75738-58-8 | Cefmenoxime hydrochloride

Packsize	Purity	Availability	Price	Discounted Price
25mg	98%	in stock	$44.00	$31.00
100mg	98%	in stock	$114.00	$80.00
500mg	98%	in stock	$345.00	$241.00

Description

• Catalog Number: AB52214
• Chemical Name: Cefmenoxime hydrochloride
• CAS Number: 75738-58-8
• Molecular Formula: C16H18ClN9O5S3
• Molecular Weight: 548.0194200000001
• MDL Number: MFCD01750403
• SMILES: CON=C(C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)CSc1nnnn1C)c1csc(n1)N.Cl

Computed Properties

• Complexity: 890
• Covalently-Bonded Unit Count: 3
• Defined Atom Stereocenter Count: 4
• Defined Bond Stereocenter Count: 2
• Heavy Atom Count: 67
• Hydrogen Bond Acceptor Count: 28
• Hydrogen Bond Donor Count: 7
• Rotatable Bond Count: 16

Literature

• In vitro assessment of the cytotoxicity of six topical antibiotics to four cultured ocular surface cell lines.

  Biocontrol science 20120601

• [Drug sensitivity of causative agents in ocular infection of external adnexa and anterior segments--multicenter study of causative agents and drug sensitivity of ocular infection by the Japanese Association for Ocular Infection part II].

  Nippon Ganka Gakkai zasshi 20110901

• Acute encephalopathy in a child with secondary carnitine deficiency due to pivalate-conjugated antibiotics.

  The Pediatric infectious disease journal 20110101

• [Evaluation of antimicrobial prophylaxis after normal delivery].

  The Japanese journal of antibiotics 20090401

• Pharmacokinetics and bioequivalence studies of cefteram pivoxil in healthy Chinese volunteers.

  European journal of drug metabolism and pharmacokinetics 20090101

• Pharmacokinetic and bioequivalence comparison of a single 100-mg dose of cefteram pivoxil powder suspension and tablet formulations: a randomized-sequence, open-label, two-period crossover study in healthy Chinese adult male volunteers.

  Clinical therapeutics 20080401

• Ceftezole, a cephem antibiotic, is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity.

  International journal of molecular medicine 20070901

• In vitro synergistic effects of double combinations of beta-lactams and azithromycin against clinical isolates of Neisseria gonorrhoeae.

  Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20060801

• Enhancement of antimicrobial activities of cefteram or clavulanic acid/amoxicillin against cefixime-resistant Neisseria gonorrhoeae in the presence of clarithromycin or azithromycin.

  Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20060801

• [The effect of preoperative topical antibiotics in cataract surgery].

  Nippon Ganka Gakkai zasshi 20060701

• Characteristics of Pseudomonas corneal infection related to orthokeratology.

  Cornea 20051001

• Hepatic natural killer and natural killer T cells markedly decreased in two cases of drug-induced fulminant hepatic failure rescued by living donor liver transplantation.

  Journal of gastroenterology and hepatology 20050701

• [Antimicrobial susceptibility surveillance of Streptococcus pneumoniae and Haemophilus influenzae isolates to cefteram and other antimicrobial drugs during January 2003 to July 2004].

  The Japanese journal of antibiotics 20041201

• Comparative clinical study of cefcapene pivoxil and cefteram pivoxil in chronic respiratory tract infections by a double-blind method.

  The Journal of international medical research 20040101

• Heterogeneity of IgE response to cefteram pivoxil was noted in 2 patients with cefteram-induced occupational asthma.

  The Journal of allergy and clinical immunology 20030701

• [Antibiotic ophthalmic solutions evaluated by pharmacokinetic parameters of maximum concentration in the aqueous].

  Nippon Ganka Gakkai zasshi 20020401

• Effects of the quantity of water and milk ingested concomitantly with AS-924, a novel ester-type cephem antibiotic, on its pharmacokinetics.

  International journal of antimicrobial agents 20011101

• Effect of antacid pretreatment on the pharmacokinetics of AS-924, a novel ester-type cephem antibiotic--comparison with cefteram-pivoxil.

  International journal of antimicrobial agents 20011101

• Evaluation of oral antimicrobial agent levels in tooth extraction sites.

  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20010601

• [Antibacterial activities of cefmenoxime against recent fresh clinical isolates from patients in sinusitis].

  The Japanese journal of antibiotics 19950501

• Pharmacoeconomic analysis of cefmenoxime dual individualization in the treatment of nosocomial pneumonia.

  The Annals of pharmacotherapy 19940301

• Cefmenoxime in corneal organ culture.

  Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 19940101

• Therapeutic efficacy of chloramphenicol, co-trimoxazole (trimethoprim/sulphamethoxazole), cefmenoxime and ceftriaxone in experimental bacteraemia and meningitis caused by ampicillin-resistant Haemophilus influenzae type b.

  The Journal of antimicrobial chemotherapy 19881101

• Cefmenoxime (SCE-1365), a novel broad-spectrum cephalosporin: in vitro and in vivo antibacterial activities.

  Antimicrobial agents and chemotherapy 19810101