67604-48-2 | 5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one

Packsize	Purity	Availability	Price	Discounted Price
10g	98%	in stock	$13.00	$9.00
100g	98%	in stock	$129.00	$90.00
500g	98%	in stock	$409.00	$286.00

Description

• Catalog Number: AH14118
• Chemical Name: 5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
• CAS Number: 67604-48-2
• Molecular Formula: C15H12O5
• Molecular Weight: 272.25278
• MDL Number: MFCD00006844
• SMILES: Oc1ccc(cc1)C1CC(=O)c2c(O1)cc(cc2O)O

Computed Properties

• Complexity: 363
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 1
• Undefined Atom Stereocenter Count: 1
• XLogP3: 2.4

Literature

• Drug interaction study of flavonoids toward CYP3A4 and their quantitative structure activity relationship (QSAR) analysis for predicting potential effects.

  Toxicology letters 20180915

• Isolated mangiferin and naringenin exert antidiabetic effect via PPAR(γ)/GLUT4 dual agonistic action with strong metabolic regulation.

  Chemico-biological interactions 20180125

• Naringenin causes ASK1-induced apoptosis via reactive oxygen species in human pancreatic cancer cells.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20170101

• POSSIBLE REGULATION OF LDL-RECEPTOR BY NARINGENIN IN HEPG2 HEPATOMA CELL LINE.

  African journal of traditional, complementary, and alternative medicines : AJTCAM 20170101

• Apigenin Inhibits Cancer Stem Cell-Like Phenotypes in Human Glioblastoma Cells via Suppression of c-Met Signaling.

  Phytotherapy research : PTR 20161101

• PVP- coated naringenin nanoparticles for biomedical applications - In vivo toxicological evaluations.

  Chemico-biological interactions 20160925

• Inhibition of human and rat CYP1A1 enzyme by grapefruit juice compounds.

  Toxicology letters 20160906

• Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries.

  Toxicological sciences : an official journal of the Society of Toxicology 20160501

• Resveratrol stimulates cyclic AMP response element mediated gene transcription.

  Molecular nutrition & food research 20160201

• Naringenin suppresses TPA-induced tumor invasion by suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells.

  Chemico-biological interactions 20150625

• Functional Characterization of Cucurbitadienol Synthase and Triterpene Glycosyltransferase Involved in Biosynthesis of Mogrosides from Siraitia grosvenorii.

  Plant & cell physiology 20150601

• Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein.

  Toxicological sciences : an official journal of the Society of Toxicology 20150201

• Screening of a chemical library reveals novel PXR-activating pharmacologic compounds.

  Toxicology letters 20150105

• Examination of changes in enzyme activities of erythrocyte glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in rats given Naringenin and Lead acetate.

  Journal of biochemical and molecular toxicology 20150101

• Investigation of the effects of some phenolic compounds on the activities of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase from human erythrocytes.

  Journal of biochemical and molecular toxicology 20141101

• Naringenin exerts cytoprotective effect against paraquat-induced toxicity in human bronchial epithelial BEAS-2B cells through NRF2 activation.

  Journal of microbiology and biotechnology 20140501

• Dietary flavonoids fisetin and myricetin: dual inhibitors of Plasmodium falciparum falcipain-2 and plasmepsin II.

  Fitoterapia 20140401

• Naringenin inhibits α-glucosidase activity: a promising strategy for the regulation of postprandial hyperglycemia in high fat diet fed streptozotocin induced diabetic rats.

  Chemico-biological interactions 20140305

• Xenoestrogens alter estrogen receptor (ER) α intracellular levels.

  PloS one 20140101

• Protective effects of naringenin on carbon tetrachloride-induced acute nephrotoxicity in mouse kidney.

  Chemico-biological interactions 20130925

• Flavanoids induce expression of the suppressor of cytokine signalling 3 (SOCS3) gene and suppress IL-6-activated signal transducer and activator of transcription 3 (STAT3) activation in vascular endothelial cells.

  The Biochemical journal 20130901

• Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions.

  Journal of pharmaceutical sciences 20130901

• Protective effect of naringenin on hepatic and renal dysfunction and oxidative stress in arsenic intoxicated rats.

  Molecular biology reports 20130501

• The dietary flavonoids naringenin and quercetin acutely impair glucose metabolism in rodents possibly via inhibition of hypothalamic insulin signalling.

  The British journal of nutrition 20130328

• Identifying safer anti-wear triaryl phosphate additives for jet engine lubricants.

  Chemico-biological interactions 20130325

• Naringenin prevents high glucose-induced mitochondria-mediated apoptosis involving AIF, Endo-G and caspases.

  Apoptosis : an international journal on programmed cell death 20130101

• Participation of antioxidant and cholinergic system in protective effect of naringenin against type-2 diabetes-induced memory dysfunction in rats.

  Neuroscience 20121213

• Comparison between 8-prenylnarigenin and narigenin concerning their activities on promotion of rat bone marrow stromal cells' osteogenic differentiation in vitro.

  Cell proliferation 20121201

• Divergent antiviral effects of bioflavonoids on the hepatitis C virus life cycle.

  Virology 20121125

• Rat α-Fetoprotein binding affinities of a large set of structurally diverse chemicals elucidated the relationships between structures and binding affinities.

  Chemical research in toxicology 20121119

• Enhancing the anticancer effect of the histone deacetylase inhibitor by activating transglutaminase.

  European journal of cancer (Oxford, England : 1990) 20121101

• A novel class of sticky peel and light green mutations causes cuticle deficiency in leaves and fruits of tomato (Solanum lycopersicum).

  Planta 20121101

• The potential bioproduction of the pharmaceutical agent sakuranetin, a flavonoid phytoalexin in rice.

  Bioengineered 20121101

• Naringenin and quercetin reverse the effect of hypobaric hypoxia and elicit neuroprotective response in the murine model.

  Brain research 20121024

• Antidepressant-like behavioral, neurochemical and neuroendocrine effects of naringenin in the mouse repeated tail suspension test.

  Progress in neuro-psychopharmacology & biological psychiatry 20121001

• Selected nutraceutic screening by therapeutic effects on doxorubicin-induced chronic kidney disease.

  Molecular nutrition & food research 20121001

• Changes in the polyphenol profile of tomato juices processed by pulsed electric fields.

  Journal of agricultural and food chemistry 20120926

• Grapefruit juice and its constituents augment the effect of low pH on inhibition of survival and adherence to intestinal epithelial cells of Salmonella enterica serovar Typhimurium PT193.

  International journal of food microbiology 20120903

• Antihyperglycemic and antioxidant effects of a flavanone, naringenin, in streptozotocin-nicotinamide-induced experimental diabetic rats.

  Journal of physiology and biochemistry 20120901

• Molluscicidal activity of Aglaia duperreana and the constituents of its twigs and leaves.

  Fitoterapia 20120901

• Naringenin inhibits TNF-α induced VSMC proliferation and migration via induction of HO-1.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120901

• Anti-inflammatory role of naringenin in rats with ethanol induced liver injury.

  Toxicology mechanisms and methods 20120901

• The naringenin-induced proapoptotic effect in breast cancer cell lines holds out against a high bisphenol a background.

  IUBMB life 20120801

• UPLC-MS/MS determination of paeoniflorin, naringin, naringenin and glycyrrhetinic acid in rat plasma and its application to a pharmacokinetic study after oral administration of Si-Ni-San decoction.

  Journal of pharmaceutical and biomedical analysis 20120701

• Naringenin attenuates the release of pro-inflammatory mediators from lipopolysaccharide-stimulated BV2 microglia by inactivating nuclear factor-κB and inhibiting mitogen-activated protein kinases.

  International journal of molecular medicine 20120701

• Naringin attenuates enhanced cough, airway hyperresponsiveness and airway inflammation in a guinea pig model of chronic bronchitis induced by cigarette smoke.

  International immunopharmacology 20120701

• Flavonoids protect pancreatic beta-cells from cytokines mediated apoptosis through the activation of PI3-kinase pathway.

  Cytokine 20120701

• A genome-wide regulatory framework identifies maize pericarp color1 controlled genes.

  The Plant cell 20120701

• Anticomplement and antimicrobial activities of flavonoids from Entada phaseoloides.

  Natural product communications 20120701

• ID-CUBE direct analysis in real time high-resolution mass spectrometry and its capabilities in the identification of phenolic components from the green leaves of Bergenia crassifolia L.

  Rapid communications in mass spectrometry : RCM 20120615

• Protective effect of naringenin against lead-induced oxidative stress in rats.

  Biological trace element research 20120601

• Purification and identification of naringenin 7-O-methyltransferase, a key enzyme in biosynthesis of flavonoid phytoalexin sakuranetin in rice.

  The Journal of biological chemistry 20120601

• Real-time separation of natural products by ultrafast 2D NMR coupled to on-line HPLC.

  The Analyst 20120521

• Inhibition of hepatic uptake transporters by flavonoids.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120512

• [Chemical constituents of Phymatopteris hastate and their antioxidant activity].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120501

• Interaction of antioxidant flavonoids with calf thymus DNA analyzed by spectroscopic and electrochemical methods.

  Journal of pharmaceutical and biomedical analysis 20120407

• SULT1A3-mediated regiospecific 7-O-sulfation of flavonoids in Caco-2 cells can be explained by the relevant molecular docking studies.

