.

  Biochemical and biophysical research communications 20020524

• 5-Methyldeoxycytidine monophosphate deaminase and 5-methylcytidyl-DNA deaminase activities are present in human mature sperm cells.

  FEBS letters 20020522

• A unique unnatural base pair between a C analogue, pseudoisocytosine, and an A analogue, 6-methoxypurine, in replication.

  Bioorganic & medicinal chemistry letters 20020520

• Two-dimensional condensation of nucleic acid components at mercury film and gold electrodes.

  Bioelectrochemistry (Amsterdam, Netherlands) 20020515

• Apobec-1 transcription in rat colon cancer: decreased apobec-1 protein production through alterations in polysome distribution and mRNA translation associated with upstream AUGs.

  Biochimica et biophysica acta 20020503

• Comparative evaluation of L-Fd4C and related nucleoside analogs as promising antiviral agents.

  Current medicinal chemistry 20020501

• Distinct nuclear organization, DNA methylation pattern and cytokinin distribution mark juvenile, juvenile-like and adult vegetative apical meristems in peach (Prunus persica (L.) Batsch).

  Journal of experimental botany 20020501

• Nucleoside monophosphates recognition using macrocyclic polyamine bonded phase in capillary electrochromatography.

  Electrophoresis 20020501

• Concurrent analysis of nucleoside reverse transcriptase inhibitors in a pool of endogenous nucleosides by short-end injection-capillary electrochromatography on a beta-cyclodextrin-bonded stationary phase.

  Electrophoresis 20020501

• Cardiovascular effects of intracerebroventricularly injected CDP-choline in normotensive and hypotensive animals: the involvement of cholinergic system.

  Naunyn-Schmiedeberg's archives of pharmacology 20020501

• Organization and transcription of the gene family encoding chlorophyll a/b-binding proteins in Nicotiana sylvestris.

  Gene 20020501

• Serum adenosine deaminase and cytidine deaminase activities in patients with systemic lupus erythematosus.

  Clinical chemistry and laboratory medicine 20020501

• Two proteins essential for apolipoprotein B mRNA editing are expressed from a single gene through alternative splicing.

  The Journal of biological chemistry 20020412

• A cytosolic tRNA with an unmodified adenosine in the wobble position reads a codon ending with the non-complementary nucleoside cytidine.

  Journal of molecular biology 20020405

• Alterations of purine and pyrimidine nucleotide contents in rat corticoencephalic cell cultures following metabolic damage and treatment with openers and blockers of ATP-sensitive potassium channels.

  Neurochemistry international 20020401

• Phosphorylation of linker histones regulates ATP-dependent chromatin remodeling enzymes.

  Nature structural biology 20020401

• Cyclopentenyl cytosine increases the phosphorylation and incorporation into DNA of 1-beta-D-arabinofuranosyl cytosine in a human T-lymphoblastic cell line.

  International journal of cancer 20020401

• Human cytidine deaminase as an ex vivo drug selectable marker in gene-modified primary bone marrow stromal cells.

  Gene therapy 20020401

• Enhancement of DNA ligase I level by gemcitabine in human cancer cells.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020401

• Transient reduction in the tRNA 4-thiouridine content induced by ultraviolet A during post-irradiation growth in Enterobacter cloacae.

  Journal of photochemistry and photobiology. B, Biology 20020401

• Genetic and antigenic analysis of the first A/New Caledonia/20/99-like H1N1 influenza isolates reported in the Americas.

  Emerging infectious diseases 20020401

• Somatic hypermutation of immunoglobulin genes: merging mechanisms for genetic diversity.

  Cell 20020401

• Cellular and biochemical mechanisms of the resistance of human cancer cells to a new anticancer ribo-nucleoside, TAS-106.

  Japanese journal of cancer research : Gann 20020401

• Absence of memory B cells in patients with common variable immunodeficiency.

  Clinical immunology (Orlando, Fla.) 20020401

• Chemosensitization of solid tumors by modulation of resistance mechanisms.

  Current opinion in investigational drugs (London, England : 2000) 20020401

• Pretreatment deoxycytidine kinase levels predict in vivo gemcitabine sensitivity.

