752187-80-7 | Taprenepag

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$22.00	$15.00
5mg	98%	in stock	$50.00	$35.00
10mg	98%	in stock	$61.00	$43.00

Description

• Catalog Number: AH51218
• Chemical Name: Taprenepag
• CAS Number: 752187-80-7
• Molecular Formula: C24H22N4O5S
• Molecular Weight: 478.5203
• MDL Number: MFCD18633300
• SMILES: OC(=O)COc1cccc(c1)CN(S(=O)(=O)c1cccnc1)Cc1ccc(cc1)n1cccn1

Computed Properties

• Complexity: 753
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 34
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 10
• XLogP3: 2.5

Literature

• Effect of PF-04217329 a prodrug of a selective prostaglandin EP(2) agonist on intraocular pressure in preclinical models of glaucoma.

  Experimental eye research 20110901

• A phase 2, randomized, dose-response trial of taprenepag isopropyl (PF-04217329) versus latanoprost 0.005% in open-angle glaucoma and ocular hypertension.

  Current eye research 20110901