  Molecular pharmaceutics 20120402

• Sorghum phenolics demonstrate estrogenic action and induce apoptosis in nonmalignant colonocytes.

  Nutrition and cancer 20120401

• An efficient way from naringenin to carthamidine and isocarthamidine by Aspergillus niger.

  World journal of microbiology & biotechnology 20120401

• Regulation of inflammatory cytokines in lipopolysaccharide-stimulated RAW 264.7 murine macrophage by 7-O-methyl-naringenin.

  Molecules (Basel, Switzerland) 20120322

• Dietary flavonoid naringenin induces regulatory T cells via an aryl hydrocarbon receptor mediated pathway.

  Journal of agricultural and food chemistry 20120307

• A naturally occurring naringenin derivative exerts potent bone anabolic effects by mimicking oestrogen action on osteoblasts.

  British journal of pharmacology 20120301

• Contribution of flavonoids and catechol to the reduction of ICAM-1 expression in endothelial cells by a standardised Willow bark extract.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20120215

• (2S)-naringenin from Typha angustata inhibits vascular smooth muscle cell proliferation via a G0/G1 arrest.

  Journal of ethnopharmacology 20120215

• In vitro antileishmanial and antitrypanosomal activities of flavanones from Baccharis retusa DC. (Asteraceae).

  Experimental parasitology 20120201

• [Preparation of naringenin by enzymolysis of naringin-HP-beta-CD].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120201

• Simultaneous determination of naringin, hesperidin, neohesperidin, naringenin and hesperetin of Fractus aurantii extract in rat plasma by liquid chromatography tandem mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20120125

• Anti-inflammatory and antifibrotic effects of naringenin in diabetic mice.

  Journal of agricultural and food chemistry 20120111

• ¹H-NMR simultaneous identification of health-relevant compounds in propolis extracts.

  Phytochemical analysis : PCA 20120101

• Removing allosteric feedback inhibition of tomato 4-coumarate:CoA ligase by directed evolution.

  The Plant journal : for cell and molecular biology 20120101

• Synthesis, characterization and antioxidant capacity of naringenin-oxime.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120101

• Investigation of the anxiolytic effects of naringenin, a component of Mentha aquatica, in the male Sprague-Dawley rat.

  Holistic nursing practice 20120101

• Toxicokinetics of naringin and its metabolite naringenin after 180-day repeated oral administration in beagle dogs assayed by a rapid resolution liquid chromatography/tandem mass spectrometric method.

  Journal of Asian natural products research 20120101

• Combinatorial antitumor effect of naringenin and curcumin elicit angioinhibitory activities in vivo.

  Nutrition and cancer 20120101

• Global transcriptome analysis reveals distinct expression among duplicated genes during sorghum-interaction.

  BMC plant biology 20120101

• Naringenin inhibits the aggregation of expanded polyglutamine tract-containing protein through the induction of endoplasmic reticulum chaperone GRP78.

  Biological & pharmaceutical bulletin 20120101

• Naringenin suppresses the production of thymic stromal lymphopoietin through the blockade of RIP2 and caspase-1 signal cascade in mast cells.

  European journal of pharmacology 20111205

• Naringenin modulates circulatory lipid peroxidation, anti-oxidant status and hepatic alcohol metabolizing enzymes in rats with ethanol induced liver injury.

  Fundamental & clinical pharmacology 20111201

• Photosynthetic Bradyrhizobium Sp. strain ORS285 synthesizes 2-O-methylfucosylated lipochitooligosaccharides for nod gene-dependent interaction with Aeschynomene plants.

  Molecular plant-microbe interactions : MPMI 20111201

• An in vitro transport model for rapid screening and predicting the permeability of candidate compounds at blood-brain barrier.

  Journal of Asian natural products research 20111201

• Double directional adjusting estrogenic effect of naringin from Rhizoma drynariae (Gusuibu).

  Journal of ethnopharmacology 20111118

• Citrus flavanone naringenin enhances melanogenesis through the activation of Wnt/β-catenin signalling in mouse melanoma cells.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20111115

• Analysis of flavonoids by capillary zone electrophoresis with electrokinetic supercharging.

  The Analyst 20111107

• Synergic effect of α-tocopherol and naringenin in transglutaminase-induced differentiation of human prostate cancer cells.

  Amino acids 20111101

• Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism.

  Journal of hepatology 20111101

• Metabolic engineering for the production of prenylated polyphenols in transgenic legume plants using bacterial and plant prenyltransferases.

  Metabolic engineering 20111101

• Enantiomers of naringenin as pleiotropic, stereoselective inhibitors of cytochrome P450 isoforms.

  Chirality 20111101

• Naringenin is an inhibitor of human serum paraoxonase (PON1): an in vitro study.

  Journal of clinical laboratory analysis 20111101

• [Identification of the metabolites of Sinisan extract in rat plasma, urine, feces and bile after intragastric administration].

  Yao xue xue bao = Acta pharmaceutica Sinica 20111101

• A new languidulane diterpenoid from Salvia mexicana var. mexicana.

  Molecules (Basel, Switzerland) 20111021

• Biosynthesis of plant-specific phenylpropanoids by construction of an artificial biosynthetic pathway in Escherichia coli.

  Journal of industrial microbiology & biotechnology 20111001

• The flavonone naringenin inhibits chloride secretion in isolated colonic epithelia.

  European journal of pharmacology 20111001

• Over-expression of a grape stilbene synthase gene in tomato induces parthenocarpy and causes abnormal pollen development.

  Plant physiology and biochemistry : PPB 20111001

• A synthetic naringenin derivative, 5-hydroxy-7,4'-diacetyloxyflavanone-N-phenyl hydrazone (N101-43), induces apoptosis through up-regulation of Fas/FasL expression and inhibition of PI3K/Akt signaling pathways in non-small-cell lung cancer cells.

  Journal of agricultural and food chemistry 20110928

• Dietary flavones and flavonones display differential effects on aromatase (CYP19) transcription in the breast cancer cells MCF-7.

  Molecular and cellular endocrinology 20110915

• Evaluation of dual flow counter-current chromatography and intermittent counter-current extraction.

  Journal of chromatography. A 20110909

• Effects of flavonoids on prostaglandin E2 production and on COX-2 and mPGES-1 expressions in activated macrophages.

  Planta medica 20110901

• Study on naringenin-CTMAB-DNA system by resonance light scattering technique and its analytical application.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110901

• Antibacterial activity of naringin derivatives against pathogenic strains.

  Journal of applied microbiology 20110901

• Genome-scale metabolic network modeling results in minimal interventions that cooperatively force carbon flux towards malonyl-CoA.

  Metabolic engineering 20110901

• Quick development of an analytical enantioselective high performance liquid chromatography separation and preparative scale-up for the flavonoid Naringenin.

  Journal of chromatography. A 20110812

• Conjugates of 3α-methoxyserrat-14-en-21β-ol (PJ-1) and 3β-methoxyserrat-14-en-21β-ol (PJ-2) as cancer chemopreventive agents.

  European journal of medicinal chemistry 20110801

• LC-ESI-MS characterisation of phytoalexins induced in chickpea and pea tissues in response to a biotic elicitor of Hypnea musciformis (red algae).

  Natural product research 20110801

• Osteogenic effects of flavonoid aglycones from an osteoprotective fraction of Drynaria fortunei--an in vitro efficacy study.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20110715

• Optimization of a heterologous pathway for the production of flavonoids from glucose.

  Metabolic engineering 20110701

• The flavanone naringenin reduces the production of quorum sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1.

  Microbiology (Reading, England) 20110701

• Construction of a model to estimate the CYP3A inhibitory effect of grapefruit juice.

  Die Pharmazie 20110701

• Minor effects of the citrus flavonoids naringin, naringenin and quercetin, on the pharmacokinetics of doxorubicin in rats.

  Die Pharmazie 20110601

• Naringenin reduces lung metastasis in a breast cancer resection model.

  Protein & cell 20110601

• [Chemical constituents from herbs of Erigeron breviscapus].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110601

• A single-molecule study of the inhibition effect of Naringenin on transforming growth factor-β ligand-receptor binding.

  Chemical communications (Cambridge, England) 20110521

• Therapeutic efficacy of silymarin and naringenin in reducing arsenic-induced hepatic damage in young rats.

  Ecotoxicology and environmental safety 20110501

• C5-hydroxylation of liquiritigenin is catalyzed selectively by CYP1A2.

  Xenobiotica; the fate of foreign compounds in biological systems 20110501

• Naringenin attenuates mucous hypersecretion by modulating reactive oxygen species production and inhibiting NF-κB activity via EGFR-PI3K-Akt/ERK MAPKinase signaling in human airway epithelial cells.

  Molecular and cellular biochemistry 20110501

• Effect of flavonoids on basal and insulin-stimulated 2-deoxyglucose uptake in adipocytes.

  Molecular nutrition & food research 20110501

• Three 2-oxoglutarate-dependent dioxygenase activities of Equisetum arvense L. forming flavone and flavonol from (2S)-naringenin.

  Phytochemistry 20110501

• Properties of chalconaringenin and rutin isolated from cherry tomatoes.

  Journal of agricultural and food chemistry 20110413

• DNA-protective effects of quercetin or naringenin in alloxan-induced diabetic mice.

  European journal of pharmacology 20110410

• A stereospecific HPLC method and its application in determination of pharmacokinetics profile of two enantiomers of naringenin in rats.