  Molecular cancer therapeutics 20020401

• Catalysis by entropic effects: the action of cytidine deaminase on 5,6-dihydrocytidine.

  Biochemistry 20020326

• The AID enzyme induces class switch recombination in fibroblasts.

  Nature 20020321

• pK(a) perturbation in genomic Hepatitis Delta Virus ribozyme catalysis evidenced by nucleotide analogue interference mapping.

  Biochemistry 20020319

• Biochemical and functional characterization of recombinant Rhodnius prolixus platelet aggregation inhibitor 1 as a novel lipocalin with high affinity for adenosine diphosphate and other adenine nucleotides.

  Biochemistry 20020319

• Determination of RNase A/2'-cytidine monophosphate binding affinity and enthalpy by a global fit of thermal unfolding curves.

  Analytical biochemistry 20020315

• Two new isotype-specific switching activities detected for Ig class switching.

  Journal of immunology (Baltimore, Md. : 1950) 20020315

• Characterization of human UMP/CMP kinase and its phosphorylation of D- and L-form deoxycytidine analogue monophosphates.

  Cancer research 20020315

• Role of editing in plant mitochondrial transfer RNAs.

  Gene 20020306

• AID is essential for immunoglobulin V gene conversion in a cultured B cell line.

  Current biology : CB 20020305

• An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22.

  Genomics 20020301

• The editosome for cytidine to uridine mRNA editing has a native complexity of 27S: identification of intracellular domains containing active and inactive editing factors.

  Journal of cell science 20020301

• Crystal structure of the tetrameric cytidine deaminase from Bacillus subtilis at 2.0 A resolution.

  Biochemistry 20020226

• Immunology. One AID to unite them all.

  Science (New York, N.Y.) 20020215

• Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion.

  Science (New York, N.Y.) 20020215

• Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas.

  Nature 20020214

• Methylation of hMLH1 promoter correlates with the gene silencing with a region-specific manner in colorectal cancer.

  British journal of cancer 20020212

• Disruption of HIV-1 integrase-DNA complexes by short 6-oxocytosine-containing oligonucleotides.

  Biochemistry 20020205

• Apolipoprotein B mRNA editing and the reduction in synthesis and secretion of the atherogenic risk factor, apolipoprotein B100 can be effectively targeted through TAT-mediated protein transduction.

  Molecular pharmacology 20020201

• Identification of conjugate adducts formed in the reactions of malonaldehyde-acetaldehyde and malonaldehyde-formaldehyde with cytidine.

  Chemical research in toxicology 20020201

• Molecular basis of 2',3'-dideoxycytidine-induced drug resistance in human cells.

  Molecular and cellular biochemistry 20020201

• The structure of Escherichia coli cytosine deaminase.

  Journal of molecular biology 20020125

• Synthesis and potent anti-HIV activity of L-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thiocytidine.

  Organic letters 20020124

• Pharmacodynamics of citicoline relevant to the treatment of glaucoma.

  Journal of neuroscience research 20020115

• Recognition of the rotavirus mRNA 3' consensus by an asymmetric NSP3 homodimer.

  Cell 20020111

• 15N kinetic isotope effects on uncatalyzed and enzymatic deamination of cytidine.

  Biochemistry 20020108

• C-->U editing of neurofibromatosis 1 mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein B mRNA-editing enzyme.

  American journal of human genetics 20020101

• Rapid photolytic release of cytidine 5'-diphosphate from a coumarin derivative: a new tool for the investigation of ribonucleotide reductases.

  Bioorganic & medicinal chemistry 20020101

• Reversible substrate-induced domain motions in ribonuclease A.

  Proteins 20020101

• The -174 C/G locus affects in vitro/in vivo IL-6 production during aging.

  Experimental gerontology 20020101

• Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals.

  Chemical research in toxicology 20020101

• Molecular mechanism of class switch recombination: linkage with somatic hypermutation.

  Annual review of immunology 20020101

• Identification of domains in apobec-1 complementation factor required for RNA binding and apolipoprotein-B mRNA editing.

  RNA (New York, N.Y.) 20020101

• A role for MAP kinase in the antitumor activity of a nucleoside analog.

