6640-22-8 | Pamoic acid disodium salt

Packsize	Purity	Availability	Price	Discounted Price
5g	95%	in stock	$19.00	$13.00
25g	95%	in stock	$34.00	$24.00
100g	95%	in stock	$79.00	$55.00
500g	95%	in stock	$330.00	$231.00

Description

• Catalog Number: AB78065
• Chemical Name: Pamoic acid disodium salt
• CAS Number: 6640-22-8
• Molecular Formula: C23H14Na2O6
• Molecular Weight: 432.3332
• MDL Number: MFCD00036183
• SMILES: [O-]C(=O)c1cc2ccccc2c(c1O)Cc1c(O)c(cc2c1cccc2)C(=O)[O-].[Na+].[Na+]

Computed Properties

• Complexity: 569
• Covalently-Bonded Unit Count: 3
• Heavy Atom Count: 31
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4

Literature

• Mind your salts: when the inactive constituent isn't.

  Molecular pharmacology 20101001

• Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity.

  Molecular pharmacology 20101001

• Development and evaluation of a 68Ga labeled pamoic acid derivative for in vivo visualization of necrosis using positron emission tomography.

  Bioorganic & medicinal chemistry 20100715

• Structural insights on the pamoic acid and the 8 kDa domain of DNA polymerase beta complex: towards the design of higher-affinity inhibitors.

  BMC structural biology 20080101

• Necrosis avidity of (99m)Tc(CO)3-labeled pamoic acid derivatives: synthesis and preliminary biological evaluation in animal models of necrosis.

  Bioconjugate chemistry 20070101

• Identification of small molecule synthetic inhibitors of DNA polymerase beta by NMR chemical shift mapping.

  The Journal of biological chemistry 20040917

• Effects of imipramine on ion channels and proliferation of IGR1 melanoma cells.

  The Journal of membrane biology 20020715