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Determination of aniracetam's main metabolite, N-anisoyl-GABA, in human plasma by LC-MS/MS and its application to a pharmacokinetic study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120515
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Clinical efficacy of aniracetam, either as monotherapy or combined with cholinesterase inhibitors, in patients with cognitive impairment: a comparative open study.
CNS neuroscience & therapeutics 20120401
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Impulsive behaviour induced by both NMDA receptor antagonism and GABAA receptor activation in rat ventromedial prefrontal cortex.
Psychopharmacology 20120101
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Systematic review on the efficacy and safety of herbal medicines for vascular dementia.
Evidence-based complementary and alternative medicine : eCAM 20120101
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[Effects of moxibustion on the expressions of hippocampal VEGF, flt-1, bFGF, and bFGF-r in vascular dementia rats].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20120101
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NMDA receptors and fear extinction: implications for cognitive behavioral therapy.
Dialogues in clinical neuroscience 20111201
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Development and validation of a liquid chromatographic method for the simultaneous determination of aniracetam and its related substances in the bulk drug and a tablet formulation.
Journal of pharmaceutical and biomedical analysis 20111101
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Role of endocannabinoid and glutamatergic systems in DOI-induced head-twitch response in mice.
Pharmacology, biochemistry, and behavior 20110701
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Substituted benzoxazinones as potent positive allosteric AMPA receptor modulators: part II.
Bioorganic & medicinal chemistry letters 20110701
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Benzoxazinones as potent positive allosteric AMPA receptor modulators: part I.
Bioorganic & medicinal chemistry letters 20110701
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From toxins targeting ligand gated ion channels to therapeutic molecules.
Toxins 20110301
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Lipid rafts control P2X3 receptor distribution and function in trigeminal sensory neurons of a transgenic migraine mouse model.
Molecular pain 20110101
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Subnanogram determination of aniracetam in pharmaceutical preparations and biofluids by flow injection analysis with chemiluminescence detection based on its enhancement of the myoglobin-luminol reaction.
Journal of AOAC International 20110101
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Acetylcholine and memory-enhancing activity of Ficus racemosa bark.
Pharmacognosy research 20110101
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How right is the righting reflex? The risk of false positives in neuroprotection studies using behavioral measures to certify forebrain ischemia.
Neurological research 20101101
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Positive allosteric modulators of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor.
Journal of medicinal chemistry 20101028
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Retinohypothalamic tract synapses in the rat suprachiasmatic nucleus demonstrate short-term synaptic plasticity.
Journal of neurophysiology 20100501
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Piracetam defines a new binding site for allosteric modulators of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors.
Journal of medicinal chemistry 20100311
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Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders.
Drugs 20100212
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[Effect of modified huanglian wendan decoction in treating senile patients with mild cognitive impairment of turbid-phlegm blocking orifice syndrome].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20100101
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Activation of AMPA receptors in the suprachiasmatic nucleus phase-shifts the mouse circadian clock in vivo and in vitro.
PloS one 20100101
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Herbal therapy: a new pathway for the treatment of Alzheimer's disease.
Alzheimer's research & therapy 20100101
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Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors.
Bioorganic & medicinal chemistry letters 20091201
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[Influence of aniracetam on the learning ability, memory ability and the expression of BCL-2 of hippocampal in vascular dementia model rats].
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20090501
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Aniracetam and DNQX affect the acquisition of rapid tolerance to ethanol in mice.
Pharmacology, biochemistry, and behavior 20090301
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Content determination of aniracetam in aniracetam inclusion complex by HPLC.
Artificial cells, blood substitutes, and immobilization biotechnology 20090101
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Relative roles of different mechanisms of depression at the mouse endbulb of Held.
Journal of neurophysiology 20080501
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Aniracetam reversed learning and memory deficits following prenatal ethanol exposure by modulating functions of synaptic AMPA receptors.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080401
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Participation of hippocampal ionotropic glutamate receptors in histamine H(1) antagonist-induced memory deficit in rats.
Psychopharmacology 20080301
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[Effects of Goutengsan on model of Alzheimer dementia in rats by AlCl3].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080301
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Ameliorating effects of preadolescent aniracetam treatment on prenatal ethanol-induced impairment in AMPA receptor activity.
Neurobiology of disease 20080101
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[A randomized, controlled, double-blind trial of Huannao Yicong capsule in senile patients with mild cognitive impairment].
Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20080101
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Pharmacokinetics and bioequivalence study of aniracetam after single-dose administration in healthy Chinese male volunteers.
Arzneimittel-Forschung 20080101
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Sensitive and selective liquid chromatography-tandem mass spectrometry method for the quantification of aniracetam in human plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071015
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Progress update: Pharmacological treatment of Alzheimer's disease.
Neuropsychiatric disease and treatment 20071001
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[Clinical study on a randomized, double-blind control of Shenwu gelatin capsule in treatment of mild cognitive impairment].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070901
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Identification of a putative binding site for 5-alkyl-benzothiadiazides in the AMPA receptor dimer interface.