  Cancer gene therapy 20020101

• Treatment of chronic hepatitis B.

  Current pharmaceutical design 20020101

• Quantitative assessment of the use of modified nucleoside triphosphates in expression profiling: differential effects on signal intensities and impacts on expression ratios.

  BMC biotechnology 20020101

• Expression profiling of Drosophila imaginal discs.

  Genome biology 20020101

• Comparison of the interaction of uridine, cytidine, and other pyrimidine nucleoside analogues with recombinant human equilibrative nucleoside transporter 2 (hENT2) produced in Saccharomyces cerevisiae.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20020101

• Chemical stability of 2'-deoxy-5-methylisocytidine during oligodeoxynucleotide synthesis and deprotection.

  Nucleosides, nucleotides & nucleic acids 20020101

• Mitochondrial defects in cancer.

  Molecular cancer 20020101

• [Comparative analysis of differentiating and apoptogenic effects of cytidine, thymidine, and guanosine on cells of human erythromyeloleukemic cell line K562].

  Voprosy meditsinskoi khimii 20020101

• Cytidine protonation and base-pair intercalation in nucleic acid structures: the i-motif.

  Nucleic acids research. Supplement (2001) 20020101

• Synthesis of carbocyclic 5'-nor uridine and cytidine derivatives.

  Nucleic acids research. Supplement (2001) 20020101

• 2-Amino-6-vinyl purine as a tool for post synthetic conjugation of DNA with radio-, spin-, fluorescence labels and peptides.

  Nucleic acids research. Supplement (2001) 20020101

• Analysis of single nucleotide polymorphisms in uridine/cytidine kinase gene encoding metabolic enzyme of 3'-ethynylcytidine.

  Nucleic acids research. Supplement (2001) 20020101

• Anticancer mechanisms of 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl) cytosine (ECyd, TAS-106).

  Nucleic acids research. Supplement (2001) 20020101

• Synthesis and potent anti-HIV activity of L-3'-fluoro-2',3'-unsaturated cytidine.

  Organic letters 20011227

• Ethanol stimulates apolipoprotein B mRNA editing in the absence of de novo RNA or protein synthesis.

  Biochemical and biophysical research communications 20011221

• Evidence that the hypermutated M protein of a subacute sclerosing panencephalitis measles virus actively contributes to the chronic progressive CNS disease.

  Virology 20011220

• ENDOR determination of the distance between bleomycin-bound iron and 19F of 2'-fluorocytidine in a DNA target sequence.

  Journal of the American Chemical Society 20011219

• Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor.

  The Journal of biological chemistry 20011214

• A simplified and efficient route to 2'-O, 4'-C-methylene-linked bicyclic ribonucleosides (locked nucleic acid).

  The Journal of organic chemistry 20011214

• Mutagenesis of apobec-1 complementation factor reveals distinct domains that modulate RNA binding, protein-protein interaction with apobec-1, and complementation of C to U RNA-editing activity.

  The Journal of biological chemistry 20011207

• Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin.

  The Journal of biological chemistry 20011207

• AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching.

  Nature 20011206

• ARCD-1, an apobec-1-related cytidine deaminase, exerts a dominant negative effect on C to U RNA editing.

  American journal of physiology. Cell physiology 20011201

• An isothermal titration calorimetric method to determine the kinetic parameters of enzyme catalytic reaction by employing the product inhibition as probe.

  Analytical biochemistry 20011201

• Atomic motion in enzymatic reaction coordinates.

  Current opinion in structural biology 20011201

• Formation of DNA triple helix containing N(4)-(6-aminopyridin-2-yl)-2'-deoxycytidine.

  Journal of biomolecular structure & dynamics 20011201

• Somatic hypermutation in human B cell subsets.

  Springer seminars in immunopathology 20011201

• Terminal defects of B lymphocyte differentiation.

  Current opinion in allergy and clinical immunology 20011201

• Anticodon domain methylated nucleosides of yeast tRNA(Phe) are significant recognition determinants in the binding of a phage display selected peptide.

  Biochemistry 20011127

• Biosynthesis of vitamin B(6) in yeast: incorporation pattern of glucose.

