75621-03-3 | 3-(3-Cholamidopropyl)dimethylammonio-1-propanesulfonate

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$32.00	$22.00
25g	98%	in stock	$95.00	$67.00

Description

• Catalog Number: AI55998
• Chemical Name: 3-(3-Cholamidopropyl)dimethylammonio-1-propanesulfonate
• CAS Number: 75621-03-3
• Molecular Formula: C32H58N2O7S
• Molecular Weight: 614.8771
• MDL Number: MFCD00081083
• SMILES: O[C@@H]1CC[C@]2([C@@H](C1)C[C@H]([C@@H]1[C@@H]2C[C@H](O)[C@]2([C@H]1CC[C@@H]2[C@@H](CCC(=O)NCCC[N+](CCCS(=O)(=O)[O-])(C)C)C)C)O)C

Computed Properties

• Complexity: 1030
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 11
• Heavy Atom Count: 42
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 11
• XLogP3: 2.9

Literature

• Fabrication of an octadecylated silica monolith inside a glass microchip for protein enrichment.

  The Analyst 20121021

• [A novel method for studying nuclear localization signal-mediated nuclear translocation].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120801

• Modulation of the neurotensin solution structure in the presence of ganglioside GM1 bicelle.

  Biophysical chemistry 20120701

• Overcoming non-specific adsorption issues for AZD9164 in human urine samples: consideration of bioanalytical and metabolite identification procedures.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120415

• High-throughput screening method for lipases/esterases.

  Methods in molecular biology (Clifton, N.J.) 20120101

• Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.

  PloS one 20120101

• Lipid and membrane mimetic environments modulate spin label side chain configuration in the outer membrane protein A.

  The journal of physical chemistry. B 20111215

• Identification of Bax-voltage-dependent anion channel 1 complexes in digitonin-solubilized cerebellar granule neurons.

  Journal of neurochemistry 20111201

• Secondary structure and 1H, 13C, 15N resonance assignments of the Golgi-specific PH domain of FAPP1.

  Biomolecular NMR assignments 20111001

• Behavior of the amphiphile CHAPS alone and in combination with the biopolymer inulin in water and isopropanol-water media.

  Langmuir : the ACS journal of surfaces and colloids 20110802

• Improved technique for reconstituting incredibly high and soluble amounts of tetrameric K⁺ channel in natural membranes.

  The Journal of membrane biology 20110601

• Metal complexes as artificial proteases in proteomics: a palladium(II) complex cleaves various proteins in solutions containing detergents.

  Journal of inorganic biochemistry 20110501

• The morphology and composition of cholesterol-rich micellar nanostructures determine transmembrane protein (GPCR) activity.

  Biophysical journal 20110119

• Detergent enhancement of on-tissue protein analysis by matrix-assisted laser desorption/ionization imaging mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20110115

• Type and composition of surfactants mediating gene transfection of polyethylenimine-coated liposomes.

  International journal of nanomedicine 20110101

• Efficient production and purification of functional bacteriorhodopsin with a wheat-germ cell-free system and a combination of Fos-choline and CHAPS detergents.

  Biochemical and biophysical research communications 20101001

• Verification of surfactant CHAPS effect using AFM for making biomemory device consisting of recombinant azurin monolayer.

  Ultramicroscopy 20100501

• Study on speciation of aluminum in human serum using zwitterionic bile acid derivative dynamically coated C18 column HPLC separation with UV and on-line ICP-MS detection.

  Talanta 20100415

• Concentration-dependent aggregation of CHAPS investigated by NMR spectroscopy.

  The journal of physical chemistry. B 20100325

• Differential proteome analysis of the preeclamptic placenta using optimized protein extraction.

  Journal of biomedicine & biotechnology 20100101

• Purifying natively folded proteins from inclusion bodies using sarkosyl, Triton X-100, and CHAPS.

  BioTechniques 20100101

• A serine-type protease activity of human lens βA3-crystallin is responsible for its autodegradation.

  Molecular vision 20100101

• Production of functional bacteriorhodopsin by an Escherichia coli cell-free protein synthesis system supplemented with steroid detergent and lipid.

  Protein science : a publication of the Protein Society 20091001

• Combinatorial peptide ligand libraries for urine proteome analysis: investigation of different elution systems.

