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Effects of lipoic acid on lipolysis in 3T3-L1 adipocytes.
Journal of lipid research 20121101
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Pharmacologic agents elevating cAMP prevent arginase II expression and proliferation of pulmonary artery smooth muscle cells.
American journal of respiratory cell and molecular biology 20120801
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Gap junction-mediated communications regulate chromatin remodeling during bovine oocyte growth and differentiation through cAMP-dependent mechanism(s).
Biology of reproduction 20111201
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Acylated and unacylated ghrelin attenuate isoproterenol-induced lipolysis in isolated rat visceral adipocytes through activation of phosphoinositide 3-kinase γ and phosphodiesterase 3B.
Biochimica et biophysica acta 20110601
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Neurite outgrowth mediated by translation elongation factor eEF1A1: a target for antiplatelet agent cilostazol.
PloS one 20110101
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Simulated physiological oocyte maturation (SPOM): a novel in vitro maturation system that substantially improves embryo yield and pregnancy outcomes.
Human reproduction (Oxford, England) 20101201
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Anagrelide represses GATA-1 and FOG-1 expression without interfering with thrombopoietin receptor signal transduction.
Journal of thrombosis and haemostasis : JTH 20101001
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Function of cardiac beta1- and beta2-adrenoceptors of newborn piglets: role of phosphodiesterases PDE3 and PDE4.
European journal of pharmacology 20100725
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A role of phosphodiesterase-3B pathway in mediating leptin action on proopiomelanocortin and neurotensin neurons in the hypothalamus.
Neuroscience letters 20100719
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PDE5A suppression of acute beta-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation.
Basic research in cardiology 20100501
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Decreased expression and activity of cAMP phosphodiesterases in cardiac hypertrophy and its impact on beta-adrenergic cAMP signals.
Circulation research 20091009
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Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Nature chemical biology 20091001
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Design, synthesis and pharmacological evaluation of 6-hydroxy-4-methylquinolin-2(1H)-one derivatives as inotropic agents.
Journal of enzyme inhibition and medicinal chemistry 20090801
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Effects of the cAMP-elevating agents cilostamide, cilostazol and forskolin on the phosphorylation of Akt and GSK-3beta in platelets.
Thrombosis and haemostasis 20090801
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Cilostamide produces hyperpolarization associated with K(ATP) channel activation, but does not augment endothelium-derived hyperpolarization in rat mesenteric arteries.
Clinical and experimental pharmacology & physiology 20090701
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Phosphodiesterases PDE3 and PDE4 jointly control the inotropic effects but not chronotropic effects of (-)-CGP12177 despite PDE4-evoked sinoatrial bradycardia in rat atrium.
Naunyn-Schmiedeberg's archives of pharmacology 20090401
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Inotropy and L-type Ca2+ current, activated by beta1- and beta2-adrenoceptors, are differently controlled by phosphodiesterases 3 and 4 in rat heart.
British journal of pharmacology 20090101
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Ontogenic changes of the control by phosphodiesterase-3 and -4 of 5-HT responses in porcine heart and relevance to human atrial 5-HT(4) receptors.
British journal of pharmacology 20090101
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Phosphodiesterase 3 is present in rabbit and human erythrocytes and its inhibition potentiates iloprost-induced increases in cAMP.
American journal of physiology. Heart and circulatory physiology 20080801
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Effect of temporary nuclear arrest by phosphodiesterase 3-inhibitor on morphological and functional aspects of in vitro matured mouse oocytes.
Molecular reproduction and development 20080601
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Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases.
Circulation research 20080509
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Effects of cilostamide and forskolin on the meiotic resumption and embryonic development of immature human oocytes.
Human reproduction (Oxford, England) 20080301
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Phosphodiesterase-4 blunts inotropism and arrhythmias but not sinoatrial tachycardia of (-)-adrenaline mediated through mouse cardiac beta(1)-adrenoceptors.
British journal of pharmacology 20080201
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Numerous distinct PKA-, or EPAC-based, signalling complexes allow selective phosphodiesterase 3 and phosphodiesterase 4 coordination of cell adhesion.
Cellular signalling 20071201
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The effects of both noradrenaline and CGP12177, mediated through human beta1 -adrenoceptors, are reduced by PDE3 in human atrium but PDE4 in CHO cells.