  Journal of the American Chemical Society 20011121

• Quantitation of GSTP1 methylation in non-neoplastic prostatic tissue and organ-confined prostate adenocarcinoma.

  Journal of the National Cancer Institute 20011121

• Isolation, characterization and developmental regulation of the human apobec-1 complementation factor (ACF) gene.

  Biochimica et biophysica acta 20011111

• Essential role of Stat5 for IL-5-dependent IgH switch recombination in mouse B cells.

  Journal of immunology (Baltimore, Md. : 1950) 20011101

• Five-chlorodeoxycytidine, a tumor-selective enzyme-driven radiosensitizer, effectively controls five advanced human tumors in nude mice.

  International journal of radiation oncology, biology, physics 20011101

• Resistance to 2-chloro-2'-deoxyadenosine of the human B-cell leukemia cell line EHEB.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20011101

• The cytostatic- and differentiation-inducing effects of cyclopentenyl cytosine on neuroblastoma cell lines.

  Biochemical pharmacology 20011015

• Cloning and verification of the Lactococcus lactis pyrG gene and characterization of the gene product, CTP synthase.

  The Journal of biological chemistry 20011012

• In situ class switching and differentiation to IgA-producing cells in the gut lamina propria.

  Nature 20011011

• A new reactive nucleoside analogue for highly reactive and selective cross-linking reaction to cytidine under neutral conditions.

  Bioorganic & medicinal chemistry letters 20011008

• Cyclopentenyl cytosine induces apoptosis and increases cytarabine-induced apoptosis in a T-lymphoblastic leukemic cell-line.

  Leukemia research 20011001

• Use of isogenic human cancer cells for high-throughput screening and drug discovery.

  Nature biotechnology 20011001

• Mechanisms of uptake and resistance to troxacitabine, a novel deoxycytidine nucleoside analogue, in human leukemic and solid tumor cell lines.

  Cancer research 20011001

• Phase I trial of weekly gemcitabine at 3-h infusion in refractory, heavily pretreated advanced solid tumors.

  Anti-cancer drugs 20011001

• Cytidine deaminase from two extremophilic bacteria: cloning, expression and comparison of their structural stability.

  Protein engineering 20011001

• Site-bound water and the shortcomings of a less than perfect transition state analogue.

  Biochemistry 20010925

• Kinetic properties of the acylneuraminate cytidylyltransferase from Pasteurella haemolytica A2.

  The Biochemical journal 20010915

• Synthesis and biological evaluation of L- and D-configurations of 2',3'-dideoxy-4'-C-methyl-3'-oxacytidine analogues.

  Bioorganic & medicinal chemistry letters 20010903

• Cloning and expression of uridine/cytidine kinase cDNA from human fibrosarcoma cells.

  International journal of molecular medicine 20010901

• Clonal instability of V region hypermutation in the Ramos Burkitt's lymphoma cell line.

  International immunology 20010901

• Association between a new polymorphism in the activation-induced cytidine deaminase gene and atopic asthma and the regulation of total serum IgE levels.

  The Journal of allergy and clinical immunology 20010901

• A novel affinity chromatography method for the co-purification of deoxycytidine kinase and cytidine deaminase.

  Nucleosides, nucleotides & nucleic acids 20010901

• Selection of drug-resistant transduced cells with cytosine nucleoside analogs using the human cytidine deaminase gene.

  Cancer gene therapy 20010901

• Cleavage of 3',5'-pyrophosphate-linked dinucleotides by ribonuclease A and angiogenin.

  Biochemistry 20010828

• Phosphorylation is a regulatory mechanism in apolipoprotein B mRNA editing.

  The Biochemical journal 20010801

• Hypochlorite-induced damage to nucleosides: formation of chloramines and nitrogen-centered radicals.

  Chemical research in toxicology 20010801

• Solution structure of the pseudoknot of SRV-1 RNA, involved in ribosomal frameshifting.

  Journal of molecular biology 20010727

• Intracellular trafficking determinants in APOBEC-1, the catalytic subunit for cytidine to uridine editing of apolipoprotein B mRNA.