  Journal of chromatographic science 20110401

• Flavonoids: precipitation kinetics and interaction with surfactant micelles.

  Journal of food science 20110401

• Dietary naringenin increases hepatic peroxisome proliferators-activated receptor α protein expression and decreases plasma triglyceride and adiposity in rats.

  European journal of nutrition 20110301

• Morelloflavone from Garcinia dulcis as a novel biflavonoid inhibitor of HMG-CoA reductase.

  Phytotherapy research : PTR 20110301

• Effects of flavonoids on glycosaminoglycan synthesis: implications for substrate reduction therapy in Sanfilippo disease and other mucopolysaccharidoses.

  Metabolic brain disease 20110301

• Constituents of the green tea seeds of Camellia sinensis.

  Natural product communications 20110301

• Naringenin up-regulates the expression of death receptor 5 and enhances TRAIL-induced apoptosis in human lung cancer A549 cells.

  Molecular nutrition & food research 20110201

• Screening of promoters from rhizosphere metagenomic DNA using a promoter-trap vector and flow cytometric cell sorting.

  Journal of basic microbiology 20110201

• [Study on intra-gastric floating beads of naringenin].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110201

• Citrus flavonoid represses Salmonella pathogenicity island 1 and motility in S. Typhimurium LT2.

  International journal of food microbiology 20110131

• Naringenin, a flavanone inhibits the proliferation of cerebrally implanted C6 glioma cells in rats.

  Chemico-biological interactions 20110115

• Identification of chemical constituents in extracts and rat plasma from Fructus Aurantii by UPLC-PDA-Q-TOF/MS.

  Phytochemical analysis : PCA 20110101

• Enhancement of naringenin bioavailability by complexation with hydroxypropyl-β-cyclodextrin. [corrected].

  PloS one 20110101

• Naringenin in combination with vitamins C and E potentially protects oxidative stress-mediated hepatic injury in cadmium-intoxicated rats.

  Journal of nutritional science and vitaminology 20110101

• Development and validation of a UHPLC method for the determination of flavonoids in red wine.

  Journal of AOAC International 20110101

• Direct semi-synthesis of the anticancer lead-drug protoapigenone from apigenin, and synthesis of further new cytotoxic protoflavone derivatives.

  PloS one 20110101

• Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives.

  Chemical research in toxicology 20101220

• Quantification of xanthohumol, isoxanthohumol, 8-prenylnaringenin, and 6-prenylnaringenin in hop extracts and derived capsules using secondary standards.

  Talanta 20101215

• Naringenin promote apoptosis in cerebrally implanted C6 glioma cells.

  Molecular and cellular biochemistry 20101201

• Targeting metabolic syndrome: candidate natural agents.

  Journal of diabetes 20101201

• Naringenin more effectively inhibits inducible nitric oxide synthase and cyclooxygenase-2 expression in macrophages than in microglia.

  Nutrition research (New York, N.Y.) 20101201

• Biotransformation of naringenin to eriodictyol by Saccharomyces cerevisiea functionally expressing flavonoid 3' hydroxylase.

  Natural product communications 20101201

• (+)-methyl jasmonate-induced bioformation of myricetin, quercetin and kaempferol in red raspberries.

  Journal of agricultural and food chemistry 20101124

• Elevated carbon dioxide increases contents of flavonoids and phenolic compounds, and antioxidant activities in Malaysian young ginger (Zingiber officinale Roscoe.) varieties.

  Molecules (Basel, Switzerland) 20101103

• Antifilarial activity in vitro and in vivo of some flavonoids tested against Brugia malayi.

  Acta tropica 20101101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Suppression of hepatic oxidative events and regulation of eNOS expression in the liver by naringenin in fructose-administered rats.

  European journal of pharmacology 20101025

• The effect of naringenin on the fate and disposition of deoxynivalenol in piglets.

  The Journal of veterinary medical science 20101001

• Involvement of monoaminergic system in the antidepressant-like effect of the flavonoid naringenin in mice.

  Progress in neuro-psychopharmacology & biological psychiatry 20101001

• Synthesis of vicenin-1 and 3, 6,8- and 8,6-di-C-beta-D-(glucopyranosyl-xylopyranosyl)-4',5,7-trihydroxyflavones using two direct C-glycosylations of naringenin and phloroacetophenone with unprotected D-glucose and D-xylose in aqueous solution as the key reactions.

  Carbohydrate research 20100903

• Suppression mechanisms of flavonoids on aryl hydrocarbon receptor-mediated signal transduction.

  Archives of biochemistry and biophysics 20100901

• A new chromone derivative from Berchemia lineata.

  Yao xue xue bao = Acta pharmaceutica Sinica 20100901

• Cochlospermum vitifolium induces vasorelaxant and antihypertensive effects mainly by activation of NO/cGMP signaling pathway.

  Journal of ethnopharmacology 20100809

• The nodC, nodG, and glgX genes of Rhizobium tropici strain PRF 81.

  Functional & integrative genomics 20100801

• Suppression of bacterial cell-cell signalling, biofilm formation and type III secretion system by citrus flavonoids.

  Journal of applied microbiology 20100801

• Quercetin and naringenin reduce abnormal development of mouse embryos produced by hydroxyurea.

  The Journal of pharmacy and pharmacology 20100801

• Synergistic and antagonistic interactions of phenolic compounds found in navel oranges.

  Journal of food science 20100801

• Flavonoid binding to human serum albumin.

  Biochemical and biophysical research communications 20100730

• Naringenin, a citrus flavonoid, increases muscle cell glucose uptake via AMPK.

  Biochemical and biophysical research communications 20100723

• Phenolic compounds as selective antineoplasic agents against multidrug-resistant human cancer cells.

  Planta medica 20100701

• LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis.

  Plant physiology 20100701

• [Evaluation of estrogen receptor Beta binding of pruni cortex and its constituents].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20100701

• Protective effects of silybin and analogues against X-ray radiation-induced damage.

  Acta biochimica et biophysica Sinica 20100701

• A novel regulatory mechanism of naringenin through inhibition of T lymphocyte function in contact hypersensitivity suppression.

  Biochemical and biophysical research communications 20100625

• Preparation and physicochemical properties of the complex of naringenin with hydroxypropyl-beta-cyclodextrin.

  Molecules (Basel, Switzerland) 20100618

• Absorption, conjugation and excretion of the flavanones, naringenin and hesperetin from alpha-rhamnosidase-treated orange juice in human subjects.

  The British journal of nutrition 20100601

• Identification of bioactive compounds from flowers of black elder (Sambucus nigra L.) that activate the human peroxisome proliferator-activated receptor (PPAR) gamma.

  Phytotherapy research : PTR 20100601

• Activation of transgenic estrogen receptor-beta by selected phytoestrogens in a stably transduced rat serotonergic cell line.

  The Journal of steroid biochemistry and molecular biology 20100601

• Apigenin and naringenin suppress colon carcinogenesis through the aberrant crypt stage in azoxymethane-treated rats.

  Experimental biology and medicine (Maywood, N.J.) 20100601

• [UPLC-Q-TOF-MS analysis of naringin and naringenin and its metabolites in rat plasma after intragastrical administration of alcohol extract of exocarpium Citri grandis].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100601

• [UPLC-Q-TOF/MS analysis of naringin and naringenin and its metabolites in rat urine and feces after intragastric administration of alcohol extract of Exocarpium Citri grandis].

  Yao xue xue bao = Acta pharmaceutica Sinica 20100601

• Antioxidant activity of oak (Quercus) leaves infusions against free radicals and their cardioprotective potential.

  Pakistan journal of biological sciences : PJBS 20100601

• Concentration and solubility of flavanones in orange beverages affect their bioavailability in humans.

  Journal of agricultural and food chemistry 20100526

• A randomized, double-blind, placebo-controlled, cross-over pilot study on the use of a standardized hop extract to alleviate menopausal discomforts.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20100501

• Preliminary investigation of naringenin hydroxylation with recombinant E. coli expressing plant flavonoid hydroxylation gene.

  Natural product communications 20100501

• Pharmacokinetic comparison in rats of six bioactive compounds between Da-Cheng-Qi decoction and its parent herbal medicines.

  Natural product communications 20100501

• Cytotoxic activities of several geranyl-substituted flavanones.

  Journal of natural products 20100423

• Pharmacokinetics-based elucidation on disparity in clinical effectiveness between varieties of Zhi Zhu Wan, a Traditional Chinese Medical formula.

  Journal of ethnopharmacology 20100421

• The citrus flavonoids hesperetin and naringenin block the lipolytic actions of TNF-alpha in mouse adipocytes.

  Biochemical and biophysical research communications 20100409

• Molecular characterization of flavonol synthase from poplar and its application to the synthesis of 3-O-methylkaempferol.

  Biotechnology letters 20100401

• Naringenin decreases progression of atherosclerosis by improving dyslipidemia in high-fat-fed low-density lipoprotein receptor-null mice.

  Arteriosclerosis, thrombosis, and vascular biology 20100401

• Relative bioavailability of the flavonoids quercetin, hesperetin and naringenin given simultaneously through diet.

  European journal of clinical nutrition 20100401

• Cadmium-induced hepatotoxicity in rats and the protective effect of naringenin.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20100301

• Dissolution rate and stability study of flavanone aglycones, naringenin and hesperetin, by drug delivery systems based on polyvinylpyrrolidone (PVP) nanodispersions.