  Electrophoresis 20090701

• Characterization of fluorescent sterol binding to purified human NPC1.

  The Journal of biological chemistry 20090116

• Urea unfolding of opsin in phospholipid bicelles.

  Photochemistry and photobiology 20090101

• Receptor oligomerization and beyond: a case study in bone morphogenetic proteins.

  BMC biology 20090101

• Physicochemical properties and antioxidant activity of gamma-oryzanol-loaded liposome formulations for topical use.

  Pharmaceutical development and technology 20090101

• Ion-exclusion/cation-exchange chromatographic determination of common inorganic ions in human saliva by using an eluent containing zwitterionic surfactant.

  Journal of chromatography. A 20081212

• Additive action of two or more solutes on lipid membranes.

  Langmuir : the ACS journal of surfaces and colloids 20080819

• Pharmacological characterization of cellular mechanisms of the renal vasodilatory effect of nicotine in rats.

  European journal of pharmacology 20080707

• Blending effects on adsorption and micellization of different membrane protein solubilizers II. A thermodynamic study on a mixed system of CHAPS with a bile salt in pH 7.4 phosphate buffer solution.

  Colloids and surfaces. B, Biointerfaces 20080315

• Identification of Pasteurella multocida CHAPS-soluble outer membrane proteins.

  Avian diseases 20080301

• Sequential extraction of proteins by chemical reagents.

  Methods in molecular biology (Clifton, N.J.) 20080101

• Solubilization of human serotonin 1A receptors expressed in neuronal cells.

  Chemistry and physics of lipids 20071201

• Wash-free in-situ self-desalting and peptide enrichment by block copolymer analyzed with MALDI-TOFMS.

  Chemical communications (Cambridge, England) 20071121

• P-glycoprotein in proteoliposomes with low residual detergent: the effects of cholesterol.

  Pharmaceutical research 20071101

• Solubilization of the ecdysone binding protein from anterior silk gland cell membranes of the silkworm, Bombyx mori.

  Zoological science 20071001

• A modified enzyme-linked immunosorbent assay adapted for immunodetection of low amounts of water-insoluble proteins.

  Journal of immunological methods 20070930

• Cdk5--p39 is a labile complex with the similar substrate specificity to Cdk5--p35.

  Journal of neurochemistry 20070901

• In vitro stabilization and minimum active component of polygalacturonic acid synthase involved in pectin biosynthesis.

  Bioscience, biotechnology, and biochemistry 20070901

• Cholesterol depletion alters detergent-specific solubility profiles of selected tight junction proteins and the phosphorylation of occludin.

  Experimental cell research 20070715

• On the adsorption properties of surface chemically pure CHAPS at the air/water interface.

  Langmuir : the ACS journal of surfaces and colloids 20070605

• Expression and functional activity of ryanodine receptors (RyRs) during skeletal muscle development.

  Cell calcium 20070601

• Molecularly imprinted poly beta-cyclodextrin polymer: application in protein refolding.

  Biochimica et biophysica acta 20070601

• High sensitivity identification of membrane proteins by MALDI TOF-MASS spectrometry using polystyrene beads.

  Journal of proteome research 20070401

• Catalytic properties of MGAT3, a putative triacylgycerol synthase.

  Journal of lipid research 20070301

• The use of ASB-14 in combination with CHAPS is the best for solubilization of human brain proteins for two-dimensional gel electrophoresis.

  Briefings in functional genomics & proteomics 20070301

• Protein extraction from Mycobacterium avium subsp. paratuberculosis: Comparison of methods for analysis by sodium dodecyl sulphate polyacrylamide gel electrophoresis, native PAGE and surface enhanced laser desorption/ionization time of flight mass spectrometry.

  Journal of microbiological methods 20070101

• The membrane-induced structure of melittin is correlated with the fluidity of the lipids.

  Biochimica et biophysica acta 20070101

• Partitioning of myelin basic protein into membrane microdomains in a spontaneously demyelinating mouse model for multiple sclerosis.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20061201

• Lipid phosphate phosphatases 1 and 3 are localized in distinct lipid rafts.

  Journal of biochemistry 20061101

• Assessment of endothelium-dependent vasodilation in equine digital resistance vessels.

  Journal of veterinary pharmacology and therapeutics 20061001

• Micelle formation of bile salts and zwitterionic derivative as studied by two-dimensional NMR spectroscopy.