  Experimental cell research 20010715

• A phase I trial of topotecan and gemcitabine administered weekly for 3 consecutive weeks to patients with advanced tumors.

  Cancer 20010715

• Full-sized RanBPM cDNA encodes a protein possessing a long stretch of proline and glutamine within the N-terminal region, comprising a large protein complex.

  Gene 20010711

• Correlated conformational fluctuations during enzymatic catalysis: Implications for catalytic rate enhancement.

  Protein science : a publication of the Protein Society 20010701

• Linking class-switch recombination with somatic hypermutation.

  Nature reviews. Molecular cell biology 20010701

• RNA editing in higher plant plastids: oligoribonucleotide SSCP analysis allows the proof of base conversion directly at the RNA level.

  Current genetics 20010701

• Intracellular phosphorylation of carbocyclic 3-deazaadenosine, an anti-Ebola virus agent.

  Antiviral chemistry & chemotherapy 20010701

• Synthesis, cytotoxicity, and antitumor activity of copper(II) and iron(II) complexes of (4)N-azabicyclo[3.2.2]nonane thiosemicarbazones derived from acyl diazines.

  Journal of medicinal chemistry 20010621

• Superior role of apolipoprotein B48 over apolipoprotein B100 in chylomicron assembly and fat absorption: an investigation of apobec-1 knock-out and wild-type mice.

  The Biochemical journal 20010615

• Structure of a C-rich strand fragment of the human centromeric satellite III: a pH-dependent intercalation topology.

  Journal of molecular biology 20010601

• A novel cellular phenotype for familial hypercholesterolemia due to a defect in polarized targeting of LDL receptor.

  Cell 20010601

• Elucidation of the initial step of oligonucleotide fragmentation in matrix-assisted laser desorption/ionization using modified nucleic acids.

  Journal of the American Society for Mass Spectrometry 20010601

• RNA editing by base deamination: more enzymes, more targets, new mysteries.

  Trends in biochemical sciences 20010601

• Nucleoside analogues: mechanisms of drug resistance and reversal strategies.

  Leukemia 20010601

• Screening of differentially expressed genes in 5-fluorouracil-resistant human gastrointestinal tumor cells.

  Japanese journal of cancer research : Gann 20010601

• An efficient method for the preparation of 1'alpha-branched-chain sugar pyrimidine ribonucleosides from uridine: the first conversion of a natural nucleoside into 1'-substituted ribonucleosides.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20010601

• Effects of tomato extract on human platelet aggregation in vitro.

  Platelets 20010601

• The RNA i-motif.

  Journal of molecular biology 20010525

• Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases.

  Molecular pharmacology 20010501

• Frequencies of amino acid strings in globular protein sequences indicate suppression of blocks of consecutive hydrophobic residues.

  Protein science : a publication of the Protein Society 20010501

• Effects of purine and pyrimidine nucleotides on intracellular Ca2+ in human eosinophils: activation of purinergic P2Y receptors.

  The Journal of allergy and clinical immunology 20010501

• A base-labile protecting group (fluorenylmethoxycarbonyl) for the 5'-hydroxy function of nucleosides.

  Current protocols in nucleic acid chemistry 20010501

• 2'-Hydroxyl-protecting groups that are either photochemically labile or sensitive to fluoride ions.

  Current protocols in nucleic acid chemistry 20010501

• Hydrogen-bond-mediated photoinduced electron-transfer: novel dimethylaniline-anthracene ensembles formed via Watson-Crick base-pairing.

  Journal of the American Chemical Society 20010425

• Thiosugars. Part 9: synthesis and biological evaluation of some 4'-thio-L-arabino nucleoside analogues.

  Bioorganic & medicinal chemistry letters 20010423

• Synthesis of novel 3'-C-methylene thymidine and 5-methyluridine/cytidine H-phosphonates and phosphonamidites for new backbone modification of oligonucleotides.

  The Journal of organic chemistry 20010420

• Increased transcription levels induce higher mutation rates in a hypermutating cell line.

  Journal of immunology (Baltimore, Md. : 1950) 20010415

• Improvement in precision of the liquid chromatographic-electrospray ionization tandem mass spectrometric analysis of 3'-C-ethynylcytidine in rat plasma.