  Drug development and industrial pharmacy 20100301

• Naringenin enhances insulin-stimulated tyrosine phosphorylation and improves the cellular actions of insulin in a dietary model of metabolic syndrome.

  European journal of nutrition 20100301

• Lipid-lowering and antioxidant effects of an ethyl acetate extract of fenugreek seeds in high-cholesterol-fed rats.

  Journal of agricultural and food chemistry 20100224

• Comparison of relative binding affinities to fish and mammalian estrogen receptors: the regulatory implications.

  Toxicology letters 20100215

• Biotransformation of naringin and naringenin by cultured Eucalyptus perriniana cells.

  Phytochemistry 20100201

• Structural activity relationship of flavonoids with estrogen-related receptor gamma.

  FEBS letters 20100104

• Prenylation has a compound specific effect on the estrogenicity of naringenin and genistein.

  The Journal of steroid biochemistry and molecular biology 20100101

• Disinfection by-products from halogenation of aqueous solutions of terpenoids.

  Water research 20100101

• Naringenin and 17beta-estradiol coadministration prevents hormone-induced human cancer cell growth.

  IUBMB life 20100101

• Naringenin inhibits neointimal hyperplasia following arterial reconstruction with interpositional vein graft.

  Annals of plastic surgery 20100101

• Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons.

  The FEBS journal 20100101

• Effects of unripe Citrus hassaku fruits extract and its flavanone glycosides on blood fluidity.

  Biological & pharmaceutical bulletin 20100101

• Separation/determination of flavonoids and ascorbic acid in rat serum and excrement by capillary electrophoresis with electrochemical detection.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20100101

• Identifying 8-hydroxynaringenin as a suicide substrate of mushroom tyrosinase.

  Journal of cosmetic science 20100101

• Transcriptional regulation of human and rat hepatic lipid metabolism by the grapefruit flavonoid naringenin: role of PPARalpha, PPARgamma and LXRalpha.

  PloS one 20100101

• Evaluation of the protective effects of quercetin, rutin, naringenin, resveratrol and trolox against idarubicin-induced DNA damage.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20100101

• Potent modification of inducible CYP1A1 expression by flavonoids.

  Biological & pharmaceutical bulletin 20100101

• [Activity of main enzymes of ammonium assimilation in Bradyrhizobium japonicum under the influence of plant flavonoid inductors].

  Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20100101

• Effect of naringenin on NaIO(3)-induced retinal pigment epithelium degeneration and laser-induced choroidal neovascularization in rats.

  International journal of ophthalmology 20100101

• Naringin inhibits matrix metalloproteinase-9 expression and AKT phosphorylation in tumor necrosis factor-alpha-induced vascular smooth muscle cells.

  Molecular nutrition & food research 20091201

• Production of genistein from naringenin using Escherichia coli containing isoflavone synthase-cytochrome P450 reductase fusion protein.

  Journal of microbiology and biotechnology 20091201

• Study of the chemical composition of the resinous exudate isolated from Heliotropium sclerocarpum and evaluation of the antioxidant properties of the phenolic compounds and the resin.

  Molecules (Basel, Switzerland) 20091112

• The efficient total synthesis of bis-glycosyl apigenin from naringenin: a greener way.

  Carbohydrate research 20091102

• Quercetin and naringenin transport across human intestinal Caco-2 cells.

  The Journal of pharmacy and pharmacology 20091101

• Metabolic engineering of Escherichia coli for the biological synthesis of 7-O-xylosyl naringenin.

  Molecules and cells 20091031

• Influence of ripeness and drying process on the polyphenols and tocopherols of Pistacia vera L.

  Molecules (Basel, Switzerland) 20091030

• Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistance.

  Diabetes 20091001

• Structure and antioxidant activity of brominated flavonols and flavanones.

  Journal of mass spectrometry : JMS 20091001

• A small functional intramolecular region of NodD was identified by mutation.

  Acta biochimica et biophysica Sinica 20091001

• Potential beneficial effect of naringenin on lipid peroxidation and antioxidant status in rats with ethanol-induced hepatotoxicity.

  The Journal of pharmacy and pharmacology 20091001

• Enzymatic properties of cytochrome P450 catalyzing 3'-hydroxylation of naringenin from the white-rot fungus Phanerochaete chrysosporium.

  Biochemical and biophysical research communications 20090911

• Directed evolution of the actinomycete cytochrome P450moxA (CYP105) for enhanced activity.

  Bioscience, biotechnology, and biochemistry 20090901

• Naringenin inhibits allergen-induced airway inflammation and airway responsiveness and inhibits NF-kappaB activity in a murine model of asthma.

  Canadian journal of physiology and pharmacology 20090901

• Fast analysis of prominent flavonoids in tomato using a monolithic column and isocratic HPLC.

  Journal of separation science 20090801

• Inhibitory mechanism of naringenin against carcinogenic acrylamide formation and nonenzymatic browning in Maillard model reactions.

  Chemical research in toxicology 20090801

• Expression of a Dianthus flavonoid glucosyltransferase in Saccharomyces cerevisiae for whole-cell biocatalysis.

  Journal of biotechnology 20090715

• Practical guidelines for characterization of O-diglycosyl flavonoid isomers by triple quadrupole MS and their applications for identification of some fruit juices flavonoids.

  Journal of mass spectrometry : JMS 20090701

• Statin-like principles of bergamot fruit (Citrus bergamia): isolation of 3-hydroxymethylglutaryl flavonoid glycosides.

  Journal of natural products 20090701

• Arabidopsis thaliana expresses a second functional flavonol synthase.

  FEBS letters 20090618

• Chemical analysis of the resinous exudate isolated from Heliotropium taltalense and evaluation of the antioxidant activity of the phenolics components and the resin in homogeneous and heterogeneous systems.

  Molecules (Basel, Switzerland) 20090602

• Phytochemical analysis of young fustic (Cotinus coggygria heartwood) and identification of isolated colourants in historical textiles.

  Analytical and bioanalytical chemistry 20090601

• Interactions of beta-carotene and flavonoids on the secretion of pro-inflammatory mediators in an in vitro system.

  Chemico-biological interactions 20090515

• Biological synthesis of 7-O-methyl Apigenin from naringenin using escherichia coli expressing two genes.

  Journal of microbiology and biotechnology 20090501

• Assessment of configurational and conformational properties of naringenin by vibrational circular dichroism.

  Chirality 20090401

• Naringenin inhibits human osteoclastogenesis and osteoclastic bone resorption.

  Journal of periodontal research 20090401

• Naringenin-loaded nanoparticles improve the physicochemical properties and the hepatoprotective effects of naringenin in orally-administered rats with CCl(4)-induced acute liver failure.

  Pharmaceutical research 20090401

• Grapefruit juice and its constituents augment colchicine intestinal absorption: potential hazardous interaction and the role of p-glycoprotein.

  Pharmaceutical research 20090401

• Naringenin enhances the anti-tumor effect of doxorubicin through selectively inhibiting the activity of multidrug resistance-associated proteins but not P-glycoprotein.

  Pharmaceutical research 20090401

• Identification of a Polygonum cuspidatum three-intron gene encoding a type III polyketide synthase producing both naringenin and p-hydroxybenzalacetone.

  Planta 20090401

• Screening of flavonoids as candidate antibiotics against Enterococcus faecalis.

  Journal of natural products 20090401

• Untargeted metabolite analysis of healthy and Huanglongbing-infected orange leaves by CE-DAD.

  Electrophoresis 20090401

• Naringenin: a potential immunomodulator for inhibiting lung fibrosis and metastasis.

  Cancer research 20090401

• The citrus flavanone naringenin inhibits inflammatory signalling in glial cells and protects against neuroinflammatory injury.

  Archives of biochemistry and biophysics 20090401

• AKR1C3 as a potential target for the inhibitory effect of dietary flavonoids.

  Chemico-biological interactions 20090316

• Naringenin-induced apoptosis is attenuated by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human leukemia U937 cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20090301

• Architectural phenotypes in the transparent testa mutants of Arabidopsis thaliana.

  Journal of experimental botany 20090301

• In vitro interactions with repeated grapefruit juice administration--to peel or not to peel?

  Planta medica 20090301

• Naringenin protects against cadmium-induced oxidative renal dysfunction in rats.

  Toxicology 20090204

• Simultaneous determination of the flavonoid aglycones diosmetin and hesperetin in human plasma and urine by a validated GC/MS method: in vivo metabolic reduction of diosmetin to hesperetin.

  Biomedical chromatography : BMC 20090201

• The citrus fruit flavonoid naringenin suppresses hepatic glucose production from Fao hepatoma cells.

  Molecular nutrition & food research 20090201

• Effect of flavonoids on daunorubicin-induced toxicity in H9c2 Cardiomyoblasts.

  Phytotherapy research : PTR 20090101

• Disposition of naringenin via glucuronidation pathway is affected by compensating efflux transporters of hydrophilic glucuronides.

  Molecular pharmaceutics 20090101

• Studies on modulation of DNA integrity in Fenton's system by phytochemicals.

  Mutation research 20081215

• Simultaneous determination of nine major active compounds in Dracocephalum rupestre by HPLC.

  Journal of pharmaceutical and biomedical analysis 20081215

• Establishment of a transgenic yeast screening system for estrogenicity and identification of the anti-estrogenic activity of malachite green.

  Journal of cellular biochemistry 20081215

• Influence of food polyphenols on aryl hydrocarbon receptor-signaling pathway estimated by in vitro bioassay.

