721-90-4 | H-Phe-gly-oh

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$17.00	$12.00
250mg	95%	in stock	$41.00	$29.00
1g	95%	in stock	$120.00	$84.00

Description

• Catalog Number: AH16195
• Chemical Name: H-Phe-gly-oh
• CAS Number: 721-90-4
• Molecular Formula: C11H14N2O3
• Molecular Weight: 222.2405
• MDL Number: MFCD00021728
• SMILES: N[C@H](C(=O)NCC(=O)O)Cc1ccccc1

Computed Properties

• Complexity: 250
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 5
• XLogP3: -2.5

Literature

• Prohormone-substrate peptide sequence recognition by peptidylglycine α-amidating monooxygenase and its reflection in increased glycolate inhibitor potency.

  Bioorganic & medicinal chemistry letters 20121201

• Hydrogen exchange equilibria in thiols.

  Chemical research in toxicology 20120917

• Modulation of fibrillation of hIAPP core fragments by chemical modification of the peptide backbone.

  Biochimica et biophysica acta 20120201

• Fragmental modeling of hPepT2 and analysis of its binding features by docking studies and pharmacophore mapping.

  Bioorganic & medicinal chemistry 20110801

• Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

  Nature chemical biology 20090101

• Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding.

  Journal of medicinal chemistry 20060615

• Molecular mechanism of the inhibition of cytochrome c aggregation by Phe-Gly.

  Archives of biochemistry and biophysics 20050301

• Intrinsic folding of small peptide chains: spectroscopic evidence for the formation of beta-turns in the gas phase.

  Journal of the American Chemical Society 20050119

• Phe-Gly dipeptidomimetics designed for the di-/tripeptide transporters PEPT1 and PEPT2: synthesis and biological investigations.

  Journal of medicinal chemistry 20040212

• Translocation of beta-catenin into the nucleus independent of interactions with FG-rich nucleoporins.

  Experimental cell research 20031101

• Enhanced transdermal delivery of phenylalanyl-glycine by chemical modification with various fatty acids.

  International journal of pharmaceutics 20030102

• Enhanced permeability of phenylalanyl-glycine (Phe-Gly) across the intestinal membranes by chemical modification with various fatty acids.

  Drug metabolism and pharmacokinetics 20030101

• Diastereoselective reduction of a chiral N-Boc-protected delta-amino-alpha,beta-unsaturated gamma-keto ester Phe-Gly dipeptidomimetic.

  The Journal of organic chemistry 20021227

• In vivo nephrotoxic action of an isomeric mixture of S-(1-phenyl-2-hydroxyethyl)glutathione and S-(2-phenyl-2-hydroxyethyl)glutathione in Fischer-344 rats.

  Toxicology 19910325