  Journal of chromatography. B, Biomedical sciences and applications 20010415

• Two-hybrid cloning identifies an RNA-binding protein, GRY-RBP, as a component of apobec-1 editosome.

  Biochemical and biophysical research communications 20010413

• Enhanced ribonucleotide incorporation by an O-helix mutant of Thermus aquaticus DNA polymerase I.

  Mutation research 20010404

• Towards an understanding of somatic hypermutation.

  Current opinion in immunology 20010401

• Maedi-visna virus, a model for in vitro testing of potential anti-HIV drugs.

  Comparative immunology, microbiology and infectious diseases 20010401

• Molecular mechanisms of apolipoprotein B mRNA editing.

  Current opinion in lipidology 20010401

• Active oligonucleotides incorporating alkylating an agent as potential sequence- and base selective modifier of gene expression.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010401

• Ischemic brain injury caused by interrupted versus uninterrupted occlusion in hypotensive rats with subarachnoid hemorrhage: neuroprotective effects of citicoline.

  Archives of physiology and biochemistry 20010401

• Identification of GRY-RBP as an apolipoprotein B RNA-binding protein that interacts with both apobec-1 and apobec-1 complementation factor to modulate C to U editing.

  The Journal of biological chemistry 20010330

• Hypochlorous acid produced by the myeloperoxidase system of human phagocytes induces covalent cross-links between DNA and protein.

  Biochemistry 20010327

• Correlation between processing efficiency for ribonuclease P minimal substrates and conformation of the nucleotide -1 at the cleavage position.

  Biochemistry 20010320

• Cytosolic high K(m) 5'-nucleotidase and 5'(3')-deoxyribonucleotidase in substrate cycles involved in nucleotide metabolism.

  The Journal of biological chemistry 20010302

• Ontogenic and longitudinal activity of Na(+)-nucleoside transporters in the human intestine.

  American journal of physiology. Gastrointestinal and liver physiology 20010301

• Na+ reabsorption in cultured rat epididymal epithelium via the Na+/nucleoside cotransporter.

  Biology of reproduction 20010301

• Antitumor activity and pharmacokinetics of TAS-106, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine.

  Japanese journal of cancer research : Gann 20010301

• Characterization of sialyltransferase mutants using surface plasmon resonance.

  Glycobiology 20010301

• Comparative study of a novel nucleoside analogue (Troxatyl, troxacitabine, BCH-4556) and AraC against leukemic human tumor xenografts expressing high or low cytidine deaminase activity.

  Cancer chemotherapy and pharmacology 20010301

• The effect of cytidine on the structure and function of an RNA ligase ribozyme.

  RNA (New York, N.Y.) 20010301

• Stability and structure of RNA duplexes containing isoguanosine and isocytidine.

  Journal of the American Chemical Society 20010221

• Selective reaction to a flipping cytidine of the duplex DNA mediated by triple helix formation.

  Bioorganic & medicinal chemistry letters 20010212

• A novel proton-dependent nucleoside transporter, CeCNT3, from Caenorhabditis elegans.

  Molecular pharmacology 20010201

• Differential gene expression profiles of scirrhous gastric cancer cells with high metastatic potential to peritoneum or lymph nodes.

  Cancer research 20010201

• Immunoglobulin E and its regulators.

  Current opinion in allergy and clinical immunology 20010201

• Probing structure and dynamics of DNA with 2-aminopurine: effects of local environment on fluorescence.

  Biochemistry 20010130

• Temperature is a cue for gene expression in the post-infective L3 of the parasitic nematode Brugia pahangi.

  Molecular and biochemical parasitology 20010115

• The RihA, RihB, and RihC ribonucleoside hydrolases of Escherichia coli. Substrate specificity, gene expression, and regulation.

  The Journal of biological chemistry 20010112

• Purification method for the isolation of monophosphate nucleotides from Champagne wine and their identification by mass spectrometry.

  Journal of chromatography. A 20010112

• Simultaneous treatment with 1-beta-D-arabinofuranosylcytosine and daunorubicin induces cross-resistance to both drugs due to a combination-specific mechanism in HL60 cells.

