7597-18-4 | 6-Nitroindazole

Packsize	Purity	Availability	Price	Discounted Price
1g	99%	in stock	$15.00	$10.00
5g	95%	in stock	$17.00	$12.00
25g	95%	in stock	$30.00	$21.00
100g	97%	in stock	$90.00	$63.00
250g	>98.0%(GC)	in stock	$179.00	$126.00

Description

• Catalog Number: AB69986
• Chemical Name: 6-Nitroindazole
• CAS Number: 7597-18-4
• Molecular Formula: C7H5N3O2
• Molecular Weight: 163.1335
• MDL Number: MFCD00005695
• SMILES: [O-][N+](=O)c1ccc2c(c1)[nH]nc2

Computed Properties

• Complexity: 192
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• XLogP3: 2.1

Literature

• Nitroindazole compounds inhibit the oxidative activation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin to neurotoxic pyridinium cations by human monoamine oxidase (MAO).

  Free radical research 20091001

• Fluorinated indazoles as novel selective inhibitors of nitric oxide synthase (NOS): synthesis and biological evaluation.

  Bioorganic & medicinal chemistry 20090901

• Activities of 7-nitroindazole and 1-(2-(trifluoromethylphenyl)-imidazole independent of neuronal nitric-oxide synthase inhibition.

  The Journal of pharmacology and experimental therapeutics 20080501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Conformational changes in nitric oxide synthases induced by chlorzoxazone and nitroindazoles: crystallographic and computational analyses of inhibitor potency.

  Biochemistry 20021126