  Phytochemistry 20081201

• Citrus fruit flavonoids influence on neutrophil apoptosis and oxidative metabolism.

  Phytotherapy research : PTR 20081201

• Naringenin induces apoptosis through downregulation of Akt and caspase-3 activation in human leukemia THP-1 cells.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081201

• Effects of dietary flavonoids on the transport of cimetidine via P-glycoprotein and cationic transporters in Caco-2 and LLC-PK1 cell models.

  Xenobiotica; the fate of foreign compounds in biological systems 20081201

• Naringenin and hesperetin induce growth arrest, apoptosis, and cytoplasmic fat deposit in human preadipocytes.

  Journal of agricultural and food chemistry 20081126

• Site-specific fluorescent labeling approaches for naringenin, an essential flavonone in plant nitrogen-fixation signaling pathways.

  The Journal of organic chemistry 20081107

• Time dependency of uterine effects of naringenin type phytoestrogens in vivo.

  Molecular and cellular endocrinology 20081106

• Antidiabetic and toxicological evaluations of naringenin in normoglycaemic and NIDDM rat models and its implications on extra-pancreatic glucose regulation.

  Diabetes, obesity & metabolism 20081101

• Enantiomeric separation of some flavanones using shinorhizobial linear octasaccharides in CE.

  Electrophoresis 20081101

• Concentrations of foliar quercetin in natural populations of white birch (Betula pubescens) increase with latitude.

  Journal of chemical ecology 20081101

• Synthesis, characterization, antioxidative activity and DNA binding properties of the copper(II), zinc(II), nickel(II) complexes with 1,2-Di(4'-iminonaringenin)ethane.

  Chemical & pharmaceutical bulletin 20081101

• Screening of natural phenolic compounds for potential to inhibit bacterial cell division protein FtsZ.

  Indian journal of experimental biology 20081101

• [Chemical constituents from the mycelia of Alternaria sp. YD-01].

  Yao xue xue bao = Acta pharmaceutica Sinica 20081101

• Modulatory effect of naringenin on N-methyl-N'-nitro-N-nitrosoguanidine- and saturated sodium chloride-induced gastric carcinogenesis in male Wistar rats.

  Clinical and experimental pharmacology & physiology 20081001

• Inhibition of apoB secretion from HepG2 cells by insulin is amplified by naringenin, independent of the insulin receptor.

  Journal of lipid research 20081001

• Naringenin and hesperetin, two flavonoids derived from Citrus aurantium up-regulate transcription of adiponectin.

  Phytotherapy research : PTR 20081001

• Trapping of phenylacetaldehyde as a key mechanism responsible for naringenin's inhibitory activity in mutagenic 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine formation.

  Chemical research in toxicology 20081001

• Impact of naringenin on glycoprotein levels in N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rats.

  Anti-cancer drugs 20081001

• Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers.

  Journal of agricultural and food chemistry 20080910

• Development of a food frequency questionnaire for the assessment of quercetin and naringenin intake.

  European journal of clinical nutrition 20080901

• In vitro observation of the molecular interaction between NodD and its inducer naringenin as monitored by fluorescence resonance energy transfer.

  Acta biochimica et biophysica Sinica 20080901

• Naringenin has anti-inflammatory properties in macrophage and ex vivo human whole-blood models.

  Journal of periodontal research 20080801

• [Protection against doxorubicin-induced oxidative damage in normal blood cells by naringenin].

  Zhongguo shi yan xue ye xue za zhi 20080801

• Effect of D256N and Y483D on propofol glucuronidation by human uridine 5'-diphosphate glucuronosyltransferase (UGT1A9).

  Basic & clinical pharmacology & toxicology 20080801

• [Studies on chemical constituents of Dendrobium crystallinum].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080801

• Simultaneous determination of naringenin and hesperetin in rats after oral administration of Da-Cheng-Qi decoction by high-performance liquid chromatography-tandem mass spectrometry.

  Biomedical chromatography : BMC 20080701

• Heterologous production of secondary metabolites as pharmaceuticals in Saccharomyces cerevisiae.

  Biotechnology letters 20080701

• Effect of grapefruit juice, naringin, naringenin, and bergamottin on the intestinal carrier-mediated transport of talinolol in rats.

  Journal of agricultural and food chemistry 20080625

• A grapefruit a day for patients infected with hepatitis C?

  Hepatology (Baltimore, Md.) 20080601

• Isolation of the MAO-inhibitor naringenin from Mentha aquatica L.

  Journal of ethnopharmacology 20080522

• Regulation of apoptosis by modified naringenin derivatives in human colorectal carcinoma RKO cells.

  Journal of cellular biochemistry 20080501

• The nutritional flavanone naringenin triggers antiestrogenic effects by regulating estrogen receptor alpha-palmitoylation.

  Endocrinology 20080501

• Apolipoprotein B-dependent hepatitis C virus secretion is inhibited by the grapefruit flavonoid naringenin.

  Hepatology (Baltimore, Md.) 20080501

• Grapefruit compound battles hepatitis C.

  JAMA 20080402

• Chemosensitivity determinants of irinotecan hydrochloride in hepatocellular carcinoma cell lines.

  Basic & clinical pharmacology & toxicology 20080401

• Expression of parsley flavone synthase I establishes the flavone biosynthetic pathway in Arabidopsis thaliana.

  Bioscience, biotechnology, and biochemistry 20080401

• [Relation of apoptosis of K562 cells induced by naringenin in vitro to enzyme activity changes of caspase-3 and caspase-8 and expression of FAS/FASL proteins].

  Zhongguo shi yan xue ye xue za zhi 20080401

• A new triterpenoid saponin from the fruits of Polygonum orientale.

  Yao xue xue bao = Acta pharmaceutica Sinica 20080401

• Antimetastatic potentials of flavones on oral cancer cell via an inhibition of matrix-degrading proteases.

  Archives of oral biology 20080301

• Pharmacokinetics of selected chiral flavonoids: hesperetin, naringenin and eriodictyol in rats and their content in fruit juices.

  Biopharmaceutics & drug disposition 20080301

• Distinct effects of naringenin and hesperetin on nitric oxide production from endothelial cells.

  Journal of agricultural and food chemistry 20080213

• Effect of adding extracted hesperetin, naringenin and pectin on egg cholesterol, serum traits and antioxidant activity in laying hens.

  Archives of animal nutrition 20080201

• Naringenin reduces tumor size and weight lost in N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rats.

  Nutrition research (New York, N.Y.) 20080201

• Characterization of flavone synthase I from rice.

  BMB reports 20080131

• Apigenin inhibits HGF-promoted invasive growth and metastasis involving blocking PI3K/Akt pathway and beta 4 integrin function in MDA-MB-231 breast cancer cells.

  Toxicology and applied pharmacology 20080115

• The expectorant activity of naringenin.

  Pulmonary pharmacology & therapeutics 20080101

• The additive effects of the active component of grapefruit juice (naringenin) and antiarrhythmic drugs on HERG inhibition.

  Cardiology 20080101

• Naringenin protects HaCaT human keratinocytes against UVB-induced apoptosis and enhances the removal of cyclobutane pyrimidine dimers from the genome.

  Photochemistry and photobiology 20080101

• [Chemical constituents from Spatholobus sinensis].

  Yao xue xue bao = Acta pharmaceutica Sinica 20080101

• Inhibition of oral carcinogenesis by citrus flavonoids.

  Nutrition and cancer 20080101

• Suppressive effects of the flavonoids quercetin and luteolin on the accumulation of lipid rafts after signal transduction via receptors.

  Immunopharmacology and immunotoxicology 20080101

• Cellular mechanisms underlying the laxative effect of flavonol naringenin on rat constipation model.

  PloS one 20080101

• Antagonistic interactions between the flavonoids hesperetin and naringenin and beta-lactam antibiotics against Staphylococcus aureus.

  British journal of biomedical science 20080101

• Evaluation of proinflammatory cytokine pathway inhibitors for p38 MAPK inhibitory potential.

  Journal of medicinal chemistry 20071213

• Antimicrobial activity of flavonoids extracted from bergamot (Citrus bergamia Risso) peel, a byproduct of the essential oil industry.

  Journal of applied microbiology 20071201

• Induction of apoptotic cell death by synthetic naringenin derivatives in human lung epithelial carcinoma A549 cells.

  Biological & pharmaceutical bulletin 20071201

• Inhibition effect of flavonoids on monocarboxylate transporter 1 (MCT1) in Caco-2 cells.

  The Journal of pharmacy and pharmacology 20071101

• Grapefruit juice-drug interactions: Grapefruit juice and its components inhibit P-glycoprotein (ABCB1) mediated transport of talinolol in Caco-2 cells.

  Journal of pharmaceutical sciences 20071001

• Effects of adlay (Coix lachryma-jobi L. var. ma-yuen Stapf.) hull extracts on the secretion of progesterone and estradiol in vivo and in vitro.

  Experimental biology and medicine (Maywood, N.J.) 20071001

• [Studies on chemical constituents from Rhizoma Heterosmilacis Japonicae].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20071001

• A novel molecular assay to discriminate transcriptional effects caused by xenoestrogens.

  Molecular and cellular endocrinology 20070930

• Flavonoid glycosides are not transported by the human Na+/glucose transporter when expressed in Xenopus laevis oocytes, but effectively inhibit electrogenic glucose uptake.