  Cancer research 20010101

• Induction of differentiation of acute promyelocytic leukemia cells by a cytidine deaminase-resistant analogue of 1-beta-D-arabinofuranosylcytosine, 1-(2-deoxy-2-methylene-beta-D-erythro-pentofuranosyl)cytidine.

  Cancer research 20010101

• Uptake properties of lamivudine (3TC) by a continuous renal epithelial cell line.

  Canadian journal of physiology and pharmacology 20010101

• Reduced hydrolysis of amelogenin may result in X-linked amelogenesis imperfecta.

  Matrix biology : journal of the International Society for Matrix Biology 20010101

• [DNA-(N4-cytosine)-methyltransferase from Bacillus amyloliquefaciens: kinetic and substrate binding properties].

  Molekuliarnaia biologiia 20010101

• UAG readthrough in mammalian cells: effect of upstream and downstream stop codon contexts reveal different signals.

  BMC molecular biology 20010101

• Comments on: cylopentenyl cytosine inhibits cytidine triphosphate synthetase in paediatric acute non-lymphocytic leukaemia: a promising target for chemotherapy. A.C. Verschuur et al. Eur J Cancer 2000, 36, 627-635.

  European journal of cancer (Oxford, England : 1990) 20010101

• Clinical pharmacokinetics of capecitabine.

  Clinical pharmacokinetics 20010101

• Polymorphisms in the Mn-SOD and EC-SOD genes and their relationship to diabetic neuropathy in type 1 diabetes mellitus.

  BMC medical genetics 20010101

• Functional production of mammalian concentrative nucleoside transporters in Saccharomyces cerevisiae.

  Molecular membrane biology 20010101

• Treatment of advanced hepatocellular carcinoma with biweekly high-dose gemcitabine.

  Oncology 20010101

• Cytostatic effect of inostamycin, an inhibitor of cytidine 5'-diphosphate 1,2-diacyl-sn-glycerol (CDP-DG): inositol transferase, on oral squamous cell carcinoma cell lines.

  Cell biology international 20010101

• Comparative histochemical study of Bowen's disease and actinic keratosis: preserved normal basal cells in Bowen's disease.

  European journal of histochemistry : EJH 20010101

• Synthetic studies to improve the deuterium labelling in nucleosides for facilitating structural studies of large RNAs by high-field NMR spectroscopy.

  Nucleosides, nucleotides & nucleic acids 20010101

• 6-oxocytidine containing oligonucleotides inhibit the HIV-1 integrase in vitro.

  Nucleosides, nucleotides & nucleic acids 20010101

• 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106)1: antitumor effect and mechanism of action.

  Nucleosides, nucleotides & nucleic acids 20010101

• Unnatural enantiomers of 5-azacytidine analogues: syntheses and enzymatic properties.

  Nucleosides, nucleotides & nucleic acids 20010101

• Site-directed alkylation to cytidine within duplex by the oligonucleotides containing functional nucleobases.

  Nucleosides, nucleotides & nucleic acids 20010101

• Mutant loxP vectors for selectable marker recycle and conditional knock-outs.

  BMC biotechnology 20010101

• CDP-choline, but not cytidine, protects hippocampal CA1 neurones in the gerbil following transient forebrain ischaemia.

  Folia neuropathologica 20010101

• A combined in vitro/in vivo selection for polymerases with novel promoter specificities.

  BMC biotechnology 20010101

• Visualization of muscarinic receptor-mediated phosphoinositide turnover in the hippocampus of young and aged, learning-impaired Long Evans rats.

  Hippocampus 20010101

• A new coupling method for the synthesis of oligodeoxyribonucleotides based on protection by protonation of nucleoside bases.

  Nucleic acids research. Supplement (2001) 20010101

• Efficient cross-linking to cytidine under neutral conditions using the 2-amino-6-vinylpurine derivative having an additional activating group.

  Nucleic acids research. Supplement (2001) 20010101

• Binding specificities of the mismatch binding protein, MutS, to oligonucleotides containing modified bases.

  Nucleic acids research. Supplement (2001) 20010101

• Anticancer molecular mechanism of 3'-ethynylcytidine (ECyd).