Journal of molecular graphics & modelling 20070701
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Postnatal aniracetam treatment improves prenatal ethanol induced attenuation of AMPA receptor-mediated synaptic transmission.
Neurobiology of disease 20070601
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Pharmacology of ampakine modulators: from AMPA receptors to synapses and behavior.
Current drug targets 20070501
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AMPA receptor potentiators: application for depression and Parkinson's disease.
Current drug targets 20070501
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The ampakine CX546 restores the prepulse inhibition and latent inhibition deficits in mGluR5-deficient mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070401
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Aniracetam restores the effects of amyloid-beta protein or ageing on membrane fluidity and intracellular calcium concentration in mice synaptosomes.
Journal of neural transmission (Vienna, Austria : 1996) 20070101
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Enantiomeric impurity determination of levetiracetam using capillary electrochromatography.
Journal of separation science 20061201
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In search of novel AMPA potentiators.
Recent patents on CNS drug discovery 20061101
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Aniracetam attenuates H2O2-induced deficiency of neuron viability, mitochondria potential and hippocampal long-term potentiation of mice in vitro.
Neuroscience bulletin 20060901
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Delayed, post-injury treatment with aniracetam improves cognitive performance after traumatic brain injury in rats.
Journal of neurotrauma 20060801
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Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
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The alkaloid alstonine: a review of its pharmacological properties.
Evidence-based complementary and alternative medicine : eCAM 20060301
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Brahmi rasayana improves learning and memory in mice.
Evidence-based complementary and alternative medicine : eCAM 20060301
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Regulation of glutamatergic signalling by PACAP in the mammalian suprachiasmatic nucleus.
BMC neuroscience 20060101
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Nardostachys jatamansi improves learning and memory in mice.
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Cognitive aging in zebrafish.
PloS one 20060101
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Mechanism of positive allosteric modulators acting on AMPA receptors.
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Nootropic agents enhance the recruitment of fast GABAA inhibition in rat neocortex.
Cerebral cortex (New York, N.Y. : 1991) 20050701
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Effects of propofol on recombinant AMPA receptor channels.
European journal of pharmacology 20050321
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Effect of aniracetam on phosphatidylinositol transfer protein alpha in cytosolic and plasma membrane fractions of astrocytes subjected to simulated ischemia in vitro.
Pharmacological reports : PR 20050101
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Mild cognitive impairment: animal models.
Dialogues in clinical neuroscience 20041201
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Interactions of allosteric modulators of AMPA/kainate receptors on spreading depression in the chicken retina.
Brain research 20041029
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Nootropic nefiracetam inhibits proconvulsant action of peripheral-type benzodiazepines in epileptic mutant EL mice.
Annals of the New York Academy of Sciences 20041001
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AMPA protects cultured neurons against glutamate excitotoxicity through a phosphatidylinositol 3-kinase-dependent activation in extracellular signal-regulated kinase to upregulate BDNF gene expression.
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Erk1/2 and Akt kinases are involved in the protective effect of aniracetam in astrocytes subjected to simulated ischemia in vitro.
European journal of pharmacology 20040628
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Piracetam and TRH analogues antagonise inhibition by barbiturates, diazepam, melatonin and galanin of human erythrocyte D-glucose transport.
British journal of pharmacology 20040601
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AMPA receptor potentiators for the treatment of CNS disorders.
Current drug targets. CNS and neurological disorders 20040601
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The cognition-enhancer nefiracetam inhibits both necrosis and apoptosis in retinal ischemic models in vitro and in vivo.
The Journal of pharmacology and experimental therapeutics 20040401
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Multiple molecular determinants for allosteric modulation of alternatively spliced AMPA receptors.
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2-pyrrolidinone induces a long-lasting facilitation of hippocampal synaptic transmission by enhancing alpha7 ACh receptor responses via a PKC pathway.
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The mechanism of action of aniracetam at synaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors: indirect and direct effects on desensitization.
Molecular pharmacology 20030801
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Sialic acid 9-O-acetylesterase catalyzes the hydrolyzing reaction from alacepril to deacetylalacepril.
Pharmaceutical research 20030801
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Facilitation of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor transmission in the suprachiasmatic nucleus by aniracetam enhances photic responses of the biological clock in rodents.
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Multiple sclerosis and glutamate.
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Effects of aniracetam on extracellular levels of transmitter amino acids in the hippocampus of the conscious gerbils: an intracranial microdialysis study.
Neuroscience letters 20030327
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Dialogues in clinical neuroscience 20021201
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Nonopioid and neuropathy-specific analgesic action of the nootropic drug nefiracetam in mice.
The Journal of pharmacology and experimental therapeutics 20021001
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Aniracetam attenuates apoptosis of astrocytes subjected to simulated ischemia in vitro.