  The Journal of pharmacology and experimental therapeutics 20070801

• Inhibitory activities of dietary phenolic compounds on heterocyclic amine formation in both chemical model system and beef patties.

  Molecular nutrition & food research 20070801

• Flavanone plasma pharmacokinetics from blood orange juice in human subjects.

  The British journal of nutrition 20070701

• Absorption and pharmacokinetics of grapefruit flavanones in beagles.

  The British journal of nutrition 20070701

• Esterase inhibition by grapefruit juice flavonoids leading to a new drug interaction.

  Drug metabolism and disposition: the biological fate of chemicals 20070701

• Infrared and DNA-binding on ultraviolet and fluorescence spectra of new copper and zinc complexes with a naringenin Schiff-base ligand.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070601

• Flavonoid biosynthesis in barley primary leaves requires the presence of the vacuole and controls the activity of vacuolar flavonoid transport.

  Plant physiology 20070501

• Enantioseparation of some chiral flavanones using microbial cyclic beta-(1-->3),(1-->6)-glucans as novel chiral additives in capillary electrophoresis.

  Carbohydrate research 20070409

• Pharmacokinetics of the citrus flavanone aglycones hesperetin and naringenin after single oral administration in human subjects.

  European journal of clinical nutrition 20070401

• In vivo metabolic effects of naringenin in the ethanol consuming rat and the effect of naringenin on adipocytes in vitro.

  Journal of animal physiology and animal nutrition 20070401

• Resolution of diastereomeric flavonoid (1S)-(-)-camphanic acid esters via reversed-phase HPLC.

  Phytochemistry 20070401

• Rapid qualitative and quantitative analyses of flavanone aglycones in Fructus aurantii by HPLC ion-trap MS.

  Journal of separation science 20070401

• Effect of the citrus flavanone naringenin on oxidative stress in rats.

  Journal of agricultural and food chemistry 20070321

• Identification of kaempferol as an inhibitor of cigarette smoke-induced activation of the aryl hydrocarbon receptor and cell transformation.

  Carcinogenesis 20070301

• Differential effect of dietary antioxidant classes (carotenoids, polyphenols, vitamins C and E) on lutein absorption.

  The British journal of nutrition 20070301

• Hypoglycemic, vasorelaxant and hepatoprotective effects of Cochlospermum vitifolium (Willd.) Sprengel: a potential agent for the treatment of metabolic syndrome.

  Journal of ethnopharmacology 20070212

• Flavonoids modulate monocarboxylate transporter-1-mediated transport of gamma-hydroxybutyrate in vitro and in vivo.

  Drug metabolism and disposition: the biological fate of chemicals 20070201

• Enhancement of transglutaminase activity and polyamine depletion in B16-F10 melanoma cells by flavonoids naringenin and hesperitin correlate to reduction of the in vivo metastatic potential.

  Amino acids 20070101

• One-pot synthesis of genistein from tyrosine by coincubation of genetically engineered Escherichia coli and Saccharomyces cerevisiae cells.

  Applied microbiology and biotechnology 20070101

• Hypocholesterolemic and antioxidative effects of naringenin and its two metabolites in high-cholesterol fed rats.

  Translational research : the journal of laboratory and clinical medicine 20070101

• Synthesis, characterization and antioxidant activity of naringenin Schiff base and its Cu(II), Ni(II), Zn(II) complexes.

  Chemical & pharmaceutical bulletin 20070101

• Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages.

  Mediators of inflammation 20070101

• (+/-)-Naringenin as large conductance Ca(2+)-activated K+ (BKCa) channel opener in vascular smooth muscle cells.

  British journal of pharmacology 20061201

• Comparison of the effects of selected chalcones, dihydrochalcones and some cyclic flavonoids on mitochondrial outer membrane determined by fluorescence spectroscopy.

  Journal of biochemical and biophysical methods 20061130

• ApoO, a novel apolipoprotein, is an original glycoprotein up-regulated by diabetes in human heart.

  The Journal of biological chemistry 20061124

• Flavanone metabolism in healthy and tumor-bearing rats.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20061101

• Phytoestrogens as inhibitors of the human progesterone metabolizing enzyme AKR1C1.

  Molecular and cellular endocrinology 20061019

• Naringenin-induced apoptosis via activation of NF-kappaB and necrosis involving the loss of ATP in human promyeloleukemia HL-60 cells.

  Toxicology letters 20061010

• Enhanced therapeutic potential of naringenin-phospholipid complex in rats.

  The Journal of pharmacy and pharmacology 20060901

• Identification of isomeric flavonoid glucuronides in urine and plasma by metal complexation and LC-ESI-MS/MS.

  Journal of mass spectrometry : JMS 20060701

• Naringenin is a novel inhibitor of Dictyostelium cell proliferation and cell migration.

  Biochemical and biophysical research communications 20060623

• Total synthesis of three naturally occurring 6,8-di-C-glycosylflavonoids: phloretin, naringenin, and apigenin bis-C-beta-D-glucosides.

  Carbohydrate research 20060612

• Stimulation of melanogenesis by the citrus flavonoid naringenin in mouse B16 melanoma cells.

  Bioscience, biotechnology, and biochemistry 20060601

• Activity and mRNA levels of enzymes involved in hepatic fatty acid oxidation in mice fed citrus flavonoids.

  Nutrition (Burbank, Los Angeles County, Calif.) 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Influence of naringenin on oxytetracycline mediated oxidative damage in rat liver.

  Basic & clinical pharmacology & toxicology 20060501

• Synthesis, characterization, cytotoxic activities, and DNA-binding properties of the La(III) complex with Naringenin Schiff-base.

  Bioorganic & medicinal chemistry 20060315

• Anthocyanidin synthase from Gerbera hybrida catalyzes the conversion of (+)-catechin to cyanidin and a novel procyanidin.

  FEBS letters 20060306

• A novel polar surface polysaccharide from Rhizobium leguminosarum binds host plant lectin.

  Molecular microbiology 20060301

• The chemical and biologic profile of a red clover (Trifolium pratense L.) phase II clinical extract.

  Journal of alternative and complementary medicine (New York, N.Y.) 20060301

• A rapid LC/MS/MS quantitation assay for naringin and its two metabolites in rats plasma.

  Journal of pharmaceutical and biomedical analysis 20060213

• Regiospecific flavonoid 7-O-methylation with Streptomyces avermitilis O-methyltransferase expressed in Escherichia coli.

  Journal of agricultural and food chemistry 20060208

• The citrus flavonoid naringenin stimulates DNA repair in prostate cancer cells.

  The Journal of nutritional biochemistry 20060201

• Protective effect of selected flavonoids on in vitro daunorubicin-induced cardiotoxicity.

  Phytotherapy research : PTR 20060201

• Quantitative and qualitative analysis of flavonoid markers in Frucus aurantii of different geographical origin by capillary electrophoresis with electrochemical detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060118

• LC/MS/MS quantitation assay for pharmacokinetics of naringenin and double peaks phenomenon in rats plasma.

  International journal of pharmaceutics 20060113

• Variation of flavonoids and furanocoumarins in grapefruit juices: a potential source of variability in grapefruit juice-drug interaction studies.

  Journal of agricultural and food chemistry 20060111

• Inhibition of intestinal and renal Na+-glucose cotransporter by naringenin.

  The international journal of biochemistry & cell biology 20060101

• Smad3 specific inhibitor, naringenin, decreases the expression of extracellular matrix induced by TGF-beta1 in cultured rat hepatic stellate cells.

  Pharmaceutical research 20060101

• Variations in content of active ingredients causing drug interactions in grapefruit juice products sold in California.

  Drug metabolism and drug interactions 20060101

• [Flavonoids as effective protectors of urease from ultrasonic inactivation in solutions].

  Bioorganicheskaia khimiia 20060101

• Impact of naringenin on oxytetracycline-mediated oxidative damage in kidney of rats.

  Renal failure 20060101

• Effect of naringenin on intracerebroventricular streptozotocin-induced cognitive deficits in rat: a behavioral analysis.

  Pharmacology 20060101

• Naringin time-dependently lowers hepatic cholesterol biosynthesis and plasma cholesterol in rats fed high-fat and high-cholesterol diet.

  Journal of medicinal food 20060101

• Abatement by naringenin of doxorubicin-induced cardiac toxicity in rats.

  Journal of the Egyptian National Cancer Institute 20051201

• Disposition of selected flavonoids in fruit tissues of various tomato (lycopersicon esculentum mill.) Genotypes.

  Journal of agricultural and food chemistry 20051130

• Oxidation of dietary polyphenolics by hydroperoxidase activity of lipoxygenase.

  Journal of agricultural and food chemistry 20051116

• Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease.

  Free radical research 20051001

• Negative regulation of beta-catenin/Tcf signaling by naringenin in AGS gastric cancer cell.

  Biochemical and biophysical research communications 20050930

• Regiospecific methylation of naringenin to ponciretin by soybean O-methyltransferase expressed in Escherichia coli.

  Journal of biotechnology 20050923

• Structural and mechanistic studies on anthocyanidin synthase catalysed oxidation of flavanone substrates: the effect of C-2 stereochemistry on product selectivity and mechanism.

  Organic & biomolecular chemistry 20050907

• Efficient production of (2S)-flavanones by Escherichia coli containing an artificial biosynthetic gene cluster.

  Applied microbiology and biotechnology 20050901

• Stereospecific high-performance liquid chromatographic analysis of naringenin in urine.

