7341-96-0 | Propiolamide

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$15.00	$11.00
5g	95%	in stock	$42.00	$30.00
10g	95%	in stock	$81.00	$57.00
25g	95%	in stock	$202.00	$142.00

Description

• Catalog Number: AB46931
• Chemical Name: Propiolamide
• CAS Number: 7341-96-0
• Molecular Formula: C3H3NO
• Molecular Weight: 69.0620
• MDL Number: MFCD04035573
• SMILES: NC(=O)C#C
• NSC Number: 520954

Computed Properties

• Complexity: 86.3
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 5
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• XLogP3: -0.4

Literature

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  Acta crystallographica. Section E, Structure reports online 20120401

• N-[2-(N-Cyclo-hexyl-carbamo-yl)propan-2-yl]-N-(2-iodo-phen-yl)prop-2-ynamide.

  Acta crystallographica. Section E, Structure reports online 20120201

• Propargylaminyl 3α-hy-droxy-11-oxo-18β-olean-12-en-29-oate.

  Acta crystallographica. Section E, Structure reports online 20111101

• Irreversible Nek2 kinase inhibitors with cellular activity.

  Journal of medicinal chemistry 20110623

• A novel Zn-catalyzed hydroamination of propargylamides: a general synthesis of di- and tri-substituted imidazoles.

  Chemical communications (Cambridge, England) 20110221

• Introducing structural flexibility into porphyrin-DNA zipper arrays.

  Organic & biomolecular chemistry 20110207

• Novel irreversible epidermal growth factor receptor inhibitors by chemical modulation of the cysteine-trap portion.

  Journal of medicinal chemistry 20100311

• Cyclization of propargylic amides: mild access to oxazole derivatives.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20100118

• Highly selective fluorescent probe for Au3+ based on cyclization of propargylamide.

  Chemical communications (Cambridge, England) 20091214

• Optimisation of chemical protein cleavage for erythropoietin semi-synthesis using native chemical ligation.

  Organic & biomolecular chemistry 20081107

• Gold- and silver-mediated cycloisomerizations of N-propargylamides.

  Organic letters 20081002

• Intramolecular Pd(II)-catalyzed cyclization of propargylamides: straightforward synthesis of 5-oxazolecarbaldehydes.

  The Journal of organic chemistry 20080620

• Synthesis and characterization of polyacetylene with side-chain thiophene functionality.

  International journal of molecular sciences 20080301

• Amphiphilic poly(N-propargylamide) with galactose and lauryloyl groups: synthesis and properties.

  Macromolecular bioscience 20061208

• Reversal of regioselectivity and enhancement of rates of nitrile oxide cycloadditions through transient attachment of dipolarophiles to cyclodextrins.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20061115

• N-propargylamides via the asymmetric michael addition of B-alkynyl-10-TMS-9- borabicyclo[3.3.2]decanes to N-acylimines.

  Organic letters 20060720

• Asymmetric synthesis of propargylamides via 3,3'-disubstituted binaphthol-modified alkynylboronates.

  Organic letters 20060105

• Copper-catalyzed coupling of imines, acid chlorides, and alkynes: a multicomponent route to propargylamides.

  Organic letters 20040401

• Efficient and general synthesis of 5-(alkoxycarbonyl)methylene-3-oxazolines by palladium-catalyzed oxidative carbonylation of prop-2-ynylamides.

  The Journal of organic chemistry 20020628

• Approach toward the total synthesis of griseoviridin: formation of thioethynyl and thiovinyl ether-containing nine-membered lactones through a thioalkynylation-macrolactonization-hydrostannylation sequence.

  The Journal of organic chemistry 20020628

• Multi-component assembly of the bicyclic core associated with the tRNA synthetase inhibitors SB-203207 and SB-203208. Application to the synthesis of biologically active analogues.

  Chemical communications (Cambridge, England) 20011107

• Preparation of 2,5-disubstituted oxazoles from N-propargylamides.

  Organic letters 20010809