710-11-2 | 2-Oxo-4-phenylbutyric acid

Packsize	Purity	Availability	Price	Discounted Price
5g	97%	in stock	$8.00	$6.00
25g	97%	in stock	$27.00	$19.00
500g	98%	in stock	$449.00	$315.00

Description

• Catalog Number: AI55319
• Chemical Name: 2-Oxo-4-phenylbutyric acid
• CAS Number: 710-11-2
• Molecular Formula: C10H10O3
• Molecular Weight: 178.1846
• MDL Number: MFCD00969471
• SMILES: O=C(C(=O)O)CCc1ccccc1

Computed Properties

• Complexity: 192
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 4
• XLogP3: 1.6

Literature

• Direct asymmetric hydrogenation of 2-oxo-4-arylbut-3-enoic acids.

  The Journal of organic chemistry 20100903

• Simultaneous synthesis of 2-phenylethanol and L-homophenylalanine using aromatic transaminase with yeast Ehrlich pathway.

  Biotechnology and bioengineering 20090401

• Asymmetrically simultaneous synthesis of L-homophenylalanine and N6-protected-2-oxo-6-amino-hexanoic acid by engineered Escherichia coli aspartate aminotransferase.

  Biotechnology progress 20090101

• Synthesis of enantiopure (S)-2-hydroxyphenylbutanoic acid using novel hydroxy acid dehydrogenase from Enterobacter sp. BK2K.

  Biotechnology progress 20070101

• Biotransformation of R-2-hydroxy-4-phenylbutyric acid by D-lactate dehydrogenase and Candida boidinii cells containing formate dehydrogenase coimmobilized in a fibrous bed bioreactor.

  Biotechnology and bioengineering 20051020

• Asymmetrical synthesis of L-homophenylalanine using engineered Escherichia coli aspartate aminotransferase.

  Biotechnology progress 20050101

• Discovery of alpha,gamma-diketo acids as potent selective and reversible inhibitors of hepatitis C virus NS5b RNA-dependent RNA polymerase.

  Journal of medicinal chemistry 20040101

• Asymmetric synthesis of L-homophenylalanine by equilibrium-shift using recombinant aromatic L-amino acid transaminase.

  Biotechnology and bioengineering 20030720

• Use of a pharmacophore model to discover a new class of influenza endonuclease inhibitors.

  Journal of medicinal chemistry 20030327

• Inhibition of cap (m7GpppXm)-dependent endonuclease of influenza virus by 4-substituted 2,4-dioxobutanoic acid compounds.

  Antimicrobial agents and chemotherapy 19941201