Neurotoxicology 20020901
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A desensitization-selective potentiator of AMPA-type glutamate receptors.
British journal of pharmacology 20020801
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DM235 (sunifiram): a novel nootropic with potential as a cognitive enhancer.
Naunyn-Schmiedeberg's archives of pharmacology 20020601
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Cholinergic and dopaminergic mechanisms involved in the recovery of circadian anticipation by aniracetam in aged rats.
Pharmacology, biochemistry, and behavior 20020501
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Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
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Antidepressant activity of memory-enhancing drugs in the reduction of submissive behavior model.
European journal of pharmacology 20020405
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Aniracetam enhances glutamatergic transmission in the prefrontal cortex of stroke-prone spontaneously hypertensive rats.
Neuroscience letters 20020308
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The cognition-enhancer nefiracetam is protective in BDNF-independent neuronal cell death under the serum-free condition.
Neurochemistry international 20020201
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The aniracetam metabolite 2-pyrrolidinone induces a long-term enhancement in AMPA receptor responses via a CaMKII pathway.
Brain research. Molecular brain research 20020131
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Aniracetam improves contextual fear conditioning and increases hippocampal gamma-PKC activation in DBA/2J mice.
Hippocampus 20020101
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Aniracetam: its novel therapeutic potential in cerebral dysfunctional disorders based on recent pharmacological discoveries.
CNS drug reviews 20020101
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Negative allosteric modulation of AMPA-preferring receptors by the selective isomer GYKI 53784 (LY303070), a specific non-competitive AMPA antagonist.
CNS drug reviews 20020101
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Maturation of synaptic transmission at end-bulb synapses of the cochlear nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20011201
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Antidepressant-like effects of aniracetam in aged rats and its mode of action.
Psychopharmacology 20011101
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Aniracetam enhances cortical dopamine and serotonin release via cholinergic and glutamatergic mechanisms in SHRSP.
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The AMPA receptor allosteric potentiator PEPA ameliorates post-ischemic memory impairment.
Neuroreport 20010917
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Pharmacological effects of AMPA receptor potentiators LY392098 and LY404187 on rat neuronal AMPA receptors in vitro.
Neuropharmacology 20010601
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LY392098, a novel AMPA receptor potentiator: electrophysiological studies in prefrontal cortical neurons.
Neuropharmacology 20010601
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Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism.
European journal of pharmacology 20010518
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Member of the Ampakine class of memory enhancers prolongs the single channel open time of reconstituted AMPA receptors.
Synapse (New York, N.Y.) 20010501
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Positive allosteric modulators of AMPA receptors reduce proton-induced receptor desensitization in rat hippocampal neurons.
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Site-specific activation of dopamine and serotonin transmission by aniracetam in the mesocorticolimbic pathway of rats.
Brain research 20010406
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Nootropic drug modulation of neuronal nicotinic acetylcholine receptors in rat cortical neurons.
Molecular pharmacology 20010401
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Minimizing synaptic depression by control of release probability.
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Effects of intrahippocampal aniracetam treatment on Y-maze avoidance learning performance and behavioral long-term potentiation in dentate gyrus in rat.
Neuroscience letters 20010209
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Can nootropic drugs be effective against the impact of ethanol teratogenicity on cognitive performance?
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20010201
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Autonomic consequences of brainstem infarction.
Autonomic neuroscience : basic & clinical 20010114
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Neuroscience 20010101
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Aniracetam restores motivation reduced by satiation in a choice reaction task in aged rats.
Pharmacology, biochemistry, and behavior 20010101
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Efficacy of acetylcholinesterase inhibitors versus nootropics in Alzheimer's disease: a retrospective, longitudinal study.
The Journal of international medical research 20010101
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European journal of pharmacology 20000804
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Hydrolytic profile for ester- or amide-linkage by carboxylesterases pI 5.3 and 4.5 from human liver.
Biological & pharmaceutical bulletin 19970801
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Effects of D-cycloserine and aniracetam on spatial learning in rats with entorhinal cortex lesions.
Pharmacology, biochemistry, and behavior 19970101
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Effects of DM-9384, a pyrrolidone derivative, on alcohol- and chlordiazepoxide-induced amnesia in mice.
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Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam.
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Japanese journal of pharmacology 19890501
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Effects of aniracetam on one-trial passive avoidance tests and cholinergic neurons in discrete brain regions of rats.
Archives internationales de pharmacodynamie et de therapie 19890101
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The hyperventilation-induced ischaemia model in human neuropharmacology: neurophysiological and psychometric studies of aniracetam and 3-OH aniracetam.
European journal of clinical pharmacology 19890101
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Interactions between oxiracetam, aniracetam and scopolamine on behavior and brain acetylcholine.
Pharmacology, biochemistry, and behavior 19870701
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Effects of the novel compound aniracetam (Ro 13-5057) upon impaired learning and memory in rodents.
Psychopharmacology 19820101