  Journal of pharmaceutical and biomedical analysis 20050901

• Phytoestrogens induce differential estrogen receptor alpha- or Beta-mediated responses in transfected breast cancer cells.

  Experimental biology and medicine (Maywood, N.J.) 20050901

• Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5).

  The FEBS journal 20050901

• The effects of naringin and naringenin on endotoxin-induced uveitis in rats.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20050801

• Dihydrostilbene derivatives from Glycyrrhiza glabra leaves.

  Journal of natural products 20050701

• Inhibition of microsomal triglyceride transfer protein expression and apolipoprotein B100 secretion by the citrus flavonoid naringenin and by insulin involves activation of the mitogen-activated protein kinase pathway in hepatocytes.

  Diabetes 20050601

• Inhibition of cardiac HERG channels by grapefruit flavonoid naringenin: implications for the influence of dietary compounds on cardiac repolarisation.

  Naunyn-Schmiedeberg's archives of pharmacology 20050601

• High-performance liquid chromatographic separation and chiroptical properties of the enantiomers of naringenin and other flavanones.

  Journal of chromatography. A 20050527

• (-)Epigallocatechin gallate and quercetin enhance survival signaling in response to oxidant-induced human endothelial apoptosis.

  The Journal of nutrition 20050401

• Synergistic antitumor effect of polyphenolic components of water soluble derivative of propolis against Ehrlich ascites tumour.

  Biological & pharmaceutical bulletin 20050401

• Naringenin attenuates cisplatin nephrotoxicity in rats.

  Life sciences 20050318

• Human fecal water content of phenolics: the extent of colonic exposure to aromatic compounds.

  Free radical biology & medicine 20050315

• Inhibitory effects of naringenin on tumor growth in human cancer cell lines and sarcoma S-180-implanted mice.

  Biological & pharmaceutical bulletin 20050301

• QTc prolongation by grapefruit juice and its potential pharmacological basis: HERG channel blockade by flavonoids.

  Circulation 20050222

• Anti-inflammatory effect of heme oxygenase 1: glycosylation and nitric oxide inhibition in macrophages.

  Journal of cellular physiology 20050201

• Electrochemical detection of xenoestrogenic and antiestrogenic compounds using a yeast two-hybrid-17-beta-estradiol system.

  Bioelectrochemistry (Amsterdam, Netherlands) 20050201

• Implication of cyclic nucleotide phosphodiesterase inhibition in the vasorelaxant activity of the citrus-fruits flavonoid (+/-)-naringenin.

  Planta medica 20050201

• Naringenin-type flavonoids show different estrogenic effects in mammalian and teleost test systems.

  Biochemical and biophysical research communications 20050128

• A simple biomimetic synthesis of dl-chamaejasmine, a unique 3,3'-biflavanone.

  Organic letters 20050120

• Nobiletin, a citrus flavonoid isolated from tangerines, selectively inhibits class A scavenger receptor-mediated metabolism of acetylated LDL by mouse macrophages.

  Atherosclerosis 20050101

• The effects of dietary naringenin supplementation on physiological changes in molar crestal alveolar bone-cemento-enamel junction distance in young rats.

  Journal of medicinal food 20050101

• The effects of dietary phytoestrogens on aromatase activity in human endometrial stromal cells.

  Reproduction, nutrition, development 20050101

• Non-empirical assignment of the absolute configuration of (-)-naringenin, by coupling the exciton analysis of the circular dichroism spectrum and the ab initio calculation of the optical rotatory power.

  Organic & biomolecular chemistry 20041221

• Effects of grapefruit juice on the multidrug transporter P-glycoprotein in the human proximal tubular cell line HK-2.

  Life sciences 20041203

• Effect of domestic cooking on human bioavailability of naringenin, chlorogenic acid, lycopene and beta-carotene in cherry tomatoes.

  European journal of nutrition 20041201

• The differential tissue distribution of the citrus flavanone naringenin following gastric instillation.

  Free radical research 20041201

• Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells.

  Toxicological sciences : an official journal of the Society of Toxicology 20041101

• Combined effect of pH and polysorbates with cyclodextrins on solubilization of naringenin.

  Journal of pharmaceutical and biomedical analysis 20041029

• The pig caecum model: a suitable tool to study the intestinal metabolism of flavonoids.

  Molecular nutrition & food research 20040901

• Suppression of CYP1A1 expression by naringenin in murine Hepa-1c1c7 cells.

  Archives of pharmacal research 20040801

• Mechanisms of naringenin-induced apoptotic cascade in cancer cells: involvement of estrogen receptor alpha and beta signalling.

  IUBMB life 20040801

• First bacterial chalcone isomerase isolated from Eubacterium ramulus.

  Archives of microbiology 20040601

• Toward the prediction of the activity of antioxidants: experimental and theoretical study of the gas-phase acidities of flavonoids.

  Journal of the American Society for Mass Spectrometry 20040601

• Dietary polyphenols increase paraoxonase 1 gene expression by an aryl hydrocarbon receptor-dependent mechanism.

  Molecular and cellular biology 20040601

• Toxicity and cell cycle effects of synthetic 8-prenylnaringenin and derivatives in human cells.

  Pharmacology 20040501

• Naringenin inhibits glucose uptake in MCF-7 breast cancer cells: a mechanism for impaired cellular proliferation.

  Breast cancer research and treatment 20040501

• Exploring recombinant flavonoid biosynthesis in metabolically engineered Escherichia coli.

  Chembiochem : a European journal of chemical biology 20040402

• New metabolic pathways for flavanones catalyzed by rat liver microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20040401

• Effect of antioxidant flavanone, naringenin, from Citrus junoson neuroprotection.

  Journal of agricultural and food chemistry 20040324

• Significance of C-terminal sequence elements for Petunia flavanone 3beta-hydroxylase activity.

  FEBS letters 20040312

• Validated high-performance liquid chromatographic method utilizing solid-phase extraction for the simultaneous determination of naringenin and hesperetin in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040305

• Flavonoid permeability across an in situ model of the blood-brain barrier.

  Free radical biology & medicine 20040301

• Nutritional flavonoids modulate estrogen receptor alpha signaling.

  IUBMB life 20040301

• Lethal and teratogenic effects of naringenin evaluated by means of an amphibian embryo toxicity test (AMPHITOX).

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040201

• Biphasic effects of the flavonoids quercetin and naringenin on the metabolic activation of 2-amino-3,5-dimethylimidazo[4,5-f]quinoline by Salmonella typhimurium TA1538 co-expressing human cytochrome P450 1A2, NADPH-cytochrome P450 reductase, and cytochrome b5.

  Mutation research 20040112

• Differential and special properties of the major human UGT1-encoded gastrointestinal UDP-glucuronosyltransferases enhance potential to control chemical uptake.

  The Journal of biological chemistry 20040109

• Inhibition of guinea pig intestinal peristalsis by the flavonoids quercetin, naringenin, apigenin and genistein.

  Pharmacology 20040101

• TRANSPARENT TESTA 19 is involved in the accumulation of both anthocyanins and proanthocyanidins in Arabidopsis.

  The Plant journal : for cell and molecular biology 20040101

• The flavonoid naringenin inhibits dimethylnitrosamine-induced liver damage in rats.

  Biological & pharmaceutical bulletin 20040101

• The phytoalexin-inducible multidrug efflux pump AcrAB contributes to virulence in the fire blight pathogen, Erwinia amylovora.

  Molecular plant-microbe interactions : MPMI 20040101

• The citrus-derived flavonoid naringenin exerts uterotrophic effects in female mice at human relevant doses.

  Basic & clinical pharmacology & toxicology 20040101

• Naringenin from Citrus junos has an inhibitory effect on acetylcholinesterase and a mitigating effect on amnesia.

  Dementia and geriatric cognitive disorders 20040101

• Drug-drug interactions evaluated by a highly active reconstituted native human cytochrome P4503A4 and human NADPH-cytochrome P450 reductase system.

  Arzneimittel-Forschung 20040101

• Cryptosporidium parvum: effect of multi-drug reversing agents on the expression and function of ATP-binding cassette transporters.

  Experimental parasitology 20040101

• Hepatolipidemic effects of naringenin in high cornstarch- versus high coconut oil-fed rats.

  Journal of medicinal food 20040101

• Influence of naringenin on the activity of enzymes participating in steroidogenesis in male rats.

  Roczniki Akademii Medycznej w Bialymstoku (1995) 20040101

• Inhibition of hydrogen peroxide-induced endothelial apoptosis by 2',4',7-trihydroxyflavanone, a flavonoid form.

  Journal of medicinal food 20040101

• The inhibitory effects of flavonoids and antiestrogens on the Glut1 glucose transporter in human erythrocytes.

  Chemico-biological interactions 20031215

• Screening of the inhibitory effect of vegetable constituents on the aryl hydrocarbon receptor-mediated activity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

  Biological & pharmaceutical bulletin 20031201

• Analysis of propolis from the continental and Adriatic regions of Croatia.

  Acta pharmaceutica (Zagreb, Croatia) 20031201

• Naringenin derivatives as anti-atherogenic agents.

  Bioorganic & medicinal chemistry letters 20031117

• Characterization of leachianone G 2'-dimethylallyltransferase, a novel prenyl side-chain elongation enzyme for the formation of the lavandulyl group of sophoraflavanone G in Sophora flavescens Ait. cell suspension cultures.

