75191-78-5 | 1,4-Dihydroquinazolin-2-amine

Availability
Typically In Stock

Description

• Catalog Number: AI55959
• Chemical Name: 1,4-Dihydroquinazolin-2-amine
• CAS Number: 75191-78-5
• Molecular Formula: C8H9N3
• Molecular Weight: 147.1772
• MDL Number: MFCD19207111
• SMILES: NC1=NCc2c(N1)cccc2

Computed Properties

• Complexity: 176
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 2
• XLogP3: 0.2

Literature

• 2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead.

  Journal of medicinal chemistry 20070906