  Chemistry and physics of lipids 20060701

• Stimulation of polyprenyl 4-hydroxybenzoate transferase activity by sodium cholate and 3-[(cholamidopropyl)dimethylammonio]-1-propanesulfonate.

  Analytical biochemistry 20060601

• Comparison of extraction procedures for proteome analysis of Streptococcus pneumoniae and a basic reference map.

  Proteomics 20060601

• Efficient solubilization buffers for two-dimensional gel electrophoresis of acidic and basic proteins extracted from wheat seeds.

  Biochimica et biophysica acta 20060401

• Improvement of interfacial protein stability by CHAPS.

  Biotechnology letters 20060401

• A quantitative and selective chromatography method for determining coverages of multiple proteins on surfaces.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051105

• MHC II molecules and invariant chain reside in membranes distinct from conventional lipid rafts.

  Journal of leukocyte biology 20051101

• Blending effects on adsorption and micellization of different membrane protein solubilizers: a thermodynamic study on three mixed systems of CHAPS with MEGA-8, -9 and -10 in pH 7.2 phosphate buffer solution.

  Colloids and surfaces. B, Biointerfaces 20051010

• Effective permeability of hydrophilic substances through walls of lymph vessels: roles of endothelial barrier.

  American journal of physiology. Heart and circulatory physiology 20051001

• Process of destruction of large unilamellar vesicles by a zwitterionic detergent, CHAPS: partition behavior between membrane and water phases.

  Chemical & pharmaceutical bulletin 20050901

• Magnetic resonance investigations of lipid motion in isotropic bicelles.

  Langmuir : the ACS journal of surfaces and colloids 20050816

• Identification and active expression of the Mycobacterium tuberculosis gene encoding 5-phospho-{alpha}-d-ribose-1-diphosphate: decaprenyl-phosphate 5-phosphoribosyltransferase, the first enzyme committed to decaprenylphosphoryl-d-arabinose synthesis.

  The Journal of biological chemistry 20050701

• Effect of detergents and hexafluoroisopropanol on the conformation of a non-helical and a helical plant protease inhibitor.

  International journal of biological macromolecules 20050701

• Structure at 1.6 A resolution of the protein from gene locus At3g22680 from Arabidopsis thaliana.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20050701

• Postulated role of interdomain interactions within the type 1 ryanodine receptor in the low gain of Ca2+-induced Ca2+ release activity of mammalian skeletal muscle sarcoplasmic reticulum.

  American journal of physiology. Cell physiology 20050601

• Triton X-100 inhibition of yeast plasma membrane associated NADH-dependent redox activities.

  Journal of enzyme inhibition and medicinal chemistry 20050401

• 3-O-alkyl-D-glucose derivatives induce fruit bodies of Pleurotus ostreatus.

  Mycological research 20050301

• Improvement of two-dimensional gel electrophoresis proteome maps of the haloarchaeon Haloferax volcanii.

  Proteomics 20050201

• Reconstitution of glycopeptide export in mixed detergent-solubilised and resealed microsomes depleted of lumenal components.

  Journal of biochemical and biophysical methods 20050131

• A colorimetric determination for glycosidic and bile salt-based detergents: applications in membrane protein research.

  Analytical biochemistry 20050101

• Francisella tularensis proteome: low levels of ASB-14 facilitate the visualization of membrane proteins in total protein extracts.

  Journal of proteome research 20050101

• Exploring the hidden human urinary proteome via ligand library beads.

  Journal of proteome research 20050101

• Functional characterization of rhodopsin monomers and dimers in detergents.

  The Journal of biological chemistry 20041224

• Cell-free synthesis of a functional ion channel in the absence of a membrane and in the presence of detergent.

  Biochemistry 20041005

• Modified micellar electrokinetic chromatography in the analysis of catechins and xanthines in chocolate.

  Electrophoresis 20041001

• [Effect of CHAPS on the stability of Spirulina platensis phycobilisomes].

  Guang pu xue yu guang pu fen xi = Guang pu 20041001

• Effect of membrane perturbants on the activity and phase distribution of inositol phosphorylceramide synthase; development of a novel assay.