  Nucleic acids research. Supplement (2001) 20010101

• Synthesis, Characterization and Antiviral Properties of Pd(II) Complexes With Penciclovir.

  Metal-based drugs 20010101

• Molecular cloning and functional characterization of inhibitor-sensitive (mENT1) and inhibitor-resistant (mENT2) equilibrative nucleoside transporters from mouse brain.

  The Biochemical journal 20001201

• Synthesis and evaluation of 'AZT-HEPT', 'AZT-pyridinone', and 'ddC-HEPT' conjugates as inhibitors of HIV reverse transcriptase.

  Journal of medicinal chemistry 20000518

• Differential transport of cytosine-containing nucleosides by recombinant human concentrative nucleoside transporter protein hCNT1.

  Nucleosides, nucleotides & nucleic acids 20000101

• Antisense oligonucleotide inhibition of hepatitis C virus (HCV) gene expression in livers of mice infected with an HCV-vaccinia virus recombinant.

  Antimicrobial agents and chemotherapy 19990201

• Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissues.

  The Journal of biological chemistry 19971107

• Prevention of simian immunodeficiency virus, SIVsm, or HIV-2 infection in cynomolgus monkeys by pre- and postexposure administration of BEA-005.

  AIDS (London, England) 19970201

• Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1).

  The American journal of physiology 19970201

• Synergistic antiviral action of ribonucleotide reductase inhibitors and 3'-azido-3'-deoxythymidine on HIV type 1 infection in vitro.

  AIDS research and human retroviruses 19960520

• Phase I clinical trial of continuous infusion cyclopentenyl cytosine.

  Cancer chemotherapy and pharmacology 19950101

• Inhibition of ribonucleotide reductase by 2'-substituted deoxycytidine analogs: possible application in AIDS treatment.

  Proceedings of the National Academy of Sciences of the United States of America 19940830

• Chemistry and anti-HIV properties of 2'-fluoro-2',3'-dideoxyarabinofuranosylpyrimidines.

  Journal of medicinal chemistry 19920612

• Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro.

  Antiviral research 19910701

• Broad-spectrum antiviral and cytocidal activity of cyclopentenylcytosine, a carbocyclic nucleoside targeted at CTP synthetase.

  Biochemical pharmacology 19910615

• Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine.

  Molecular pharmacology 19901001

• Broad-spectrum antiviral activity of carbodine, the carbocyclic analogue of cytidine.

  Biochemical pharmacology 19900115

• 1-(2,3-Anhydro-beta-D-lyxofuranosyl)cytosine derivatives as potential inhibitors of the human immunodeficiency virus.

  Journal of medicinal chemistry 19880701

• Uridine reverses the toxicity of 3'-azido-3'-deoxythymidine in normal human granulocyte-macrophage progenitor cells in vitro without impairment of antiretroviral activity.

  Antimicrobial agents and chemotherapy 19880701

• Synthesis and antiviral evaluation of carbocyclic analogues of 2'-azido- and 2'-amino-2'-deoxycytidine.

  Journal of medicinal chemistry 19880201

• Comparative efficacy of broad-spectrum antiviral agents as inhibitors of rotavirus replication in vitro.

  Antiviral research 19860101

• Characterization of mouse and human monoclonal antibodies cross-reactive with SLE serum antibodies to guanosine.

  Journal of immunology (Baltimore, Md. : 1950) 19840601

• Evaluation of carbodine, the carbocyclic analog of cytidine, and related carbocyclic analogs of pyrimidine nucleosides for antiviral activity against human influenza Type A viruses.

  Antimicrobial agents and chemotherapy 19811201

• Cellular differentiation, cytidine analogs and DNA methylation.

  Cell 19800501

• Inhibition of urethan induced lung tumour growth in strain A mice by 5-methyl cytidine.

  Cytobios 19800101

• Letter: Myelotoxicity and orthostatic hypotension of cyclocytidine (NSC-145668).

  Cancer treatment reports 19760301

• Reactions of cytosine and cytidine with O-substituted hydroxylamines.

  Journal of the Chemical Society. Perkin transactions 1 19750101