681136-29-8 | JNJ-1661010

Packsize	Purity	Availability	Price	Discounted Price
5mg	≥98%	in stock	$94.00	$66.00
10mg	≥98%	in stock	$142.00	$99.00
25mg	≥98%	in stock	$255.00	$179.00
50mg	≥98%	in stock	$462.00	$324.00

Description

• Catalog Number: AB77750
• Chemical Name: JNJ-1661010
• CAS Number: 681136-29-8
• Molecular Formula: C19H19N5OS
• Molecular Weight: 365.4521
• MDL Number: MFCD00209157
• SMILES: O=C(N1CCN(CC1)c1snc(n1)c1ccccc1)Nc1ccccc1

Computed Properties

• Complexity: 459
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 26
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3
• XLogP3: 3.5

Literature

• The discovery and development of inhibitors of fatty acid amide hydrolase (FAAH).

  Bioorganic & medicinal chemistry letters 20110815

• Identification of potent, noncovalent fatty acid amide hydrolase (FAAH) inhibitors.

  Bioorganic & medicinal chemistry letters 20110415

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Fatty acid amide hydrolase inhibitors. Surprising selectivity of chiral azetidine ureas.

  Bioorganic & medicinal chemistry letters 20090801

• Biochemical and biological properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase.

  Anesthesia and analgesia 20090101

• Dynamic regulation of the endocannabinoid system: implications for analgesia.

  Molecular pain 20090101

• Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amide hydrolase.

  Bioorganic & medicinal chemistry letters 20080901

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501