  Plant physiology 20031101

• Formation of novel flavonoids in apple (Malusxdomestica) treated with the 2-oxoglutarate-dependent dioxygenase inhibitor prohexadione-Ca.

  Phytochemistry 20031001

• Rutinoside at C7 attenuates the apoptosis-inducing activity of flavonoids.

  Biochemical pharmacology 20031001

• Inhibition of net HepG2 cell apolipoprotein B secretion by the citrus flavonoid naringenin involves activation of phosphatidylinositol 3-kinase, independent of insulin receptor substrate-1 phosphorylation.

  Diabetes 20031001

• Flavanone 3-hydroxylase expression in Citrus paradisi and Petunia hybrida seedlings.

  Phytochemistry 20030901

• Antifungal flavanones and prenylated hydroquinones from Piper crassinervium Kunth.

  Phytochemistry 20030901

• Antiandrogenic activity of the phytoestrogens naringenin, 6-(1,1-dimethylallyl)naringenin and 8-prenylnaringenin.

  Planta medica 20030901

• Naringin and naringenin inhibit nitrite-induced methemoglobin formation.

  Die Pharmazie 20030801

• Simultaneous detection of the antioxidant and pro-oxidant activity of dietary polyphenolics in a peroxidase system.

  Free radical research 20030701

• Cell-specific activation of aflatoxin B1 correlates with presence of some cytochrome P450 enzymes in olfactory and respiratory tissues in horse.

  Research in veterinary science 20030601

• Pro-oxidative properties of flavonoids in human lymphocytes.

  Bioscience, biotechnology, and biochemistry 20030601

• Naringenin inhibits phosphoinositide 3-kinase activity and glucose uptake in 3T3-L1 adipocytes.

  Biochemical and biophysical research communications 20030530

• Interaction between flavonoids and the blood-brain barrier: in vitro studies.

  Journal of neurochemistry 20030401

• Muscanone: a 3-O-(1', 8', 14'-trimethylhexadecanyl)naringenin from Commiphora wightii.

  Phytochemistry 20030401

• [Studies on chemical constitutes of Phellinus igniarius].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030401

• The variable effect on proliferation of a colon cancer cell line by the citrus fruit flavonoid Naringenin.

  Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20030301

• [Study on chemical constituents in rhizome of Smilax perfoliate].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030301

• Hepatocyte apoB-containing lipoprotein secretion is decreased by the grapefruit flavonoid, naringenin, via inhibition of MTP-mediated microsomal triglyceride accumulation.

  Biochemistry 20030211

• Naringenin 7-O-cetyl ether as inhibitor of HMG-CoA reductase and modulator of plasma and hepatic lipids in high cholesterol-fed rats.

  Bioorganic & medicinal chemistry 20030206

• Bioavailability in humans of the flavanones hesperidin and narirutin after the ingestion of two doses of orange juice.

  European journal of clinical nutrition 20030201

• Flavonol synthase from Citrus unshiu is a bifunctional dioxygenase.

  Phytochemistry 20030201

• Bioflavonoid stimulation of glutathione transport by the 190-kDa multidrug resistance protein 1 (MRP1).

  Drug metabolism and disposition: the biological fate of chemicals 20030101

• Anti-Sindbis activity of flavanones hesperetin and naringenin.

  Biological & pharmaceutical bulletin 20030101

• In vitro inhibition of simvastatin metabolism, a HMG-CoA reductase inhibitor in human and rat liver by bergamottin, a component of grapefruit juice.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030101

• Flavonoids and nitric oxide synthase.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20021201

• Stimulation of alkaline phosphatase activity in Ishikawa cells induced by various phytoestrogens and synthetic estrogens.

  The Journal of steroid biochemistry and molecular biology 20021201

• Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9.

  Drug metabolism and disposition: the biological fate of chemicals 20021101

• Molecular characterization of root-specific chalcone synthases from Cassia alata.

  Planta 20021101

• High-flavonol tomatoes resulting from the heterologous expression of the maize transcription factor genes LC and C1.

  The Plant cell 20021001

• Plasma concentrations of the flavonoids hesperetin, naringenin and quercetin in human subjects following their habitual diets, and diets high or low in fruit and vegetables.

  European journal of clinical nutrition 20020901

• Inhibition of hepatocyte apoB secretion by naringenin: enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters.

  Journal of lipid research 20020901

• Effect of exogenous flavonoids on nodulation of pea (Pisum sativum L.).

  Journal of experimental botany 20020801

• Supplementation of naringenin and its synthetic derivative alters antioxidant enzyme activities of erythrocyte and liver in high cholesterol-fed rats.

  Bioorganic & medicinal chemistry 20020701

• In vitro properties of a recombinant flavonol synthase from Arabidopsis thaliana.

  Phytochemistry 20020701

• Relationship between estrogen receptor-binding and estrogenic activities of environmental estrogens and suppression by flavonoids.

  Bioscience, biotechnology, and biochemistry 20020701

• Phenolic glycosides from Viscum angulatum.

  Journal of natural products 20020501

• Estrogenic activity of the phytoestrogens naringenin, 6-(1,1-dimethylallyl)naringenin and 8-prenylnaringenin.

  Planta medica 20020501

• Effects of grapefruit juice and smoking on verapamil concentrations in steady state.

  European journal of clinical pharmacology 20020401

• Comparison of metabolic pharmacokinetics of naringin and naringenin in rabbits.

  Life sciences 20020215

• The action of dietary phytochemicals quercetin, catechin, resveratrol and naringenin on estrogen-mediated gene expression.

  Life sciences 20020215

• Reaction mechanism of chalcone isomerase. pH dependence, diffusion control, and product binding differences.

  The Journal of biological chemistry 20020111

• Quantification of the production of dihydrokaempferol by flavanone 3-hydroxytransferase using capillary electrophoresis.

  Phytochemical analysis : PCA 20020101

• Effects of plant-derived phenols on rat liver cytochrome P450 2B1 activity.

  Anticancer research 20020101

• Preincubation of Mesorhizobium ciceri with flavonoids improves its nodule occupancy.

  Folia microbiologica 20020101

• Comparison of in vitro hepatic models for the prediction of metabolic interaction between simvastatin and naringenin.

  European journal of drug metabolism and pharmacokinetics 20020101

• Structure-guided programming of polyketide chain-length determination in chalcone synthase.

  Biochemistry 20011211

• Effect of P-glycoprotein modulators on the pharmacokinetics of camptothecin using microdialysis.

  British journal of pharmacology 20011101

• Cloning of parsley flavone synthase I.

  Phytochemistry 20010901

• The use of a high-volume screening procedure to assess the effects of dietary flavonoids on human cyp1a1 expression.

  Drug metabolism and disposition: the biological fate of chemicals 20010801

• Effect of honey and sugars on the metabolism and disposition of naringin in rabbits.

  Planta medica 20010801

• Anti-atherogenic effect of citrus flavonoids, naringin and naringenin, associated with hepatic ACAT and aortic VCAM-1 and MCP-1 in high cholesterol-fed rabbits.

  Biochemical and biophysical research communications 20010615

• Flavonoids act as negative regulators of auxin transport in vivo in arabidopsis.

  Plant physiology 20010601

• Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids.

  Molecular pharmacology 20010501

• Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP.

  Journal of lipid research 20010501

• 17beta-Estradiol but not the phytoestrogen naringenin attenuates aortic cholesterol accumulation in WHHL rabbits.

  Journal of lipid research 20010501

• Differential effects of flavonoids on 3T3-L1 adipogenesis and lipolysis.

  American journal of physiology. Cell physiology 20010401

• Enzymatic characterization and interspecies difference of phenol sulfotransferases, ST1A forms.

  Drug metabolism and disposition: the biological fate of chemicals 20010301

• Characterization of 2-[[4-[[2-(1H-tetrazol-5-ylmethyl)phenyl]methoxy]methyl]quinoline N-glucuronidation by in vitro and in vivo approaches.

  Drug metabolism and disposition: the biological fate of chemicals 20010301

• Peroxidative metabolism of apigenin and naringenin versus luteolin and quercetin: glutathione oxidation and conjugation.

  Free radical biology & medicine 20010215

• Antimicrobial activity of prenylflavanones.

  In vivo (Athens, Greece) 20010101

• Differential estrogen receptor binding of estrogenic substances: a species comparison.

  The Journal of steroid biochemistry and molecular biology 20001115

• Flavonoids inhibit cell growth and induce apoptosis in B16 melanoma 4A5 cells.

  Bioscience, biotechnology, and biochemistry 20000901

• Ligand structure-dependent differences in activation of estrogen receptor alpha in human HepG2 liver and U2 osteogenic cancer cell lines.

  Molecular and cellular endocrinology 20000425

• Estrogen receptor activation via activation function 2 predicts agonism of xenoestrogens in normal and neoplastic cells of the uterine myometrium.

  Cancer research 19990701

• Suppression of nitric oxide synthase and the down-regulation of the activation of NFkappaB in macrophages by resveratrol.

  British journal of pharmacology 19990201

• Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.

  Endocrinology 19981001

• Molecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis study.

  Environmental health perspectives 19980201

• Cloning and expression of a rat liver phenobarbital-inducible UDP-glucuronosyltransferase (2B12) with specificity for monoterpenoid alcohols.

  Archives of biochemistry and biophysics 19951001

• Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates.

  Drug metabolism and disposition: the biological fate of chemicals 19940101