Naunyn-Schmiedeberg's archives of pharmacology 20070401
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Cilostamide potentiates more the positive inotropic effects of (-)-adrenaline through beta(2)-adrenoceptors than the effects of (-)-noradrenaline through beta (1)-adrenoceptors in human atrial myocardium.
Naunyn-Schmiedeberg's archives of pharmacology 20061201
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Phosphodiesterase PDE3 blunts the positive inotropic and cyclic AMP enhancing effects of CGP12177 but not of noradrenaline in rat ventricle.
British journal of pharmacology 20060101
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New insight into the role of phosphodiesterase 3A in porcine oocyte maturation.
BMC developmental biology 20060101
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Effects of long-term in vitro exposure to phosphodiesterase type-3 inhibitors on follicle and oocyte development.
Reproduction (Cambridge, England) 20050801
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The phosphodiesterase 3 inhibitor cilostamide enhances inotropic responses to glucagon but not to dobutamine in rat ventricular myocardium.
European journal of pharmacology 20050411
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Fundamental significance of specific phosphodiesterases in the control of spontaneous meiotic resumption in porcine oocytes.
Molecular reproduction and development 20050301
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Vascular endothelial cell cyclic nucleotide phosphodiesterases and regulated cell migration: implications in angiogenesis.
Molecular pharmacology 20050101
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Mouse oocyte meiotic resumption and polar body extrusion in vitro are differentially influenced by FSH, epidermal growth factor and meiosis-activating sterol.
Human reproduction (Oxford, England) 20041201
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The action mechanism of zinc(II) complexes with insulinomimetic activity in rat adipocytes.
Life sciences 20040625
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Identification of purine inhibitors of phosphodiesterase 7 (PDE7).
Bioorganic & medicinal chemistry letters 20040607
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Impaired activation of phosphatidylinositol 3-kinase by leptin is a novel mechanism of hepatic leptin resistance in diet-induced obesity.
The Journal of biological chemistry 20040521
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Augmentation of lipolysis in adipocytes from fed rats, but not from starved rats, by inhibition of rolipram-sensitive phosphodiesterase 4.
Archives of biochemistry and biophysics 20040501
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Benzyl vinylogous amide substituted aryldihydropyridazinones and aryldimethylpyrazolones as potent and selective PDE3B inhibitors.
Bioorganic & medicinal chemistry letters 20031117
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Synthesis and pharmacological characterization of functionalized 2-pyridones structurally related to the cardiotonic agent milrinone.
Bioorganic & medicinal chemistry 20031103
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The role of tryptophan 1072 in human PDE3B inhibitor binding.
Biochemical and biophysical research communications 20030808
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Phosphodiesterase 3 activity is reduced in dog lung following pacing-induced heart failure.
American journal of physiology. Lung cellular and molecular physiology 20030501
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Phosphodiesterase 3 inhibitors selectively block the spontaneous resumption of meiosis by macaque oocytes in vitro.
Human reproduction (Oxford, England) 20020801
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Changes in phosphodiesterase activity in the developing rat submandibular gland.
Archives of oral biology 20020801
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Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
The Journal of biological chemistry 20020419
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Differential effects of specific phosphodiesterase isoenzyme inhibitors on bovine oocyte meiotic maturation.
Developmental biology 20020415
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Altered phosphodiesterase 3-mediated cAMP hydrolysis contributes to a hypermotile phenotype in obese JCR:LA-cp rat aortic vascular smooth muscle cells: implications for diabetes-associated cardiovascular disease.
Diabetes 20020401
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Inhibition of PDE3B augments PDE4 inhibitor-induced apoptosis in a subset of patients with chronic lymphocytic leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 20020201
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Mechanism of intracellular calcium ([Ca2+]i) inhibition of lipolysis in human adipocytes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011101
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Inhibitors of phosphodiesterase isoforms III or IV suppress islet-cell nitric oxide production.
Laboratory investigation; a journal of technical methods and pathology 20010801
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Cyclic GMP regulation of the L-type Ca(2+) channel current in human atrial myocytes.
The Journal of physiology 20010601
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Characterization of an in vivo hormonally regulated phosphodiesterase 3 (PDE3) associated with a liver Golgi-endosomal fraction.
Archives of biochemistry and biophysics 20010301
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Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity.
Biochemical pharmacology 20000215
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Inhibitors of cyclic AMP phosphodiesterase. 1. Analogues of cilostamide and anagrelide.
Journal of medicinal chemistry 19870201
