66640-86-6 | Biotin hydrazide

Packsize	Purity	Availability	Price	Discounted Price
25mg	>98.0%(HPLC)	in stock	$35.00	$24.00
100mg	95%	in stock	$54.00	$38.00
250mg	95%	in stock	$106.00	$75.00
1g	95%	in stock	$219.00	$153.00
5g	95%	in stock	$667.00	$467.00
10g	95%	in stock	$993.00	$695.00
25g	95%	in stock	$2,004.00	$1,403.00

Description

• Catalog Number: AI54664
• Chemical Name: Biotin hydrazide
• CAS Number: 66640-86-6
• Molecular Formula: C10H18N4O2S
• Molecular Weight: 258.3405
• MDL Number: MFCD00078532
• SMILES: NNC(=O)CCCC[C@@H]1SC[C@H]2[C@@H]1NC(=O)N2

Computed Properties

• Complexity: 313
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 3
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 5
• XLogP3: -0.7

Literature

• Comparing the efficiencies of hydrazide labels in the study of protein carbonylation in human serum albumin.

  Analytical and bioanalytical chemistry 20120901

• Evaluation of three simple direct or indirect carbonyl detection methods for characterization of oxidative modifications of proteins.

  Toxicology mechanisms and methods 20120501

• Sensitive chemiluminescent imaging for chemoselective analysis of glycan expression on living cells using a multifunctional nanoprobe.

  Analytical chemistry 20120207

• Ethanol-induced oxidative stress via the CYP2E1 pathway disrupts adiponectin secretion from adipocytes.

  Alcoholism, clinical and experimental research 20120201

• Chemo-enzymatic modification of poly-N-acetyllactosamine (LacNAc) oligomers and N,N-diacetyllactosamine (LacDiNAc) based on galactose oxidase treatment.

  Beilstein journal of organic chemistry 20120101

• Determining the effects of antioxidants on oxidative stress induced carbonylation of proteins.

  Analytical chemistry 20111215

• Differential carbonylation of proteins as a function of in vivo oxidative stress.

  Journal of proteome research 20110902

• Protein glycosylation in Helicobacter pylori: beyond the flagellins?

  PloS one 20110101

• Proteomic identification of carbonylated proteins and their oxidation sites.

  Journal of proteome research 20100806

• Profiling carbonylated proteins in human plasma.

  Journal of proteome research 20100305

• Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease.

  Methods in molecular biology (Clifton, N.J.) 20100101

• Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1.

  PloS one 20100101

• Post-genomics and skin inflammation.

  Mediators of inflammation 20100101

• Staphylococcal peptidoglycan co-localizes with Nod2 and TLR2 and activates innate immune response via both receptors in primary murine keratinocytes.

  PloS one 20100101

• Covalent binding of penicillamine to macrophages: implications for penicillamine-induced autoimmunity.

  Chemical research in toxicology 20090701

• Analysis of oxidative modification of proteins.

  Current protocols in protein science 20090401

• Analysis of oxidative modification of proteins.

  Current protocols in protein science 20090201

• Detection of protein carbonyls by means of biotin hydrazide-streptavidin affinity methods.

  Methods in molecular biology (Clifton, N.J.) 20090101

• Fast in vitro translation system immobilized on a surface via specific biotinylation of the ribosome.

  Biological chemistry 20080901

• One-step photochemical attachment of NHS-terminated monolayers onto silicon surfaces and subsequent functionalization.

  Langmuir : the ACS journal of surfaces and colloids 20080805

• Development of an enzyme-linked immunosorbent assay (ELISA)-like fluorescence assay to investigate the interactions of glycosaminoglycans to cells.

  Analytica chimica acta 20080623

• Introducing genetically encoded aldehydes into proteins.

  Nature chemical biology 20070601

• Substrate profiling of protein tyrosine phosphatase PTP1B by screening a combinatorial peptide library.

  Journal of the American Chemical Society 20070502

• Identification of carbonylated proteins from enriched rat skeletal muscle mitochondria using affinity chromatography-stable isotope labeling and tandem mass spectrometry.

  Proteomics 20070401

• Protein-RNA cross-linking in the ribosomes of yeast under oxidative stress.

  Journal of proteome research 20061201

• Biotinylation of glycan chains in beta2 glycoprotein I induces dimerization of the molecule and its detection by the human autoimmune anti-cardiolipin antibody EY2C9.

  The Biochemical journal 20060101

• Primary glia expressing the G93A-SOD1 mutation present a neuroinflammatory phenotype and provide a cellular system for studies of glial inflammation.

  Journal of neuroinflammation 20060101

• Oxidation and biotinylation of beta 2 glycoprotein I glycan chains induce an increase in its affinity for anionic phospholipids similar to that obtained by the addition of anti-beta 2 glycoprotein I or anti-cardiolipin antibodies.

  Journal of immunological methods 20050501

• Affinity chromatographic selection of carbonylated proteins followed by identification of oxidation sites using tandem mass spectrometry.

  Analytical chemistry 20050415

• Proteomic analysis of carbonylated proteins in two-dimensional gel electrophoresis using avidin-fluorescein affinity staining.

  Electrophoresis 20040501

• Independently-addressable micron-sized biosensor elements.

  Biosensors & bioelectronics 20030901

• Surface engineering of living myoblasts via selective periodate oxidation.

  Biotechnology and bioengineering 20030330

• Directional degradation of beta-chitin by chitinase A1 revealed by a novel reducing end labelling technique.

  FEBS letters 20020116

• Kinetic parameters for small-molecule drug delivery by covalent cell surface targeting.

  Biochimica et biophysica acta 20011205