  Biochemistry 20040706

• RyR1 exhibits lower gain of CICR activity than RyR3 in the SR: evidence for selective stabilization of RyR1 channel.

  American journal of physiology. Cell physiology 20040701

• Annular alpha-synuclein species from purified multiple system atrophy inclusions.

  Journal of neurochemistry 20040701

• Adsorption of bovine alpha-lactalbumin on suspended solid nanospheres and its subsequent displacement studied by NMR spectroscopy.

  Langmuir : the ACS journal of surfaces and colloids 20040622

• Sigma-2 receptors are specifically localized to lipid rafts in rat liver membranes.

  European journal of pharmacology 20040616

• Mechanism of formation of multilayered 2D crystals of the enzyme IIC-mannitol transporter.

  Biochimica et biophysica acta 20040527

• Long-chain fatty acid uptake into adipocytes depends on lipid raft function.

  Biochemistry 20040413

• Solubilization of serotonin1A receptors heterologously expressed in Chinese hamster ovary cells.

  Cellular and molecular neurobiology 20040401

• Mechanisms underlying endothelium-dependent flow increase in perfused rat mesenteric vascular bed.

  European journal of pharmacology 20040206

• Purification and characterization of the recombinant human dopamine D2S receptor from Pichia pastoris.

  Protein expression and purification 20040201

• Topology of the maize mixed linkage (1->3),(1->4)-beta-d-glucan synthase at the Golgi membrane.

  Plant physiology 20040201

• [Transformation of phospholipids by cabbage phospholipase D in mixed micelles containing 3-[(3-cholamidopropyl)dimethylammonio]propanesulfonate].

  Prikladnaia biokhimiia i mikrobiologiia 20040101

• Molecular heterogeneity of a type III cytotoxin, Pseudomonas aeruginosa exoenzyme S.

  Biochemistry 20031209

• Towards global analysis of mosquito chorion proteins through sequential extraction, two-dimensional electrophoresis and mass spectrometry.

  Proteomics 20031001

• Both raft- and non-raft proteins associate with CHAPS-insoluble complexes: some APP in large complexes.

  Biochemical and biophysical research communications 20030905

• Characterization of the N-acetylaspartate biosynthetic enzyme from rat brain.

  Journal of neurochemistry 20030801

• Use of chiral zwitterionic surfactants for enantiomeric resolutions by capillary electrophoresis.

  Electrophoresis 20030801

• Syntaxin is efficiently excluded from sphingomyelin-enriched domains in supported lipid bilayers containing cholesterol.

  The Journal of membrane biology 20030801

• Solubilization of adenylyl cyclase from human myometrium in a alphas-coupled form.

  Bioscience reports 20030801

• Enhanced resolution of glycosylphosphatidylinositol-anchored and transmembrane proteins from the lipid-rich myelin membrane by two-dimensional gel electrophoresis.

  Proteomics 20030701

• Solubilisation and properties of the sialate-4-O-acetyltransferase from guinea pig liver.

  Biological chemistry 20030701

• A role for native lipids in the stabilization and two-dimensional crystallization of the Escherichia coli NADH-ubiquinone oxidoreductase (complex I).

  The Journal of biological chemistry 20030523

• Modulation of the interactions of isolated ryanodine receptors of rabbit skeletal muscle by Na+ and K+.

  Biochemistry 20030513

• The multidrug resistance protein ABCC1 drug-binding domains show selective sensitivity to mild detergents.

  Biochemical and biophysical research communications 20030418

• Aluminum exchange between citrate and human serum transferrin and interaction with transferrin receptor 1.

  Biochemistry 20030318

• The dual role of CHAPS in the crystallization of stromelysin-3 catalytic domain.

  Acta crystallographica. Section D, Biological crystallography 20030301

• A sensitive and robust method for obtaining intermolecular NOEs between side chains in large protein complexes.

  Journal of biomolecular NMR 20030301

• Characterization of the NTPDase activities in the mesentery pre- and post-capillary circuits of the guinea pig.

  Canadian journal of physiology and pharmacology 20030301

• Immune response of the tammar wallaby (Macropus eugenii) to sperm antigens.

  Reproduction, fertility, and development 20030101

• Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane.

  Cell 20021101

• Presence of detergent-resistant microdomains in lysosomal membranes.

  Biochemical and biophysical research communications 20021018

• Allosteric transitions of Torpedo acetylcholine receptor in lipids, detergent and amphipols: molecular interactions vs. physical constraints.

  FEBS letters 20020925

• Localization and roles in fertilization of sperm proteasomes in the ascidian Halocynthia roretzi.

  Molecular reproduction and development 20020601

• Detergent-insoluble glycosphingolipid/cholesterol microdomains of the myelin membrane.

  Journal of neurochemistry 20020601

• Removal of detergents from protein extracts using activated charcoal prior to immunological analysis.

  Journal of immunological methods 20020601

• Cholate-induced dimerization of detergent- or phospholipid-solubilized bovine cytochrome C oxidase.

  Biochemistry 20020402

• Monomers of the catalytic domain of human neuropathy target esterase are active in the presence of phospholipid.

  The Biochemical journal 20020101

• Solubilization of high affinity G-protein-coupled serotonin1A receptors from bovine hippocampus using pre-micellar CHAPS at low concentration.

  Molecular membrane biology 20020101

• Solubilisation and immunoprecipitation of rat striatal adenosine A(2A) receptors.

  European journal of pharmacology 20011116

• Human acyl-CoA:diacylglycerol acyltransferase is a tetrameric protein.

  The Biochemical journal 20011101

• Determination of bisphenol A and 10 alkylphenols in serum using SDS micelle capillary electrophoresis with gamma-cyclodextrin.

  Biomedical chromatography : BMC 20011101

• Purification and characterization of the Sin Nombre virus nucleocapsid protein expressed in Escherichia coli.

  Protein expression and purification 20011001

• Chloroplast biogenesis 84: solubilization and partial purification of membrane-bound [4-vinyl]chlorophyllide a reductase from etiolated barley leaves.

  Analytical biochemistry 20010815

• Continuous recording of long-chain acyl-coenzyme a synthetase activity using fluorescently labeled bovine serum albumin.

  Analytical biochemistry 20010801

• Renin uptake by the endothelium mediates vascular angiotensin formation.

  Hypertension (Dallas, Tex. : 1979) 20010801

• Effect of surfactants and natural detergents on phosphatidylcholine synthesis in photoreceptor membranes.

  Membrane & cell biology 20010701

• Phospholipid flippase activity of the reconstituted P-glycoprotein multidrug transporter.

  Biochemistry 20010612

• Effects of the incorporation of CHAPS into SDS micelles on neuropeptide-micelle binding: separation of the role of electrostatic interactions from hydrophobic interactions.

  Biopolymers 20010601

• Novel properties of the nucleolar targeting signal of human angiogenin.

  Biochemical and biophysical research communications 20010601

• Alkylation kinetics of proteins in preparation for two-dimensional maps: a matrix assisted laser desorption/ionization-mass spectrometry investigation.

  Electrophoresis 20010601

• Involvement of the neurotensin receptor subtype NTR3 in the growth effect of neurotensin on cancer cell lines.

  International journal of cancer 20010515

• Structure and function in bacteriorhodopsin: the role of the interhelical loops in the folding and stability of bacteriorhodopsin.

  Journal of molecular biology 20010427

• Structure and function in bacteriorhodopsin: the effect of the interhelical loops on the protein folding kinetics.

  Journal of molecular biology 20010427

• Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells.

  The Journal of biological chemistry 20010413

• The 18 kDa antigen of Theileria equi is a specific but less abundant protein also expressed by parasites cultured in vitro.

  Veterinary research communications 20010401

• Incomplete dialysis of protein samples containing 3-[(3-chlolamidopropyl)dimethylammonio]-1-propanesulfonate may lead to erroneous estimation of histidine content on amino acid analysis.

  Analytical biochemistry 20010301

• Inhibitory effects of detergents on rat CYP1A1-dependent monooxygenase: comparison of mixed and fused systems consisting of rat CYP 1A1 and yeast NADPH-P450 reductase.

  Biochemical and biophysical research communications 20010209

• Specific binding of proinsulin C-peptide to intact and to detergent-solubilized human skin fibroblasts.

  Biochemical and biophysical research communications 20010119

• Characterization of the ATPase activity of the Mr 170,000 to 180,000 membrane glycoprotein (P-glycoprotein) associated with multidrug resistance in K562/ADM cells.

  Cancer research 19880901